TSIB_1527 a8f33d30029d10bbbb3429668a98e218 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 124 280 1.0E-71 T 23-10-2018 TSIB_1527 a8f33d30029d10bbbb3429668a98e218 281 SUPERFAMILY SSF51556 1 278 7.53E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_1527 a8f33d30029d10bbbb3429668a98e218 281 Pfam PF01026 TatD related DNase 4 275 7.7E-30 T 23-10-2018 IPR001130 TatD family GO:0016788 TSIB_1527 a8f33d30029d10bbbb3429668a98e218 281 PIRSF PIRSF004961 1 281 1.0E-115 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 TSIB_1527 a8f33d30029d10bbbb3429668a98e218 281 Gene3D G3DSA:3.20.20.140 2 280 1.3E-27 T 23-10-2018 TSIB_0781 c1af8e9d5fdcce6ee390f621e08c5884 541 SUPERFAMILY SSF52540 143 524 4.23E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0781 c1af8e9d5fdcce6ee390f621e08c5884 541 Gene3D G3DSA:1.10.390.40 81 159 1.3E-57 T 23-10-2018 TSIB_0781 c1af8e9d5fdcce6ee390f621e08c5884 541 Pfam PF00437 Type II/IV secretion system protein 162 407 5.9E-47 T 23-10-2018 IPR001482 Type II/IV secretion system protein TSIB_0781 c1af8e9d5fdcce6ee390f621e08c5884 541 Gene3D G3DSA:3.40.50.300 260 537 1.8E-87 T 23-10-2018 TSIB_0781 c1af8e9d5fdcce6ee390f621e08c5884 541 Gene3D G3DSA:3.30.450.370 46 257 1.3E-57 T 23-10-2018 TSIB_0936 da66c2002e114311fe949ce11bead121 502 Gene3D G3DSA:3.40.640.10 88 315 2.4E-61 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0936 da66c2002e114311fe949ce11bead121 502 Gene3D G3DSA:3.90.1150.10 340 475 4.7E-44 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0936 da66c2002e114311fe949ce11bead121 502 SUPERFAMILY SSF53383 21 488 3.36E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0936 da66c2002e114311fe949ce11bead121 502 Pfam PF02347 Glycine cleavage system P-protein 36 306 2.7E-9 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSIB_0936 da66c2002e114311fe949ce11bead121 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 13 490 61.228 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 63 893 1.4E-223 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 SMART SM00863 700 743 8.1E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Gene3D G3DSA:2.40.30.130 504 597 5.2E-31 T 23-10-2018 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Gene3D G3DSA:3.30.54.20 673 724 7.5E-29 T 23-10-2018 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 6 910 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Pfam PF02272 DHHA1 domain 782 911 5.3E-19 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 SUPERFAMILY SSF101353 312 503 4.71E-46 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 SUPERFAMILY SSF50447 514 593 2.82E-18 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Gene3D G3DSA:3.30.930.10 3 262 1.5E-110 T 23-10-2018 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Gene3D G3DSA:3.30.980.10 603 672 3.2E-20 T 23-10-2018 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 SUPERFAMILY SSF55681 59 266 1.11E-57 T 23-10-2018 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Pfam PF01411 tRNA synthetases class II (A) 63 601 5.9E-144 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 PRINTS PR00980 Alanyl-tRNA synthetase signature 129 140 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 PRINTS PR00980 Alanyl-tRNA synthetase signature 362 375 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 PRINTS PR00980 Alanyl-tRNA synthetase signature 247 260 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 PRINTS PR00980 Alanyl-tRNA synthetase signature 338 354 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 SUPERFAMILY SSF55186 601 750 2.75E-47 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 700 742 1.6E-14 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 6 908 23.38 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_1812 db1fa068fedf408ed99781b3f8e84183 911 Gene3D G3DSA:3.10.310.40 811 911 6.8E-23 T 23-10-2018 TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 SUPERFAMILY SSF160467 4 93 1.1E-21 T 23-10-2018 TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 1.1E-69 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 201 6.0E-75 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 SUPERFAMILY SSF50891 88 218 1.06E-46 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 Gene3D G3DSA:2.40.100.10 87 227 2.3E-60 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 Gene3D G3DSA:3.30.1360.40 4 81 1.0E-23 T 23-10-2018 TSIB_0729 8e39fe85a26c12831508cfc2099fde6c 230 SMART SM00796 3 202 7.4E-103 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 Gene3D G3DSA:3.40.50.720 41 236 5.1E-71 T 23-10-2018 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 41 218 1.1E-51 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 SUPERFAMILY SSF51735 42 232 3.32E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 SUPERFAMILY SSF48179 238 329 3.4E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 Gene3D G3DSA:3.40.50.720 270 458 1.5E-69 T 23-10-2018 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 353 442 2.1E-25 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 SUPERFAMILY SSF52413 345 441 5.23E-25 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 PIRSF PIRSF000124 40 446 7.5E-85 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 PIRSF PIRSF500136 30 455 1.7E-145 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 239 325 6.2E-26 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 41 438 5.7E-128 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSIB_1921 7ca6059b72be208e910cd6d0fce5e774 458 SMART SM00984 352 443 2.6E-34 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_1867 2d9045a899a8821094293d3a2ad23ae7 61 SUPERFAMILY SSF46785 6 58 1.26E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1867 2d9045a899a8821094293d3a2ad23ae7 61 Gene3D G3DSA:1.10.10.10 2 58 3.5E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1416 5e2ca404eab73a322ef34b06939f22e0 235 PIRSF PIRSF005928 10 233 9.8E-102 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase TSIB_1416 5e2ca404eab73a322ef34b06939f22e0 235 Gene3D G3DSA:3.30.460.10 19 89 1.1E-7 T 23-10-2018 TSIB_1416 5e2ca404eab73a322ef34b06939f22e0 235 Pfam PF01909 Nucleotidyltransferase domain 30 86 3.7E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1416 5e2ca404eab73a322ef34b06939f22e0 235 SUPERFAMILY SSF81301 22 69 9.45E-9 T 23-10-2018 TSIB_1536 6cd88ba9572e82396432914b336581ef 157 SUPERFAMILY SSF51230 81 156 3.66E-26 T 23-10-2018 IPR011053 Single hybrid motif TSIB_1536 6cd88ba9572e82396432914b336581ef 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSIB_1536 6cd88ba9572e82396432914b336581ef 157 Gene3D G3DSA:2.40.50.100 85 157 3.1E-29 T 23-10-2018 TSIB_1536 6cd88ba9572e82396432914b336581ef 157 Pfam PF00364 Biotin-requiring enzyme 90 156 4.4E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 158 45.961 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 Gene3D G3DSA:3.50.20.10 44 156 9.2E-33 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 PIRSF PIRSF005216 2 158 1.1E-47 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 155 8.7E-41 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 142 5.0E-67 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 Gene3D G3DSA:3.30.60.30 1 43 1.1E-19 T 23-10-2018 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 155 6.1E-42 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0849 648f98ed6ed19d8d6eb23a028c206c0e 158 SUPERFAMILY SSF56271 2 155 5.49E-43 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 305 2.7E-74 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 Pfam PF05834 Lycopene cyclase protein 8 367 3.4E-17 T 23-10-2018 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 SUPERFAMILY SSF51905 3 345 5.3E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.2E-10 T 23-10-2018 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 1.2E-10 T 23-10-2018 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.2E-10 T 23-10-2018 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 5 397 39.296 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 Gene3D G3DSA:3.50.50.60 7 342 2.1E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0988 8c7d363b81b6a68c721456cd8251b527 397 Gene3D G3DSA:3.30.9.10 73 359 2.1E-107 T 23-10-2018 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Gene3D G3DSA:3.40.1190.20 215 482 1.3E-72 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 217 479 2.0E-72 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 PIRSF PIRSF017184 4 484 2.6E-94 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Gene3D G3DSA:3.40.50.10260 14 208 8.6E-41 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 203 18.533 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Pfam PF01256 Carbohydrate kinase 232 474 1.8E-52 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 420 430 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 12 188 1.8E-41 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Pfam PF03853 YjeF-related protein N-terminus 27 187 3.1E-33 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 SUPERFAMILY SSF64153 5 230 7.32E-47 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 SUPERFAMILY SSF53613 220 479 2.25E-57 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1969 92759367ce8cc48629ae2be1fcd12305 485 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 202 484 21.104 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 8.7E-38 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 Gene3D G3DSA:3.40.50.720 92 282 1.8E-129 T 23-10-2018 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 4.2E-70 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 SUPERFAMILY SSF51735 99 281 4.71E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 Gene3D G3DSA:3.40.50.720 7 298 1.8E-129 T 23-10-2018 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 SUPERFAMILY SSF52283 1 134 3.02E-37 T 23-10-2018 TSIB_1017 d80e32df513c50720f3b65666c1dc564 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 Gene3D G3DSA:3.40.462.40 271 419 3.5E-29 T 23-10-2018 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 Pfam PF01565 FAD binding domain 54 191 5.3E-41 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 SUPERFAMILY SSF56176 6 228 4.63E-55 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 SUPERFAMILY SSF55103 239 464 3.76E-31 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 462 3.8E-35 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 Gene3D G3DSA:3.30.465.40 11 247 9.0E-67 T 23-10-2018 TSIB_0773 75ea9c75b2659aac92213e7355fe3d21 465 Gene3D G3DSA:1.10.45.10 425 463 2.4E-6 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSIB_1257 2f434a9584e2ea23adb499ad3a4ddb22 262 SMART SM00382 26 211 5.7E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1257 2f434a9584e2ea23adb499ad3a4ddb22 262 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1257 2f434a9584e2ea23adb499ad3a4ddb22 262 SUPERFAMILY SSF52540 2 219 6.86E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1257 2f434a9584e2ea23adb499ad3a4ddb22 262 Gene3D G3DSA:3.40.50.300 1 245 8.1E-67 T 23-10-2018 TSIB_1257 2f434a9584e2ea23adb499ad3a4ddb22 262 Pfam PF00005 ABC transporter 27 162 1.6E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Gene3D G3DSA:3.30.1330.30 268 364 8.7E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 9 363 1.0E-109 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Gene3D G3DSA:3.30.420.60 141 265 1.1E-34 T 23-10-2018 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Gene3D G3DSA:2.30.30.870 8 138 1.2E-41 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Hamap MF_01853 Protein pelota homolog [pelA]. 10 363 36.685 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 SUPERFAMILY SSF159065 10 136 1.96E-39 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 SMART SM01194 9 137 2.0E-50 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 SUPERFAMILY SSF55315 259 363 2.21E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Pfam PF03464 eRF1 domain 2 146 256 1.1E-14 T 23-10-2018 IPR005141 eRF1 domain 2 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Pfam PF03465 eRF1 domain 3 269 363 1.7E-23 T 23-10-2018 IPR005142 eRF1 domain 3 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 SUPERFAMILY SSF53137 139 267 2.62E-30 T 23-10-2018 TSIB_1185 3bac734d7da7f12da3b2b71fe3833e91 364 Pfam PF03463 eRF1 domain 1 11 135 1.8E-32 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TSIB_0428 3a82eae7769ca5119444befa951265c2 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 6.1E-27 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 Gene3D G3DSA:3.20.20.70 1 206 8.7E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 Pfam PF01380 SIS domain 246 347 1.0E-20 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 220 406 3.0E-74 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 SUPERFAMILY SSF53697 215 404 1.06E-39 T 23-10-2018 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 SMART SM00934 2 203 3.5E-42 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 3.2E-82 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 SUPERFAMILY SSF51366 2 212 1.04E-42 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSIB_0428 3a82eae7769ca5119444befa951265c2 406 Gene3D G3DSA:3.40.50.10490 213 406 3.0E-58 T 23-10-2018 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 Gene3D G3DSA:3.40.50.261 130 286 5.3E-57 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 SUPERFAMILY SSF51735 2 126 1.93E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 SUPERFAMILY SSF52210 290 436 5.63E-36 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 Pfam PF13380 CoA binding domain 9 129 2.1E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 Gene3D G3DSA:3.40.50.261 288 441 1.3E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 Gene3D G3DSA:3.40.50.720 1 125 2.0E-28 T 23-10-2018 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 SMART SM00881 4 98 2.0E-18 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 SUPERFAMILY SSF52210 128 283 2.75E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1837 e9667f7c75914badf81e37bdb2919c60 448 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 5.9E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSIB_1886 1ae19cf96f92f63f193e01beb32a1515 267 SUPERFAMILY SSF53850 2 260 1.73E-50 T 23-10-2018 TSIB_1886 1ae19cf96f92f63f193e01beb32a1515 267 Gene3D G3DSA:3.40.190.10 4 259 5.1E-75 T 23-10-2018 TSIB_1886 1ae19cf96f92f63f193e01beb32a1515 267 Gene3D G3DSA:3.40.190.120 104 207 5.1E-75 T 23-10-2018 TSIB_1886 1ae19cf96f92f63f193e01beb32a1515 267 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 2 259 2.9E-46 T 23-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TSIB_1636 28f7cfab95ce429c753d2dcd3d66e91d 140 Gene3D G3DSA:3.30.1330.80 7 139 5.2E-31 T 23-10-2018 TSIB_1636 28f7cfab95ce429c753d2dcd3d66e91d 140 Pfam PF03479 Domain of unknown function (DUF296) 10 111 2.3E-20 T 23-10-2018 IPR005175 PPC domain TSIB_1636 28f7cfab95ce429c753d2dcd3d66e91d 140 SUPERFAMILY SSF117856 8 131 4.45E-26 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.251 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SUPERFAMILY SSF50447 259 375 6.09E-32 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Gene3D G3DSA:3.30.230.10 472 720 1.1E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Gene3D G3DSA:3.40.50.300 7 222 1.9E-71 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SUPERFAMILY SSF54980 388 463 1.4E-21 T 23-10-2018 IPR035647 EF-G domain III/V-like TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Gene3D G3DSA:3.30.70.870 388 465 1.6E-26 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Pfam PF03764 Elongation factor G, domain IV 513 618 9.0E-26 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Pfam PF00679 Elongation factor G C-terminus 621 704 9.7E-23 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Pfam PF14492 Elongation Factor G, domain II 387 459 2.4E-25 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 154 1.7E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SUPERFAMILY SSF52540 9 261 6.69E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SMART SM00838 621 708 4.5E-42 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Gene3D G3DSA:2.40.30.10 259 386 7.1E-27 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SUPERFAMILY SSF54211 463 623 1.39E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Gene3D G3DSA:3.30.70.240 466 718 1.1E-72 T 23-10-2018 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SUPERFAMILY SSF54980 624 716 2.49E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 7.7E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 SMART SM00889 505 619 5.3E-19 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSIB_1514 19707e5ceb7ad17c77ae236681b7e445 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 4.7E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSIB_1721 b257d327693ed40949d5ad164a85928f 243 SMART SM00382 28 218 7.2E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1721 b257d327693ed40949d5ad164a85928f 243 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1721 b257d327693ed40949d5ad164a85928f 243 Gene3D G3DSA:3.40.50.300 3 241 2.4E-57 T 23-10-2018 TSIB_1721 b257d327693ed40949d5ad164a85928f 243 Pfam PF00005 ABC transporter 19 169 7.0E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1721 b257d327693ed40949d5ad164a85928f 243 SUPERFAMILY SSF52540 3 227 2.0E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1721 b257d327693ed40949d5ad164a85928f 243 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 239 7.3E-87 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TSIB_1130 e241022c613bcaecb39763b906a39739 204 Pfam PF01976 Protein of unknown function DUF116 23 180 5.2E-44 T 23-10-2018 IPR002829 Protein of unknown function DUF116 TSIB_1130 e241022c613bcaecb39763b906a39739 204 PIRSF PIRSF006594 1 186 1.1E-64 T 23-10-2018 IPR002829 Protein of unknown function DUF116 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Gene3D G3DSA:3.90.740.10 170 337 5.7E-247 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 SUPERFAMILY SSF52374 4 576 3.33E-126 T 23-10-2018 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 859 1.0E-276 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Pfam PF08264 Anticodon-binding domain of tRNA 612 760 5.7E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 SUPERFAMILY SSF50677 187 335 7.46E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 SUPERFAMILY SSF47323 583 822 2.62E-57 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 567 2.0E-145 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Gene3D G3DSA:3.40.50.620 22 532 5.7E-247 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 791 28.856 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 Gene3D G3DSA:1.10.730.10 2 748 5.7E-247 T 23-10-2018 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 4.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 483 501 4.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 4.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 4.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0968 66d803a141e58f22e0c77062cfdc1a8d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 452 473 4.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Gene3D G3DSA:1.10.730.10 682 801 1.1E-32 T 23-10-2018 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Gene3D G3DSA:3.30.2320.20 826 958 4.1E-46 T 23-10-2018 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 4 958 17.947 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 6 958 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 50 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Gene3D G3DSA:3.90.740.10 201 447 1.0E-290 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Gene3D G3DSA:3.40.50.620 7 680 1.0E-290 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 10 681 9.7E-65 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Pfam PF08264 Anticodon-binding domain of tRNA 717 849 7.6E-29 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 SUPERFAMILY SSF50677 207 439 2.44E-32 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 Gene3D G3DSA:1.10.10.720 857 908 4.1E-46 T 23-10-2018 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 SUPERFAMILY SSF47323 706 903 2.24E-37 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0258 7e9925db0a656128ca89233b4e32a3b7 958 SUPERFAMILY SSF52374 2 686 4.93E-98 T 23-10-2018 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 SUPERFAMILY SSF53790 5 262 2.62E-61 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 215 7.6E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 TIGRFAM TIGR00522 dph5: diphthine synthase 7 260 1.3E-103 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 Hamap MF_01084 Diphthine synthase [dphB]. 6 260 35.072 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 Gene3D G3DSA:3.30.950.10 119 268 2.2E-55 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 PIRSF PIRSF036432 6 264 8.7E-99 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TSIB_0124 6fa8711cfe9db427a39995940f9fb1aa 268 Gene3D G3DSA:3.40.1010.10 5 118 3.6E-40 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 SUPERFAMILY SSF53448 223 426 3.13E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 Gene3D G3DSA:3.90.550.10 214 440 5.6E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 SUPERFAMILY SSF56784 4 219 3.74E-31 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 183 1.8E-22 T 23-10-2018 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 Gene3D G3DSA:3.40.50.1000 9 190 1.3E-27 T 23-10-2018 IPR023214 HAD superfamily TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 175 188 2.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 2.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 2.6E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 Gene3D G3DSA:1.10.260.80 19 84 1.3E-27 T 23-10-2018 TSIB_1274 2f2c6334cd407c0a16ad4ef672d50b84 443 Pfam PF00535 Glycosyl transferase family 2 224 349 3.9E-25 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 TIGRFAM TIGR00260 thrC: threonine synthase 48 368 9.7E-105 T 23-10-2018 IPR004450 Threonine synthase-like TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 PIRSF PIRSF038945 19 392 1.3E-150 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 361 5.7E-82 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 Gene3D G3DSA:3.40.50.1100 49 367 1.6E-132 T 23-10-2018 TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 88 101 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 Gene3D G3DSA:3.40.50.1100 96 192 1.6E-132 T 23-10-2018 TSIB_1117 cced9a77ec400a03831c26124b927e2f 392 SUPERFAMILY SSF53686 2 390 2.23E-117 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 SUPERFAMILY SSF51905 109 375 1.24E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 257 1.2E-13 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 1.5E-13 T 23-10-2018 TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Gene3D G3DSA:1.10.10.1100 399 475 4.5E-136 T 23-10-2018 TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Gene3D G3DSA:3.50.50.60 110 481 4.5E-136 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Gene3D G3DSA:3.50.50.60 220 310 4.5E-136 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0635 c9e99ed6150db92b9e54afcaa3325733 494 Gene3D G3DSA:3.10.20.440 1 95 9.0E-38 T 23-10-2018 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 Gene3D G3DSA:3.90.1170.20 10 271 4.5E-93 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 3.3E-97 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 8.9E-50 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 1.1E-31 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 PIRSF PIRSF006250 4 275 6.0E-92 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 SUPERFAMILY SSF54675 5 103 7.46E-32 T 23-10-2018 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 Gene3D G3DSA:3.20.20.70 120 263 4.5E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0053 3a73c980eea913ddf71fc227c5faf4a7 275 SUPERFAMILY SSF51690 104 273 1.88E-48 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSIB_0380 185faf5b0695e4d3fb32bcf176d5cfa1 65 SUPERFAMILY SSF103456 8 62 6.8E-21 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0380 185faf5b0695e4d3fb32bcf176d5cfa1 65 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 8 64 2.8E-20 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0380 185faf5b0695e4d3fb32bcf176d5cfa1 65 Hamap MF_00422 Protein translocase subunit SecE [secE]. 10 64 11.969 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0380 185faf5b0695e4d3fb32bcf176d5cfa1 65 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 15 43 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0380 185faf5b0695e4d3fb32bcf176d5cfa1 65 Gene3D G3DSA:1.20.5.820 5 65 3.3E-25 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0986 ac95fd86f6889a03cc8353f6a5fb2a29 459 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 31 417 2.2E-62 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSIB_0986 ac95fd86f6889a03cc8353f6a5fb2a29 459 Gene3D G3DSA:1.20.1730.10 20 459 1.5E-86 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily TSIB_0986 ac95fd86f6889a03cc8353f6a5fb2a29 459 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 399 419 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site TSIB_0986 ac95fd86f6889a03cc8353f6a5fb2a29 459 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site TSIB_0986 ac95fd86f6889a03cc8353f6a5fb2a29 459 Pfam PF00474 Sodium:solute symporter family 31 417 2.5E-56 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSIB_0684 cfd4e87ae74bbe2178222a9eb1585b75 274 Gene3D G3DSA:3.30.1360.130 112 258 4.4E-74 T 23-10-2018 TSIB_0684 cfd4e87ae74bbe2178222a9eb1585b75 274 Gene3D G3DSA:3.40.50.10780 1 211 4.4E-74 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal TSIB_0684 cfd4e87ae74bbe2178222a9eb1585b75 274 SUPERFAMILY SSF63992 1 269 2.09E-74 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily TSIB_0684 cfd4e87ae74bbe2178222a9eb1585b75 274 PIRSF PIRSF015853 1 271 5.9E-84 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TSIB_0684 cfd4e87ae74bbe2178222a9eb1585b75 274 Pfam PF04951 D-aminopeptidase 1 259 3.5E-79 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TSIB_0329 de3b252053e744ccf3e46d7cfb057738 682 Gene3D G3DSA:3.10.105.10 301 548 1.1E-166 T 23-10-2018 TSIB_0329 de3b252053e744ccf3e46d7cfb057738 682 SUPERFAMILY SSF53850 40 570 6.88E-90 T 23-10-2018 TSIB_0329 de3b252053e744ccf3e46d7cfb057738 682 Gene3D G3DSA:3.90.76.10 71 252 1.1E-166 T 23-10-2018 TSIB_0329 de3b252053e744ccf3e46d7cfb057738 682 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 481 4.7E-65 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TSIB_0329 de3b252053e744ccf3e46d7cfb057738 682 Gene3D G3DSA:3.40.190.10 34 568 1.1E-166 T 23-10-2018 TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 SUPERFAMILY SSF52540 227 553 7.02E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 Gene3D G3DSA:3.40.50.300 405 630 5.6E-28 T 23-10-2018 TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 SMART SM00487 214 412 6.0E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 Pfam PF00271 Helicase conserved C-terminal domain 439 537 2.5E-13 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 SMART SM00490 454 539 1.1E-19 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 Pfam PF00270 DEAD/DEAH box helicase 220 383 1.1E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_1242 72e6456523ae09ecc3b8a8a904771899 834 Gene3D G3DSA:3.40.50.300 200 403 1.8E-50 T 23-10-2018 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 Pfam PF00557 Metallopeptidase family M24 9 291 1.5E-42 T 23-10-2018 IPR000994 Peptidase M24 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 Gene3D G3DSA:1.10.10.10 199 275 1.0E-105 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 81 97 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 PRINTS PR00599 Methionine aminopeptidase-1 signature 56 69 1.7E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 PRINTS PR00599 Methionine aminopeptidase-1 signature 148 160 1.7E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 PRINTS PR00599 Methionine aminopeptidase-1 signature 81 97 1.7E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 PRINTS PR00599 Methionine aminopeptidase-1 signature 180 192 1.7E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 Gene3D G3DSA:3.90.230.10 12 289 1.0E-105 T 23-10-2018 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 SUPERFAMILY SSF46785 199 275 2.18E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 Hamap MF_01975 Methionine aminopeptidase [map]. 7 298 47.613 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 SUPERFAMILY SSF55920 4 298 5.23E-66 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TSIB_1503 210a652c12da1de0f5f3484e1eb39604 298 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 5 298 1.2E-117 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Gene3D G3DSA:3.40.50.300 19 220 8.8E-66 T 23-10-2018 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 PRINTS PR00315 GTP-binding elongation factor signature 119 130 4.8E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 PRINTS PR00315 GTP-binding elongation factor signature 157 166 4.8E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 PRINTS PR00315 GTP-binding elongation factor signature 103 113 4.8E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 PRINTS PR00315 GTP-binding elongation factor signature 29 42 4.8E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 20 426 63.198 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 212 3.7E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Gene3D G3DSA:2.40.30.10 221 335 5.7E-46 T 23-10-2018 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 SUPERFAMILY SSF50465 334 426 3.96E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Pfam PF03144 Elongation factor Tu domain 2 248 328 1.3E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Pfam PF00009 Elongation factor Tu GTP binding domain 28 216 7.3E-31 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 SUPERFAMILY SSF50447 220 333 5.2E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 341 425 3.7E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 24 426 2.2E-210 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 Gene3D G3DSA:2.40.30.10 336 427 1.2E-34 T 23-10-2018 TSIB_0720 6161dc26b770cc3a7933f4867393434e 427 SUPERFAMILY SSF52540 14 228 2.47E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1439 bcc8eab9e68ca00826bae59489674dfd 117 Gene3D G3DSA:3.40.1230.10 1 117 1.1E-36 T 23-10-2018 IPR036748 MTH938-like superfamily TSIB_1439 bcc8eab9e68ca00826bae59489674dfd 117 SUPERFAMILY SSF64076 1 117 1.19E-35 T 23-10-2018 IPR036748 MTH938-like superfamily TSIB_1439 bcc8eab9e68ca00826bae59489674dfd 117 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 2 114 2.6E-13 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 SUPERFAMILY SSF54814 12 74 5.43E-11 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 Gene3D G3DSA:3.30.300.20 74 144 7.1E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 29.6 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 SUPERFAMILY SSF54814 76 141 4.58E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 Pfam PF07650 KH domain 12 98 3.8E-16 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 Gene3D G3DSA:3.30.300.20 2 73 2.3E-26 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0392 28883a07a2fab79fbda99795701ae8e5 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 2.1E-57 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF00136 DNA polymerase family B 1032 1074 6.6E-6 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF00136 DNA polymerase family B 1239 1445 6.8E-30 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF00136 DNA polymerase family B 353 496 4.9E-26 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.30.1490.210 938 990 1.1E-201 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.90.1600.10 1029 1060 1.4E-5 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF51294 1082 1239 2.35E-27 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.90.1600.10 1236 1306 1.6E-7 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1009 1033 4.7E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1217 1239 4.8E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF56672 1031 1456 4.89E-73 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:2.170.16.10 509 1028 1.1E-201 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SMART SM00306 493 618 1.3E-27 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SMART SM00306 1080 1196 7.7E-21 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF51294 495 1033 3.73E-39 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF53098 1 348 4.91E-86 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.90.1600.10 371 485 8.4E-30 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:2.170.16.10 1082 1235 2.3E-29 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1083 1173 8.8E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 508 594 3.2E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 280 2.3E-36 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF03104 DNA polymerase family B, exonuclease domain 32 129 4.7E-10 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF55608 852 940 2.21E-15 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 11 496 6.2E-100 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 1237 1444 7.5E-74 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SMART SM00305 1198 1244 8.3E-11 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SMART SM00305 990 1038 1.8E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.30.420.10 131 349 3.3E-156 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Pfam PF14890 Intein splicing domain 504 1032 2.2E-57 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SMART SM00486 133 551 2.3E-100 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 896 911 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 869 881 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 773 785 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 581 594 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 1233 1242 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 PRINTS PR00379 Intein signature 1007 1024 1.6E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:1.10.132.60 1307 1469 2.4E-57 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:1.10.10.1010 622 768 1.1E-201 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 SUPERFAMILY SSF56672 351 496 2.72E-40 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.30.342.10 4 368 3.3E-156 T 23-10-2018 TSIB_0919 451ae3b071e821981e622dc675c3d87e 1469 Gene3D G3DSA:3.10.28.10 769 937 1.1E-201 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 621 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 642 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 704 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 1.5E-25 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 SUPERFAMILY SSF56784 485 792 2.78E-64 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 66 5.7E-20 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 135 1.8E-12 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Pfam PF00122 E1-E2 ATPase 287 466 5.6E-58 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Pfam PF00403 Heavy-metal-associated domain 4 65 7.7E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Pfam PF00403 Heavy-metal-associated domain 74 135 2.3E-18 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Gene3D G3DSA:2.70.150.20 279 391 2.9E-44 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 794 2.5E-196 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 409 423 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 662 679 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 719 733 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 116 136 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 256 275 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 PRINTS PR00943 Copper-transporting ATPase signature 470 485 6.0E-13 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 765 3.3E-105 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 SUPERFAMILY SSF81665 251 479 2.62E-13 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 SUPERFAMILY SSF81653 290 386 1.7E-30 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 699 1.1E-46 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Gene3D G3DSA:3.40.50.1000 468 737 4.5E-100 T 23-10-2018 IPR023214 HAD superfamily TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Gene3D G3DSA:3.30.70.100 1 66 2.6E-22 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 SUPERFAMILY SSF55008 71 138 1.57E-21 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Gene3D G3DSA:3.30.70.100 69 158 1.4E-23 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 Gene3D G3DSA:3.40.1110.10 498 617 4.5E-100 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 795 4.5E-182 T 23-10-2018 TSIB_1704 aff6dcd741729b83a91dbbed26159e20 799 SUPERFAMILY SSF55008 1 67 2.49E-20 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSIB_1332 b5aadcaaa4de3b7e2a49eea8e04c2732 148 SUPERFAMILY SSF52374 7 140 1.15E-26 T 23-10-2018 TSIB_1332 b5aadcaaa4de3b7e2a49eea8e04c2732 148 Pfam PF01467 Cytidylyltransferase-like 10 140 1.1E-22 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_1332 b5aadcaaa4de3b7e2a49eea8e04c2732 148 Gene3D G3DSA:3.40.50.620 1 146 2.9E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1332 b5aadcaaa4de3b7e2a49eea8e04c2732 148 Hamap MF_02115 FAD synthase [ribL]. 7 147 29.638 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSIB_1332 b5aadcaaa4de3b7e2a49eea8e04c2732 148 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 74 2.7E-19 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_0437 ad5be654e62e9e7c4d9e619e5e50731c 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.757 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 TSIB_0437 ad5be654e62e9e7c4d9e619e5e50731c 118 SUPERFAMILY SSF102462 3 118 4.88E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TSIB_0437 ad5be654e62e9e7c4d9e619e5e50731c 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 4.7E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TSIB_0437 ad5be654e62e9e7c4d9e619e5e50731c 118 Gene3D G3DSA:3.40.1490.10 1 118 3.3E-48 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TSIB_0437 ad5be654e62e9e7c4d9e619e5e50731c 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 6.1E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 SUPERFAMILY SSF81631 150 274 1.8E-34 T 23-10-2018 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 SUPERFAMILY SSF55003 263 443 6.67E-37 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Hamap MF_01264 CCA-adding enzyme [cca]. 1 449 147.171 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 4 413 3.3E-135 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Pfam PF01909 Nucleotidyltransferase domain 36 138 1.4E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 PIRSF PIRSF005335 1 449 9.8E-143 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Gene3D G3DSA:3.30.70.590 284 420 3.3E-23 T 23-10-2018 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Pfam PF09249 tRNA nucleotidyltransferase, second domain 152 273 8.7E-37 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Gene3D G3DSA:3.30.460.10 13 149 1.5E-85 T 23-10-2018 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Gene3D G3DSA:1.10.1410.30 6 273 1.5E-85 T 23-10-2018 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 SUPERFAMILY SSF81301 4 147 4.91E-35 T 23-10-2018 TSIB_1139 19c9c4220501886b7ad658b30ea4ffe5 449 Gene3D G3DSA:3.30.70.1550 354 393 3.3E-23 T 23-10-2018 TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 Gene3D G3DSA:3.40.50.1100 97 193 1.1E-130 T 23-10-2018 TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 PIRSF PIRSF038945 29 390 5.3E-149 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 SUPERFAMILY SSF53686 2 387 1.83E-116 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 TIGRFAM TIGR00260 thrC: threonine synthase 48 367 3.8E-108 T 23-10-2018 IPR004450 Threonine synthase-like TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 360 7.0E-81 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 89 102 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSIB_1600 e95f1fa57c0e79c15e1468b040cede2a 390 Gene3D G3DSA:3.40.50.1100 53 366 1.1E-130 T 23-10-2018 TSIB_1885 12957170f3ba523fcee659952e0f31d2 151 Pfam PF02915 Rubrerythrin 10 145 8.5E-5 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1885 12957170f3ba523fcee659952e0f31d2 151 Gene3D G3DSA:1.20.1260.10 1 148 7.8E-8 T 23-10-2018 IPR012347 Ferritin-like TSIB_1885 12957170f3ba523fcee659952e0f31d2 151 SUPERFAMILY SSF47240 3 150 9.13E-9 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_0068 869e63aa111313676cb93c4046325679 256 SUPERFAMILY SSF109604 50 170 8.79E-9 T 23-10-2018 TSIB_0068 869e63aa111313676cb93c4046325679 256 Gene3D G3DSA:1.10.3210.10 19 198 1.4E-8 T 23-10-2018 TSIB_0068 869e63aa111313676cb93c4046325679 256 SMART SM00471 48 181 0.0014 T 23-10-2018 IPR003607 HD/PDEase domain TSIB_0068 869e63aa111313676cb93c4046325679 256 Pfam PF01966 HD domain 63 171 1.9E-8 T 23-10-2018 IPR006674 HD domain TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 Gene3D G3DSA:3.40.50.261 143 307 1.0E-57 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 168 304 3.7E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 SUPERFAMILY SSF52210 144 306 1.7E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 Gene3D G3DSA:3.40.50.720 9 141 6.3E-43 T 23-10-2018 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 SUPERFAMILY SSF51735 10 142 9.6E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 Gene3D G3DSA:3.40.50.261 308 473 1.0E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 SMART SM00881 13 112 2.4E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 Pfam PF13380 CoA binding domain 17 146 2.3E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0207 04753c1f59bf54c8b55f19573603cd24 473 SUPERFAMILY SSF52210 310 467 1.57E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 SMART SM00846 3 141 2.0E-19 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 Gene3D G3DSA:3.30.360.10 140 301 8.0E-148 T 23-10-2018 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 Gene3D G3DSA:3.40.50.720 3 331 8.0E-148 T 23-10-2018 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 1.6E-31 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 PIRSF PIRSF000149 1 318 8.7E-86 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 3.4E-14 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 SUPERFAMILY SSF51735 3 158 2.31E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 6.1E-181 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 190.414 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TSIB_0949 a40b2629ba0d21543aebffd018539ae5 334 SUPERFAMILY SSF55347 140 301 5.7E-53 T 23-10-2018 TSIB_1378 f0407b9b7109c26ddc7164798e6da009 315 Gene3D G3DSA:3.40.50.970 98 313 9.4E-73 T 23-10-2018 TSIB_1378 f0407b9b7109c26ddc7164798e6da009 315 Gene3D G3DSA:3.40.50.970 12 97 2.0E-11 T 23-10-2018 TSIB_1378 f0407b9b7109c26ddc7164798e6da009 315 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 2.3E-26 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1378 f0407b9b7109c26ddc7164798e6da009 315 SUPERFAMILY SSF52518 12 307 1.3E-79 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_0549 2c1bc213248b67b435018334b8a72c35 417 Gene3D G3DSA:3.40.640.10 81 306 2.2E-162 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0549 2c1bc213248b67b435018334b8a72c35 417 Gene3D G3DSA:3.90.1150.10 36 412 2.2E-162 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0549 2c1bc213248b67b435018334b8a72c35 417 SUPERFAMILY SSF53383 17 415 3.58E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0549 2c1bc213248b67b435018334b8a72c35 417 Pfam PF00155 Aminotransferase class I and II 63 407 1.6E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1920 a52c52000fc6c5894f0c46948ffa1b7f 377 SUPERFAMILY SSF53756 2 365 3.45E-123 T 23-10-2018 TSIB_1920 a52c52000fc6c5894f0c46948ffa1b7f 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 360 1.8E-119 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSIB_1920 a52c52000fc6c5894f0c46948ffa1b7f 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 362 4.1E-133 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TSIB_1920 a52c52000fc6c5894f0c46948ffa1b7f 377 Gene3D G3DSA:3.40.50.2000 183 347 6.3E-135 T 23-10-2018 TSIB_1920 a52c52000fc6c5894f0c46948ffa1b7f 377 Gene3D G3DSA:3.40.50.2000 6 357 6.3E-135 T 23-10-2018 TSIB_0071 cea178778d57f579525c639fb9887cca 213 PIRSF PIRSF019202 1 213 1.2E-47 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TSIB_0071 cea178778d57f579525c639fb9887cca 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.2E-26 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TSIB_1623 64fbeabb977829506dcea6bc4709cf76 348 SUPERFAMILY SSF56059 7 336 1.65E-97 T 23-10-2018 TSIB_1623 64fbeabb977829506dcea6bc4709cf76 348 Gene3D G3DSA:3.30.470.20 198 348 4.1E-46 T 23-10-2018 TSIB_1623 64fbeabb977829506dcea6bc4709cf76 348 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 340 2.1E-113 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSIB_1623 64fbeabb977829506dcea6bc4709cf76 348 Gene3D G3DSA:3.30.1490.20 6 197 7.3E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 Gene3D G3DSA:3.30.70.3130 1 80 8.0E-11 T 23-10-2018 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 Gene3D G3DSA:3.40.50.150 187 383 8.8E-64 T 23-10-2018 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 SUPERFAMILY SSF88697 88 159 1.1E-17 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 167 381 8.2E-65 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 173 187 5.4E-27 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 268 280 5.4E-27 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 381 5.4E-27 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 315 331 5.4E-27 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 202 212 5.4E-27 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 83 158 4.4E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 Gene3D G3DSA:2.30.130.70 81 167 8.0E-19 T 23-10-2018 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 Pfam PF01472 PUA domain 89 158 3.1E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 Pfam PF01189 16S rRNA methyltransferase RsmB/F 192 380 1.1E-57 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 SMART SM00359 89 163 4.5E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1842 311ae5df1f4a931822fbcf9f50b3cd2f 383 SUPERFAMILY SSF53335 5 382 1.03E-57 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 SUPERFAMILY SSF52540 27 351 1.13E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 Pfam PF08494 DEAD/H associated 587 752 4.1E-17 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 Pfam PF00270 DEAD/DEAH box helicase 18 182 7.2E-29 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 SMART SM00487 12 208 9.0E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 Gene3D G3DSA:3.40.50.300 230 379 8.0E-29 T 23-10-2018 TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 Gene3D G3DSA:3.40.50.300 2 199 9.3E-47 T 23-10-2018 TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 SMART SM00490 259 341 3.7E-23 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 PIRSF PIRSF037307 1 915 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TSIB_1455 7873e3884e71085201ac8d7ff3812f26 916 Pfam PF00271 Helicase conserved C-terminal domain 237 336 1.4E-18 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 Gene3D G3DSA:3.30.300.340 20 288 8.3E-170 T 23-10-2018 TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 8 403 2.6E-180 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 7 407 52.128 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 Gene3D G3DSA:3.30.300.10 32 156 8.3E-170 T 23-10-2018 TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 23 407 0.0 T 23-10-2018 TSIB_0975 d391020652bd7b0b763549c4f526ac49 407 Gene3D G3DSA:3.30.300.280 18 400 8.3E-170 T 23-10-2018 TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 SUPERFAMILY SSF89124 128 368 1.31E-79 T 23-10-2018 IPR036070 Nop domain superfamily TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 Gene3D G3DSA:1.10.150.460 163 214 1.9E-36 T 23-10-2018 TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 Pfam PF01798 snoRNA binding domain, fibrillarin 140 365 7.6E-73 T 23-10-2018 IPR002687 Nop domain TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 Gene3D G3DSA:3.30.420.220 1 127 5.8E-51 T 23-10-2018 TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 Gene3D G3DSA:1.10.287.660 133 245 1.9E-36 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 Gene3D G3DSA:1.10.246.90 246 370 3.5E-51 T 23-10-2018 TSIB_0798 143e86db3dd14e65fa8a5887d052b114 416 SMART SM00931 132 184 1.0E-26 T 23-10-2018 IPR012976 NOSIC TSIB_1162 5183563f6fb4ba12929b12d82219d529 104 SUPERFAMILY SSF54913 1 103 4.45E-36 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSIB_1162 5183563f6fb4ba12929b12d82219d529 104 Pfam PF03091 CutA1 divalent ion tolerance protein 5 100 4.1E-32 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TSIB_1162 5183563f6fb4ba12929b12d82219d529 104 Gene3D G3DSA:3.30.70.120 1 103 1.9E-37 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSIB_0869 cf19910d6685602666d0595f71c73e21 813 SUPERFAMILY SSF52540 260 399 8.11E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0869 cf19910d6685602666d0595f71c73e21 813 SUPERFAMILY SSF55729 492 649 3.87E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Pfam PF05127 Helicase 286 460 4.4E-54 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Gene3D G3DSA:3.40.50.12320 282 450 5.2E-33 T 23-10-2018 TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Gene3D G3DSA:3.40.50.11040 105 252 1.1E-11 T 23-10-2018 TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Pfam PF08351 Domain of unknown function (DUF1726) 130 222 1.2E-33 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 809 48.065 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Pfam PF13718 GNAT acetyltransferase 2 501 615 3.5E-34 T 23-10-2018 IPR000182 GNAT domain TSIB_0869 cf19910d6685602666d0595f71c73e21 813 Gene3D G3DSA:3.40.630.30 458 664 1.9E-56 T 23-10-2018 TSIB_1461 c18d534779282c1281f103cc40cbbb55 333 Gene3D G3DSA:3.30.70.2580 3 61 1.1E-5 T 23-10-2018 TSIB_1461 c18d534779282c1281f103cc40cbbb55 333 Gene3D G3DSA:3.30.300.110 62 145 6.2E-29 T 23-10-2018 TSIB_1461 c18d534779282c1281f103cc40cbbb55 333 SUPERFAMILY SSF53335 75 332 8.81E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1461 c18d534779282c1281f103cc40cbbb55 333 Gene3D G3DSA:3.40.50.150 146 333 2.3E-56 T 23-10-2018 TSIB_1461 c18d534779282c1281f103cc40cbbb55 333 Pfam PF02475 Met-10+ like-protein 85 280 1.3E-70 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 Gene3D G3DSA:2.40.50.100 268 339 1.9E-28 T 23-10-2018 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 Gene3D G3DSA:2.40.50.140 248 343 1.9E-28 T 23-10-2018 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 Pfam PF03459 TOBE domain 281 343 1.4E-15 T 23-10-2018 IPR005116 Transport-associated OB, type 1 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 SUPERFAMILY SSF52540 1 237 2.4E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 280 343 1.4E-19 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 SUPERFAMILY SSF50331 255 344 6.68E-22 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 SMART SM00382 25 271 6.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 Pfam PF00005 ABC transporter 16 159 2.2E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0163 2383807db836fcb901193ad6f55cf12d 344 Gene3D G3DSA:3.40.50.300 1 234 2.1E-69 T 23-10-2018 TSIB_1546 4d80a4d62da98f2769920fa340992f59 157 Pfam PF01967 MoaC family 17 155 7.6E-51 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1546 4d80a4d62da98f2769920fa340992f59 157 Gene3D G3DSA:3.30.70.640 4 157 2.2E-66 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1546 4d80a4d62da98f2769920fa340992f59 157 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 141 3.1E-54 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1546 4d80a4d62da98f2769920fa340992f59 157 SUPERFAMILY SSF55040 15 155 1.19E-49 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1546 4d80a4d62da98f2769920fa340992f59 157 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 12 157 38.775 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 83 91 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 Pfam PF01177 Asp/Glu/Hydantoin racemase 11 224 5.8E-67 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 TIGRFAM TIGR00035 asp_race: aspartate racemase 4 230 8.3E-107 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 Gene3D G3DSA:3.40.50.1860 109 216 2.2E-89 T 23-10-2018 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 Gene3D G3DSA:3.40.50.1860 8 222 2.2E-89 T 23-10-2018 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 SUPERFAMILY SSF53681 121 229 6.21E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_0542 cf54ab4c9425f51feb6d866ce82512ee 231 SUPERFAMILY SSF53681 6 119 3.11E-38 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_0562 6e36df6c4ddad727bdaf138148bc837e 119 Gene3D G3DSA:3.30.70.920 37 115 1.9E-8 T 23-10-2018 TSIB_0562 6e36df6c4ddad727bdaf138148bc837e 119 SMART SM00344 1 92 0.0081 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_0562 6e36df6c4ddad727bdaf138148bc837e 119 Pfam PF01037 Lrp/AsnC ligand binding domain 48 108 5.6E-6 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_0562 6e36df6c4ddad727bdaf138148bc837e 119 SUPERFAMILY SSF54909 45 110 4.02E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0160 b23166c9c8be4dd80cd55ef67e7c09d6 434 SUPERFAMILY SSF52540 130 323 7.59E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0160 b23166c9c8be4dd80cd55ef67e7c09d6 434 PIRSF PIRSF009445 1 433 1.3E-199 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TSIB_0160 b23166c9c8be4dd80cd55ef67e7c09d6 434 Gene3D G3DSA:3.40.50.300 179 323 3.2E-8 T 23-10-2018 TSIB_0160 b23166c9c8be4dd80cd55ef67e7c09d6 434 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 434 50.191 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 Pfam PF01637 ATPase domain predominantly from Archaea 4 195 3.6E-29 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 Gene3D G3DSA:3.40.50.300 57 160 6.4E-17 T 23-10-2018 TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 SUPERFAMILY SSF46785 225 346 1.23E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 SUPERFAMILY SSF52540 3 232 3.38E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 Pfam PF03008 Archaea bacterial proteins of unknown function 300 397 1.1E-29 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TSIB_0959 de467a3b95c9ac607842f0f44f7b5351 446 Gene3D G3DSA:1.10.10.10 225 300 2.9E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1597 375ff192b66028463ece05655b844db9 196 Gene3D G3DSA:3.40.50.300 2 147 6.0E-47 T 23-10-2018 TSIB_1597 375ff192b66028463ece05655b844db9 196 PIRSF PIRSF035805 6 196 5.0E-65 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSIB_1597 375ff192b66028463ece05655b844db9 196 Pfam PF00265 Thymidine kinase 10 193 1.7E-53 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSIB_1597 375ff192b66028463ece05655b844db9 196 SUPERFAMILY SSF57716 148 195 4.28E-16 T 23-10-2018 TSIB_1597 375ff192b66028463ece05655b844db9 196 Hamap MF_00124 Thymidine kinase [tdk]. 8 196 36.081 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSIB_1597 375ff192b66028463ece05655b844db9 196 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 180 193 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSIB_1597 375ff192b66028463ece05655b844db9 196 Gene3D G3DSA:3.30.60.20 148 196 1.2E-23 T 23-10-2018 TSIB_1597 375ff192b66028463ece05655b844db9 196 SUPERFAMILY SSF52540 9 147 1.03E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0423 ea2f7feac4ab11a2ab4d41dbad15a242 126 Pfam PF01751 Toprim domain 51 88 1.3E-5 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0423 ea2f7feac4ab11a2ab4d41dbad15a242 126 SMART SM00493 20 90 7.5E-4 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0423 ea2f7feac4ab11a2ab4d41dbad15a242 126 Gene3D G3DSA:3.40.1360.10 3 117 3.9E-25 T 23-10-2018 TSIB_0423 ea2f7feac4ab11a2ab4d41dbad15a242 126 SUPERFAMILY SSF110455 19 101 2.62E-7 T 23-10-2018 TSIB_0423 ea2f7feac4ab11a2ab4d41dbad15a242 126 Hamap MF_01095 UPF0292 protein . 3 123 35.689 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 SUPERFAMILY SSF51306 42 153 1.26E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 10 160 5.8E-37 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 ProSitePatterns PS00501 Signal peptidases I serine active site. 46 53 - T 23-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 Pfam PF00717 Peptidase S24-like 44 92 3.9E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 44 59 1.1E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_1179 b9eac88369d5a9b9c73330344f03e569 170 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 102 113 1.1E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_0728 5f9eb53d2692d233c085b960268ce8a3 333 SUPERFAMILY SSF50891 173 288 9.48E-12 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TSIB_0728 5f9eb53d2692d233c085b960268ce8a3 333 SMART SM00797 23 299 9.6E-142 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSIB_0728 5f9eb53d2692d233c085b960268ce8a3 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 305 2.0E-115 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSIB_0728 5f9eb53d2692d233c085b960268ce8a3 333 Gene3D G3DSA:2.40.100.10 170 310 3.1E-50 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TSIB_0728 5f9eb53d2692d233c085b960268ce8a3 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 282 6.3E-87 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSIB_0443 63ea87683b3e316f323381b79235478c 421 ProSitePatterns PS00482 Dihydroorotase signature 1. 53 61 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSIB_0443 63ea87683b3e316f323381b79235478c 421 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 416 1.6E-122 T 23-10-2018 TSIB_0443 63ea87683b3e316f323381b79235478c 421 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 417 40.312 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSIB_0443 63ea87683b3e316f323381b79235478c 421 Gene3D G3DSA:3.20.20.140 51 361 6.0E-128 T 23-10-2018 TSIB_0443 63ea87683b3e316f323381b79235478c 421 SUPERFAMILY SSF51556 50 357 6.31E-92 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_0443 63ea87683b3e316f323381b79235478c 421 Pfam PF01979 Amidohydrolase family 46 414 1.6E-34 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSIB_0443 63ea87683b3e316f323381b79235478c 421 SUPERFAMILY SSF51338 2 419 1.27E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_0443 63ea87683b3e316f323381b79235478c 421 Gene3D G3DSA:2.30.40.10 11 414 6.0E-128 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_1401 2838b78a73eef8a63ac96e797f427cb5 322 Gene3D G3DSA:3.40.50.300 46 254 2.8E-89 T 23-10-2018 TSIB_1401 2838b78a73eef8a63ac96e797f427cb5 322 Pfam PF03308 ArgK protein 21 286 9.6E-103 T 23-10-2018 TSIB_1401 2838b78a73eef8a63ac96e797f427cb5 322 SMART SM00382 47 197 1.9E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1401 2838b78a73eef8a63ac96e797f427cb5 322 SUPERFAMILY SSF52540 4 314 1.26E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1401 2838b78a73eef8a63ac96e797f427cb5 322 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 315 9.9E-128 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSIB_0501 aa3147b83ccc3819e98e5d9e4b7b77c3 80 Gene3D G3DSA:2.30.30.90 6 80 5.2E-21 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain TSIB_0501 aa3147b83ccc3819e98e5d9e4b7b77c3 80 Pfam PF04023 FeoA domain 7 78 1.4E-20 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSIB_0501 aa3147b83ccc3819e98e5d9e4b7b77c3 80 SUPERFAMILY SSF50037 9 77 2.98E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TSIB_0501 aa3147b83ccc3819e98e5d9e4b7b77c3 80 SMART SM00899 7 78 1.3E-18 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSIB_0433 0f56f02c2841ec4a41493fcad3d8af1b 207 Pfam PF01966 HD domain 38 138 1.2E-18 T 23-10-2018 IPR006674 HD domain TSIB_0433 0f56f02c2841ec4a41493fcad3d8af1b 207 Gene3D G3DSA:1.10.3210.50 16 207 2.9E-58 T 23-10-2018 TSIB_0433 0f56f02c2841ec4a41493fcad3d8af1b 207 SMART SM00471 33 148 5.0E-11 T 23-10-2018 IPR003607 HD/PDEase domain TSIB_0433 0f56f02c2841ec4a41493fcad3d8af1b 207 SUPERFAMILY SSF109604 17 206 2.69E-54 T 23-10-2018 TSIB_0433 0f56f02c2841ec4a41493fcad3d8af1b 207 TIGRFAM TIGR00277 HDIG: HDIG domain 37 103 3.6E-9 T 23-10-2018 IPR006675 HDIG domain TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 Gene3D G3DSA:3.30.470.20 125 382 3.9E-92 T 23-10-2018 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 Pfam PF06973 Domain of unknown function (DUF1297) 192 383 1.2E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 Pfam PF06849 Protein of unknown function (DUF1246) 24 156 6.3E-44 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 PIRSF PIRSF004602 4 383 5.3E-145 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 Gene3D G3DSA:3.30.1490.20 155 221 3.9E-92 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 Gene3D G3DSA:3.40.50.20 4 124 5.9E-43 T 23-10-2018 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 SUPERFAMILY SSF56059 142 383 1.12E-76 T 23-10-2018 TSIB_0059 c075c19b16c0dd91260fca3f9cac92bb 383 SUPERFAMILY SSF52440 4 136 2.88E-42 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 322.885 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Pfam PF02938 GAD domain 299 390 2.1E-16 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 SMART SM00845 484 624 2.3E-35 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 SUPERFAMILY SSF55931 4 453 1.44E-98 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Gene3D G3DSA:1.10.10.410 566 624 1.1E-11 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 SUPERFAMILY SSF55261 279 404 1.32E-44 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Gene3D G3DSA:1.10.150.380 453 545 8.2E-22 T 23-10-2018 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 SUPERFAMILY SSF89095 482 624 8.5E-27 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Pfam PF02637 GatB domain 485 624 2.6E-26 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Gene3D G3DSA:3.30.1360.30 274 404 9.5E-52 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 7.0E-45 T 23-10-2018 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 Pfam PF02934 GatB/GatE catalytic domain 13 444 8.7E-65 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TSIB_0609 6ba066e01d11d04c474dcfaf6caa1f84 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 626 3.5E-236 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 Gene3D G3DSA:1.10.10.10 5 78 5.0E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 SUPERFAMILY SSF46785 6 82 1.41E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 Pfam PF12802 MarR family 7 65 3.1E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 SMART SM00419 21 72 1.2E-9 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 Pfam PF01037 Lrp/AsnC ligand binding domain 88 153 7.8E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 Gene3D G3DSA:3.30.70.920 79 154 3.0E-10 T 23-10-2018 TSIB_0713 656dcb668cfda5b1d3f79f2e893485f2 154 SUPERFAMILY SSF54909 85 153 1.74E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 SUPERFAMILY SSF53271 69 277 1.43E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 Pfam PF00156 Phosphoribosyl transferase domain 147 246 2.4E-17 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 Gene3D G3DSA:3.40.50.2020 3 150 1.6E-37 T 23-10-2018 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 SMART SM01400 3 120 6.3E-33 T 23-10-2018 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 116 1.6E-22 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 Gene3D G3DSA:3.40.50.2020 151 278 7.8E-40 T 23-10-2018 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 281 3.0E-89 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSIB_0113 ba7f25c77fb02e4ca18dd9c36bf23af8 286 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 4 285 35.322 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 308 320 6.4E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 210 226 6.4E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 Pfam PF00557 Metallopeptidase family M24 139 338 1.7E-68 T 23-10-2018 IPR000994 Peptidase M24 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 13 131 5.4E-17 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 SUPERFAMILY SSF55920 130 354 1.16E-76 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 Gene3D G3DSA:3.40.350.10 3 129 6.0E-28 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 Gene3D G3DSA:3.90.230.10 132 356 5.7E-84 T 23-10-2018 TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 SUPERFAMILY SSF53092 1 129 1.74E-14 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_0407 9c076991bedfec94a2139575ce0836a1 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 19.95 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 1.0E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 77 1.1E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 Gene3D G3DSA:3.30.1280.10 1 80 9.1E-28 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 1.9E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0058 844e692633fa6881d33ab0658c55fe75 81 SUPERFAMILY SSF82697 3 78 1.92E-24 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 SUPERFAMILY SSF54862 565 620 3.91E-14 T 23-10-2018 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 573 584 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 253 427 7.0E-43 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Pfam PF01472 PUA domain 133 204 1.5E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 SUPERFAMILY SSF52402 223 414 2.43E-43 T 23-10-2018 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 SUPERFAMILY SSF88697 131 204 4.09E-15 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Gene3D G3DSA:2.30.130.10 129 208 4.8E-14 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Pfam PF12838 4Fe-4S dicluster domain 573 615 3.2E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1096 45e035df2959434f78aade4dc04664eb 628 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 121 204 6.5E-12 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Gene3D G3DSA:3.30.70.20 565 619 4.8E-12 T 23-10-2018 TSIB_1096 45e035df2959434f78aade4dc04664eb 628 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 604 615 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1096 45e035df2959434f78aade4dc04664eb 628 Gene3D G3DSA:3.40.50.620 218 439 5.2E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1096 45e035df2959434f78aade4dc04664eb 628 SMART SM00359 132 207 1.2E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 Gene3D G3DSA:3.60.20.10 5 437 5.5E-143 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 SUPERFAMILY SSF56235 5 239 2.83E-54 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 SUPERFAMILY SSF53271 232 438 2.36E-68 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 436 44.405 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 437 1.7E-157 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 PIRSF PIRSF000485 1 441 5.1E-158 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 Pfam PF00156 Phosphoribosyl transferase domain 320 368 3.2E-8 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 Gene3D G3DSA:3.40.50.2020 257 421 5.5E-143 T 23-10-2018 TSIB_0066 b0ef1f5d67cc0440497cb53590a05454 443 Pfam PF13537 Glutamine amidotransferase domain 72 199 6.2E-19 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSIB_1961 57a0e527bf04d6cc77bb7a17ebd12c16 357 Pfam PF01926 50S ribosome-binding GTPase 109 164 8.3E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1961 57a0e527bf04d6cc77bb7a17ebd12c16 357 Gene3D G3DSA:1.10.1580.10 171 254 9.0E-15 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily TSIB_1961 57a0e527bf04d6cc77bb7a17ebd12c16 357 SUPERFAMILY SSF52540 4 170 8.26E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1961 57a0e527bf04d6cc77bb7a17ebd12c16 357 Gene3D G3DSA:3.40.50.300 5 164 8.8E-43 T 23-10-2018 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 SUPERFAMILY SSF46767 91 170 1.12E-22 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 170 3.5E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 97 2.0E-19 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 SUPERFAMILY SSF53155 1 89 2.35E-26 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 Pfam PF09153 Domain of unknown function (DUF1938) 1 86 2.5E-31 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 168 1.7E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 Gene3D G3DSA:3.30.160.70 1 89 4.3E-19 T 23-10-2018 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSIB_1021 7046f392be0feedf83a89d0cbfdd58fd 175 Gene3D G3DSA:1.10.10.10 90 175 3.6E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0137 da35480c5753a3087860c529634c2b37 332 SUPERFAMILY SSF53187 2 331 1.76E-55 T 23-10-2018 TSIB_0137 da35480c5753a3087860c529634c2b37 332 Gene3D G3DSA:3.40.630.10 8 324 1.1E-114 T 23-10-2018 TSIB_0137 da35480c5753a3087860c529634c2b37 332 Gene3D G3DSA:2.40.30.40 64 155 1.1E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TSIB_0137 da35480c5753a3087860c529634c2b37 332 SUPERFAMILY SSF101821 65 172 3.51E-23 T 23-10-2018 TSIB_0137 da35480c5753a3087860c529634c2b37 332 PIRSF PIRSF001123 1 332 2.9E-91 T 23-10-2018 IPR008007 Peptidase M42 TSIB_0137 da35480c5753a3087860c529634c2b37 332 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 1.5E-88 T 23-10-2018 IPR008007 Peptidase M42 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 Gene3D G3DSA:1.10.8.160 174 275 1.6E-123 T 23-10-2018 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 Pfam PF01896 DNA primase small subunit 96 304 4.4E-15 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 Gene3D G3DSA:3.90.920.10 9 324 1.6E-123 T 23-10-2018 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 SUPERFAMILY SSF56747 7 339 8.28E-93 T 23-10-2018 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 341 23.051 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 TSIB_1766 d4b88d3c1249618b98deda21d6099af6 342 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 327 1.3E-59 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TSIB_0921 781715010aeb8736b04948e162200366 744 Pfam PF00271 Helicase conserved C-terminal domain 257 396 7.1E-10 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0921 781715010aeb8736b04948e162200366 744 SMART SM00487 43 231 2.9E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0921 781715010aeb8736b04948e162200366 744 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 32 723 29.815 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 TSIB_0921 781715010aeb8736b04948e162200366 744 SMART SM00490 311 397 4.3E-16 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0921 781715010aeb8736b04948e162200366 744 SMART SM00278 701 720 0.88 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSIB_0921 781715010aeb8736b04948e162200366 744 SMART SM00278 668 687 3.5 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSIB_0921 781715010aeb8736b04948e162200366 744 SUPERFAMILY SSF52540 59 410 6.69E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0921 781715010aeb8736b04948e162200366 744 Gene3D G3DSA:1.10.3380.30 434 664 7.2E-69 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 SUPERFAMILY SSF158702 516 724 1.67E-55 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 SUPERFAMILY SSF46785 428 515 5.71E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0921 781715010aeb8736b04948e162200366 744 Gene3D G3DSA:1.10.150.20 666 722 5.8E-20 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 Pfam PF14520 Helix-hairpin-helix domain 669 718 1.9E-8 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 Gene3D G3DSA:3.40.50.300 31 223 1.1E-71 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 Gene3D G3DSA:3.40.50.300 224 422 4.6E-62 T 23-10-2018 TSIB_0921 781715010aeb8736b04948e162200366 744 Pfam PF00270 DEAD/DEAH box helicase 51 203 1.6E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_0218 52e54f36c07d553cad61f4a82a838c51 685 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 664 683 9.9E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TSIB_0218 52e54f36c07d553cad61f4a82a838c51 685 SUPERFAMILY SSF56300 123 415 1.2E-32 T 23-10-2018 TSIB_0218 52e54f36c07d553cad61f4a82a838c51 685 Pfam PF00149 Calcineurin-like phosphoesterase 123 361 5.8E-13 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_0218 52e54f36c07d553cad61f4a82a838c51 685 Gene3D G3DSA:3.60.21.10 177 370 2.3E-21 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 8 256 1.6E-70 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 194 210 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 SUPERFAMILY SSF51556 7 258 1.11E-53 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 Gene3D G3DSA:3.20.20.140 5 258 1.4E-62 T 23-10-2018 TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 Pfam PF01026 TatD related DNase 9 255 2.1E-54 T 23-10-2018 IPR001130 TatD family GO:0016788 TSIB_1444 d5f04ceed6f24daec0571dda13f9ab91 260 PIRSF PIRSF005902 4 259 3.2E-59 T 23-10-2018 IPR001130 TatD family GO:0016788 TSIB_0574 bbe64917ec75aa5f61d0973d8d720a37 65 Pfam PF01667 Ribosomal protein S27 11 64 1.8E-24 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0574 bbe64917ec75aa5f61d0973d8d720a37 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 21.298 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0574 bbe64917ec75aa5f61d0973d8d720a37 65 Gene3D G3DSA:2.20.25.100 11 65 3.1E-23 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily TSIB_0574 bbe64917ec75aa5f61d0973d8d720a37 65 SUPERFAMILY SSF57829 11 65 1.37E-17 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSIB_0574 bbe64917ec75aa5f61d0973d8d720a37 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1431 f7f3e4539b0069af5ce24412f4943c60 75 SUPERFAMILY SSF54285 7 75 5.09E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_1431 f7f3e4539b0069af5ce24412f4943c60 75 Pfam PF02597 ThiS family 18 75 2.7E-10 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1431 f7f3e4539b0069af5ce24412f4943c60 75 Gene3D G3DSA:3.10.20.30 2 75 6.6E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1728 11396696c634932ad59c750516e8b25b 459 Pfam PF01554 MatE 26 186 4.0E-33 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1728 11396696c634932ad59c750516e8b25b 459 Pfam PF01554 MatE 248 413 5.2E-25 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1728 11396696c634932ad59c750516e8b25b 459 PIRSF PIRSF006603 1 458 1.9E-97 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1728 11396696c634932ad59c750516e8b25b 459 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 426 6.9E-81 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1308 ca8290c2a9c6cbc5111691e2b5891060 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 38 89 1.2E-20 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSIB_0495 b9cef3402ab2c5d9f725f8177f78325d 129 Gene3D G3DSA:1.10.1520.20 2 129 9.2E-43 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal TSIB_0495 b9cef3402ab2c5d9f725f8177f78325d 129 Pfam PF11469 Ribonuclease III 11 128 9.5E-55 T 23-10-2018 IPR021568 Ribonuclease III, archaeal TSIB_0495 b9cef3402ab2c5d9f725f8177f78325d 129 SUPERFAMILY SSF69065 8 128 1.54E-41 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TSIB_0721 967a51363713a54d38d1b806d38823df 146 SUPERFAMILY SSF88723 15 139 3.14E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0721 967a51363713a54d38d1b806d38823df 146 SMART SM00670 15 121 4.3E-7 T 23-10-2018 IPR002716 PIN domain TSIB_0721 967a51363713a54d38d1b806d38823df 146 Pfam PF04900 Fcf1 41 138 1.5E-6 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 TSIB_0721 967a51363713a54d38d1b806d38823df 146 Gene3D G3DSA:3.40.50.1010 14 144 2.0E-27 T 23-10-2018 TSIB_1190 04af5a94566711191110888d58d00e63 154 Gene3D G3DSA:3.30.1440.10 5 153 8.1E-47 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1190 04af5a94566711191110888d58d00e63 154 Pfam PF01877 RNA binding 11 134 5.0E-40 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TSIB_1190 04af5a94566711191110888d58d00e63 154 SUPERFAMILY SSF55282 10 152 1.03E-44 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_2020 338ebdde6615cf7dbfe32ffbf6782965 385 SUPERFAMILY SSF53756 76 377 1.95E-18 T 23-10-2018 TSIB_2020 338ebdde6615cf7dbfe32ffbf6782965 385 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 15 378 1.0E-83 T 23-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 TSIB_2020 338ebdde6615cf7dbfe32ffbf6782965 385 Gene3D G3DSA:3.40.50.12580 176 365 1.9E-73 T 23-10-2018 TSIB_2020 338ebdde6615cf7dbfe32ffbf6782965 385 Gene3D G3DSA:3.40.50.11820 29 372 1.9E-73 T 23-10-2018 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 Gene3D G3DSA:3.60.9.10 7 215 1.1E-83 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 SUPERFAMILY SSF56228 8 213 1.27E-71 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 Gene3D G3DSA:1.10.599.10 439 621 1.4E-88 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 SUPERFAMILY SSF48310 217 633 4.32E-80 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 226 621 1.5E-90 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 SMART SM00790 9 211 2.2E-106 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 11 210 2.8E-77 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1626 a91f7aa844a3458f072a1190f413b3d8 639 Gene3D G3DSA:1.10.569.10 246 438 1.4E-88 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1326 1247e6688d2544ced46fa5d2c035161c 349 Gene3D G3DSA:3.90.1150.10 24 336 7.6E-74 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1326 1247e6688d2544ced46fa5d2c035161c 349 SUPERFAMILY SSF53383 16 340 1.99E-65 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1326 1247e6688d2544ced46fa5d2c035161c 349 Pfam PF00155 Aminotransferase class I and II 34 344 1.5E-50 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1326 1247e6688d2544ced46fa5d2c035161c 349 Gene3D G3DSA:3.40.640.10 34 258 7.6E-74 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1326 1247e6688d2544ced46fa5d2c035161c 349 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 209 222 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 37 438 5.6E-195 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 PIRSF PIRSF500175 18 442 2.7E-187 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 102 110 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 97 434 2.2E-145 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 24 438 48.616 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 Gene3D G3DSA:3.40.50.40 307 444 2.7E-58 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 SMART SM00870 99 422 1.6E-146 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 SUPERFAMILY SSF53774 92 441 3.14E-117 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 Gene3D G3DSA:2.30.30.520 7 84 3.6E-21 T 23-10-2018 IPR037222 GatD, N-terminal TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 177 187 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 Pfam PF00710 Asparaginase, N-terminal 99 293 5.2E-60 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 Gene3D G3DSA:3.40.50.1170 85 306 2.2E-84 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 PRINTS PR00139 Asparaginase/glutaminase family signature 176 194 5.2E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 PRINTS PR00139 Asparaginase/glutaminase family signature 100 111 5.2E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 PRINTS PR00139 Asparaginase/glutaminase family signature 359 377 5.2E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 PIRSF PIRSF001220 94 433 2.1E-109 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0608 0a490b29eded6d763965a7f0bc7572b7 444 SUPERFAMILY SSF141300 11 81 1.83E-17 T 23-10-2018 IPR037222 GatD, N-terminal TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 94 1.7E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 Gene3D G3DSA:3.30.1330.30 1 100 5.6E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 1 98 28.862 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 69 89 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 13 37 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0391 62845ca8794e9833c9b07a65551f80be 100 SUPERFAMILY SSF55315 1 95 6.06E-26 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Gene3D G3DSA:3.40.50.300 96 289 2.5E-120 T 23-10-2018 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Pfam PF00448 SRP54-type protein, GTPase domain 105 300 9.8E-75 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SUPERFAMILY SSF52540 103 302 8.32E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 11 443 37.426 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Gene3D G3DSA:1.20.120.140 11 310 2.5E-120 T 23-10-2018 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SMART SM00963 7 92 3.3E-24 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SUPERFAMILY SSF47364 5 98 6.28E-24 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 273 286 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Pfam PF02978 Signal peptide binding domain 332 430 1.4E-33 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SUPERFAMILY SSF47446 302 434 6.93E-42 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SMART SM00382 104 278 3.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Pfam PF02881 SRP54-type protein, helical bundle domain 11 88 9.2E-20 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 SMART SM00962 105 300 1.0E-97 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 Gene3D G3DSA:1.10.260.30 315 448 2.7E-49 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_1424 b7562710247f0af4f71fc2627e4aab91 453 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 23-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSIB_0985 eafd6dd6e7bd1114a4649585d46dfbf1 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSIB_0985 eafd6dd6e7bd1114a4649585d46dfbf1 391 SUPERFAMILY SSF53383 8 387 2.5E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0985 eafd6dd6e7bd1114a4649585d46dfbf1 391 Gene3D G3DSA:3.90.1150.10 32 384 3.7E-129 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0985 eafd6dd6e7bd1114a4649585d46dfbf1 391 Pfam PF00155 Aminotransferase class I and II 33 383 7.6E-71 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_0985 eafd6dd6e7bd1114a4649585d46dfbf1 391 Gene3D G3DSA:3.40.640.10 52 290 3.7E-129 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0432 40274d153afce1393f1f9e40048402f7 269 Gene3D G3DSA:3.90.1640.20 1 269 1.6E-96 T 23-10-2018 TSIB_0432 40274d153afce1393f1f9e40048402f7 269 Pfam PF14336 Domain of unknown function (DUF4392) 5 260 2.3E-65 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 Pfam PF00361 Proton-conducting membrane transporter 138 441 7.6E-51 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 4.5E-10 T 23-10-2018 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 4.5E-10 T 23-10-2018 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 4.5E-10 T 23-10-2018 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 4.5E-10 T 23-10-2018 TSIB_1288 f026e3c387d564f67230ac9c15a4c828 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 4.5E-10 T 23-10-2018 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 78 110 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 146 212 1.0E-20 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 SUPERFAMILY SSF54211 139 212 6.83E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 9 213 47.319 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 11 222 6.2E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 SUPERFAMILY SSF54768 62 126 7.95E-19 T 23-10-2018 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 Gene3D G3DSA:3.30.160.770 13 123 8.4E-38 T 23-10-2018 TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 Gene3D G3DSA:3.30.230.10 124 217 4.9E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_0309 04680b3f73f08fba032e84d8bedc1c8a 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 63 124 2.1E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSIB_1343 e71d978160883db36db15966c362285f 210 Gene3D G3DSA:3.40.50.10480 1 186 8.4E-33 T 23-10-2018 TSIB_1343 e71d978160883db36db15966c362285f 210 SUPERFAMILY SSF52954 1 193 7.55E-33 T 23-10-2018 TSIB_1343 e71d978160883db36db15966c362285f 210 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 28.54 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein TSIB_1343 e71d978160883db36db15966c362285f 210 SMART SM00879 3 190 4.5E-15 T 23-10-2018 IPR007109 Brix domain TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 SUPERFAMILY SSF51735 21 213 2.14E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 SUPERFAMILY SSF48179 220 314 1.07E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 Gene3D G3DSA:3.40.50.720 6 217 3.6E-59 T 23-10-2018 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 21 199 1.3E-40 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 SMART SM00984 335 431 2.8E-33 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 Gene3D G3DSA:3.40.50.720 219 449 8.8E-68 T 23-10-2018 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 PIRSF PIRSF000124 20 446 3.9E-76 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 21 427 1.3E-133 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 PIRSF PIRSF500136 10 447 6.5E-146 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 SUPERFAMILY SSF52413 322 442 5.23E-31 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 335 430 1.1E-24 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_2032 94ff316ae3087ee6f5e1d73c4509e08d 449 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 308 3.3E-21 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSIB_1044 3c317aa0efe67da229fc73b5f70ba266 231 SUPERFAMILY SSF109755 29 228 2.93E-19 T 23-10-2018 TSIB_1044 3c317aa0efe67da229fc73b5f70ba266 231 Pfam PF01865 Protein of unknown function DUF47 9 229 2.7E-46 T 23-10-2018 IPR018445 Putative phosphate transport regulator TSIB_1044 3c317aa0efe67da229fc73b5f70ba266 231 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 4 229 2.1E-35 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TSIB_1044 3c317aa0efe67da229fc73b5f70ba266 231 Gene3D G3DSA:1.20.58.220 3 231 9.0E-54 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_1199 80d356576285ec4580b92573c6c23a45 94 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 4 93 27.789 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 Pfam PF01918 Alba 9 69 2.4E-20 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 PIRSF PIRSF028732 4 94 1.6E-39 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 Gene3D G3DSA:3.30.110.20 5 93 3.3E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 11 93 2.0E-40 T 23-10-2018 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 SUPERFAMILY SSF82704 8 93 1.03E-26 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TSIB_1199 80d356576285ec4580b92573c6c23a45 94 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 7 93 3.5E-45 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TSIB_1205 7606cce0578c6af5476789ef387fd614 409 Pfam PF07690 Major Facilitator Superfamily 12 357 4.7E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_1205 7606cce0578c6af5476789ef387fd614 409 Gene3D G3DSA:1.20.1250.20 2 390 1.7E-34 T 23-10-2018 TSIB_1205 7606cce0578c6af5476789ef387fd614 409 SUPERFAMILY SSF103473 3 396 2.35E-38 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1205 7606cce0578c6af5476789ef387fd614 409 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 6 367 6.3E-96 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 TSIB_1833 edb7abce2b21bef47a2c9e8ae0baf2cc 248 Pfam PF01972 Serine dehydrogenase proteinase 2 245 4.9E-142 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TSIB_1833 edb7abce2b21bef47a2c9e8ae0baf2cc 248 SUPERFAMILY SSF52096 30 208 9.76E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSIB_1833 edb7abce2b21bef47a2c9e8ae0baf2cc 248 Gene3D G3DSA:3.90.226.10 30 215 1.6E-23 T 23-10-2018 TSIB_1384 c82b743674817f2f7dd4789251d57bb2 186 SUPERFAMILY SSF53323 1 181 4.05E-58 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1384 c82b743674817f2f7dd4789251d57bb2 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 179 2.6E-44 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_1384 c82b743674817f2f7dd4789251d57bb2 186 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 181 2.8E-79 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TSIB_1384 c82b743674817f2f7dd4789251d57bb2 186 Gene3D G3DSA:3.40.920.10 1 183 6.7E-72 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 Gene3D G3DSA:1.10.260.40 10 67 2.1E-16 T 23-10-2018 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 Pfam PF00571 CBS domain 135 184 1.5E-6 T 23-10-2018 IPR000644 CBS domain TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 Pfam PF00571 CBS domain 70 122 1.5E-9 T 23-10-2018 IPR000644 CBS domain TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 PIRSF PIRSF037253 2 186 5.8E-74 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 SMART SM00530 12 66 1.8E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 SMART SM00116 141 186 40.0 T 23-10-2018 IPR000644 CBS domain TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 SMART SM00116 77 124 3.0E-4 T 23-10-2018 IPR000644 CBS domain TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 SUPERFAMILY SSF54631 66 184 3.79E-24 T 23-10-2018 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 Pfam PF01381 Helix-turn-helix 13 61 1.7E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 SUPERFAMILY SSF47413 11 61 1.77E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_0864 0a6fb96f8740f7668a0bd90df0e8b2ab 186 Gene3D G3DSA:3.10.580.10 68 186 1.5E-24 T 23-10-2018 TSIB_1752 8eedb680676637987f36839f75da35c1 813 Gene3D G3DSA:3.10.105.10 427 633 8.3E-12 T 23-10-2018 TSIB_1752 8eedb680676637987f36839f75da35c1 813 Gene3D G3DSA:3.40.190.10 257 411 4.8E-10 T 23-10-2018 TSIB_1752 8eedb680676637987f36839f75da35c1 813 SUPERFAMILY SSF53850 134 610 3.44E-22 T 23-10-2018 TSIB_1752 8eedb680676637987f36839f75da35c1 813 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 134 597 5.7E-22 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TSIB_1752 8eedb680676637987f36839f75da35c1 813 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 793 812 2.4E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TSIB_0384 162190ac55b21e287c7c2a0fa562b3e6 338 SUPERFAMILY SSF160369 5 141 7.98E-24 T 23-10-2018 TSIB_0384 162190ac55b21e287c7c2a0fa562b3e6 338 Pfam PF00466 Ribosomal protein L10 5 106 9.9E-22 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TSIB_0384 162190ac55b21e287c7c2a0fa562b3e6 338 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 36.062 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea TSIB_0384 162190ac55b21e287c7c2a0fa562b3e6 338 Gene3D G3DSA:3.30.70.1730 15 211 6.6E-75 T 23-10-2018 TSIB_0384 162190ac55b21e287c7c2a0fa562b3e6 338 Gene3D G3DSA:3.90.105.20 107 186 6.6E-75 T 23-10-2018 TSIB_1127 a2255603753b116778a69a14255b9323 355 SUPERFAMILY SSF53067 1 307 3.02E-7 T 23-10-2018 TSIB_1127 a2255603753b116778a69a14255b9323 355 PIRSF PIRSF009433 1 353 1.5E-144 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TSIB_1127 a2255603753b116778a69a14255b9323 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 350 2.1E-130 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TSIB_0754 e24c7b09ce2f5c25e7b463aed47ef675 132 SUPERFAMILY SSF82784 1 128 1.96E-35 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TSIB_0754 e24c7b09ce2f5c25e7b463aed47ef675 132 Pfam PF02566 OsmC-like protein 27 116 7.3E-17 T 23-10-2018 IPR003718 OsmC/Ohr family TSIB_0754 e24c7b09ce2f5c25e7b463aed47ef675 132 Gene3D G3DSA:3.30.300.20 2 130 3.7E-39 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 PIRSF PIRSF006521 28 120 2.4E-27 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 Gene3D G3DSA:3.30.70.60 26 120 6.7E-33 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 19 120 34.779 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 SMART SM00888 30 120 9.4E-27 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 Pfam PF00736 EF-1 guanine nucleotide exchange domain 34 119 1.4E-17 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 SUPERFAMILY SSF54984 34 119 2.09E-16 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 TSIB_1750 b7d2dacbc436dd3ae364de61d518b9f7 120 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 32 119 2.1E-18 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 Pfam PF01037 Lrp/AsnC ligand binding domain 79 150 5.2E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 Gene3D G3DSA:1.10.10.10 8 64 7.7E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 Gene3D G3DSA:3.30.70.920 67 158 2.9E-23 T 23-10-2018 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 SMART SM00344 13 122 6.4E-44 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 SUPERFAMILY SSF46785 12 71 5.53E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 60 3.0E-13 T 23-10-2018 TSIB_1860 3593331c88901a2e79fdf62ea866430f 158 SUPERFAMILY SSF54909 73 151 5.9E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_1711 9d54a98c4e4f917142809f119df70f92 300 SUPERFAMILY SSF103481 74 154 9.42E-12 T 23-10-2018 TSIB_1711 9d54a98c4e4f917142809f119df70f92 300 SUPERFAMILY SSF103481 204 299 3.53E-9 T 23-10-2018 TSIB_1711 9d54a98c4e4f917142809f119df70f92 300 Pfam PF00892 EamA-like transporter family 5 152 3.8E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1711 9d54a98c4e4f917142809f119df70f92 300 Pfam PF00892 EamA-like transporter family 165 298 1.9E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1463 fd240a7c79bd0a73144036c574c85787 154 Gene3D G3DSA:2.60.120.1140 1 122 2.9E-12 T 23-10-2018 IPR038695 Saro_0823-like superfamily TSIB_1463 fd240a7c79bd0a73144036c574c85787 154 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 3.8E-18 T 23-10-2018 IPR003795 Protein of unknown function DUF192 TSIB_1463 fd240a7c79bd0a73144036c574c85787 154 Hamap MF_00263 UPF0127 protein . 2 116 30.161 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 TSIB_1624 79cea9471af7d9c4096d85e2e2d5c31b 96 SUPERFAMILY SSF54285 2 94 7.66E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_1624 79cea9471af7d9c4096d85e2e2d5c31b 96 Pfam PF02597 ThiS family 9 94 1.8E-6 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1624 79cea9471af7d9c4096d85e2e2d5c31b 96 Gene3D G3DSA:3.10.20.30 1 94 2.1E-11 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1129 6f05a35f990d9448d0eb70d1678dde72 353 Pfam PF05763 Protein of unknown function (DUF835) 228 351 1.2E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_0397 a32abca94327fc419b40907cfcc481e0 372 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 1.1E-47 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TSIB_0397 a32abca94327fc419b40907cfcc481e0 372 Gene3D G3DSA:3.40.720.10 1 371 8.5E-54 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSIB_0397 a32abca94327fc419b40907cfcc481e0 372 SUPERFAMILY SSF53649 1 359 1.46E-76 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSIB_0875 8b00469d074018e1960e67e5dfc52369 586 Gene3D G3DSA:3.20.20.70 127 409 4.2E-32 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0875 8b00469d074018e1960e67e5dfc52369 586 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0875 8b00469d074018e1960e67e5dfc52369 586 SUPERFAMILY SSF102114 127 394 1.44E-40 T 23-10-2018 TSIB_0875 8b00469d074018e1960e67e5dfc52369 586 Pfam PF13353 4Fe-4S single cluster domain 142 223 2.0E-6 T 23-10-2018 TSIB_0875 8b00469d074018e1960e67e5dfc52369 586 Pfam PF04055 Radical SAM superfamily 142 301 1.7E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0966 a386cb13afd97ff71c0e551a50b4b66b 249 Gene3D G3DSA:3.40.50.150 1 149 3.5E-49 T 23-10-2018 TSIB_0966 a386cb13afd97ff71c0e551a50b4b66b 249 Gene3D G3DSA:2.20.25.110 150 209 9.4E-32 T 23-10-2018 TSIB_0966 a386cb13afd97ff71c0e551a50b4b66b 249 SUPERFAMILY SSF53335 1 245 1.21E-47 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0966 a386cb13afd97ff71c0e551a50b4b66b 249 Pfam PF13649 Methyltransferase domain 45 139 1.4E-25 T 23-10-2018 TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 Gene3D G3DSA:3.40.50.300 1 202 3.6E-51 T 23-10-2018 TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 SUPERFAMILY SSF46785 279 348 1.9E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 Gene3D G3DSA:1.10.10.10 281 350 1.8E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 Gene3D G3DSA:1.10.8.60 203 280 9.0E-27 T 23-10-2018 TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 SUPERFAMILY SSF52540 2 276 6.35E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0969 58438f7f24bcb31ea0f4638ec410af2f 350 Pfam PF01637 ATPase domain predominantly from Archaea 15 243 1.0E-23 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_1262 bc1a38572215062ec1af0de9bee4721e 122 Gene3D G3DSA:3.40.140.10 1 122 2.4E-26 T 23-10-2018 TSIB_1262 bc1a38572215062ec1af0de9bee4721e 122 SUPERFAMILY SSF102712 2 116 2.22E-25 T 23-10-2018 TSIB_1262 bc1a38572215062ec1af0de9bee4721e 122 Pfam PF14464 Prokaryotic homologs of the JAB domain 11 99 1.5E-10 T 23-10-2018 IPR028090 JAB domain, prokaryotic TSIB_0581 e7f33c59a2ea6eafa83e02988b5abfc6 427 Pfam PF07690 Major Facilitator Superfamily 3 315 2.9E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0581 e7f33c59a2ea6eafa83e02988b5abfc6 427 SUPERFAMILY SSF103473 3 407 1.07E-65 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_0581 e7f33c59a2ea6eafa83e02988b5abfc6 427 Gene3D G3DSA:1.20.1250.20 1 404 2.7E-62 T 23-10-2018 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.0E-29 T 23-10-2018 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 PRINTS PR00959 Mevalonate kinase family signature 106 128 6.0E-29 T 23-10-2018 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 PRINTS PR00959 Mevalonate kinase family signature 282 299 6.0E-29 T 23-10-2018 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 PRINTS PR00959 Mevalonate kinase family signature 149 168 6.0E-29 T 23-10-2018 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 SUPERFAMILY SSF55060 183 328 1.36E-36 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 Gene3D G3DSA:3.30.230.10 1 181 5.8E-52 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 Hamap MF_00217 Mevalonate kinase [mvk]. 3 326 58.894 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 Pfam PF08544 GHMP kinases C terminal 244 309 1.4E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 108 119 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 SUPERFAMILY SSF54211 3 178 3.79E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 Pfam PF00288 GHMP kinases N terminal domain 102 168 2.2E-17 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 297 2.9E-86 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TSIB_1226 7d99e75a64d30291f20de3ab94a07387 333 Gene3D G3DSA:3.30.70.890 186 317 2.0E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 SUPERFAMILY SSF53218 181 320 5.63E-33 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Gene3D G3DSA:3.40.980.10 19 313 6.6E-111 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Gene3D G3DSA:3.90.105.10 27 181 6.6E-111 T 23-10-2018 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 SUPERFAMILY SSF63867 326 396 2.35E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 9.7E-47 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 3.5E-17 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Gene3D G3DSA:2.40.340.10 320 396 6.8E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 2.6E-16 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 SUPERFAMILY SSF63882 7 181 4.32E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 SMART SM00852 186 317 7.1E-29 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0963 5521aa6acd46324fd30ee14f8fcd6d8c 396 Gene3D G3DSA:2.170.190.11 50 148 6.6E-111 T 23-10-2018 TSIB_1481 3762a6af5a15b28765ff94f5d136b91a 67 Gene3D G3DSA:1.10.20.10 1 67 1.5E-24 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1481 3762a6af5a15b28765ff94f5d136b91a 67 SUPERFAMILY SSF47113 3 66 2.6E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1481 3762a6af5a15b28765ff94f5d136b91a 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 1.1E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SMART SM00116 138 186 11.0 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SMART SM00116 72 120 3.9E-9 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SMART SM00116 233 281 3.0E-6 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SMART SM00116 12 61 2.6E-4 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SUPERFAMILY SSF54631 127 280 7.79E-28 T 23-10-2018 TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 Gene3D G3DSA:3.10.580.10 3 124 8.8E-37 T 23-10-2018 TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 SUPERFAMILY SSF54631 3 120 5.05E-26 T 23-10-2018 TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 Pfam PF00571 CBS domain 70 118 2.7E-10 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 Pfam PF00571 CBS domain 5 57 4.1E-7 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 Pfam PF00571 CBS domain 226 281 4.3E-9 T 23-10-2018 IPR000644 CBS domain TSIB_1476 2e643a9fc6ba5726b6c0ed85ff9fafea 284 Pfam PF00571 CBS domain 141 183 2.6E-5 T 23-10-2018 IPR000644 CBS domain TSIB_1555 c10324905d65005c3235f262885ca64b 144 Pfam PF01951 Archease protein family (MTH1598/TM1083) 7 144 4.2E-45 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TSIB_1555 c10324905d65005c3235f262885ca64b 144 SUPERFAMILY SSF69819 5 144 1.16E-48 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TSIB_1555 c10324905d65005c3235f262885ca64b 144 Gene3D G3DSA:3.55.10.10 3 144 8.1E-53 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TSIB_1555 c10324905d65005c3235f262885ca64b 144 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 11 144 4.0E-34 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TSIB_1555 c10324905d65005c3235f262885ca64b 144 Hamap MF_01222 Protein archease. 5 144 40.955 T 23-10-2018 IPR022952 Archease, archaea TSIB_0467 ca6e1214495a1eea169698d0482cfc8c 426 Gene3D G3DSA:1.10.4160.10 4 403 4.1E-63 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily TSIB_0467 ca6e1214495a1eea169698d0482cfc8c 426 PIRSF PIRSF002744 1 426 4.9E-59 T 23-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 TSIB_0467 ca6e1214495a1eea169698d0482cfc8c 426 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 9 387 3.6E-46 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 TSIB_0467 ca6e1214495a1eea169698d0482cfc8c 426 TIGRFAM TIGR02358 thia_cytX: putative hydroxymethylpyrimidine transporter CytX 22 424 2.1E-128 T 23-10-2018 IPR012732 Hydroxymethylpyrimidine transporter CytX TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 SUPERFAMILY SSF52540 333 577 3.69E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 Pfam PF00664 ABC transporter transmembrane region 27 297 1.9E-56 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 Gene3D G3DSA:3.40.50.300 338 581 4.8E-88 T 23-10-2018 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 Pfam PF00005 ABC transporter 358 506 3.1E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 Gene3D G3DSA:1.20.1560.10 1 329 5.5E-92 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 SUPERFAMILY SSF90123 14 325 4.84E-82 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1079 8992ec6366915ca3e99ce9f9b315b3a8 581 SMART SM00382 367 553 3.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 SUPERFAMILY SSF52540 67 256 2.06E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 Gene3D G3DSA:3.40.50.300 1 297 1.5E-86 T 23-10-2018 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 SUPERFAMILY SSF54862 5 92 9.07E-17 T 23-10-2018 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 Pfam PF00005 ABC transporter 67 209 1.6E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 SUPERFAMILY SSF52540 307 500 3.5E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 SMART SM00382 334 502 4.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 SMART SM00382 69 257 2.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 Pfam PF00037 4Fe-4S binding domain 16 38 6.6E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 PRINTS PR01868 ABC transporter family E signature 105 121 8.8E-58 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 PRINTS PR01868 ABC transporter family E signature 74 99 8.8E-58 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 PRINTS PR01868 ABC transporter family E signature 19 43 8.8E-58 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 PRINTS PR01868 ABC transporter family E signature 46 66 8.8E-58 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 PRINTS PR01868 ABC transporter family E signature 121 147 8.8E-58 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 Pfam PF00005 ABC transporter 329 453 1.5E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 22 33 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0669 87f910fa69bc97dace3c7033c212a1d0 562 Gene3D G3DSA:3.40.50.300 299 560 1.1E-67 T 23-10-2018 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 82 96 2.7E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 37 51 2.7E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 56 69 2.7E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 72 82 2.7E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 8 127 35.121 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 11 126 2.4E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00884 Ribosomal protein HS6 signature 45 55 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00884 Ribosomal protein HS6 signature 82 92 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00884 Ribosomal protein HS6 signature 11 22 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00884 Ribosomal protein HS6 signature 55 66 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 PRINTS PR00884 Ribosomal protein HS6 signature 96 112 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 SUPERFAMILY SSF55315 9 125 8.54E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 75 92 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 Gene3D G3DSA:3.30.1330.30 3 128 1.5E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_0419 13f86fc57d576fb766293ac9fe54c034 128 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 23 115 2.3E-31 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 SMART SM00790 4 207 1.5E-113 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 Gene3D G3DSA:1.10.569.10 241 430 1.2E-121 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 SUPERFAMILY SSF48310 213 612 1.96E-112 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 Gene3D G3DSA:1.10.599.10 239 605 1.2E-121 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 SUPERFAMILY SSF56228 1 211 9.16E-76 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1619 5043f16525600d614fe3079f12a713e6 612 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 1.8E-79 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1619 5043f16525600d614fe3079f12a713e6 612 Gene3D G3DSA:3.60.9.10 1 211 1.1E-86 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1619 5043f16525600d614fe3079f12a713e6 612 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 222 605 6.5E-121 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0046 70b49b85b095e11e50fbad04a56cf768 104 SUPERFAMILY SSF81301 3 103 4.5E-18 T 23-10-2018 TSIB_0046 70b49b85b095e11e50fbad04a56cf768 104 Gene3D G3DSA:3.30.460.10 1 101 1.1E-18 T 23-10-2018 TSIB_0046 70b49b85b095e11e50fbad04a56cf768 104 Pfam PF01909 Nucleotidyltransferase domain 8 78 3.2E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1143 a8917be8de0ea3f6f185222625dc3216 146 SUPERFAMILY SSF47240 2 144 1.56E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1143 a8917be8de0ea3f6f185222625dc3216 146 Pfam PF02915 Rubrerythrin 5 138 9.3E-10 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1143 a8917be8de0ea3f6f185222625dc3216 146 Gene3D G3DSA:1.20.1260.10 1 144 6.4E-16 T 23-10-2018 IPR012347 Ferritin-like TSIB_0479 d9f66ac71264dd0ef6c82511ad7b8825 76 Pfam PF02597 ThiS family 6 76 1.4E-6 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_0479 d9f66ac71264dd0ef6c82511ad7b8825 76 SUPERFAMILY SSF54285 1 76 4.67E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_0479 d9f66ac71264dd0ef6c82511ad7b8825 76 Gene3D G3DSA:3.10.20.30 1 76 6.5E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_0687 91b535d462c3725ed1d4b68e443170d8 118 Hamap MF_00674 UPF0251 protein . 6 103 23.687 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TSIB_0687 91b535d462c3725ed1d4b68e443170d8 118 SUPERFAMILY SSF88659 40 87 6.73E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSIB_0687 91b535d462c3725ed1d4b68e443170d8 118 Pfam PF02001 Protein of unknown function DUF134 5 98 4.8E-26 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TSIB_0687 91b535d462c3725ed1d4b68e443170d8 118 Gene3D G3DSA:1.10.10.10 39 88 2.6E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 4 133 2.9E-55 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 SUPERFAMILY SSF89915 19 122 1.19E-22 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 SMART SM00421 6 64 0.0051 T 23-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 Pfam PF04545 Sigma-70, region 4 9 51 6.7E-8 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 Gene3D G3DSA:3.30.1190.10 19 137 2.7E-37 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 Pfam PF14601 DNA_binding protein, TFX, C-term 54 134 2.1E-24 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal TSIB_0084 ad1ac37d92cd32c07766873f1b60520b 148 PIRSF PIRSF004932 5 148 4.5E-62 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TSIB_0604 20418255a61847a0b13cba9ec5d9bb9c 120 Gene3D G3DSA:1.10.287.420 1 54 3.9E-27 T 23-10-2018 TSIB_0604 20418255a61847a0b13cba9ec5d9bb9c 120 SUPERFAMILY SSF47819 1 115 1.44E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TSIB_0604 20418255a61847a0b13cba9ec5d9bb9c 120 Gene3D G3DSA:1.10.150.80 55 120 3.2E-24 T 23-10-2018 TSIB_0604 20418255a61847a0b13cba9ec5d9bb9c 120 PIRSF PIRSF005053 1 120 6.8E-30 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) TSIB_0604 20418255a61847a0b13cba9ec5d9bb9c 120 Pfam PF03874 RNA polymerase Rpb4 12 119 8.5E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 TSIB_0371 039123d94f47729057237211fff814ac 197 Pfam PF08745 PINc domain ribonuclease 6 194 3.1E-66 T 23-10-2018 IPR014856 PIN-domain ribonuclease TSIB_0371 039123d94f47729057237211fff814ac 197 SUPERFAMILY SSF88723 76 193 5.61E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0371 039123d94f47729057237211fff814ac 197 Hamap MF_01078 UPF0278 protein . 4 197 31.575 T 23-10-2018 IPR014856 PIN-domain ribonuclease TSIB_0371 039123d94f47729057237211fff814ac 197 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 6 193 2.3E-70 T 23-10-2018 IPR014856 PIN-domain ribonuclease TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Gene3D G3DSA:3.30.1490.70 70 241 2.1E-69 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Gene3D G3DSA:3.30.70.3360 314 362 9.2E-36 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Gene3D G3DSA:3.30.70.3350 244 372 9.2E-36 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Pfam PF09414 RNA ligase 86 240 3.9E-19 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Gene3D G3DSA:2.20.25.320 7 67 5.9E-23 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 Gene3D G3DSA:3.30.470.30 96 197 2.1E-69 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 236 249 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 5.4E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 SUPERFAMILY SSF56091 63 242 4.16E-39 T 23-10-2018 TSIB_1335 07c7fa11773991a4764ddabf80514f1d 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 13 380 1.7E-143 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TSIB_1859 53225b24ce9f52654914bde13df61bfa 186 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 39.574 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TSIB_1859 53225b24ce9f52654914bde13df61bfa 186 Pfam PF01725 Ham1 family 3 178 3.0E-49 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSIB_1859 53225b24ce9f52654914bde13df61bfa 186 SUPERFAMILY SSF52972 1 182 1.05E-60 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSIB_1859 53225b24ce9f52654914bde13df61bfa 186 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 3.2E-64 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSIB_1859 53225b24ce9f52654914bde13df61bfa 186 Gene3D G3DSA:3.90.950.10 1 185 3.0E-71 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 8 87 1.6E-21 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 SMART SM00738 6 90 1.4E-20 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 8 151 37.907 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 Gene3D G3DSA:3.30.70.940 5 90 1.4E-31 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 SUPERFAMILY SSF50104 59 150 4.14E-16 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 10 153 2.5E-51 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 Gene3D G3DSA:2.30.30.30 91 155 2.6E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 Pfam PF00467 KOW motif 98 129 7.1E-9 T 23-10-2018 IPR005824 KOW TSIB_0381 2e100cedaff1a038f6b4a94c997383dc 155 SMART SM00739 95 122 3.1E-7 T 23-10-2018 IPR005824 KOW TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 Gene3D G3DSA:3.30.360.10 126 303 5.8E-84 T 23-10-2018 TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 SUPERFAMILY SSF55347 130 288 5.07E-28 T 23-10-2018 TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 Gene3D G3DSA:3.40.50.720 5 291 5.8E-84 T 23-10-2018 TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 125 3.5E-30 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 218 1.6E-5 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSIB_2031 edbcf1927e3476ec4ef1958ed0f35e6e 319 SUPERFAMILY SSF51735 4 153 4.01E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:2.170.16.10 222 363 2.0E-5 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 221 318 1.1E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:3.10.28.10 422 605 3.4E-14 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SMART SM00305 649 700 5.5E-6 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SUPERFAMILY SSF54211 917 1090 1.4E-41 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:3.40.50.300 23 135 6.9E-31 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:3.40.50.300 631 797 2.1E-31 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 912 1092 1.8E-35 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SUPERFAMILY SSF52540 39 891 3.13E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SUPERFAMILY SSF51294 221 693 1.94E-13 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SMART SM00306 219 338 7.3E-15 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 SUPERFAMILY SSF55608 514 628 3.19E-10 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Pfam PF14890 Intein splicing domain 230 694 1.1E-9 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Pfam PF01078 Magnesium chelatase, subunit ChlI 44 96 3.5E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 27 1105 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Pfam PF13654 AAA domain 700 887 1.2E-18 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 917 933 3.7E-28 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 1024 1043 3.7E-28 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 70 89 3.7E-28 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 1047 1065 3.7E-28 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 994 1013 3.7E-28 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:1.10.8.60 798 890 1.7E-42 T 23-10-2018 TSIB_0089 549b5dd2dc37144589628573b46f9028 1112 Gene3D G3DSA:3.30.230.10 909 1112 1.5E-75 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1640 f84d0d8222e4ddef1f32bc70a7d13bd7 86 Pfam PF00364 Biotin-requiring enzyme 10 81 3.4E-18 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TSIB_1640 f84d0d8222e4ddef1f32bc70a7d13bd7 86 Gene3D G3DSA:2.40.50.100 5 86 3.3E-24 T 23-10-2018 TSIB_1640 f84d0d8222e4ddef1f32bc70a7d13bd7 86 SUPERFAMILY SSF51230 4 85 5.23E-25 T 23-10-2018 IPR011053 Single hybrid motif TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 SUPERFAMILY SSF103025 2 307 2.67E-93 T 23-10-2018 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 PIRSF PIRSF006487 1 397 2.5E-103 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 386 6.3E-93 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 SUPERFAMILY SSF101790 299 391 7.03E-24 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 292 381 6.5E-24 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 286 2.2E-97 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Gene3D G3DSA:2.40.30.110 309 382 5.8E-30 T 23-10-2018 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Gene3D G3DSA:4.10.1250.10 267 304 5.5E-10 T 23-10-2018 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Gene3D G3DSA:3.30.1360.120 7 254 2.2E-89 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 388 42.368 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSIB_0661 71cd66cc6b97b0e102cc4ad63b2d0141 397 Gene3D G3DSA:3.30.70.1400 51 142 2.2E-89 T 23-10-2018 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Hamap MF_02132 AMP phosphorylase. 1 503 47.049 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 387 2.5E-13 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 1.6E-224 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 3.1E-239 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 SUPERFAMILY SSF47648 86 153 3.92E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Gene3D G3DSA:3.90.1170.30 413 493 3.8E-26 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 SUPERFAMILY SSF54680 412 495 3.79E-17 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 SMART SM00941 424 491 4.7E-19 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Gene3D G3DSA:3.40.1030.10 152 412 4.5E-99 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 SUPERFAMILY SSF52418 155 404 3.66E-67 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 SUPERFAMILY SSF50692 6 82 7.08E-7 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 1.2E-13 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Gene3D G3DSA:2.40.40.20 1 83 2.9E-33 T 23-10-2018 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Gene3D G3DSA:1.20.970.10 84 151 2.3E-23 T 23-10-2018 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 PIRSF PIRSF000478 84 502 5.5E-123 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 3.4E-14 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0680 734fdb2a24c5e35456c2b08051cd389f 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0953 1b98ac478841d14ef8afad5d1f1293bd 169 Pfam PF04167 Protein of unknown function (DUF402) 56 123 2.5E-12 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TSIB_0953 1b98ac478841d14ef8afad5d1f1293bd 169 SUPERFAMILY SSF159234 4 164 1.57E-38 T 23-10-2018 IPR035930 FomD-like superfamily TSIB_0953 1b98ac478841d14ef8afad5d1f1293bd 169 Gene3D G3DSA:2.40.380.10 49 168 8.6E-13 T 23-10-2018 IPR035930 FomD-like superfamily TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 SUPERFAMILY SSF55681 95 437 1.28E-100 T 23-10-2018 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 5.0E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 5.0E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 5.0E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 5.0E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.253 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 9.9E-178 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 4.5E-93 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 Gene3D G3DSA:2.40.50.140 1 105 3.2E-27 T 23-10-2018 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 Pfam PF01336 OB-fold nucleic acid binding domain 20 97 3.8E-13 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 Gene3D G3DSA:3.30.930.10 107 438 1.6E-121 T 23-10-2018 TSIB_0435 b746b21af1f37ec428801c28da0e4185 438 SUPERFAMILY SSF50249 1 102 1.35E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1180 e75c50b9046b5d5eddd2ce9e4cc12897 194 Pfam PF04407 Protein of unknown function (DUF531) 12 182 3.6E-79 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TSIB_1180 e75c50b9046b5d5eddd2ce9e4cc12897 194 PIRSF PIRSF006006 8 191 2.8E-88 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 7 148 1.2E-30 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 Gene3D G3DSA:3.40.50.1450 4 151 7.8E-35 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 SUPERFAMILY SSF53163 4 150 3.27E-30 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 PRINTS PR00446 Hydrogen uptake protein signature 66 82 3.3E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 PRINTS PR00446 Hydrogen uptake protein signature 54 64 3.3E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 PRINTS PR00446 Hydrogen uptake protein signature 6 18 3.3E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 PRINTS PR00446 Hydrogen uptake protein signature 18 29 3.3E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_0286 b7d549a30ccfa0f69e072c45fa5e07a2 151 Pfam PF01750 Hydrogenase maturation protease 30 147 6.2E-20 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1528 713916b0745b275af11942fb7621357c 350 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 344 38.635 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TSIB_1528 713916b0745b275af11942fb7621357c 350 Gene3D G3DSA:3.65.10.20 4 326 2.1E-121 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily TSIB_1528 713916b0745b275af11942fb7621357c 350 Gene3D G3DSA:3.30.360.20 179 282 2.1E-121 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TSIB_1528 713916b0745b275af11942fb7621357c 350 PIRSF PIRSF005378 1 349 6.8E-108 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 TSIB_1528 713916b0745b275af11942fb7621357c 350 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site TSIB_1528 713916b0745b275af11942fb7621357c 350 Pfam PF01137 RNA 3'-terminal phosphate cyclase 8 332 4.1E-76 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain TSIB_1528 713916b0745b275af11942fb7621357c 350 SUPERFAMILY SSF55205 2 235 3.27E-66 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TSIB_1528 713916b0745b275af11942fb7621357c 350 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 3 330 1.3E-122 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TSIB_1528 713916b0745b275af11942fb7621357c 350 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 183 281 4.5E-23 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 Gene3D G3DSA:3.20.20.140 55 344 1.1E-155 T 23-10-2018 TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 49.083 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 Pfam PF01979 Amidohydrolase family 51 398 2.9E-82 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 Gene3D G3DSA:2.30.40.10 4 415 1.1E-155 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 SUPERFAMILY SSF51556 54 347 1.23E-102 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_1980 aa468cfeacb86d2d74c049e9c2df31d3 424 SUPERFAMILY SSF51338 1 423 5.15E-38 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_1781 ef5bb0573b0913bc935590ad36f5ba30 90 SUPERFAMILY SSF54197 1 80 7.73E-21 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_1781 ef5bb0573b0913bc935590ad36f5ba30 90 Gene3D G3DSA:3.30.428.10 1 89 6.9E-22 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_1781 ef5bb0573b0913bc935590ad36f5ba30 90 Pfam PF01230 HIT domain 10 81 1.6E-10 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 10 57 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 Hamap MF_02113_A Proteasome subunit beta [prcB]. 2 198 34.607 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 SUPERFAMILY SSF56235 4 192 1.63E-57 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 Gene3D G3DSA:3.60.20.10 1 198 5.8E-61 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 190 1.6E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 Pfam PF00227 Proteasome subunit 4 178 4.5E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 PRINTS PR00141 Proteasome component signature 14 29 3.2E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 PRINTS PR00141 Proteasome component signature 134 145 3.2E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1202 5c3fcaa9d16041c387ba5cc582f4bcae 199 PRINTS PR00141 Proteasome component signature 145 156 3.2E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1353 b1bd0cec07955d71f1737f4f8f511047 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.5E-22 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TSIB_1353 b1bd0cec07955d71f1737f4f8f511047 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.562 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TSIB_1353 b1bd0cec07955d71f1737f4f8f511047 120 PIRSF PIRSF004952 4 120 1.8E-46 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 TSIB_1353 b1bd0cec07955d71f1737f4f8f511047 120 Gene3D G3DSA:3.30.70.3250 1 120 1.2E-49 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TSIB_1353 b1bd0cec07955d71f1737f4f8f511047 120 SUPERFAMILY SSF160350 4 118 8.63E-36 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TSIB_1756 beef3f11137112bacdd955aba363864d 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 4.4E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1756 beef3f11137112bacdd955aba363864d 322 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1756 beef3f11137112bacdd955aba363864d 322 Pfam PF00005 ABC transporter 29 185 1.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1756 beef3f11137112bacdd955aba363864d 322 Gene3D G3DSA:3.40.50.300 5 322 9.8E-102 T 23-10-2018 TSIB_1756 beef3f11137112bacdd955aba363864d 322 SUPERFAMILY SSF52540 8 257 1.15E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1756 beef3f11137112bacdd955aba363864d 322 SMART SM00382 37 243 2.3E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1756 beef3f11137112bacdd955aba363864d 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 6.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 11 217 2.5E-62 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 Gene3D G3DSA:3.40.50.150 1 221 2.6E-93 T 23-10-2018 TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 5 219 40.21 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 SUPERFAMILY SSF53335 4 214 9.29E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1093 977350cf9a0cd11d028d5d1bc68b9da2 221 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 216 5.8E-67 T 23-10-2018 TSIB_1963 22e29c59ad27648087c18be37aab76d6 225 Gene3D G3DSA:3.90.850.10 3 221 6.6E-92 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSIB_1963 22e29c59ad27648087c18be37aab76d6 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 5.7E-69 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSIB_1963 22e29c59ad27648087c18be37aab76d6 225 SUPERFAMILY SSF56529 14 217 5.89E-81 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSIB_0597 2d99f046eb0df47fc08a24e22cf6b494 274 ProDom PD039347 PF1398 MJ0538 PH1392 4 254 6.0E-68 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 126 141 1.0E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 332 353 1.0E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 141 157 1.0E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 165 178 1.0E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 SUPERFAMILY SSF47323 518 644 5.69E-32 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 SMART SM00836 522 644 3.3E-47 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Gene3D G3DSA:3.40.50.620 123 525 2.3E-152 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Gene3D G3DSA:3.30.1360.70 6 122 4.5E-34 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 136 145 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 SMART SM01016 12 96 2.4E-30 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 SUPERFAMILY SSF52374 121 515 3.87E-79 T 23-10-2018 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 368 2.3E-84 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 SUPERFAMILY SSF55190 12 117 2.35E-24 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Pfam PF05746 DALR anticodon binding domain 522 644 3.1E-34 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Pfam PF00750 tRNA synthetases class I (R) 106 367 1.1E-24 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Pfam PF00750 tRNA synthetases class I (R) 390 496 1.1E-12 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Gene3D G3DSA:1.10.730.10 526 644 2.1E-40 T 23-10-2018 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 644 27.656 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSIB_1925 80491a094b2ba90bf940e656fd6cab38 644 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 96 4.5E-22 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_1522 3fbb528a65bc825104fb6eed6b2cf4f0 246 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 13 149 7.2E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1522 3fbb528a65bc825104fb6eed6b2cf4f0 246 Gene3D G3DSA:3.40.50.700 2 163 3.5E-36 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TSIB_1522 3fbb528a65bc825104fb6eed6b2cf4f0 246 SUPERFAMILY SSF56770 4 211 9.03E-41 T 23-10-2018 TSIB_0550 2f9c61c91f382e8e2d18cb3c1b40bfa0 242 Pfam PF12844 Helix-turn-helix domain 27 75 1.8E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0550 2f9c61c91f382e8e2d18cb3c1b40bfa0 242 SUPERFAMILY SSF47413 22 75 1.05E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_0550 2f9c61c91f382e8e2d18cb3c1b40bfa0 242 PIRSF PIRSF037724 1 237 5.0E-102 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted TSIB_0550 2f9c61c91f382e8e2d18cb3c1b40bfa0 242 SMART SM00530 26 81 2.5E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0550 2f9c61c91f382e8e2d18cb3c1b40bfa0 242 Gene3D G3DSA:1.10.260.40 24 80 3.1E-10 T 23-10-2018 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 Pfam PF13424 Tetratricopeptide repeat 95 166 2.7E-8 T 23-10-2018 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 SUPERFAMILY SSF48452 47 235 3.79E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 SMART SM00028 56 89 110.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 SMART SM00028 94 127 0.043 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 SMART SM00028 134 167 120.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 SMART SM00028 174 207 300.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_1749 d79c7fc2c4de23b33f57a9bd8145e2e0 341 Gene3D G3DSA:1.25.40.10 37 331 2.2E-21 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0368 c0586af64262507e9e5f0c8247726936 334 SUPERFAMILY SSF50331 237 307 2.04E-5 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSIB_0368 c0586af64262507e9e5f0c8247726936 334 Gene3D G3DSA:3.40.50.300 2 237 3.0E-71 T 23-10-2018 TSIB_0368 c0586af64262507e9e5f0c8247726936 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0368 c0586af64262507e9e5f0c8247726936 334 Pfam PF00005 ABC transporter 22 160 2.4E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0368 c0586af64262507e9e5f0c8247726936 334 SMART SM00382 27 210 4.9E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0368 c0586af64262507e9e5f0c8247726936 334 SUPERFAMILY SSF52540 4 241 2.28E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 ProSitePatterns PS00211 ABC transporters family signature. 40 54 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 Gene3D G3DSA:3.40.50.300 1 204 7.3E-62 T 23-10-2018 TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 Pfam PF00005 ABC transporter 16 67 2.3E-10 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 SUPERFAMILY SSF52540 8 202 2.32E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 117 203 1.8E-33 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_0924 bef543b812bbd9b73cc42a772ccaa7f3 204 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 119 183 2.6E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 SUPERFAMILY SSF53383 6 421 4.08E-130 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 414 42.311 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 Pfam PF00464 Serine hydroxymethyltransferase 9 386 1.2E-77 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 PIRSF PIRSF000412 1 424 6.3E-143 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 Gene3D G3DSA:3.40.640.10 32 279 5.6E-81 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0622 9a2f6b958ba2b2adea37de078583ff75 425 Gene3D G3DSA:3.90.1150.10 280 423 5.3E-54 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1818 65b4b55304949734949f2c1433db1eb8 219 Gene3D G3DSA:3.60.21.10 20 131 2.2E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_1818 65b4b55304949734949f2c1433db1eb8 219 Pfam PF00149 Calcineurin-like phosphoesterase 20 129 8.9E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_1818 65b4b55304949734949f2c1433db1eb8 219 PIRSF PIRSF000887 2 216 1.3E-40 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TSIB_1818 65b4b55304949734949f2c1433db1eb8 219 SUPERFAMILY SSF56300 20 154 6.11E-15 T 23-10-2018 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 SMART SM00385 210 291 1.2E-12 T 23-10-2018 IPR013763 Cyclin-like TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 SMART SM00385 114 195 2.3E-12 T 23-10-2018 IPR013763 Cyclin-like TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Gene3D G3DSA:1.10.472.10 207 299 1.7E-26 T 23-10-2018 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Pfam PF00382 Transcription factor TFIIB repeat 118 186 1.3E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 1.3E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 SUPERFAMILY SSF47954 206 298 1.22E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Gene3D G3DSA:1.10.472.170 6 197 9.5E-69 T 23-10-2018 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 3.1E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Pfam PF08271 TFIIB zinc-binding 6 47 9.9E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 SUPERFAMILY SSF57783 4 50 2.21E-18 T 23-10-2018 TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 SUPERFAMILY SSF47954 108 199 9.24E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily TSIB_0527 65b351b1f8fecfc2c5a874728b30af13 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.656 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 298 3.3E-106 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 5.3E-77 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 SMART SM00962 104 299 5.8E-107 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 Gene3D G3DSA:3.40.50.300 90 298 2.0E-82 T 23-10-2018 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 Pfam PF02881 SRP54-type protein, helical bundle domain 5 80 7.2E-13 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 SMART SM00382 103 298 5.3E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 SUPERFAMILY SSF52540 102 298 1.13E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 SMART SM00963 1 85 7.3E-16 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 56.74 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 Gene3D G3DSA:1.20.120.140 3 87 7.0E-23 T 23-10-2018 TSIB_0409 8e4edb4acc19b60b8b13860f6650da91 300 SUPERFAMILY SSF47364 1 88 2.62E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 SUPERFAMILY SSF48179 150 255 2.55E-35 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 91 1.6E-21 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 Gene3D G3DSA:1.10.3730.10 154 256 6.5E-37 T 23-10-2018 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 SUPERFAMILY SSF51735 1 149 3.34E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 253 4.0E-79 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 255 26.175 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 151 253 2.2E-36 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 211 233 - T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 PIRSF PIRSF000193 1 258 1.2E-74 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSIB_0621 d4b28447d13b04d7a912a2cdcb63782c 260 Gene3D G3DSA:3.40.50.720 1 153 1.8E-46 T 23-10-2018 TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 PIRSF PIRSF006593 1 281 1.6E-93 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 Gene3D G3DSA:3.40.50.10880 133 281 7.3E-54 T 23-10-2018 TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 SUPERFAMILY SSF111321 1 280 3.14E-79 T 23-10-2018 IPR036075 AF1104-like superfamily TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 Gene3D G3DSA:1.10.8.380 1 67 6.4E-23 T 23-10-2018 TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 Pfam PF01937 Protein of unknown function DUF89 4 278 2.6E-49 T 23-10-2018 IPR002791 Domain of unknown function DUF89 TSIB_1422 976fa1a7bee1bddae6ed31246131d200 281 Gene3D G3DSA:1.10.285.20 68 132 1.2E-22 T 23-10-2018 TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Gene3D G3DSA:1.10.287.510 399 511 5.8E-7 T 23-10-2018 TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Pfam PF13514 AAA domain 9 107 3.0E-6 T 23-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Pfam PF04423 Rad50 zinc hook motif 433 475 1.6E-5 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 SUPERFAMILY SSF52540 9 878 2.67E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Gene3D G3DSA:3.40.50.300 9 235 3.5E-35 T 23-10-2018 TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Gene3D G3DSA:3.40.50.300 610 891 4.1E-34 T 23-10-2018 TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 9 889 11.82 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type TSIB_0096 5ee15b540499a76ee019c553d22dfa44 895 SUPERFAMILY SSF75712 399 495 2.22E-8 T 23-10-2018 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Gene3D G3DSA:1.10.10.770 319 433 2.4E-38 T 23-10-2018 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Gene3D G3DSA:3.40.50.620 4 270 8.4E-105 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 37.485 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Gene3D G3DSA:1.10.10.350 434 526 5.3E-25 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Gene3D G3DSA:1.10.10.860 271 318 2.8E-24 T 23-10-2018 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 1.8E-160 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 SUPERFAMILY SSF48163 323 523 8.5E-48 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Gene3D G3DSA:2.30.30.300 170 213 8.4E-105 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 3.2E-130 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0119 789dcd7fb6a914011f4deb1d5e46f198 526 SUPERFAMILY SSF52374 3 319 8.85E-67 T 23-10-2018 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 36 360 2.2E-135 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 SMART SM00864 48 239 5.6E-107 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 Gene3D G3DSA:3.40.50.1440 39 254 1.1E-82 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 44 368 38.212 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 48 208 4.4E-46 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 SMART SM00865 241 357 1.9E-50 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 Pfam PF12327 FtsZ family, C-terminal domain 256 348 1.2E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 ProSitePatterns PS01135 FtsZ protein signature 2. 132 153 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 SUPERFAMILY SSF55307 238 352 2.75E-39 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 ProSitePatterns PS01134 FtsZ protein signature 1. 79 113 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 Gene3D G3DSA:3.30.1330.20 259 370 9.5E-36 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 SUPERFAMILY SSF52490 47 242 1.57E-69 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 PRINTS PR00423 Cell division protein FtsZ signature 223 245 1.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 PRINTS PR00423 Cell division protein FtsZ signature 246 267 1.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 PRINTS PR00423 Cell division protein FtsZ signature 161 182 1.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0379 a77bc8df1f371c4df0afbbd429e8e6f5 378 PRINTS PR00423 Cell division protein FtsZ signature 133 153 1.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1389 ded64c2cd8d172f63be6a0797639fb68 65 Pfam PF01381 Helix-turn-helix 5 58 5.9E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1389 ded64c2cd8d172f63be6a0797639fb68 65 SUPERFAMILY SSF47413 2 64 4.29E-21 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_1389 ded64c2cd8d172f63be6a0797639fb68 65 SMART SM00530 4 59 4.0E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1389 ded64c2cd8d172f63be6a0797639fb68 65 Gene3D G3DSA:1.10.260.40 1 65 1.3E-31 T 23-10-2018 TSIB_2019 779b3888debcec2a70310489a4423f84 472 SUPERFAMILY SSF53448 5 228 3.34E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2019 779b3888debcec2a70310489a4423f84 472 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 227 35.264 T 23-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSIB_2019 779b3888debcec2a70310489a4423f84 472 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 221 1.1E-49 T 23-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSIB_2019 779b3888debcec2a70310489a4423f84 472 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 367 395 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSIB_2019 779b3888debcec2a70310489a4423f84 472 Gene3D G3DSA:3.40.50.720 253 464 3.2E-38 T 23-10-2018 TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 354 370 2.3E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 309 320 2.3E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 380 399 2.3E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 401 418 2.3E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 255 272 2.3E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PIRSF PIRSF036586 1 469 9.2E-148 T 23-10-2018 IPR012115 Bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase KEGG: 00040+1.1.1.405+2.7.7.40|KEGG: 00515+2.7.7.40|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7818|MetaCyc: PWY-7981 TSIB_2019 779b3888debcec2a70310489a4423f84 472 Gene3D G3DSA:3.90.550.10 2 230 5.5E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2019 779b3888debcec2a70310489a4423f84 472 SUPERFAMILY SSF51735 249 456 6.5E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 309 320 8.6E-6 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 380 399 8.6E-6 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_2019 779b3888debcec2a70310489a4423f84 472 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 103 110 - T 23-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSIB_2019 779b3888debcec2a70310489a4423f84 472 Pfam PF00106 short chain dehydrogenase 289 420 1.3E-23 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 2.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 2.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 2.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 664 1.0E-187 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Gene3D G3DSA:3.40.50.620 16 651 1.7E-230 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 SUPERFAMILY SSF47323 677 912 3.18E-58 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Gene3D G3DSA:1.10.730.10 670 853 1.8E-53 T 23-10-2018 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 876 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 3.5E-37 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 SUPERFAMILY SSF52374 7 674 1.32E-133 T 23-10-2018 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Gene3D G3DSA:3.90.740.10 199 405 1.7E-230 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1070 13.641 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_1124 40c0c6cbfc012a6a7b83a69050d08399 1070 SUPERFAMILY SSF50677 202 401 2.51E-55 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSIB_1168 3d4a6f2fea48510625b4b2c3063e7a9c 331 Gene3D G3DSA:3.40.50.620 11 327 1.2E-87 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1168 3d4a6f2fea48510625b4b2c3063e7a9c 331 Pfam PF01171 PP-loop family 60 238 1.3E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSIB_1168 3d4a6f2fea48510625b4b2c3063e7a9c 331 PIRSF PIRSF004976 8 326 2.2E-109 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TSIB_1168 3d4a6f2fea48510625b4b2c3063e7a9c 331 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 214 313 5.6E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TSIB_1168 3d4a6f2fea48510625b4b2c3063e7a9c 331 SUPERFAMILY SSF52402 35 267 3.09E-54 T 23-10-2018 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Gene3D G3DSA:3.20.20.105 2 360 6.9E-121 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 490 579 1.3E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 SUPERFAMILY SSF88802 361 506 6.21E-37 T 23-10-2018 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Pfam PF01472 PUA domain 510 581 3.1E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 SUPERFAMILY SSF51713 8 358 1.7E-112 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Pfam PF01702 Queuine tRNA-ribosyltransferase 113 334 1.7E-39 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Gene3D G3DSA:3.10.450.90 431 505 9.3E-27 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Gene3D G3DSA:3.90.1020.10 361 430 2.7E-22 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 10 342 4.4E-83 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 10 392 2.4E-161 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 361 429 8.5E-36 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 SUPERFAMILY SSF88697 508 582 1.55E-19 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 440 507 4.1E-22 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 10 535 47.24 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 SMART SM00359 509 583 8.6E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_0093 2111ab2d02f35d5fa6310ff1ad9d1437 584 Gene3D G3DSA:2.30.130.10 506 583 1.8E-31 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 307 25.421 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 Pfam PF01867 CRISPR associated protein Cas1 8 277 1.3E-83 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 Gene3D G3DSA:3.100.10.20 1 82 7.2E-30 T 23-10-2018 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 317 2.6E-96 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 6 321 1.4E-134 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 TSIB_1492 96a88a3b1cf8913eac92371b28e18013 322 Gene3D G3DSA:1.20.120.920 83 322 1.8E-67 T 23-10-2018 TSIB_1488 d7acc9d94f45f652e7b6af2d8e9453ad 294 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 10 206 4.9E-35 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap TSIB_1488 d7acc9d94f45f652e7b6af2d8e9453ad 294 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 13 207 6.6E-20 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TSIB_1488 d7acc9d94f45f652e7b6af2d8e9453ad 294 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 81 240 6.8E-8 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TSIB_1366 c1733668801d3e2ee0ddae149c016546 441 Pfam PF01523 Putative modulator of DNA gyrase 17 304 3.1E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSIB_1366 c1733668801d3e2ee0ddae149c016546 441 Gene3D G3DSA:3.30.2290.10 2 206 2.6E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSIB_1366 c1733668801d3e2ee0ddae149c016546 441 SUPERFAMILY SSF111283 6 441 3.4E-87 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 Gene3D G3DSA:4.10.910.10 95 145 6.1E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 15 155 25.355 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 Gene3D G3DSA:1.10.8.50 6 83 6.9E-27 T 23-10-2018 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 SUPERFAMILY SSF46946 16 151 1.25E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 PIRSF PIRSF002134 8 156 6.2E-42 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 11 155 5.5E-61 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 Pfam PF00416 Ribosomal protein S13/S18 17 145 1.2E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0339 4d5eb2ca951c91a7084efe918f4d93b1 156 ProSitePatterns PS00646 Ribosomal protein S13 signature. 124 137 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1126 9193b6cdf72b55bde411bdc08ae43ec6 396 Pfam PF04165 Protein of unknown function (DUF401) 5 389 1.4E-64 T 23-10-2018 IPR007294 Protein of unknown function DUF401 TSIB_1126 9193b6cdf72b55bde411bdc08ae43ec6 396 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 6 392 7.4E-130 T 23-10-2018 IPR005253 Conserved hypothetical protein CHP00529 TSIB_0494 938f42214b5537694f7fa49dd47f126d 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TSIB_0494 938f42214b5537694f7fa49dd47f126d 95 Gene3D G3DSA:3.30.1360.10 1 94 3.3E-33 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0494 938f42214b5537694f7fa49dd47f126d 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 20.243 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0494 938f42214b5537694f7fa49dd47f126d 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 86 9.6E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 TSIB_0494 938f42214b5537694f7fa49dd47f126d 95 SUPERFAMILY SSF55257 1 93 9.55E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Pfam PF08463 EcoEI R protein C-terminal 679 835 4.8E-17 T 23-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 SUPERFAMILY SSF52540 271 524 1.58E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 SMART SM00487 158 341 5.7E-17 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Gene3D G3DSA:3.40.50.300 332 558 2.7E-45 T 23-10-2018 TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Gene3D G3DSA:3.90.1570.30 1 137 7.8E-46 T 23-10-2018 TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Pfam PF00271 Helicase conserved C-terminal domain 407 521 2.3E-7 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 10 122 1.3E-10 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Pfam PF04851 Type III restriction enzyme, res subunit 160 315 4.1E-38 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 SUPERFAMILY SSF52540 125 349 4.8E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1610 41f4d39b726a3dde893d6fda5df8f9cc 841 Gene3D G3DSA:3.40.50.300 143 331 1.8E-64 T 23-10-2018 TSIB_0482 4fe6eccd084acd60a4d1ca57fda49ecd 281 SUPERFAMILY SSF48239 11 276 1.71E-15 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_0482 4fe6eccd084acd60a4d1ca57fda49ecd 281 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 239 259 0.25 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TSIB_0482 4fe6eccd084acd60a4d1ca57fda49ecd 281 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 12 29 6.9 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TSIB_0482 4fe6eccd084acd60a4d1ca57fda49ecd 281 PIRSF PIRSF016175 4 281 5.3E-113 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 299 322 4.5E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Pfam PF14520 Helix-hairpin-helix domain 45 99 1.2E-10 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Gene3D G3DSA:1.10.150.20 44 107 1.3E-23 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SMART SM00306 152 273 6.8E-19 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SUPERFAMILY SSF52540 322 525 3.64E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SMART SM00305 280 327 5.8E-14 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Gene3D G3DSA:3.40.50.300 108 152 7.2E-10 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SMART SM00278 77 96 230.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SMART SM00278 44 63 0.056 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Gene3D G3DSA:3.40.50.300 323 526 5.5E-63 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 154 250 6.6E-13 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Gene3D G3DSA:2.170.16.10 153 322 2.5E-61 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SUPERFAMILY SSF51294 154 322 3.79E-40 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Pfam PF14890 Intein splicing domain 172 270 3.6E-12 T 23-10-2018 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SUPERFAMILY SSF52540 90 153 3.37E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 SUPERFAMILY SSF47794 46 104 1.57E-11 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 43 526 73.22 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Pfam PF08423 Rad51 106 154 9.4E-13 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TSIB_1992 7cec9e88f0513449f43873c078f7ece1 526 Pfam PF08423 Rad51 322 526 1.1E-70 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TSIB_1579 aa1cd7924078ff309edec9014a53d5b4 270 SMART SM00986 104 239 3.9E-12 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_1579 aa1cd7924078ff309edec9014a53d5b4 270 SUPERFAMILY SSF52141 99 244 7.52E-26 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_1579 aa1cd7924078ff309edec9014a53d5b4 270 SMART SM00987 104 239 3.9E-12 T 23-10-2018 TSIB_1579 aa1cd7924078ff309edec9014a53d5b4 270 Pfam PF03167 Uracil DNA glycosylase superfamily 110 205 7.3E-21 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_1579 aa1cd7924078ff309edec9014a53d5b4 270 Gene3D G3DSA:3.40.470.10 85 246 1.0E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_0706 6d885274f5af548050211a5d6550310f 192 PIRSF PIRSF019345 3 191 4.1E-45 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSIB_0706 6d885274f5af548050211a5d6550310f 192 Gene3D G3DSA:1.10.10.10 86 162 2.2E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0706 6d885274f5af548050211a5d6550310f 192 SUPERFAMILY SSF46785 3 83 8.85E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0706 6d885274f5af548050211a5d6550310f 192 Gene3D G3DSA:1.10.10.10 2 85 2.0E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0706 6d885274f5af548050211a5d6550310f 192 SUPERFAMILY SSF46785 87 154 9.76E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0706 6d885274f5af548050211a5d6550310f 192 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 9 177 3.8E-30 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSIB_0706 6d885274f5af548050211a5d6550310f 192 Pfam PF04079 Segregation and condensation complex subunit ScpB 11 157 2.8E-35 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSIB_1930 5ff5d24d76e2f9618089c97eaa143ba5 96 SUPERFAMILY SSF101386 1 79 1.01E-20 T 23-10-2018 TSIB_1930 5ff5d24d76e2f9618089c97eaa143ba5 96 Gene3D G3DSA:1.10.287.1080 1 79 9.1E-27 T 23-10-2018 TSIB_1930 5ff5d24d76e2f9618089c97eaa143ba5 96 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 82 3.1E-13 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 SUPERFAMILY SSF54909 62 141 1.23E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 1.7E-12 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 3.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 SUPERFAMILY SSF46785 1 62 1.69E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 Gene3D G3DSA:3.30.70.920 65 141 2.5E-17 T 23-10-2018 TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 Gene3D G3DSA:1.10.10.10 1 52 1.5E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0449 f73b3b86a9b687105c5608a9a490ca50 141 SMART SM00344 2 108 3.9E-45 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 PIRSF PIRSF001338 1 163 1.1E-78 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 1.6E-73 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 Gene3D G3DSA:3.40.50.7700 1 171 1.5E-85 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 SUPERFAMILY SSF52255 3 168 3.4E-73 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 SMART SM01001 3 152 3.2E-111 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 Pfam PF00731 AIR carboxylase 4 150 1.2E-73 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSIB_1870 db685be8988eb56b2640d6193001a4b4 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 35.737 T 23-10-2018 IPR033747 Class I PurE TSIB_0782 b833ce54e51d549f550b4cd4e63352e7 225 SUPERFAMILY SSF52540 5 216 1.55E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0782 b833ce54e51d549f550b4cd4e63352e7 225 Pfam PF06745 KaiC 9 215 1.2E-15 T 23-10-2018 IPR014774 KaiC-like domain TSIB_0782 b833ce54e51d549f550b4cd4e63352e7 225 SMART SM00382 18 181 5.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0782 b833ce54e51d549f550b4cd4e63352e7 225 Gene3D G3DSA:3.40.50.300 4 225 1.9E-46 T 23-10-2018 TSIB_0353 1c79e76090b3a3330bc26a47f7671441 208 Gene3D G3DSA:3.40.50.620 9 206 9.1E-53 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0353 1c79e76090b3a3330bc26a47f7671441 208 SUPERFAMILY SSF52402 13 169 7.28E-40 T 23-10-2018 TSIB_0353 1c79e76090b3a3330bc26a47f7671441 208 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 13 202 4.1E-58 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TSIB_0253 c530a80270cc483bfd037a4a9dc7e5e2 288 Gene3D G3DSA:3.60.15.10 50 128 4.1E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0253 c530a80270cc483bfd037a4a9dc7e5e2 288 SUPERFAMILY SSF56281 16 278 3.67E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0253 c530a80270cc483bfd037a4a9dc7e5e2 288 Gene3D G3DSA:3.40.50.10890 129 191 4.1E-24 T 23-10-2018 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 33.333 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 Gene3D G3DSA:3.30.470.20 84 219 1.0E-97 T 23-10-2018 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 229 2.7E-77 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 Gene3D G3DSA:3.30.200.20 21 231 1.0E-97 T 23-10-2018 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 Pfam PF01259 SAICAR synthetase 7 228 2.7E-69 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_0065 8b65946b9836766b71e0a494f4e0c67b 233 SUPERFAMILY SSF56104 6 232 9.16E-81 T 23-10-2018 TSIB_0514 a83a32e2774ed320fec666f5224cba7d 454 Pfam PF01554 MatE 239 405 8.9E-36 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0514 a83a32e2774ed320fec666f5224cba7d 454 Pfam PF01554 MatE 15 174 4.0E-38 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0514 a83a32e2774ed320fec666f5224cba7d 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 15 421 1.1E-121 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0514 a83a32e2774ed320fec666f5224cba7d 454 PIRSF PIRSF006603 1 454 1.2E-108 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1370 07d468adccb92b3150bf8c21e17043bb 267 PIRSF PIRSF006648 3 256 1.7E-17 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_1370 07d468adccb92b3150bf8c21e17043bb 267 Pfam PF01061 ABC-2 type transporter 5 222 1.0E-13 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 Gene3D G3DSA:1.10.1670.10 12 237 8.5E-90 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 Hamap MF_01168 N-glycosylase/DNA lyase. 9 245 39.258 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 Gene3D G3DSA:1.10.340.30 30 176 8.5E-90 T 23-10-2018 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 Pfam PF09171 N-glycosylase/DNA lyase 12 234 3.9E-87 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 SUPERFAMILY SSF48150 7 241 3.85E-81 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSIB_1904 477ef751f1ef2ce1011839fafba74321 251 PIRSF PIRSF008955 1 251 5.3E-101 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 2.1E-209 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Gene3D G3DSA:3.40.50.1480 9 410 4.6E-177 T 23-10-2018 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 PIRSF PIRSF001109 1 421 1.1E-196 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 SMART SM00997 188 349 9.2E-110 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 SUPERFAMILY SSF51735 188 350 1.97E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 SMART SM00996 6 420 1.7E-140 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 416 1.2E-28 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.6E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Gene3D G3DSA:3.40.50.720 190 349 4.6E-177 T 23-10-2018 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.483 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 SUPERFAMILY SSF52283 5 421 2.49E-102 T 23-10-2018 TSIB_0659 d66624ee5589fe1e31ca254edd65d755 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 139 6.3E-35 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSIB_0859 3a38294160947591f42d40192573158e 48 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TSIB_0859 3a38294160947591f42d40192573158e 48 SUPERFAMILY SSF57667 14 43 3.56E-6 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily TSIB_0859 3a38294160947591f42d40192573158e 48 SMART SM00355 18 41 0.0093 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TSIB_0859 3a38294160947591f42d40192573158e 48 Pfam PF00096 Zinc finger, C2H2 type 18 41 2.2E-6 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TSIB_0859 3a38294160947591f42d40192573158e 48 Gene3D G3DSA:3.30.160.60 14 43 1.9E-6 T 23-10-2018 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 SUPERFAMILY SSF53383 20 426 1.02E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_2007 2f5580fda976a14952844f7743d293a5 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 PIRSF PIRSF000521 122 427 5.8E-37 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 PIRSF PIRSF000521 28 129 4.4E-4 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 Gene3D G3DSA:3.40.640.10 59 324 7.3E-146 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 Gene3D G3DSA:3.90.1150.10 5 420 7.3E-146 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_2007 2f5580fda976a14952844f7743d293a5 443 Pfam PF00202 Aminotransferase class-III 21 424 2.6E-113 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1874 1d1f4796f98bc5245d7aa54b96a9b7a0 158 SUPERFAMILY SSF47240 1 146 3.99E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1874 1d1f4796f98bc5245d7aa54b96a9b7a0 158 Gene3D G3DSA:1.20.1260.10 1 142 1.1E-28 T 23-10-2018 IPR012347 Ferritin-like TSIB_1874 1d1f4796f98bc5245d7aa54b96a9b7a0 158 Pfam PF02915 Rubrerythrin 6 137 3.5E-17 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 SUPERFAMILY SSF56235 7 206 1.93E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 Hamap MF_02113_A Proteasome subunit beta [prcB]. 5 199 34.714 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 9 192 1.3E-75 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 Gene3D G3DSA:3.60.20.10 6 207 1.5E-65 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 Pfam PF00227 Proteasome subunit 8 187 1.4E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 PRINTS PR00141 Proteasome component signature 173 184 2.8E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 PRINTS PR00141 Proteasome component signature 17 32 2.8E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 PRINTS PR00141 Proteasome component signature 137 148 2.8E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0896 24d784b50a8966d5668bdb024f62e772 207 PRINTS PR00141 Proteasome component signature 148 159 2.8E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Gene3D G3DSA:1.10.30.30 363 426 2.3E-141 T 23-10-2018 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 514 533 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.9E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Gene3D G3DSA:3.30.930.10 14 458 2.3E-141 T 23-10-2018 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 566 7.5E-222 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Pfam PF03129 Anticodon binding domain 476 566 7.8E-24 T 23-10-2018 IPR004154 Anticodon-binding TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 SUPERFAMILY SSF55681 5 479 6.64E-118 T 23-10-2018 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 SUPERFAMILY SSF52954 463 568 1.01E-32 T 23-10-2018 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Gene3D G3DSA:1.20.1430.20 84 147 2.3E-141 T 23-10-2018 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Gene3D G3DSA:3.40.50.800 474 570 6.1E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 569 47.188 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 TSIB_0954 53307b58d6ef0f8df7100d9adfa50a61 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 243 7.8E-10 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 8 336 1.0E-102 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 Gene3D G3DSA:3.30.2130.30 15 152 2.2E-5 T 23-10-2018 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 SMART SM00981 63 150 5.1E-6 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 Pfam PF02926 THUMP domain 49 149 4.4E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 SUPERFAMILY SSF143437 41 143 1.22E-7 T 23-10-2018 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 260 266 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 Gene3D G3DSA:3.40.50.150 162 338 1.1E-36 T 23-10-2018 TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 SUPERFAMILY SSF53335 158 295 2.25E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0468 84114e1a5598e0744a856b7f09d2f14f 338 Pfam PF01170 Putative RNA methylase family UPF0020 165 330 1.2E-28 T 23-10-2018 IPR000241 Putative RNA methylase domain TSIB_1772 d38f01c03cb2dbe7fe80e7033d268ee0 248 Pfam PF05971 Protein of unknown function (DUF890) 82 164 2.0E-10 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 TSIB_1772 d38f01c03cb2dbe7fe80e7033d268ee0 248 Gene3D G3DSA:3.40.50.150 66 248 1.8E-36 T 23-10-2018 TSIB_1772 d38f01c03cb2dbe7fe80e7033d268ee0 248 SUPERFAMILY SSF53335 9 232 7.01E-23 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1918 e8ce7afe4dadec02637c1023b1c960d7 166 SUPERFAMILY SSF55021 106 164 1.13E-8 T 23-10-2018 TSIB_1918 e8ce7afe4dadec02637c1023b1c960d7 166 Pfam PF01842 ACT domain 106 158 3.2E-7 T 23-10-2018 IPR002912 ACT domain TSIB_1918 e8ce7afe4dadec02637c1023b1c960d7 166 Gene3D G3DSA:3.30.70.260 104 165 4.2E-5 T 23-10-2018 TSIB_1918 e8ce7afe4dadec02637c1023b1c960d7 166 PIRSF PIRSF004897 1 166 2.5E-71 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TSIB_0464 b8dc896a6f0a0892f194618a8ccbd897 197 Gene3D G3DSA:3.20.20.70 1 197 1.5E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0464 b8dc896a6f0a0892f194618a8ccbd897 197 Pfam PF02581 Thiamine monophosphate synthase 2 175 9.2E-61 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0464 b8dc896a6f0a0892f194618a8ccbd897 197 SUPERFAMILY SSF51391 2 193 1.57E-63 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0464 b8dc896a6f0a0892f194618a8ccbd897 197 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 2 187 1.9E-62 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0464 b8dc896a6f0a0892f194618a8ccbd897 197 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 1 193 26.459 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 163 184 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 SUPERFAMILY SSF56053 15 92 2.88E-21 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 9 185 38.141 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 Gene3D G3DSA:3.90.930.12 93 189 6.2E-37 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 PIRSF PIRSF002162 12 189 6.9E-40 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 Gene3D G3DSA:3.90.930.12 13 92 9.5E-28 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 15 184 1.3E-75 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 SUPERFAMILY SSF56053 93 184 3.93E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 Pfam PF00347 Ribosomal protein L6 20 92 1.9E-17 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0305 c33ece7ff4ab5e653c37a8ce313e7377 191 Pfam PF00347 Ribosomal protein L6 104 178 1.1E-14 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0885 97b452f384736356a06336badb5cde73 560 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 248 256 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TSIB_0885 97b452f384736356a06336badb5cde73 560 Gene3D G3DSA:3.30.470.30 222 422 2.1E-76 T 23-10-2018 TSIB_0885 97b452f384736356a06336badb5cde73 560 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 535 1.3E-22 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TSIB_0885 97b452f384736356a06336badb5cde73 560 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 399 423 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TSIB_0885 97b452f384736356a06336badb5cde73 560 Gene3D G3DSA:2.40.50.140 423 560 3.4E-54 T 23-10-2018 TSIB_0885 97b452f384736356a06336badb5cde73 560 Gene3D G3DSA:1.10.3260.10 1 221 1.4E-79 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TSIB_0885 97b452f384736356a06336badb5cde73 560 SUPERFAMILY SSF56091 220 423 1.73E-53 T 23-10-2018 TSIB_0885 97b452f384736356a06336badb5cde73 560 Pfam PF01068 ATP dependent DNA ligase domain 225 423 7.0E-65 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TSIB_0885 97b452f384736356a06336badb5cde73 560 Pfam PF04675 DNA ligase N terminus 3 177 1.1E-39 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 TSIB_0885 97b452f384736356a06336badb5cde73 560 Hamap MF_00407 DNA ligase [lig]. 1 551 34.483 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 TSIB_0885 97b452f384736356a06336badb5cde73 560 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 58 551 3.7E-165 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 TSIB_0885 97b452f384736356a06336badb5cde73 560 SUPERFAMILY SSF117018 2 243 4.58E-67 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TSIB_0885 97b452f384736356a06336badb5cde73 560 SUPERFAMILY SSF50249 427 553 1.48E-40 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 2.7E-70 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 SUPERFAMILY SSF52283 1 135 4.54E-41 T 23-10-2018 TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 Gene3D G3DSA:3.40.50.720 98 290 2.8E-143 T 23-10-2018 TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 3.8E-41 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 Gene3D G3DSA:3.40.50.720 4 317 2.8E-143 T 23-10-2018 TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 SUPERFAMILY SSF51735 103 290 1.5E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1280 01864b072bc6215af19ba0353b0f8acc 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSIB_0313 309deed3b71ce022cf541c31b08cf3ca 196 SUPERFAMILY SSF52540 1 188 2.46E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0313 309deed3b71ce022cf541c31b08cf3ca 196 Pfam PF13207 AAA domain 8 145 7.0E-33 T 23-10-2018 TSIB_0313 309deed3b71ce022cf541c31b08cf3ca 196 Gene3D G3DSA:3.40.50.300 3 189 3.9E-54 T 23-10-2018 TSIB_0313 309deed3b71ce022cf541c31b08cf3ca 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 43.295 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 552 35.312 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 SMART SM00874 281 349 3.3E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Gene3D G3DSA:3.30.56.10 280 349 3.0E-25 T 23-10-2018 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 SUPERFAMILY SSF46955 282 353 2.93E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Pfam PF03484 tRNA synthetase B5 domain 285 349 2.5E-13 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Gene3D G3DSA:3.30.930.10 368 555 6.8E-50 T 23-10-2018 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 SUPERFAMILY SSF55681 346 554 1.29E-46 T 23-10-2018 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 551 1.1E-178 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Pfam PF01409 tRNA synthetases class II core domain (F) 362 547 1.5E-4 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Pfam PF03483 B3/4 domain 119 245 1.3E-13 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 SMART SM00873 100 260 2.7E-19 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Gene3D G3DSA:3.30.56.10 1 80 3.2E-20 T 23-10-2018 TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 SUPERFAMILY SSF46955 6 75 2.11E-7 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TSIB_0617 0c9f313b4016ff15468c4be2b239aeaa 560 Gene3D G3DSA:3.50.40.10 81 279 1.6E-72 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 SMART SM00998 360 439 1.2E-32 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 4.8E-12 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 4.8E-12 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 4.8E-12 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 4.8E-12 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 Gene3D G3DSA:1.20.200.10 101 358 2.1E-95 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 SUPERFAMILY SSF48557 4 444 8.64E-135 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 3.0E-182 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 Pfam PF00206 Lyase 15 295 2.2E-58 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 6.1E-28 T 23-10-2018 IPR000362 Fumarate lyase family TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 6.1E-28 T 23-10-2018 IPR000362 Fumarate lyase family TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 6.1E-28 T 23-10-2018 IPR000362 Fumarate lyase family TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 6.1E-28 T 23-10-2018 IPR000362 Fumarate lyase family TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 8.2E-20 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 Gene3D G3DSA:1.10.40.30 359 449 1.5E-23 T 23-10-2018 TSIB_1198 0eca089fe93a9a6888e1076a60cbead7 451 Gene3D G3DSA:1.10.275.10 1 100 1.8E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal TSIB_1693 c260d8bebebda9b6d55d32588dc2f596 247 SUPERFAMILY SSF52540 2 222 5.74E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1693 c260d8bebebda9b6d55d32588dc2f596 247 Pfam PF00005 ABC transporter 17 160 1.5E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1693 c260d8bebebda9b6d55d32588dc2f596 247 SMART SM00382 26 214 5.6E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1693 c260d8bebebda9b6d55d32588dc2f596 247 Gene3D G3DSA:3.40.50.300 1 228 2.2E-52 T 23-10-2018 TSIB_1693 c260d8bebebda9b6d55d32588dc2f596 247 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 Pfam PF09183 Domain of unknown function (DUF1947) 4 74 7.5E-6 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 51 162 8.7E-32 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 Gene3D G3DSA:2.30.130.10 77 169 5.9E-36 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 4 167 3.0E-53 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 Pfam PF01472 PUA domain 87 159 3.2E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 SMART SM00359 86 161 2.1E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 PIRSF PIRSF005067 1 170 3.6E-43 T 23-10-2018 IPR016437 MCT-1/Tma20 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 Gene3D G3DSA:3.10.450.120 1 76 2.5E-24 T 23-10-2018 TSIB_1333 227c9e901d0a0f99b67e58d2f65c9f44 170 SUPERFAMILY SSF88697 85 167 1.93E-23 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_0109 0f72b45494417656e1171b278a80152a 195 SMART SM00849 4 159 7.8E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0109 0f72b45494417656e1171b278a80152a 195 SUPERFAMILY SSF56281 3 181 2.95E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0109 0f72b45494417656e1171b278a80152a 195 Gene3D G3DSA:3.60.15.10 1 195 3.3E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0109 0f72b45494417656e1171b278a80152a 195 Pfam PF13483 Beta-lactamase superfamily domain 2 159 6.8E-22 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1159 20.924 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 630 1.1E-31 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1157 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SUPERFAMILY SSF52540 4 289 1.06E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1149 9.4E-64 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Gene3D G3DSA:3.30.70.1620 581 657 1.3E-43 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 PIRSF PIRSF005719 1 1165 3.8E-278 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 4 1157 5.3E-228 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SUPERFAMILY SSF57997 667 911 6.47E-8 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Gene3D G3DSA:1.20.1060.20 512 669 1.3E-43 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SUPERFAMILY SSF52540 918 1160 3.55E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Gene3D G3DSA:1.20.5.340 769 875 6.8E-7 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Gene3D G3DSA:3.40.50.300 2 233 1.9E-59 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SMART SM00968 520 631 8.7E-41 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SUPERFAMILY SSF75553 480 670 4.58E-48 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 SUPERFAMILY SSF57997 296 510 6.21E-8 T 23-10-2018 TSIB_0722 37e3b13b0f5bdfd121720e51682c4058 1177 Gene3D G3DSA:3.40.50.300 1005 1176 2.0E-59 T 23-10-2018 TSIB_1200 5a803edf1dd405bc2bdc60b0ccba61ad 199 Pfam PF12840 Helix-turn-helix domain 15 68 9.3E-13 T 23-10-2018 TSIB_1200 5a803edf1dd405bc2bdc60b0ccba61ad 199 SUPERFAMILY SSF46785 7 98 5.46E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1200 5a803edf1dd405bc2bdc60b0ccba61ad 199 Gene3D G3DSA:1.10.10.10 8 92 9.5E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1200 5a803edf1dd405bc2bdc60b0ccba61ad 199 SMART SM00418 15 82 0.0065 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 PIRSF PIRSF005644 1 336 2.4E-126 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 Gene3D G3DSA:3.90.650.10 154 336 5.9E-55 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 SUPERFAMILY SSF55326 3 152 1.2E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 2 336 3.7E-121 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 308 2.9E-30 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 149 9.4E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 SUPERFAMILY SSF56042 154 330 1.02E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_1499 1b3d8107589ffe3db6a9ed3f2d584a9f 336 Gene3D G3DSA:3.30.1330.10 1 153 8.9E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 305 2.0E-47 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 Gene3D G3DSA:3.30.230.10 16 143 3.4E-9 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 SUPERFAMILY SSF54211 19 147 4.55E-15 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 Pfam PF00288 GHMP kinases N terminal domain 76 136 1.7E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 Pfam PF08544 GHMP kinases C terminal 203 283 5.5E-6 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TSIB_0667 1ca7e558d2b42144b2957b7caab80ac0 323 PIRSF PIRSF004884 1 309 7.8E-98 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 SUPERFAMILY SSF52540 359 543 4.1E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 SMART SM00382 375 517 0.003 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 SMART SM00534 376 564 8.2E-24 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 PIRSF PIRSF029254 1 565 1.5E-188 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 Pfam PF00488 MutS domain V 379 461 5.5E-8 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 1 563 24.482 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TSIB_1545 f7bae5f4dc0a5c95666852dada3f9c9e 565 Gene3D G3DSA:3.40.50.300 337 547 6.0E-22 T 23-10-2018 TSIB_1667 382f1b78480835f3cec09d943cbd6e0b 310 SMART SM00729 55 252 4.2E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1667 382f1b78480835f3cec09d943cbd6e0b 310 Gene3D G3DSA:3.20.20.70 46 302 1.6E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1667 382f1b78480835f3cec09d943cbd6e0b 310 SUPERFAMILY SSF102114 59 261 6.54E-30 T 23-10-2018 TSIB_1667 382f1b78480835f3cec09d943cbd6e0b 310 Pfam PF04055 Radical SAM superfamily 60 209 8.6E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 SUPERFAMILY SSF56300 395 622 2.28E-19 T 23-10-2018 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 396 598 3.2E-15 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 PIRSF PIRSF000803 30 658 1.7E-185 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 Hamap MF_00325 DNA polymerase II small subunit [polB]. 3 651 32.981 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 Gene3D G3DSA:3.60.21.50 381 632 5.2E-25 T 23-10-2018 TSIB_1589 dafd6154acdf5f31c8e4fe6610d046fb 660 Gene3D G3DSA:1.10.8.800 1 70 1.1E-30 T 23-10-2018 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 PRINTS PR00340 P-II protein signature 78 98 6.2E-22 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 PRINTS PR00340 P-II protein signature 5 20 6.2E-22 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 PRINTS PR00340 P-II protein signature 47 70 6.2E-22 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 Pfam PF00543 Nitrogen regulatory protein P-II 7 100 8.5E-29 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 SUPERFAMILY SSF54913 4 107 1.24E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 SMART SM00938 7 100 1.1E-38 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSIB_1114 2327611c16b8d9420f6d6a31622578f6 108 Gene3D G3DSA:3.30.70.120 3 108 7.7E-38 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 17 73 2.7E-8 T 23-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 518 527 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 238 250 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 375 390 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 166 179 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 498 515 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 PRINTS PR00379 Intein signature 348 360 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Gene3D G3DSA:3.40.50.300 5 183 4.5E-28 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Gene3D G3DSA:3.40.50.300 418 608 3.6E-25 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SUPERFAMILY SSF55608 234 319 9.35E-5 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Gene3D G3DSA:1.10.8.60 609 672 3.8E-26 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Gene3D G3DSA:1.20.272.10 673 766 4.2E-36 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SUPERFAMILY SSF52540 16 674 4.22E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Pfam PF08542 Replication factor C C-terminal domain 674 759 4.7E-20 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Pfam PF13177 DNA polymerase III, delta subunit 526 608 1.8E-10 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 500 524 3.0E-4 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Pfam PF14528 LAGLIDADG-like domain 240 319 8.8E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SUPERFAMILY SSF55608 330 408 9.07E-11 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SMART SM00382 48 615 9.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Pfam PF14890 Intein splicing domain 127 523 1.3E-20 T 23-10-2018 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SUPERFAMILY SSF51294 88 524 1.75E-24 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 89 179 4.5E-8 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 Gene3D G3DSA:3.10.28.10 234 406 3.5E-24 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SMART SM00305 481 529 5.3E-9 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SMART SM00306 86 203 3.1E-15 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0101 98052395cc022f649e5220e8d8b7302d 766 SUPERFAMILY SSF48019 674 762 5.1E-22 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSIB_1524 e908c98d503141e6468036ca10d86fae 223 Gene3D G3DSA:3.40.50.11570 4 218 3.4E-62 T 23-10-2018 TSIB_1524 e908c98d503141e6468036ca10d86fae 223 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 213 1.7E-70 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_2016 f374bef04a75fb1516c45c6314cdfb85 145 SUPERFAMILY SSF81593 72 141 1.15E-7 T 23-10-2018 TSIB_2016 f374bef04a75fb1516c45c6314cdfb85 145 Pfam PF01934 Protein of unknown function DUF86 23 139 1.9E-32 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TSIB_2016 f374bef04a75fb1516c45c6314cdfb85 145 Gene3D G3DSA:1.20.120.580 7 145 8.1E-27 T 23-10-2018 IPR037038 Bsu32300-like superfamily TSIB_1188 f4470c03f129badfca1c2bec4ab8ade8 498 SUPERFAMILY SSF48239 55 454 4.91E-17 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_1188 f4470c03f129badfca1c2bec4ab8ade8 498 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 58 160 5.2E-7 T 23-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TSIB_1188 f4470c03f129badfca1c2bec4ab8ade8 498 Gene3D G3DSA:1.50.10.20 35 171 2.5E-14 T 23-10-2018 TSIB_1913 d7549967cfa71b6c06abc34a01901c27 241 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 102 225 3.5E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:1.10.8.60 381 402 1.4E-83 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 250 379 5.7E-52 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 585 714 1.2E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:3.40.50.300 539 714 3.5E-74 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SUPERFAMILY SSF52540 208 534 8.14E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SUPERFAMILY SSF50692 12 99 5.22E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SMART SM01073 16 100 2.3E-37 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 15 825 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 ProSitePatterns PS00674 AAA-protein family signature. 685 703 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 ProSitePatterns PS00674 AAA-protein family signature. 350 368 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SUPERFAMILY SSF54585 100 215 2.29E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 16 100 4.1E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:2.40.40.20 10 100 4.5E-33 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SMART SM00382 246 382 6.6E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SMART SM00382 581 717 9.7E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 123 202 6.0E-13 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SMART SM01072 118 202 3.8E-16 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:1.10.8.60 444 537 4.2E-17 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:3.40.50.300 208 380 1.4E-83 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 Gene3D G3DSA:1.10.8.60 716 824 1.1E-29 T 23-10-2018 TSIB_1393 15ca822d073f68d0889fcb4af813b46a 839 SUPERFAMILY SSF52540 543 820 7.36E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0538 63dd27a9d520167069bdd93926f21def 442 SUPERFAMILY SSF111283 3 438 3.01E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSIB_0538 63dd27a9d520167069bdd93926f21def 442 Pfam PF01523 Putative modulator of DNA gyrase 21 304 6.3E-48 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSIB_0538 63dd27a9d520167069bdd93926f21def 442 Gene3D G3DSA:3.30.2290.10 3 210 2.4E-14 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSIB_0315 c2180c1f583e842a3242c112d035350c 88 Pfam PF01199 Ribosomal protein L34e 4 82 4.5E-22 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 PRINTS PR01250 Ribosomal protein L34 signature 56 78 1.1E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 PRINTS PR01250 Ribosomal protein L34 signature 18 35 1.1E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 PRINTS PR01250 Ribosomal protein L34 signature 5 18 1.1E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 PRINTS PR01250 Ribosomal protein L34 signature 36 46 1.1E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 Gene3D G3DSA:3.40.1800.40 29 86 1.1E-8 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0315 c2180c1f583e842a3242c112d035350c 88 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 27.429 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1535 62ab8fd7a7d159192fd06b244e755089 137 PIRSF PIRSF018867 15 134 3.8E-36 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit TSIB_1535 62ab8fd7a7d159192fd06b244e755089 137 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 17 97 1.2E-16 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TSIB_1535 62ab8fd7a7d159192fd06b244e755089 137 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 19 94 3.7E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 SUPERFAMILY SSF53187 7 342 1.23E-60 T 23-10-2018 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 Gene3D G3DSA:3.40.630.10 11 336 1.6E-132 T 23-10-2018 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 SUPERFAMILY SSF101821 71 179 1.83E-29 T 23-10-2018 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 PIRSF PIRSF001123 3 347 1.2E-104 T 23-10-2018 IPR008007 Peptidase M42 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 Gene3D G3DSA:2.40.30.40 71 163 1.6E-132 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TSIB_1509 e43c42a806bda25f112bf41deebcccf4 348 Pfam PF05343 M42 glutamyl aminopeptidase 48 333 8.8E-101 T 23-10-2018 IPR008007 Peptidase M42 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 SUPERFAMILY SSF51905 5 365 5.12E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 Pfam PF02910 Fumarate reductase flavoprotein C-term 423 451 2.5E-5 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.2E-6 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 175 7.2E-6 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 325 332 7.2E-6 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 Gene3D G3DSA:3.90.700.10 212 302 2.0E-107 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 SUPERFAMILY SSF56425 204 307 3.74E-32 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 Gene3D G3DSA:1.20.58.100 361 460 9.2E-19 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 447 2.1E-150 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 SUPERFAMILY SSF46977 385 453 3.27E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 310 332 2.4E-11 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.4E-11 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.4E-11 T 23-10-2018 TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 Gene3D G3DSA:3.50.50.60 5 354 2.0E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0055 f333b3354b1eb7acfe174f0c4a06ea0c 461 Pfam PF00890 FAD binding domain 5 347 2.1E-64 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 Pfam PF02540 NAD synthase 10 89 3.5E-7 T 23-10-2018 IPR022310 NAD/GMP synthase TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 SUPERFAMILY SSF52402 8 230 8.82E-54 T 23-10-2018 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 Pfam PF00958 GMP synthase C terminal domain 223 312 2.4E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 SUPERFAMILY SSF54810 195 313 1.24E-44 T 23-10-2018 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 Gene3D G3DSA:3.30.300.10 196 313 2.0E-52 T 23-10-2018 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 10 313 4.6E-149 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 6 313 46.522 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TSIB_0047 6dfeb50c42be763ac9a4ea65724400a4 313 Gene3D G3DSA:3.40.50.620 8 195 3.0E-77 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 SUPERFAMILY SSF82114 87 209 5.89E-41 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.2E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.2E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 51 7.7E-7 T 23-10-2018 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 SUPERFAMILY SSF46785 4 79 5.47E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 25.144 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 Gene3D G3DSA:1.10.10.10 1 84 4.5E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 Gene3D G3DSA:2.40.30.30 86 211 2.7E-42 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 SMART SM00419 14 63 8.3E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSIB_0978 a98970c23b76296c829c4f7fac633a31 211 Pfam PF01982 Domain of unknown function DUF120 92 209 4.6E-40 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TSIB_0205 2534adc0669b6da725177642c4ddb25a 139 Pfam PF07366 SnoaL-like polyketide cyclase 8 133 3.7E-38 T 23-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 TSIB_0205 2534adc0669b6da725177642c4ddb25a 139 Gene3D G3DSA:3.10.450.50 1 138 1.8E-43 T 23-10-2018 TSIB_0205 2534adc0669b6da725177642c4ddb25a 139 SUPERFAMILY SSF54427 2 137 2.84E-40 T 23-10-2018 IPR032710 NTF2-like domain superfamily TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 Gene3D G3DSA:3.50.50.60 21 320 1.2E-113 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 3.5E-40 T 23-10-2018 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 3.5E-40 T 23-10-2018 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 3.5E-40 T 23-10-2018 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 3.5E-40 T 23-10-2018 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 23 42 3.5E-40 T 23-10-2018 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 22 324 7.5E-120 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 54 69 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 162 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 75 85 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 216 232 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 306 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 22 44 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 136 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 275 5.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 Gene3D G3DSA:3.50.50.60 139 260 1.2E-113 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 22 313 9.0E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 SUPERFAMILY SSF51905 16 323 2.11E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1151 909ff0557f2a2b3ab4eb54a52cc5e877 334 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 157 177 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 Gene3D G3DSA:2.40.30.130 13 84 6.4E-31 T 23-10-2018 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 SMART SM00863 166 209 5.3E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 SUPERFAMILY SSF55186 85 211 2.49E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 Gene3D G3DSA:3.30.980.10 85 213 1.3E-46 T 23-10-2018 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 Pfam PF01411 tRNA synthetases class II (A) 13 88 1.9E-12 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 209 3.5E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_0225 1f6496ac31b9e807e4077f008fba69b5 213 SUPERFAMILY SSF50447 1 83 2.01E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 SUPERFAMILY SSF52402 3 235 7.94E-49 T 23-10-2018 TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 PIRSF PIRSF006293 2 239 1.5E-68 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 220 2.5E-49 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 Pfam PF06508 Queuosine biosynthesis protein QueC 5 225 2.5E-62 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 233 43.925 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSIB_1155 d653a813ca003577e35feed8f84d3bae 241 Gene3D G3DSA:3.40.50.620 3 237 1.8E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0948 b60838f3fcbf0b577e41f65f3583d86b 575 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 356 565 4.0E-7 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TSIB_0948 b60838f3fcbf0b577e41f65f3583d86b 575 SUPERFAMILY SSF56219 348 572 1.06E-28 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSIB_0948 b60838f3fcbf0b577e41f65f3583d86b 575 Gene3D G3DSA:3.60.10.10 350 573 1.9E-29 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSIB_1627 84bd68b3ac6d9ca41b672b1b2629c3dc 160 Pfam PF13247 4Fe-4S dicluster domain 51 134 6.1E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1627 84bd68b3ac6d9ca41b672b1b2629c3dc 160 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1627 84bd68b3ac6d9ca41b672b1b2629c3dc 160 Gene3D G3DSA:3.30.70.20 59 112 1.3E-21 T 23-10-2018 TSIB_1627 84bd68b3ac6d9ca41b672b1b2629c3dc 160 SUPERFAMILY SSF54862 5 135 1.56E-35 T 23-10-2018 TSIB_1627 84bd68b3ac6d9ca41b672b1b2629c3dc 160 Gene3D G3DSA:3.30.70.20 6 141 1.3E-21 T 23-10-2018 TSIB_0403 f8682ca470f067ca2a6ceac0583a0a1e 66 Gene3D G3DSA:2.20.28.70 13 62 8.5E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TSIB_0403 f8682ca470f067ca2a6ceac0583a0a1e 66 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 16 61 19.049 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 TSIB_0403 f8682ca470f067ca2a6ceac0583a0a1e 66 SUPERFAMILY SSF57829 12 60 2.93E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSIB_0403 f8682ca470f067ca2a6ceac0583a0a1e 66 SMART SM01377 12 60 4.3E-11 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 24 230 3.6E-55 T 23-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 181 213 3.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 3.7E-6 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 Gene3D G3DSA:2.160.10.10 113 238 1.2E-28 T 23-10-2018 TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 SUPERFAMILY SSF51161 18 233 2.22E-40 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_2054 77f3556447c3d5fe01c3a57df6da2185 247 Gene3D G3DSA:3.40.50.20 19 112 5.1E-6 T 23-10-2018 TSIB_0832 c9cbb3f0fb5a3855e00f2f3712a32c43 373 Gene3D G3DSA:3.40.50.10330 79 202 2.7E-5 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSIB_0832 c9cbb3f0fb5a3855e00f2f3712a32c43 373 Pfam PF01513 ATP-NAD kinase 4 372 2.4E-43 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSIB_0832 c9cbb3f0fb5a3855e00f2f3712a32c43 373 PIRSF PIRSF016907 1 373 2.2E-143 T 23-10-2018 IPR011386 Putative ATP-NAD kinase TSIB_0832 c9cbb3f0fb5a3855e00f2f3712a32c43 373 SUPERFAMILY SSF111331 104 146 6.1E-6 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 61 85 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 SUPERFAMILY SSF53613 25 296 1.64E-61 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 Gene3D G3DSA:3.40.1190.20 21 310 7.9E-64 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 Pfam PF00294 pfkB family carbohydrate kinase 26 295 1.7E-48 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 PRINTS PR00990 Ribokinase signature 29 50 5.0E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 PRINTS PR00990 Ribokinase signature 187 202 5.0E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 PRINTS PR00990 Ribokinase signature 56 75 5.0E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 PRINTS PR00990 Ribokinase signature 220 231 5.0E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_1368 89f07280f3f20bc5bae79fd5a31b0ebb 315 PRINTS PR00990 Ribokinase signature 126 139 5.0E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_0197 31f56369d61408ff1c157d43fd4fdfdd 512 SUPERFAMILY SSF48208 290 508 8.5E-8 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSIB_0197 31f56369d61408ff1c157d43fd4fdfdd 512 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 331 498 1.4E-42 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 SUPERFAMILY SSF56235 38 235 4.37E-38 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 PIRSF PIRSF001589 29 404 2.4E-53 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 PIRSF PIRSF001589 391 509 5.3E-20 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 Gene3D G3DSA:3.60.20.10 30 250 1.6E-44 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 Pfam PF00733 Asparagine synthase 395 483 7.2E-20 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 Pfam PF00733 Asparagine synthase 264 388 5.8E-31 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 SUPERFAMILY SSF52402 259 488 5.95E-57 T 23-10-2018 TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 Pfam PF13537 Glutamine amidotransferase domain 89 207 1.3E-25 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 Gene3D G3DSA:3.40.50.620 259 509 8.2E-72 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1407 933b4db028aaf4a269ec4b80ca72fec9 509 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 30 393 2.3E-81 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 36 303 1.1E-95 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 80 94 3.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 109 119 3.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 303 3.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 241 3.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 175 187 3.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 Gene3D G3DSA:3.40.50.150 98 304 2.5E-71 T 23-10-2018 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 Pfam PF01189 16S rRNA methyltransferase RsmB/F 98 301 1.3E-53 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 94 2.3E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 Gene3D G3DSA:3.30.70.3130 1 93 5.3E-17 T 23-10-2018 TSIB_1554 98747592dbead5b0e770a5cd4bf83b5f 304 SUPERFAMILY SSF53335 19 303 4.14E-62 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1090 ed163386ff054817fe2432050a4470d4 120 Pfam PF04266 ASCH domain 7 108 7.3E-12 T 23-10-2018 IPR007374 ASCH domain TSIB_1090 ed163386ff054817fe2432050a4470d4 120 SMART SM01022 6 109 1.5E-6 T 23-10-2018 IPR007374 ASCH domain TSIB_1090 ed163386ff054817fe2432050a4470d4 120 PIRSF PIRSF016134 2 111 3.3E-43 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TSIB_1090 ed163386ff054817fe2432050a4470d4 120 Gene3D G3DSA:2.30.130.30 1 113 5.2E-40 T 23-10-2018 TSIB_1090 ed163386ff054817fe2432050a4470d4 120 SUPERFAMILY SSF88697 1 109 3.23E-31 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 SMART SM00195 32 145 8.7E-9 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 SUPERFAMILY SSF52799 6 147 4.76E-33 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 Gene3D G3DSA:3.90.190.10 4 149 7.1E-33 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 SMART SM00404 54 145 1.1E-7 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 90 100 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 TSIB_1060 a02dd38ca5b80dd4b848aa682ba1b915 149 Pfam PF00782 Dual specificity phosphatase, catalytic domain 42 144 3.5E-19 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 TSIB_1244 8c91e4b6c8b7ed99c40e26df80b9022b 366 SUPERFAMILY SSF102114 23 332 7.32E-45 T 23-10-2018 TSIB_1244 8c91e4b6c8b7ed99c40e26df80b9022b 366 Pfam PF13353 4Fe-4S single cluster domain 30 128 1.3E-7 T 23-10-2018 TSIB_1244 8c91e4b6c8b7ed99c40e26df80b9022b 366 Pfam PF04055 Radical SAM superfamily 27 198 1.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1244 8c91e4b6c8b7ed99c40e26df80b9022b 366 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 264 340 5.6E-14 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1244 8c91e4b6c8b7ed99c40e26df80b9022b 366 Gene3D G3DSA:3.20.20.70 19 364 3.7E-60 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1537 afb38167778a8bb68ef1353f20089f7d 377 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 23 375 2.1E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TSIB_1537 afb38167778a8bb68ef1353f20089f7d 377 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 22 371 1.2E-155 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TSIB_1537 afb38167778a8bb68ef1353f20089f7d 377 PIRSF PIRSF015658 1 377 2.7E-169 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 139 2.9E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 SUPERFAMILY SSF56042 145 316 4.49E-40 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 SUPERFAMILY SSF55326 4 143 2.97E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 PIRSF PIRSF005644 1 329 1.6E-92 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 Gene3D G3DSA:3.90.650.10 145 329 1.5E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 310 2.9E-32 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_0767 d47c2ef83659d1649ae6d3162606de1a 329 Gene3D G3DSA:3.30.1330.10 2 140 4.3E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0259 e28a0163276b8eb9283b307c145891e4 417 SUPERFAMILY SSF52540 14 150 1.58E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 127 2.5E-19 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 SUPERFAMILY SSF53092 11 127 6.98E-27 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 SUPERFAMILY SSF55920 126 350 1.44E-82 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 Gene3D G3DSA:3.40.350.10 4 125 1.6E-29 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 Gene3D G3DSA:3.90.230.10 126 351 1.1E-89 T 23-10-2018 TSIB_1026 219f46fc8eef5d47a9ebe3faf1072cfe 351 Pfam PF00557 Metallopeptidase family M24 135 336 3.0E-69 T 23-10-2018 IPR000994 Peptidase M24 TSIB_0727 7abbacf30d4f9ccc5052a078ff0e1cb2 142 PIRSF PIRSF006595 1 142 9.3E-48 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TSIB_0727 7abbacf30d4f9ccc5052a078ff0e1cb2 142 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 1 141 5.0E-52 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TSIB_0727 7abbacf30d4f9ccc5052a078ff0e1cb2 142 Pfam PF03684 Uncharacterised protein family (UPF0179) 2 137 1.9E-41 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TSIB_0727 7abbacf30d4f9ccc5052a078ff0e1cb2 142 Hamap MF_00498 UPF0179 protein . 1 139 22.3 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 Pfam PF01163 RIO1 family 111 291 9.9E-47 T 23-10-2018 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 SMART SM00090 68 298 7.6E-73 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 Gene3D G3DSA:1.10.510.10 202 297 2.0E-16 T 23-10-2018 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 SUPERFAMILY SSF46785 8 94 1.14E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 Gene3D G3DSA:3.30.200.20 97 195 1.5E-30 T 23-10-2018 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 Pfam PF09202 Rio2, N-terminal 13 93 2.4E-24 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 Gene3D G3DSA:1.10.10.10 5 94 5.7E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0280 4b7ee421afb764534454e1d1b9ed920b 307 SUPERFAMILY SSF56112 102 272 1.07E-27 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TSIB_0547 3b5d3018a46db2b76797f39b70307948 203 Pfam PF02676 Methyltransferase TYW3 4 185 9.1E-39 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_0547 3b5d3018a46db2b76797f39b70307948 203 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 187 26.531 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TSIB_0547 3b5d3018a46db2b76797f39b70307948 203 Gene3D G3DSA:3.30.1960.10 1 185 1.2E-49 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_0547 3b5d3018a46db2b76797f39b70307948 203 SUPERFAMILY SSF111278 2 184 1.16E-48 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_0561 3838b9b96ed8709613b1c6aa8dfc83e9 224 SUPERFAMILY SSF51366 61 210 5.81E-7 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSIB_0561 3838b9b96ed8709613b1c6aa8dfc83e9 224 Gene3D G3DSA:3.40.50.1860 6 207 3.9E-90 T 23-10-2018 TSIB_0561 3838b9b96ed8709613b1c6aa8dfc83e9 224 Gene3D G3DSA:3.40.50.1860 102 202 3.9E-90 T 23-10-2018 TSIB_0561 3838b9b96ed8709613b1c6aa8dfc83e9 224 Pfam PF01177 Asp/Glu/Hydantoin racemase 43 203 6.3E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_0212 7e784fb4ea3069c8b579ddb9058b6583 158 Pfam PF03551 Transcriptional regulator PadR-like family 21 90 4.7E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSIB_0212 7e784fb4ea3069c8b579ddb9058b6583 158 SUPERFAMILY SSF46785 17 145 1.36E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0212 7e784fb4ea3069c8b579ddb9058b6583 158 Gene3D G3DSA:1.10.10.10 3 111 1.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0647 bde8f3c97cb864a626a5f27ece7f8805 78 SUPERFAMILY SSF160374 1 73 1.31E-23 T 23-10-2018 TSIB_0647 bde8f3c97cb864a626a5f27ece7f8805 78 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 1.1E-10 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0647 bde8f3c97cb864a626a5f27ece7f8805 78 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 19.803 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0647 bde8f3c97cb864a626a5f27ece7f8805 78 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 51 3.0E-13 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 TSIB_0647 bde8f3c97cb864a626a5f27ece7f8805 78 Gene3D G3DSA:3.10.20.10 3 77 1.4E-26 T 23-10-2018 TSIB_1176 f31c2c59db8e05b311fba6070a87c0b6 170 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 1 165 1.2E-49 T 23-10-2018 IPR005268 Conserved hypothetical protein CHP00725 TSIB_1176 f31c2c59db8e05b311fba6070a87c0b6 170 SUPERFAMILY SSF102405 1 164 8.85E-33 T 23-10-2018 TSIB_1176 f31c2c59db8e05b311fba6070a87c0b6 170 Pfam PF03641 Possible lysine decarboxylase 47 117 4.4E-7 T 23-10-2018 IPR031100 LOG family TSIB_1176 f31c2c59db8e05b311fba6070a87c0b6 170 Gene3D G3DSA:3.40.50.450 1 167 8.6E-36 T 23-10-2018 TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 SUPERFAMILY SSF51735 8 258 2.35E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.1E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.1E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.1E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.1E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.1E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 8.8E-49 T 23-10-2018 TSIB_0703 05d9cdada4dc3941cfc2f38c095d2a58 263 Gene3D G3DSA:3.40.50.720 1 262 3.6E-63 T 23-10-2018 TSIB_0352 d870f25682fccb310a5928ae1a4641bc 178 Pfam PF06197 Protein of unknown function (DUF998) 16 174 3.4E-16 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TSIB_0141 ffacf1898bf6b53e3100edfdb48fb992 106 Pfam PF00005 ABC transporter 1 103 6.7E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0141 ffacf1898bf6b53e3100edfdb48fb992 106 SUPERFAMILY SSF52540 1 99 1.24E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0141 ffacf1898bf6b53e3100edfdb48fb992 106 Gene3D G3DSA:3.40.50.300 1 104 5.5E-25 T 23-10-2018 TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 141 1.8E-21 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 SMART SM00649 10 142 2.4E-65 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 Gene3D G3DSA:1.10.10.250 77 166 8.1E-36 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 Pfam PF03946 Ribosomal protein L11, N-terminal domain 10 63 1.9E-22 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 6 143 27.918 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 SUPERFAMILY SSF46906 70 142 1.83E-22 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 SUPERFAMILY SSF54747 7 86 8.9E-25 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TSIB_0382 8027387364fc346ab1038f7fb4cba9c6 166 Gene3D G3DSA:2.10.260.30 6 73 2.6E-27 T 23-10-2018 TSIB_1336 7498f23b0d6f82d117071c563262633f 241 SUPERFAMILY SSF50249 135 224 1.27E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1336 7498f23b0d6f82d117071c563262633f 241 Gene3D G3DSA:1.20.1440.150 1 124 2.9E-56 T 23-10-2018 TSIB_1336 7498f23b0d6f82d117071c563262633f 241 Pfam PF01588 Putative tRNA binding domain 138 224 3.1E-20 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSIB_1336 7498f23b0d6f82d117071c563262633f 241 Gene3D G3DSA:2.40.50.140 125 241 2.2E-35 T 23-10-2018 TSIB_1443 57d0d9c3c1db4d8dfc581e208d0eb834 98 Gene3D G3DSA:1.20.120.460 1 98 2.6E-35 T 23-10-2018 IPR038317 Pf1176-like superfamily TSIB_1443 57d0d9c3c1db4d8dfc581e208d0eb834 98 Pfam PF11505 Protein of unknown function (DUF3216) 5 95 1.1E-33 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 SUPERFAMILY SSF51621 4 262 9.81E-103 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 259 1.2E-93 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 Gene3D G3DSA:3.20.20.60 2 274 6.1E-111 T 23-10-2018 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 PIRSF PIRSF000388 1 264 1.6E-104 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.102 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSIB_1556 ecb4c8062544c99d876756d9ef340817 288 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 2.2E-109 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 SMART SM01119 257 352 2.3E-13 T 23-10-2018 IPR026956 D-serine dehydratase-like domain TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 Gene3D G3DSA:2.40.37.20 7 365 7.2E-82 T 23-10-2018 TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 Pfam PF01168 Alanine racemase, N-terminal domain 14 242 2.3E-29 T 23-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 Pfam PF14031 Putative serine dehydratase domain 257 349 7.3E-10 T 23-10-2018 IPR026956 D-serine dehydratase-like domain TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 SUPERFAMILY SSF51419 14 243 3.05E-35 T 23-10-2018 IPR029066 PLP-binding barrel TSIB_1235 25a00dabb00486b9f6ed8823466d3536 375 Gene3D G3DSA:3.20.20.10 16 239 7.2E-82 T 23-10-2018 IPR029066 PLP-binding barrel TSIB_1065 d29e89d540e9c73ee462ccd8a104e2b6 267 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 11 262 1.5E-18 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TSIB_1065 d29e89d540e9c73ee462ccd8a104e2b6 267 Gene3D G3DSA:3.40.830.10 7 267 4.2E-71 T 23-10-2018 TSIB_1065 d29e89d540e9c73ee462ccd8a104e2b6 267 SUPERFAMILY SSF53213 10 264 4.32E-30 T 23-10-2018 TSIB_0519 5680203d543157da8095995e4d6306c3 213 Gene3D G3DSA:3.40.50.11570 2 211 9.3E-64 T 23-10-2018 TSIB_0519 5680203d543157da8095995e4d6306c3 213 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 6 210 2.6E-58 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_1700 7c3b09685264efdad7276d55f46506cb 364 Gene3D G3DSA:1.20.1530.20 2 342 1.1E-23 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_1700 7c3b09685264efdad7276d55f46506cb 364 Pfam PF01758 Sodium Bile acid symporter family 52 253 3.3E-47 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TSIB_1700 7c3b09685264efdad7276d55f46506cb 364 PIRSF PIRSF005508 1 358 4.4E-141 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TSIB_1700 7c3b09685264efdad7276d55f46506cb 364 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 6 341 2.2E-118 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 SUPERFAMILY SSF52374 102 418 9.65E-90 T 23-10-2018 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Gene3D G3DSA:2.40.240.100 412 575 4.7E-43 T 23-10-2018 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 412 562 2.0E-30 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Gene3D G3DSA:3.40.50.620 96 411 7.2E-119 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 7 576 9.8E-206 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 SUPERFAMILY SSF50715 412 573 1.36E-30 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 10 574 39.636 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 PRINTS PR00987 Glutamyl-tRNA synthetase signature 135 148 3.8E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 PRINTS PR00987 Glutamyl-tRNA synthetase signature 299 307 3.8E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 PRINTS PR00987 Glutamyl-tRNA synthetase signature 106 118 3.8E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 PRINTS PR00987 Glutamyl-tRNA synthetase signature 283 293 3.8E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 PRINTS PR00987 Glutamyl-tRNA synthetase signature 120 131 3.8E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 102 408 2.2E-82 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSIB_0534 78c5f3e38d847f277d87762a368fbb03 576 Gene3D G3DSA:2.40.240.10 421 520 4.7E-43 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 136 24.34 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 SUPERFAMILY SSF53137 11 137 8.5E-41 T 23-10-2018 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 Pfam PF00411 Ribosomal protein S11 17 135 2.6E-49 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 15 131 9.8E-68 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 PIRSF PIRSF002131 1 138 3.5E-38 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSIB_0341 be035556aaa1eff8d914a2dcbd0c5be7 139 Gene3D G3DSA:3.30.420.80 2 139 6.2E-67 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_2028 5bf5d6b94f3b62fb1301c388238eb674 366 SUPERFAMILY SSF53383 2 363 1.22E-134 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_2028 5bf5d6b94f3b62fb1301c388238eb674 366 Gene3D G3DSA:3.40.640.10 1 238 1.4E-109 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_2028 5bf5d6b94f3b62fb1301c388238eb674 366 PIRSF PIRSF000390 1 366 1.1E-132 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSIB_2028 5bf5d6b94f3b62fb1301c388238eb674 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 360 5.1E-142 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSIB_2028 5bf5d6b94f3b62fb1301c388238eb674 366 Gene3D G3DSA:3.90.1150.10 239 365 1.7E-42 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0642 4fddb85880b7c4e2e227a875d6cb6e7b 491 Pfam PF00474 Sodium:solute symporter family 36 424 4.6E-38 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSIB_0642 4fddb85880b7c4e2e227a875d6cb6e7b 491 Gene3D G3DSA:1.20.1730.10 22 483 4.9E-73 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily TSIB_1954 a95ef3ab004a41645cd8fcdd2c77bb4f 163 Gene3D G3DSA:3.10.50.80 5 154 1.6E-55 T 23-10-2018 TSIB_1954 a95ef3ab004a41645cd8fcdd2c77bb4f 163 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 150 6.1E-22 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TSIB_1954 a95ef3ab004a41645cd8fcdd2c77bb4f 163 SUPERFAMILY SSF54534 5 154 2.75E-47 T 23-10-2018 TSIB_1966 cee1d23a2f8ec113bb3727c47b8dd2c3 196 SMART SM00418 15 94 4.4E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1966 cee1d23a2f8ec113bb3727c47b8dd2c3 196 SUPERFAMILY SSF46785 7 170 3.07E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1966 cee1d23a2f8ec113bb3727c47b8dd2c3 196 Gene3D G3DSA:1.10.10.10 4 93 8.6E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1966 cee1d23a2f8ec113bb3727c47b8dd2c3 196 Gene3D G3DSA:1.10.20.10 94 195 1.3E-48 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1966 cee1d23a2f8ec113bb3727c47b8dd2c3 196 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 6.7E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1559 d6b6b670804e877a4b2940a60bb19fc5 112 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 29 102 8.0E-15 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D TSIB_1559 d6b6b670804e877a4b2940a60bb19fc5 112 Gene3D G3DSA:1.10.10.1150 41 104 7.4E-7 T 23-10-2018 TSIB_0700 888fcef2d8d54126eb36292a12c58261 146 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 2.9E-24 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSIB_0700 888fcef2d8d54126eb36292a12c58261 146 Gene3D G3DSA:3.30.420.130 1 120 4.7E-34 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_0700 888fcef2d8d54126eb36292a12c58261 146 SUPERFAMILY SSF53146 1 112 5.36E-33 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_0623 42c8f60646ceca6eaf269e351446a042 255 SUPERFAMILY SSF52467 2 243 2.89E-85 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSIB_0623 42c8f60646ceca6eaf269e351446a042 255 Gene3D G3DSA:3.30.1600.10 29 168 1.3E-90 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TSIB_0623 42c8f60646ceca6eaf269e351446a042 255 Gene3D G3DSA:3.40.50.1220 12 241 1.3E-90 T 23-10-2018 TSIB_0623 42c8f60646ceca6eaf269e351446a042 255 Pfam PF02146 Sir2 family 20 198 4.5E-58 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 TSIB_0623 42c8f60646ceca6eaf269e351446a042 255 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 56.593 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TSIB_0505 917cb037849fb05dee283cc05463f8b2 266 Hamap MF_00840 Diadenylate cyclase [dacZ]. 9 266 33.403 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TSIB_0505 917cb037849fb05dee283cc05463f8b2 266 PIRSF PIRSF019073 16 266 5.7E-75 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TSIB_0505 917cb037849fb05dee283cc05463f8b2 266 Gene3D G3DSA:3.40.1700.10 169 265 9.5E-16 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TSIB_0505 917cb037849fb05dee283cc05463f8b2 266 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 257 6.0E-23 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TSIB_0505 917cb037849fb05dee283cc05463f8b2 266 SUPERFAMILY SSF143597 111 261 8.37E-31 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TSIB_0422 66ebc51e01557a51f742e69b47b1e9af 489 SUPERFAMILY SSF56731 218 316 1.57E-10 T 23-10-2018 TSIB_0422 66ebc51e01557a51f742e69b47b1e9af 489 SMART SM00493 222 291 2.4E-12 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0422 66ebc51e01557a51f742e69b47b1e9af 489 Gene3D G3DSA:3.40.1360.10 219 333 3.6E-13 T 23-10-2018 TSIB_0422 66ebc51e01557a51f742e69b47b1e9af 489 Hamap MF_00007 DNA primase DnaG [dnaG]. 58 488 36.253 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 TSIB_0422 66ebc51e01557a51f742e69b47b1e9af 489 Pfam PF13662 Toprim domain 223 306 5.7E-13 T 23-10-2018 IPR006171 TOPRIM domain TSIB_2048 ea2054ee83e9271e778de253193c6186 287 Pfam PF04321 RmlD substrate binding domain 1 283 4.3E-87 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TSIB_2048 ea2054ee83e9271e778de253193c6186 287 Gene3D G3DSA:3.90.25.10 164 277 4.2E-95 T 23-10-2018 TSIB_2048 ea2054ee83e9271e778de253193c6186 287 Gene3D G3DSA:3.40.50.720 3 271 4.2E-95 T 23-10-2018 TSIB_2048 ea2054ee83e9271e778de253193c6186 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 283 7.1E-109 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TSIB_2048 ea2054ee83e9271e778de253193c6186 287 SUPERFAMILY SSF51735 1 283 3.77E-85 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 Pfam PF01814 Hemerythrin HHE cation binding domain 94 233 6.9E-21 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 Gene3D G3DSA:1.20.120.520 87 306 5.3E-61 T 23-10-2018 TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 Pfam PF04282 Family of unknown function (DUF438) 15 80 4.8E-24 T 23-10-2018 IPR007380 Domain of unknown function DUF438 TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 Pfam PF13596 PAS domain 326 429 8.6E-24 T 23-10-2018 TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 Gene3D G3DSA:3.30.450.20 307 442 3.3E-46 T 23-10-2018 TSIB_1739 1f9d6db364e6ed44804e905dd89dbc24 446 SUPERFAMILY SSF55785 324 422 7.21E-8 T 23-10-2018 IPR035965 PAS domain superfamily TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 1.5E-156 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 8.1E-10 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 399 1.1E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 Gene3D G3DSA:3.90.550.10 1 224 2.0E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 Gene3D G3DSA:2.160.10.10 225 409 3.4E-58 T 23-10-2018 TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 SUPERFAMILY SSF51161 243 409 8.14E-38 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 Pfam PF00483 Nucleotidyl transferase 2 232 3.6E-44 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_1312 8f73de039019013a2b3ecf5bc9e825fa 420 SUPERFAMILY SSF53448 2 312 1.2E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 Pfam PF00410 Ribosomal protein S8 5 130 2.6E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 Gene3D G3DSA:3.30.1370.30 1 69 9.0E-33 T 23-10-2018 TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.25 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 SUPERFAMILY SSF56047 3 130 1.7E-39 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 Gene3D G3DSA:3.30.1490.10 70 128 1.2E-28 T 23-10-2018 TSIB_0304 e57395ef065dc4c7d418a93d580dff5f 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SUPERFAMILY SSF50692 2 91 4.85E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SMART SM01072 107 170 3.4E-16 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 555 684 1.6E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 6.2E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:1.10.8.60 686 793 3.0E-32 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:1.10.8.60 403 507 1.3E-18 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:2.40.40.20 1 92 5.7E-37 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SMART SM01073 8 92 1.3E-42 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SUPERFAMILY SSF52540 179 503 1.44E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:3.40.50.300 510 684 5.6E-75 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:3.40.50.300 176 349 2.3E-73 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SUPERFAMILY SSF54585 92 184 1.18E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:3.10.330.10 93 173 1.0E-8 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 ProSitePatterns PS00674 AAA-protein family signature. 655 673 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Gene3D G3DSA:1.10.8.60 350 385 7.0E-6 T 23-10-2018 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SUPERFAMILY SSF52540 513 791 4.15E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 792 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 4.5E-13 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SMART SM00382 215 351 2.9E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 SMART SM00382 551 687 5.7E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0521 af739acc48ce8ae1f2d56be0f01de56f 810 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 8.4E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TSIB_1054 c3c5cb7f228e6259b3572b22b5da1f5f 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 57 7.4E-8 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSIB_1054 c3c5cb7f228e6259b3572b22b5da1f5f 282 Gene3D G3DSA:1.10.3720.10 68 279 2.0E-22 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1054 c3c5cb7f228e6259b3572b22b5da1f5f 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 277 7.4E-27 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1054 c3c5cb7f228e6259b3572b22b5da1f5f 282 SUPERFAMILY SSF161098 75 265 3.4E-26 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0145 b3b7ddb6729c7d2202735e8c0e7923da 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 4.7E-40 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_0145 b3b7ddb6729c7d2202735e8c0e7923da 202 SUPERFAMILY SSF53323 4 199 1.57E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_0145 b3b7ddb6729c7d2202735e8c0e7923da 202 Gene3D G3DSA:3.40.920.10 1 200 1.4E-48 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_0145 b3b7ddb6729c7d2202735e8c0e7923da 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 193 7.7E-86 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 TSIB_0281 ed952f56f73da18a129689b16db8973b 345 SUPERFAMILY SSF103473 2 342 1.19E-67 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_0281 ed952f56f73da18a129689b16db8973b 345 Gene3D G3DSA:1.20.1250.20 173 345 1.6E-29 T 23-10-2018 TSIB_0281 ed952f56f73da18a129689b16db8973b 345 Gene3D G3DSA:1.20.1250.20 1 166 5.2E-36 T 23-10-2018 TSIB_0281 ed952f56f73da18a129689b16db8973b 345 Pfam PF07690 Major Facilitator Superfamily 3 310 2.5E-44 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 58 7.1E-20 T 23-10-2018 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 SUPERFAMILY SSF54862 2 58 3.77E-15 T 23-10-2018 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 Gene3D G3DSA:3.30.70.20 1 59 1.4E-25 T 23-10-2018 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.2E-11 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 PRINTS PR00352 3Fe-4S ferredoxin signature 44 56 3.2E-11 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0129 e4cb0786660f0fce2ffa49fed86b95d3 59 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.2E-11 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0837 b9f21a61376b4392ca74b1371d1034bd 174 Pfam PF01936 NYN domain 32 162 4.1E-20 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TSIB_0837 b9f21a61376b4392ca74b1371d1034bd 174 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 23 164 5.5E-65 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TSIB_0837 b9f21a61376b4392ca74b1371d1034bd 174 Gene3D G3DSA:3.40.50.1010 24 165 4.5E-10 T 23-10-2018 TSIB_0837 b9f21a61376b4392ca74b1371d1034bd 174 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 31 104 2.0E-32 T 23-10-2018 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 SUPERFAMILY SSF88713 1 309 3.02E-71 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 Pfam PF09095 Domain of unknown function (DUF1926) 392 655 2.9E-81 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 319 384 3.0E-31 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 Gene3D G3DSA:3.20.110.20 1 381 1.6E-180 T 23-10-2018 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 Pfam PF03065 Glycosyl hydrolase family 57 7 290 9.5E-66 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 SUPERFAMILY SSF88688 311 384 1.18E-36 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 Gene3D G3DSA:2.70.98.10 386 659 2.9E-98 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 Pfam PF09094 Domain of unknown function (DUF1925) 311 383 6.1E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TSIB_0455 b58b59baa481f69a2dbe8e1dd01fcf21 659 SUPERFAMILY SSF74650 386 658 3.77E-101 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 6 200 2.0E-97 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 11 22 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 Gene3D G3DSA:3.40.50.10490 10 204 2.3E-69 T 23-10-2018 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 114 138 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 SUPERFAMILY SSF52313 6 194 6.41E-61 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 89 106 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 131 142 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 114 131 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 11 29 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 152 166 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 PRINTS PR00395 Ribosomal protein S2 signature 41 50 1.6E-30 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 Pfam PF00318 Ribosomal protein S2 113 177 4.2E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 Pfam PF00318 Ribosomal protein S2 15 105 6.4E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0349 77dbbaf2275c1181f3a4227888ef75c2 204 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 3 201 49.718 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0882 80ff129b8bb587306dff4db5ded48af1 263 SUPERFAMILY SSF55909 7 261 6.07E-61 T 23-10-2018 TSIB_0882 80ff129b8bb587306dff4db5ded48af1 263 Gene3D G3DSA:3.75.10.10 4 257 3.0E-71 T 23-10-2018 TSIB_0882 80ff129b8bb587306dff4db5ded48af1 263 Pfam PF02274 Amidinotransferase 30 259 1.6E-26 T 23-10-2018 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 3.5E-9 T 23-10-2018 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 166 189 3.5E-9 T 23-10-2018 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 140 165 3.5E-9 T 23-10-2018 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 426 444 3.5E-9 T 23-10-2018 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 PIRSF PIRSF004557 6 461 2.2E-100 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 457 20.661 T 23-10-2018 IPR026593 Protein translocase subunit SecY TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 Pfam PF10559 Plug domain of Sec61p 38 71 3.5E-12 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 Pfam PF00344 SecY translocase 72 441 3.3E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 SUPERFAMILY SSF103491 6 448 3.4E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 Gene3D G3DSA:1.10.3370.10 26 461 1.2E-181 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 451 1.5E-93 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0312 37a4fde4da24a88b34af80a0568fe1e9 461 ProSitePatterns PS00756 Protein secY signature 2. 159 176 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 10 119 3.6E-48 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 SUPERFAMILY SSF56276 10 121 2.75E-46 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 Pfam PF02675 S-adenosylmethionine decarboxylase 13 119 1.5E-42 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 Gene3D G3DSA:3.30.360.110 8 68 4.3E-26 T 23-10-2018 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 Gene3D G3DSA:3.30.160.750 69 123 1.0E-21 T 23-10-2018 TSIB_0850 8e9ade7367bc2ca72cec4e82ee049c82 124 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 7 123 33.386 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_1480 94988492b3adb90e3bc762123ac1dbec 129 Pfam PF04472 Cell division protein SepF 51 126 3.0E-15 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TSIB_1480 94988492b3adb90e3bc762123ac1dbec 129 PIRSF PIRSF019313 1 129 3.8E-33 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea TSIB_1480 94988492b3adb90e3bc762123ac1dbec 129 Gene3D G3DSA:3.30.110.150 44 129 1.2E-26 T 23-10-2018 IPR038594 SepF-like superfamily TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 PIRSF PIRSF000778 7 77 5.5E-23 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 25 39 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 SUPERFAMILY SSF63562 21 75 4.58E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 Pfam PF01192 RNA polymerase Rpb6 25 71 5.5E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 22 77 21.33 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0347 920d2078f989c1cf3a10f71dffb50b2f 77 Gene3D G3DSA:3.90.940.50 21 77 3.2E-27 T 23-10-2018 TSIB_1586 515e36836a74dc8c4579474cc1d5d74f 301 SUPERFAMILY SSF56784 73 298 7.25E-33 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_1586 515e36836a74dc8c4579474cc1d5d74f 301 Gene3D G3DSA:3.40.50.1000 161 301 1.7E-30 T 23-10-2018 IPR023214 HAD superfamily TSIB_1586 515e36836a74dc8c4579474cc1d5d74f 301 Pfam PF13419 Haloacid dehalogenase-like hydrolase 79 271 2.8E-15 T 23-10-2018 TSIB_1586 515e36836a74dc8c4579474cc1d5d74f 301 Gene3D G3DSA:1.10.150.400 87 160 1.0E-37 T 23-10-2018 TSIB_1586 515e36836a74dc8c4579474cc1d5d74f 301 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 171 265 2.6E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1872 98775f0a6baa119039307232186f2077 180 Gene3D G3DSA:3.30.1990.20 149 180 1.1E-9 T 23-10-2018 TSIB_1872 98775f0a6baa119039307232186f2077 180 SUPERFAMILY SSF55729 16 173 4.45E-22 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_1872 98775f0a6baa119039307232186f2077 180 Pfam PF00583 Acetyltransferase (GNAT) family 41 164 9.1E-14 T 23-10-2018 IPR000182 GNAT domain TSIB_1872 98775f0a6baa119039307232186f2077 180 Gene3D G3DSA:3.40.630.30 5 148 1.2E-61 T 23-10-2018 TSIB_1071 110b679704142513d8a17f369667dedf 189 Gene3D G3DSA:3.40.50.360 1 145 4.2E-26 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1071 110b679704142513d8a17f369667dedf 189 Pfam PF03358 NADPH-dependent FMN reductase 1 130 1.6E-19 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSIB_1071 110b679704142513d8a17f369667dedf 189 SUPERFAMILY SSF52218 1 166 4.51E-24 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_0569 e52a5aa6f58c47de885ac7fcd8973394 123 Pfam PF01883 Iron-sulfur cluster assembly protein 24 84 6.5E-9 T 23-10-2018 IPR002744 MIP18 family-like TSIB_0569 e52a5aa6f58c47de885ac7fcd8973394 123 Gene3D G3DSA:3.30.300.130 20 102 1.8E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_0569 e52a5aa6f58c47de885ac7fcd8973394 123 SUPERFAMILY SSF117916 24 86 2.03E-11 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_0411 0047f93ed83d5e3aa848c19dd8ee198a 260 SUPERFAMILY SSF52540 2 226 2.45E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0411 0047f93ed83d5e3aa848c19dd8ee198a 260 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0411 0047f93ed83d5e3aa848c19dd8ee198a 260 Gene3D G3DSA:3.40.50.300 1 249 1.9E-62 T 23-10-2018 TSIB_0411 0047f93ed83d5e3aa848c19dd8ee198a 260 SMART SM00382 26 213 2.6E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0411 0047f93ed83d5e3aa848c19dd8ee198a 260 Pfam PF00005 ABC transporter 18 163 2.1E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0577 cc5c274c303f10c6b75f087a2aec76ee 261 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 11 260 1.6E-81 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 TSIB_0577 cc5c274c303f10c6b75f087a2aec76ee 261 Gene3D G3DSA:3.40.50.10900 1 238 2.4E-71 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TSIB_0577 cc5c274c303f10c6b75f087a2aec76ee 261 SUPERFAMILY SSF159659 2 253 2.35E-46 T 23-10-2018 TSIB_0577 cc5c274c303f10c6b75f087a2aec76ee 261 Pfam PF09754 PAC2 family 19 236 7.2E-48 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TSIB_0180 abde47ae9c70b494736c42d37e7a5f02 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 328 9.3E-41 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 Gene3D G3DSA:3.40.50.10630 253 424 4.0E-48 T 23-10-2018 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 Gene3D G3DSA:2.30.130.10 505 571 3.0E-24 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 514 568 6.0E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 441 502 1.1E-6 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 SUPERFAMILY SSF88697 515 569 2.8E-12 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 SUPERFAMILY SSF52141 267 422 4.97E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 SUPERFAMILY SSF88802 248 502 1.31E-16 T 23-10-2018 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 SMART SM00359 505 571 3.2E-5 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 Pfam PF01472 PUA domain 516 569 3.0E-9 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1831 1b9474d9dad57fda66a3e3030203a3ac 571 SUPERFAMILY SSF51713 1 244 1.96E-20 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 Gene3D G3DSA:2.30.170.20 2 67 1.2E-26 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.071 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 SMART SM00746 7 45 8.0E-13 T 23-10-2018 IPR011017 TRASH domain TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 SUPERFAMILY SSF57716 6 56 1.57E-20 T 23-10-2018 TSIB_0421 e448f0c5b29676a8f3cd30e6a47db851 67 Pfam PF01246 Ribosomal protein L24e 3 60 9.6E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Gene3D G3DSA:3.90.1860.10 539 938 3.3E-175 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Gene3D G3DSA:3.90.1860.10 1 158 3.9E-40 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SUPERFAMILY SSF103365 555 938 7.06E-144 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Pfam PF14528 LAGLIDADG-like domain 364 457 1.0E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SUPERFAMILY SSF51294 97 555 1.24E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SUPERFAMILY SSF103365 4 98 2.09E-30 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SMART SM00306 96 195 1.8E-18 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 PRINTS PR00379 Intein signature 365 377 4.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 PRINTS PR00379 Intein signature 409 424 4.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 PRINTS PR00379 Intein signature 244 256 4.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 PRINTS PR00379 Intein signature 550 559 4.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 PRINTS PR00379 Intein signature 162 175 4.8E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 535 556 1.1E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Pfam PF14890 Intein splicing domain 110 555 3.8E-20 T 23-10-2018 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SUPERFAMILY SSF55608 351 472 1.36E-12 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Pfam PF01139 tRNA-splicing ligase RtcB 46 938 2.3E-178 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 98 175 3.3E-11 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 Gene3D G3DSA:3.10.28.10 243 449 1.9E-22 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1552 f64c741614eddae5c1d5ed9d3b02c890 938 SMART SM00305 513 561 1.2E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0219 3ebc9f55f082f06335e4f5de1609bb02 200 SUPERFAMILY SSF50475 3 190 9.81E-32 T 23-10-2018 TSIB_0219 3ebc9f55f082f06335e4f5de1609bb02 200 Pfam PF04289 Protein of unknown function (DUF447) 10 185 3.9E-22 T 23-10-2018 IPR007386 Protein of unknown function DUF447 TSIB_0219 3ebc9f55f082f06335e4f5de1609bb02 200 PIRSF PIRSF018747 2 193 1.0E-46 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 TSIB_0219 3ebc9f55f082f06335e4f5de1609bb02 200 Gene3D G3DSA:2.30.110.10 2 125 3.3E-9 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSIB_1748 04b19ce49547280c68580241eea8db31 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 37 527 9.9E-189 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TSIB_1748 04b19ce49547280c68580241eea8db31 546 Gene3D G3DSA:3.30.260.10 149 407 2.7E-214 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSIB_1748 04b19ce49547280c68580241eea8db31 546 Gene3D G3DSA:3.50.7.10 220 371 2.7E-214 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TSIB_1748 04b19ce49547280c68580241eea8db31 546 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 63 79 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 SUPERFAMILY SSF54849 151 407 4.27E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSIB_1748 04b19ce49547280c68580241eea8db31 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 39 55 1.2E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 61 79 1.2E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 375 397 1.2E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 409 421 1.2E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 91 110 1.2E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 91 99 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 10 526 4.8E-245 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TSIB_1748 04b19ce49547280c68580241eea8db31 546 SUPERFAMILY SSF52029 214 380 6.91E-63 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TSIB_1748 04b19ce49547280c68580241eea8db31 546 Gene3D G3DSA:1.10.560.10 30 524 2.7E-214 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSIB_1748 04b19ce49547280c68580241eea8db31 546 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 42 54 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1748 04b19ce49547280c68580241eea8db31 546 SUPERFAMILY SSF48592 19 526 4.58E-96 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.1E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 SUPERFAMILY SSF53671 4 313 1.7E-115 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.0E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 4.5E-144 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 Gene3D G3DSA:3.40.50.1370 138 297 2.9E-137 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 84.718 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 Gene3D G3DSA:3.40.50.1370 9 307 2.9E-137 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_1585 2b02c34aba03efe3f9084c799bbb770c 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 1.1E-64 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 SMART SM00839 184 415 9.2E-100 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 3.3E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 SUPERFAMILY SSF51735 182 417 4.83E-82 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1110 c68af3db67c5e8259261e076314ad815 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 1.5E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 1.5E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 1.5E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 1.5E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 Gene3D G3DSA:3.40.50.10860 36 181 2.0E-66 T 23-10-2018 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 Gene3D G3DSA:3.40.50.720 182 418 2.7E-96 T 23-10-2018 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 SUPERFAMILY SSF53223 4 184 2.02E-67 T 23-10-2018 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 1.2E-76 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSIB_1110 c68af3db67c5e8259261e076314ad815 419 PIRSF PIRSF000185 1 418 1.7E-173 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 Pfam PF00664 ABC transporter transmembrane region 28 293 3.2E-45 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 SMART SM00382 364 550 1.4E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 SUPERFAMILY SSF52540 328 571 8.88E-83 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 Gene3D G3DSA:3.40.50.300 329 575 1.8E-90 T 23-10-2018 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 SUPERFAMILY SSF90123 9 326 1.03E-72 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 Gene3D G3DSA:1.20.1560.10 2 322 1.8E-81 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSIB_1081 6a927bc838f69c0c571bede4a7325e97 579 Pfam PF00005 ABC transporter 355 503 1.1E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0321 7b2d14a429208cf7405ef4f827122637 319 Gene3D G3DSA:2.60.120.200 57 318 8.0E-102 T 23-10-2018 TSIB_0321 7b2d14a429208cf7405ef4f827122637 319 SUPERFAMILY SSF49899 65 316 7.55E-78 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TSIB_0321 7b2d14a429208cf7405ef4f827122637 319 Pfam PF00722 Glycosyl hydrolases family 16 110 312 2.8E-40 T 23-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 TSIB_1822 98fdcbeec4a64dfd11ef6af42c52511f 241 Pfam PF06745 KaiC 17 238 5.8E-50 T 23-10-2018 IPR014774 KaiC-like domain TSIB_1822 98fdcbeec4a64dfd11ef6af42c52511f 241 SUPERFAMILY SSF52540 15 237 1.22E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1822 98fdcbeec4a64dfd11ef6af42c52511f 241 Gene3D G3DSA:3.40.50.300 13 239 1.5E-55 T 23-10-2018 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 Gene3D G3DSA:3.40.50.1170 1 201 2.2E-67 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 79 89 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 PIRSF PIRSF500176 1 327 6.4E-99 T 23-10-2018 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 Gene3D G3DSA:3.40.50.40 204 331 3.3E-42 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 PIRSF PIRSF001220 1 329 8.2E-96 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 Pfam PF00710 Asparaginase, N-terminal 3 185 2.3E-59 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 SUPERFAMILY SSF53774 1 329 9.16E-97 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 330 1.4E-99 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 SMART SM00870 3 318 6.3E-120 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 1.5E-11 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_1676 fe254369b325c73f10fef66bdc30ea80 331 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.5E-11 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 1.8E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 1.8E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 1.8E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 1.8E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 1.8E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 306 3.2E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 Gene3D G3DSA:3.30.70.3130 1 101 1.1E-34 T 23-10-2018 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 2.0E-88 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 3.0E-18 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 SUPERFAMILY SSF53335 5 309 1.03E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0238 03c9d4e7019b63dfd8d500fcba4a7318 310 Gene3D G3DSA:3.40.50.150 106 310 4.6E-67 T 23-10-2018 TSIB_0753 8d285e0eb6eeec14769d4c9df10f5d39 280 Pfam PF04055 Radical SAM superfamily 23 187 9.5E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0753 8d285e0eb6eeec14769d4c9df10f5d39 280 SUPERFAMILY SSF102114 6 205 9.68E-16 T 23-10-2018 TSIB_0753 8d285e0eb6eeec14769d4c9df10f5d39 280 Gene3D G3DSA:3.80.30.30 51 253 1.5E-14 T 23-10-2018 TSIB_0753 8d285e0eb6eeec14769d4c9df10f5d39 280 SMART SM00729 18 225 1.9E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0159 91d2ad1968b706460339c8d77283a55b 300 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 294 45.087 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 TSIB_0159 91d2ad1968b706460339c8d77283a55b 300 SUPERFAMILY SSF52540 90 286 9.36E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0159 91d2ad1968b706460339c8d77283a55b 300 Gene3D G3DSA:3.40.50.300 91 293 7.9E-11 T 23-10-2018 TSIB_0159 91d2ad1968b706460339c8d77283a55b 300 Pfam PF03477 ATP cone domain 9 86 1.8E-8 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TSIB_0260 4c0093bae5d907ef0abdc04b403d65a5 144 Pfam PF01797 Transposase IS200 like 18 134 8.7E-37 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 TSIB_0260 4c0093bae5d907ef0abdc04b403d65a5 144 SUPERFAMILY SSF143422 8 134 1.12E-40 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 TSIB_0260 4c0093bae5d907ef0abdc04b403d65a5 144 SMART SM01321 15 134 1.2E-39 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 TSIB_0260 4c0093bae5d907ef0abdc04b403d65a5 144 Gene3D G3DSA:3.30.70.1290 7 141 8.7E-42 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 152 32.416 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 ProSitePatterns PS00464 Ribosomal protein L22 signature. 125 149 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 Gene3D G3DSA:3.90.470.10 3 154 1.2E-50 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 6 151 1.1E-64 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 SUPERFAMILY SSF54843 6 151 1.28E-44 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0293 0ef0dbaa30e8d9b068a22ba9fb5a842c 154 Pfam PF00237 Ribosomal protein L22p/L17e 19 149 6.8E-33 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TSIB_1760 f16a8236c30a5c64278e8d2d5dfa8a22 279 SUPERFAMILY SSF103481 38 136 3.4E-14 T 23-10-2018 TSIB_1760 f16a8236c30a5c64278e8d2d5dfa8a22 279 Pfam PF00892 EamA-like transporter family 146 272 4.5E-29 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1760 f16a8236c30a5c64278e8d2d5dfa8a22 279 Pfam PF00892 EamA-like transporter family 3 134 5.5E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1760 f16a8236c30a5c64278e8d2d5dfa8a22 279 Gene3D G3DSA:1.10.3730.20 183 279 6.3E-5 T 23-10-2018 TSIB_1760 f16a8236c30a5c64278e8d2d5dfa8a22 279 SUPERFAMILY SSF103481 182 275 2.09E-17 T 23-10-2018 TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 Pfam PF00252 Ribosomal protein L16p/L10e 14 160 6.5E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 PIRSF PIRSF005590 1 179 3.4E-70 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 Gene3D G3DSA:3.90.1170.10 1 176 1.9E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 37.628 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea TSIB_1576 e49302aa8a734acfc76bf112027c92df 180 SUPERFAMILY SSF54686 4 167 1.01E-55 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_1525 fe510f31107270585e5de05f8e63e35b 223 Gene3D G3DSA:3.40.50.11570 6 217 1.9E-51 T 23-10-2018 TSIB_1525 fe510f31107270585e5de05f8e63e35b 223 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 213 4.3E-66 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_0593 56da7d1705cd27a045c680af91e4eb48 51 Pfam PF01954 Protein of unknown function DUF104 5 41 1.7E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TSIB_0593 56da7d1705cd27a045c680af91e4eb48 51 Gene3D G3DSA:4.10.1150.10 5 51 9.8E-16 T 23-10-2018 IPR024069 AF2212-like domain superfamily TSIB_0593 56da7d1705cd27a045c680af91e4eb48 51 SUPERFAMILY SSF141694 5 44 1.99E-12 T 23-10-2018 TSIB_0523 ac8888676e9ba35c393837a812f24a91 141 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 98 1.0E-34 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TSIB_0523 ac8888676e9ba35c393837a812f24a91 141 Pfam PF01985 CRS1 / YhbY (CRM) domain 8 95 4.0E-13 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TSIB_0523 ac8888676e9ba35c393837a812f24a91 141 Gene3D G3DSA:3.30.110.60 8 115 1.4E-20 T 23-10-2018 IPR035920 YhbY-like superfamily TSIB_0523 ac8888676e9ba35c393837a812f24a91 141 SMART SM01103 8 95 2.4E-24 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TSIB_0523 ac8888676e9ba35c393837a812f24a91 141 SUPERFAMILY SSF75471 8 103 1.7E-17 T 23-10-2018 IPR035920 YhbY-like superfamily TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 ProSitePatterns PS01331 Thymidylate kinase signature. 98 110 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 Gene3D G3DSA:3.40.50.300 1 204 3.8E-66 T 23-10-2018 TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 Hamap MF_00165 Thymidylate kinase [tmk]. 3 204 27.07 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 SUPERFAMILY SSF52540 1 202 5.54E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 Pfam PF02223 Thymidylate kinase 7 196 1.0E-51 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TSIB_0148 5ff60bcec04ce8f4e4020e2f7df4be06 210 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 3.5E-56 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Gene3D G3DSA:3.90.870.50 9 365 4.5E-144 T 23-10-2018 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 SUPERFAMILY SSF55821 178 393 1.19E-43 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 SUPERFAMILY SSF54975 5 91 3.71E-27 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Gene3D G3DSA:3.30.420.350 489 744 3.1E-103 T 23-10-2018 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 PIRSF PIRSF006256 2 766 1.4E-282 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Gene3D G3DSA:3.30.110.120 255 374 4.5E-144 T 23-10-2018 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 SUPERFAMILY SSF53067 607 738 3.24E-7 T 23-10-2018 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 9 756 2.1E-264 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Pfam PF00708 Acylphosphatase 7 90 6.5E-25 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Gene3D G3DSA:3.30.420.360 386 756 3.1E-103 T 23-10-2018 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Pfam PF07503 HypF finger 111 144 4.1E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Pfam PF07503 HypF finger 161 194 2.6E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TSIB_1495 12201eb5f1a54960bfccd6fd8e0bc73a 773 Pfam PF01300 Telomere recombination 211 386 1.3E-45 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 SMART SM00790 1 229 1.0E-62 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 SUPERFAMILY SSF48310 255 652 9.94E-70 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 259 575 4.3E-22 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 SUPERFAMILY SSF56228 3 232 2.75E-42 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 Gene3D G3DSA:1.10.569.10 282 476 9.9E-17 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 Gene3D G3DSA:3.60.9.10 2 232 2.6E-25 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1686 b7cb65abf8e1181e1dfdf2eaa8da168a 654 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 228 2.5E-39 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 Pfam PF00483 Nucleotidyl transferase 3 231 1.1E-51 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 Gene3D G3DSA:2.160.10.10 243 360 7.2E-19 T 23-10-2018 TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 319 354 1.2E-6 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 293 1.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 SUPERFAMILY SSF53448 1 303 2.06E-78 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 SUPERFAMILY SSF51161 199 355 3.19E-24 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_0150 dc2657ac5a5374a5360123c0869e6e04 361 Gene3D G3DSA:3.90.550.10 1 242 1.1E-77 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 111 1.4E-23 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 151 247 3.3E-23 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 PIRSF PIRSF000538 1 501 1.1E-105 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 Gene3D G3DSA:3.30.420.40 1 264 7.0E-73 T 23-10-2018 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 SUPERFAMILY SSF53067 1 262 1.37E-60 T 23-10-2018 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 SUPERFAMILY SSF53067 267 499 9.07E-43 T 23-10-2018 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 Gene3D G3DSA:3.30.420.40 266 500 1.4E-50 T 23-10-2018 TSIB_0768 581b1e5aa2ba23c03635899a23818a3a 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 273 454 5.0E-33 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 Gene3D G3DSA:3.90.1640.30 332 531 4.7E-9 T 23-10-2018 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 Pfam PF00575 S1 RNA binding domain 130 193 6.3E-9 T 23-10-2018 IPR003029 S1 domain GO:0003676 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 Gene3D G3DSA:2.40.50.140 208 305 1.7E-7 T 23-10-2018 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 SUPERFAMILY SSF64182 337 734 3.4E-41 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 Pfam PF01336 OB-fold nucleic acid binding domain 228 295 3.1E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 SMART SM00316 131 196 1.1E-13 T 23-10-2018 IPR022967 RNA-binding domain, S1 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 Gene3D G3DSA:2.40.50.140 128 202 1.9E-13 T 23-10-2018 TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 SUPERFAMILY SSF57938 4 32 8.11E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 SUPERFAMILY SSF50249 121 195 1.01E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1678 235990ec7f5d80ea91d886147d671fc7 740 SUPERFAMILY SSF50249 225 294 3.18E-9 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1639 1b645fdf48f48b5e5abf8da7f8c50306 332 Pfam PF00676 Dehydrogenase E1 component 15 312 5.0E-97 T 23-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSIB_1639 1b645fdf48f48b5e5abf8da7f8c50306 332 Gene3D G3DSA:3.40.50.970 2 328 3.1E-138 T 23-10-2018 TSIB_1639 1b645fdf48f48b5e5abf8da7f8c50306 332 SUPERFAMILY SSF52518 4 323 1.49E-108 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Gene3D G3DSA:3.50.80.10 1 139 4.9E-57 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 24 602 1.7E-172 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Pfam PF03129 Anticodon binding domain 512 601 9.0E-25 T 23-10-2018 IPR004154 Anticodon-binding TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 2.8E-55 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Gene3D G3DSA:3.30.930.10 202 493 6.6E-63 T 23-10-2018 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 287 491 1.6E-18 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 327 350 2.9E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 293 321 2.9E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 427 455 2.9E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 517 2.9E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 483 2.9E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 SUPERFAMILY SSF52954 503 605 8.16E-30 T 23-10-2018 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 SUPERFAMILY SSF55681 206 488 6.7E-57 T 23-10-2018 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 6.0E-52 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Gene3D G3DSA:3.40.50.800 503 607 1.1E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TSIB_0490 2adb76b91be2bdd2f9ad387d1b385907 625 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 601 28.967 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSIB_2005 9e195bf70fd34148395b5f076b746cb8 176 Pfam PF00571 CBS domain 100 150 5.0E-8 T 23-10-2018 IPR000644 CBS domain TSIB_2005 9e195bf70fd34148395b5f076b746cb8 176 Pfam PF00571 CBS domain 18 69 9.9E-5 T 23-10-2018 IPR000644 CBS domain TSIB_2005 9e195bf70fd34148395b5f076b746cb8 176 SUPERFAMILY SSF54631 5 154 5.82E-23 T 23-10-2018 TSIB_2005 9e195bf70fd34148395b5f076b746cb8 176 Gene3D G3DSA:3.10.580.10 74 159 4.2E-10 T 23-10-2018 TSIB_2005 9e195bf70fd34148395b5f076b746cb8 176 Gene3D G3DSA:3.10.580.10 1 73 1.4E-5 T 23-10-2018 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 289 301 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 SUPERFAMILY SSF51412 5 479 2.09E-123 T 23-10-2018 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 Gene3D G3DSA:3.20.20.70 5 481 6.6E-193 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 PIRSF PIRSF000130 3 483 7.7E-192 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 SMART SM01240 13 468 1.9E-257 T 23-10-2018 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 SUPERFAMILY SSF54631 70 202 6.49E-32 T 23-10-2018 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 468 5.6E-148 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 Pfam PF00571 CBS domain 99 143 1.6E-11 T 23-10-2018 IPR000644 CBS domain TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 Pfam PF00571 CBS domain 150 203 5.5E-17 T 23-10-2018 IPR000644 CBS domain TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 481 79.276 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 450 2.9E-186 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 SMART SM00116 100 147 4.9E-11 T 23-10-2018 IPR000644 CBS domain TSIB_0048 235cbcb3b4c3f5edd0bb06bd3d35aa3d 483 SMART SM00116 157 205 3.1E-12 T 23-10-2018 IPR000644 CBS domain TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 Pfam PF02110 Hydroxyethylthiazole kinase family 10 255 3.9E-86 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 5.6E-43 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 258 33.341 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 SUPERFAMILY SSF53613 8 265 9.82E-66 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 PIRSF PIRSF000513 4 266 4.1E-103 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 Gene3D G3DSA:3.40.1190.20 4 268 2.5E-98 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0465 9db13fd317e89a8ece91e6e2b432e44b 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 256 5.5E-99 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 SMART SM01376 70 134 3.8E-18 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 SUPERFAMILY SSF50104 4 78 2.56E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.856 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 Gene3D G3DSA:2.40.50.140 70 135 3.5E-29 T 23-10-2018 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 SUPERFAMILY SSF50249 71 133 4.2E-14 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 4.2E-48 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 5.6E-12 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 PIRSF PIRSF003025 1 138 4.1E-45 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TSIB_0245 7cbdfe690b773231ebec077ebcf0eac8 138 Gene3D G3DSA:2.30.30.30 2 69 1.1E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_2015 bc3e76a811abead934455d5519baddb3 134 SUPERFAMILY SSF81301 2 108 1.59E-13 T 23-10-2018 TSIB_2015 bc3e76a811abead934455d5519baddb3 134 Gene3D G3DSA:3.30.460.10 5 97 1.3E-7 T 23-10-2018 TSIB_0082 89d9037e5eab1f7e0b4160d7149846a8 367 SMART SM00530 13 68 9.1E-10 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0082 89d9037e5eab1f7e0b4160d7149846a8 367 Pfam PF01381 Helix-turn-helix 14 66 2.4E-8 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0082 89d9037e5eab1f7e0b4160d7149846a8 367 Pfam PF06114 IrrE N-terminal-like domain 162 284 1.9E-17 T 23-10-2018 IPR010359 IrrE N-terminal-like domain TSIB_0082 89d9037e5eab1f7e0b4160d7149846a8 367 SUPERFAMILY SSF47413 13 74 8.45E-11 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_0082 89d9037e5eab1f7e0b4160d7149846a8 367 Gene3D G3DSA:1.10.260.40 11 106 4.5E-12 T 23-10-2018 TSIB_0665 0dc6fc885cd1112f895981c3a8481f4a 261 Gene3D G3DSA:3.60.20.10 15 236 1.1E-13 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0665 0dc6fc885cd1112f895981c3a8481f4a 261 Pfam PF13522 Glutamine amidotransferase domain 71 182 3.2E-8 T 23-10-2018 TSIB_0665 0dc6fc885cd1112f895981c3a8481f4a 261 SUPERFAMILY SSF56235 34 225 4.63E-14 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0209 9eb19a5c6c8426e2a2cc187f2b78edd1 210 Gene3D G3DSA:3.60.160.10 1 210 6.7E-77 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily TSIB_0209 9eb19a5c6c8426e2a2cc187f2b78edd1 210 SUPERFAMILY SSF51219 2 209 1.26E-68 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily TSIB_0209 9eb19a5c6c8426e2a2cc187f2b78edd1 210 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 2 206 4.3E-78 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 TSIB_0209 9eb19a5c6c8426e2a2cc187f2b78edd1 210 Pfam PF01987 Mitochondrial biogenesis AIM24 1 192 1.4E-59 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 SUPERFAMILY SSF50249 80 179 2.61E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 8.6E-65 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 Gene3D G3DSA:3.30.1490.120 1 81 3.3E-31 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 SMART SM00316 80 166 1.4E-17 T 23-10-2018 IPR022967 RNA-binding domain, S1 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.2E-18 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 Gene3D G3DSA:2.40.50.140 82 186 2.4E-31 T 23-10-2018 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 SUPERFAMILY SSF88798 1 78 6.15E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TSIB_0026 c88cefa6c5d4c914edb5ee3b6a08d00b 187 Pfam PF00575 S1 RNA binding domain 78 155 2.4E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 TSIB_1618 5cccfa15aaf4989009641e1f77e51733 90 Gene3D G3DSA:3.10.20.30 2 90 2.3E-15 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1618 5cccfa15aaf4989009641e1f77e51733 90 Pfam PF02597 ThiS family 9 90 2.3E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1618 5cccfa15aaf4989009641e1f77e51733 90 SUPERFAMILY SSF54285 4 90 1.18E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_0525 74bec0ecdd31b82ee32b25f94980ce4a 112 Gene3D G3DSA:1.10.8.140 31 112 1.3E-25 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TSIB_0525 74bec0ecdd31b82ee32b25f94980ce4a 112 Hamap MF_00026 DNA-binding protein . 3 112 16.124 T 23-10-2018 IPR022889 DNA-binding protein, archaeal TSIB_0525 74bec0ecdd31b82ee32b25f94980ce4a 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 1.8E-25 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TSIB_0525 74bec0ecdd31b82ee32b25f94980ce4a 112 PIRSF PIRSF015730 1 112 1.5E-33 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TSIB_0525 74bec0ecdd31b82ee32b25f94980ce4a 112 SUPERFAMILY SSF46950 8 111 2.22E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TSIB_1103 610df300060a06523135d7d38d8f7743 416 Pfam PF04409 Protein of unknown function (DUF530) 85 258 1.0E-17 T 23-10-2018 IPR007503 Protein of unknown function DUF530 TSIB_0714 a35bbeb9979a0fc8c8249d254144fdb4 190 Pfam PF01926 50S ribosome-binding GTPase 2 129 3.6E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0714 a35bbeb9979a0fc8c8249d254144fdb4 190 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 182 21.423 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TSIB_0714 a35bbeb9979a0fc8c8249d254144fdb4 190 SUPERFAMILY SSF52540 2 183 4.24E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0714 a35bbeb9979a0fc8c8249d254144fdb4 190 Gene3D G3DSA:3.40.50.300 1 188 1.4E-47 T 23-10-2018 TSIB_0714 a35bbeb9979a0fc8c8249d254144fdb4 190 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 180 3.4E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1446 92eacf4115546370b2a051e5f7acecfa 237 SUPERFAMILY SSF56281 12 233 1.06E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1446 92eacf4115546370b2a051e5f7acecfa 237 SMART SM00849 27 215 4.1E-39 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1446 92eacf4115546370b2a051e5f7acecfa 237 Gene3D G3DSA:3.60.15.10 5 232 1.7E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1446 92eacf4115546370b2a051e5f7acecfa 237 Pfam PF00753 Metallo-beta-lactamase superfamily 28 215 1.1E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 Gene3D G3DSA:3.40.50.620 1 255 2.9E-101 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 379 2.2E-102 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 3.8E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 3.8E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 3.8E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 3.8E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 Pfam PF00579 tRNA synthetases class I (W and Y) 74 347 7.4E-24 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 Gene3D G3DSA:1.10.240.10 256 383 3.0E-43 T 23-10-2018 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 SUPERFAMILY SSF52374 4 368 1.16E-89 T 23-10-2018 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1964 bf904cd320b31fbe2ccf910b138b6f4f 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 45.783 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSIB_1530 845c7e10932a9c0e052e1f9ec1a160c8 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site TSIB_1530 845c7e10932a9c0e052e1f9ec1a160c8 170 SUPERFAMILY SSF56300 1 160 1.52E-37 T 23-10-2018 TSIB_1530 845c7e10932a9c0e052e1f9ec1a160c8 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 1.0E-31 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSIB_1530 845c7e10932a9c0e052e1f9ec1a160c8 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 9.5E-40 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TSIB_1530 845c7e10932a9c0e052e1f9ec1a160c8 170 Gene3D G3DSA:3.60.21.10 1 159 3.9E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 Pfam PF08494 DEAD/H associated 639 827 2.6E-56 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 SMART SM00487 29 254 9.3E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 PIRSF PIRSF037307 3 862 3.1E-290 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 Gene3D G3DSA:3.40.50.300 265 402 3.8E-25 T 23-10-2018 TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 SMART SM00490 297 383 3.3E-15 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 Pfam PF00270 DEAD/DEAH box helicase 34 217 2.5E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 SUPERFAMILY SSF52540 45 391 1.07E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 Pfam PF00271 Helicase conserved C-terminal domain 274 379 3.3E-16 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0165 d36e08773896e15ed4a43412076d9abf 863 Gene3D G3DSA:3.40.50.300 13 232 2.2E-53 T 23-10-2018 TSIB_0915 f96f4ff717ca711b95763ea737d60eb2 62 SUPERFAMILY SSF89957 1 58 2.09E-11 T 23-10-2018 IPR029756 MTH1187/YkoF-like TSIB_0915 f96f4ff717ca711b95763ea737d60eb2 62 Gene3D G3DSA:3.30.70.930 1 59 6.1E-14 T 23-10-2018 IPR029756 MTH1187/YkoF-like TSIB_0915 f96f4ff717ca711b95763ea737d60eb2 62 Pfam PF01910 Thiamine-binding protein 1 55 3.5E-11 T 23-10-2018 IPR002767 Thiamine-binding protein TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 Gene3D G3DSA:3.30.200.20 13 91 2.1E-27 T 23-10-2018 TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 SMART SM00220 1 222 1.5E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 6 216 7.9E-76 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 SUPERFAMILY SSF56112 3 160 1.07E-29 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 Gene3D G3DSA:1.10.510.10 98 218 2.0E-33 T 23-10-2018 TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 Pfam PF01163 RIO1 family 43 150 2.5E-15 T 23-10-2018 TSIB_1544 43be11637616b17e92ed65a9fbedaf2c 224 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 127 139 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 SUPERFAMILY SSF56235 2 214 9.44E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 540 2.1E-162 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 PIRSF PIRSF001589 1 565 1.5E-132 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 Pfam PF00733 Asparagine synthase 239 549 6.7E-74 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 Pfam PF13537 Glutamine amidotransferase domain 42 163 9.0E-47 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 Gene3D G3DSA:3.60.20.10 5 181 1.9E-67 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_2023 31714e336037e621f6b7bc0b8656e143 566 SUPERFAMILY SSF52402 236 560 2.12E-59 T 23-10-2018 TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 Gene3D G3DSA:3.40.1280.10 1 174 7.6E-79 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 174 9.0E-51 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 171 3.5E-50 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 173 43.168 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 SUPERFAMILY SSF75217 1 171 5.23E-69 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TSIB_1085 f131dece9471f32be481c59f07ffeb00 180 PIRSF PIRSF016123 1 176 1.1E-83 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TSIB_1617 3119f40f1c3bca7789c45a0dc7ff2d66 395 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 17 394 2.7E-170 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein TSIB_1617 3119f40f1c3bca7789c45a0dc7ff2d66 395 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 141 194 3.6E-25 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain TSIB_1617 3119f40f1c3bca7789c45a0dc7ff2d66 395 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 377 395 1.7E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 SMART SM00485 1 101 2.8E-50 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 Pfam PF00752 XPG N-terminal domain 12 101 5.6E-23 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 SMART SM00484 140 221 7.2E-37 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 Pfam PF00867 XPG I-region 141 236 2.2E-29 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 Gene3D G3DSA:1.10.150.20 221 281 2.1E-20 T 23-10-2018 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 Gene3D G3DSA:3.40.50.1010 1 220 1.5E-86 T 23-10-2018 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 3.2E-155 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 339 143.618 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 SUPERFAMILY SSF88723 7 236 9.16E-67 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 3.5E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 3.5E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 3.5E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 3.5E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 3.5E-34 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 SMART SM00279 223 257 4.1E-10 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TSIB_0528 f1388fb2bb4b7ebb8b2fb4d0111b9fc3 340 SUPERFAMILY SSF47807 221 339 5.68E-31 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 SUPERFAMILY SSF55811 48 175 1.76E-32 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 Gene3D G3DSA:3.90.79.10 46 175 1.0E-40 T 23-10-2018 TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 ProSitePatterns PS00893 Nudix box signature. 81 102 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 Pfam PF00293 NUDIX domain 52 169 1.4E-22 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 PRINTS PR00502 NUDIX hydrolase family signature 76 90 3.7E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSIB_1438 a6e70c64caffd9a4eba91f3147153e2f 183 PRINTS PR00502 NUDIX hydrolase family signature 90 105 3.7E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSIB_1907 c69e45142aad601bc69f87ce604678f1 175 Gene3D G3DSA:3.30.460.80 2 130 1.0E-22 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1907 c69e45142aad601bc69f87ce604678f1 175 SUPERFAMILY SSF143243 25 162 3.01E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1907 c69e45142aad601bc69f87ce604678f1 175 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 85 126 3.0E-13 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1907 c69e45142aad601bc69f87ce604678f1 175 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 154 5.4E-24 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1607 670b010356df0d58380194c69318bc8e 67 SUPERFAMILY SSF116820 1 60 2.35E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1607 670b010356df0d58380194c69318bc8e 67 Gene3D G3DSA:1.10.60.20 1 61 5.5E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1607 670b010356df0d58380194c69318bc8e 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1607 670b010356df0d58380194c69318bc8e 67 Pfam PF00833 Ribosomal S17 1 64 1.9E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1607 670b010356df0d58380194c69318bc8e 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 21.677 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 Gene3D G3DSA:3.40.50.300 139 345 6.5E-61 T 23-10-2018 TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 SUPERFAMILY SSF52540 3 344 1.27E-97 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 Gene3D G3DSA:3.40.50.720 1 138 7.1E-51 T 23-10-2018 TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 39 134 3.3E-30 T 23-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 143 339 2.1E-65 T 23-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop TSIB_1074 a0e6f0321c2666d8bb3d4b96b7df0141 363 PIRSF PIRSF026760 1 349 7.6E-132 T 23-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 1.9E-30 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SUPERFAMILY SSF142019 112 350 6.93E-96 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Gene3D G3DSA:3.40.30.10 5 97 1.5E-20 T 23-10-2018 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Gene3D G3DSA:3.30.70.20 540 596 7.2E-14 T 23-10-2018 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SUPERFAMILY SSF140490 435 533 1.1E-35 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Gene3D G3DSA:3.40.50.11540 163 341 2.2E-83 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Gene3D G3DSA:3.10.20.600 342 436 9.8E-32 T 23-10-2018 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Pfam PF10531 SLBB domain 353 401 1.6E-8 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Pfam PF00037 4Fe-4S binding domain 540 563 1.5E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Pfam PF00037 4Fe-4S binding domain 572 593 2.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SUPERFAMILY SSF52833 7 98 4.58E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SUPERFAMILY SSF54862 540 597 1.19E-16 T 23-10-2018 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SMART SM00928 439 484 2.5E-23 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 SUPERFAMILY SSF142984 351 434 1.44E-24 T 23-10-2018 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Gene3D G3DSA:1.20.1440.230 437 538 5.7E-33 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1518 126fd99a426e92031d7bbf2d298f0ecd 602 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 158 329 1.5E-50 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 Gene3D G3DSA:3.40.1080.10 291 545 5.1E-91 T 23-10-2018 TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 SMART SM00882 10 258 4.9E-41 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 PIRSF PIRSF000858 5 546 3.5E-189 T 23-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 SUPERFAMILY SSF100950 8 274 3.07E-65 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 Pfam PF01144 Coenzyme A transferase 14 258 1.5E-33 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 SUPERFAMILY SSF100950 292 541 3.51E-59 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_0955 ba3db19f3ae48c8cbf5ff8413d7aa1fe 546 Gene3D G3DSA:3.40.1080.10 1 281 6.4E-83 T 23-10-2018 TSIB_1456 551219e997c123136e765d2764b1cf82 399 SUPERFAMILY SSF56796 21 398 1.44E-92 T 23-10-2018 TSIB_1456 551219e997c123136e765d2764b1cf82 399 Gene3D G3DSA:3.40.50.1970 19 204 5.4E-40 T 23-10-2018 TSIB_1456 551219e997c123136e765d2764b1cf82 399 Pfam PF00465 Iron-containing alcohol dehydrogenase 27 388 8.7E-92 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSIB_1456 551219e997c123136e765d2764b1cf82 399 Gene3D G3DSA:1.20.1090.10 207 399 1.3E-50 T 23-10-2018 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 197 378 2.7E-56 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 Gene3D G3DSA:3.40.50.10300 193 409 5.1E-70 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 SUPERFAMILY SSF52507 22 221 1.96E-45 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 Gene3D G3DSA:3.40.50.1950 21 192 4.5E-46 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 22 404 1.7E-124 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 Pfam PF02441 Flavoprotein 23 192 3.7E-39 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSIB_0486 dcae1fe7b146cada8e6970ce18307a4e 409 SUPERFAMILY SSF102645 183 407 8.24E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSIB_0130 95e272fe201996b6369757008430bbf7 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 52 113 1.4E-4 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSIB_0130 95e272fe201996b6369757008430bbf7 390 Gene3D G3DSA:3.20.20.70 107 297 3.8E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0130 95e272fe201996b6369757008430bbf7 390 SUPERFAMILY SSF54675 2 115 2.06E-30 T 23-10-2018 TSIB_0130 95e272fe201996b6369757008430bbf7 390 SUPERFAMILY SSF51690 112 385 3.79E-75 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSIB_0130 95e272fe201996b6369757008430bbf7 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 6.1E-27 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TSIB_0130 95e272fe201996b6369757008430bbf7 390 PIRSF PIRSF000484 66 387 7.6E-47 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TSIB_0130 95e272fe201996b6369757008430bbf7 390 PIRSF PIRSF000484 8 70 5.0 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TSIB_0130 95e272fe201996b6369757008430bbf7 390 Gene3D G3DSA:3.90.1170.20 1 106 3.5E-44 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TSIB_0130 95e272fe201996b6369757008430bbf7 390 Gene3D G3DSA:3.20.140.10 321 388 3.5E-6 T 23-10-2018 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 SUPERFAMILY SSF100966 9 110 1.44E-29 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 Gene3D G3DSA:3.30.70.3150 41 131 1.4E-33 T 23-10-2018 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 Pfam PF01873 Domain found in IF2B/IF5 24 136 1.1E-37 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 9 143 34.054 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 SMART SM00653 30 137 1.2E-56 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 10 141 1.2E-52 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TSIB_1533 bccc9024eb1af1049d6d853f9c5c2569 143 SUPERFAMILY SSF75689 107 142 5.36E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_0702 4162e2664d6829aac9f0991176820145 273 SMART SM00849 21 242 6.4E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0702 4162e2664d6829aac9f0991176820145 273 Gene3D G3DSA:3.60.15.10 1 271 1.1E-79 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0702 4162e2664d6829aac9f0991176820145 273 SUPERFAMILY SSF56281 3 270 1.83E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0702 4162e2664d6829aac9f0991176820145 273 Pfam PF00753 Metallo-beta-lactamase superfamily 22 148 1.3E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 Gene3D G3DSA:3.90.76.10 52 198 1.5E-139 T 23-10-2018 TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 88 110 - T 23-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 Gene3D G3DSA:3.40.190.10 199 510 1.5E-139 T 23-10-2018 TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 Gene3D G3DSA:3.10.105.10 279 498 1.5E-139 T 23-10-2018 TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 SUPERFAMILY SSF53850 36 521 9.59E-141 T 23-10-2018 TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 PIRSF PIRSF002741 1 521 3.4E-110 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSIB_1052 8e8b064b815c53308a421788f1172aa1 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 443 2.6E-101 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Pfam PF13187 4Fe-4S dicluster domain 579 626 1.9E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 SUPERFAMILY SSF52518 375 565 2.19E-37 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 611 622 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Gene3D G3DSA:3.40.50.970 8 199 9.3E-54 T 23-10-2018 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 195 3.5E-13 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 PIRSF PIRSF006439 12 632 1.3E-216 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Gene3D G3DSA:3.30.70.20 576 628 1.0E-10 T 23-10-2018 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 413 554 4.0E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 SUPERFAMILY SSF52922 246 322 4.49E-8 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 SUPERFAMILY SSF52518 21 231 5.12E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 SUPERFAMILY SSF54862 572 628 3.03E-12 T 23-10-2018 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 22 626 7.6E-215 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TSIB_1785 52404083629bcf7fd3a39ab740e70b39 632 Gene3D G3DSA:3.40.50.970 397 575 2.2E-25 T 23-10-2018 TSIB_1645 039f77747531da30874d976996bb55e7 78 Pfam PF00364 Biotin-requiring enzyme 4 74 2.9E-14 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TSIB_1645 039f77747531da30874d976996bb55e7 78 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSIB_1645 039f77747531da30874d976996bb55e7 78 Gene3D G3DSA:2.40.50.100 1 77 2.1E-18 T 23-10-2018 TSIB_1645 039f77747531da30874d976996bb55e7 78 SUPERFAMILY SSF51230 1 77 7.33E-17 T 23-10-2018 IPR011053 Single hybrid motif TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 Gene3D G3DSA:3.40.630.10 6 336 5.3E-138 T 23-10-2018 TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 SUPERFAMILY SSF101821 68 177 1.18E-30 T 23-10-2018 TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 SUPERFAMILY SSF53187 5 346 3.59E-71 T 23-10-2018 TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 PIRSF PIRSF001123 1 348 7.5E-125 T 23-10-2018 IPR008007 Peptidase M42 TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 3.6E-113 T 23-10-2018 IPR008007 Peptidase M42 TSIB_1215 838795def9231c1d75dc31edaf1b6594 348 Gene3D G3DSA:2.40.30.40 68 161 5.3E-138 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TSIB_1746 3fc4e4ad75255b05c79e3c309940af25 123 Pfam PF13192 Thioredoxin domain 41 115 3.8E-11 T 23-10-2018 IPR012336 Thioredoxin-like fold TSIB_1746 3fc4e4ad75255b05c79e3c309940af25 123 SUPERFAMILY SSF52833 17 121 4.02E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1746 3fc4e4ad75255b05c79e3c309940af25 123 Gene3D G3DSA:3.40.30.10 26 117 2.9E-18 T 23-10-2018 TSIB_1392 05ab838bcfd4e4fffe4e892be48cf9f5 101 Pfam PF05239 PRC-barrel domain 1 81 2.3E-14 T 23-10-2018 IPR027275 PRC-barrel domain TSIB_1392 05ab838bcfd4e4fffe4e892be48cf9f5 101 Gene3D G3DSA:2.30.30.240 4 81 1.5E-5 T 23-10-2018 TSIB_1392 05ab838bcfd4e4fffe4e892be48cf9f5 101 SUPERFAMILY SSF50346 5 79 2.38E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TSIB_1871 4c13c93829d81e4a522fae66199df318 234 SUPERFAMILY SSF47240 56 214 3.07E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1871 4c13c93829d81e4a522fae66199df318 234 Pfam PF02915 Rubrerythrin 67 207 7.7E-12 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1871 4c13c93829d81e4a522fae66199df318 234 Gene3D G3DSA:1.20.1260.10 58 212 1.9E-28 T 23-10-2018 IPR012347 Ferritin-like TSIB_0273 e961cdd90f0d6fb239698b808d559f0e 459 Pfam PF01554 MatE 31 191 7.7E-35 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0273 e961cdd90f0d6fb239698b808d559f0e 459 Pfam PF01554 MatE 256 416 2.6E-29 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0273 e961cdd90f0d6fb239698b808d559f0e 459 TIGRFAM TIGR00797 matE: MATE efflux family protein 31 429 1.7E-80 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0273 e961cdd90f0d6fb239698b808d559f0e 459 PIRSF PIRSF006603 6 459 1.7E-155 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1820 9f912d949074e06940a957dddfdda556 561 Gene3D G3DSA:3.40.630.10 28 406 7.4E-55 T 23-10-2018 TSIB_1820 9f912d949074e06940a957dddfdda556 561 SUPERFAMILY SSF53187 9 419 5.5E-33 T 23-10-2018 TSIB_1820 9f912d949074e06940a957dddfdda556 561 Gene3D G3DSA:3.50.30.30 73 208 7.4E-55 T 23-10-2018 TSIB_1820 9f912d949074e06940a957dddfdda556 561 Pfam PF04389 Peptidase family M28 226 412 1.6E-18 T 23-10-2018 IPR007484 Peptidase M28 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 SMART SM00382 19 177 0.0041 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 SUPERFAMILY SSF52540 2 217 1.22E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 Pfam PF08423 Rad51 2 217 3.2E-39 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 216 2.5E-74 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 PRINTS PR01874 DNA repair protein radA signature 11 39 4.8E-7 T 23-10-2018 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 PRINTS PR01874 DNA repair protein radA signature 189 215 4.8E-7 T 23-10-2018 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 PIRSF PIRSF003336 1 219 2.1E-98 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 Gene3D G3DSA:3.40.50.300 7 219 4.7E-59 T 23-10-2018 TSIB_0108 afc85e75048ce8bd05b5f95b9a4998d0 228 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 216 37.082 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TSIB_0733 ffa7d18e528ed90e3e6d75499e4326be 148 SUPERFAMILY SSF56784 12 109 7.11E-12 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0733 ffa7d18e528ed90e3e6d75499e4326be 148 Gene3D G3DSA:3.40.50.1000 11 137 1.8E-9 T 23-10-2018 IPR023214 HAD superfamily TSIB_1696 de0f39010b3d94eb9670a33572b06c36 110 SUPERFAMILY SSF53146 3 107 5.1E-22 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_1696 de0f39010b3d94eb9670a33572b06c36 110 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 107 1.8E-13 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSIB_1696 de0f39010b3d94eb9670a33572b06c36 110 Gene3D G3DSA:3.30.420.130 2 110 4.7E-20 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 SUPERFAMILY SSF51735 2 151 4.84E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 Gene3D G3DSA:3.40.50.720 18 307 2.2E-73 T 23-10-2018 TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 18 121 4.9E-22 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 246 5.8E-4 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 SUPERFAMILY SSF55347 132 284 3.6E-27 T 23-10-2018 TSIB_1683 263b392b6dac167129f7ffb6ea09ecfc 333 Gene3D G3DSA:3.30.360.10 128 329 2.2E-73 T 23-10-2018 TSIB_0193 349c74c63a88ca3d61bd29c99ff3ec67 402 PIRSF PIRSF005572 19 402 1.0E-50 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSIB_0193 349c74c63a88ca3d61bd29c99ff3ec67 402 Gene3D G3DSA:3.90.1150.10 11 391 3.1E-145 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0193 349c74c63a88ca3d61bd29c99ff3ec67 402 Pfam PF00266 Aminotransferase class-V 22 390 8.1E-137 T 23-10-2018 IPR000192 Aminotransferase class V domain TSIB_0193 349c74c63a88ca3d61bd29c99ff3ec67 402 Gene3D G3DSA:3.40.640.10 33 291 3.1E-145 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0193 349c74c63a88ca3d61bd29c99ff3ec67 402 SUPERFAMILY SSF53383 9 401 5.38E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 79 186 5.3E-14 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 85 184 2.5E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 184 1.2E-28 T 23-10-2018 TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 Gene3D G3DSA:3.40.50.1000 2 206 2.8E-49 T 23-10-2018 IPR023214 HAD superfamily TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 179 4.1E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 SUPERFAMILY SSF56784 1 211 7.75E-47 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0430 906d8e018b7701c5f4bcd7cc8b0f1718 219 Gene3D G3DSA:1.10.150.520 15 86 2.8E-49 T 23-10-2018 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 421 2.2E-80 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 SUPERFAMILY SSF55120 8 420 1.73E-88 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 418 3.7E-139 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 Gene3D G3DSA:3.30.70.3160 44 129 5.1E-113 T 23-10-2018 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 422 28.923 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 PIRSF PIRSF037016 393 422 0.0094 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 PIRSF PIRSF037016 14 398 1.7E-61 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 Gene3D G3DSA:1.10.1510.30 177 262 5.1E-113 T 23-10-2018 TSIB_0438 28dc8bdc33607eb26cf6a828fd83a7c5 422 Gene3D G3DSA:3.30.2350.20 130 417 5.1E-113 T 23-10-2018 TSIB_1862 ce708fd762c11a2da872c3262fd21cde 147 ProSitePatterns PS01318 TsaA-like domain signature. 79 90 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TSIB_1862 ce708fd762c11a2da872c3262fd21cde 147 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 137 1.8E-55 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TSIB_1862 ce708fd762c11a2da872c3262fd21cde 147 Pfam PF01980 Uncharacterised protein family UPF0066 20 131 2.5E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TSIB_1862 ce708fd762c11a2da872c3262fd21cde 147 Gene3D G3DSA:2.40.30.70 4 146 7.7E-49 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily TSIB_1862 ce708fd762c11a2da872c3262fd21cde 147 SUPERFAMILY SSF118196 2 143 5.89E-51 T 23-10-2018 IPR036413 YaeB-like superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 PIRSF PIRSF001587 1 713 3.2E-294 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 SUPERFAMILY SSF55326 19 178 2.88E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Gene3D G3DSA:3.30.1330.10 362 536 3.4E-57 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 429 533 7.9E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 67 172 7.1E-25 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Gene3D G3DSA:3.90.650.10 539 711 6.1E-42 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 SUPERFAMILY SSF56042 184 402 7.63E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 SUPERFAMILY SSF55326 376 534 9.03E-51 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Gene3D G3DSA:3.30.1330.10 27 176 8.0E-125 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 SUPERFAMILY SSF56042 542 701 2.84E-37 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 706 3.4E-301 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 340 1.2E-35 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 547 680 9.8E-23 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Gene3D G3DSA:3.90.650.10 12 341 8.0E-125 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0056 d39de76240b66e3a255bc1ae07f38ae7 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 261.392 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 4.1E-39 T 23-10-2018 IPR000241 Putative RNA methylase domain TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 Gene3D G3DSA:3.40.50.150 190 365 2.4E-55 T 23-10-2018 TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 SUPERFAMILY SSF143437 88 182 1.92E-13 T 23-10-2018 TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 SMART SM00981 89 182 5.2E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 Pfam PF02926 THUMP domain 32 182 1.1E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 SUPERFAMILY SSF53335 179 359 1.29E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1962 8dd8dcb5b8b77e6e1486c0eb7ac78a06 365 Gene3D G3DSA:3.30.2130.30 4 189 1.6E-76 T 23-10-2018 TSIB_0905 247f61b48881f3928506e94ec9bf3867 431 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 419 6.2E-82 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSIB_0905 247f61b48881f3928506e94ec9bf3867 431 PIRSF PIRSF006066 1 431 1.8E-76 T 23-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSIB_0905 247f61b48881f3928506e94ec9bf3867 431 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 424 1.7E-90 T 23-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 SMART SM00491 459 602 1.2E-43 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Pfam PF13307 Helicase C-terminal domain 441 615 1.4E-36 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Pfam PF06777 Helical and beta-bridge domain 238 428 2.3E-68 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 SMART SM00488 1 252 7.8E-66 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 SMART SM00487 6 277 1.9E-4 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 SUPERFAMILY SSF52540 4 226 5.6E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Pfam PF06733 DEAD_2 62 232 5.2E-31 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 2 624 1.9E-144 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Gene3D G3DSA:1.10.30.20 93 169 6.9E-111 T 23-10-2018 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Gene3D G3DSA:3.40.50.300 18 397 6.9E-111 T 23-10-2018 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Gene3D G3DSA:1.10.275.40 228 365 6.9E-111 T 23-10-2018 TSIB_1213 6746fff03c491d780bc5af3fae9b4906 643 Gene3D G3DSA:3.40.50.300 411 628 1.1E-43 T 23-10-2018 TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 Gene3D G3DSA:1.20.58.220 1 110 1.4E-19 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 Pfam PF01895 PhoU domain 11 94 6.8E-9 T 23-10-2018 IPR026022 PhoU domain TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 SUPERFAMILY SSF116726 103 175 4.19E-17 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 Pfam PF02080 TrkA-C domain 118 176 6.0E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 Gene3D G3DSA:3.30.70.1450 111 190 1.3E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_0155 52a8b0c0925ca0d49436e48de18ac558 197 SUPERFAMILY SSF109755 3 98 4.84E-15 T 23-10-2018 TSIB_0819 4e2209fa198f611ad3f2a025cc84fb62 692 Pfam PF01968 Hydantoinase/oxoprolinase 203 497 5.2E-92 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSIB_0819 4e2209fa198f611ad3f2a025cc84fb62 692 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 178 8.6E-46 T 23-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 SUPERFAMILY SSF56349 4 267 3.53E-60 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 1 271 42.689 T 23-10-2018 IPR033686 Tyrosine recombinase XerA TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 Gene3D G3DSA:1.10.150.130 1 87 2.2E-24 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 Pfam PF00589 Phage integrase family 96 259 1.8E-52 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 74 7.3E-8 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSIB_1219 6a0a4b163c374fd70a82ffb0d3669803 278 Gene3D G3DSA:1.10.443.10 88 278 7.8E-79 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSIB_0386 6e8f2fefb62bff917edb1dddb56f0fcd 156 Pfam PF00692 dUTPase 49 147 1.5E-11 T 23-10-2018 IPR029054 dUTPase-like TSIB_0386 6e8f2fefb62bff917edb1dddb56f0fcd 156 SUPERFAMILY SSF51283 1 152 4.32E-37 T 23-10-2018 IPR036157 dUTPase-like superfamily TSIB_0386 6e8f2fefb62bff917edb1dddb56f0fcd 156 Gene3D G3DSA:2.70.40.10 1 155 3.1E-40 T 23-10-2018 IPR036157 dUTPase-like superfamily TSIB_0386 6e8f2fefb62bff917edb1dddb56f0fcd 156 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 26.322 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSIB_0386 6e8f2fefb62bff917edb1dddb56f0fcd 156 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 3.2E-42 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 SUPERFAMILY SSF52518 23 278 9.57E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 SUPERFAMILY SSF52922 286 395 8.99E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 Gene3D G3DSA:3.40.50.920 282 395 1.2E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 3.6E-75 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 Gene3D G3DSA:3.40.50.970 9 211 1.6E-75 T 23-10-2018 TSIB_1471 a09b544c9e468bcfdfdb0ce0c4332571 405 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 6.7E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 SUPERFAMILY SSF52440 2 95 7.63E-26 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 1 351 42.0 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 351 1.1E-130 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 SUPERFAMILY SSF51246 297 367 4.16E-17 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 Gene3D G3DSA:3.30.470.20 173 364 3.7E-80 T 23-10-2018 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 SUPERFAMILY SSF56059 98 291 3.71E-56 T 23-10-2018 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 Gene3D G3DSA:3.30.1490.20 103 172 3.4E-16 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 Pfam PF02222 ATP-grasp domain 107 272 1.7E-51 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TSIB_1869 7e5edbd77c10980fc1616b33f2ccbf9e 372 Gene3D G3DSA:3.40.50.20 1 102 7.3E-38 T 23-10-2018 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 SUPERFAMILY SSF81271 308 385 4.06E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Gene3D G3DSA:3.40.50.300 207 310 3.1E-6 T 23-10-2018 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Pfam PF01926 50S ribosome-binding GTPase 83 185 2.0E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 2.7E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 SUPERFAMILY SSF52540 83 323 2.02E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Gene3D G3DSA:3.10.20.30 311 387 2.5E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 105 123 3.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 149 167 3.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 84 104 3.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 132 147 3.9E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Pfam PF16897 C-terminal region of MMR_HSR1 domain 205 311 1.5E-17 T 23-10-2018 IPR031662 GTP binding protein, second domain TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Gene3D G3DSA:3.40.50.300 70 201 5.9E-33 T 23-10-2018 TSIB_0628 2ae33d9f67ba2fa31e26588c60aea86b 387 Pfam PF02824 TGS domain 314 385 6.7E-22 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSIB_0470 1613d407c355ebe24e3e21d40c416617 253 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 176 2.7E-28 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0470 1613d407c355ebe24e3e21d40c416617 253 SMART SM00852 6 181 4.7E-38 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0470 1613d407c355ebe24e3e21d40c416617 253 SUPERFAMILY SSF53218 3 208 2.49E-40 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0470 1613d407c355ebe24e3e21d40c416617 253 Pfam PF00994 Probable molybdopterin binding domain 6 178 1.4E-34 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0470 1613d407c355ebe24e3e21d40c416617 253 Gene3D G3DSA:3.40.980.10 4 181 2.6E-53 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0161 509a7656689862f3a106c4fddbf0c934 352 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 43 314 5.0E-116 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 TSIB_0161 509a7656689862f3a106c4fddbf0c934 352 Pfam PF13531 Bacterial extracellular solute-binding protein 44 326 9.9E-33 T 23-10-2018 TSIB_0161 509a7656689862f3a106c4fddbf0c934 352 Gene3D G3DSA:3.40.190.10 130 296 6.4E-123 T 23-10-2018 TSIB_0161 509a7656689862f3a106c4fddbf0c934 352 SUPERFAMILY SSF53850 43 333 4.43E-46 T 23-10-2018 TSIB_0161 509a7656689862f3a106c4fddbf0c934 352 Gene3D G3DSA:3.40.190.10 44 345 6.4E-123 T 23-10-2018 TSIB_0848 3690005528ea6b6d32cf259d70889bb5 383 Gene3D G3DSA:1.20.1530.20 11 382 2.6E-42 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_0848 3690005528ea6b6d32cf259d70889bb5 383 Pfam PF00999 Sodium/hydrogen exchanger family 17 374 8.0E-30 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 62 70 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 288 2.5E-26 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 414 2.5E-26 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 140 2.5E-26 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 244 2.5E-26 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 376 2.5E-26 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 SUPERFAMILY SSF54292 19 98 2.16E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 SUPERFAMILY SSF51905 107 431 9.18E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 Gene3D G3DSA:3.10.20.440 6 102 4.4E-35 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 97 1.6E-28 T 23-10-2018 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 120 426 8.7E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 290 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 334 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 142 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 176 186 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 227 235 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 402 420 8.8E-18 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 Gene3D G3DSA:3.50.50.60 270 476 9.3E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0637 9b4c19f10a0a1c50853a7f423cdcf294 477 Gene3D G3DSA:3.50.50.60 113 263 9.1E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0236 5f5ea1cbaa514b83d236a5aec9a2d0bf 96 Pfam PF01883 Iron-sulfur cluster assembly protein 4 44 7.1E-5 T 23-10-2018 IPR002744 MIP18 family-like TSIB_0236 5f5ea1cbaa514b83d236a5aec9a2d0bf 96 Gene3D G3DSA:3.30.300.130 2 91 2.2E-6 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_0236 5f5ea1cbaa514b83d236a5aec9a2d0bf 96 SUPERFAMILY SSF117916 4 67 3.6E-7 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 SUPERFAMILY SSF118215 12 428 5.89E-101 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 378 398 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 158 180 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 316 342 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 59 79 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 245 264 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 351 370 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 2.0E-40 T 23-10-2018 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 Gene3D G3DSA:1.10.3860.10 1 433 9.2E-122 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSIB_1744 ab5565005ad1e84f0c37ee817d25b162 433 Pfam PF00375 Sodium:dicarboxylate symporter family 14 427 1.9E-107 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Gene3D G3DSA:3.40.50.2000 103 202 1.1E-12 T 23-10-2018 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 PIRSF PIRSF000460 1 766 4.8E-275 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Pfam PF00343 Carbohydrate phosphorylase 266 610 1.7E-30 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Pfam PF00343 Carbohydrate phosphorylase 123 174 6.5E-7 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 106 690 3.0E-255 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 SUPERFAMILY SSF53756 14 722 2.24E-200 T 23-10-2018 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Pfam PF11897 Protein of unknown function (DUF3417) 12 119 1.7E-29 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 584 596 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Gene3D G3DSA:3.40.50.2000 404 724 2.2E-46 T 23-10-2018 TSIB_1321 6413f585b3b385d2d82565a7ebc03abe 831 Gene3D G3DSA:3.40.50.2000 262 403 3.9E-8 T 23-10-2018 TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 Pfam PF06745 KaiC 5 237 1.5E-91 T 23-10-2018 IPR014774 KaiC-like domain TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 PRINTS PR01874 DNA repair protein radA signature 14 42 2.8E-9 T 23-10-2018 TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 PRINTS PR01874 DNA repair protein radA signature 56 73 2.8E-9 T 23-10-2018 TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 PRINTS PR01874 DNA repair protein radA signature 135 159 2.8E-9 T 23-10-2018 TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 SUPERFAMILY SSF52540 3 236 2.95E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 4.2E-141 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 Gene3D G3DSA:3.40.50.300 1 247 1.6E-81 T 23-10-2018 TSIB_1804 6b1f04e66a895c6c8ed2800b4d4630a8 247 Hamap MF_01076 UPF0273 protein . 2 243 63.498 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TSIB_1004 d961e06f1229bf761c7fda7fed60d5d6 138 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.105 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSIB_1004 d961e06f1229bf761c7fda7fed60d5d6 138 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 133 2.9E-28 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSIB_1004 d961e06f1229bf761c7fda7fed60d5d6 138 Gene3D G3DSA:2.20.28.10 69 123 1.8E-26 T 23-10-2018 TSIB_1004 d961e06f1229bf761c7fda7fed60d5d6 138 PIRSF PIRSF004761 1 137 8.0E-35 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 Gene3D G3DSA:1.10.8.1030 35 82 3.6E-20 T 23-10-2018 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 Pfam PF00312 Ribosomal protein S15 73 148 6.0E-19 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 SUPERFAMILY SSF47060 66 142 3.53E-24 T 23-10-2018 IPR009068 S15/NS1, RNA-binding TSIB_1270 781467ac002135d548ea1a0b0757f366 151 SMART SM01387 70 149 3.6E-24 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.114 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 Gene3D G3DSA:1.10.287.10 83 151 1.8E-31 T 23-10-2018 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 97 128 7.0E-4 T 23-10-2018 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 8.1E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1270 781467ac002135d548ea1a0b0757f366 151 SMART SM01386 1 60 9.6E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 74 708 3.4E-255 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 Gene3D G3DSA:3.40.50.300 506 713 3.8E-62 T 23-10-2018 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 Gene3D G3DSA:3.40.50.300 70 491 1.2E-95 T 23-10-2018 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 SUPERFAMILY SSF52540 225 701 2.73E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 Pfam PF13087 AAA domain 483 685 4.6E-58 T 23-10-2018 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 Pfam PF13086 AAA domain 229 478 8.6E-57 T 23-10-2018 TSIB_2009 ca7ebb691fb53cbe89c404df14daa7da 716 Gene3D G3DSA:2.40.30.270 88 182 1.2E-95 T 23-10-2018 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 3 236 1.1E-70 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 Gene3D G3DSA:3.30.980.20 95 177 2.4E-71 T 23-10-2018 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 232 4.1E-16 T 23-10-2018 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 SUPERFAMILY SSF56784 1 230 1.82E-39 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 3 223 6.2E-87 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 219 1.8E-16 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TSIB_0250 5c6c5ad08968c0d20c47aa00d67e9f8e 243 Gene3D G3DSA:3.40.50.1000 3 218 2.4E-71 T 23-10-2018 IPR023214 HAD superfamily TSIB_1797 bec75e16e3e501e5c8f9d0de9d539931 661 Gene3D G3DSA:1.20.1460.20 47 290 2.0E-22 T 23-10-2018 TSIB_1797 bec75e16e3e501e5c8f9d0de9d539931 661 Gene3D G3DSA:3.30.70.2750 149 224 2.0E-22 T 23-10-2018 TSIB_1797 bec75e16e3e501e5c8f9d0de9d539931 661 Gene3D G3DSA:3.30.70.2170 7 311 2.0E-22 T 23-10-2018 TSIB_1797 bec75e16e3e501e5c8f9d0de9d539931 661 Pfam PF01496 V-type ATPase 116kDa subunit family 548 649 6.5E-14 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1797 bec75e16e3e501e5c8f9d0de9d539931 661 Pfam PF01496 V-type ATPase 116kDa subunit family 94 435 5.1E-22 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_0288 12e014025f5267210b78a875651d2a09 359 Gene3D G3DSA:2.40.30.10 39 338 6.3E-118 T 23-10-2018 TSIB_0288 12e014025f5267210b78a875651d2a09 359 Gene3D G3DSA:3.30.1430.10 77 203 6.3E-118 T 23-10-2018 TSIB_0288 12e014025f5267210b78a875651d2a09 359 SUPERFAMILY SSF50447 3 359 1.68E-89 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_0288 12e014025f5267210b78a875651d2a09 359 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 359 48.355 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0288 12e014025f5267210b78a875651d2a09 359 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 6 358 1.5E-124 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0288 12e014025f5267210b78a875651d2a09 359 Gene3D G3DSA:4.10.960.10 6 270 6.3E-118 T 23-10-2018 TSIB_0288 12e014025f5267210b78a875651d2a09 359 ProSitePatterns PS00474 Ribosomal protein L3 signature. 208 231 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site TSIB_0288 12e014025f5267210b78a875651d2a09 359 Pfam PF00297 Ribosomal protein L3 4 359 1.1E-89 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1979 25e7a29061e22df87ee24acb4c353043 190 SUPERFAMILY SSF52949 5 187 1.61E-52 T 23-10-2018 TSIB_1979 25e7a29061e22df87ee24acb4c353043 190 Pfam PF01661 Macro domain 30 155 1.4E-35 T 23-10-2018 IPR002589 Macro domain TSIB_1979 25e7a29061e22df87ee24acb4c353043 190 SMART SM00506 13 156 2.0E-55 T 23-10-2018 IPR002589 Macro domain TSIB_1979 25e7a29061e22df87ee24acb4c353043 190 Gene3D G3DSA:3.40.220.10 1 190 9.3E-56 T 23-10-2018 TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 Gene3D G3DSA:3.90.226.10 19 243 1.2E-65 T 23-10-2018 TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 Pfam PF01957 NfeD-like C-terminal, partner-binding 292 439 1.2E-34 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 Gene3D G3DSA:2.40.50.140 375 450 1.2E-24 T 23-10-2018 TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 SUPERFAMILY SSF141322 371 438 3.27E-13 T 23-10-2018 TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 Pfam PF00574 Clp protease 53 189 5.5E-11 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSIB_0676 46a8259265cb0de6ac15aeed294ab769 451 SUPERFAMILY SSF52096 13 189 5.5E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 7.2E-93 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 Pfam PF07650 KH domain 17 86 9.9E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 SMART SM00322 38 104 7.5E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 SUPERFAMILY SSF54814 7 93 7.59E-24 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 SUPERFAMILY SSF54821 86 186 1.31E-25 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 8.9E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.567 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 Gene3D G3DSA:3.30.1140.32 87 207 2.7E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0294 af091fc1c551c49a08340d38b3dc2cd1 207 Gene3D G3DSA:3.30.300.20 1 86 3.3E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0331 f0646b7ff1f180460110398fc6cfba3b 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 3 44 2.5E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSIB_0331 f0646b7ff1f180460110398fc6cfba3b 282 SUPERFAMILY SSF161098 71 260 6.54E-14 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0331 f0646b7ff1f180460110398fc6cfba3b 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 280 3.1E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0331 f0646b7ff1f180460110398fc6cfba3b 282 Gene3D G3DSA:1.10.3720.10 64 280 4.6E-10 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0630 6d047db8f678e2db79e76567a4b19ff3 351 Pfam PF05544 Proline racemase 26 348 2.2E-120 T 23-10-2018 IPR008794 Proline racemase family TSIB_0630 6d047db8f678e2db79e76567a4b19ff3 351 PIRSF PIRSF029792 18 351 2.9E-126 T 23-10-2018 IPR008794 Proline racemase family TSIB_0630 6d047db8f678e2db79e76567a4b19ff3 351 Gene3D G3DSA:3.10.310.10 162 327 4.3E-137 T 23-10-2018 TSIB_0630 6d047db8f678e2db79e76567a4b19ff3 351 SUPERFAMILY SSF54506 20 348 2.02E-112 T 23-10-2018 TSIB_0630 6d047db8f678e2db79e76567a4b19ff3 351 Gene3D G3DSA:3.10.310.10 22 350 4.3E-137 T 23-10-2018 TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 SUPERFAMILY SSF51735 1 147 6.9E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 3.8E-35 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 SUPERFAMILY SSF48179 172 295 5.1E-29 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 Gene3D G3DSA:1.10.1040.10 172 296 1.5E-43 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 295 5.6E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 Gene3D G3DSA:3.40.50.720 1 171 3.1E-57 T 23-10-2018 TSIB_1019 218ebe87da4ef69f538a0ad8f131dea6 300 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 3.4E-34 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSIB_1884 41ebd371a9aed4562b672e679220cfeb 100 Pfam PF02915 Rubrerythrin 24 89 3.3E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1884 41ebd371a9aed4562b672e679220cfeb 100 SUPERFAMILY SSF47240 6 86 1.03E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1884 41ebd371a9aed4562b672e679220cfeb 100 Gene3D G3DSA:1.20.1260.10 4 75 1.7E-10 T 23-10-2018 IPR012347 Ferritin-like TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 Gene3D G3DSA:3.90.1180.10 1 142 4.4E-58 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.755 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 7.7E-64 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 SUPERFAMILY SSF52161 2 142 1.02E-43 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 PIRSF PIRSF002181 1 142 7.0E-44 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TSIB_0344 20548c62aa6367c61df9839809a6ae01 142 Pfam PF00572 Ribosomal protein L13 3 108 1.5E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:3.40.50.300 291 428 8.3E-57 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:3.40.50.300 948 1101 8.7E-36 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:3.10.28.10 613 790 4.3E-26 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SUPERFAMILY SSF51294 432 950 5.89E-37 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 928 950 1.2E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:3.30.450.380 85 290 1.1E-62 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 434 527 7.3E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SUPERFAMILY SSF52540 176 424 1.64E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Pfam PF00437 Type II/IV secretion system protein 196 428 1.1E-51 T 23-10-2018 IPR001482 Type II/IV secretion system protein TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SUPERFAMILY SSF55608 615 681 3.61E-6 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SMART SM00306 425 551 1.6E-17 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SMART SM00305 905 955 1.8E-15 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:2.170.16.10 874 947 2.4E-11 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Pfam PF14890 Intein splicing domain 435 949 1.3E-30 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 PRINTS PR00379 Intein signature 715 727 6.5E-20 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 PRINTS PR00379 Intein signature 617 629 6.5E-20 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 PRINTS PR00379 Intein signature 743 758 6.5E-20 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 PRINTS PR00379 Intein signature 926 943 6.5E-20 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 PRINTS PR00379 Intein signature 514 527 6.5E-20 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Gene3D G3DSA:2.170.16.10 429 568 6.3E-27 T 23-10-2018 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 Pfam PF14528 LAGLIDADG-like domain 714 791 1.6E-15 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SUPERFAMILY SSF55608 701 807 1.13E-22 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1957 d600bfe2168af8e8e57abdf3973d8ff9 1113 SMART SM00382 323 545 1.6E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1892 773461f9cfeb7658716089f7fd103277 182 SUPERFAMILY SSF47240 23 173 1.68E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1892 773461f9cfeb7658716089f7fd103277 182 Gene3D G3DSA:1.20.1260.10 20 169 4.9E-47 T 23-10-2018 IPR012347 Ferritin-like TSIB_1892 773461f9cfeb7658716089f7fd103277 182 Pfam PF02915 Rubrerythrin 30 164 4.9E-26 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 Pfam PF00013 KH domain 37 84 3.2E-10 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 Pfam PF00013 KH domain 140 187 3.0E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 Gene3D G3DSA:3.30.1370.10 33 115 2.5E-35 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 39 211 5.6E-70 T 23-10-2018 IPR019964 KH domain protein, archaea TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 SUPERFAMILY SSF54791 125 202 1.61E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 Gene3D G3DSA:3.30.1370.10 116 218 1.2E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 SMART SM00322 33 103 8.6E-12 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 SMART SM00322 124 191 3.5E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_1106 9ac1155494212e3eee6ec9254df9b327 220 SUPERFAMILY SSF54791 37 113 9.38E-15 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_0790 0863130345a5301587d17baaf8c0c333 430 Gene3D G3DSA:1.20.1730.10 2 428 8.7E-85 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily TSIB_0790 0863130345a5301587d17baaf8c0c333 430 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 357 377 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site TSIB_0790 0863130345a5301587d17baaf8c0c333 430 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 6 375 8.9E-62 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSIB_0790 0863130345a5301587d17baaf8c0c333 430 Pfam PF00474 Sodium:solute symporter family 5 375 1.0E-51 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSIB_1460 cd808caa9a4826ad3a6c1b16400435dc 332 Gene3D G3DSA:1.10.3470.10 2 329 8.5E-98 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TSIB_1460 cd808caa9a4826ad3a6c1b16400435dc 332 Pfam PF01032 FecCD transport family 12 324 3.6E-90 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSIB_1460 cd808caa9a4826ad3a6c1b16400435dc 332 SUPERFAMILY SSF81345 4 324 2.09E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 PIRSF PIRSF002133 19 147 1.6E-35 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 Gene3D G3DSA:2.40.50.140 28 147 1.0E-48 T 23-10-2018 TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 SUPERFAMILY SSF50249 23 147 8.57E-35 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.3E-79 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.411 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea TSIB_0393 22876909d21c6c4b1a0c33d5de6fbbd6 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 6.2E-48 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1662 fe30278095185bb479d905dbbe25f14b 293 Pfam PF00753 Metallo-beta-lactamase superfamily 19 188 5.0E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1662 fe30278095185bb479d905dbbe25f14b 293 SUPERFAMILY SSF56281 7 252 8.12E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1662 fe30278095185bb479d905dbbe25f14b 293 Gene3D G3DSA:3.60.15.10 1 226 9.7E-31 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1662 fe30278095185bb479d905dbbe25f14b 293 SMART SM00849 18 202 3.0E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1412 b41b501bc8c0b6db446b593f01f2e64f 68 SUPERFAMILY SSF46785 3 62 2.4E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1412 b41b501bc8c0b6db446b593f01f2e64f 68 Gene3D G3DSA:1.10.10.10 3 66 6.9E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1412 b41b501bc8c0b6db446b593f01f2e64f 68 Pfam PF12840 Helix-turn-helix domain 6 48 1.6E-7 T 23-10-2018 TSIB_0533 f36fe15ca4502096b9f4814f0b5269c3 203 Gene3D G3DSA:3.40.50.620 1 200 1.2E-67 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0533 f36fe15ca4502096b9f4814f0b5269c3 203 SUPERFAMILY SSF52402 6 153 2.14E-25 T 23-10-2018 TSIB_0533 f36fe15ca4502096b9f4814f0b5269c3 203 Pfam PF00733 Asparagine synthase 8 65 5.0E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 18 337 7.0E-123 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 Pfam PF02769 AIR synthase related protein, C-terminal domain 188 341 2.8E-25 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 Gene3D G3DSA:3.90.650.10 182 347 2.9E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 Pfam PF00586 AIR synthase related protein, N-terminal domain 73 175 1.3E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 Gene3D G3DSA:3.30.1330.10 17 181 2.1E-52 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 18 346 37.786 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 SUPERFAMILY SSF56042 182 342 3.89E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0064 cee21a9f34740ae0af682266f5805cf6 350 SUPERFAMILY SSF55326 17 180 7.92E-40 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 Gene3D G3DSA:3.30.1780.10 4 320 1.7E-115 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 SUPERFAMILY SSF51735 1 325 2.01E-102 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 316 7.3E-97 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 Hamap MF_00935 Alanine dehydrogenase [ala]. 1 324 44.014 T 23-10-2018 IPR028609 Alanine dehydrogenase, archaeal-type GO:0000286|GO:0006522|GO:0051287 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 PIRSF PIRSF001439 1 326 2.7E-96 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSIB_0634 0c0ce1cf74a44bb9506220a50b75a8be 326 Gene3D G3DSA:3.40.50.720 124 298 1.7E-115 T 23-10-2018 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 229 250 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 19 386 50.36 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 Gene3D G3DSA:3.40.640.10 45 295 1.3E-125 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 SUPERFAMILY SSF53383 7 388 2.89E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 70 337 2.4E-33 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 13 385 1.2E-165 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSIB_0460 b633c12ade13e7bbf608a0f0cbc3ed93 389 Gene3D G3DSA:3.90.1150.10 10 379 1.3E-125 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 Gene3D G3DSA:3.40.50.720 2 345 4.6E-125 T 23-10-2018 TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 SUPERFAMILY SSF51735 1 143 2.04E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 SUPERFAMILY SSF55347 118 255 2.16E-34 T 23-10-2018 TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 344 2.6E-26 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 Gene3D G3DSA:3.30.360.10 118 295 4.6E-125 T 23-10-2018 TSIB_0881 d6cb37611f08c4c2d1f1dd7f59e10436 354 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 112 4.2E-15 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 Pfam PF08544 GHMP kinases C terminal 250 329 2.0E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 SUPERFAMILY SSF55060 180 348 9.54E-42 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 TIGRFAM TIGR00131 gal_kin: galactokinase 2 348 1.2E-76 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 ProSitePatterns PS00106 Galactokinase signature. 8 19 - T 23-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 Gene3D G3DSA:3.30.70.890 181 349 1.4E-57 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00959 Mevalonate kinase family signature 297 314 8.5E-40 T 23-10-2018 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00959 Mevalonate kinase family signature 6 30 8.5E-40 T 23-10-2018 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00959 Mevalonate kinase family signature 137 156 8.5E-40 T 23-10-2018 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00959 Mevalonate kinase family signature 94 116 8.5E-40 T 23-10-2018 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 Gene3D G3DSA:3.30.230.10 2 180 9.0E-57 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PIRSF PIRSF000530 1 349 6.7E-100 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00473 Galactokinase signature 8 26 3.7E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00473 Galactokinase signature 87 105 3.7E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00473 Galactokinase signature 67 78 3.7E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 PRINTS PR00473 Galactokinase signature 234 248 3.7E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 SUPERFAMILY SSF54211 1 178 7.06E-50 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 Pfam PF00288 GHMP kinases N terminal domain 92 156 1.6E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_0583 7d17883808fdbcfcfd22f8c381bf59f9 349 Pfam PF10509 Galactokinase galactose-binding signature 4 35 6.2E-14 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSIB_0636 135d9f92836c030978d841d892233318 379 Pfam PF01266 FAD dependent oxidoreductase 4 348 4.1E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSIB_0636 135d9f92836c030978d841d892233318 379 SUPERFAMILY SSF51905 3 370 4.4E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0636 135d9f92836c030978d841d892233318 379 Gene3D G3DSA:3.30.9.10 81 308 4.3E-137 T 23-10-2018 TSIB_0636 135d9f92836c030978d841d892233318 379 Gene3D G3DSA:3.50.50.60 5 353 4.3E-137 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0636 135d9f92836c030978d841d892233318 379 SUPERFAMILY SSF54373 217 309 1.41E-8 T 23-10-2018 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 SMART SM01403 15 109 1.0E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 Gene3D G3DSA:3.30.70.600 5 111 1.2E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 11 110 24.939 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 Pfam PF00338 Ribosomal protein S10p/S20e 15 108 5.6E-28 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 SUPERFAMILY SSF54999 13 110 3.66E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 ProSitePatterns PS00361 Ribosomal protein S10 signature. 37 52 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 12 110 1.0E-49 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 PRINTS PR00971 Ribosomal protein S10 family signature 13 26 1.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 PRINTS PR00971 Ribosomal protein S10 family signature 48 63 1.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1560 2b2cb41987e0250b56af45a8b1e5b92b 112 PRINTS PR00971 Ribosomal protein S10 family signature 70 84 1.8E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0383 d337ef307beb771f2da663016549dbf6 221 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 9 220 36.544 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 TSIB_0383 d337ef307beb771f2da663016549dbf6 221 ProSitePatterns PS01199 Ribosomal protein L1 signature. 119 138 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0383 d337ef307beb771f2da663016549dbf6 221 SUPERFAMILY SSF56808 10 219 1.29E-64 T 23-10-2018 IPR023674 Ribosomal protein L1-like TSIB_0383 d337ef307beb771f2da663016549dbf6 221 PIRSF PIRSF002155 2 221 1.2E-65 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0383 d337ef307beb771f2da663016549dbf6 221 Pfam PF00687 Ribosomal protein L1p/L10e family 26 215 6.3E-47 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TSIB_0383 d337ef307beb771f2da663016549dbf6 221 Gene3D G3DSA:3.30.190.20 18 218 5.9E-75 T 23-10-2018 TSIB_0383 d337ef307beb771f2da663016549dbf6 221 Gene3D G3DSA:3.40.50.790 64 155 5.9E-75 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 Pfam PF07994 Myo-inositol-1-phosphate synthase 41 209 5.4E-13 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 SUPERFAMILY SSF51735 1 377 4.11E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 Gene3D G3DSA:3.30.360.10 214 317 1.0E-130 T 23-10-2018 TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 PIRSF PIRSF015578 1 377 1.5E-97 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 SUPERFAMILY SSF55347 209 314 9.94E-28 T 23-10-2018 TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 Pfam PF01658 Myo-inositol-1-phosphate synthase 210 315 7.2E-19 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TSIB_1788 84fa340c8334501ea445c6d7c51cf3aa 380 Gene3D G3DSA:3.40.50.720 1 352 1.0E-130 T 23-10-2018 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 562 5.7E-29 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Gene3D G3DSA:3.30.70.20 568 640 2.0E-11 T 23-10-2018 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 SUPERFAMILY SSF52518 14 246 6.68E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 638 1.6E-267 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 SUPERFAMILY SSF54862 585 643 1.71E-13 T 23-10-2018 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 SUPERFAMILY SSF52922 248 311 9.64E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 623 634 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 SUPERFAMILY SSF52518 380 600 2.21E-32 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 3.0E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Gene3D G3DSA:3.40.50.970 7 196 3.0E-54 T 23-10-2018 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 PIRSF PIRSF006439 5 645 2.6E-259 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Pfam PF12838 4Fe-4S dicluster domain 591 637 4.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0146 33769406d4fe53ef416a35ae334567fc 646 Gene3D G3DSA:3.40.50.970 389 567 1.6E-21 T 23-10-2018 TSIB_0303 06410598b7e76ecbc3a1274a88dc2e81 58 ProSitePatterns PS00527 Ribosomal protein S14 signature. 25 46 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0303 06410598b7e76ecbc3a1274a88dc2e81 58 Gene3D G3DSA:4.10.830.10 3 58 1.6E-18 T 23-10-2018 TSIB_0303 06410598b7e76ecbc3a1274a88dc2e81 58 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 4 58 16.632 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 TSIB_0303 06410598b7e76ecbc3a1274a88dc2e81 58 Pfam PF00253 Ribosomal protein S14p/S29e 15 57 2.2E-8 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SUPERFAMILY SSF51294 616 757 2.16E-24 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 774 788 1.4E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 319 334 1.4E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 802 815 1.4E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 853 861 1.4E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 826 838 1.4E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR00379 Intein signature 751 760 3.3E-9 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR00379 Intein signature 565 582 3.3E-9 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 PRINTS PR00379 Intein signature 419 432 3.3E-9 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SUPERFAMILY SSF47413 474 523 5.63E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:1.10.10.10 992 1075 5.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SUPERFAMILY SSF51294 335 589 1.19E-38 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:2.40.50.140 100 135 4.1E-7 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:2.40.50.140 177 256 7.3E-27 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF01381 Helix-turn-helix 479 523 2.9E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SUPERFAMILY SSF52540 755 994 7.06E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SMART SM00306 333 456 1.0E-25 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SMART SM00306 614 722 2.0E-13 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:2.170.16.10 338 477 2.0E-33 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 567 589 6.1E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 735 757 7.9E-10 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:2.170.16.10 510 590 1.8E-18 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:3.30.1640.10 1 99 6.6E-37 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF14890 Intein splicing domain 342 588 9.4E-32 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SMART SM00305 547 594 6.5E-14 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SMART SM00305 719 762 6.2E-7 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF14551 MCM N-terminal domain 8 83 4.1E-13 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SUPERFAMILY SSF50249 9 247 2.06E-63 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 SMART SM00350 100 988 3.4E-98 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF17207 MCM OB domain 104 230 3.4E-36 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:3.40.50.300 713 991 6.3E-96 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:3.40.50.300 262 337 1.9E-21 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Gene3D G3DSA:2.20.28.10 136 176 2.3E-27 T 23-10-2018 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 616 701 5.5E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 335 432 2.4E-21 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF00493 MCM2/3/5 family 582 618 4.3E-6 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF00493 MCM2/3/5 family 757 986 4.0E-91 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_1532 6f3014bb2240bc052b90536b0acb7d11 1076 Pfam PF00493 MCM2/3/5 family 265 335 5.6E-20 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSIB_0054 5224243b54246be908137f45ad02ecda 300 Hamap MF_00568 Quinolinate synthase A [nadA]. 1 298 45.609 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSIB_0054 5224243b54246be908137f45ad02ecda 300 Gene3D G3DSA:3.40.50.10800 85 297 2.8E-122 T 23-10-2018 TSIB_0054 5224243b54246be908137f45ad02ecda 300 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 299 9.8E-116 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSIB_0054 5224243b54246be908137f45ad02ecda 300 SUPERFAMILY SSF142754 2 298 8.63E-114 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSIB_0054 5224243b54246be908137f45ad02ecda 300 Pfam PF02445 Quinolinate synthetase A protein 5 297 1.3E-111 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSIB_0054 5224243b54246be908137f45ad02ecda 300 Gene3D G3DSA:3.40.50.10800 170 254 2.8E-122 T 23-10-2018 TSIB_0054 5224243b54246be908137f45ad02ecda 300 Gene3D G3DSA:3.40.50.10800 5 279 2.8E-122 T 23-10-2018 TSIB_0893 dee49acb24f3778ff0afe658c4b7e3da 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 2.6E-83 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_0893 dee49acb24f3778ff0afe658c4b7e3da 321 Gene3D G3DSA:3.40.50.1100 8 309 1.5E-108 T 23-10-2018 TSIB_0893 dee49acb24f3778ff0afe658c4b7e3da 321 SUPERFAMILY SSF53686 7 314 2.62E-93 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_0893 dee49acb24f3778ff0afe658c4b7e3da 321 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 43 56 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSIB_0893 dee49acb24f3778ff0afe658c4b7e3da 321 Gene3D G3DSA:3.40.50.1100 51 147 1.5E-108 T 23-10-2018 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 Gene3D G3DSA:3.50.50.60 6 430 4.4E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 SUPERFAMILY SSF51905 1 451 1.62E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 PRINTS PR00891 Rab GDI/REP protein family signature 21 38 1.7E-7 T 23-10-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 PRINTS PR00891 Rab GDI/REP protein family signature 212 233 1.7E-7 T 23-10-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 PRINTS PR00891 Rab GDI/REP protein family signature 3 21 1.7E-7 T 23-10-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 PRINTS PR00891 Rab GDI/REP protein family signature 121 136 1.7E-7 T 23-10-2018 IPR018203 GDP dissociation inhibitor GO:0005092|GO:0007264 Reactome: R-HSA-8876198 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 Gene3D G3DSA:3.90.660.50 89 398 4.4E-42 T 23-10-2018 TSIB_1970 49d86e2a864f2ed43e700a52757091f9 464 Pfam PF01593 Flavin containing amine oxidoreductase 11 449 2.9E-24 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSIB_1727 89e1e2755440ba31c834180aa369a137 138 Gene3D G3DSA:1.10.10.10 2 135 1.7E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1727 89e1e2755440ba31c834180aa369a137 138 SMART SM00347 25 120 2.3E-17 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1727 89e1e2755440ba31c834180aa369a137 138 SUPERFAMILY SSF46785 6 134 1.61E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1727 89e1e2755440ba31c834180aa369a137 138 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 29 83 1.0E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_1727 89e1e2755440ba31c834180aa369a137 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 2.1E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1727 89e1e2755440ba31c834180aa369a137 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 2.1E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1727 89e1e2755440ba31c834180aa369a137 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 2.1E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_0785 42c926ca7cc37d3687287b0f5616cd66 156 Gene3D G3DSA:1.20.5.340 8 138 1.8E-5 T 23-10-2018 TSIB_0785 42c926ca7cc37d3687287b0f5616cd66 156 Pfam PF05377 Flagella accessory protein C (FlaC) 46 99 7.2E-22 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 155 4.7E-25 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 SUPERFAMILY SSF52540 1 105 7.14E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 Gene3D G3DSA:3.20.20.20 159 225 1.9E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 111 6.2E-19 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 Pfam PF04060 Putative Fe-S cluster 161 191 1.3E-7 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 TSIB_0763 85bd0752050ce240852cbbf03e91aa40 245 Gene3D G3DSA:3.40.50.300 1 158 8.8E-28 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 549 576 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Gene3D G3DSA:3.40.228.10 125 497 9.2E-119 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 SUPERFAMILY SSF53706 3 511 2.88E-131 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Gene3D G3DSA:3.40.50.740 63 442 9.2E-119 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Gene3D G3DSA:2.40.40.20 512 627 8.6E-26 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 42 2.9E-5 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Gene3D G3DSA:3.30.2070.10 399 479 9.2E-119 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Gene3D G3DSA:2.20.25.90 2 52 1.2E-9 T 23-10-2018 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Pfam PF01568 Molydopterin dinucleotide binding domain 535 620 3.2E-19 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 SUPERFAMILY SSF50692 512 627 9.72E-29 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 SMART SM00926 1 47 1.4E-6 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0567 cc2bd0eeb4f7490f1e9e0f3a86b0aa48 627 Pfam PF00384 Molybdopterin oxidoreductase 50 422 6.0E-44 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 Pfam PF13186 Iron-sulfur cluster-binding domain 244 307 5.4E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 Pfam PF04055 Radical SAM superfamily 13 154 2.3E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 SUPERFAMILY SSF102114 7 314 1.96E-50 T 23-10-2018 TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 242 330 2.5E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 Gene3D G3DSA:3.20.20.70 3 346 1.3E-43 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 Pfam PF13394 4Fe-4S single cluster domain 14 94 1.6E-5 T 23-10-2018 TSIB_1564 c8ae2efea02187c7194c5bc174fbdb97 355 PIRSF PIRSF037420 2 347 2.1E-45 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Gene3D G3DSA:2.40.50.140 58 141 2.4E-20 T 23-10-2018 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Gene3D G3DSA:3.30.1370.10 149 241 1.1E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 SMART SM00316 63 137 1.9E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Gene3D G3DSA:2.40.50.100 1 57 1.9E-20 T 23-10-2018 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 39.103 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 2.1E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 SUPERFAMILY SSF50249 59 152 1.53E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1350 9e501538a9b32f367eba05490b82deee 251 Pfam PF15985 KH domain 149 194 2.5E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 SUPERFAMILY SSF110324 3 58 7.59E-14 T 23-10-2018 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 SUPERFAMILY SSF54791 148 227 1.71E-17 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSIB_1350 9e501538a9b32f367eba05490b82deee 251 SMART SM00322 146 210 1.3E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_0841 f81a3cddadddf5930da69cc7ef3f3d9a 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 4.9E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_0841 f81a3cddadddf5930da69cc7ef3f3d9a 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 99 6.5E-30 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SUPERFAMILY SSF52540 52 483 7.71E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Pfam PF02732 ERCC4 domain 564 681 3.9E-28 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Pfam PF00270 DEAD/DEAH box helicase 14 166 5.2E-17 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Gene3D G3DSA:1.10.150.20 699 772 6.6E-22 T 23-10-2018 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Gene3D G3DSA:3.40.50.300 209 481 2.2E-104 T 23-10-2018 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Pfam PF00271 Helicase conserved C-terminal domain 346 463 5.5E-24 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Gene3D G3DSA:3.40.50.10130 558 698 1.1E-50 T 23-10-2018 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SUPERFAMILY SSF52980 559 687 5.09E-35 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SMART SM00891 561 641 5.1E-29 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Pfam PF12826 Helix-hairpin-helix motif 716 765 5.8E-10 T 23-10-2018 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Gene3D G3DSA:1.20.1320.20 212 341 2.2E-104 T 23-10-2018 TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SMART SM00490 375 464 3.0E-22 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SMART SM00487 6 210 7.5E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 SUPERFAMILY SSF47781 699 767 2.3E-14 T 23-10-2018 IPR010994 RuvA domain 2-like TSIB_0686 c6b959c2c4e479ea4cda9df0db40b5f1 772 Gene3D G3DSA:3.40.50.300 1 199 1.4E-70 T 23-10-2018 TSIB_1419 bc2118b4b7a19f959484336753ff37e2 278 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 16 259 1.9E-94 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSIB_1419 bc2118b4b7a19f959484336753ff37e2 278 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 14 278 42.837 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSIB_1419 bc2118b4b7a19f959484336753ff37e2 278 Pfam PF01048 Phosphorylase superfamily 15 258 2.2E-53 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSIB_1419 bc2118b4b7a19f959484336753ff37e2 278 Gene3D G3DSA:3.40.50.1580 12 277 2.4E-98 T 23-10-2018 TSIB_1419 bc2118b4b7a19f959484336753ff37e2 278 SUPERFAMILY SSF53167 13 276 9.3E-94 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 SUPERFAMILY SSF102114 22 259 1.96E-13 T 23-10-2018 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 Pfam PF04055 Radical SAM superfamily 40 182 1.8E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 SMART SM00729 22 252 7.6E-23 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 Gene3D G3DSA:3.20.20.70 39 311 9.9E-7 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 8 324 1.5E-125 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TSIB_1473 6e554194b29d999ecb00aff37e62902f 328 PIRSF PIRSF004954 2 322 3.9E-107 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TSIB_1881 9b9048da07ad1b3686752073893f8be3 432 Pfam PF07282 Putative transposase DNA-binding domain 319 388 2.8E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1881 9b9048da07ad1b3686752073893f8be3 432 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 271 346 8.6E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1881 9b9048da07ad1b3686752073893f8be3 432 Pfam PF01385 Probable transposase 174 299 1.5E-37 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 SUPERFAMILY SSF102522 1 161 4.97E-56 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 250 1.6E-78 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 SUPERFAMILY SSF101852 163 252 7.32E-25 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 PIRSF PIRSF006779 1 254 8.7E-83 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 Gene3D G3DSA:3.40.50.10790 1 160 1.4E-61 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TSIB_1083 45d279e093f93adddeb026a22f96c97d 258 Gene3D G3DSA:2.40.30.90 161 254 2.3E-32 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Gene3D G3DSA:3.40.228.10 135 332 1.8E-167 T 23-10-2018 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 SUPERFAMILY SSF53706 7 560 7.85E-191 T 23-10-2018 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Pfam PF01568 Molydopterin dinucleotide binding domain 558 656 1.9E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Pfam PF00384 Molybdopterin oxidoreductase 58 479 1.4E-89 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Gene3D G3DSA:2.20.25.90 7 54 6.9E-8 T 23-10-2018 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 SMART SM00926 5 55 2.6E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 10 662 2.3E-262 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Gene3D G3DSA:2.40.40.20 545 669 3.0E-32 T 23-10-2018 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 SUPERFAMILY SSF50692 527 664 7.46E-34 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 52 1.5E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0067 0cc9ec6ec43a967c5a95f1687489451b 676 Gene3D G3DSA:3.40.50.740 64 522 1.8E-167 T 23-10-2018 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 324 4.9E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 356 4.5E-92 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Gene3D G3DSA:3.40.50.11060 10 129 8.5E-32 T 23-10-2018 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Hamap MF_00900 GTPase HflX [hflX]. 17 391 40.439 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 3.4E-19 T 23-10-2018 IPR032305 GTP-binding protein, middle domain TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Gene3D G3DSA:3.40.50.300 187 363 8.6E-40 T 23-10-2018 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 2.5E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 2.5E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Pfam PF13167 GTP-binding GTPase N-terminal 18 100 8.9E-21 T 23-10-2018 IPR025121 GTPase HflX, N-terminal TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 PIRSF PIRSF006809 2 421 2.4E-113 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 SUPERFAMILY SSF52540 186 358 1.1E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1024 7fa211e723464695e6fde7f8b50711ec 424 Pfam PF01926 50S ribosome-binding GTPase 188 307 1.0E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.5E-35 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 Gene3D G3DSA:2.40.150.20 1 141 7.9E-50 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 SMART SM01374 20 141 2.9E-57 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 20.065 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 SUPERFAMILY SSF50193 16 141 3.53E-45 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0299 613a5b05d7475d1e9b8123d7fffcf360 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 3.4E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 SUPERFAMILY SSF161070 3 425 3.79E-128 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 Pfam PF00209 Sodium:neurotransmitter symporter family 140 424 5.8E-37 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 Pfam PF00209 Sodium:neurotransmitter symporter family 3 120 1.1E-25 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 84 110 7.3E-15 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 7.3E-15 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 366 385 7.3E-15 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1324 7a6073a23dcaff14f9c2116cafb23385 427 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 7.3E-15 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1759 39e339cece0158cc597df3b13d0b664d 254 SUPERFAMILY SSF52402 3 250 5.51E-78 T 23-10-2018 TSIB_1759 39e339cece0158cc597df3b13d0b664d 254 Gene3D G3DSA:3.40.50.620 6 254 5.7E-92 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1759 39e339cece0158cc597df3b13d0b664d 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 50.997 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TSIB_1759 39e339cece0158cc597df3b13d0b664d 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 6 250 1.9E-85 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TSIB_1759 39e339cece0158cc597df3b13d0b664d 254 Pfam PF02540 NAD synthase 10 249 9.5E-90 T 23-10-2018 IPR022310 NAD/GMP synthase TSIB_0463 99a9cd1f72a3c7c337b29fd4311c54aa 161 PIRSF PIRSF024534 4 161 5.9E-48 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW TSIB_0463 99a9cd1f72a3c7c337b29fd4311c54aa 161 Gene3D G3DSA:1.10.1760.20 2 161 4.3E-16 T 23-10-2018 TSIB_0463 99a9cd1f72a3c7c337b29fd4311c54aa 161 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 10 156 9.1E-43 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW TSIB_0463 99a9cd1f72a3c7c337b29fd4311c54aa 161 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 8 160 4.2E-44 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Pfam PF13393 Histidyl-tRNA synthetase 12 326 2.5E-64 T 23-10-2018 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 SUPERFAMILY SSF55681 7 334 5.97E-87 T 23-10-2018 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 388 24.507 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Gene3D G3DSA:3.30.930.10 2 331 1.0E-109 T 23-10-2018 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 330 1.4E-83 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 PIRSF PIRSF001549 3 437 8.8E-139 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Pfam PF03129 Anticodon binding domain 344 435 3.3E-17 T 23-10-2018 IPR004154 Anticodon-binding TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 8 425 2.2E-126 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 5 435 30.974 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 Gene3D G3DSA:3.40.50.800 342 437 5.7E-25 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TSIB_0079 e02e24b63037757dc3d905597aa762b0 437 SUPERFAMILY SSF52954 344 437 3.62E-21 T 23-10-2018 TSIB_0176 d5499db26eebe9ead3bad07408935652 215 SUPERFAMILY SSF53271 7 159 1.08E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_0176 d5499db26eebe9ead3bad07408935652 215 Pfam PF00156 Phosphoribosyl transferase domain 17 152 1.3E-19 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_0176 d5499db26eebe9ead3bad07408935652 215 Gene3D G3DSA:3.40.50.2020 6 181 1.1E-41 T 23-10-2018 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 7.1E-129 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 9.0E-115 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 SUPERFAMILY SSF100950 12 348 6.0E-113 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 Pfam PF01008 Initiation factor 2 subunit family 55 343 3.8E-82 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 Gene3D G3DSA:1.20.120.420 11 156 4.5E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.639 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_1457 f309e1e39282ad0eed58fe8b1c30cfa5 354 Gene3D G3DSA:3.40.50.10470 157 354 9.8E-61 T 23-10-2018 TSIB_1843 1e21a10bc09f1b976046df1b8f5f5baf 170 Pfam PF11447 Protein of unknown function (DUF3201) 9 156 2.1E-71 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 TSIB_1843 1e21a10bc09f1b976046df1b8f5f5baf 170 Gene3D G3DSA:3.30.930.10 1 168 5.7E-55 T 23-10-2018 TSIB_1843 1e21a10bc09f1b976046df1b8f5f5baf 170 SUPERFAMILY SSF142913 4 167 4.71E-48 T 23-10-2018 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 Gene3D G3DSA:3.30.70.920 62 155 3.0E-28 T 23-10-2018 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 SUPERFAMILY SSF46785 9 70 5.83E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 Pfam PF01037 Lrp/AsnC ligand binding domain 76 146 2.7E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 Gene3D G3DSA:1.10.10.10 9 60 1.5E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 8.0E-18 T 23-10-2018 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 SUPERFAMILY SSF54909 70 155 8.18E-23 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 1.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 1.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 1.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0627 a46328ee6303ab0fd3c53f511a250199 155 SMART SM00344 10 116 1.0E-48 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1363 ebb191165e87e7a60b7da5a388e9b298 133 Pfam PF01201 Ribosomal protein S8e 5 128 2.1E-31 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 TSIB_1363 ebb191165e87e7a60b7da5a388e9b298 133 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 4 130 3.9E-46 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1363 ebb191165e87e7a60b7da5a388e9b298 133 ProSitePatterns PS01193 Ribosomal protein S8e signature. 13 32 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1363 ebb191165e87e7a60b7da5a388e9b298 133 Gene3D G3DSA:2.40.10.310 63 133 4.9E-31 T 23-10-2018 TSIB_1363 ebb191165e87e7a60b7da5a388e9b298 133 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 5 129 31.597 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 SUPERFAMILY SSF53041 57 189 8.24E-26 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 49 7.4E-15 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 Gene3D G3DSA:1.10.1660.10 2 51 8.7E-9 T 23-10-2018 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 Gene3D G3DSA:3.40.50.1390 54 154 6.4E-29 T 23-10-2018 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 Pfam PF12728 Helix-turn-helix domain 3 51 4.1E-13 T 23-10-2018 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 SMART SM00857 57 181 1.3E-28 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 Pfam PF00239 Resolvase, N terminal domain 57 190 2.0E-24 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSIB_1735 850e20e4e5fd4e85421425f3be2a524e 203 SUPERFAMILY SSF46955 2 50 1.69E-7 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 125 236 1.3E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Gene3D G3DSA:3.30.70.1130 176 265 4.9E-31 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 SMART SM00316 13 86 3.2E-23 T 23-10-2018 IPR022967 RNA-binding domain, S1 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 SUPERFAMILY SSF116742 88 177 1.7E-22 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Pfam PF00575 S1 RNA binding domain 12 86 1.7E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 SUPERFAMILY SSF110993 179 263 2.22E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Gene3D G3DSA:2.40.50.140 3 88 5.6E-29 T 23-10-2018 TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 SUPERFAMILY SSF50249 10 90 1.78E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 6 266 33.046 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal TSIB_0575 da6e8f4568af7ac57b1b5dd7d1fa47f2 278 Gene3D G3DSA:1.10.150.190 89 174 1.2E-31 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TSIB_0489 f3af1d24553687c569b61d6e9f171ae8 227 Gene3D G3DSA:3.40.1350.70 1 100 3.1E-29 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily TSIB_0489 f3af1d24553687c569b61d6e9f171ae8 227 SUPERFAMILY SSF159612 2 219 1.31E-111 T 23-10-2018 TSIB_0489 f3af1d24553687c569b61d6e9f171ae8 227 Gene3D G3DSA:3.90.79.30 101 220 6.0E-52 T 23-10-2018 TSIB_0489 f3af1d24553687c569b61d6e9f171ae8 227 Pfam PF15517 TBP-interacting protein N-terminus 3 102 1.4E-44 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 Pfam PF00224 Pyruvate kinase, barrel domain 16 349 2.0E-117 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 Gene3D G3DSA:3.40.1380.20 347 480 1.5E-167 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 SUPERFAMILY SSF52935 334 484 1.7E-31 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 SUPERFAMILY SSF51621 14 350 2.44E-91 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 Gene3D G3DSA:2.40.33.10 84 180 1.5E-167 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 73 89 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 255 279 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 305 323 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 198 212 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 228 254 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 324 340 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 PRINTS PR01050 Pyruvate kinase family signature 280 304 1.6E-59 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 SUPERFAMILY SSF50800 85 178 3.14E-27 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 Pfam PF02887 Pyruvate kinase, alpha/beta domain 373 481 1.7E-21 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 16 484 1.5E-173 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSIB_0471 a069fc15cf65027fda38a929cdc6884e 485 Gene3D G3DSA:3.20.20.60 17 346 1.5E-167 T 23-10-2018 TSIB_1196 59b07eb1eabe86b0ad5b6b9794395097 319 Gene3D G3DSA:1.10.260.40 124 217 8.0E-13 T 23-10-2018 TSIB_1196 59b07eb1eabe86b0ad5b6b9794395097 319 Pfam PF01381 Helix-turn-helix 132 181 3.4E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1196 59b07eb1eabe86b0ad5b6b9794395097 319 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 3 301 29.045 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 TSIB_1196 59b07eb1eabe86b0ad5b6b9794395097 319 SMART SM00530 131 186 1.9E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1196 59b07eb1eabe86b0ad5b6b9794395097 319 SUPERFAMILY SSF47413 127 184 5.12E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Gene3D G3DSA:3.90.105.10 26 178 1.3E-106 T 23-10-2018 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 316 1.3E-31 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Gene3D G3DSA:2.40.340.10 331 399 2.6E-24 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 SMART SM00852 184 320 2.9E-38 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Pfam PF00994 Probable molybdopterin binding domain 184 319 7.1E-25 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_1396 83007233ee23b15926b293a30eae9da8 400 SUPERFAMILY SSF63867 332 398 2.22E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 SUPERFAMILY SSF53218 181 323 4.32E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Gene3D G3DSA:2.170.190.11 49 145 1.3E-106 T 23-10-2018 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Gene3D G3DSA:3.40.980.10 179 319 1.3E-106 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 6.7E-41 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 Pfam PF03454 MoeA C-terminal region (domain IV) 334 398 6.8E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1396 83007233ee23b15926b293a30eae9da8 400 SUPERFAMILY SSF63882 7 179 9.68E-54 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 Pfam PF00483 Nucleotidyl transferase 2 233 8.2E-47 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 4.9E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 288 1.4E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 SUPERFAMILY SSF53448 1 300 4.93E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 Gene3D G3DSA:2.160.10.10 240 369 5.6E-18 T 23-10-2018 TSIB_0504 0e74ab3f82f4b90895955ab6e1384d44 413 Gene3D G3DSA:3.90.550.10 1 239 3.2E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1769 24c089c24fc97e2841e6575e5edcbfac 260 SUPERFAMILY SSF52540 16 256 3.31E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1769 24c089c24fc97e2841e6575e5edcbfac 260 Pfam PF06745 KaiC 25 256 6.5E-27 T 23-10-2018 IPR014774 KaiC-like domain TSIB_1769 24c089c24fc97e2841e6575e5edcbfac 260 Gene3D G3DSA:3.40.50.300 11 259 2.3E-36 T 23-10-2018 TSIB_1334 c96322f63bef239ce30e48ff2dd79305 199 SUPERFAMILY SSF46785 16 76 8.44E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1334 c96322f63bef239ce30e48ff2dd79305 199 Gene3D G3DSA:1.10.10.10 2 80 4.2E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1334 c96322f63bef239ce30e48ff2dd79305 199 Pfam PF14544 Domain of unknown function (DUF4443) 80 189 4.4E-53 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 TSIB_1334 c96322f63bef239ce30e48ff2dd79305 199 SUPERFAMILY SSF55261 80 197 1.77E-37 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSIB_1334 c96322f63bef239ce30e48ff2dd79305 199 Gene3D G3DSA:3.30.1360.30 81 190 5.5E-45 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSIB_0488 d16f0883446994e78aecf3b56f4580be 275 Gene3D G3DSA:3.40.50.10470 96 275 1.0E-61 T 23-10-2018 TSIB_0488 d16f0883446994e78aecf3b56f4580be 275 Gene3D G3DSA:1.20.120.420 1 95 7.0E-35 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_0488 d16f0883446994e78aecf3b56f4580be 275 SUPERFAMILY SSF100950 5 272 1.57E-67 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_0488 d16f0883446994e78aecf3b56f4580be 275 Pfam PF01008 Initiation factor 2 subunit family 32 271 2.0E-51 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 PIRSF PIRSF000164 2 303 1.5E-79 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 SUPERFAMILY SSF51395 3 302 2.96E-78 T 23-10-2018 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 Gene3D G3DSA:3.20.20.70 2 304 1.3E-87 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 Pfam PF01180 Dihydroorotate dehydrogenase 5 286 8.5E-71 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 41 60 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 302 9.6E-98 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 5 301 35.332 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 TSIB_0441 7206ece4fa689dbfd8568289bbe07b6e 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TSIB_0265 7e16ca3b899325da042bdbd1a4147a70 389 Pfam PF04981 NMD3 family 10 278 3.7E-61 T 23-10-2018 IPR007064 Nmd3, N-terminal TSIB_0265 7e16ca3b899325da042bdbd1a4147a70 389 Gene3D G3DSA:2.40.50.140 334 389 3.6E-6 T 23-10-2018 TSIB_0265 7e16ca3b899325da042bdbd1a4147a70 389 SUPERFAMILY SSF50249 337 385 8.57E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0427 364413c88b203937c4a947267a90551d 245 Gene3D G3DSA:3.40.800.10 37 244 4.7E-20 T 23-10-2018 TSIB_0427 364413c88b203937c4a947267a90551d 245 Pfam PF00491 Arginase family 57 228 4.3E-19 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_0427 364413c88b203937c4a947267a90551d 245 SUPERFAMILY SSF52768 59 228 1.12E-23 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TSIB_0427 364413c88b203937c4a947267a90551d 245 PIRSF PIRSF036979 28 242 7.1E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_1865 94c49069c1b60847a1e7d4042f90718e 251 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1865 94c49069c1b60847a1e7d4042f90718e 251 Pfam PF00005 ABC transporter 19 163 4.4E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1865 94c49069c1b60847a1e7d4042f90718e 251 SUPERFAMILY SSF52540 3 220 3.33E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1865 94c49069c1b60847a1e7d4042f90718e 251 Gene3D G3DSA:3.40.50.300 3 242 3.9E-65 T 23-10-2018 TSIB_1865 94c49069c1b60847a1e7d4042f90718e 251 SMART SM00382 28 211 2.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0319 8c081fbe5d214252845555eb654695b2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.1E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0319 8c081fbe5d214252845555eb654695b2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.1E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0319 8c081fbe5d214252845555eb654695b2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.1E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0319 8c081fbe5d214252845555eb654695b2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 7.1E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0319 8c081fbe5d214252845555eb654695b2 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSIB_0319 8c081fbe5d214252845555eb654695b2 234 SUPERFAMILY SSF51735 2 216 1.92E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0319 8c081fbe5d214252845555eb654695b2 234 Pfam PF00106 short chain dehydrogenase 2 185 8.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0319 8c081fbe5d214252845555eb654695b2 234 Gene3D G3DSA:3.40.50.720 1 234 5.4E-69 T 23-10-2018 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 27 110 3.0E-39 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 Pfam PF00935 Ribosomal protein L44 34 110 3.6E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 19 110 25.222 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 ProSitePatterns PS01172 Ribosomal protein L44e signature. 78 89 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 SUPERFAMILY SSF57829 19 110 4.07E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSIB_0573 c4a5f0a102c07cbbd0e50cdc88e8f94d 110 Gene3D G3DSA:3.10.450.80 19 110 4.4E-31 T 23-10-2018 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Gene3D G3DSA:3.40.120.10 1 145 5.2E-49 T 23-10-2018 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 SUPERFAMILY SSF53738 250 352 4.71E-14 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Gene3D G3DSA:3.30.310.50 360 451 6.6E-20 T 23-10-2018 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 1.5E-43 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 441 1.0E-154 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 SUPERFAMILY SSF53738 148 248 2.75E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 356 6.7E-9 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Gene3D G3DSA:3.40.120.10 161 344 2.5E-51 T 23-10-2018 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 1.4E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 1.4E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 1.4E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 1.4E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 368 434 2.5E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 SUPERFAMILY SSF55957 344 447 2.09E-22 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Gene3D G3DSA:3.40.120.10 246 349 2.5E-51 T 23-10-2018 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 SUPERFAMILY SSF53738 2 169 1.33E-42 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1776 b7c8c4a26fa8b22994e4880c74aa8bb0 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 149 245 6.0E-24 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_1916 abbeadc57e2ed38d904fe9bda917582f 82 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 27 79 2.2E-20 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSIB_0275 c34aea45c5a334ca17728377ecd106ec 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 1.4E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_0275 c34aea45c5a334ca17728377ecd106ec 304 Gene3D G3DSA:1.20.58.220 132 233 4.0E-11 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_0275 c34aea45c5a334ca17728377ecd106ec 304 SMART SM00966 8 54 5.7E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_0275 c34aea45c5a334ca17728377ecd106ec 304 Pfam PF01895 PhoU domain 138 230 3.7E-11 T 23-10-2018 IPR026022 PhoU domain TSIB_0275 c34aea45c5a334ca17728377ecd106ec 304 SUPERFAMILY SSF109755 127 301 2.88E-15 T 23-10-2018 TSIB_1369 3ef6c5e2d92d05be337030c9d9d911cf 273 Pfam PF01061 ABC-2 type transporter 18 228 5.5E-13 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSIB_2029 5bc6ecf7fe09a2e66e684bb05f5c797b 145 SUPERFAMILY SSF81593 9 133 3.57E-42 T 23-10-2018 TSIB_2029 5bc6ecf7fe09a2e66e684bb05f5c797b 145 SMART SM00748 15 127 7.1E-42 T 23-10-2018 IPR007842 HEPN domain TSIB_2029 5bc6ecf7fe09a2e66e684bb05f5c797b 145 Pfam PF05168 HEPN domain 11 133 1.8E-32 T 23-10-2018 IPR007842 HEPN domain TSIB_2029 5bc6ecf7fe09a2e66e684bb05f5c797b 145 Gene3D G3DSA:1.20.120.330 4 135 3.9E-35 T 23-10-2018 TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 TIGRFAM TIGR00260 thrC: threonine synthase 61 383 6.2E-64 T 23-10-2018 IPR004450 Threonine synthase-like TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 77 377 5.2E-68 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 SUPERFAMILY SSF53686 7 390 1.44E-92 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 Gene3D G3DSA:3.40.50.1100 113 207 1.6E-108 T 23-10-2018 TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 Gene3D G3DSA:3.40.50.1100 66 383 1.6E-108 T 23-10-2018 TSIB_1652 fca3b069d2eab557a7eee68b40f06f5f 392 PIRSF PIRSF038945 43 391 4.2E-87 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TSIB_0497 e0a5cbb470ce76d1cd7bbb70b9362889 335 Pfam PF01343 Peptidase family S49 150 299 3.8E-39 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSIB_0497 e0a5cbb470ce76d1cd7bbb70b9362889 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 92 296 2.9E-68 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TSIB_0497 e0a5cbb470ce76d1cd7bbb70b9362889 335 Gene3D G3DSA:3.40.1750.20 190 256 8.0E-56 T 23-10-2018 TSIB_0497 e0a5cbb470ce76d1cd7bbb70b9362889 335 Gene3D G3DSA:3.90.226.10 94 292 8.0E-56 T 23-10-2018 TSIB_0497 e0a5cbb470ce76d1cd7bbb70b9362889 335 SUPERFAMILY SSF52096 90 286 8.45E-39 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSIB_1592 4f76742461d3a1873bdff7e96ecc90a8 104 Pfam PF04410 Gar1/Naf1 RNA binding region 3 75 1.4E-9 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 TSIB_1592 4f76742461d3a1873bdff7e96ecc90a8 104 Gene3D G3DSA:2.40.10.230 1 75 8.0E-25 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain TSIB_1592 4f76742461d3a1873bdff7e96ecc90a8 104 SUPERFAMILY SSF50447 1 73 1.06E-15 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1592 4f76742461d3a1873bdff7e96ecc90a8 104 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 1.0E-25 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 Pfam PF06068 TIP49 C-terminus 14 404 1.0E-159 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 SMART SM00382 62 354 4.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 Gene3D G3DSA:2.40.50.360 119 243 8.0E-109 T 23-10-2018 TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 Gene3D G3DSA:1.10.8.60 355 439 1.2E-24 T 23-10-2018 TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 SUPERFAMILY SSF52540 36 422 5.04E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 SUPERFAMILY SSF50249 126 207 8.74E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1591 3aae17dc6e7397284e7b236ff5566fab 441 Gene3D G3DSA:3.40.50.300 17 350 8.0E-109 T 23-10-2018 TSIB_0566 ac18fd906247df7b3276b5e9ee0a7932 189 Gene3D G3DSA:1.20.58.1030 4 116 1.2E-38 T 23-10-2018 TSIB_0566 ac18fd906247df7b3276b5e9ee0a7932 189 Gene3D G3DSA:3.40.5.50 137 189 1.6E-22 T 23-10-2018 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 253 288 2.2E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TSIB_0283 a8ee8da8f74789427c712ed173568085 297 PIRSF PIRSF006816 19 296 2.4E-84 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Pfam PF00970 Oxidoreductase FAD-binding domain 36 116 8.6E-9 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Gene3D G3DSA:3.40.50.80 122 253 2.0E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_0283 a8ee8da8f74789427c712ed173568085 297 SUPERFAMILY SSF52343 113 288 1.44E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Gene3D G3DSA:2.40.30.10 21 117 3.8E-20 T 23-10-2018 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Pfam PF00175 Oxidoreductase NAD-binding domain 130 234 5.5E-14 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 PRINTS PR00410 Phenol hydroxylase reductase family signature 55 67 2.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 PRINTS PR00410 Phenol hydroxylase reductase family signature 221 229 2.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 148 2.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_0283 a8ee8da8f74789427c712ed173568085 297 Gene3D G3DSA:2.10.240.10 254 289 2.2E-7 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TSIB_0283 a8ee8da8f74789427c712ed173568085 297 SUPERFAMILY SSF63380 16 121 1.59E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSIB_1563 ea00c1ea27560331196c972d30796396 391 ProSitePatterns PS00216 Sugar transport proteins signature 1. 59 75 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSIB_1563 ea00c1ea27560331196c972d30796396 391 SUPERFAMILY SSF103473 7 389 5.62E-41 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1563 ea00c1ea27560331196c972d30796396 391 Gene3D G3DSA:1.20.1250.20 5 186 1.0E-19 T 23-10-2018 TSIB_1563 ea00c1ea27560331196c972d30796396 391 Gene3D G3DSA:1.20.1250.20 204 391 1.0E-15 T 23-10-2018 TSIB_1563 ea00c1ea27560331196c972d30796396 391 Pfam PF07690 Major Facilitator Superfamily 10 357 1.4E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 SUPERFAMILY SSF52540 136 386 2.7E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Pfam PF16450 Proteasomal ATPase OB/ID domain 67 124 9.5E-8 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 3 399 46.582 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Gene3D G3DSA:2.40.50.140 25 130 9.6E-25 T 23-10-2018 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 SMART SM00382 174 313 1.9E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Gene3D G3DSA:3.40.50.300 131 311 2.2E-69 T 23-10-2018 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 21 382 2.2E-195 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 178 311 1.4E-42 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 Gene3D G3DSA:1.10.8.60 312 383 8.0E-30 T 23-10-2018 TSIB_0862 46a4e68decdb4105bb32192c7db27646 400 ProSitePatterns PS00674 AAA-protein family signature. 281 299 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 Gene3D G3DSA:3.20.20.110 140 441 1.3E-122 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 145 441 5.8E-97 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 SUPERFAMILY SSF54966 6 139 5.76E-38 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 13 442 52.337 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 Gene3D G3DSA:3.30.70.150 4 139 1.1E-43 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 14 441 4.5E-215 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 15 133 5.6E-45 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_1596 874208fe0c3e88f30fea9f24eb701ec8 447 SUPERFAMILY SSF51649 139 444 1.83E-106 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSIB_0182 ff8d294e736ea0870bea9b823fb684ef 414 Gene3D G3DSA:3.40.50.2300 140 325 8.0E-88 T 23-10-2018 TSIB_0182 ff8d294e736ea0870bea9b823fb684ef 414 SUPERFAMILY SSF53822 50 301 3.92E-7 T 23-10-2018 IPR028082 Periplasmic binding protein-like I TSIB_0182 ff8d294e736ea0870bea9b823fb684ef 414 Gene3D G3DSA:3.40.50.2300 39 314 8.0E-88 T 23-10-2018 TSIB_0182 ff8d294e736ea0870bea9b823fb684ef 414 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 340 4.4E-53 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Gene3D G3DSA:3.40.50.20 1 87 4.7E-31 T 23-10-2018 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 SUPERFAMILY SSF52440 2 99 9.59E-33 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 PIRSF PIRSF004602 1 333 7.2E-136 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Pfam PF06849 Protein of unknown function (DUF1246) 5 119 6.5E-35 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 3 333 49.67 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 SUPERFAMILY SSF56059 103 333 2.41E-80 T 23-10-2018 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Gene3D G3DSA:3.30.1490.20 116 176 8.5E-100 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Gene3D G3DSA:3.30.470.20 89 332 8.5E-100 T 23-10-2018 TSIB_0049 615075454bb257ddbfdaaf08830d15b3 333 Pfam PF06973 Domain of unknown function (DUF1297) 154 333 3.2E-74 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TSIB_0852 b00b5a342b9dc96fd01079b4c78b4916 117 SUPERFAMILY SSF46785 4 99 2.12E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0852 b00b5a342b9dc96fd01079b4c78b4916 117 Gene3D G3DSA:1.10.10.10 2 109 3.3E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0852 b00b5a342b9dc96fd01079b4c78b4916 117 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 14 82 5.8E-10 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_1803 f58e19e125daafda314865863e5e8793 319 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 34 106 3.8E-24 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative TSIB_0401 7f747d64c021a9aa6a89c1d6e8331898 277 SUPERFAMILY SSF53167 17 247 2.75E-75 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSIB_0401 7f747d64c021a9aa6a89c1d6e8331898 277 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 75 90 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSIB_0401 7f747d64c021a9aa6a89c1d6e8331898 277 Gene3D G3DSA:3.40.50.1580 14 268 1.3E-85 T 23-10-2018 TSIB_0401 7f747d64c021a9aa6a89c1d6e8331898 277 Pfam PF01048 Phosphorylase superfamily 30 249 2.1E-46 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSIB_0401 7f747d64c021a9aa6a89c1d6e8331898 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 17 255 4.3E-94 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 18 362 4.8E-147 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 Pfam PF04055 Radical SAM superfamily 24 185 2.6E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 26 37 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 Pfam PF13394 4Fe-4S single cluster domain 26 109 1.8E-8 T 23-10-2018 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 Gene3D G3DSA:3.20.20.70 17 134 6.5E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 Gene3D G3DSA:3.20.20.70 135 340 6.9E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 SUPERFAMILY SSF102114 21 332 2.09E-50 T 23-10-2018 TSIB_1007 c1af8b9c14a952362500fe8acb18fd8a 372 Pfam PF13186 Iron-sulfur cluster-binding domain 249 327 8.7E-17 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Gene3D G3DSA:1.10.1060.10 88 193 6.8E-25 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 SUPERFAMILY SSF51971 194 436 1.88E-74 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 38 55 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Gene3D G3DSA:3.30.70.20 618 701 6.3E-15 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 196 489 1.4E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 SUPERFAMILY SSF54292 9 104 1.88E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 SUPERFAMILY SSF53706 710 959 7.62E-17 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 SUPERFAMILY SSF54862 584 701 7.95E-18 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Gene3D G3DSA:3.50.50.60 323 521 3.0E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Gene3D G3DSA:3.50.50.60 194 319 9.2E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 8 80 1.4E-8 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 PRINTS PR00419 Adrenodoxin reductase family signature 328 342 1.3E-22 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 PRINTS PR00419 Adrenodoxin reductase family signature 262 272 1.3E-22 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 PRINTS PR00419 Adrenodoxin reductase family signature 220 233 1.3E-22 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 PRINTS PR00419 Adrenodoxin reductase family signature 361 374 1.3E-22 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 PRINTS PR00419 Adrenodoxin reductase family signature 197 219 1.3E-22 T 23-10-2018 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 SUPERFAMILY SSF46548 103 206 1.05E-20 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1517 e24ee45aa75fa35e6e1ab20d266be7a7 963 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 105 183 9.4E-19 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TSIB_1469 5f90525925cb26fe8d810c2e070e1d8f 170 SUPERFAMILY SSF53323 2 169 4.05E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1469 5f90525925cb26fe8d810c2e070e1d8f 170 Gene3D G3DSA:3.40.920.10 1 170 3.0E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1469 5f90525925cb26fe8d810c2e070e1d8f 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 9.5E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_2024 ef472164d4ffe97054b84e0808360748 344 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 340 3.6E-106 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TSIB_2024 ef472164d4ffe97054b84e0808360748 344 Gene3D G3DSA:3.40.50.2000 1 336 6.1E-130 T 23-10-2018 TSIB_2024 ef472164d4ffe97054b84e0808360748 344 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 9 339 1.5E-118 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSIB_2024 ef472164d4ffe97054b84e0808360748 344 Gene3D G3DSA:3.40.50.2000 168 326 6.1E-130 T 23-10-2018 TSIB_2024 ef472164d4ffe97054b84e0808360748 344 SUPERFAMILY SSF53756 1 340 5.34E-111 T 23-10-2018 TSIB_1805 a73086022ea37e2347bb20e8ea5ba2bd 166 Pfam PF03657 Uncharacterised protein family (UPF0113) 4 164 4.3E-12 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 TSIB_1805 a73086022ea37e2347bb20e8ea5ba2bd 166 Gene3D G3DSA:3.10.450.220 1 92 3.3E-45 T 23-10-2018 TSIB_1805 a73086022ea37e2347bb20e8ea5ba2bd 166 Gene3D G3DSA:2.30.130.10 93 164 8.5E-20 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1755 68b5672207b849412231522cc9f94605 473 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 284 472 1.4E-27 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1755 68b5672207b849412231522cc9f94605 473 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 12 53 3.1E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSIB_1755 68b5672207b849412231522cc9f94605 473 SUPERFAMILY SSF161098 261 454 8.11E-22 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1755 68b5672207b849412231522cc9f94605 473 Gene3D G3DSA:1.10.3720.10 256 472 6.1E-22 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1853 800884e0677e96f979d97e75e865095a 168 Hamap MF_01117 CDP-archaeol synthase [carS]. 11 168 26.918 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TSIB_1853 800884e0677e96f979d97e75e865095a 168 Pfam PF01864 CDP-archaeol synthase 4 168 3.1E-56 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TSIB_0774 96a9a823c83e451d050f20ecc4672b8b 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSIB_0774 96a9a823c83e451d050f20ecc4672b8b 393 SUPERFAMILY SSF53383 5 389 1.63E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0774 96a9a823c83e451d050f20ecc4672b8b 393 Gene3D G3DSA:3.90.1150.10 32 382 4.7E-148 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0774 96a9a823c83e451d050f20ecc4672b8b 393 Pfam PF00155 Aminotransferase class I and II 32 382 7.8E-74 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_0774 96a9a823c83e451d050f20ecc4672b8b 393 Gene3D G3DSA:3.40.640.10 62 284 4.7E-148 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 Gene3D G3DSA:3.40.50.300 5 338 6.6E-80 T 23-10-2018 TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 SUPERFAMILY SSF52540 25 275 1.59E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 330 9.5E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 SMART SM00382 37 243 5.6E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 Pfam PF00005 ABC transporter 29 193 8.7E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0332 6c40a250dfb7f4f7a0d24c382c3a76c7 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 9.4E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_0793 6b29f403d3bdd2c240dadbef86803488 43 SUPERFAMILY SSF52540 1 34 1.24E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0793 6b29f403d3bdd2c240dadbef86803488 43 Pfam PF13175 AAA ATPase domain 1 34 2.8E-11 T 23-10-2018 TSIB_0793 6b29f403d3bdd2c240dadbef86803488 43 Gene3D G3DSA:3.40.50.300 1 34 2.2E-9 T 23-10-2018 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 Pfam PF01416 tRNA pseudouridine synthase 128 227 4.9E-17 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 221 1.4E-53 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 SUPERFAMILY SSF55120 1 233 1.27E-62 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 226 31.106 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 PIRSF PIRSF001430 1 242 1.4E-72 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 Gene3D G3DSA:3.30.70.580 1 101 1.1E-25 T 23-10-2018 TSIB_0618 f8edceb25d07b27ee986025edbc75f6b 266 Gene3D G3DSA:3.30.70.660 102 225 9.2E-23 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TSIB_1339 14191f645bae04a1f97d536b0786e858 326 Pfam PF02272 DHHA1 domain 238 317 8.0E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSIB_1339 14191f645bae04a1f97d536b0786e858 326 SUPERFAMILY SSF64182 21 316 6.02E-50 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TSIB_1339 14191f645bae04a1f97d536b0786e858 326 Gene3D G3DSA:3.90.1640.10 6 195 1.7E-38 T 23-10-2018 TSIB_1339 14191f645bae04a1f97d536b0786e858 326 Pfam PF01368 DHH family 21 148 6.6E-12 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSIB_1339 14191f645bae04a1f97d536b0786e858 326 Gene3D G3DSA:3.10.310.40 221 319 6.6E-6 T 23-10-2018 TSIB_1218 4056eb42f81327636d47ae4c4ea62bca 286 Gene3D G3DSA:3.40.1360.10 7 125 3.2E-6 T 23-10-2018 TSIB_1218 4056eb42f81327636d47ae4c4ea62bca 286 SMART SM00493 10 89 1.6E-8 T 23-10-2018 IPR006171 TOPRIM domain TSIB_1218 4056eb42f81327636d47ae4c4ea62bca 286 Pfam PF01751 Toprim domain 13 95 1.1E-7 T 23-10-2018 IPR006171 TOPRIM domain TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Gene3D G3DSA:1.10.8.50 235 313 3.1E-9 T 23-10-2018 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 356 553 9.0E-90 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 SUPERFAMILY SSF55874 20 232 1.31E-24 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 10 553 31.128 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Pfam PF09239 Topoisomerase VI B subunit, transducer 357 510 3.1E-55 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 12 534 1.4E-225 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 SUPERFAMILY SSF54211 356 517 3.11E-59 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Gene3D G3DSA:3.30.230.10 356 565 1.0E-68 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 SMART SM00387 33 184 2.8E-8 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 132 3.0E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 PIRSF PIRSF006553 3 565 3.2E-210 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSIB_1105 b2f7f0304ab1a2552c9aa91491a2d390 566 Gene3D G3DSA:3.30.565.10 2 234 5.0E-65 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSIB_1296 214c7546c0295a16038707a6f422a890 189 SUPERFAMILY SSF54862 28 111 1.67E-21 T 23-10-2018 TSIB_1296 214c7546c0295a16038707a6f422a890 189 Pfam PF00037 4Fe-4S binding domain 133 155 2.4E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1296 214c7546c0295a16038707a6f422a890 189 Pfam PF00037 4Fe-4S binding domain 163 185 5.7E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1296 214c7546c0295a16038707a6f422a890 189 Gene3D G3DSA:3.30.70.3270 23 133 2.7E-21 T 23-10-2018 TSIB_1296 214c7546c0295a16038707a6f422a890 189 Gene3D G3DSA:3.30.70.20 134 188 1.5E-13 T 23-10-2018 TSIB_1296 214c7546c0295a16038707a6f422a890 189 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1296 214c7546c0295a16038707a6f422a890 189 SUPERFAMILY SSF54862 129 187 2.62E-20 T 23-10-2018 TSIB_1296 214c7546c0295a16038707a6f422a890 189 Pfam PF12838 4Fe-4S dicluster domain 45 91 3.1E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0240 b7fe826a95dabdeff946d81f18a3349d 226 Gene3D G3DSA:3.40.50.11570 6 218 3.6E-44 T 23-10-2018 TSIB_0240 b7fe826a95dabdeff946d81f18a3349d 226 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 214 1.3E-41 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_1747 de5afe93ca0ec21fbda80638062b6b35 197 Pfam PF02676 Methyltransferase TYW3 11 193 5.7E-49 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_1747 de5afe93ca0ec21fbda80638062b6b35 197 SUPERFAMILY SSF111278 7 192 8.5E-61 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_1747 de5afe93ca0ec21fbda80638062b6b35 197 Gene3D G3DSA:3.30.1960.10 2 197 2.9E-68 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TSIB_1747 de5afe93ca0ec21fbda80638062b6b35 197 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 31.282 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 Gene3D G3DSA:3.40.50.880 296 543 3.2E-108 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 SUPERFAMILY SSF52317 299 541 6.11E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 Pfam PF06418 CTP synthase N-terminus 15 276 4.6E-127 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 TIGRFAM TIGR00337 PyrG: CTP synthase 13 537 5.7E-254 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 Hamap MF_01227 CTP synthase [pyrG]. 14 542 52.596 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 Pfam PF00117 Glutamine amidotransferase class-I 312 537 5.8E-58 T 23-10-2018 IPR017926 Glutamine amidotransferase TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 Gene3D G3DSA:3.40.50.300 7 295 2.7E-140 T 23-10-2018 TSIB_1359 4547cbf691bec920b5af82e11234ec2e 544 SUPERFAMILY SSF52540 15 278 1.29E-120 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1045 88525a256e388a469ed202d5e07a00d5 68 SUPERFAMILY SSF54909 8 67 5.63E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_1045 88525a256e388a469ed202d5e07a00d5 68 Gene3D G3DSA:3.30.70.920 1 67 1.9E-23 T 23-10-2018 TSIB_1045 88525a256e388a469ed202d5e07a00d5 68 Pfam PF01037 Lrp/AsnC ligand binding domain 5 67 5.5E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1217 54018f6976257a406a42309134f13f6e 388 SUPERFAMILY SSF53448 22 292 1.64E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1217 54018f6976257a406a42309134f13f6e 388 Pfam PF13641 Glycosyltransferase like family 2 33 259 3.1E-37 T 23-10-2018 TSIB_1217 54018f6976257a406a42309134f13f6e 388 Gene3D G3DSA:3.90.550.10 19 247 7.3E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1233 8d1b070dfeb82f92dc6638688732b7ef 341 SUPERFAMILY SSF48576 4 340 3.17E-97 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSIB_1233 8d1b070dfeb82f92dc6638688732b7ef 341 Pfam PF00348 Polyprenyl synthetase 32 267 2.0E-71 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TSIB_1233 8d1b070dfeb82f92dc6638688732b7ef 341 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSIB_1233 8d1b070dfeb82f92dc6638688732b7ef 341 Gene3D G3DSA:1.10.600.10 1 341 6.4E-135 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSIB_1233 8d1b070dfeb82f92dc6638688732b7ef 341 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 96 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 Gene3D G3DSA:1.10.1060.10 3 153 1.7E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 SUPERFAMILY SSF51971 377 474 1.41E-11 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 427 449 5.4E-22 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 5.4E-22 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 260 5.4E-22 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 415 5.4E-22 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 5.4E-22 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 SUPERFAMILY SSF51971 157 407 7.06E-70 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 473 1.6E-217 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 139 5.0E-39 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 SUPERFAMILY SSF46548 8 167 2.46E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 458 3.5E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 449 2.8E-15 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 2.8E-15 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 414 2.8E-15 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 2.8E-15 T 23-10-2018 TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 Gene3D G3DSA:3.50.50.60 293 480 3.6E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1465 5a506e8c0bb088042c8a166a6d878edb 480 Gene3D G3DSA:3.50.50.60 154 290 1.5E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Gene3D G3DSA:2.40.50.140 68 157 1.5E-22 T 23-10-2018 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 14 195 28.094 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 SMART SM00316 70 151 1.4E-9 T 23-10-2018 IPR022967 RNA-binding domain, S1 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 SUPERFAMILY SSF50249 67 188 5.3E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Gene3D G3DSA:2.40.50.100 13 63 4.3E-17 T 23-10-2018 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Pfam PF10447 Exosome component EXOSC1/CSL4 68 124 2.8E-6 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Gene3D G3DSA:2.20.70.10 158 191 4.6E-13 T 23-10-2018 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 14 50 7.1E-9 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_0492 7fbc3aaeb38f4d3b56065e393ca7f5a2 199 SUPERFAMILY SSF110324 14 65 6.49E-12 T 23-10-2018 TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 Pfam PF01253 Translation initiation factor SUI1 16 85 1.0E-19 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 Hamap MF_00604 Protein translation factor SUI1 homolog. 3 89 23.84 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 PIRSF PIRSF037511 2 93 9.1E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 SUPERFAMILY SSF55159 13 86 6.67E-23 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 2 92 2.3E-35 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TSIB_0296 e18123399dcbe17428f27b1ede94338c 94 Gene3D G3DSA:3.30.780.10 16 94 1.4E-28 T 23-10-2018 TSIB_0731 8d15e327bfabe8e39fc9168f60e4bd5b 161 Gene3D G3DSA:2.20.28.10 117 155 1.0E-18 T 23-10-2018 TSIB_0731 8d15e327bfabe8e39fc9168f60e4bd5b 161 Pfam PF17146 PIN domain of ribonuclease 2 85 5.0E-19 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 TSIB_0731 8d15e327bfabe8e39fc9168f60e4bd5b 161 SMART SM00670 1 98 0.0013 T 23-10-2018 IPR002716 PIN domain TSIB_0731 8d15e327bfabe8e39fc9168f60e4bd5b 161 Gene3D G3DSA:3.40.50.1010 1 116 3.2E-42 T 23-10-2018 TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 Pfam PF00149 Calcineurin-like phosphoesterase 2 185 2.6E-20 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 SUPERFAMILY SSF56300 257 479 2.24E-28 T 23-10-2018 TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 Gene3D G3DSA:3.60.21.10 257 484 3.8E-13 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 SUPERFAMILY SSF56300 2 234 1.97E-48 T 23-10-2018 TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 281 473 9.7E-8 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSIB_0157 237c549309fb2e8b7380d8852e0b60a2 504 Gene3D G3DSA:3.60.21.10 1 256 5.6E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 Gene3D G3DSA:3.30.56.70 331 390 9.5E-20 T 23-10-2018 TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 34 384 1.0E-116 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 SUPERFAMILY SSF53335 16 383 9.39E-112 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 16 389 43.206 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 18 388 1.5E-99 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TSIB_0515 9d25a7ca888ab151f7a22974c77c91a0 391 Gene3D G3DSA:3.40.50.150 13 330 1.8E-108 T 23-10-2018 TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 Gene3D G3DSA:1.10.8.10 72 111 4.8E-21 T 23-10-2018 TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 1 112 8.0E-39 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 Gene3D G3DSA:2.20.70.30 13 71 9.7E-23 T 23-10-2018 IPR038187 NAC A/B domain superfamily TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 SUPERFAMILY SSF46934 72 112 7.23E-10 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 SMART SM01407 9 68 3.9E-19 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 10 111 21.116 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TSIB_1023 429e5df3af64c89eaa08349d896b9662 113 Pfam PF01849 NAC domain 9 67 5.6E-14 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 PIRSF PIRSF000239 1 215 3.1E-69 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 Hamap MF_00401 Peroxiredoxin. 2 215 51.664 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 Gene3D G3DSA:3.40.30.10 1 144 4.6E-44 T 23-10-2018 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 Gene3D G3DSA:3.30.1020.10 145 216 8.1E-35 T 23-10-2018 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 1.8E-9 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 Pfam PF00578 AhpC/TSA family 4 134 3.6E-31 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1903 bc4b47c526a5ab563f49202acc15db48 216 SUPERFAMILY SSF52833 1 215 4.82E-62 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1123 14c32b9febb431bf92b117d9ce42dd3d 365 SUPERFAMILY SSF102114 29 210 5.76E-22 T 23-10-2018 TSIB_1123 14c32b9febb431bf92b117d9ce42dd3d 365 Gene3D G3DSA:3.20.20.70 28 319 1.5E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1123 14c32b9febb431bf92b117d9ce42dd3d 365 Pfam PF04055 Radical SAM superfamily 37 157 5.4E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1123 14c32b9febb431bf92b117d9ce42dd3d 365 Pfam PF13394 4Fe-4S single cluster domain 35 125 2.1E-6 T 23-10-2018 TSIB_0738 5a403d274419360640e126e7a058e9e6 138 SUPERFAMILY SSF55021 53 133 1.65E-28 T 23-10-2018 TSIB_0738 5a403d274419360640e126e7a058e9e6 138 Gene3D G3DSA:3.30.70.1150 51 138 6.3E-37 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TSIB_0738 5a403d274419360640e126e7a058e9e6 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 3.5E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal TSIB_0738 5a403d274419360640e126e7a058e9e6 138 SUPERFAMILY SSF47598 2 49 3.41E-14 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSIB_0738 5a403d274419360640e126e7a058e9e6 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 9.0E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TSIB_0738 5a403d274419360640e126e7a058e9e6 138 Gene3D G3DSA:1.10.1220.10 10 50 1.4E-22 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TSIB_0738 5a403d274419360640e126e7a058e9e6 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.7 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 SUPERFAMILY SSF111038 2 129 5.89E-42 T 23-10-2018 IPR035917 YjbQ-like superfamily TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 130 1.9E-43 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 Gene3D G3DSA:2.60.120.460 1 132 1.1E-49 T 23-10-2018 IPR035917 YjbQ-like superfamily TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 PIRSF PIRSF004681 1 132 1.4E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_1654 830e1e04fb1a720e231eef0ddd399ab9 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 129 3.2E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 Gene3D G3DSA:3.40.50.920 205 335 1.5E-45 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 Pfam PF02780 Transketolase, C-terminal domain 206 327 1.2E-36 T 23-10-2018 IPR033248 Transketolase, C-terminal domain TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 Pfam PF02779 Transketolase, pyrimidine binding domain 7 181 1.3E-47 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 SUPERFAMILY SSF52922 201 335 7.72E-40 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 SUPERFAMILY SSF52518 6 216 1.07E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 Gene3D G3DSA:3.40.50.970 6 204 7.9E-86 T 23-10-2018 TSIB_1646 10482f1cbe8404b44e7338404714b5f0 335 SMART SM00861 8 183 9.8E-64 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 SUPERFAMILY SSF47917 446 553 1.2E-26 T 23-10-2018 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Gene3D G3DSA:2.40.50.100 113 184 2.1E-187 T 23-10-2018 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Gene3D G3DSA:1.10.1140.10 435 585 1.6E-58 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 SUPERFAMILY SSF52540 146 439 7.87E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 SUPERFAMILY SSF50615 1 68 7.22E-12 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Gene3D G3DSA:2.40.30.20 1 69 4.9E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 6.4E-48 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 4.5E-14 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 SMART SM00382 223 411 8.2E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Gene3D G3DSA:3.40.50.300 70 434 2.1E-187 T 23-10-2018 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.575 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1792 2fb552e3f73766db80c0446921edc1b7 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.7E-93 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SMART SM00493 2 129 3.9E-23 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0987 11245913e4016994993a5c576e45f539 1228 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 805 827 2.8E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region TSIB_0987 11245913e4016994993a5c576e45f539 1228 SMART SM00306 314 411 2.7E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF01131 DNA topoisomerase 156 315 2.7E-49 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF01131 DNA topoisomerase 827 1075 1.9E-73 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SMART SM00436 131 226 5.4E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:1.10.290.10 828 914 3.5E-54 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:1.10.290.10 281 315 2.1E-35 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SMART SM00305 786 832 4.9E-17 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF14528 LAGLIDADG-like domain 618 699 1.5E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:2.170.16.10 317 432 2.6E-10 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00379 Intein signature 525 537 1.2E-10 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00379 Intein signature 374 387 1.2E-10 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00379 Intein signature 803 820 1.2E-10 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00379 Intein signature 821 830 1.2E-10 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00379 Intein signature 619 631 1.2E-10 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SUPERFAMILY SSF56712 1 316 1.12E-82 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TSIB_0987 11245913e4016994993a5c576e45f539 1228 SUPERFAMILY SSF56712 827 1158 1.44E-72 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TSIB_0987 11245913e4016994993a5c576e45f539 1228 SUPERFAMILY SSF51294 316 826 1.96E-36 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SMART SM00437 271 1038 4.2E-100 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:2.170.16.10 733 825 5.5E-14 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 1217 43.659 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1002 1016 6.0E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 6.0E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 903 919 6.0E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 6.0E-22 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:3.40.50.140 1 154 4.2E-31 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 SUPERFAMILY SSF55608 606 717 3.4E-12 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0987 11245913e4016994993a5c576e45f539 1228 SUPERFAMILY SSF55608 521 606 3.61E-6 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:3.10.28.10 521 695 5.3E-15 T 23-10-2018 IPR027434 Homing endonuclease TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 1146 1183 9.4E-13 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:1.10.460.10 985 1077 3.5E-54 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:1.10.460.10 161 217 2.1E-35 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:2.60.510.20 915 984 3.5E-54 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Gene3D G3DSA:2.60.510.20 218 280 2.1E-35 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 316 386 6.5E-8 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF14890 Intein splicing domain 330 826 1.5E-26 T 23-10-2018 TSIB_0987 11245913e4016994993a5c576e45f539 1228 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 319 2.1E-147 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 TSIB_0987 11245913e4016994993a5c576e45f539 1228 Pfam PF01751 Toprim domain 3 139 6.6E-19 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0599 3b13e8556acde6587bd0942c4cb47556 587 Gene3D G3DSA:3.80.30.20 206 464 3.1E-24 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSIB_0599 3b13e8556acde6587bd0942c4cb47556 587 Pfam PF04055 Radical SAM superfamily 210 409 1.7E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0599 3b13e8556acde6587bd0942c4cb47556 587 SUPERFAMILY SSF102114 206 452 4.19E-26 T 23-10-2018 TSIB_0599 3b13e8556acde6587bd0942c4cb47556 587 SUPERFAMILY SSF47781 530 577 7.34E-5 T 23-10-2018 IPR010994 RuvA domain 2-like TSIB_0599 3b13e8556acde6587bd0942c4cb47556 587 SMART SM00729 206 456 7.7E-32 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0400 9bc967c17526a72929c5b1ef1f80abf4 348 SUPERFAMILY SSF53686 17 346 4.58E-65 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_0400 9bc967c17526a72929c5b1ef1f80abf4 348 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 342 2.4E-58 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_0400 9bc967c17526a72929c5b1ef1f80abf4 348 Gene3D G3DSA:3.40.50.1100 47 347 3.5E-76 T 23-10-2018 TSIB_0400 9bc967c17526a72929c5b1ef1f80abf4 348 Gene3D G3DSA:3.40.50.1100 92 185 3.5E-76 T 23-10-2018 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 Pfam PF01479 S4 domain 103 148 2.4E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 SUPERFAMILY SSF55174 9 160 1.31E-32 T 23-10-2018 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 33.969 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 Gene3D G3DSA:3.10.290.10 102 176 4.4E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 SMART SM00363 103 165 6.7E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 9.4E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0340 ce2e743887ca545607711c32ae7db33c 180 SMART SM01390 5 102 6.9E-8 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSIB_2051 b2e808cb9e21af9f1e33f85add22045e 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 359 5.0E-139 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSIB_2051 b2e808cb9e21af9f1e33f85add22045e 365 Gene3D G3DSA:3.90.1150.10 245 364 4.7E-42 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_2051 b2e808cb9e21af9f1e33f85add22045e 365 Gene3D G3DSA:3.40.640.10 1 243 1.1E-106 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_2051 b2e808cb9e21af9f1e33f85add22045e 365 SUPERFAMILY SSF53383 14 363 1.75E-131 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_2051 b2e808cb9e21af9f1e33f85add22045e 365 PIRSF PIRSF000390 1 364 4.9E-127 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 247 43.18 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 187 7.0E-37 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 PIRSF PIRSF002116 2 248 3.3E-97 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Pfam PF00900 Ribosomal family S4e 96 178 4.8E-24 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Gene3D G3DSA:2.30.30.30 184 248 8.1E-17 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 SUPERFAMILY SSF55174 52 96 6.02E-7 T 23-10-2018 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Pfam PF01479 S4 domain 53 91 9.0E-10 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Gene3D G3DSA:2.40.50.740 123 182 4.4E-17 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Gene3D G3DSA:3.10.290.40 1 118 4.3E-49 T 23-10-2018 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 SMART SM00363 43 107 1.4E-5 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0301 637e01dc0138aa6bd335fbe07f84a9a5 248 Pfam PF08071 RS4NT (NUC023) domain 4 40 2.4E-16 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 200 6.9E-76 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 Pfam PF01470 Pyroglutamyl peptidase 4 200 1.3E-76 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 3 200 36.525 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 1.2E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 1.2E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 1.2E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 5 28 1.2E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 1.2E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 Gene3D G3DSA:3.40.630.20 2 202 5.9E-76 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 PIRSF PIRSF015592 2 202 6.4E-76 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSIB_1014 219bcdd5c2baaf762c998fc3ef5e9b76 202 SUPERFAMILY SSF53182 3 200 1.83E-67 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSIB_1146 3a29f45d19ffeef268ef0405af2e0fae 278 Pfam PF04055 Radical SAM superfamily 23 163 2.7E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1146 3a29f45d19ffeef268ef0405af2e0fae 278 Gene3D G3DSA:3.20.20.70 8 253 1.2E-18 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1146 3a29f45d19ffeef268ef0405af2e0fae 278 SUPERFAMILY SSF102114 13 236 3.79E-24 T 23-10-2018 TSIB_1146 3a29f45d19ffeef268ef0405af2e0fae 278 SMART SM00729 16 219 3.0E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0895 c038348283d94ce8c4da521cd45cc574 243 Pfam PF02195 ParB-like nuclease domain 21 92 2.9E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TSIB_0895 c038348283d94ce8c4da521cd45cc574 243 SUPERFAMILY SSF110849 12 242 8.37E-59 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSIB_0895 c038348283d94ce8c4da521cd45cc574 243 SMART SM00470 19 114 5.1E-10 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TSIB_0895 c038348283d94ce8c4da521cd45cc574 243 Gene3D G3DSA:3.30.1760.10 98 228 7.9E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal TSIB_0895 c038348283d94ce8c4da521cd45cc574 243 Gene3D G3DSA:3.90.1530.10 17 239 7.9E-83 T 23-10-2018 TSIB_0746 1cc75d174f1ba630cd25537c557e92f7 260 Pfam PF13614 AAA domain 4 184 1.0E-52 T 23-10-2018 IPR025669 AAA domain TSIB_0746 1cc75d174f1ba630cd25537c557e92f7 260 SUPERFAMILY SSF52540 1 259 1.04E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0746 1cc75d174f1ba630cd25537c557e92f7 260 Gene3D G3DSA:3.40.50.300 2 260 1.3E-75 T 23-10-2018 TSIB_1519 6f8ac9010a89235be6959ec1834569a2 154 SUPERFAMILY SSF52833 7 151 2.57E-52 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1519 6f8ac9010a89235be6959ec1834569a2 154 Gene3D G3DSA:1.10.10.1590 3 65 8.5E-19 T 23-10-2018 TSIB_1519 6f8ac9010a89235be6959ec1834569a2 154 Gene3D G3DSA:3.40.30.10 66 154 1.7E-31 T 23-10-2018 TSIB_1519 6f8ac9010a89235be6959ec1834569a2 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 7 148 1.9E-53 T 23-10-2018 TSIB_1519 6f8ac9010a89235be6959ec1834569a2 154 PIRSF PIRSF000216 3 154 1.4E-58 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1593 89137b6240012392db899c3259cd4582 272 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 270 37.865 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TSIB_1593 89137b6240012392db899c3259cd4582 272 SMART SM00385 183 264 8.5E-12 T 23-10-2018 IPR013763 Cyclin-like TSIB_1593 89137b6240012392db899c3259cd4582 272 SMART SM00385 89 170 3.1E-9 T 23-10-2018 IPR013763 Cyclin-like TSIB_1593 89137b6240012392db899c3259cd4582 272 Pfam PF00382 Transcription factor TFIIB repeat 186 255 6.0E-18 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TSIB_1593 89137b6240012392db899c3259cd4582 272 Pfam PF00382 Transcription factor TFIIB repeat 92 161 1.3E-16 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TSIB_1593 89137b6240012392db899c3259cd4582 272 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 217 232 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 131 150 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 250 264 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 23 44 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 218 234 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 157 172 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 184 202 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 PRINTS PR00685 Transcription initiation factor IIB signature 10 23 5.6E-52 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TSIB_1593 89137b6240012392db899c3259cd4582 272 SUPERFAMILY SSF47954 83 176 3.4E-25 T 23-10-2018 IPR036915 Cyclin-like superfamily TSIB_1593 89137b6240012392db899c3259cd4582 272 Gene3D G3DSA:1.10.472.10 180 272 4.7E-27 T 23-10-2018 TSIB_1593 89137b6240012392db899c3259cd4582 272 SUPERFAMILY SSF47954 180 271 3.81E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily TSIB_1593 89137b6240012392db899c3259cd4582 272 Gene3D G3DSA:1.10.472.170 1 172 1.2E-50 T 23-10-2018 TSIB_1593 89137b6240012392db899c3259cd4582 272 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 123 138 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TSIB_0803 351c044e2ec138d0fcf9b049691f3e29 186 SUPERFAMILY SSF55729 16 164 1.33E-29 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_0803 351c044e2ec138d0fcf9b049691f3e29 186 Gene3D G3DSA:3.40.630.30 11 169 7.9E-51 T 23-10-2018 TSIB_0803 351c044e2ec138d0fcf9b049691f3e29 186 Pfam PF00583 Acetyltransferase (GNAT) family 29 151 1.7E-22 T 23-10-2018 IPR000182 GNAT domain TSIB_1184 1abe956062c92914acae3d14c54799a8 349 Gene3D G3DSA:3.90.650.10 172 340 8.5E-33 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_1184 1abe956062c92914acae3d14c54799a8 349 SUPERFAMILY SSF56042 172 334 4.78E-26 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_1184 1abe956062c92914acae3d14c54799a8 349 Gene3D G3DSA:3.30.1330.10 19 166 2.0E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_1184 1abe956062c92914acae3d14c54799a8 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 329 8.7E-17 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_1184 1abe956062c92914acae3d14c54799a8 349 SUPERFAMILY SSF55326 27 167 1.79E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_1184 1abe956062c92914acae3d14c54799a8 349 PIRSF PIRSF005644 22 348 1.8E-68 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TSIB_1184 1abe956062c92914acae3d14c54799a8 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 163 5.0E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0045 cfb462eb1fbdaadf6bfef80603aa5fde 132 Pfam PF05168 HEPN domain 5 120 1.6E-23 T 23-10-2018 IPR007842 HEPN domain TSIB_0045 cfb462eb1fbdaadf6bfef80603aa5fde 132 SUPERFAMILY SSF81593 7 122 3.3E-7 T 23-10-2018 TSIB_0045 cfb462eb1fbdaadf6bfef80603aa5fde 132 Gene3D G3DSA:1.20.120.330 2 125 1.5E-30 T 23-10-2018 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 Gene3D G3DSA:1.20.1250.20 2 381 4.6E-48 T 23-10-2018 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 Pfam PF07690 Major Facilitator Superfamily 7 335 2.2E-42 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 PRINTS PR01035 Tetracycline resistance protein signature 14 30 9.5E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 PRINTS PR01035 Tetracycline resistance protein signature 296 316 9.5E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 PRINTS PR01035 Tetracycline resistance protein signature 132 154 9.5E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSIB_0277 23b6050ba550fc5bfd5965d6eceba609 388 SUPERFAMILY SSF103473 7 387 2.22E-59 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_0454 46faadec50d4a8ddb0082839c06dc958 302 Pfam PF01171 PP-loop family 49 217 4.2E-10 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSIB_0454 46faadec50d4a8ddb0082839c06dc958 302 SUPERFAMILY SSF52402 24 243 5.95E-49 T 23-10-2018 TSIB_0454 46faadec50d4a8ddb0082839c06dc958 302 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 190 289 3.9E-22 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TSIB_0454 46faadec50d4a8ddb0082839c06dc958 302 Gene3D G3DSA:3.40.50.620 1 301 1.3E-89 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0454 46faadec50d4a8ddb0082839c06dc958 302 PIRSF PIRSF004976 1 296 6.7E-91 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 PIRSF PIRSF001435 14 229 1.4E-44 T 23-10-2018 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 ProSitePatterns PS01155 Endonuclease III family signature. 118 147 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 SUPERFAMILY SSF48150 20 224 8.32E-61 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 Hamap MF_00942 Endonuclease III [nth]. 16 226 33.232 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 Gene3D G3DSA:1.10.1670.10 33 220 4.2E-62 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 SMART SM00525 203 223 8.2E-6 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 SMART SM00478 52 202 1.4E-54 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 Gene3D G3DSA:1.10.340.30 35 148 4.2E-62 T 23-10-2018 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 50 185 4.9E-17 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSIB_0210 bb254c30e5bc287fddb0183ea73e97cd 233 Pfam PF00633 Helix-hairpin-helix motif 116 144 3.9E-7 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TSIB_1478 f54cd24d4003e431c92caab00012b9e6 175 Pfam PF04266 ASCH domain 6 87 2.9E-4 T 23-10-2018 IPR007374 ASCH domain TSIB_1478 f54cd24d4003e431c92caab00012b9e6 175 SUPERFAMILY SSF88697 3 141 2.73E-14 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1478 f54cd24d4003e431c92caab00012b9e6 175 SMART SM01022 5 108 9.7E-6 T 23-10-2018 IPR007374 ASCH domain TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 Gene3D G3DSA:3.30.1110.20 19 199 1.2E-155 T 23-10-2018 TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 5 458 43.39 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 12 449 1.6E-110 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 PIRSF PIRSF015883 1 458 3.8E-201 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 SUPERFAMILY SSF53613 10 457 5.54E-156 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 12 458 6.5E-216 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TSIB_1220 dc446955995839d79ebc5f14b1abaf20 461 Gene3D G3DSA:3.40.1190.20 14 448 1.2E-155 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 SMART SM00382 28 211 3.4E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 Gene3D G3DSA:3.40.50.300 1 238 1.8E-77 T 23-10-2018 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 Pfam PF00005 ABC transporter 19 161 2.1E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 327 2.4E-107 T 23-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 SUPERFAMILY SSF52540 4 244 8.54E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 SUPERFAMILY SSF50331 237 349 3.57E-13 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 Gene3D G3DSA:2.40.50.140 239 277 1.7E-6 T 23-10-2018 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 Gene3D G3DSA:2.40.50.100 278 309 1.7E-6 T 23-10-2018 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 Pfam PF08402 TOBE domain 275 349 1.1E-4 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSIB_0220 fdd109d286bfa95b750e4c579fdca718 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0681 8d17be7e83151b6160becc14150f33b0 124 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 3 123 1.6E-62 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 TSIB_1483 09294113df662e5eacb619149fbdb606 231 PIRSF PIRSF000883 1 231 9.0E-72 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 TSIB_1483 09294113df662e5eacb619149fbdb606 231 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 199 1.9E-20 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TSIB_1483 09294113df662e5eacb619149fbdb606 231 SUPERFAMILY SSF56300 1 231 7.6E-68 T 23-10-2018 TSIB_1483 09294113df662e5eacb619149fbdb606 231 Gene3D G3DSA:3.60.21.10 2 231 1.6E-72 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_1483 09294113df662e5eacb619149fbdb606 231 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 1.7E-32 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSIB_1307 128156a1c079b95fbf975249550964b6 121 Pfam PF03334 Na+/H+ antiporter subunit 9 98 8.6E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_1307 128156a1c079b95fbf975249550964b6 121 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 9 112 2.6E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_1491 2fda039a8fe3e7a2a4da3659747808e7 173 Gene3D G3DSA:3.90.320.10 14 173 3.0E-8 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSIB_1491 2fda039a8fe3e7a2a4da3659747808e7 173 Pfam PF01930 Domain of unknown function DUF83 17 172 1.1E-54 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 TSIB_1491 2fda039a8fe3e7a2a4da3659747808e7 173 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 16 172 1.5E-24 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 SMART SM00663 211 515 1.9E-205 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 1.1E-73 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:2.20.25.410 850 900 6.9E-22 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 6.9E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 1.1E-38 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:2.40.40.20 311 482 1.0E-80 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 5.6E-108 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:1.20.120.1280 235 284 6.1E-12 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:1.20.120.1280 1 120 2.2E-32 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:1.10.132.30 671 813 4.1E-43 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 SUPERFAMILY SSF64484 4 886 0.0 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:3.30.1490.180 354 418 1.0E-80 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Gene3D G3DSA:1.10.274.100 491 670 7.1E-61 T 23-10-2018 TSIB_0389 90cd313b2f5ef20dc79f435fc46e9124 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 2.6E-29 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_1467 1e8bdd8e54e829c14f042b86c66aee3e 281 Gene3D G3DSA:3.40.50.970 72 248 5.5E-31 T 23-10-2018 TSIB_1467 1e8bdd8e54e829c14f042b86c66aee3e 281 SUPERFAMILY SSF52518 19 261 1.72E-77 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1467 1e8bdd8e54e829c14f042b86c66aee3e 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 3.3E-37 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1272 487c2848d731a63d4c1e07ecfd5d2a44 244 Pfam PF01881 CRISPR associated protein Cas6 95 238 2.1E-33 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1272 487c2848d731a63d4c1e07ecfd5d2a44 244 Gene3D G3DSA:3.30.70.1900 123 240 1.9E-38 T 23-10-2018 TSIB_1272 487c2848d731a63d4c1e07ecfd5d2a44 244 PIRSF PIRSF005054 1 242 1.2E-60 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1272 487c2848d731a63d4c1e07ecfd5d2a44 244 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 2.0E-43 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1272 487c2848d731a63d4c1e07ecfd5d2a44 244 Gene3D G3DSA:3.30.70.1890 1 121 1.8E-39 T 23-10-2018 TSIB_1276 a392bffd7e4cd7133555cad13f91e7d9 180 PIRSF PIRSF006019 12 169 1.7E-55 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSIB_1276 a392bffd7e4cd7133555cad13f91e7d9 180 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 131 6.1E-28 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSIB_1276 a392bffd7e4cd7133555cad13f91e7d9 180 Gene3D G3DSA:3.40.140.10 18 167 9.7E-47 T 23-10-2018 TSIB_1276 a392bffd7e4cd7133555cad13f91e7d9 180 SUPERFAMILY SSF53927 22 152 8.86E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSIB_1276 a392bffd7e4cd7133555cad13f91e7d9 180 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 Pfam PF00380 Ribosomal protein S9/S16 16 143 5.3E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 11 143 6.2E-59 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 11 143 36.521 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 SUPERFAMILY SSF54211 11 143 3.41E-33 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 ProSitePatterns PS00360 Ribosomal protein S9 signature. 76 94 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TSIB_0345 158e28cdbb8ffa5dddfce58b8643f817 143 Gene3D G3DSA:3.30.230.10 7 143 2.8E-49 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 SUPERFAMILY SSF53383 32 443 4.3E-111 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 Gene3D G3DSA:3.40.640.10 71 341 1.2E-138 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 Gene3D G3DSA:3.90.1150.10 17 438 1.2E-138 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 Pfam PF00202 Aminotransferase class-III 35 442 3.1E-97 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 PIRSF PIRSF000521 136 445 2.0E-30 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1005 a0689e256cb861291c210dbf2b3dd64c 458 PIRSF PIRSF000521 2 140 1.7E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 SUPERFAMILY SSF89447 53 86 4.88E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 55 84 1.9E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 PIRSF PIRSF019240 1 95 8.4E-21 T 23-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 Gene3D G3DSA:2.10.260.10 1 93 1.5E-31 T 23-10-2018 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 SMART SM00966 55 96 9.8E-5 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 SMART SM00966 9 53 52.0 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 56 84 3.3E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSIB_2055 9892eaec9c2a23e6670b0fd58486fa8f 98 SUPERFAMILY SSF89447 7 40 9.94E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSIB_0723 5bdc1faa71e1d26f964923d134bf02fe 219 Gene3D G3DSA:1.10.10.580 148 217 7.3E-33 T 23-10-2018 IPR023093 ScpA-like, C-terminal TSIB_0723 5bdc1faa71e1d26f964923d134bf02fe 219 Pfam PF02616 Segregation and condensation protein ScpA 18 158 9.5E-11 T 23-10-2018 IPR003768 Segregation and condensation protein A TSIB_0723 5bdc1faa71e1d26f964923d134bf02fe 219 Pfam PF04824 Conserved region of Rad21 / Rec8 like protein 183 215 2.1E-5 T 23-10-2018 IPR006909 Rad21/Rec8-like protein, C-terminal, eukaryotic GO:0000228 TSIB_1152 486ef6ad5bb812ce081f5ffa3296cfa3 177 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 171 1.4E-13 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 Gene3D G3DSA:3.40.50.970 187 386 1.1E-69 T 23-10-2018 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 565 9.9E-203 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 Gene3D G3DSA:3.40.50.920 458 570 7.7E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 Gene3D G3DSA:3.40.920.10 5 186 2.2E-26 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 438 8.4E-56 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 SUPERFAMILY SSF53323 8 222 4.45E-37 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 SUPERFAMILY SSF52922 463 567 3.85E-14 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 SUPERFAMILY SSF52518 200 449 1.96E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1902 c8612ef963a1edd8bb3d645bdd9421fb 570 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 1.7E-30 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 SUPERFAMILY SSF51735 4 190 9.2E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 Gene3D G3DSA:3.30.360.10 123 322 3.9E-75 T 23-10-2018 TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 122 1.0E-28 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 241 1.7E-6 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 Gene3D G3DSA:3.40.50.720 4 309 3.9E-75 T 23-10-2018 TSIB_1682 9b2d5bd99fc54bf227cf6e36fbdfa4e5 341 SUPERFAMILY SSF55347 157 302 3.6E-18 T 23-10-2018 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 Gene3D G3DSA:3.30.200.20 51 152 4.3E-12 T 23-10-2018 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 Pfam PF01163 RIO1 family 65 245 6.7E-54 T 23-10-2018 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 Gene3D G3DSA:1.10.510.10 156 257 2.3E-26 T 23-10-2018 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 SMART SM00090 23 257 3.1E-116 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 SUPERFAMILY SSF56112 54 239 1.37E-24 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TSIB_1107 370fddb80f2a6cf549ba8e7f2b1edb65 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TSIB_0980 956957ef982b4c5e429a0e5b4f6d92bd 73 SUPERFAMILY SSF50346 5 69 2.04E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TSIB_0980 956957ef982b4c5e429a0e5b4f6d92bd 73 Pfam PF05239 PRC-barrel domain 6 70 6.4E-13 T 23-10-2018 IPR027275 PRC-barrel domain TSIB_0980 956957ef982b4c5e429a0e5b4f6d92bd 73 Gene3D G3DSA:2.30.30.240 6 72 1.3E-6 T 23-10-2018 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 8 200 42.686 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 Pfam PF00827 Ribosomal L15 9 196 8.6E-88 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 ProSitePatterns PS01194 Ribosomal protein L15e signature. 53 76 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 SMART SM01384 9 198 6.9E-130 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 SUPERFAMILY SSF54189 8 199 7.19E-86 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1186 10ba85b3c91de3a3f24a692ab183c2c1 201 Gene3D G3DSA:3.40.1120.10 7 200 1.1E-87 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 SUPERFAMILY SSF55267 9 80 3.92E-17 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 TIGRFAM TIGR00324 endA: tRNA-intron lyase 23 172 9.4E-35 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 Gene3D G3DSA:3.40.1170.20 11 77 5.7E-15 T 23-10-2018 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 Gene3D G3DSA:3.40.1350.10 83 175 3.7E-30 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 9 175 31.6 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 10 73 9.4E-18 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 PIRSF PIRSF005285 12 175 7.4E-60 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 SUPERFAMILY SSF53032 83 171 8.76E-28 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TSIB_0099 939041a6c6b90276d77c2d3f6a83a455 175 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 84 167 2.6E-29 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 Gene3D G3DSA:3.40.50.1360 5 221 3.7E-89 T 23-10-2018 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 SUPERFAMILY SSF100950 2 150 1.07E-45 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 1.5E-82 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 1.2E-65 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 SUPERFAMILY SSF75445 131 207 1.44E-24 T 23-10-2018 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.595 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSIB_0900 7fac8a47cd9eaf88b99b5498bd95ba5a 227 Gene3D G3DSA:3.30.70.260 127 205 3.7E-89 T 23-10-2018 TSIB_1854 2729a056ea7a1ed602f9c4480d0c3896 92 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 6 92 6.2E-25 T 23-10-2018 IPR010038 MoaD, archaeal-type TSIB_1854 2729a056ea7a1ed602f9c4480d0c3896 92 Pfam PF02597 ThiS family 8 92 4.0E-17 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1854 2729a056ea7a1ed602f9c4480d0c3896 92 Gene3D G3DSA:3.10.20.30 1 92 5.7E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1854 2729a056ea7a1ed602f9c4480d0c3896 92 SUPERFAMILY SSF54285 4 89 7.85E-21 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_0343 66199c546cf5a51369e1e26899dabc56 130 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 14 130 30.404 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea TSIB_0343 66199c546cf5a51369e1e26899dabc56 130 Gene3D G3DSA:3.100.10.10 15 130 2.6E-39 T 23-10-2018 TSIB_0343 66199c546cf5a51369e1e26899dabc56 130 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 21 129 7.6E-16 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TSIB_0343 66199c546cf5a51369e1e26899dabc56 130 SUPERFAMILY SSF52080 15 129 6.93E-30 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TSIB_1905 3295fb96d1f5e47f996f6a22d0fb8a29 202 SUPERFAMILY SSF54862 40 133 2.65E-21 T 23-10-2018 TSIB_1905 3295fb96d1f5e47f996f6a22d0fb8a29 202 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1905 3295fb96d1f5e47f996f6a22d0fb8a29 202 Pfam PF12838 4Fe-4S dicluster domain 60 110 2.7E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1905 3295fb96d1f5e47f996f6a22d0fb8a29 202 Gene3D G3DSA:3.30.70.3270 39 160 3.3E-23 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 Gene3D G3DSA:3.50.50.60 44 242 3.5E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 293 3.0E-59 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 Gene3D G3DSA:3.50.50.60 321 442 3.5E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.3E-27 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-27 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.3E-27 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.3E-27 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.3E-27 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 Gene3D G3DSA:3.50.50.60 5 314 3.5E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 2.3E-20 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 SUPERFAMILY SSF51905 3 344 2.97E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.2E-21 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 3.2E-21 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 3.2E-21 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 3.2E-21 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 3.2E-21 T 23-10-2018 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 437 1.9E-184 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 TSIB_0263 e04d2bf0f5f74e0431e4c1bc0650bac9 442 SUPERFAMILY SSF55424 321 439 5.84E-32 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 320 1.2E-24 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 Pfam PF00005 ABC transporter 26 180 7.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 SUPERFAMILY SSF52540 5 251 4.86E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 Gene3D G3DSA:3.40.50.300 2 322 9.1E-96 T 23-10-2018 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 292 8.5E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1055 2e84b583435cb02d88739079b115cd3b 322 SMART SM00382 34 229 2.2E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1695 2c83f85862fc4892bfe2a3cf60b23a47 70 SUPERFAMILY SSF54862 6 67 8.39E-16 T 23-10-2018 TSIB_1695 2c83f85862fc4892bfe2a3cf60b23a47 70 Pfam PF13187 4Fe-4S dicluster domain 15 64 2.8E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1695 2c83f85862fc4892bfe2a3cf60b23a47 70 Gene3D G3DSA:3.30.70.20 9 66 2.8E-14 T 23-10-2018 TSIB_1695 2c83f85862fc4892bfe2a3cf60b23a47 70 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0801 50c90b2d0170d45d7e6c8f5e0a61eea6 135 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 48 4.9E-14 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TSIB_0801 50c90b2d0170d45d7e6c8f5e0a61eea6 135 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 51 113 3.0E-21 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TSIB_0801 50c90b2d0170d45d7e6c8f5e0a61eea6 135 Gene3D G3DSA:1.10.12.20 2 50 1.8E-9 T 23-10-2018 TSIB_0801 50c90b2d0170d45d7e6c8f5e0a61eea6 135 SUPERFAMILY SSF50249 8 117 2.74E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 Pfam PF02834 LigT like Phosphoesterase 7 92 1.5E-19 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 Pfam PF02834 LigT like Phosphoesterase 99 175 5.8E-12 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 183 5.0E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 Gene3D G3DSA:3.90.1140.10 1 185 2.4E-66 T 23-10-2018 TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 183 27.551 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSIB_1140 e9b7dbb517240a8c32421058b29f8883 185 SUPERFAMILY SSF55144 1 184 3.49E-44 T 23-10-2018 IPR009097 Cyclic phosphodiesterase TSIB_1861 608d96999b4f7962b9a9ee81253049a0 233 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 179 216 3.5E-6 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TSIB_1861 608d96999b4f7962b9a9ee81253049a0 233 PIRSF PIRSF006578 1 217 6.2E-48 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E TSIB_1861 608d96999b4f7962b9a9ee81253049a0 233 SUPERFAMILY SSF143555 13 181 1.07E-48 T 23-10-2018 TSIB_1861 608d96999b4f7962b9a9ee81253049a0 233 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 1.6E-36 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain TSIB_1861 608d96999b4f7962b9a9ee81253049a0 233 Gene3D G3DSA:3.30.1330.130 4 173 4.7E-43 T 23-10-2018 TSIB_1252 cda22bea0ef73becf742cba52307a9a0 221 Pfam PF06510 Protein of unknown function (DUF1102) 56 209 5.2E-42 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 62 78 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 41 53 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 374 396 2.5E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 408 420 2.5E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 60 78 2.5E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 38 54 2.5E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 90 109 2.5E-36 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 Gene3D G3DSA:3.30.260.10 148 406 5.0E-215 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 SUPERFAMILY SSF54849 150 406 2.01E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 90 98 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 36 526 7.4E-184 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 SUPERFAMILY SSF48592 18 524 1.83E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 Gene3D G3DSA:3.50.7.10 219 370 5.0E-215 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 SUPERFAMILY SSF52029 213 379 2.72E-61 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 9 526 1.3E-239 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TSIB_1538 ea554528cefe92e9bd55e72f04116aaf 550 Gene3D G3DSA:1.10.560.10 29 523 5.0E-215 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSIB_0590 2205d7e8ff5bb1716409aa1e718ae20d 283 Gene3D G3DSA:3.40.50.300 1 231 2.0E-58 T 23-10-2018 TSIB_0590 2205d7e8ff5bb1716409aa1e718ae20d 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0590 2205d7e8ff5bb1716409aa1e718ae20d 283 SMART SM00382 28 214 4.9E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0590 2205d7e8ff5bb1716409aa1e718ae20d 283 Pfam PF00005 ABC transporter 20 157 1.4E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0590 2205d7e8ff5bb1716409aa1e718ae20d 283 SUPERFAMILY SSF52540 2 217 1.43E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 Gene3D G3DSA:3.40.800.10 5 283 2.2E-80 T 23-10-2018 TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 ProSitePatterns PS01053 Arginase family signature. 203 224 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 PIRSF PIRSF036979 4 278 1.0E-75 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 TIGRFAM TIGR01230 agmatinase: agmatinase 9 272 2.4E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 Pfam PF00491 Arginase family 13 271 1.7E-75 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_1067 6c81fa3e6759ac8fd5f27c41bbcb5b1b 285 SUPERFAMILY SSF52768 6 276 3.24E-76 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TSIB_1194 74a0413c00d04334d5574520a1c253f0 423 SUPERFAMILY SSF56801 72 356 7.33E-19 T 23-10-2018 TSIB_1194 74a0413c00d04334d5574520a1c253f0 423 Pfam PF00501 AMP-binding enzyme 80 232 1.0E-7 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSIB_1194 74a0413c00d04334d5574520a1c253f0 423 ProSitePatterns PS00455 Putative AMP-binding domain signature. 79 90 - T 23-10-2018 IPR020845 AMP-binding, conserved site TSIB_1194 74a0413c00d04334d5574520a1c253f0 423 Gene3D G3DSA:3.40.50.12780 5 310 1.7E-21 T 23-10-2018 TSIB_0282 b1ec7522e35e7dd7b5a14d7c5df69080 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 320 331 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0282 b1ec7522e35e7dd7b5a14d7c5df69080 375 Pfam PF17179 4Fe-4S dicluster domain 241 334 3.1E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0282 b1ec7522e35e7dd7b5a14d7c5df69080 375 SUPERFAMILY SSF46548 226 340 3.77E-11 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_0282 b1ec7522e35e7dd7b5a14d7c5df69080 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 241 252 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 Gene3D G3DSA:3.30.70.20 21 73 1.1E-6 T 23-10-2018 TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 5.9E-11 T 23-10-2018 TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 Gene3D G3DSA:3.30.70.20 74 105 2.1E-8 T 23-10-2018 TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 SUPERFAMILY SSF54862 25 103 3.26E-24 T 23-10-2018 TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1380 c6ac47068320f5aa10fae0f104eea1e6 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 28 104 4.2E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TSIB_1402 ab92ca4256f872e3cac148e66e95cc5b 144 SUPERFAMILY SSF52242 5 132 9.16E-48 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSIB_1402 ab92ca4256f872e3cac148e66e95cc5b 144 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 2.8E-59 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSIB_1402 ab92ca4256f872e3cac148e66e95cc5b 144 Gene3D G3DSA:3.40.50.280 1 144 5.3E-56 T 23-10-2018 TSIB_1402 ab92ca4256f872e3cac148e66e95cc5b 144 Pfam PF02310 B12 binding domain 8 121 8.2E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 4 225 5.3E-89 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 PIRSF PIRSF039123 3 228 1.7E-82 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 4 223 1.7E-84 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 SUPERFAMILY SSF52402 3 224 1.7E-75 T 23-10-2018 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 Gene3D G3DSA:3.40.50.620 1 140 1.5E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 Pfam PF01902 Diphthamide synthase 4 223 1.7E-83 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 7 221 8.8E-91 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding TSIB_1787 213f4ff3a9a55a712bb4e182d9d9c2b9 229 Gene3D G3DSA:3.90.1490.10 141 229 5.3E-33 T 23-10-2018 TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 SUPERFAMILY SSF54631 5 124 4.04E-16 T 23-10-2018 TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 SUPERFAMILY SSF54631 127 261 1.5E-31 T 23-10-2018 TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Gene3D G3DSA:3.10.580.10 208 304 4.4E-11 T 23-10-2018 TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Gene3D G3DSA:3.10.580.10 125 207 3.5E-19 T 23-10-2018 TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Pfam PF00571 CBS domain 211 261 1.5E-8 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Pfam PF00571 CBS domain 132 183 8.1E-17 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Pfam PF00571 CBS domain 6 55 8.5E-4 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 PIRSF PIRSF036983 2 389 1.1E-126 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 SMART SM00116 217 265 4.3E-7 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 SMART SM00116 75 123 50.0 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 SMART SM00116 139 187 6.9E-10 T 23-10-2018 IPR000644 CBS domain TSIB_1314 957bcb41a5b332a609bb20d98df152af 390 Gene3D G3DSA:3.10.580.10 4 124 5.7E-15 T 23-10-2018 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 Pfam PF00209 Sodium:neurotransmitter symporter family 166 496 1.4E-28 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 3.0E-23 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.0E-17 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 317 336 1.0E-17 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.0E-17 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 399 419 1.0E-17 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_1111 b903bbd85f762ad32903bb9d29a2ba9b 522 SUPERFAMILY SSF161070 4 496 2.09E-108 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TSIB_1038 5d5f1983d77a60545590d46b7249bfe0 169 Gene3D G3DSA:3.40.50.11570 1 168 1.4E-47 T 23-10-2018 TSIB_1038 5d5f1983d77a60545590d46b7249bfe0 169 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 2 165 2.9E-44 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_0091 e32e0f8c42c65580d715e7dfec7c5892 348 Pfam PF00535 Glycosyl transferase family 2 39 199 7.1E-32 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_0091 e32e0f8c42c65580d715e7dfec7c5892 348 Gene3D G3DSA:3.90.550.10 28 241 5.8E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0091 e32e0f8c42c65580d715e7dfec7c5892 348 SUPERFAMILY SSF53448 25 286 1.23E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 Gene3D G3DSA:3.20.20.100 10 328 1.3E-96 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 PRINTS PR00069 Aldo-keto reductase signature 45 69 4.0E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 PRINTS PR00069 Aldo-keto reductase signature 104 122 4.0E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 PRINTS PR00069 Aldo-keto reductase signature 237 261 4.0E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 SUPERFAMILY SSF51430 6 306 3.4E-91 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSIB_1209 41fac723ec0d087ef5d1ed8f83e921b7 394 Pfam PF00248 Aldo/keto reductase family 18 302 3.3E-73 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 324 37.438 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 Pfam PF00814 Glycoprotease family 22 292 1.7E-97 T 23-10-2018 IPR000905 Gcp-like domain TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 Gene3D G3DSA:3.30.420.40 4 299 8.3E-117 T 23-10-2018 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 SUPERFAMILY SSF53067 1 292 1.44E-37 T 23-10-2018 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 6.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 3.3E-154 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 Gene3D G3DSA:3.30.420.40 122 278 8.3E-117 T 23-10-2018 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TSIB_1839 88c05301d1666a61bdf0f7ebbf105ef8 324 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 8.5E-105 T 23-10-2018 IPR017861 Kae1/TsaD family TSIB_0570 ff193921509c45556be59e97198cacf2 278 Gene3D G3DSA:3.20.20.100 11 275 9.1E-90 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSIB_0570 ff193921509c45556be59e97198cacf2 278 Pfam PF00248 Aldo/keto reductase family 21 273 2.8E-61 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSIB_0570 ff193921509c45556be59e97198cacf2 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TSIB_0570 ff193921509c45556be59e97198cacf2 278 SUPERFAMILY SSF51430 16 273 8.25E-77 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSIB_0570 ff193921509c45556be59e97198cacf2 278 PRINTS PR00069 Aldo-keto reductase signature 105 123 2.4E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_0570 ff193921509c45556be59e97198cacf2 278 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.4E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_0570 ff193921509c45556be59e97198cacf2 278 PRINTS PR00069 Aldo-keto reductase signature 49 73 2.4E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_0570 ff193921509c45556be59e97198cacf2 278 PRINTS PR00069 Aldo-keto reductase signature 212 236 2.4E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_0570 ff193921509c45556be59e97198cacf2 278 PIRSF PIRSF000097 9 276 1.3E-40 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSIB_1330 f48ed6e34f56b3e1ceda18240123b93c 63 SUPERFAMILY SSF47598 3 46 4.34E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSIB_1330 f48ed6e34f56b3e1ceda18240123b93c 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 1.2E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TSIB_1330 f48ed6e34f56b3e1ceda18240123b93c 63 Gene3D G3DSA:1.10.1220.10 11 46 1.2E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 Gene3D G3DSA:3.40.50.300 575 796 1.3E-45 T 23-10-2018 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 Gene3D G3DSA:3.40.50.300 1 302 1.3E-14 T 23-10-2018 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 531 774 1.5E-8 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 Pfam PF04423 Rad50 zinc hook motif 365 411 1.3E-9 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 Gene3D G3DSA:1.10.287.510 335 444 2.6E-15 T 23-10-2018 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 SUPERFAMILY SSF75712 337 434 2.09E-13 T 23-10-2018 TSIB_0555 3c84eaaceb6d4e6c37f0dbd02f213b12 803 SUPERFAMILY SSF52540 571 787 1.8E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 Gene3D G3DSA:3.30.70.100 1 91 2.0E-37 T 23-10-2018 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 Pfam PF00708 Acylphosphatase 7 88 1.6E-26 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 SUPERFAMILY SSF54975 1 90 8.94E-30 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 PRINTS PR00112 Acylphosphatase signature 26 51 3.1E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 PRINTS PR00112 Acylphosphatase signature 5 20 3.1E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1163 1e7fdbbe8bc2a8f2ee7e2028ff1ce3a7 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 SUPERFAMILY SSF56726 76 376 1.23E-77 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 44 64 2.6E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 171 189 2.6E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 351 374 2.6E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 118 135 2.6E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 227 247 2.6E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 Pfam PF04406 Type IIB DNA topoisomerase 78 147 4.8E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 142 157 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 253 269 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 124 141 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 221 242 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 102 113 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 197 214 1.3E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 Gene3D G3DSA:1.10.10.10 8 150 7.9E-50 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1104 3f44de3a884461840d848a061dce4c22 381 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 12 380 39.998 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TSIB_1104 3f44de3a884461840d848a061dce4c22 381 Gene3D G3DSA:3.40.1360.10 151 380 6.2E-65 T 23-10-2018 TSIB_1089 a26ec79d143363d11d534aa3c49bee6d 189 Pfam PF04266 ASCH domain 4 102 1.1E-19 T 23-10-2018 IPR007374 ASCH domain TSIB_1089 a26ec79d143363d11d534aa3c49bee6d 189 SUPERFAMILY SSF88697 2 102 2.61E-20 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1089 a26ec79d143363d11d534aa3c49bee6d 189 SMART SM01022 4 103 6.6E-24 T 23-10-2018 IPR007374 ASCH domain TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 Pfam PF02421 Ferrous iron transport protein B 20 174 1.3E-62 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 42 60 1.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 21 41 1.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 Pfam PF07664 Ferrous iron transport protein B C terminus 474 525 8.0E-18 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 SUPERFAMILY SSF52540 21 194 6.12E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 25 648 8.0E-186 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 Gene3D G3DSA:3.40.50.300 17 185 3.7E-46 T 23-10-2018 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 Pfam PF07670 Nucleoside recognition 369 463 1.3E-14 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TSIB_0502 646a9062392f5177a4684dc9d0cba88a 681 Pfam PF07670 Nucleoside recognition 530 651 1.6E-26 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TSIB_1022 cc3e62df8f23270d521c7544d354b6cf 343 SUPERFAMILY SSF103473 8 134 6.15E-5 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1022 cc3e62df8f23270d521c7544d354b6cf 343 Pfam PF13429 Tetratricopeptide repeat 163 310 8.6E-7 T 23-10-2018 TSIB_1022 cc3e62df8f23270d521c7544d354b6cf 343 SUPERFAMILY SSF48452 121 325 4.49E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1022 cc3e62df8f23270d521c7544d354b6cf 343 Gene3D G3DSA:1.25.40.10 109 335 1.4E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Gene3D G3DSA:3.30.1330.30 274 415 2.0E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Gene3D G3DSA:3.30.960.10 1 135 3.6E-53 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Pfam PF03464 eRF1 domain 2 140 271 1.1E-46 T 23-10-2018 IPR005141 eRF1 domain 2 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 SUPERFAMILY SSF55481 3 135 5.49E-48 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Pfam PF03465 eRF1 domain 3 276 414 2.7E-34 T 23-10-2018 IPR005142 eRF1 domain 3 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.175 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 SUPERFAMILY SSF55315 273 414 7.65E-41 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Pfam PF03463 eRF1 domain 1 16 133 1.2E-10 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 SMART SM01194 1 135 2.1E-33 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 SUPERFAMILY SSF53137 138 270 2.92E-43 T 23-10-2018 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 413 2.8E-178 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1927 100c903b9a000a0b467cdc4af9586a8d 415 Gene3D G3DSA:3.30.420.60 137 271 1.5E-53 T 23-10-2018 TSIB_1358 77f3d982591a3882fd004345fb559957 130 Pfam PF04475 Protein of unknown function (DUF555) 3 104 1.4E-41 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TSIB_1358 77f3d982591a3882fd004345fb559957 130 PIRSF PIRSF016934 1 126 6.5E-56 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TSIB_1358 77f3d982591a3882fd004345fb559957 130 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 91 4.0E-41 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TSIB_1358 77f3d982591a3882fd004345fb559957 130 Hamap MF_01223 UPF0212 protein . 1 112 33.256 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 SMART SM00881 9 108 6.9E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 Gene3D G3DSA:3.40.50.261 300 464 6.3E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 Pfam PF13380 CoA binding domain 13 142 1.2E-19 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 Gene3D G3DSA:3.40.50.261 138 299 6.3E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 SUPERFAMILY SSF52210 139 298 7.59E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 SUPERFAMILY SSF51735 6 137 8.12E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 7 455 1.6E-183 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 SUPERFAMILY SSF52210 302 458 1.14E-32 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 296 1.2E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSIB_0529 94a704be5f424afe4ede2cadfb49441c 465 Gene3D G3DSA:3.40.50.720 4 137 3.6E-44 T 23-10-2018 TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 Gene3D G3DSA:2.10.240.10 194 231 1.1E-10 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 Pfam PF00970 Oxidoreductase FAD-binding domain 7 90 1.1E-4 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 SUPERFAMILY SSF52343 87 230 1.02E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 Gene3D G3DSA:3.40.50.80 94 193 4.7E-6 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 PIRSF PIRSF006816 4 234 4.1E-43 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 Gene3D G3DSA:2.40.30.10 5 90 1.0E-13 T 23-10-2018 TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 SUPERFAMILY SSF63380 10 92 5.55E-14 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSIB_0442 bb03f37b11f93b68c9855b5adb961261 235 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 194 230 3.6E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 Pfam PF01850 PIN domain 8 120 6.3E-7 T 23-10-2018 IPR002716 PIN domain TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 Pfam PF00437 Type II/IV secretion system protein 216 373 1.1E-7 T 23-10-2018 IPR001482 Type II/IV secretion system protein TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 SMART SM00670 5 118 2.6E-26 T 23-10-2018 IPR002716 PIN domain TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 Gene3D G3DSA:3.40.50.300 242 452 2.9E-18 T 23-10-2018 TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 SUPERFAMILY SSF88723 4 134 1.09E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 Pfam PF00013 KH domain 496 525 2.6E-4 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 SUPERFAMILY SSF52540 140 442 8.72E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 SUPERFAMILY SSF54814 478 524 2.81E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_1405 e6cc413a71f93f6d162a8863ac45a01f 605 Gene3D G3DSA:3.40.50.1010 3 130 4.4E-35 T 23-10-2018 TSIB_0098 5383dff9d989bfcd64bbb9f10e2db373 120 SUPERFAMILY SSF55729 5 115 1.44E-34 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_0098 5383dff9d989bfcd64bbb9f10e2db373 120 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 6 109 7.1E-33 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TSIB_0098 5383dff9d989bfcd64bbb9f10e2db373 120 Pfam PF00583 Acetyltransferase (GNAT) family 5 90 2.8E-26 T 23-10-2018 IPR000182 GNAT domain TSIB_0098 5383dff9d989bfcd64bbb9f10e2db373 120 PIRSF PIRSF037663 1 109 2.0E-12 T 23-10-2018 IPR017255 Acetyltransferase, GNAT, predicted TSIB_0098 5383dff9d989bfcd64bbb9f10e2db373 120 Gene3D G3DSA:3.40.630.30 2 117 4.0E-42 T 23-10-2018 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 SMART SM00652 59 142 9.5E-39 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 SUPERFAMILY SSF50249 46 145 8.0E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 Pfam PF01176 Translation initiation factor 1A / IF-1 63 126 1.1E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 52 140 2.9E-31 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 Gene3D G3DSA:2.40.50.140 38 151 6.4E-39 T 23-10-2018 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 84 141 3.0E-15 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TSIB_1108 2d35de18be848aad296b4a8a5b549979 152 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 48 142 27.057 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TSIB_0920 32b32b9c26840e29ec68dd364e07b4ad 190 Gene3D G3DSA:3.40.50.300 1 181 1.1E-45 T 23-10-2018 TSIB_0920 32b32b9c26840e29ec68dd364e07b4ad 190 Pfam PF13207 AAA domain 6 132 1.3E-21 T 23-10-2018 TSIB_0920 32b32b9c26840e29ec68dd364e07b4ad 190 Hamap MF_01111 UPF0200 protein . 2 182 31.489 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related TSIB_0920 32b32b9c26840e29ec68dd364e07b4ad 190 SUPERFAMILY SSF52540 1 180 4.67E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1828 8e5f7e90bae158c806106bc150638cb3 391 Pfam PF13173 AAA domain 48 178 2.3E-23 T 23-10-2018 TSIB_1828 8e5f7e90bae158c806106bc150638cb3 391 Gene3D G3DSA:3.40.50.300 22 129 3.1E-5 T 23-10-2018 TSIB_1828 8e5f7e90bae158c806106bc150638cb3 391 SUPERFAMILY SSF52540 43 225 9.42E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 Gene3D G3DSA:3.30.70.100 248 340 2.2E-28 T 23-10-2018 TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 SUPERFAMILY SSF50182 182 246 3.27E-18 T 23-10-2018 IPR010920 LSM domain superfamily TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 SUPERFAMILY SSF82689 250 346 4.18E-32 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 Pfam PF00924 Mechanosensitive ion channel 137 336 4.6E-61 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 Gene3D G3DSA:2.30.30.60 197 246 8.1E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 SUPERFAMILY SSF82861 97 180 6.8E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSIB_0072 4621b0cfd2acd2b1fcbec98fea1d3ab1 356 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 211 245 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.5E-18 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.5E-18 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.5E-18 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 1.5E-18 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 312 3.9E-31 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 Gene3D G3DSA:3.50.50.60 124 258 1.0E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 SUPERFAMILY SSF51905 1 325 1.11E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.9E-15 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 1.9E-15 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 1.9E-15 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 1.9E-15 T 23-10-2018 TSIB_0770 345c25c0cb1fbdffa3db40bb3e877e52 418 Gene3D G3DSA:3.50.50.60 6 301 1.0E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.464 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 Gene3D G3DSA:3.90.940.20 1 82 2.0E-34 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 SUPERFAMILY SSF55287 8 80 4.58E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 14 79 4.0E-20 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0387 8fa4d0c486b5a3c00bb8396eabc095f0 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 9 79 4.9E-32 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_1673 1c34b40f3ae70faacec7b931ed5d69c6 128 SUPERFAMILY SSF54637 13 119 4.68E-26 T 23-10-2018 IPR029069 HotDog domain superfamily TSIB_1673 1c34b40f3ae70faacec7b931ed5d69c6 128 Gene3D G3DSA:3.10.129.10 1 128 2.1E-43 T 23-10-2018 TSIB_1673 1c34b40f3ae70faacec7b931ed5d69c6 128 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 112 6.2E-10 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSIB_1673 1c34b40f3ae70faacec7b931ed5d69c6 128 Pfam PF03061 Thioesterase superfamily 40 112 7.7E-9 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 Pfam PF00281 Ribosomal protein L5 16 68 4.0E-21 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 SUPERFAMILY SSF55282 15 180 6.36E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 PIRSF PIRSF002161 2 180 8.6E-56 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 2.8E-25 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 Gene3D G3DSA:3.30.1440.10 10 183 1.6E-70 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0302 5a6d9218288b9db824de8b030e68312c 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.262 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0838 cdb85134aed5ef1020e862e07ea30888 187 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 24 168 1.4E-62 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TSIB_0838 cdb85134aed5ef1020e862e07ea30888 187 Gene3D G3DSA:3.40.50.1010 26 169 1.9E-8 T 23-10-2018 TSIB_0838 cdb85134aed5ef1020e862e07ea30888 187 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 36 108 7.0E-29 T 23-10-2018 TSIB_0838 cdb85134aed5ef1020e862e07ea30888 187 Pfam PF01936 NYN domain 35 166 1.4E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TSIB_1131 7470811da8bed4bee06b2e7c4ed5c499 290 Pfam PF00892 EamA-like transporter family 152 282 8.6E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1131 7470811da8bed4bee06b2e7c4ed5c499 290 Pfam PF00892 EamA-like transporter family 16 144 1.1E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1131 7470811da8bed4bee06b2e7c4ed5c499 290 SUPERFAMILY SSF103481 191 283 3.79E-9 T 23-10-2018 TSIB_1131 7470811da8bed4bee06b2e7c4ed5c499 290 SUPERFAMILY SSF103481 51 144 1.01E-8 T 23-10-2018 TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 SMART SM00490 253 334 6.4E-36 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 SUPERFAMILY SSF52540 70 355 5.77E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 Gene3D G3DSA:3.40.50.300 211 378 3.0E-55 T 23-10-2018 TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 SMART SM00487 20 218 1.1E-66 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 Gene3D G3DSA:3.40.50.300 1 207 3.5E-78 T 23-10-2018 TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 Pfam PF00271 Helicase conserved C-terminal domain 231 334 5.8E-31 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1041 95a92afc4445037dc00efda1a5a17b35 382 Pfam PF00270 DEAD/DEAH box helicase 25 189 3.0E-48 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 SUPERFAMILY SSF109604 31 119 3.93E-9 T 23-10-2018 TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 233 577 2.6E-69 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 SUPERFAMILY SSF52540 225 540 1.77E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 SMART SM00487 210 415 5.4E-6 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 SMART SM00490 456 540 4.9E-4 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 Gene3D G3DSA:3.40.50.300 410 561 1.1E-11 T 23-10-2018 TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 Gene3D G3DSA:3.40.50.300 205 409 1.8E-13 T 23-10-2018 TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 Pfam PF00270 DEAD/DEAH box helicase 224 395 2.2E-9 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 Pfam PF00271 Helicase conserved C-terminal domain 432 539 1.4E-6 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_1490 51f471ef1e490947f52a69eddbb02f1f 733 Gene3D G3DSA:1.10.3210.30 17 191 3.7E-10 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TSIB_1236 c688e7ba2ce7a039af9a8a1deef50e00 232 Pfam PF00881 Nitroreductase family 58 231 4.3E-32 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_1236 c688e7ba2ce7a039af9a8a1deef50e00 232 SUPERFAMILY SSF55469 52 231 3.66E-34 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1236 c688e7ba2ce7a039af9a8a1deef50e00 232 Gene3D G3DSA:3.40.109.10 24 231 3.3E-71 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1236 c688e7ba2ce7a039af9a8a1deef50e00 232 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 73 230 1.8E-44 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain TSIB_1355 02db572c40d9387712b2f0698c5f79c9 55 Gene3D G3DSA:3.40.50.10880 10 52 3.3E-5 T 23-10-2018 TSIB_1355 02db572c40d9387712b2f0698c5f79c9 55 SUPERFAMILY SSF111321 19 48 9.55E-5 T 23-10-2018 IPR036075 AF1104-like superfamily TSIB_1644 a28a979030a545a9907911bdb9cea7fb 261 Gene3D G3DSA:3.30.930.10 3 248 5.8E-57 T 23-10-2018 TSIB_1644 a28a979030a545a9907911bdb9cea7fb 261 SUPERFAMILY SSF55681 2 242 2.61E-58 T 23-10-2018 TSIB_1644 a28a979030a545a9907911bdb9cea7fb 261 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 160 1.4E-9 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 SUPERFAMILY SSF88697 254 337 3.37E-23 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 45 330 51.571 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 186 252 1.8E-24 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Pfam PF08068 DKCLD (NUC011) domain 16 68 1.1E-18 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 SUPERFAMILY SSF55120 27 252 5.47E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 SMART SM00359 256 330 5.6E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 24 339 6.0E-140 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Pfam PF01472 PUA domain 256 328 6.9E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Gene3D G3DSA:2.30.130.70 28 337 6.8E-149 T 23-10-2018 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Gene3D G3DSA:3.30.2350.10 45 248 6.8E-149 T 23-10-2018 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 SMART SM01136 9 68 4.6E-24 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 245 325 1.2E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 72 124 3.6E-16 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TSIB_0337 3b911b123a567f08ff5779a460be0d03 339 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 125 185 3.6E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 Pfam PF00005 ABC transporter 20 167 2.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 SUPERFAMILY SSF50331 242 371 2.67E-27 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 Gene3D G3DSA:2.40.50.100 245 304 6.4E-26 T 23-10-2018 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 Pfam PF08402 TOBE domain 288 363 1.9E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 SMART SM00382 28 217 1.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 Gene3D G3DSA:3.40.50.300 2 243 2.1E-75 T 23-10-2018 TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 SUPERFAMILY SSF52540 5 248 2.75E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0363 718bec5c76eee6ceed50602ae4098ba5 372 Gene3D G3DSA:2.40.50.140 310 354 1.8E-18 T 23-10-2018 TSIB_0355 cd69ef81c9b4a40afe14e36c2ad881e6 273 Gene3D G3DSA:3.40.50.1100 19 120 1.6E-67 T 23-10-2018 TSIB_0355 cd69ef81c9b4a40afe14e36c2ad881e6 273 SUPERFAMILY SSF53686 3 269 4.19E-60 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_0355 cd69ef81c9b4a40afe14e36c2ad881e6 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 254 8.7E-41 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_0355 cd69ef81c9b4a40afe14e36c2ad881e6 273 Gene3D G3DSA:3.40.50.1100 3 262 1.6E-67 T 23-10-2018 TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 Gene3D G3DSA:3.40.50.300 278 455 1.2E-34 T 23-10-2018 TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 Gene3D G3DSA:3.40.50.300 88 265 6.4E-34 T 23-10-2018 TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 SMART SM00487 95 266 7.7E-25 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 Pfam PF04851 Type III restriction enzyme, res subunit 96 235 5.4E-17 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 SUPERFAMILY SSF52540 32 218 2.21E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 SMART SM00490 332 410 4.0E-12 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 Pfam PF00271 Helicase conserved C-terminal domain 305 408 2.5E-12 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0619 a6186cad24966a17d8dd5641e9f593a2 456 SUPERFAMILY SSF52540 140 426 1.94E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0600 6c92edb95d82e45547f185cc3dac0dfc 182 Gene3D G3DSA:1.20.1260.10 19 174 2.3E-27 T 23-10-2018 IPR012347 Ferritin-like TSIB_0600 6c92edb95d82e45547f185cc3dac0dfc 182 Pfam PF02915 Rubrerythrin 37 170 4.5E-14 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_0600 6c92edb95d82e45547f185cc3dac0dfc 182 SUPERFAMILY SSF47240 27 175 4.62E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_0200 fec5ddd5b3e1d4480481dbc1a7b3f2eb 135 Gene3D G3DSA:2.60.120.460 1 135 1.8E-47 T 23-10-2018 IPR035917 YjbQ-like superfamily TSIB_0200 fec5ddd5b3e1d4480481dbc1a7b3f2eb 135 PIRSF PIRSF004681 1 135 1.9E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_0200 fec5ddd5b3e1d4480481dbc1a7b3f2eb 135 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 135 1.4E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_0200 fec5ddd5b3e1d4480481dbc1a7b3f2eb 135 SUPERFAMILY SSF111038 3 135 1.96E-42 T 23-10-2018 IPR035917 YjbQ-like superfamily TSIB_0200 fec5ddd5b3e1d4480481dbc1a7b3f2eb 135 Pfam PF01894 Uncharacterised protein family UPF0047 18 132 4.6E-35 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSIB_1877 6221c3e5bbb2f40e0e4178a2067ef5fc 278 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 12 270 2.4E-65 T 23-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TSIB_1877 6221c3e5bbb2f40e0e4178a2067ef5fc 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 268 5.8E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1877 6221c3e5bbb2f40e0e4178a2067ef5fc 278 Gene3D G3DSA:1.10.3720.10 3 268 1.8E-26 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1877 6221c3e5bbb2f40e0e4178a2067ef5fc 278 SUPERFAMILY SSF161098 21 266 2.15E-35 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 Gene3D G3DSA:3.40.50.300 3 246 5.0E-75 T 23-10-2018 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 Pfam PF00005 ABC transporter 25 169 6.5E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 SUPERFAMILY SSF54631 251 359 9.98E-9 T 23-10-2018 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 SUPERFAMILY SSF52540 9 244 1.91E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 SMART SM00382 33 227 1.4E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 18 357 7.2E-109 T 23-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 Gene3D G3DSA:3.10.580.10 254 363 4.3E-6 T 23-10-2018 TSIB_1889 b5a114d738c24f3fce255b82f33932bc 364 Pfam PF00571 CBS domain 316 362 1.9E-4 T 23-10-2018 IPR000644 CBS domain TSIB_1029 1e636b88e51a44e2c13b8ae8191a5dc4 304 Gene3D G3DSA:3.60.15.10 7 273 3.9E-11 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1029 1e636b88e51a44e2c13b8ae8191a5dc4 304 PIRSF PIRSF004944 1 301 2.5E-116 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TSIB_1029 1e636b88e51a44e2c13b8ae8191a5dc4 304 Hamap MF_01406 UPF0282 protein . 1 287 37.711 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TSIB_1029 1e636b88e51a44e2c13b8ae8191a5dc4 304 SUPERFAMILY SSF56281 1 262 2.26E-13 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 SUPERFAMILY SSF52374 2 363 2.71E-67 T 23-10-2018 TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 Gene3D G3DSA:3.40.50.620 1 226 2.9E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 48.416 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 Gene3D G3DSA:1.10.240.10 227 375 1.2E-56 T 23-10-2018 TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 352 6.2E-43 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0224 cae7c93ffe0a6396774e0568e2fd8fde 375 PIRSF PIRSF006588 1 375 7.9E-131 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 PIRSF PIRSF000915 16 279 4.2E-70 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 Gene3D G3DSA:3.40.50.1000 23 267 4.1E-95 T 23-10-2018 IPR023214 HAD superfamily TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 Gene3D G3DSA:3.40.50.1000 87 202 4.1E-95 T 23-10-2018 IPR023214 HAD superfamily TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 Pfam PF13242 HAD-hyrolase-like 202 273 1.7E-19 T 23-10-2018 TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 SUPERFAMILY SSF56784 21 274 1.47E-66 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 Pfam PF13344 Haloacid dehalogenase-like hydrolase 22 120 4.0E-31 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TSIB_0023 1df30a70ee7e0a197faa023627201d73 283 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 22 249 3.1E-47 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TSIB_0563 f4510967802346c10b5860316cb095a4 108 SMART SM00440 67 106 9.4E-25 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TSIB_0563 f4510967802346c10b5860316cb095a4 108 SMART SM00661 2 55 6.8E-17 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TSIB_0563 f4510967802346c10b5860316cb095a4 108 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site TSIB_0563 f4510967802346c10b5860316cb095a4 108 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 69 104 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TSIB_0563 f4510967802346c10b5860316cb095a4 108 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 108 7.8E-38 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 TSIB_0563 f4510967802346c10b5860316cb095a4 108 SUPERFAMILY SSF57783 1 32 1.87E-5 T 23-10-2018 TSIB_0563 f4510967802346c10b5860316cb095a4 108 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 32 9.5E-13 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TSIB_0563 f4510967802346c10b5860316cb095a4 108 PIRSF PIRSF005586 1 108 3.6E-39 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 TSIB_0563 f4510967802346c10b5860316cb095a4 108 SUPERFAMILY SSF57783 50 107 3.51E-23 T 23-10-2018 TSIB_0563 f4510967802346c10b5860316cb095a4 108 Gene3D G3DSA:2.20.25.10 53 108 1.8E-27 T 23-10-2018 TSIB_0563 f4510967802346c10b5860316cb095a4 108 Pfam PF01096 Transcription factor S-II (TFIIS) 67 105 1.2E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 166 360 1.0E-52 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 366 109.596 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 SUPERFAMILY SSF143437 3 164 5.23E-40 T 23-10-2018 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 Gene3D G3DSA:3.30.2130.30 1 165 7.0E-44 T 23-10-2018 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 Gene3D G3DSA:3.40.50.620 166 365 1.5E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 361 2.5E-97 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 SMART SM00981 70 156 5.3E-17 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 Pfam PF02926 THUMP domain 29 155 4.3E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1723 a02f54db87362bba0a3e8b03e40be9e0 366 SUPERFAMILY SSF52402 165 357 2.87E-43 T 23-10-2018 TSIB_1154 80b871e5f1b92879156a191a9b0788b6 171 SMART SM00981 70 160 3.3E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1154 80b871e5f1b92879156a191a9b0788b6 171 SUPERFAMILY SSF143437 36 159 1.52E-17 T 23-10-2018 TSIB_1154 80b871e5f1b92879156a191a9b0788b6 171 Pfam PF02926 THUMP domain 33 159 4.9E-17 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_1154 80b871e5f1b92879156a191a9b0788b6 171 Gene3D G3DSA:3.30.2130.30 8 161 3.2E-14 T 23-10-2018 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 Gene3D G3DSA:3.20.20.70 1 223 9.2E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 Pfam PF00121 Triosephosphate isomerase 6 109 1.4E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 210 1.4E-62 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 ProSitePatterns PS00171 Triosephosphate isomerase active site. 140 150 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 SUPERFAMILY SSF51351 2 219 2.88E-46 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 Pfam PF05690 Thiazole biosynthesis protein ThiG 166 214 4.3E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TSIB_1685 9941e61fce8ba3dddbc737f4b0e83fdb 224 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 4 223 43.713 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 TSIB_0203 a7e85fb0941286ace697c03b73bd0d5d 349 Hamap MF_01406 UPF0282 protein . 3 349 35.246 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TSIB_0203 a7e85fb0941286ace697c03b73bd0d5d 349 PIRSF PIRSF004944 3 139 1.2E-25 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TSIB_0203 a7e85fb0941286ace697c03b73bd0d5d 349 PIRSF PIRSF004944 144 349 1.9E-42 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TSIB_0203 a7e85fb0941286ace697c03b73bd0d5d 349 SUPERFAMILY SSF56281 11 332 1.65E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0203 a7e85fb0941286ace697c03b73bd0d5d 349 Pfam PF00753 Metallo-beta-lactamase superfamily 17 81 2.2E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1995 cebf1a0c790ff79c2fad9e155f7aad4d 335 SUPERFAMILY SSF88723 111 250 2.75E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_1995 cebf1a0c790ff79c2fad9e155f7aad4d 335 Pfam PF13638 PIN domain 112 248 5.0E-7 T 23-10-2018 IPR002716 PIN domain TSIB_1995 cebf1a0c790ff79c2fad9e155f7aad4d 335 Gene3D G3DSA:3.40.50.1010 104 253 7.1E-6 T 23-10-2018 TSIB_0693 a170bcd4b811f7cd945547e629acd293 142 Pfam PF04016 Putative heavy-metal chelation 18 137 5.8E-32 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain TSIB_0693 a170bcd4b811f7cd945547e629acd293 142 SUPERFAMILY SSF159713 5 138 1.44E-36 T 23-10-2018 TSIB_0693 a170bcd4b811f7cd945547e629acd293 142 Gene3D G3DSA:3.40.50.11590 11 129 5.7E-20 T 23-10-2018 TSIB_1896 4dda497fc9fbd5717dc11f024660a784 171 SUPERFAMILY SSF57802 137 170 1.36E-10 T 23-10-2018 TSIB_1896 4dda497fc9fbd5717dc11f024660a784 171 SUPERFAMILY SSF47240 5 130 4.28E-37 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1896 4dda497fc9fbd5717dc11f024660a784 171 Gene3D G3DSA:2.20.28.10 133 171 2.5E-19 T 23-10-2018 TSIB_1896 4dda497fc9fbd5717dc11f024660a784 171 Gene3D G3DSA:1.20.1260.10 2 132 7.8E-45 T 23-10-2018 IPR012347 Ferritin-like TSIB_1896 4dda497fc9fbd5717dc11f024660a784 171 Pfam PF02915 Rubrerythrin 10 124 3.1E-25 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1687 1c2107b0ab5e5860ccf1d0bbaeab7495 374 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 6.7E-186 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSIB_1687 1c2107b0ab5e5860ccf1d0bbaeab7495 374 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSIB_1687 1c2107b0ab5e5860ccf1d0bbaeab7495 374 PIRSF PIRSF015647 5 374 2.3E-190 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSIB_1687 1c2107b0ab5e5860ccf1d0bbaeab7495 374 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 60.883 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSIB_1687 1c2107b0ab5e5860ccf1d0bbaeab7495 374 SUPERFAMILY SSF111249 6 372 5.23E-175 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSIB_1486 f5736007e9f83e491429d9f93c6b4d0d 213 PIRSF PIRSF005054 3 205 6.1E-58 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1486 f5736007e9f83e491429d9f93c6b4d0d 213 Gene3D G3DSA:3.30.70.1900 85 203 1.3E-39 T 23-10-2018 TSIB_1486 f5736007e9f83e491429d9f93c6b4d0d 213 Pfam PF01881 CRISPR associated protein Cas6 57 201 4.7E-36 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1486 f5736007e9f83e491429d9f93c6b4d0d 213 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 5 200 7.5E-45 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TSIB_1486 f5736007e9f83e491429d9f93c6b4d0d 213 Gene3D G3DSA:3.30.70.1890 1 84 4.8E-24 T 23-10-2018 TSIB_1208 2b4ad1aea9149080b962c05c3f3094da 92 Gene3D G3DSA:3.40.50.150 11 80 2.6E-19 T 23-10-2018 TSIB_1208 2b4ad1aea9149080b962c05c3f3094da 92 SUPERFAMILY SSF53335 14 80 5.28E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1208 2b4ad1aea9149080b962c05c3f3094da 92 Pfam PF13649 Methyltransferase domain 42 80 8.4E-10 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 Gene3D G3DSA:3.40.50.880 1 187 1.1E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 SUPERFAMILY SSF52317 1 185 3.74E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.3E-9 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.3E-9 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.3E-9 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 3.4E-5 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 3.4E-5 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 1.2E-80 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 8.0E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.413 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 4.0E-12 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.0E-12 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 4.0E-12 T 23-10-2018 TSIB_0044 e9b15b1a0b54fcc40b916ec56d74bf8e 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 4.0E-12 T 23-10-2018 TSIB_0085 eec45e6cc9576ff90d263a48be145272 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 5 222 4.3E-82 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 TSIB_0085 eec45e6cc9576ff90d263a48be145272 224 Pfam PF04172 LrgB-like family 9 221 2.0E-74 T 23-10-2018 IPR007300 CidB/LrgB family TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 SUPERFAMILY SSF161098 288 537 1.87E-52 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 Gene3D G3DSA:1.10.3720.10 8 263 1.4E-62 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 SUPERFAMILY SSF161098 6 258 1.59E-54 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 256 2.6E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 362 534 3.6E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0367 0a2ea3994efa08199f26291820960bc0 543 Gene3D G3DSA:1.10.3720.10 286 541 6.3E-54 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0402 1418447c0f4ee2910b0c26c3cd8e04cd 232 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 219 3.6E-42 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_0402 1418447c0f4ee2910b0c26c3cd8e04cd 232 Gene3D G3DSA:3.40.50.11570 5 224 8.9E-50 T 23-10-2018 TSIB_1858 211b9b8a24a0a899d3f9477bbe0a8bc2 165 Gene3D G3DSA:3.40.1520.10 4 165 8.9E-73 T 23-10-2018 IPR036902 Ta1353-like superfamily TSIB_1858 211b9b8a24a0a899d3f9477bbe0a8bc2 165 Pfam PF04008 Adenosine specific kinase 10 162 9.3E-62 T 23-10-2018 IPR007153 Adenosine specific kinase TSIB_1858 211b9b8a24a0a899d3f9477bbe0a8bc2 165 SUPERFAMILY SSF103165 5 163 1.96E-59 T 23-10-2018 IPR036902 Ta1353-like superfamily TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 Gene3D G3DSA:3.50.50.60 86 452 4.1E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 Pfam PF04324 BFD-like [2Fe-2S] binding domain 502 554 1.9E-15 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 Pfam PF01266 FAD dependent oxidoreductase 86 456 6.2E-65 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 Gene3D G3DSA:1.10.10.1100 489 563 5.0E-24 T 23-10-2018 TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 SUPERFAMILY SSF54373 320 415 1.16E-5 T 23-10-2018 TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 SUPERFAMILY SSF51905 84 465 5.5E-49 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0771 f3c3159f0b963bc1e3fb73f84d3eef1f 579 Gene3D G3DSA:3.30.9.10 169 418 4.1E-111 T 23-10-2018 TSIB_1161 3e58a7a6fd042c0e5a25173ef94194cc 195 Hamap MF_00582 UPF0215 protein . 9 189 33.924 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TSIB_1161 3e58a7a6fd042c0e5a25173ef94194cc 195 PIRSF PIRSF006380 1 195 5.5E-72 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TSIB_1161 3e58a7a6fd042c0e5a25173ef94194cc 195 Gene3D G3DSA:3.30.2170.10 3 195 1.1E-61 T 23-10-2018 TSIB_1161 3e58a7a6fd042c0e5a25173ef94194cc 195 Pfam PF01949 Protein of unknown function DUF99 8 188 7.5E-65 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TSIB_1161 3e58a7a6fd042c0e5a25173ef94194cc 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 191 4.0E-44 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TSIB_1182 a351043e5c94e40c2f124f52abc0aa51 311 ProSitePatterns PS00869 Renal dipeptidase active site. 99 121 - T 23-10-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TSIB_1182 a351043e5c94e40c2f124f52abc0aa51 311 Gene3D G3DSA:3.20.20.140 1 310 5.5E-92 T 23-10-2018 TSIB_1182 a351043e5c94e40c2f124f52abc0aa51 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 2.4E-93 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TSIB_1182 a351043e5c94e40c2f124f52abc0aa51 311 SUPERFAMILY SSF51556 1 310 9.93E-74 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_0587 3d3f31f2d36cefe0e39384017359d9f4 221 Gene3D G3DSA:1.10.10.10 156 217 3.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0587 3d3f31f2d36cefe0e39384017359d9f4 221 Pfam PF04967 HTH DNA binding domain 165 217 3.2E-22 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain TSIB_0587 3d3f31f2d36cefe0e39384017359d9f4 221 SUPERFAMILY SSF88659 161 217 4.58E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 Gene3D G3DSA:3.40.50.150 143 466 1.9E-74 T 23-10-2018 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 271 283 4.8E-21 T 23-10-2018 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 169 185 4.8E-21 T 23-10-2018 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 207 4.8E-21 T 23-10-2018 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 322 4.8E-21 T 23-10-2018 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 274 280 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 Gene3D G3DSA:1.20.1260.30 1 142 5.1E-32 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 Pfam PF12161 HsdM N-terminal domain 6 130 6.2E-11 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 SUPERFAMILY SSF53335 4 496 1.18E-109 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1611 4e154c3817ab5b2969e42eaab5e8a857 498 Pfam PF02384 N-6 DNA Methylase 146 458 3.5E-64 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TSIB_0992 8c99225468c5f5ddb10a3323d6b01286 415 SUPERFAMILY SSF51338 13 407 2.25E-24 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_0992 8c99225468c5f5ddb10a3323d6b01286 415 Gene3D G3DSA:3.20.20.140 56 342 2.9E-117 T 23-10-2018 TSIB_0992 8c99225468c5f5ddb10a3323d6b01286 415 Pfam PF01979 Amidohydrolase family 53 395 1.8E-55 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSIB_0992 8c99225468c5f5ddb10a3323d6b01286 415 SUPERFAMILY SSF51556 55 345 5.11E-79 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_0992 8c99225468c5f5ddb10a3323d6b01286 415 Gene3D G3DSA:2.30.40.10 8 407 2.9E-117 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_1959 ba5d02f6c1913e4cb24ac3bcb8cd1e64 473 Pfam PF04415 Protein of unknown function (DUF515) 43 471 3.9E-132 T 23-10-2018 IPR007509 Protein of unknown function DUF515 TSIB_0871 6edb172d1fac1255fa7f3673358629e0 153 SUPERFAMILY SSF47113 1 153 8.15E-48 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_0871 6edb172d1fac1255fa7f3673358629e0 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 1.6E-43 T 23-10-2018 IPR015207 Protein of unknown function DUF1931 TSIB_0871 6edb172d1fac1255fa7f3673358629e0 153 Gene3D G3DSA:1.10.20.10 4 153 3.0E-33 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1278 e16b92368d5ba6bb252a5f6b12ebe09c 121 Gene3D G3DSA:1.10.10.10 19 86 3.5E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1278 e16b92368d5ba6bb252a5f6b12ebe09c 121 Pfam PF03965 Penicillinase repressor 19 116 3.6E-18 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 TSIB_1278 e16b92368d5ba6bb252a5f6b12ebe09c 121 SUPERFAMILY SSF46785 17 118 6.48E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0325 826337085fcd3ad0f3e826254347587f 491 SUPERFAMILY SSF51445 91 466 7.6E-29 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TSIB_0325 826337085fcd3ad0f3e826254347587f 491 Gene3D G3DSA:3.20.20.80 29 482 2.5E-126 T 23-10-2018 TSIB_1909 4791f22f1667539f1b973bb414e0e334 309 Pfam PF00146 NADH dehydrogenase 8 306 6.3E-51 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 Gene3D G3DSA:3.40.50.300 10 335 9.7E-102 T 23-10-2018 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 313 2.0E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 Pfam PF00005 ABC transporter 44 196 9.2E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 SMART SM00382 52 246 2.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 332 5.4E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1056 8c8946bd8d0ff5f78318e1adfb1e0b30 336 SUPERFAMILY SSF52540 12 267 1.77E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1284 8bca01e528a277f11af32692c052865c 412 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 44 69 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSIB_1284 8bca01e528a277f11af32692c052865c 412 SUPERFAMILY SSF56762 15 376 1.28E-102 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1284 8bca01e528a277f11af32692c052865c 412 Pfam PF00374 Nickel-dependent hydrogenase 44 112 9.7E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_1284 8bca01e528a277f11af32692c052865c 412 Gene3D G3DSA:1.10.645.20 7 376 5.1E-117 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1284 8bca01e528a277f11af32692c052865c 412 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 376 3.6E-61 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0925 83a5010f03168778ffdb62009e49cc12 192 Gene3D G3DSA:3.10.105.10 84 150 3.7E-7 T 23-10-2018 TSIB_0925 83a5010f03168778ffdb62009e49cc12 192 SUPERFAMILY SSF53850 94 175 4.34E-8 T 23-10-2018 TSIB_0925 83a5010f03168778ffdb62009e49cc12 192 Gene3D G3DSA:3.40.190.10 151 164 3.7E-7 T 23-10-2018 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 3.2E-15 T 23-10-2018 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 SUPERFAMILY SSF46785 4 84 2.43E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 Gene3D G3DSA:3.30.70.920 57 160 2.9E-43 T 23-10-2018 TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 Gene3D G3DSA:1.10.10.10 1 56 6.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0507 50ab6be2538dc6e4038310c6da58962f 160 SMART SM00344 4 116 2.6E-8 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1835 1e8b844ec49c1969085fafed3e1a077e 428 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 79 3.8E-11 T 23-10-2018 TSIB_1835 1e8b844ec49c1969085fafed3e1a077e 428 Gene3D G3DSA:3.50.50.60 13 411 2.2E-136 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1835 1e8b844ec49c1969085fafed3e1a077e 428 Gene3D G3DSA:3.90.660.50 92 368 2.2E-136 T 23-10-2018 TSIB_1835 1e8b844ec49c1969085fafed3e1a077e 428 SUPERFAMILY SSF51905 10 396 3.45E-35 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0326 eb6f6f0a4c92f42ac62e70b4a84ba1ac 378 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 358 377 1.3E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TSIB_0326 eb6f6f0a4c92f42ac62e70b4a84ba1ac 378 Gene3D G3DSA:2.60.120.180 44 308 1.2E-39 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 Gene3D G3DSA:3.80.30.20 162 387 8.1E-40 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 Gene3D G3DSA:3.40.50.280 2 127 8.3E-28 T 23-10-2018 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 Pfam PF02310 B12 binding domain 21 108 2.1E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 Pfam PF04055 Radical SAM superfamily 168 339 1.3E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 SUPERFAMILY SSF102114 161 378 6.54E-40 T 23-10-2018 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 SMART SM00729 164 382 4.4E-50 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1482 de2ace8d03b21a5d346211023cea5e7e 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 2.5E-140 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type TSIB_0496 1f4574ba2660f4bb51e16e1249cf03eb 268 Gene3D G3DSA:3.20.20.150 16 258 3.6E-29 T 23-10-2018 TSIB_0496 1f4574ba2660f4bb51e16e1249cf03eb 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 1.1E-17 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSIB_0496 1f4574ba2660f4bb51e16e1249cf03eb 268 SUPERFAMILY SSF51658 1 241 3.14E-29 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 SMART SM01192 124 340 2.4E-13 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 PRINTS PR00148 Enolase signature 92 108 2.0E-6 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 PRINTS PR00148 Enolase signature 316 330 2.0E-6 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 SMART SM01193 4 119 6.2E-27 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 Pfam PF03952 Enolase, N-terminal domain 39 119 3.2E-22 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 SUPERFAMILY SSF54826 4 125 2.36E-28 T 23-10-2018 TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 Gene3D G3DSA:3.30.390.10 1 111 4.9E-19 T 23-10-2018 IPR029017 Enolase-like, N-terminal TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 Gene3D G3DSA:3.20.20.120 195 339 2.1E-12 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSIB_0348 69ca4c5f4cf9b9e62203cf563f635f79 341 SUPERFAMILY SSF51604 113 337 1.1E-28 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 1.4E-32 T 23-10-2018 TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 SUPERFAMILY SSF56784 1 224 1.47E-48 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 Gene3D G3DSA:3.40.50.1000 4 220 7.6E-88 T 23-10-2018 IPR023214 HAD superfamily TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 188 1.9E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 89 195 4.9E-15 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 193 7.5E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 220 4.2E-88 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TSIB_0625 6799e2e5702d68a1cfedae856918e95f 239 Gene3D G3DSA:1.10.150.520 16 94 7.6E-88 T 23-10-2018 TSIB_1647 f96696eb0e57a66ba91e3823c9b0688f 335 Pfam PF00676 Dehydrogenase E1 component 48 324 2.0E-85 T 23-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSIB_1647 f96696eb0e57a66ba91e3823c9b0688f 335 Gene3D G3DSA:3.40.50.970 1 335 6.6E-121 T 23-10-2018 TSIB_1647 f96696eb0e57a66ba91e3823c9b0688f 335 SUPERFAMILY SSF52518 5 333 1.73E-100 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1801 fb265ca7fc2085edc610f1bfcf39c5b5 286 Gene3D G3DSA:1.20.1640.10 96 286 3.8E-11 T 23-10-2018 TSIB_1801 fb265ca7fc2085edc610f1bfcf39c5b5 286 Pfam PF02355 Protein export membrane protein 108 281 2.3E-29 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TSIB_1801 fb265ca7fc2085edc610f1bfcf39c5b5 286 SUPERFAMILY SSF82866 108 278 7.59E-22 T 23-10-2018 TSIB_1801 fb265ca7fc2085edc610f1bfcf39c5b5 286 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 13 285 26.057 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 TSIB_1238 62290e4d5a22187a397547e9736cc465 122 Gene3D G3DSA:2.60.120.10 1 119 8.5E-37 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_1238 62290e4d5a22187a397547e9736cc465 122 Pfam PF07883 Cupin domain 41 108 2.1E-16 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_1238 62290e4d5a22187a397547e9736cc465 122 SUPERFAMILY SSF51182 13 109 1.08E-25 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_0475 6cc36ba7da169a6c55ed1ea1b0c33b60 350 Pfam PF13353 4Fe-4S single cluster domain 135 222 2.1E-8 T 23-10-2018 TSIB_0475 6cc36ba7da169a6c55ed1ea1b0c33b60 350 PIRSF PIRSF004869 39 350 2.4E-66 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TSIB_0475 6cc36ba7da169a6c55ed1ea1b0c33b60 350 Pfam PF04055 Radical SAM superfamily 137 284 8.6E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0475 6cc36ba7da169a6c55ed1ea1b0c33b60 350 SUPERFAMILY SSF102114 139 338 2.49E-20 T 23-10-2018 TSIB_0475 6cc36ba7da169a6c55ed1ea1b0c33b60 350 Gene3D G3DSA:3.20.20.70 130 347 2.2E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 Gene3D G3DSA:3.40.50.11030 216 341 1.4E-38 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 Gene3D G3DSA:3.90.870.10 2 213 3.3E-86 T 23-10-2018 TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 335 3.8E-28 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 208 3.4E-69 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 SUPERFAMILY SSF55821 11 210 9.77E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 Pfam PF01300 Telomere recombination 22 197 1.7E-60 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TSIB_1410 1e580b799efe8ebb75a5dd8062d9f9b4 341 PIRSF PIRSF004930 1 341 2.7E-136 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 TSIB_0750 80f2c8db55d2991a0185735b5319ae99 157 Gene3D G3DSA:3.30.479.10 11 155 1.6E-34 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TSIB_0750 80f2c8db55d2991a0185735b5319ae99 157 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 15 154 7.3E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TSIB_0750 80f2c8db55d2991a0185735b5319ae99 157 SUPERFAMILY SSF55620 15 155 3.95E-36 T 23-10-2018 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 Gene3D G3DSA:2.170.16.10 949 1114 3.0E-56 T 23-10-2018 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 SUPERFAMILY SSF51294 949 1115 2.35E-31 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 SMART SM00306 947 1069 2.8E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 SMART SM00305 1070 1120 2.8E-4 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 Pfam PF03833 DNA polymerase II large subunit DP2 10 948 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1381 456.731 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 6 963 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 Pfam PF14890 Intein splicing domain 993 1075 2.0E-11 T 23-10-2018 TSIB_1588 d7e82134c35f7ec969ab5470aefcaded 1442 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 949 1045 1.3E-14 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 2.1E-62 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 SUPERFAMILY SSF51569 2 291 2.2E-78 T 23-10-2018 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 PIRSF PIRSF001365 1 293 2.0E-79 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 1.5E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 1.5E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 1.5E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 1.5E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 Gene3D G3DSA:3.20.20.70 1 294 9.0E-90 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 SMART SM01130 1 292 6.0E-92 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1926 fce9dec8804ef87c309b4a29d9fc06d7 295 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 SUPERFAMILY SSF52743 127 986 4.54E-39 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Gene3D G3DSA:3.40.50.200 667 966 2.3E-42 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Pfam PF00082 Subtilase family 246 948 2.9E-28 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 PRINTS PR00723 Subtilisin serine protease family (S8) signature 246 265 2.7E-12 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 PRINTS PR00723 Subtilisin serine protease family (S8) signature 894 910 2.7E-12 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Gene3D G3DSA:3.40.50.200 219 294 6.0E-7 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 1407 1480 9.6E-7 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Gene3D G3DSA:2.60.120.380 1395 1499 2.1E-12 T 23-10-2018 TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 Pfam PF07705 CARDB 1573 1643 5.1E-6 T 23-10-2018 IPR011635 CARDB domain TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 895 905 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TSIB_0267 eeb7cd37c6f8005d25ea92a960b34eed 1870 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 251 262 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TSIB_2026 b1232a4dab62b283b01a93e18e277e0f 324 Pfam PF00535 Glycosyl transferase family 2 7 114 5.8E-25 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_2026 b1232a4dab62b283b01a93e18e277e0f 324 Gene3D G3DSA:3.90.550.10 1 222 2.7E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2026 b1232a4dab62b283b01a93e18e277e0f 324 SUPERFAMILY SSF53448 2 278 8.04E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2026 b1232a4dab62b283b01a93e18e277e0f 324 Pfam PF13632 Glycosyl transferase family group 2 169 279 5.8E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_0285 0498f11e12a115529d21ee3af639e3d4 427 SUPERFAMILY SSF56762 5 423 2.35E-94 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0285 0498f11e12a115529d21ee3af639e3d4 427 Pfam PF00374 Nickel-dependent hydrogenase 40 118 2.4E-11 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_0285 0498f11e12a115529d21ee3af639e3d4 427 Pfam PF00374 Nickel-dependent hydrogenase 319 423 1.6E-10 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_0285 0498f11e12a115529d21ee3af639e3d4 427 Gene3D G3DSA:1.10.645.10 1 423 7.5E-103 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0285 0498f11e12a115529d21ee3af639e3d4 427 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 414 423 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSIB_1864 8009ad7d0b649f318e8b5c546af4dd7f 344 Pfam PF01032 FecCD transport family 21 339 2.9E-97 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSIB_1864 8009ad7d0b649f318e8b5c546af4dd7f 344 Gene3D G3DSA:1.10.3470.10 8 343 8.5E-106 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TSIB_1864 8009ad7d0b649f318e8b5c546af4dd7f 344 SUPERFAMILY SSF81345 6 339 1.01E-85 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TSIB_1170 844041cac73c43af545c844343bf01bf 97 Gene3D G3DSA:1.10.10.10 5 93 2.5E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1170 844041cac73c43af545c844343bf01bf 97 SMART SM00418 10 89 2.5E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1170 844041cac73c43af545c844343bf01bf 97 SUPERFAMILY SSF46785 5 82 2.5E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1170 844041cac73c43af545c844343bf01bf 97 Pfam PF01022 Bacterial regulatory protein, arsR family 17 63 7.6E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 595 8.2E-240 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Gene3D G3DSA:2.40.30.10 228 337 7.0E-42 T 23-10-2018 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Pfam PF11987 Translation-initiation factor 2 350 446 5.3E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 6.5E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Gene3D G3DSA:3.40.50.300 1 227 5.9E-65 T 23-10-2018 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 1.4E-30 T 23-10-2018 IPR029459 Elongation factor Tu-type domain TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 SUPERFAMILY SSF52540 5 288 1.23E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 7.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 7.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 7.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 7.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 SUPERFAMILY SSF52156 334 460 2.48E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Gene3D G3DSA:2.40.30.10 466 556 6.7E-31 T 23-10-2018 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 157 3.5E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 SUPERFAMILY SSF50447 466 592 1.19E-25 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 5.5E-31 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 44.099 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TSIB_0532 642ae2ad542e0ac054e5e18f9b611fd5 597 Gene3D G3DSA:3.40.50.10050 349 457 6.2E-34 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSIB_0127 9803adc189e57130ae3ebe2339101bc4 108 Pfam PF01883 Iron-sulfur cluster assembly protein 12 85 6.0E-22 T 23-10-2018 IPR002744 MIP18 family-like TSIB_0127 9803adc189e57130ae3ebe2339101bc4 108 SUPERFAMILY SSF117916 9 107 5.56E-34 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_0127 9803adc189e57130ae3ebe2339101bc4 108 Gene3D G3DSA:3.30.300.130 4 107 3.5E-37 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSIB_0222 d10e587765c991300ddf980363e92783 489 Pfam PF13416 Bacterial extracellular solute-binding protein 117 361 3.2E-20 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSIB_0222 d10e587765c991300ddf980363e92783 489 SUPERFAMILY SSF53850 90 360 4.18E-40 T 23-10-2018 TSIB_0222 d10e587765c991300ddf980363e92783 489 Gene3D G3DSA:3.40.190.10 116 354 4.0E-30 T 23-10-2018 TSIB_0222 d10e587765c991300ddf980363e92783 489 Gene3D G3DSA:3.40.190.10 181 300 4.0E-30 T 23-10-2018 TSIB_1216 30f1cca18a7d3ec67052fec890446774 230 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 6 228 3.2E-55 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TSIB_1216 30f1cca18a7d3ec67052fec890446774 230 Pfam PF03749 Sugar fermentation stimulation protein 13 217 4.8E-49 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TSIB_1216 30f1cca18a7d3ec67052fec890446774 230 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 229 37.773 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TSIB_1216 30f1cca18a7d3ec67052fec890446774 230 Gene3D G3DSA:2.40.50.580 1 77 1.2E-23 T 23-10-2018 TSIB_1216 30f1cca18a7d3ec67052fec890446774 230 Gene3D G3DSA:3.40.1350.60 78 229 1.0E-43 T 23-10-2018 TSIB_1100 19d2f058643fab56632fc073fdd35617 265 Pfam PF02649 Type I GTP cyclohydrolase folE2 1 261 3.8E-66 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 TSIB_1100 19d2f058643fab56632fc073fdd35617 265 Gene3D G3DSA:3.10.270.10 1 264 9.2E-68 T 23-10-2018 TSIB_1634 ec6e006397baaa3c1b19e03fd5dff63d 476 Gene3D G3DSA:3.40.50.12030 188 436 5.5E-60 T 23-10-2018 TSIB_1634 ec6e006397baaa3c1b19e03fd5dff63d 476 Pfam PF06792 Uncharacterised protein family (UPF0261) 5 358 7.5E-90 T 23-10-2018 IPR008322 Uncharacterised protein family UPF0261 TSIB_1634 ec6e006397baaa3c1b19e03fd5dff63d 476 Gene3D G3DSA:3.40.50.12020 1 182 2.5E-38 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 Hamap MF_00384 Homoserine kinase [thrB]. 3 286 25.679 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PIRSF PIRSF000676 1 292 3.8E-73 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 Pfam PF00288 GHMP kinases N terminal domain 75 138 2.4E-11 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PRINTS PR00958 Homoserine kinase signature 8 23 7.1E-26 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PRINTS PR00958 Homoserine kinase signature 162 179 7.1E-26 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PRINTS PR00958 Homoserine kinase signature 126 139 7.1E-26 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PRINTS PR00958 Homoserine kinase signature 87 102 7.1E-26 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 PRINTS PR00958 Homoserine kinase signature 241 256 7.1E-26 T 23-10-2018 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 Pfam PF08544 GHMP kinases C terminal 198 270 1.2E-11 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 SUPERFAMILY SSF54211 1 153 6.68E-24 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 SUPERFAMILY SSF55060 157 271 7.91E-28 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 TIGRFAM TIGR00191 thrB: homoserine kinase 1 284 5.3E-56 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 Gene3D G3DSA:3.30.70.890 155 259 8.6E-72 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_1118 da12afb662076337d70bbe7de37d90c5 292 Gene3D G3DSA:3.30.230.10 2 154 8.6E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_0958 a41db4d2c5e8fbcdbeb8ba29f6771766 340 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 35 338 41.854 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 TSIB_0958 a41db4d2c5e8fbcdbeb8ba29f6771766 340 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 24 339 2.1E-123 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TSIB_0958 a41db4d2c5e8fbcdbeb8ba29f6771766 340 Gene3D G3DSA:3.40.910.10 5 340 7.5E-144 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TSIB_0958 a41db4d2c5e8fbcdbeb8ba29f6771766 340 Pfam PF01916 Deoxyhypusine synthase 38 335 6.1E-115 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TSIB_0958 a41db4d2c5e8fbcdbeb8ba29f6771766 340 SUPERFAMILY SSF52467 7 338 7.19E-116 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 Gene3D G3DSA:3.90.1070.10 82 151 4.8E-68 T 23-10-2018 TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 217 4.8E-73 T 23-10-2018 TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 SUPERFAMILY SSF56784 1 226 8.78E-42 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 230 2.2E-67 T 23-10-2018 TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 Gene3D G3DSA:3.40.50.1000 3 220 4.8E-68 T 23-10-2018 IPR023214 HAD superfamily TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 Hamap MF_01419 Phosphoglycolate phosphatase. 2 227 30.342 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 Pfam PF08282 haloacid dehalogenase-like hydrolase 137 217 6.7E-19 T 23-10-2018 TSIB_0439 6f0c84c4dd2643703156f995b5b4a88b 234 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 78 5.4E-9 T 23-10-2018 TSIB_0578 892480640e662991b191bca8b95c76a1 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 381 5.6E-123 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 TSIB_0578 892480640e662991b191bca8b95c76a1 421 SUPERFAMILY SSF89550 3 227 4.32E-13 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSIB_0578 892480640e662991b191bca8b95c76a1 421 Pfam PF13263 PHP-associated 176 225 2.5E-5 T 23-10-2018 TSIB_0578 892480640e662991b191bca8b95c76a1 421 Gene3D G3DSA:3.20.20.140 2 234 2.1E-13 T 23-10-2018 TSIB_0813 11dbb64e8a5e73c126f29b8b0b3c9485 190 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 26 183 1.4E-41 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TSIB_0813 11dbb64e8a5e73c126f29b8b0b3c9485 190 Gene3D G3DSA:2.60.120.10 1 190 6.7E-79 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0813 11dbb64e8a5e73c126f29b8b0b3c9485 190 PIRSF PIRSF019325 1 190 2.5E-81 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TSIB_0813 11dbb64e8a5e73c126f29b8b0b3c9485 190 SUPERFAMILY SSF51182 2 188 1.42E-46 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_0983 7ac519b294f63030f77e3bf2a90bdf16 289 SUPERFAMILY SSF103481 59 144 4.84E-14 T 23-10-2018 TSIB_0983 7ac519b294f63030f77e3bf2a90bdf16 289 SUPERFAMILY SSF103481 208 286 2.09E-10 T 23-10-2018 TSIB_0983 7ac519b294f63030f77e3bf2a90bdf16 289 Pfam PF00892 EamA-like transporter family 5 140 2.0E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_0983 7ac519b294f63030f77e3bf2a90bdf16 289 Pfam PF00892 EamA-like transporter family 152 287 8.6E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 Gene3D G3DSA:3.40.50.300 1 259 1.6E-70 T 23-10-2018 TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 Pfam PF00005 ABC transporter 17 162 2.3E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 193 5.1E-65 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 SMART SM00382 26 216 2.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 SUPERFAMILY SSF52540 2 225 3.51E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1320 ba587447cc3c05ff0f1ecec7c833b73f 262 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 SUPERFAMILY SSF53901 236 386 1.18E-28 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 Gene3D G3DSA:3.40.47.10 8 387 7.5E-120 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 PIRSF PIRSF000429 2 386 9.8E-64 T 23-10-2018 IPR002155 Thiolase GO:0016747 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 Pfam PF00108 Thiolase, N-terminal domain 8 225 4.7E-25 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 Pfam PF02803 Thiolase, C-terminal domain 259 358 1.4E-9 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSIB_0800 6b9ad19f982d3c22197eede95c1cfe9f 388 SUPERFAMILY SSF53901 8 229 3.26E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0888 63f28f73b184a9a9f84c38253e521360 154 Pfam PF01850 PIN domain 6 148 3.8E-26 T 23-10-2018 IPR002716 PIN domain TSIB_0888 63f28f73b184a9a9f84c38253e521360 154 SMART SM00670 4 144 3.7E-17 T 23-10-2018 IPR002716 PIN domain TSIB_0888 63f28f73b184a9a9f84c38253e521360 154 Gene3D G3DSA:3.40.50.1010 5 152 2.0E-16 T 23-10-2018 TSIB_0888 63f28f73b184a9a9f84c38253e521360 154 SUPERFAMILY SSF88723 5 147 2.13E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0888 63f28f73b184a9a9f84c38253e521360 154 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 152 10.19 T 23-10-2018 IPR022907 VapC family GO:0004540 TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 SMART SM00116 81 128 0.098 T 23-10-2018 IPR000644 CBS domain TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 SMART SM00116 16 63 1.8E-9 T 23-10-2018 IPR000644 CBS domain TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 Gene3D G3DSA:3.10.580.10 2 177 1.8E-38 T 23-10-2018 TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 SUPERFAMILY SSF54631 4 134 1.52E-29 T 23-10-2018 TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 Pfam PF00571 CBS domain 9 62 4.4E-11 T 23-10-2018 IPR000644 CBS domain TSIB_1201 3e648d5efa6ea2abee21282b7fcc2b77 180 Pfam PF00571 CBS domain 74 127 1.0E-8 T 23-10-2018 IPR000644 CBS domain TSIB_1668 068675ce5d6c097db52c98c8853e802f 275 PIRSF PIRSF036668 3 275 2.2E-124 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related TSIB_1668 068675ce5d6c097db52c98c8853e802f 275 Gene3D G3DSA:3.40.50.620 4 195 1.5E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1668 068675ce5d6c097db52c98c8853e802f 275 Pfam PF06508 Queuosine biosynthesis protein QueC 56 134 2.1E-9 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSIB_1668 068675ce5d6c097db52c98c8853e802f 275 SUPERFAMILY SSF52402 26 204 1.59E-29 T 23-10-2018 TSIB_1868 2730d9f4e6ce37786e39d783c596692f 506 SUPERFAMILY SSF53720 22 499 1.44E-124 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSIB_1868 2730d9f4e6ce37786e39d783c596692f 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSIB_1868 2730d9f4e6ce37786e39d783c596692f 506 Gene3D G3DSA:3.40.309.10 270 469 5.2E-128 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSIB_1868 2730d9f4e6ce37786e39d783c596692f 506 Pfam PF00171 Aldehyde dehydrogenase family 39 493 1.0E-118 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSIB_1868 2730d9f4e6ce37786e39d783c596692f 506 Gene3D G3DSA:3.40.605.10 39 269 5.2E-128 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSIB_1838 d63ef11ac99983240467fc4dfa1120c8 174 Pfam PF01613 Flavin reductase like domain 9 142 6.1E-23 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSIB_1838 d63ef11ac99983240467fc4dfa1120c8 174 SMART SM00903 7 150 1.9E-15 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSIB_1838 d63ef11ac99983240467fc4dfa1120c8 174 Gene3D G3DSA:2.30.110.10 3 173 1.1E-46 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSIB_1838 d63ef11ac99983240467fc4dfa1120c8 174 SUPERFAMILY SSF50475 4 166 2.45E-39 T 23-10-2018 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 2.5E-62 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 400 33.837 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 PIRSF PIRSF000724 1 407 2.0E-130 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 Pfam PF00162 Phosphoglycerate kinase 5 389 5.6E-109 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 SUPERFAMILY SSF53748 2 399 8.13E-117 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 Gene3D G3DSA:3.40.50.1260 189 390 8.1E-138 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0215 baaf27f71c1617c9ed861acb2b8ab1dc 413 Gene3D G3DSA:3.40.50.1260 9 397 8.1E-138 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 SUPERFAMILY SSF46785 4 63 5.0E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 6.5E-19 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 Gene3D G3DSA:1.10.60.10 69 124 4.4E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 SMART SM00529 25 125 1.5E-35 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 Gene3D G3DSA:1.10.10.10 3 68 7.3E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 4.9E-19 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TSIB_0121 d78dbaf86bb24c68100dc9a122ac3b52 141 SUPERFAMILY SSF47979 64 136 2.35E-16 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TSIB_2014 69bb3364ec5403a4abb0afa483f7a290 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 3.8E-56 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSIB_2014 69bb3364ec5403a4abb0afa483f7a290 317 Gene3D G3DSA:3.90.25.10 177 302 7.5E-96 T 23-10-2018 TSIB_2014 69bb3364ec5403a4abb0afa483f7a290 317 SUPERFAMILY SSF51735 1 314 2.15E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_2014 69bb3364ec5403a4abb0afa483f7a290 317 Gene3D G3DSA:3.40.50.720 3 241 7.5E-96 T 23-10-2018 TSIB_0596 4a65da67b25aad4c566bc25502027994 361 Pfam PF04055 Radical SAM superfamily 92 247 3.5E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0596 4a65da67b25aad4c566bc25502027994 361 Gene3D G3DSA:3.20.20.70 79 299 3.3E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0596 4a65da67b25aad4c566bc25502027994 361 SUPERFAMILY SSF102114 70 328 2.49E-35 T 23-10-2018 TSIB_0596 4a65da67b25aad4c566bc25502027994 361 PIRSF PIRSF004869 10 326 1.1E-99 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TSIB_0596 4a65da67b25aad4c566bc25502027994 361 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 18 354 1.0E-111 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TSIB_0596 4a65da67b25aad4c566bc25502027994 361 Pfam PF13353 4Fe-4S single cluster domain 86 178 1.8E-7 T 23-10-2018 TSIB_0596 4a65da67b25aad4c566bc25502027994 361 SMART SM00729 85 291 0.008 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0648 b2f057e3dbe104e353528074d22645cd 152 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 7 142 16.163 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TSIB_0648 b2f057e3dbe104e353528074d22645cd 152 SUPERFAMILY SSF46579 11 144 1.44E-31 T 23-10-2018 TSIB_0648 b2f057e3dbe104e353528074d22645cd 152 Gene3D G3DSA:1.10.287.370 2 151 5.9E-48 T 23-10-2018 IPR009053 Prefoldin TSIB_0648 b2f057e3dbe104e353528074d22645cd 152 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 12 142 1.5E-37 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TSIB_0648 b2f057e3dbe104e353528074d22645cd 152 Pfam PF02996 Prefoldin subunit 23 142 1.5E-29 T 23-10-2018 IPR004127 Prefoldin alpha-like TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 Pfam PF01992 ATP synthase (C/AC39) subunit 39 363 7.4E-68 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 SUPERFAMILY SSF103486 35 365 1.14E-73 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 Gene3D G3DSA:1.10.132.50 35 357 1.8E-56 T 23-10-2018 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 367 24.064 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 Gene3D G3DSA:1.20.1690.10 112 209 1.8E-56 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 365 1.1E-97 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TSIB_1794 257357ca729f26852f6e1b0aebe0d544 369 Gene3D G3DSA:1.20.1690.10 220 326 1.8E-56 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_0261 f4597b669b53999871f7d1883e6c95f0 402 Pfam PF01385 Probable transposase 139 264 3.4E-38 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_0261 f4597b669b53999871f7d1883e6c95f0 402 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 237 311 5.3E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_0261 f4597b669b53999871f7d1883e6c95f0 402 Pfam PF07282 Putative transposase DNA-binding domain 284 353 7.0E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Gene3D G3DSA:3.90.870.20 329 532 4.0E-76 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 SUPERFAMILY SSF53067 3 313 9.5E-14 T 23-10-2018 TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Gene3D G3DSA:3.30.420.40 10 311 3.4E-66 T 23-10-2018 TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Pfam PF02543 Carbamoyltransferase N-terminus 3 66 2.1E-8 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Pfam PF02543 Carbamoyltransferase N-terminus 86 310 2.0E-42 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Gene3D G3DSA:3.30.420.350 96 304 3.4E-66 T 23-10-2018 TSIB_0775 dd2638d635e014fba6d30259efa1bc5b 533 Pfam PF16861 Carbamoyltransferase C-terminus 366 531 2.5E-63 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 Pfam PF01280 Ribosomal protein L19e 2 142 7.3E-56 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 SMART SM01416 1 144 1.4E-80 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 Gene3D G3DSA:1.10.1650.10 1 54 5.0E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 Gene3D G3DSA:1.10.1200.240 56 147 9.0E-29 T 23-10-2018 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 25.355 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0307 7dd2111aa7923e57c910eeb5d1c5f5a3 148 SUPERFAMILY SSF48140 1 141 6.54E-55 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 PIRSF PIRSF000106 51 426 7.4E-89 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 SUPERFAMILY SSF53223 26 172 5.47E-52 T 23-10-2018 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 Pfam PF03949 Malic enzyme, NAD binding domain 176 377 4.8E-26 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 Gene3D G3DSA:3.40.50.10380 14 171 6.8E-67 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 Pfam PF00390 Malic enzyme, N-terminal domain 31 162 5.3E-27 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 Gene3D G3DSA:3.40.50.720 172 440 6.0E-90 T 23-10-2018 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 SMART SM00919 174 396 2.1E-116 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 SUPERFAMILY SSF51735 174 423 1.2E-80 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 ProSitePatterns PS00331 Malic enzymes signature. 170 186 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TSIB_0123 750598dbccf5586b8b0c7a67f015a890 440 SMART SM01274 30 162 8.4E-73 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSIB_2044 c9e8216626388352238c69a7fac155ad 352 SUPERFAMILY SSF53448 1 304 8.92E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2044 c9e8216626388352238c69a7fac155ad 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 282 1.7E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2044 c9e8216626388352238c69a7fac155ad 352 Pfam PF00483 Nucleotidyl transferase 2 234 1.4E-50 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_2044 c9e8216626388352238c69a7fac155ad 352 Gene3D G3DSA:2.160.10.10 240 351 2.2E-12 T 23-10-2018 TSIB_2044 c9e8216626388352238c69a7fac155ad 352 Gene3D G3DSA:3.90.550.10 1 239 4.8E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2044 c9e8216626388352238c69a7fac155ad 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 1.4E-162 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form TSIB_1665 ce91712087fb2824647c2d39548b6b32 280 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 28 278 40.397 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 TSIB_1665 ce91712087fb2824647c2d39548b6b32 280 Gene3D G3DSA:3.40.50.150 90 280 7.9E-58 T 23-10-2018 TSIB_1665 ce91712087fb2824647c2d39548b6b32 280 SUPERFAMILY SSF53335 21 278 2.13E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1665 ce91712087fb2824647c2d39548b6b32 280 Pfam PF02475 Met-10+ like-protein 31 225 8.1E-69 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TSIB_1665 ce91712087fb2824647c2d39548b6b32 280 Gene3D G3DSA:3.30.300.110 21 88 5.9E-28 T 23-10-2018 TSIB_0385 9536c669726d9e3f89b7b6474d487bbe 104 Gene3D G3DSA:1.10.10.1410 1 58 8.0E-30 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0385 9536c669726d9e3f89b7b6474d487bbe 104 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 101 14.286 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0385 9536c669726d9e3f89b7b6474d487bbe 104 Pfam PF00428 60s Acidic ribosomal protein 16 103 3.9E-21 T 23-10-2018 TSIB_0385 9536c669726d9e3f89b7b6474d487bbe 104 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 104 1.3E-41 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 TSIB_2040 f0f86e215aed5d78676ef342d6a8db78 136 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 34 128 5.3E-8 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TSIB_2040 f0f86e215aed5d78676ef342d6a8db78 136 Gene3D G3DSA:3.10.450.620 19 128 2.0E-6 T 23-10-2018 TSIB_1548 61ec0852bbb5dad329332e0a47b79e63 323 Pfam PF12679 ABC-2 family transporter protein 5 322 9.3E-34 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 168 1.1E-28 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 SUPERFAMILY SSF52490 3 199 5.76E-42 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 Gene3D G3DSA:3.40.50.1440 1 363 8.1E-89 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 PRINTS PR00423 Cell division protein FtsZ signature 93 113 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 PRINTS PR00423 Cell division protein FtsZ signature 123 144 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 PRINTS PR00423 Cell division protein FtsZ signature 183 205 3.4E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.584 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 TSIB_0035 9320b7d6be406060c10c1b6c9e752007 367 SMART SM00864 2 199 2.0E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 SUPERFAMILY SSF53850 34 345 4.76E-74 T 23-10-2018 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 Gene3D G3DSA:3.40.190.10 137 340 3.3E-114 T 23-10-2018 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 Pfam PF13343 Bacterial extracellular solute-binding protein 85 306 1.3E-32 T 23-10-2018 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 Gene3D G3DSA:3.40.190.10 39 313 3.3E-114 T 23-10-2018 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 35 339 1.9E-93 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TSIB_0369 3b51cd8a8138115cd9a3381f12b701d4 357 PIRSF PIRSF002825 4 344 9.1E-53 T 23-10-2018 IPR026045 Ferric binding protein TSIB_1082 f26025457c55d7324661150a85f71bff 186 Gene3D G3DSA:3.40.50.620 1 177 4.3E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1082 f26025457c55d7324661150a85f71bff 186 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 60 1.3E-16 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_1082 f26025457c55d7324661150a85f71bff 186 Pfam PF01467 Cytidylyltransferase-like 4 135 4.3E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_1082 f26025457c55d7324661150a85f71bff 186 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 186 84.745 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TSIB_1082 f26025457c55d7324661150a85f71bff 186 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 167 8.9E-67 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TSIB_1082 f26025457c55d7324661150a85f71bff 186 SUPERFAMILY SSF52374 1 165 1.1E-35 T 23-10-2018 TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 SUPERFAMILY SSF51306 32 102 2.75E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 23-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 3.4E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 3.4E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 Pfam PF00717 Peptidase S24-like 34 94 7.1E-12 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 Gene3D G3DSA:2.10.109.10 36 132 2.2E-8 T 23-10-2018 TSIB_1249 8fd29dafb1c3b9ee22898d1a40467eff 356 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 2 152 1.9E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_0976 26b287ef3ebf872acae401331cd2ef29 208 Pfam PF01997 Translin family 22 183 7.6E-14 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 TSIB_0976 26b287ef3ebf872acae401331cd2ef29 208 Gene3D G3DSA:1.20.58.2140 6 203 2.5E-64 T 23-10-2018 TSIB_0976 26b287ef3ebf872acae401331cd2ef29 208 SUPERFAMILY SSF74784 4 184 1.44E-38 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 TSIB_0939 e033a0437668588e65d68305436b565d 226 PIRSF PIRSF000887 1 224 1.4E-57 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TSIB_0939 e033a0437668588e65d68305436b565d 226 Pfam PF00149 Calcineurin-like phosphoesterase 17 112 8.7E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_0939 e033a0437668588e65d68305436b565d 226 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 6 220 2.2E-48 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like TSIB_0939 e033a0437668588e65d68305436b565d 226 Gene3D G3DSA:3.60.21.10 17 149 2.3E-11 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0939 e033a0437668588e65d68305436b565d 226 SUPERFAMILY SSF56300 17 147 8.39E-14 T 23-10-2018 TSIB_1042 cbf59182dd76ae644c6eac7571074259 576 SUPERFAMILY SSF56300 349 561 3.32E-37 T 23-10-2018 TSIB_1042 cbf59182dd76ae644c6eac7571074259 576 Pfam PF00149 Calcineurin-like phosphoesterase 349 527 4.2E-12 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_1042 cbf59182dd76ae644c6eac7571074259 576 Gene3D G3DSA:3.60.21.10 356 574 1.4E-20 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0271 b89b2a823763d76784755a2475df1e02 788 SUPERFAMILY SSF52009 352 460 1.7E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 380 452 1.9E-27 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 674 692 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Gene3D G3DSA:3.50.30.10 354 460 9.1E-44 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 SUPERFAMILY SSF56059 2 380 3.06E-107 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Gene3D G3DSA:3.30.470.20 197 353 3.8E-53 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 PIRSF PIRSF000854 1 773 7.3E-209 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 483 767 2.7E-95 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 350 5.0E-119 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 6 769 3.5E-287 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Gene3D G3DSA:3.30.1490.20 1 196 6.7E-74 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 SUPERFAMILY SSF51621 483 774 8.38E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 674 689 2.6E-13 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 727 739 2.6E-13 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 510 529 2.6E-13 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 691 706 2.6E-13 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 Gene3D G3DSA:3.20.20.60 461 787 2.0E-104 T 23-10-2018 TSIB_0271 b89b2a823763d76784755a2475df1e02 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 411 422 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 SUPERFAMILY SSF55257 12 268 7.07E-31 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 258 1.8E-18 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 39 79 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 14 268 33.439 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Gene3D G3DSA:3.30.1360.10 17 262 1.1E-94 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 SUPERFAMILY SSF56553 50 160 2.62E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Gene3D G3DSA:2.170.120.12 51 158 1.1E-94 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 159 2.2E-28 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 SMART SM00662 25 265 1.0E-74 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0342 037a667edc750cfcbaafadf8b3c2ba82 271 Gene3D G3DSA:3.30.70.3110 168 229 1.1E-94 T 23-10-2018 TSIB_0910 74b8615bc4fa52a7859545c6a7a16cbb 362 SUPERFAMILY SSF56266 2 359 2.43E-108 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSIB_0910 74b8615bc4fa52a7859545c6a7a16cbb 362 Pfam PF03576 Peptidase family S58 19 339 4.3E-117 T 23-10-2018 IPR005321 Peptidase S58, DmpA TSIB_0910 74b8615bc4fa52a7859545c6a7a16cbb 362 Gene3D G3DSA:3.60.70.12 1 361 2.5E-157 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSIB_1733 0487ae87b00dece8bd900b9b4a306580 117 Gene3D G3DSA:3.30.310.70 1 117 9.4E-27 T 23-10-2018 IPR035923 TT1751-like domain superfamily TSIB_1733 0487ae87b00dece8bd900b9b4a306580 117 PIRSF PIRSF021774 1 116 3.3E-26 T 23-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 TSIB_1733 0487ae87b00dece8bd900b9b4a306580 117 SUPERFAMILY SSF103247 4 115 1.18E-25 T 23-10-2018 IPR035923 TT1751-like domain superfamily TSIB_1733 0487ae87b00dece8bd900b9b4a306580 117 Pfam PF03625 Domain of unknown function DUF302 39 93 2.6E-17 T 23-10-2018 IPR005180 Domain of unknown function DUF302 TSIB_0997 2a819dddb59759124dab8e4fcd323cbc 155 Gene3D G3DSA:3.90.79.10 4 151 3.4E-28 T 23-10-2018 TSIB_0997 2a819dddb59759124dab8e4fcd323cbc 155 PRINTS PR00502 NUDIX hydrolase family signature 32 46 8.7E-5 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSIB_0997 2a819dddb59759124dab8e4fcd323cbc 155 PRINTS PR00502 NUDIX hydrolase family signature 47 62 8.7E-5 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSIB_0997 2a819dddb59759124dab8e4fcd323cbc 155 SUPERFAMILY SSF55811 2 142 3.93E-25 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSIB_0997 2a819dddb59759124dab8e4fcd323cbc 155 Pfam PF00293 NUDIX domain 3 123 8.0E-18 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 SUPERFAMILY SSF56228 1 209 2.49E-72 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 Gene3D G3DSA:1.10.599.10 237 607 5.9E-130 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 SUPERFAMILY SSF48310 211 620 5.1E-125 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 SMART SM00790 4 205 4.2E-115 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 8.7E-76 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 Gene3D G3DSA:3.60.9.10 1 209 1.6E-89 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 607 2.1E-109 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_0476 917304ba59846bbe02a435a803b8ae18 621 Gene3D G3DSA:1.10.569.10 239 419 5.9E-130 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 Gene3D G3DSA:1.10.10.10 292 365 2.0E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 Pfam PF01637 ATPase domain predominantly from Archaea 20 255 5.2E-27 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 Gene3D G3DSA:1.10.8.60 214 291 7.7E-25 T 23-10-2018 TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 SUPERFAMILY SSF46785 290 363 2.31E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 Gene3D G3DSA:3.40.50.300 6 213 9.1E-49 T 23-10-2018 TSIB_0732 dbbb8297d27411654e32964a3c50ad39 369 SUPERFAMILY SSF52540 6 288 7.28E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0100 ef13153b3704314c021bab66078b084f 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TSIB_0100 ef13153b3704314c021bab66078b084f 395 Gene3D G3DSA:3.90.1150.10 35 385 1.6E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0100 ef13153b3704314c021bab66078b084f 395 Pfam PF00155 Aminotransferase class I and II 39 383 2.4E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_0100 ef13153b3704314c021bab66078b084f 395 SUPERFAMILY SSF53383 4 391 1.46E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0100 ef13153b3704314c021bab66078b084f 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 3.5E-202 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TSIB_0100 ef13153b3704314c021bab66078b084f 395 Gene3D G3DSA:3.40.640.10 55 291 1.6E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0100 ef13153b3704314c021bab66078b084f 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 23 384 2.0E-129 T 23-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 SUPERFAMILY SSF46785 150 206 4.65E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 Gene3D G3DSA:1.10.10.10 165 224 2.4E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 SUPERFAMILY SSF46785 4 151 2.27E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 SMART SM00418 5 86 1.2E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 Gene3D G3DSA:1.10.10.10 2 77 2.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0990 c2871fef6c3e1c768b3c3e1a84086585 224 Pfam PF12840 Helix-turn-helix domain 5 58 2.7E-8 T 23-10-2018 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 140 160 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 Pfam PF00919 Uncharacterized protein family UPF0004 2 86 9.0E-20 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 Pfam PF04055 Radical SAM superfamily 140 312 5.2E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 SMART SM00729 136 354 1.5E-64 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 420 2.5E-132 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 Pfam PF01938 TRAM domain 365 423 8.3E-11 T 23-10-2018 IPR002792 TRAM domain TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 SUPERFAMILY SSF102114 125 362 1.15E-54 T 23-10-2018 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 Gene3D G3DSA:3.40.50.12160 1 125 1.5E-23 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 2 423 1.1E-139 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 TSIB_1027 6ec42dfaaff3ffd2afd2aa99b08f5787 424 Gene3D G3DSA:3.80.30.20 136 368 7.0E-78 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSIB_0134 9395765ed3254a8cf3e846b73f712294 281 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 214 273 3.4E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_0134 9395765ed3254a8cf3e846b73f712294 281 SUPERFAMILY SSF46785 214 273 3.21E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0134 9395765ed3254a8cf3e846b73f712294 281 Gene3D G3DSA:1.10.10.10 205 279 7.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0483 a6a0e5141038dc9fbf301fb2bcc49078 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 13 122 9.8E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSIB_0483 a6a0e5141038dc9fbf301fb2bcc49078 128 TIGRFAM TIGR00494 crcB: protein CrcB 12 126 2.9E-27 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSIB_0483 a6a0e5141038dc9fbf301fb2bcc49078 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 11 127 19.175 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSIB_0631 c42daef11acb42c14e0d05ff8eae5f93 823 Gene3D G3DSA:3.20.70.40 34 823 4.9E-279 T 23-10-2018 TSIB_0631 c42daef11acb42c14e0d05ff8eae5f93 823 Pfam PF01228 Glycine radical 701 804 2.2E-29 T 23-10-2018 IPR001150 Glycine radical domain GO:0003824 TSIB_0631 c42daef11acb42c14e0d05ff8eae5f93 823 SUPERFAMILY SSF51998 30 820 1.04E-228 T 23-10-2018 TSIB_0631 c42daef11acb42c14e0d05ff8eae5f93 823 Pfam PF02901 Pyruvate formate lyase-like 36 685 1.2E-218 T 23-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 SMART SM00865 238 355 5.7E-35 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 SUPERFAMILY SSF52490 36 239 2.62E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 22 361 2.0E-111 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 Gene3D G3DSA:3.40.50.1440 34 347 2.1E-98 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 SMART SM00864 37 236 1.4E-83 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 PRINTS PR00423 Cell division protein FtsZ signature 220 242 5.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 PRINTS PR00423 Cell division protein FtsZ signature 158 179 5.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 PRINTS PR00423 Cell division protein FtsZ signature 122 142 5.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 PRINTS PR00423 Cell division protein FtsZ signature 243 264 5.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 Pfam PF12327 FtsZ family, C-terminal domain 253 346 1.2E-22 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 2.1E-40 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 SUPERFAMILY SSF55307 238 352 9.61E-33 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TSIB_1331 7df9f125d094fa8779124c0b89cbfe6f 414 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 390 33.239 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSIB_0697 0246204755b0280d520f5a781fe302c6 356 SUPERFAMILY SSF102114 61 262 4.58E-23 T 23-10-2018 TSIB_0697 0246204755b0280d520f5a781fe302c6 356 SMART SM00729 54 267 8.6E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0697 0246204755b0280d520f5a781fe302c6 356 Gene3D G3DSA:3.20.20.70 57 295 8.8E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0697 0246204755b0280d520f5a781fe302c6 356 Pfam PF04055 Radical SAM superfamily 63 230 1.0E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0186 1482c7b725c8641bdb5bebbad2eab0d0 245 Gene3D G3DSA:3.40.50.150 23 218 7.7E-43 T 23-10-2018 TSIB_0186 1482c7b725c8641bdb5bebbad2eab0d0 245 SUPERFAMILY SSF53335 3 243 1.99E-45 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0186 1482c7b725c8641bdb5bebbad2eab0d0 245 Pfam PF13649 Methyltransferase domain 45 145 1.6E-22 T 23-10-2018 TSIB_0186 1482c7b725c8641bdb5bebbad2eab0d0 245 Gene3D G3DSA:2.20.25.110 153 196 7.7E-43 T 23-10-2018 TSIB_1505 c0e64ff1d227e8b81e09eba339ad2abf 279 Pfam PF00005 ABC transporter 19 170 4.4E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1505 c0e64ff1d227e8b81e09eba339ad2abf 279 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1505 c0e64ff1d227e8b81e09eba339ad2abf 279 SUPERFAMILY SSF52540 2 232 1.65E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1505 c0e64ff1d227e8b81e09eba339ad2abf 279 SMART SM00382 28 219 1.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1505 c0e64ff1d227e8b81e09eba339ad2abf 279 Gene3D G3DSA:3.40.50.300 1 272 1.9E-70 T 23-10-2018 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 Gene3D G3DSA:2.30.42.10 206 294 8.8E-17 T 23-10-2018 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 Pfam PF02163 Peptidase family M50 118 366 2.1E-20 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 SUPERFAMILY SSF50156 207 297 8.79E-17 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 Pfam PF13180 PDZ domain 209 275 6.6E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 106 125 3.1E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 158 170 3.1E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 142 157 3.1E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 126 140 3.1E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_1177 f45c006a0da00cce3adcb6829fc06528 380 SMART SM00228 195 266 0.0069 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 Gene3D G3DSA:3.90.1640.10 166 352 1.9E-26 T 23-10-2018 TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 Pfam PF02272 DHHA1 domain 365 477 3.1E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 SUPERFAMILY SSF51735 4 141 1.31E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 Gene3D G3DSA:3.40.50.720 1 147 5.1E-20 T 23-10-2018 TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 Pfam PF01368 DHH family 168 318 2.2E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 SUPERFAMILY SSF64182 165 456 1.23E-53 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TSIB_0981 89e78c1f1aa967bb0719ac04e0822e70 490 Pfam PF02254 TrkA-N domain 6 108 6.3E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 PIRSF PIRSF000371 2 301 7.6E-99 T 23-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 Gene3D G3DSA:3.30.70.20 74 107 3.4E-5 T 23-10-2018 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 SUPERFAMILY SSF54862 24 160 9.77E-28 T 23-10-2018 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 Gene3D G3DSA:3.20.20.70 2 72 3.7E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 Gene3D G3DSA:3.80.30.10 124 301 2.8E-60 T 23-10-2018 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 Pfam PF13353 4Fe-4S single cluster domain 16 184 4.5E-14 T 23-10-2018 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 Pfam PF04055 Radical SAM superfamily 24 232 4.5E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 6 293 4.6E-106 T 23-10-2018 TSIB_0629 1648447fde240644ad77dfc75e7b0c56 301 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 23-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 PIRSF PIRSF006392 1 406 2.3E-154 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 3 401 45.227 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 6 400 2.0E-136 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 Gene3D G3DSA:3.30.70.2130 80 229 2.4E-142 T 23-10-2018 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 SUPERFAMILY SSF53649 3 403 2.71E-42 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 Pfam PF01676 Metalloenzyme superfamily 4 398 1.6E-52 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 39 207 1.1E-53 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_1580 939dcb9f97b390e4a0c47df45fe668e2 410 Gene3D G3DSA:3.40.720.10 6 396 2.4E-142 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 SUPERFAMILY SSF53041 56 188 1.96E-26 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 SMART SM00857 57 180 8.4E-29 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 3.3E-16 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 SUPERFAMILY SSF46955 2 50 1.56E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 Gene3D G3DSA:3.40.50.1390 54 154 5.6E-29 T 23-10-2018 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 Pfam PF00239 Resolvase, N terminal domain 57 189 3.2E-26 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 Gene3D G3DSA:1.10.1660.10 2 52 1.4E-10 T 23-10-2018 TSIB_2042 6816d70fb3b4f8a5684c895aab81cf2f 202 Pfam PF12728 Helix-turn-helix domain 3 52 1.8E-14 T 23-10-2018 TSIB_1699 b01a4cba4b1ea9f4f20ea4a06dce7837 149 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 127 1.9E-26 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSIB_1699 b01a4cba4b1ea9f4f20ea4a06dce7837 149 Gene3D G3DSA:3.40.50.2300 4 136 6.2E-46 T 23-10-2018 TSIB_1699 b01a4cba4b1ea9f4f20ea4a06dce7837 149 SMART SM00226 4 130 1.5E-43 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSIB_1699 b01a4cba4b1ea9f4f20ea4a06dce7837 149 SUPERFAMILY SSF52788 6 128 1.05E-36 T 23-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TSIB_0264 d7e96565bd4369e17f42a039b69f38a9 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 351 4.4E-132 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TSIB_0264 d7e96565bd4369e17f42a039b69f38a9 355 PIRSF PIRSF009433 1 354 3.0E-145 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TSIB_0264 d7e96565bd4369e17f42a039b69f38a9 355 SUPERFAMILY SSF53067 1 304 2.98E-8 T 23-10-2018 TSIB_1808 96749cd3f21fec7de79f1de1ed979032 252 Gene3D G3DSA:3.40.1390.30 7 239 1.7E-76 T 23-10-2018 TSIB_1808 96749cd3f21fec7de79f1de1ed979032 252 SUPERFAMILY SSF102705 1 247 4.05E-70 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TSIB_1808 96749cd3f21fec7de79f1de1ed979032 252 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 250 5.5E-63 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TSIB_1808 96749cd3f21fec7de79f1de1ed979032 252 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 240 5.3E-58 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TSIB_1808 96749cd3f21fec7de79f1de1ed979032 252 Gene3D G3DSA:3.40.1390.30 97 223 1.7E-76 T 23-10-2018 TSIB_0674 7e0c834a24405fb83d09356f6602c051 279 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 106 247 1.2E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSIB_0674 7e0c834a24405fb83d09356f6602c051 279 SMART SM00478 110 268 2.7E-20 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSIB_0674 7e0c834a24405fb83d09356f6602c051 279 Gene3D G3DSA:1.10.340.30 100 215 3.1E-40 T 23-10-2018 TSIB_0674 7e0c834a24405fb83d09356f6602c051 279 SUPERFAMILY SSF48150 89 267 5.41E-35 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSIB_0674 7e0c834a24405fb83d09356f6602c051 279 Gene3D G3DSA:1.10.1670.40 79 263 3.1E-40 T 23-10-2018 TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 Gene3D G3DSA:2.40.50.140 1 70 6.5E-32 T 23-10-2018 TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 Pfam PF01200 Ribosomal protein S28e 4 66 2.9E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 SUPERFAMILY SSF50249 3 69 1.54E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0420 e56ad49ff7711d364da02acb7b25d49f 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 2.0E-17 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0605 ff25b241a8095651b1932940125fcdf0 100 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 6 100 28.421 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal TSIB_0605 ff25b241a8095651b1932940125fcdf0 100 ProSitePatterns PS01171 Ribosomal protein L21e signature. 41 66 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0605 ff25b241a8095651b1932940125fcdf0 100 SUPERFAMILY SSF50104 9 100 5.11E-30 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_0605 ff25b241a8095651b1932940125fcdf0 100 Pfam PF01157 Ribosomal protein L21e 9 99 2.2E-30 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0605 ff25b241a8095651b1932940125fcdf0 100 Gene3D G3DSA:2.30.30.70 5 100 2.5E-35 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 Gene3D G3DSA:1.10.10.460 162 208 7.1E-24 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 Pfam PF01351 Ribonuclease HII 5 200 7.1E-52 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 Gene3D G3DSA:3.30.420.10 2 161 3.1E-58 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 5 205 2.6E-78 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 SUPERFAMILY SSF53098 3 209 3.95E-60 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TSIB_0413 1d927e7b61090a17b7ece3c586da2981 224 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.288 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 TSIB_1991 aa8ce4db2bcbe99273a4c511f538908a 250 Pfam PF01939 Endonuclease NucS 26 244 2.3E-85 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TSIB_1991 aa8ce4db2bcbe99273a4c511f538908a 250 Gene3D G3DSA:3.40.1350.10 124 235 3.2E-42 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSIB_1991 aa8ce4db2bcbe99273a4c511f538908a 250 Gene3D G3DSA:2.70.180.20 1 123 9.1E-42 T 23-10-2018 TSIB_1991 aa8ce4db2bcbe99273a4c511f538908a 250 Hamap MF_00722 Endonuclease NucS [nucS]. 27 240 38.383 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TSIB_1204 f8cc5e28385cec0b6c02896b5ce73012 481 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 286 333 1.5E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TSIB_1204 f8cc5e28385cec0b6c02896b5ce73012 481 SUPERFAMILY SSF52540 159 326 6.31E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1204 f8cc5e28385cec0b6c02896b5ce73012 481 Gene3D G3DSA:3.40.50.720 37 167 1.6E-9 T 23-10-2018 TSIB_1204 f8cc5e28385cec0b6c02896b5ce73012 481 Gene3D G3DSA:3.40.50.300 235 338 4.0E-8 T 23-10-2018 TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 SUPERFAMILY SSF50998 113 409 1.73E-15 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 93 132 1.2E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 145 184 8.2E-6 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 355 393 0.0064 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 41 80 0.0058 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 154 184 7.7E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 SUPERFAMILY SSF50998 34 112 1.18E-5 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 Gene3D G3DSA:2.80.10.50 33 156 1.5E-5 T 23-10-2018 TSIB_0743 8d388c73d76fbdfd8b8813cde6911f03 510 Gene3D G3DSA:2.80.10.50 171 302 1.6E-7 T 23-10-2018 TSIB_1092 1f58e965f3a69a26771b1111de350e98 210 SUPERFAMILY SSF56784 2 205 4.99E-41 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_1092 1f58e965f3a69a26771b1111de350e98 210 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 171 2.0E-18 T 23-10-2018 TSIB_1092 1f58e965f3a69a26771b1111de350e98 210 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 172 1.5E-28 T 23-10-2018 TSIB_1092 1f58e965f3a69a26771b1111de350e98 210 Gene3D G3DSA:3.40.50.1000 1 201 7.9E-50 T 23-10-2018 IPR023214 HAD superfamily TSIB_1092 1f58e965f3a69a26771b1111de350e98 210 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 193 6.4E-52 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 SUPERFAMILY SSF46785 372 440 3.48E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 Pfam PF03551 Transcriptional regulator PadR-like family 376 439 2.2E-6 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 SUPERFAMILY SSF53686 2 359 9.04E-78 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 Gene3D G3DSA:3.40.50.1100 48 357 1.1E-96 T 23-10-2018 TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 SMART SM00418 365 443 1.1E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 353 1.4E-61 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 Gene3D G3DSA:1.10.10.10 370 441 2.0E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0898 8a65bc5ea2ef1eb844366299c7a3daf6 443 Gene3D G3DSA:3.40.50.1100 95 191 1.1E-96 T 23-10-2018 TSIB_0626 75cac8740e16eedd9a0f5516e9da2fed 187 SMART SM01022 8 109 5.8E-18 T 23-10-2018 IPR007374 ASCH domain TSIB_0626 75cac8740e16eedd9a0f5516e9da2fed 187 Gene3D G3DSA:2.30.130.30 7 108 3.0E-7 T 23-10-2018 TSIB_0626 75cac8740e16eedd9a0f5516e9da2fed 187 Pfam PF04266 ASCH domain 10 109 2.9E-20 T 23-10-2018 IPR007374 ASCH domain TSIB_0626 75cac8740e16eedd9a0f5516e9da2fed 187 SUPERFAMILY SSF88697 5 108 2.73E-18 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1857 73c250fa3514f64b5d03ecfde1559aae 321 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 218 295 1.7E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1857 73c250fa3514f64b5d03ecfde1559aae 321 Gene3D G3DSA:3.20.20.70 75 306 6.5E-12 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1857 73c250fa3514f64b5d03ecfde1559aae 321 SUPERFAMILY SSF102114 158 279 1.53E-11 T 23-10-2018 TSIB_1857 73c250fa3514f64b5d03ecfde1559aae 321 Pfam PF13186 Iron-sulfur cluster-binding domain 216 274 1.5E-6 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1239 14ebc1e48b21126abca7d73bf61aac96 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 424 2.8E-95 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TSIB_1239 14ebc1e48b21126abca7d73bf61aac96 427 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 341 361 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TSIB_1239 14ebc1e48b21126abca7d73bf61aac96 427 Pfam PF00860 Permease family 17 393 6.2E-97 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 Pfam PF01912 eIF-6 family 20 220 1.2E-68 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 PIRSF PIRSF006413 17 243 9.8E-77 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 SMART SM00654 19 221 2.4E-101 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 SUPERFAMILY SSF55909 18 241 2.55E-72 T 23-10-2018 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 Hamap MF_00032 Translation initiation factor 6 [eif6]. 6 243 92.47 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 Gene3D G3DSA:3.75.10.10 15 242 5.0E-80 T 23-10-2018 TSIB_0646 74526f5a0fb3c5a94889a7d5ec4a27e8 243 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 20 241 2.7E-66 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 SUPERFAMILY SSF50182 101 167 2.75E-16 T 23-10-2018 IPR010920 LSM domain superfamily TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 SUPERFAMILY SSF82689 168 266 9.81E-34 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 Gene3D G3DSA:2.30.30.60 117 166 4.9E-17 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 Gene3D G3DSA:3.30.70.100 167 261 1.4E-30 T 23-10-2018 TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 SUPERFAMILY SSF82861 16 100 9.55E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSIB_0487 605811b53bb3e44ed895d5a5c992f16e 270 Pfam PF00924 Mechanosensitive ion channel 60 256 1.8E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 147 13.598 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 Gene3D G3DSA:4.10.990.10 4 62 2.0E-9 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 Gene3D G3DSA:3.100.10.10 63 147 7.4E-22 T 23-10-2018 TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 144 6.0E-19 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TSIB_0311 bb0f54589fe47931c8d3b7ba57afce62 147 SUPERFAMILY SSF52080 5 146 6.67E-33 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 Pfam PF08646 Replication factor-A C terminal domain 196 281 1.0E-9 T 23-10-2018 IPR013955 Replication factor A, C-terminal TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 Pfam PF01336 OB-fold nucleic acid binding domain 75 152 3.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 SUPERFAMILY SSF50249 181 347 7.54E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 SUPERFAMILY SSF50249 60 178 8.23E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 Gene3D G3DSA:2.40.50.140 62 167 1.4E-21 T 23-10-2018 TSIB_0707 75e5ab2bbf7a50214593d50a3bb6fb31 353 Gene3D G3DSA:2.40.50.140 168 350 3.3E-12 T 23-10-2018 TSIB_2036 7cfc2473e292ce652910ff6e76c6d622 413 Pfam PF13635 Domain of unknown function (DUF4143) 251 354 5.7E-13 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TSIB_2036 7cfc2473e292ce652910ff6e76c6d622 413 SUPERFAMILY SSF52540 30 191 1.54E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_2036 7cfc2473e292ce652910ff6e76c6d622 413 Pfam PF13173 AAA domain 40 158 4.5E-30 T 23-10-2018 TSIB_0584 4da348b0cc2d67562168263854584438 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 143 291 9.6E-7 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TSIB_0584 4da348b0cc2d67562168263854584438 311 PIRSF PIRSF005303 1 308 2.3E-92 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSIB_0584 4da348b0cc2d67562168263854584438 311 Gene3D G3DSA:3.90.650.10 138 308 1.8E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0584 4da348b0cc2d67562168263854584438 311 SUPERFAMILY SSF56042 136 295 1.35E-40 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSIB_0584 4da348b0cc2d67562168263854584438 311 SUPERFAMILY SSF55326 7 132 5.58E-28 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_0584 4da348b0cc2d67562168263854584438 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 308 26.7 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSIB_0584 4da348b0cc2d67562168263854584438 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 23 132 1.9E-15 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TSIB_0584 4da348b0cc2d67562168263854584438 311 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 308 6.3E-87 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSIB_0584 4da348b0cc2d67562168263854584438 311 Gene3D G3DSA:3.30.1330.10 1 137 2.3E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSIB_1703 05b7253a15eadf1b1488ceb638bc9758 101 Pfam PF00085 Thioredoxin 4 97 2.1E-14 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 TSIB_1703 05b7253a15eadf1b1488ceb638bc9758 101 Gene3D G3DSA:3.40.30.10 3 101 2.6E-17 T 23-10-2018 TSIB_1703 05b7253a15eadf1b1488ceb638bc9758 101 SUPERFAMILY SSF52833 14 99 1.04E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1703 05b7253a15eadf1b1488ceb638bc9758 101 ProSitePatterns PS00194 Thioredoxin family active site. 17 35 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSIB_1569 9f3a62babdd12cc886cfa0937a6e41c8 381 Gene3D G3DSA:3.90.1150.10 19 374 7.7E-134 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1569 9f3a62babdd12cc886cfa0937a6e41c8 381 Pfam PF00266 Aminotransferase class-V 40 365 1.7E-36 T 23-10-2018 IPR000192 Aminotransferase class V domain TSIB_1569 9f3a62babdd12cc886cfa0937a6e41c8 381 Gene3D G3DSA:3.40.640.10 29 274 7.7E-134 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1569 9f3a62babdd12cc886cfa0937a6e41c8 381 PIRSF PIRSF000524 11 381 2.9E-94 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TSIB_1569 9f3a62babdd12cc886cfa0937a6e41c8 381 SUPERFAMILY SSF53383 16 378 1.26E-91 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 SUPERFAMILY SSF50447 2 86 4.06E-24 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 Pfam PF01247 Ribosomal protein L35Ae 2 86 5.4E-19 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 55 76 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 Gene3D G3DSA:2.40.10.190 1 87 3.1E-28 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 3 86 1.0E-27 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0516 0a6df1dbc164e0773c92fe9825aeb277 87 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 3 87 23.933 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1534 041f7f015dcffd5cee96deaefb8beffc 527 Gene3D G3DSA:3.90.226.10 4 264 3.5E-94 T 23-10-2018 TSIB_1534 041f7f015dcffd5cee96deaefb8beffc 527 Pfam PF01039 Carboxyl transferase domain 33 525 1.4E-202 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSIB_1534 041f7f015dcffd5cee96deaefb8beffc 527 Gene3D G3DSA:3.90.226.10 265 527 3.4E-95 T 23-10-2018 TSIB_1534 041f7f015dcffd5cee96deaefb8beffc 527 SUPERFAMILY SSF52096 7 262 1.61E-76 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSIB_1534 041f7f015dcffd5cee96deaefb8beffc 527 SUPERFAMILY SSF52096 260 527 3.32E-92 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSIB_1573 8b1044ae9a1e5e3b67688920817767b7 465 Pfam PF03606 C4-dicarboxylate anaerobic carrier 12 457 1.3E-88 T 23-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 Pfam PF07549 SecD/SecF GG Motif 26 51 9.8E-5 T 23-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 Pfam PF02355 Protein export membrane protein 333 488 5.6E-15 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 Gene3D G3DSA:1.20.1640.10 312 503 6.7E-11 T 23-10-2018 TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 SUPERFAMILY SSF82866 304 490 9.68E-25 T 23-10-2018 TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 Gene3D G3DSA:3.30.70.3400 33 114 2.3E-8 T 23-10-2018 TSIB_1800 7adc74481705312e3d58e084f9159c4b 506 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 4 504 18.691 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal TSIB_0410 4e13c4f458144a399a3054ff6c19c4dc 212 Pfam PF01914 MarC family integral membrane protein 8 210 2.7E-61 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSIB_0410 4e13c4f458144a399a3054ff6c19c4dc 212 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 206 4.9E-61 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSIB_1344 843656caeb9945ac6973c3b3ff5dc483 53 Gene3D G3DSA:2.20.28.30 5 53 9.3E-21 T 23-10-2018 TSIB_1344 843656caeb9945ac6973c3b3ff5dc483 53 SMART SM00659 8 53 7.2E-16 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_1344 843656caeb9945ac6973c3b3ff5dc483 53 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 10 43 1.4E-8 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_1344 843656caeb9945ac6973c3b3ff5dc483 53 SUPERFAMILY SSF63393 7 52 3.66E-12 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TSIB_1344 843656caeb9945ac6973c3b3ff5dc483 53 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 10 53 15.886 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_1732 3a85c0dc742b65b26ae7c4884b23cc59 420 SUPERFAMILY SSF52833 37 174 2.66E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1732 3a85c0dc742b65b26ae7c4884b23cc59 420 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 197 402 9.9E-12 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TSIB_1732 3a85c0dc742b65b26ae7c4884b23cc59 420 Gene3D G3DSA:3.40.30.10 24 178 1.6E-10 T 23-10-2018 TSIB_0297 ded1f5e00e59882b22056251033944a6 122 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 45 120 20.359 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 TSIB_0297 ded1f5e00e59882b22056251033944a6 122 SUPERFAMILY SSF101744 38 121 1.73E-24 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 TSIB_0297 ded1f5e00e59882b22056251033944a6 122 Gene3D G3DSA:2.30.30.210 17 122 3.8E-37 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 TSIB_0297 ded1f5e00e59882b22056251033944a6 122 SMART SM00538 37 122 6.3E-33 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TSIB_0297 ded1f5e00e59882b22056251033944a6 122 Pfam PF01868 Domain of unknown function UPF0086 42 121 2.2E-22 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TSIB_1018 98fefce6ed6cfab8aacadcad0f8b7931 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 13 214 9.0E-42 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TSIB_1018 98fefce6ed6cfab8aacadcad0f8b7931 215 SUPERFAMILY SSF109755 14 208 1.62E-9 T 23-10-2018 TSIB_1018 98fefce6ed6cfab8aacadcad0f8b7931 215 Gene3D G3DSA:1.20.58.220 3 211 2.4E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_1018 98fefce6ed6cfab8aacadcad0f8b7931 215 Pfam PF01865 Protein of unknown function DUF47 7 211 1.4E-45 T 23-10-2018 IPR018445 Putative phosphate transport regulator TSIB_1949 32114066c53761436c5f116f4f677c77 276 Pfam PF00294 pfkB family carbohydrate kinase 3 271 5.5E-43 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TSIB_1949 32114066c53761436c5f116f4f677c77 276 Gene3D G3DSA:3.40.1190.20 1 275 3.2E-65 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1949 32114066c53761436c5f116f4f677c77 276 SUPERFAMILY SSF53613 1 272 2.96E-60 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1949 32114066c53761436c5f116f4f677c77 276 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 229 242 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSIB_0142 ba7f42d204a57d9212ed110765efa727 173 Gene3D G3DSA:3.40.50.300 1 151 2.6E-30 T 23-10-2018 TSIB_0142 ba7f42d204a57d9212ed110765efa727 173 SUPERFAMILY SSF52540 1 92 2.48E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0142 ba7f42d204a57d9212ed110765efa727 173 Pfam PF13732 Domain of unknown function (DUF4162) 82 166 6.5E-9 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 TSIB_0142 ba7f42d204a57d9212ed110765efa727 173 Pfam PF00005 ABC transporter 1 28 1.3E-5 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0126 991229b823570df5c754c4201272bfbd 350 Gene3D G3DSA:3.40.50.150 100 325 1.8E-84 T 23-10-2018 TSIB_0126 991229b823570df5c754c4201272bfbd 350 Gene3D G3DSA:1.10.10.10 1 82 2.5E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0126 991229b823570df5c754c4201272bfbd 350 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 350 49.249 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TSIB_0126 991229b823570df5c754c4201272bfbd 350 SUPERFAMILY SSF53335 163 258 3.2E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0126 991229b823570df5c754c4201272bfbd 350 PIRSF PIRSF005895 1 350 2.6E-156 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TSIB_0126 991229b823570df5c754c4201272bfbd 350 Pfam PF01861 Protein of unknown function DUF43 105 349 1.6E-117 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 3.1E-93 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 Gene3D G3DSA:3.40.50.10470 115 310 8.2E-83 T 23-10-2018 TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 Gene3D G3DSA:1.20.120.420 1 114 9.4E-39 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 SUPERFAMILY SSF100950 3 311 3.21E-98 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 Pfam PF01008 Initiation factor 2 subunit family 18 299 2.4E-89 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TSIB_0548 404e3fbab742e8128aa850445c9ada97 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 7 312 8.4E-139 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 PIRSF PIRSF006373 4 176 5.1E-69 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 Hamap MF_01909 Transcription factor E [tfe]. 8 171 26.758 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 Pfam PF02002 TFIIE alpha subunit 14 115 2.1E-25 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 TIGRFAM TIGR00373 TIGR00373: transcription factor E 17 172 6.1E-50 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 Pfam PF04423 Rad50 zinc hook motif 141 172 6.3E-5 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 SUPERFAMILY SSF46785 11 91 4.28E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 SMART SM00531 24 163 3.4E-55 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TSIB_1374 3c7db60d09d6a25a6f73375fe4abe5f6 176 Gene3D G3DSA:1.10.10.10 8 93 2.4E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_2050 8f2865ec18a86a6f867f0246efed3610 306 Pfam PF00535 Glycosyl transferase family 2 1 124 1.3E-36 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_2050 8f2865ec18a86a6f867f0246efed3610 306 Gene3D G3DSA:3.90.550.10 1 243 7.5E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2050 8f2865ec18a86a6f867f0246efed3610 306 SUPERFAMILY SSF53448 1 223 1.13E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 PIRSF PIRSF005622 1 369 4.8E-141 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 Gene3D G3DSA:3.40.50.11740 61 302 1.4E-107 T 23-10-2018 TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 Gene3D G3DSA:3.40.50.11750 17 262 1.4E-107 T 23-10-2018 TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 Pfam PF01924 Hydrogenase formation hypA family 11 366 1.9E-134 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 Gene3D G3DSA:1.10.10.2140 317 369 1.0E-26 T 23-10-2018 TSIB_1434 9765cc6f11c0cd37e6743129be7efc5d 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 7 366 4.2E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 SUPERFAMILY SSF51230 515 589 3.8E-25 T 23-10-2018 IPR011053 Single hybrid motif TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 Gene3D G3DSA:3.20.20.70 1 451 1.7E-167 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 Pfam PF00364 Biotin-requiring enzyme 523 589 3.9E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 546 563 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 Pfam PF02436 Conserved carboxylase domain 290 475 1.8E-58 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 Gene3D G3DSA:2.40.50.100 519 589 3.6E-28 T 23-10-2018 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 SUPERFAMILY SSF51569 2 299 1.45E-84 T 23-10-2018 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 4 586 8.8E-230 T 23-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 Pfam PF00682 HMGL-like 2 266 1.2E-42 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSIB_0231 46f59734db0f53a2062f574c2b6df527 590 SUPERFAMILY SSF89000 295 449 1.8E-54 T 23-10-2018 TSIB_0031 3b509e24694c17a333654f8524f907c0 199 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 189 1.3E-61 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 TSIB_0031 3b509e24694c17a333654f8524f907c0 199 SUPERFAMILY SSF53335 3 180 1.2E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0031 3b509e24694c17a333654f8524f907c0 199 Pfam PF13847 Methyltransferase domain 37 153 3.0E-16 T 23-10-2018 IPR025714 Methyltransferase domain TSIB_0031 3b509e24694c17a333654f8524f907c0 199 Gene3D G3DSA:3.40.50.150 14 194 1.5E-40 T 23-10-2018 TSIB_0256 4062cb3e20cce861765fadae679e0232 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 426 1.4E-89 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0256 4062cb3e20cce861765fadae679e0232 458 Pfam PF01554 MatE 26 186 6.2E-38 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0256 4062cb3e20cce861765fadae679e0232 458 Pfam PF01554 MatE 248 413 1.1E-28 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_0256 4062cb3e20cce861765fadae679e0232 458 PIRSF PIRSF006603 3 455 7.7E-101 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSIB_1855 c3595acb10ba4cd3985feb5bd633097c 236 Pfam PF00899 ThiF family 13 234 1.1E-57 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TSIB_1855 c3595acb10ba4cd3985feb5bd633097c 236 SUPERFAMILY SSF69572 9 232 1.1E-77 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TSIB_1855 c3595acb10ba4cd3985feb5bd633097c 236 Gene3D G3DSA:3.40.50.720 5 236 7.9E-71 T 23-10-2018 TSIB_0235 3164dbedb941548e64cfdeb9e4e56851 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 5.5E-75 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 TSIB_0235 3164dbedb941548e64cfdeb9e4e56851 330 SUPERFAMILY SSF52540 12 317 4.25E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0235 3164dbedb941548e64cfdeb9e4e56851 330 Gene3D G3DSA:3.40.50.300 6 330 2.6E-85 T 23-10-2018 TSIB_0235 3164dbedb941548e64cfdeb9e4e56851 330 Pfam PF02374 Anion-transporting ATPase 12 327 9.1E-76 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TSIB_0595 73ca4e598713d666938c0d5ba90f8227 42 Gene3D G3DSA:3.40.50.1010 1 41 3.9E-6 T 23-10-2018 TSIB_0595 73ca4e598713d666938c0d5ba90f8227 42 SUPERFAMILY SSF88723 2 37 2.02E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0595 73ca4e598713d666938c0d5ba90f8227 42 Pfam PF01850 PIN domain 1 37 1.3E-10 T 23-10-2018 IPR002716 PIN domain TSIB_0174 13882265b63611447b0efcb1741744dc 468 SUPERFAMILY SSF47323 308 465 8.5E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0174 13882265b63611447b0efcb1741744dc 468 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 465 6.3E-178 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 SUPERFAMILY SSF52374 2 306 4.35E-106 T 23-10-2018 TSIB_0174 13882265b63611447b0efcb1741744dc 468 SMART SM00840 348 409 1.6E-12 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 8 306 1.2E-137 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 Gene3D G3DSA:3.40.50.620 1 297 3.4E-144 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0174 13882265b63611447b0efcb1741744dc 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 214 235 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 18 29 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 183 201 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 54 63 3.8E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 Gene3D G3DSA:1.20.120.640 298 465 3.1E-37 T 23-10-2018 TSIB_0174 13882265b63611447b0efcb1741744dc 468 Pfam PF09190 DALR domain 349 407 5.5E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSIB_0174 13882265b63611447b0efcb1741744dc 468 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 466 38.081 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSIB_1851 2e127741e6e664733a237796886d9d69 527 SUPERFAMILY SSF102114 158 401 3.53E-36 T 23-10-2018 TSIB_1851 2e127741e6e664733a237796886d9d69 527 Pfam PF02310 B12 binding domain 18 132 1.9E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSIB_1851 2e127741e6e664733a237796886d9d69 527 Gene3D G3DSA:3.40.50.280 26 148 3.4E-14 T 23-10-2018 TSIB_1851 2e127741e6e664733a237796886d9d69 527 Pfam PF04055 Radical SAM superfamily 196 363 9.1E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1851 2e127741e6e664733a237796886d9d69 527 Gene3D G3DSA:3.80.30.20 190 397 1.0E-25 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSIB_1851 2e127741e6e664733a237796886d9d69 527 SUPERFAMILY SSF52242 51 146 3.66E-8 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSIB_1851 2e127741e6e664733a237796886d9d69 527 SMART SM00729 192 409 3.4E-32 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0640 3d4aa11884d4d4024cf60664cd9e7f1a 387 Gene3D G3DSA:3.30.9.10 85 314 6.7E-134 T 23-10-2018 TSIB_0640 3d4aa11884d4d4024cf60664cd9e7f1a 387 Pfam PF01266 FAD dependent oxidoreductase 7 354 5.4E-77 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSIB_0640 3d4aa11884d4d4024cf60664cd9e7f1a 387 SUPERFAMILY SSF51905 5 378 4.73E-63 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0640 3d4aa11884d4d4024cf60664cd9e7f1a 387 Gene3D G3DSA:3.50.50.60 7 359 6.7E-134 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0640 3d4aa11884d4d4024cf60664cd9e7f1a 387 SUPERFAMILY SSF54373 222 315 1.28E-10 T 23-10-2018 TSIB_0390 0bbdf730cba3dd19a7c0d1d589346b2e 397 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 5 389 41.764 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0390 0bbdf730cba3dd19a7c0d1d589346b2e 397 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 20 387 8.1E-152 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0390 0bbdf730cba3dd19a7c0d1d589346b2e 397 SUPERFAMILY SSF64484 24 388 5.04E-103 T 23-10-2018 TSIB_0390 0bbdf730cba3dd19a7c0d1d589346b2e 397 Gene3D G3DSA:1.10.150.390 337 382 2.2E-22 T 23-10-2018 TSIB_0390 0bbdf730cba3dd19a7c0d1d589346b2e 397 Pfam PF04998 RNA polymerase Rpb1, domain 5 55 336 4.2E-55 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 1.8E-28 T 23-10-2018 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 SUPERFAMILY SSF56784 1 232 2.67E-44 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 Gene3D G3DSA:1.10.150.240 16 101 3.0E-61 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 Gene3D G3DSA:3.40.50.1000 4 223 3.0E-61 T 23-10-2018 IPR023214 HAD superfamily TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 6.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 6.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 6.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 6.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 227 5.0E-62 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TSIB_1087 940a276f3c0979ec71dfae287e3c943f 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 195 3.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 95 224 7.4E-43 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 13 86 1.2E-20 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Gene3D G3DSA:2.40.50.140 3 83 4.2E-29 T 23-10-2018 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 SUPERFAMILY SSF50104 96 239 1.26E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 PIRSF PIRSF002158 1 241 7.6E-73 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 SMART SM01382 93 225 6.4E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Gene3D G3DSA:4.10.950.10 165 241 7.8E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Gene3D G3DSA:2.30.30.30 87 164 3.6E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 SMART SM01383 13 87 5.3E-26 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 SUPERFAMILY SSF50249 4 94 8.57E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0291 149b4347db6cffa99c858ae0b8998e3b 241 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 3 240 41.771 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 ProSitePatterns PS01166 RNA polymerases beta chain signature. 874 886 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04566 RNA polymerase Rpb2, domain 4 519 580 1.4E-20 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04567 RNA polymerase Rpb2, domain 5 601 639 1.0E-7 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:3.90.1100.10 19 176 2.4E-11 T 23-10-2018 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:2.40.50.150 679 870 3.9E-145 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04561 RNA polymerase Rpb2, domain 2 173 346 2.1E-34 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:3.90.1110.10 177 333 2.2E-57 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04565 RNA polymerase Rpb2, domain 3 422 486 7.9E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04563 RNA polymerase beta subunit 26 379 4.2E-52 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:3.90.1800.10 1008 1116 1.8E-41 T 23-10-2018 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:2.40.270.10 649 1007 3.9E-145 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 519 1117 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Gene3D G3DSA:3.90.1100.10 334 508 6.3E-54 T 23-10-2018 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 SUPERFAMILY SSF64484 10 1116 0.0 T 23-10-2018 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF00562 RNA polymerase Rpb2, domain 6 649 1021 1.5E-131 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_0388 eb1fedc2708fbee4499f67da244c0d01 1118 Pfam PF04560 RNA polymerase Rpb2, domain 7 1023 1114 1.8E-30 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSIB_1915 120307603e2828a25088843188221184 137 Pfam PF03334 Na+/H+ antiporter subunit 11 94 4.4E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_1915 120307603e2828a25088843188221184 137 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 109 4.8E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_0607 4948cd59ea1ec2020899b3ce236e1a81 97 Gene3D G3DSA:2.20.28.10 1 97 8.2E-33 T 23-10-2018 TSIB_0607 4948cd59ea1ec2020899b3ce236e1a81 97 SUPERFAMILY SSF46785 1 94 4.9E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 SUPERFAMILY SSF54862 66 137 1.22E-17 T 23-10-2018 TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 20 280 5.0E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 SUPERFAMILY SSF52540 18 301 6.42E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 Pfam PF13187 4Fe-4S dicluster domain 85 130 1.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 Gene3D G3DSA:3.30.70.20 80 127 2.3E-9 T 23-10-2018 TSIB_0691 5a3a232e8ab6cb5524bd109b404bbf3b 303 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1300 d7685cd95937e3aaf8ad40b0c2285899 156 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 32 140 8.5E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1300 d7685cd95937e3aaf8ad40b0c2285899 156 SUPERFAMILY SSF56770 19 150 2.75E-51 T 23-10-2018 TSIB_1300 d7685cd95937e3aaf8ad40b0c2285899 156 Gene3D G3DSA:3.40.50.12280 1 156 1.3E-49 T 23-10-2018 TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 Gene3D G3DSA:3.90.230.10 137 365 5.0E-85 T 23-10-2018 TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 SUPERFAMILY SSF55920 103 359 8.9E-75 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 295 307 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 SUPERFAMILY SSF53092 3 136 3.53E-18 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 138 3.2E-17 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 Gene3D G3DSA:3.40.350.10 1 136 1.1E-34 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_0821 db673e7667edb4521ae56360fb8a65e8 365 Pfam PF00557 Metallopeptidase family M24 147 347 6.3E-66 T 23-10-2018 IPR000994 Peptidase M24 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 109 5.7E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 11 30 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 9.2E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 4.2E-37 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 SUPERFAMILY SSF55979 125 247 8.94E-31 T 23-10-2018 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 SUPERFAMILY SSF55979 3 126 7.73E-31 T 23-10-2018 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 144 245 7.1E-9 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 Gene3D G3DSA:3.70.10.10 2 242 2.3E-77 T 23-10-2018 TSIB_0565 3d3c555641d64c65b262fac9a37da74a 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.99 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TSIB_0424 530273f1257a8cbfd75839fb705a0712 267 Pfam PF11495 Archaeal transcriptional regulator TrmB 128 266 1.8E-5 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TSIB_0424 530273f1257a8cbfd75839fb705a0712 267 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 81 4.8E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_0424 530273f1257a8cbfd75839fb705a0712 267 Gene3D G3DSA:1.10.10.10 4 109 4.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0424 530273f1257a8cbfd75839fb705a0712 267 SUPERFAMILY SSF46785 11 99 6.34E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0424 530273f1257a8cbfd75839fb705a0712 267 Gene3D G3DSA:3.30.870.10 125 267 3.6E-73 T 23-10-2018 TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 2.6E-51 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 Gene3D G3DSA:1.10.940.10 5 150 4.7E-14 T 23-10-2018 IPR035926 NusB-like superfamily TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 1.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 1.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 1.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 1.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 1.8E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 SUPERFAMILY SSF48013 8 163 1.44E-19 T 23-10-2018 IPR035926 NusB-like superfamily TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 Pfam PF01029 NusB family 11 133 1.4E-16 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 Gene3D G3DSA:3.40.50.150 154 450 3.1E-77 T 23-10-2018 TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 191 449 1.6E-63 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSIB_0918 3f157118d848964a4cce615b1e656cd8 450 SUPERFAMILY SSF53335 148 450 1.98E-69 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0173 9f2792b110c37329e2fa2716d4a36fc9 314 Gene3D G3DSA:3.10.50.40 29 177 2.6E-50 T 23-10-2018 TSIB_0173 9f2792b110c37329e2fa2716d4a36fc9 314 Gene3D G3DSA:2.40.10.330 115 163 2.6E-50 T 23-10-2018 TSIB_0173 9f2792b110c37329e2fa2716d4a36fc9 314 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 27 177 3.9E-17 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TSIB_0173 9f2792b110c37329e2fa2716d4a36fc9 314 SUPERFAMILY SSF54534 26 179 3.14E-40 T 23-10-2018 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 Gene3D G3DSA:3.50.50.60 106 223 1.6E-96 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 SUPERFAMILY SSF51905 1 172 1.67E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 Gene3D G3DSA:3.30.390.30 299 356 4.7E-27 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 2.6E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 2.6E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 2.6E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 2.6E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 277 1.3E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 Gene3D G3DSA:3.50.50.60 3 277 1.6E-96 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 SUPERFAMILY SSF55424 291 351 3.57E-23 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 SUPERFAMILY SSF51905 114 289 2.96E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 6.2E-20 T 23-10-2018 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 6.2E-20 T 23-10-2018 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 6.2E-20 T 23-10-2018 TSIB_1897 352a76e9b1ac21e52098e1d7f966e936 363 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 6.2E-20 T 23-10-2018 TSIB_1575 585bb2f7597e26cfaa7681adfd7df6c3 350 Pfam PF08461 Ribonuclease R winged-helix domain 31 95 9.5E-16 T 23-10-2018 IPR013668 Ribonuclease R winged-helix domain TSIB_1575 585bb2f7597e26cfaa7681adfd7df6c3 350 SUPERFAMILY SSF46785 21 98 5.33E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1575 585bb2f7597e26cfaa7681adfd7df6c3 350 Pfam PF01995 Domain of unknown function DUF128 109 344 9.9E-64 T 23-10-2018 IPR002846 NrpR regulatory domain TSIB_1575 585bb2f7597e26cfaa7681adfd7df6c3 350 Gene3D G3DSA:3.30.70.1360 119 339 2.9E-28 T 23-10-2018 IPR036984 NrpR domain superfamily TSIB_1575 585bb2f7597e26cfaa7681adfd7df6c3 350 Gene3D G3DSA:3.30.70.1360 188 314 2.9E-28 T 23-10-2018 IPR036984 NrpR domain superfamily TSIB_0897 6a1228b5a10765a65b040625614bf150 648 SMART SM01027 433 557 2.0E-56 T 23-10-2018 IPR022712 Beta-Casp domain TSIB_0897 6a1228b5a10765a65b040625614bf150 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 7.5E-299 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea TSIB_0897 6a1228b5a10765a65b040625614bf150 648 SMART SM00322 102 172 0.006 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Gene3D G3DSA:3.60.15.10 191 628 5.1E-164 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Pfam PF17214 KH domain 9 76 2.7E-28 T 23-10-2018 IPR033769 KH domain, archaeal TSIB_0897 6a1228b5a10765a65b040625614bf150 648 SUPERFAMILY SSF54814 94 141 2.31E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Gene3D G3DSA:3.30.300.20 72 142 2.2E-66 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Gene3D G3DSA:3.30.300.230 17 176 2.2E-66 T 23-10-2018 TSIB_0897 6a1228b5a10765a65b040625614bf150 648 SMART SM00849 198 428 5.7E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0897 6a1228b5a10765a65b040625614bf150 648 SUPERFAMILY SSF56281 185 647 3.3E-130 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 350 1.2E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 4.8E-20 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Pfam PF10996 Beta-Casp domain 434 556 1.8E-24 T 23-10-2018 IPR022712 Beta-Casp domain TSIB_0897 6a1228b5a10765a65b040625614bf150 648 Gene3D G3DSA:3.40.50.10890 401 588 5.1E-164 T 23-10-2018 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 5.0E-54 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 SUPERFAMILY SSF46785 3 150 1.43E-59 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.693 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 Pfam PF01090 Ribosomal protein S19e 3 138 8.7E-57 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 Gene3D G3DSA:1.10.10.2700 1 150 9.6E-64 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0524 3880f9849d2fbe4b42635fa8a7bbf506 150 SMART SM01413 3 139 1.4E-88 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1173 98431c751f936440fee2fee8403bbf98 290 SUPERFAMILY SSF47240 55 200 5.1E-12 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1173 98431c751f936440fee2fee8403bbf98 290 Pfam PF09968 Uncharacterized protein domain (DUF2202) 60 220 1.6E-66 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TSIB_1173 98431c751f936440fee2fee8403bbf98 290 Gene3D G3DSA:1.20.1260.10 55 227 1.7E-70 T 23-10-2018 IPR012347 Ferritin-like TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 Gene3D G3DSA:3.40.30.10 1 115 2.7E-35 T 23-10-2018 TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 SUPERFAMILY SSF52833 6 116 4.6E-24 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 Gene3D G3DSA:3.40.30.10 118 223 6.7E-28 T 23-10-2018 TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 SUPERFAMILY SSF52833 120 222 6.4E-23 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 Pfam PF13192 Thioredoxin domain 135 221 5.6E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 Pfam PF13192 Thioredoxin domain 28 102 4.6E-6 T 23-10-2018 IPR012336 Thioredoxin-like fold TSIB_0991 3b8d983e1e880673fb419fd21a6c8b76 224 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 221 3.5E-86 T 23-10-2018 IPR011903 Glutaredoxin-like domain TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 3.6E-20 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 Gene3D G3DSA:1.10.287.310 1 65 7.5E-20 T 23-10-2018 TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.19 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 Pfam PF00831 Ribosomal L29 protein 4 61 5.4E-17 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0295 84cfc3432a1c710b7fa7e4f3f2f6d9b6 66 SUPERFAMILY SSF46561 1 61 2.62E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 SUPERFAMILY SSF64005 35 263 2.75E-86 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 Pfam PF01255 Putative undecaprenyl diphosphate synthase 45 267 2.1E-81 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 213 230 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 38 267 1.9E-86 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 Gene3D G3DSA:3.40.1180.10 23 268 3.2E-100 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSIB_1513 dfc0bc044ef2de542d1e4bf2a87a3c6d 268 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 38 268 39.393 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSIB_1901 f47f2c382bb3e2becb8b77947ca5554c 290 SUPERFAMILY SSF52518 8 264 5.69E-80 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1901 f47f2c382bb3e2becb8b77947ca5554c 290 Gene3D G3DSA:3.40.50.970 69 219 3.9E-26 T 23-10-2018 TSIB_1901 f47f2c382bb3e2becb8b77947ca5554c 290 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 203 264 5.7E-25 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal TSIB_1901 f47f2c382bb3e2becb8b77947ca5554c 290 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 199 2.2E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1901 f47f2c382bb3e2becb8b77947ca5554c 290 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 18 285 2.0E-111 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 Pfam PF17284 Spermidine synthase tetramerisation domain 3 53 7.1E-11 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 Pfam PF01564 Spermine/spermidine synthase domain 57 240 9.5E-52 T 23-10-2018 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 279 36.657 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 SUPERFAMILY SSF53335 3 279 2.57E-74 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 Gene3D G3DSA:2.30.140.10 1 53 5.3E-23 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 TIGRFAM TIGR00417 speE: spermidine synthase 3 273 8.1E-80 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 Gene3D G3DSA:3.40.50.150 55 280 1.2E-75 T 23-10-2018 TSIB_0851 8de6974df18220ec8286a34eaedd9694 284 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 77 90 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSIB_1873 6905a0845137ff9f2fdf1345e39ca6d3 156 Pfam PF00578 AhpC/TSA family 5 128 1.0E-34 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1873 6905a0845137ff9f2fdf1345e39ca6d3 156 PIRSF PIRSF000239 2 154 8.7E-26 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1873 6905a0845137ff9f2fdf1345e39ca6d3 156 SUPERFAMILY SSF52833 5 149 3.84E-47 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1873 6905a0845137ff9f2fdf1345e39ca6d3 156 Gene3D G3DSA:3.40.30.10 1 148 3.7E-47 T 23-10-2018 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 151 314 4.7E-30 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 SMART SM00859 2 123 1.8E-31 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 PIRSF PIRSF000148 1 334 4.5E-88 T 23-10-2018 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 SUPERFAMILY SSF55347 140 316 1.9E-37 T 23-10-2018 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 Gene3D G3DSA:3.30.360.10 142 311 4.3E-116 T 23-10-2018 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 121 3.4E-27 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 1 330 1.4E-136 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 Gene3D G3DSA:3.40.50.720 2 327 4.3E-116 T 23-10-2018 TSIB_1116 48b542ad0038bc30a6c5bce4e50f9019 334 SUPERFAMILY SSF51735 1 168 1.17E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0603 0856dd4090302a64eabb71d6fc009a60 213 Pfam PF04919 Protein of unknown function (DUF655) 29 205 2.8E-68 T 23-10-2018 IPR007003 Protein of unknown function DUF655 TSIB_0603 0856dd4090302a64eabb71d6fc009a60 213 Gene3D G3DSA:1.10.150.280 100 197 1.2E-40 T 23-10-2018 TSIB_0603 0856dd4090302a64eabb71d6fc009a60 213 Gene3D G3DSA:2.40.50.140 29 99 1.0E-21 T 23-10-2018 TSIB_0603 0856dd4090302a64eabb71d6fc009a60 213 SUPERFAMILY SSF160975 29 206 3.14E-88 T 23-10-2018 TSIB_0208 6cfb4beac1efb28db9917e533819dfd0 258 Gene3D G3DSA:3.20.20.150 2 257 2.8E-56 T 23-10-2018 TSIB_0208 6cfb4beac1efb28db9917e533819dfd0 258 SUPERFAMILY SSF51658 5 254 1.03E-44 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TSIB_0208 6cfb4beac1efb28db9917e533819dfd0 258 SMART SM00518 19 255 0.0019 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TSIB_0208 6cfb4beac1efb28db9917e533819dfd0 258 Pfam PF01261 Xylose isomerase-like TIM barrel 54 220 2.8E-24 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSIB_0947 a349d0240b5ee9ec285349d43a368236 249 PIRSF PIRSF009320 90 249 1.2E-9 T 23-10-2018 TSIB_0947 a349d0240b5ee9ec285349d43a368236 249 PIRSF PIRSF009320 1 82 5.6E-16 T 23-10-2018 TSIB_0947 a349d0240b5ee9ec285349d43a368236 249 SUPERFAMILY SSF52540 1 248 5.33E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0947 a349d0240b5ee9ec285349d43a368236 249 Gene3D G3DSA:3.40.50.300 1 249 2.5E-86 T 23-10-2018 TSIB_0947 a349d0240b5ee9ec285349d43a368236 249 Pfam PF13614 AAA domain 1 173 1.4E-63 T 23-10-2018 IPR025669 AAA domain TSIB_0741 97438ee39b44d6720cb575e29ad91d78 620 ProSitePatterns PS00018 EF-hand calcium-binding domain. 133 145 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site TSIB_0741 97438ee39b44d6720cb575e29ad91d78 620 Pfam PF04473 Transglutaminase-like domain 296 450 4.7E-50 T 23-10-2018 IPR007562 Transglutaminase-like domain TSIB_0741 97438ee39b44d6720cb575e29ad91d78 620 Gene3D G3DSA:4.10.1080.10 56 174 1.8E-6 T 23-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TSIB_0741 97438ee39b44d6720cb575e29ad91d78 620 Gene3D G3DSA:3.10.620.30 284 431 1.0E-6 T 23-10-2018 TSIB_0506 174042463f7c8efdb197eee79be2993c 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.435 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSIB_0506 174042463f7c8efdb197eee79be2993c 177 Gene3D G3DSA:3.40.50.1950 1 177 3.4E-74 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0506 174042463f7c8efdb197eee79be2993c 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 2.3E-71 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSIB_0506 174042463f7c8efdb197eee79be2993c 177 Pfam PF02441 Flavoprotein 1 156 6.2E-29 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSIB_0506 174042463f7c8efdb197eee79be2993c 177 SUPERFAMILY SSF52507 1 177 2.88E-59 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 Pfam PF01546 Peptidase family M20/M25/M40 75 441 9.0E-33 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 Gene3D G3DSA:3.40.630.10 8 229 8.1E-49 T 23-10-2018 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 109 146 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 Gene3D G3DSA:3.40.630.10 361 431 6.7E-14 T 23-10-2018 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 SUPERFAMILY SSF53187 11 444 7.29E-56 T 23-10-2018 TSIB_0175 c8627b7865bd7091b8189fca8c877b44 447 Gene3D G3DSA:3.30.70.360 321 360 6.7E-14 T 23-10-2018 TSIB_1568 77306c4ca851e43102e8d34de20fd8c0 197 SUPERFAMILY SSF52540 9 125 1.73E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1568 77306c4ca851e43102e8d34de20fd8c0 197 Pfam PF00437 Type II/IV secretion system protein 7 111 4.6E-8 T 23-10-2018 IPR001482 Type II/IV secretion system protein TSIB_1568 77306c4ca851e43102e8d34de20fd8c0 197 Gene3D G3DSA:3.40.50.300 3 131 6.6E-14 T 23-10-2018 TSIB_0162 34cd60472f52e7e36b1d7666f6542077 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 2.3E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0162 34cd60472f52e7e36b1d7666f6542077 248 SUPERFAMILY SSF161098 7 241 1.44E-48 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0162 34cd60472f52e7e36b1d7666f6542077 248 Gene3D G3DSA:1.10.3720.10 5 248 5.2E-66 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0962 84cb9eef9e0ccd13ce7bd8dcdd15ab76 281 Gene3D G3DSA:1.20.1540.10 8 196 1.2E-5 T 23-10-2018 IPR035952 Rhomboid-like superfamily TSIB_0962 84cb9eef9e0ccd13ce7bd8dcdd15ab76 281 Pfam PF01694 Rhomboid family 48 171 2.4E-5 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TSIB_0962 84cb9eef9e0ccd13ce7bd8dcdd15ab76 281 SUPERFAMILY SSF144091 8 185 1.27E-8 T 23-10-2018 TSIB_1400 bcc20087a87c2d5c5a2f06e7779b7333 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 7.9E-24 T 23-10-2018 TSIB_1400 bcc20087a87c2d5c5a2f06e7779b7333 133 SUPERFAMILY SSF54593 1 131 2.75E-33 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSIB_1400 bcc20087a87c2d5c5a2f06e7779b7333 133 Gene3D G3DSA:3.10.180.10 1 132 9.8E-42 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSIB_1400 bcc20087a87c2d5c5a2f06e7779b7333 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 2.3E-50 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TSIB_0815 5e6c4750c7c357bd354c664622bb7ec7 59 Pfam PF07650 KH domain 3 56 2.5E-6 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0815 5e6c4750c7c357bd354c664622bb7ec7 59 Gene3D G3DSA:3.30.300.20 5 58 2.8E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0815 5e6c4750c7c357bd354c664622bb7ec7 59 SUPERFAMILY SSF54814 11 57 3.84E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 SMART SM00981 74 168 1.8E-20 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 SUPERFAMILY SSF143437 3 176 8.55E-45 T 23-10-2018 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 370 6.8E-61 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Gene3D G3DSA:3.30.70.1510 2 83 1.1E-29 T 23-10-2018 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Gene3D G3DSA:3.30.2300.10 85 166 3.8E-29 T 23-10-2018 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Gene3D G3DSA:3.40.50.620 178 376 9.4E-62 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 367 4.0E-101 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 382 117.058 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 Pfam PF02926 THUMP domain 29 168 2.6E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_0351 5ea1c631ab8b9a12a569895c3092fb90 382 SUPERFAMILY SSF52402 178 337 1.09E-46 T 23-10-2018 TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 Pfam PF10150 Ribonuclease E/G family 144 255 2.3E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 SUPERFAMILY SSF159234 310 463 7.98E-30 T 23-10-2018 IPR035930 FomD-like superfamily TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 1 463 32.313 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 Pfam PF04167 Protein of unknown function (DUF402) 369 435 2.3E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 PIRSF PIRSF018644 1 463 1.0E-182 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TSIB_0107 1a6829e75a0890a49b0dd4b004e7d60b 463 Gene3D G3DSA:2.40.380.10 365 463 1.2E-5 T 23-10-2018 IPR035930 FomD-like superfamily TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 SMART SM00849 14 221 5.0E-22 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 421 2.4E-12 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 SUPERFAMILY SSF56281 2 438 2.41E-65 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 439 1.0E-162 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 Gene3D G3DSA:3.60.15.10 3 438 4.3E-134 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 Gene3D G3DSA:3.40.50.10710 215 374 4.3E-134 T 23-10-2018 TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 3.3E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1232 a98f652f9b1b8bb2091d9ba29854ddac 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 50.546 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 TSIB_1224 ffbf25a1cd5147790b4cdcef193a7823 125 Pfam PF01909 Nucleotidyltransferase domain 13 68 3.2E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1224 ffbf25a1cd5147790b4cdcef193a7823 125 SUPERFAMILY SSF81301 6 95 8.18E-16 T 23-10-2018 TSIB_1224 ffbf25a1cd5147790b4cdcef193a7823 125 Gene3D G3DSA:3.30.460.10 1 118 1.1E-13 T 23-10-2018 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 Gene3D G3DSA:3.40.50.1370 5 298 2.0E-122 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 290 1.1E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 1.1E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 133 144 1.1E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.1E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 3 304 39.815 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 SUPERFAMILY SSF53671 2 303 8.3E-101 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 Gene3D G3DSA:3.40.50.1370 133 289 2.0E-122 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 5 302 3.8E-129 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 283 297 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 222 231 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 132 149 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 78 87 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 2.6E-39 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 2.6E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSIB_0445 41f8c12c62903b096897469aaefd0f24 306 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 298 1.0E-30 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Pfam PF03129 Anticodon binding domain 296 391 4.5E-21 T 23-10-2018 IPR004154 Anticodon-binding TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 152 163 1.7E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 71 89 1.7E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 142 150 1.7E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 112 123 1.7E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 SUPERFAMILY SSF64586 413 488 4.12E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Gene3D G3DSA:3.30.930.10 18 289 4.3E-82 T 23-10-2018 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 SMART SM00946 418 488 5.7E-21 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 16 488 3.2E-175 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 SUPERFAMILY SSF55681 17 283 1.43E-72 T 23-10-2018 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 419 488 3.7E-14 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Gene3D G3DSA:3.40.50.800 290 408 1.8E-37 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 109 277 1.1E-21 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Gene3D G3DSA:3.30.110.30 412 487 1.1E-17 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 SUPERFAMILY SSF52954 285 410 1.96E-36 T 23-10-2018 TSIB_1015 aef52f05244bda1b0e7dc15f2b26971b 488 Hamap MF_01571 Proline--tRNA ligase [proS]. 12 488 40.515 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 SUPERFAMILY SSF51395 17 236 1.72E-46 T 23-10-2018 TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 20 234 1.1E-73 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 Gene3D G3DSA:3.20.20.390 3 254 2.0E-96 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 Pfam PF01884 PcrB family 15 237 2.6E-65 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 227 1.3E-80 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 TSIB_0683 bf1d471ab397875f28a87427b77bc22c 255 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 14 249 33.575 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TSIB_0230 2ba5b32ab938b15cf0563f176c41e127 282 SUPERFAMILY SSF51569 8 267 3.66E-69 T 23-10-2018 TSIB_0230 2ba5b32ab938b15cf0563f176c41e127 282 Pfam PF01791 DeoC/LacD family aldolase 24 252 3.2E-34 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_0230 2ba5b32ab938b15cf0563f176c41e127 282 SMART SM01133 23 252 1.2E-38 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_0230 2ba5b32ab938b15cf0563f176c41e127 282 PIRSF PIRSF038992 4 282 1.2E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_0230 2ba5b32ab938b15cf0563f176c41e127 282 Gene3D G3DSA:3.20.20.70 2 280 1.0E-82 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0839 f0bbe8a2e28a43350bb69981f4310688 201 PIRSF PIRSF019239 29 201 2.6E-46 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_0839 f0bbe8a2e28a43350bb69981f4310688 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 1.9E-37 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 419 597 1.3E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 313 1.4E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 Gene3D G3DSA:1.10.3720.10 19 320 2.5E-50 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 Gene3D G3DSA:1.10.3720.10 331 609 2.1E-37 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 SUPERFAMILY SSF161098 23 313 3.14E-43 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0221 b3c09ca530f610d0803792b57c9a6b5c 614 SUPERFAMILY SSF161098 335 607 1.22E-40 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 Gene3D G3DSA:3.40.50.620 1 132 1.3E-21 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 Gene3D G3DSA:3.40.50.620 136 265 1.0E-25 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 SUPERFAMILY SSF52402 14 124 1.26E-20 T 23-10-2018 TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 SUPERFAMILY SSF52402 138 263 4.19E-22 T 23-10-2018 TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 PRINTS PR01438 Universal stress protein signature 138 156 3.1E-15 T 23-10-2018 IPR006015 Universal stress protein A TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 PRINTS PR01438 Universal stress protein signature 241 263 3.1E-15 T 23-10-2018 IPR006015 Universal stress protein A TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 PRINTS PR01438 Universal stress protein signature 223 235 3.1E-15 T 23-10-2018 IPR006015 Universal stress protein A TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 Pfam PF00582 Universal stress protein family 17 118 5.1E-18 T 23-10-2018 IPR006016 UspA TSIB_0662 e38f22d7ad2bbbafade14041520fc6f9 265 Pfam PF00582 Universal stress protein family 139 263 2.9E-15 T 23-10-2018 IPR006016 UspA TSIB_0415 bbc8912d27e552fbde9a543f6b5d785f 378 SUPERFAMILY SSF53335 55 155 1.43E-18 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0415 bbc8912d27e552fbde9a543f6b5d785f 378 Gene3D G3DSA:3.40.50.150 37 230 3.2E-29 T 23-10-2018 TSIB_0415 bbc8912d27e552fbde9a543f6b5d785f 378 Pfam PF09445 RNA cap guanine-N2 methyltransferase 80 151 5.5E-11 T 23-10-2018 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253 TSIB_1816 3ed922dcaec84277f2cb5edee8e6b297 264 Pfam PF00795 Carbon-nitrogen hydrolase 3 243 1.8E-55 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSIB_1816 3ed922dcaec84277f2cb5edee8e6b297 264 Gene3D G3DSA:3.60.110.10 1 264 8.4E-100 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSIB_1816 3ed922dcaec84277f2cb5edee8e6b297 264 SUPERFAMILY SSF56317 1 262 6.15E-71 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 SUPERFAMILY SSF53448 1 278 1.24E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 251 280 8.6E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 Gene3D G3DSA:3.90.550.10 1 239 4.4E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 Pfam PF00483 Nucleotidyl transferase 3 234 9.2E-40 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 SUPERFAMILY SSF51161 242 311 2.52E-9 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_2017 9a58f2e6aa0a015988917bfa60018d1b 331 Gene3D G3DSA:2.160.10.10 240 330 1.9E-6 T 23-10-2018 TSIB_1273 40e44ae3b7c58947a325e080f4f7975a 298 Pfam PF00953 Glycosyl transferase family 4 67 213 5.4E-32 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TSIB_0804 f7997d51472fd018d9289c296eb3dfa8 179 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 11 173 2.1E-29 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 TSIB_0804 f7997d51472fd018d9289c296eb3dfa8 179 Pfam PF01381 Helix-turn-helix 93 144 1.3E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0804 f7997d51472fd018d9289c296eb3dfa8 179 Gene3D G3DSA:1.10.260.40 81 179 2.9E-15 T 23-10-2018 TSIB_0804 f7997d51472fd018d9289c296eb3dfa8 179 SUPERFAMILY SSF47413 82 147 2.06E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_0804 f7997d51472fd018d9289c296eb3dfa8 179 SMART SM00530 92 147 8.8E-10 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_1507 8c7efb6dd5b36bc7d8ace47f6cb1c308 189 Hamap MF_01842 Archaemetzincin [amzA]. 1 179 33.973 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TSIB_1507 8c7efb6dd5b36bc7d8ace47f6cb1c308 189 SUPERFAMILY SSF55486 23 176 8.86E-18 T 23-10-2018 TSIB_1507 8c7efb6dd5b36bc7d8ace47f6cb1c308 189 Pfam PF07998 Peptidase family M54 66 180 9.4E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TSIB_1507 8c7efb6dd5b36bc7d8ace47f6cb1c308 189 PIRSF PIRSF005785 2 187 2.7E-54 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TSIB_1507 8c7efb6dd5b36bc7d8ace47f6cb1c308 189 Gene3D G3DSA:3.40.390.10 6 184 1.1E-47 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TSIB_0316 df3b80b4ba0c9815f550649e9bffa4d5 193 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.159 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSIB_0316 df3b80b4ba0c9815f550649e9bffa4d5 193 Gene3D G3DSA:3.40.50.300 1 177 7.2E-44 T 23-10-2018 TSIB_0316 df3b80b4ba0c9815f550649e9bffa4d5 193 SUPERFAMILY SSF52540 7 175 1.63E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0316 df3b80b4ba0c9815f550649e9bffa4d5 193 Pfam PF13189 Cytidylate kinase-like family 7 158 8.2E-24 T 23-10-2018 TSIB_0316 df3b80b4ba0c9815f550649e9bffa4d5 193 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 2.1E-61 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSIB_0481 960cd6b456cf79656d9d57e790e92bba 217 Gene3D G3DSA:3.40.390.10 52 209 4.4E-21 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TSIB_0481 960cd6b456cf79656d9d57e790e92bba 217 Pfam PF07998 Peptidase family M54 1 210 8.5E-49 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TSIB_0481 960cd6b456cf79656d9d57e790e92bba 217 PIRSF PIRSF005785 1 217 1.5E-39 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TSIB_0481 960cd6b456cf79656d9d57e790e92bba 217 SUPERFAMILY SSF55486 159 192 1.42E-7 T 23-10-2018 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 Gene3D G3DSA:3.80.30.20 233 385 3.2E-14 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 SMART SM00729 83 375 4.3E-52 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 PIRSF PIRSF005669 1 574 1.3E-250 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 Pfam PF04055 Radical SAM superfamily 90 319 3.9E-29 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 17 573 3.0E-263 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 Pfam PF00583 Acetyltransferase (GNAT) family 450 562 5.0E-8 T 23-10-2018 IPR000182 GNAT domain TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 Gene3D G3DSA:3.40.630.30 422 574 4.2E-8 T 23-10-2018 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 Pfam PF16199 Radical_SAM C-terminal domain 336 415 7.5E-28 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 SUPERFAMILY SSF102114 86 382 1.07E-36 T 23-10-2018 TSIB_1807 05f967ee58e7efb77d914d8d58ffae1b 593 SUPERFAMILY SSF55729 447 569 2.75E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_1409 86a3b5d3ad92cbca836cefafaf9c028b 367 Gene3D G3DSA:3.40.50.2000 1 175 2.0E-42 T 23-10-2018 TSIB_1409 86a3b5d3ad92cbca836cefafaf9c028b 367 Pfam PF00534 Glycosyl transferases group 1 171 318 5.5E-28 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_1409 86a3b5d3ad92cbca836cefafaf9c028b 367 Pfam PF13439 Glycosyltransferase Family 4 14 169 3.3E-31 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSIB_1409 86a3b5d3ad92cbca836cefafaf9c028b 367 Gene3D G3DSA:3.40.50.2000 176 324 1.4E-32 T 23-10-2018 TSIB_1409 86a3b5d3ad92cbca836cefafaf9c028b 367 SUPERFAMILY SSF53756 3 344 1.15E-78 T 23-10-2018 TSIB_1900 15d901f757769636c00187abf83f85ce 152 Pfam PF00578 AhpC/TSA family 6 129 4.0E-34 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1900 15d901f757769636c00187abf83f85ce 152 PIRSF PIRSF000239 1 152 1.4E-22 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1900 15d901f757769636c00187abf83f85ce 152 SUPERFAMILY SSF52833 4 151 3.55E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1900 15d901f757769636c00187abf83f85ce 152 Gene3D G3DSA:3.40.30.10 1 151 2.0E-46 T 23-10-2018 TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.024 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 Gene3D G3DSA:3.30.2320.30 100 203 2.6E-20 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 SUPERFAMILY SSF160527 81 203 2.48E-25 T 23-10-2018 TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 SUPERFAMILY SSF81573 13 64 4.9E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 Gene3D G3DSA:1.20.5.620 18 97 6.0E-24 T 23-10-2018 TSIB_1795 c60976915d37475e861a0bddbd7f64e8 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 1.2E-37 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_2045 0a69d346838db7518f526a35bf1d5894 333 SUPERFAMILY SSF51735 1 320 2.88E-95 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_2045 0a69d346838db7518f526a35bf1d5894 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 4.5E-160 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TSIB_2045 0a69d346838db7518f526a35bf1d5894 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 1.3E-82 T 23-10-2018 IPR016040 NAD(P)-binding domain TSIB_2045 0a69d346838db7518f526a35bf1d5894 333 Gene3D G3DSA:3.40.50.720 4 294 6.0E-132 T 23-10-2018 TSIB_2045 0a69d346838db7518f526a35bf1d5894 333 Gene3D G3DSA:3.90.25.10 177 309 6.0E-132 T 23-10-2018 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 153 8.6E-33 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 SUPERFAMILY SSF53163 11 156 3.01E-30 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 TIGRFAM TIGR00142 hycI: hydrogenase maturation peptidase HycI 14 156 3.7E-36 T 23-10-2018 IPR004420 Peptidase A31, hydrogenase maturation protease HycI GO:0008233 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 Pfam PF01750 Hydrogenase maturation protease 30 151 2.9E-18 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 Gene3D G3DSA:3.40.50.1450 9 156 3.6E-43 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 PRINTS PR00446 Hydrogen uptake protein signature 25 36 3.6E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 PRINTS PR00446 Hydrogen uptake protein signature 13 25 3.6E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1002 ab4e279e0fa04688fd1a4b4cca5c5096 157 PRINTS PR00446 Hydrogen uptake protein signature 67 77 3.6E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSIB_1875 cf3778d21ac188da651391f422285b51 200 SUPERFAMILY SSF109755 2 199 5.23E-32 T 23-10-2018 TSIB_1875 cf3778d21ac188da651391f422285b51 200 Pfam PF01895 PhoU domain 116 187 1.5E-11 T 23-10-2018 IPR026022 PhoU domain TSIB_1875 cf3778d21ac188da651391f422285b51 200 Pfam PF01895 PhoU domain 17 96 4.9E-6 T 23-10-2018 IPR026022 PhoU domain TSIB_1875 cf3778d21ac188da651391f422285b51 200 Gene3D G3DSA:1.20.58.220 1 200 1.2E-31 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_0105 d4077e41066e6273666fedeeba589e13 267 Gene3D G3DSA:3.20.20.70 1 265 1.4E-62 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0105 d4077e41066e6273666fedeeba589e13 267 SUPERFAMILY SSF102114 1 260 2.75E-54 T 23-10-2018 TSIB_0105 d4077e41066e6273666fedeeba589e13 267 Pfam PF04055 Radical SAM superfamily 1 131 1.4E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0105 d4077e41066e6273666fedeeba589e13 267 Pfam PF06463 Molybdenum Cofactor Synthesis C 139 266 9.2E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSIB_0105 d4077e41066e6273666fedeeba589e13 267 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 1 267 3.0E-101 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 184 202 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 94 114 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 224 249 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 275 301 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 63 84 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 327 348 1.4E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 407 4.4E-167 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 SUPERFAMILY SSF55035 128 243 3.79E-40 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 31 407 4.7E-140 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 SUPERFAMILY SSF56542 4 397 3.79E-94 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 Gene3D G3DSA:1.10.3270.10 1 73 1.3E-8 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 339 346 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 186 200 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 Gene3D G3DSA:3.90.770.10 74 394 4.1E-133 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0612 83568b8e6217f8a4d3a92956c122be99 407 Gene3D G3DSA:3.30.70.420 128 243 4.1E-133 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSIB_0889 a924ea6df52358ca4503d35969d23f88 69 Gene3D G3DSA:4.10.1150.10 4 68 1.4E-14 T 23-10-2018 IPR024069 AF2212-like domain superfamily TSIB_0889 a924ea6df52358ca4503d35969d23f88 69 SUPERFAMILY SSF141694 5 66 1.2E-15 T 23-10-2018 TSIB_0889 a924ea6df52358ca4503d35969d23f88 69 Pfam PF01954 Protein of unknown function DUF104 5 63 3.5E-16 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TSIB_1075 caccadaa7a04dddab89ace6a8d112004 485 SUPERFAMILY SSF52402 148 376 3.4E-7 T 23-10-2018 TSIB_1075 caccadaa7a04dddab89ace6a8d112004 485 Gene3D G3DSA:3.40.50.620 147 369 9.5E-11 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1222 b2a0e5421b04043806f712653bbdca34 292 Pfam PF01875 Memo-like protein 5 288 3.1E-71 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TSIB_1222 b2a0e5421b04043806f712653bbdca34 292 Hamap MF_00055 MEMO1 family protein . 1 290 56.419 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TSIB_1222 b2a0e5421b04043806f712653bbdca34 292 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 288 1.1E-86 T 23-10-2018 TSIB_1222 b2a0e5421b04043806f712653bbdca34 292 Gene3D G3DSA:3.40.830.10 1 291 3.9E-66 T 23-10-2018 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 235 600 1.6E-112 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 11 210 1.5E-65 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 Gene3D G3DSA:1.10.569.10 243 433 7.2E-114 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 Gene3D G3DSA:3.60.9.10 5 215 2.9E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 SMART SM00790 9 211 4.2E-84 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 SUPERFAMILY SSF48310 215 600 1.57E-104 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 SUPERFAMILY SSF56228 7 213 7.06E-61 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1628 34d8b7865680ef6585e04245bc46697c 604 Gene3D G3DSA:1.10.599.10 241 600 7.2E-114 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_1375 e651f7ba07fc3bae2bd468f41c648e53 243 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 5 234 2.6E-73 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TSIB_1375 e651f7ba07fc3bae2bd468f41c648e53 243 PIRSF PIRSF019322 1 243 3.1E-90 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TSIB_0751 e96be922e641eeec5604e4925294d570 140 PIRSF PIRSF016702 1 139 8.9E-45 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif TSIB_0751 e96be922e641eeec5604e4925294d570 140 Gene3D G3DSA:3.30.1330.80 1 139 9.3E-49 T 23-10-2018 TSIB_0751 e96be922e641eeec5604e4925294d570 140 SUPERFAMILY SSF117856 4 129 8.37E-36 T 23-10-2018 TSIB_0751 e96be922e641eeec5604e4925294d570 140 Pfam PF03479 Domain of unknown function (DUF296) 7 118 1.6E-20 T 23-10-2018 IPR005175 PPC domain TSIB_1910 6871eed1a5c5fba28f2eb06cfffdc539 617 Pfam PF00361 Proton-conducting membrane transporter 116 423 3.9E-62 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 Gene3D G3DSA:3.40.1160.10 1 315 4.4E-138 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 SUPERFAMILY SSF53633 3 314 3.8E-86 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 TIGRFAM TIGR00746 arcC: carbamate kinase 3 314 2.7E-145 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 Pfam PF00696 Amino acid kinase family 3 296 1.5E-28 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PIRSF PIRSF000723 1 315 2.7E-141 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 78 96 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 113 132 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 215 230 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 270 285 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 185 203 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 162 181 9.9E-68 T 23-10-2018 TSIB_1834 36e499e4b7de3af1ffdd8c61bab9821e 315 PRINTS PR01469 Bacterial carbamate kinase signature 45 64 9.9E-68 T 23-10-2018 TSIB_0989 91819172edcdc93335849415e7f609b1 67 Gene3D G3DSA:3.30.70.20 2 66 6.2E-16 T 23-10-2018 TSIB_0989 91819172edcdc93335849415e7f609b1 67 SUPERFAMILY SSF54862 3 65 3.84E-18 T 23-10-2018 TSIB_0989 91819172edcdc93335849415e7f609b1 67 Pfam PF00037 4Fe-4S binding domain 7 30 2.1E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0989 91819172edcdc93335849415e7f609b1 67 Pfam PF00037 4Fe-4S binding domain 38 59 6.6E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0989 91819172edcdc93335849415e7f609b1 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0989 91819172edcdc93335849415e7f609b1 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 SUPERFAMILY SSF53901 175 348 1.99E-43 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 Gene3D G3DSA:3.40.47.10 8 348 2.8E-71 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 170 2.5E-4 T 23-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 303 4.9E-10 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 SUPERFAMILY SSF53901 10 169 4.45E-33 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 Hamap MF_01409 UPF0219 protein . 10 350 60.552 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TSIB_0799 c8d4f55a8dd10de8e11af5f2e089fbb4 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 10 349 6.1E-189 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TSIB_1341 57ce9bd4c1e2c8e5501295139dcead5b 133 Pfam PF01920 Prefoldin subunit 25 128 4.9E-22 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TSIB_1341 57ce9bd4c1e2c8e5501295139dcead5b 133 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 133 43.144 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TSIB_1341 57ce9bd4c1e2c8e5501295139dcead5b 133 SUPERFAMILY SSF46579 22 126 1.22E-21 T 23-10-2018 TSIB_1341 57ce9bd4c1e2c8e5501295139dcead5b 133 Gene3D G3DSA:1.10.287.370 17 133 1.4E-37 T 23-10-2018 IPR009053 Prefoldin TSIB_1341 57ce9bd4c1e2c8e5501295139dcead5b 133 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 20 128 2.2E-37 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TSIB_1584 c119ee21de9e44d0722986f0087a5711 258 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 15 232 30.627 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSIB_1584 c119ee21de9e44d0722986f0087a5711 258 Pfam PF02511 Thymidylate synthase complementing protein 21 212 2.3E-61 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSIB_1584 c119ee21de9e44d0722986f0087a5711 258 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 19 212 6.0E-52 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSIB_1584 c119ee21de9e44d0722986f0087a5711 258 Gene3D G3DSA:3.30.1360.170 8 216 1.3E-60 T 23-10-2018 TSIB_1584 c119ee21de9e44d0722986f0087a5711 258 SUPERFAMILY SSF69796 14 212 4.05E-60 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 Gene3D G3DSA:3.10.580.10 107 183 2.1E-14 T 23-10-2018 TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 SMART SM00116 55 102 2.8E-4 T 23-10-2018 IPR000644 CBS domain TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 SMART SM00116 133 181 1.8E-7 T 23-10-2018 IPR000644 CBS domain TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 SUPERFAMILY SSF54631 36 180 6.68E-29 T 23-10-2018 TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 Gene3D G3DSA:3.10.580.10 7 106 3.8E-14 T 23-10-2018 TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 Pfam PF00571 CBS domain 51 100 1.5E-12 T 23-10-2018 IPR000644 CBS domain TSIB_0452 1554506a74770d3f6534d8f1f3b20a8a 185 Pfam PF00571 CBS domain 126 180 2.2E-12 T 23-10-2018 IPR000644 CBS domain TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 Pfam PF03008 Archaea bacterial proteins of unknown function 309 408 1.7E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 Pfam PF01637 ATPase domain predominantly from Archaea 2 202 8.2E-35 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 Gene3D G3DSA:3.40.50.300 1 168 2.8E-34 T 23-10-2018 TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 Pfam PF01022 Bacterial regulatory protein, arsR family 244 283 8.0E-6 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 SUPERFAMILY SSF46785 240 319 1.63E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0965 aa0d54d661b552143e022f175b1993e9 460 SUPERFAMILY SSF52540 1 241 4.13E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0787 9cc3a4ff4ad1402cb0ee89f62ca9caaa 323 Pfam PF13847 Methyltransferase domain 160 276 6.2E-16 T 23-10-2018 IPR025714 Methyltransferase domain TSIB_0787 9cc3a4ff4ad1402cb0ee89f62ca9caaa 323 Gene3D G3DSA:3.40.50.150 143 311 1.8E-23 T 23-10-2018 TSIB_0787 9cc3a4ff4ad1402cb0ee89f62ca9caaa 323 SUPERFAMILY SSF53335 130 304 2.99E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1195 24f23261d50ed18089ef418fce5e3a7d 419 SUPERFAMILY SSF109604 3 414 1.09E-91 T 23-10-2018 TSIB_1195 24f23261d50ed18089ef418fce5e3a7d 419 Gene3D G3DSA:1.10.3210.10 6 293 1.4E-86 T 23-10-2018 TSIB_1195 24f23261d50ed18089ef418fce5e3a7d 419 Pfam PF01966 HD domain 55 123 2.0E-15 T 23-10-2018 IPR006674 HD domain TSIB_1195 24f23261d50ed18089ef418fce5e3a7d 419 SMART SM00471 51 191 4.8E-12 T 23-10-2018 IPR003607 HD/PDEase domain TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 Gene3D G3DSA:1.10.10.10 3 56 2.0E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.4E-18 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.4E-18 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.4E-18 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 SUPERFAMILY SSF46785 5 66 9.97E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 Pfam PF01037 Lrp/AsnC ligand binding domain 72 141 8.2E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 6.2E-19 T 23-10-2018 TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 SMART SM00344 6 112 2.3E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 SUPERFAMILY SSF54909 66 149 8.58E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_1429 963d3fdf761f76522b558bea3a629fe4 151 Gene3D G3DSA:3.30.70.920 58 149 3.8E-23 T 23-10-2018 TSIB_0011 cd59f64508aae4c15180dab10de2ebcb 339 Pfam PF14258 Domain of unknown function (DUF4350) 36 105 5.0E-10 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.2E-8 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 1.9E-31 T 23-10-2018 IPR001498 Impact, N-terminal TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 SUPERFAMILY SSF54211 4 132 2.12E-39 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 Gene3D G3DSA:3.30.230.30 1 132 4.8E-42 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 SUPERFAMILY SSF54980 137 199 1.01E-9 T 23-10-2018 IPR035647 EF-G domain III/V-like TSIB_1539 33e4fb93a089a176852e3cc34a9fd27e 203 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 11 200 1.2E-50 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal TSIB_1245 a648fbe39226c3bba5ec609aa7199ccd 288 Pfam PF01889 Membrane protein of unknown function DUF63 29 286 8.6E-75 T 23-10-2018 IPR002749 Protein of unknown function DUF63 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 Gene3D G3DSA:3.30.160.750 66 129 5.7E-25 T 23-10-2018 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 1.8E-45 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 SUPERFAMILY SSF56276 6 120 4.71E-41 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.745 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 5.4E-38 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSIB_1802 5e7b0c2838473f7508c9d659c7f7de76 141 Gene3D G3DSA:3.30.360.110 4 65 1.7E-20 T 23-10-2018 TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 500 37.749 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 SUPERFAMILY SSF46785 70 140 9.7E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 Gene3D G3DSA:1.10.10.10 3 77 8.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 Pfam PF01409 tRNA synthetases class II core domain (F) 226 498 1.6E-82 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 SUPERFAMILY SSF46785 14 80 7.89E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 192 500 7.2E-95 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 SUPERFAMILY SSF55681 227 500 9.79E-58 T 23-10-2018 TSIB_0616 4aa1d7eaaaef1d0c1502c44f6e88b03e 503 Gene3D G3DSA:3.30.930.10 196 503 1.1E-90 T 23-10-2018 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 285 1.7E-68 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 162 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 Gene3D G3DSA:3.20.20.70 1 289 5.5E-100 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 SMART SM01130 1 289 4.0E-102 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 9.7E-70 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 3.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 3.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 3.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 3.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 PIRSF PIRSF001365 1 291 3.9E-83 T 23-10-2018 IPR002220 DapA-like GO:0016829 TSIB_1436 14e9b901b105bc39b99d3d66867f9b92 291 SUPERFAMILY SSF51569 3 290 3.45E-89 T 23-10-2018 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 120 7.5E-30 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 150 315 1.8E-28 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 1 329 3.5E-130 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 SUPERFAMILY SSF51735 1 167 1.0E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 SMART SM00859 2 122 5.4E-30 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 PIRSF PIRSF000148 1 334 2.8E-90 T 23-10-2018 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 SUPERFAMILY SSF55347 139 317 1.52E-39 T 23-10-2018 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 Gene3D G3DSA:3.30.360.10 141 312 1.8E-122 T 23-10-2018 TSIB_1599 9937e1bb9fbca9bfdc2bbddafb7d80fe 335 Gene3D G3DSA:3.40.50.720 3 328 1.8E-122 T 23-10-2018 TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 Gene3D G3DSA:3.40.50.720 1 240 3.3E-78 T 23-10-2018 TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.7E-42 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 SUPERFAMILY SSF51735 4 241 5.82E-74 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.9E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.9E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_1998 d596693b2c9a11bc04c11107af114bdb 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 238 6.8E-56 T 23-10-2018 TSIB_2021 5c863663a61bbc439428364888720eb9 386 Pfam PF00534 Glycosyl transferases group 1 200 362 5.8E-37 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_2021 5c863663a61bbc439428364888720eb9 386 Gene3D G3DSA:3.40.50.2000 21 375 1.4E-77 T 23-10-2018 TSIB_2021 5c863663a61bbc439428364888720eb9 386 SUPERFAMILY SSF53756 21 383 2.46E-86 T 23-10-2018 TSIB_2021 5c863663a61bbc439428364888720eb9 386 Pfam PF13439 Glycosyltransferase Family 4 22 187 2.6E-21 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSIB_2021 5c863663a61bbc439428364888720eb9 386 Gene3D G3DSA:3.40.50.2000 186 365 1.4E-77 T 23-10-2018 TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 212 3.9E-23 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 Gene3D G3DSA:3.40.50.300 2 233 8.2E-64 T 23-10-2018 TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 251 1.6E-113 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 PIRSF PIRSF003092 1 260 4.8E-63 T 23-10-2018 IPR025501 ATP binding protein MinD TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 SUPERFAMILY SSF52540 3 236 5.22E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0678 884a482e8d7731df357b5049343fcfc3 260 SMART SM00382 2 163 0.0089 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 318 1.4E-30 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 SUPERFAMILY SSF51735 100 287 1.11E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 Gene3D G3DSA:3.40.50.720 14 318 2.1E-106 T 23-10-2018 TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 1.7E-51 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 Gene3D G3DSA:3.40.50.720 95 286 2.1E-106 T 23-10-2018 TSIB_1016 1eb385ab19db2c65ea65d341cc385169 333 SUPERFAMILY SSF52283 1 132 1.64E-32 T 23-10-2018 TSIB_1149 e50fdd00593fef9253ac8350d904c719 200 Gene3D G3DSA:1.10.1760.20 34 195 5.5E-48 T 23-10-2018 TSIB_1149 e50fdd00593fef9253ac8350d904c719 200 Pfam PF07155 ECF-type riboflavin transporter, S component 39 185 7.6E-39 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 2.9E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 PRINTS PR00377 Inositol monophosphatase superfamily signature 163 184 2.9E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 2.9E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 220 2.9E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 2.9E-25 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 Pfam PF00459 Inositol monophosphatase family 6 248 4.2E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 Gene3D G3DSA:3.30.540.10 1 138 1.4E-32 T 23-10-2018 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 23-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 Gene3D G3DSA:3.40.190.80 143 251 5.2E-30 T 23-10-2018 TSIB_0724 4387ee66eb353d260b19fa9da108007d 251 SUPERFAMILY SSF56655 3 247 1.16E-52 T 23-10-2018 TSIB_2041 0311133435a15d22cbc54e3bd14a9df7 393 SUPERFAMILY SSF75712 272 337 3.01E-9 T 23-10-2018 TSIB_2041 0311133435a15d22cbc54e3bd14a9df7 393 Pfam PF01385 Probable transposase 167 259 3.9E-8 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_2041 0311133435a15d22cbc54e3bd14a9df7 393 Pfam PF07282 Putative transposase DNA-binding domain 290 357 3.6E-25 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_2041 0311133435a15d22cbc54e3bd14a9df7 393 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 5.2E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1906 2b32f777fa24ab5bb5848a57a827c4fd 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 2.8E-69 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1906 2b32f777fa24ab5bb5848a57a827c4fd 391 Gene3D G3DSA:1.10.645.20 27 391 1.4E-110 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1906 2b32f777fa24ab5bb5848a57a827c4fd 391 SUPERFAMILY SSF56762 39 391 3.14E-90 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1906 2b32f777fa24ab5bb5848a57a827c4fd 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0756 af2e577ffa456604ae247d3413cbf3d0 299 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 12 289 2.2E-55 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 TSIB_0756 af2e577ffa456604ae247d3413cbf3d0 299 Gene3D G3DSA:1.10.4200.10 28 296 4.4E-62 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 SUPERFAMILY SSF118215 17 419 1.96E-119 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 47 62 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TSIB_0228 0776f948594f56a77df6957a69970ccb 428 Gene3D G3DSA:1.10.3860.10 5 428 8.4E-163 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 55 75 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 PRINTS PR00173 Glutamate-aspartate symporter signature 366 386 2.1E-49 T 23-10-2018 TSIB_0228 0776f948594f56a77df6957a69970ccb 428 Pfam PF00375 Sodium:dicarboxylate symporter family 17 418 6.3E-125 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TSIB_0284 7979d9f73e56b353fc4c71a5b615f845 267 Gene3D G3DSA:3.40.50.700 9 169 2.7E-41 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TSIB_0284 7979d9f73e56b353fc4c71a5b615f845 267 SUPERFAMILY SSF56770 10 217 1.22E-46 T 23-10-2018 TSIB_0284 7979d9f73e56b353fc4c71a5b615f845 267 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 21 156 9.0E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0887 10c1784ab131b63deaf06fc6fae019ee 191 PIRSF PIRSF014735 2 178 2.7E-67 T 23-10-2018 IPR028300 Holliday junction resolvase-related TSIB_0887 10c1784ab131b63deaf06fc6fae019ee 191 Pfam PF10107 Endonuclease related to archaeal Holliday junction resolvase 11 168 3.7E-64 T 23-10-2018 IPR019287 Holliday junction resolvase-related domain TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 SUPERFAMILY SSF50104 5 115 5.59E-39 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 Pfam PF00467 KOW motif 49 79 1.6E-10 T 23-10-2018 IPR005824 KOW TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 SMART SM00739 45 72 9.3E-7 T 23-10-2018 IPR005824 KOW TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 5.4E-36 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.259 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 Gene3D G3DSA:2.30.30.30 1 120 2.2E-53 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_0300 1780d4442a9144ca963f89558bdb8736 120 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 5 120 5.0E-58 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1762 016e4726dc3bc4f59338015ce53e9d07 135 PIRSF PIRSF005264 1 135 6.5E-43 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TSIB_1762 016e4726dc3bc4f59338015ce53e9d07 135 Hamap MF_00585 UPF0216 protein . 4 135 27.029 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TSIB_1762 016e4726dc3bc4f59338015ce53e9d07 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 2.0E-34 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TSIB_1762 016e4726dc3bc4f59338015ce53e9d07 135 Pfam PF01886 Protein of unknown function DUF61 6 132 6.7E-38 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 Gene3D G3DSA:1.10.10.10 285 361 8.6E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 SUPERFAMILY SSF46785 284 359 1.81E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 SUPERFAMILY SSF52540 1 281 5.1E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 Gene3D G3DSA:3.40.50.300 1 205 2.5E-36 T 23-10-2018 TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 Pfam PF01637 ATPase domain predominantly from Archaea 19 247 3.0E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_1616 852138ba8420da7a73035dce7bb1e8e6 362 Gene3D G3DSA:1.10.8.60 207 284 4.6E-25 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 553 1.1E-179 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Gene3D G3DSA:1.10.730.10 345 586 3.0E-103 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 564 42.608 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 SUPERFAMILY SSF50249 632 731 2.08E-35 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Pfam PF08264 Anticodon-binding domain of tRNA 434 541 1.0E-13 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Gene3D G3DSA:2.170.220.10 102 256 1.3E-141 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Gene3D G3DSA:2.40.50.140 626 732 1.0E-42 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Pfam PF01588 Putative tRNA binding domain 638 729 5.0E-31 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 298 313 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 256 267 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 400 411 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 91 102 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 PRINTS PR01041 Methionyl-tRNA synthetase signature 43 57 8.9E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Gene3D G3DSA:3.40.50.620 10 320 1.3E-141 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 SUPERFAMILY SSF52374 7 398 8.0E-105 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 SUPERFAMILY SSF47323 402 644 6.73E-48 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Pfam PF09334 tRNA synthetases class I (M) 9 412 5.4E-159 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 609 732 5.5E-37 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 Gene3D G3DSA:1.10.730.10 402 552 3.0E-103 T 23-10-2018 TSIB_0133 f9c38096344288e162869ef2f1914a2b 732 SUPERFAMILY SSF57770 143 177 3.4E-11 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSIB_1371 eb463a102a2273e0b8018b2eba83ea12 329 Pfam PF00005 ABC transporter 39 182 2.4E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1371 eb463a102a2273e0b8018b2eba83ea12 329 Gene3D G3DSA:3.40.50.300 3 256 6.8E-68 T 23-10-2018 TSIB_1371 eb463a102a2273e0b8018b2eba83ea12 329 SUPERFAMILY SSF52540 10 244 5.95E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1371 eb463a102a2273e0b8018b2eba83ea12 329 SMART SM00382 47 240 4.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1371 eb463a102a2273e0b8018b2eba83ea12 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 35 324 3.1E-98 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TSIB_1714 11d3bdc90421302b5309f05b9f87c021 124 Pfam PF03625 Domain of unknown function DUF302 48 87 7.1E-5 T 23-10-2018 IPR005180 Domain of unknown function DUF302 TSIB_1714 11d3bdc90421302b5309f05b9f87c021 124 Gene3D G3DSA:3.30.310.70 4 124 2.6E-9 T 23-10-2018 IPR035923 TT1751-like domain superfamily TSIB_1714 11d3bdc90421302b5309f05b9f87c021 124 SUPERFAMILY SSF103247 2 123 1.83E-16 T 23-10-2018 IPR035923 TT1751-like domain superfamily TSIB_2049 a526ea8b76bfb9afa71680bdd20a5ea8 473 Pfam PF01943 Polysaccharide biosynthesis protein 8 276 7.0E-42 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TSIB_2049 a526ea8b76bfb9afa71680bdd20a5ea8 473 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 328 455 3.1E-16 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TSIB_0062 e71b2409ddd3bba1b6f9f9634145f73f 414 SUPERFAMILY SSF52540 17 146 9.46E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 SUPERFAMILY SSF55186 92 238 7.98E-37 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Pfam PF02272 DHHA1 domain 278 401 1.1E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 SUPERFAMILY SSF50447 1 90 4.24E-15 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Gene3D G3DSA:3.30.980.10 92 247 1.5E-40 T 23-10-2018 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Pfam PF01411 tRNA synthetases class II (A) 25 94 3.1E-12 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Gene3D G3DSA:2.40.30.130 1 91 6.1E-21 T 23-10-2018 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 SMART SM00863 191 234 1.9E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 1.0E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSIB_1789 0b4a50dce4ae0b48412a5b35daea57d2 409 Gene3D G3DSA:3.10.310.40 302 406 1.5E-8 T 23-10-2018 TSIB_0956 ea393d20477e84c6fbce1bba0d012991 218 SUPERFAMILY SSF56300 1 211 4.45E-70 T 23-10-2018 TSIB_0956 ea393d20477e84c6fbce1bba0d012991 218 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 194 6.3E-16 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TSIB_0956 ea393d20477e84c6fbce1bba0d012991 218 Gene3D G3DSA:3.60.21.10 1 214 7.6E-45 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0956 ea393d20477e84c6fbce1bba0d012991 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 205 2.3E-24 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSIB_1295 f6be2295e9959c7f24fa1f88f183865f 167 PIRSF PIRSF019239 1 166 8.7E-36 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_1295 f6be2295e9959c7f24fa1f88f183865f 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 165 4.7E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_1406 8a4b5f8f51dd51f5d5465f5a03e7b744 237 Pfam PF13614 AAA domain 3 155 7.3E-25 T 23-10-2018 IPR025669 AAA domain TSIB_1406 8a4b5f8f51dd51f5d5465f5a03e7b744 237 SUPERFAMILY SSF52540 1 234 7.25E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1406 8a4b5f8f51dd51f5d5465f5a03e7b744 237 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 233 3.8E-88 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TSIB_1406 8a4b5f8f51dd51f5d5465f5a03e7b744 237 PIRSF PIRSF003092 1 237 3.7E-54 T 23-10-2018 IPR025501 ATP binding protein MinD TSIB_1406 8a4b5f8f51dd51f5d5465f5a03e7b744 237 Gene3D G3DSA:3.40.50.300 1 235 1.2E-70 T 23-10-2018 TSIB_1734 cbd647d55876bc26a3bcb0b79a35321c 272 SUPERFAMILY SSF100950 12 121 1.47E-7 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TSIB_1734 cbd647d55876bc26a3bcb0b79a35321c 272 Gene3D G3DSA:3.40.50.1360 12 122 2.6E-5 T 23-10-2018 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 Gene3D G3DSA:3.10.310.70 87 193 2.5E-169 T 23-10-2018 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 Gene3D G3DSA:3.20.20.140 69 473 2.5E-169 T 23-10-2018 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 70 78 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 SUPERFAMILY SSF51338 13 512 1.52E-11 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 Pfam PF07969 Amidohydrolase family 57 511 7.5E-113 T 23-10-2018 IPR013108 Amidohydrolase 3 TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 SUPERFAMILY SSF51556 68 474 3.52E-41 T 23-10-2018 IPR032466 Metal-dependent hydrolase TSIB_0408 05c32ca1ff73fb7773e230b5fe0424c0 514 Gene3D G3DSA:2.30.40.10 14 491 2.5E-169 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSIB_0366 4afff0ed52c1142794ceabff8fc231e5 329 PIRSF PIRSF016202 3 329 3.2E-106 T 23-10-2018 IPR007184 Mannoside phosphorylase TSIB_0366 4afff0ed52c1142794ceabff8fc231e5 329 Gene3D G3DSA:2.115.10.20 20 328 5.7E-102 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSIB_0366 4afff0ed52c1142794ceabff8fc231e5 329 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 33 327 1.9E-92 T 23-10-2018 IPR007184 Mannoside phosphorylase TSIB_0366 4afff0ed52c1142794ceabff8fc231e5 329 SUPERFAMILY SSF75005 34 326 3.02E-69 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSIB_1230 b1217c8fe569428c9ce8809a325b3bc9 260 Pfam PF00696 Amino acid kinase family 1 233 2.0E-46 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSIB_1230 b1217c8fe569428c9ce8809a325b3bc9 260 SUPERFAMILY SSF53633 1 257 6.15E-42 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1230 b1217c8fe569428c9ce8809a325b3bc9 260 PIRSF PIRSF016496 1 259 4.2E-83 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 TSIB_1230 b1217c8fe569428c9ce8809a325b3bc9 260 Gene3D G3DSA:3.40.1160.10 1 258 3.5E-70 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 601 2.3E-243 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Pfam PF13522 Glutamine amidotransferase domain 65 192 2.8E-21 T 23-10-2018 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Gene3D G3DSA:3.60.20.10 2 240 5.8E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 SUPERFAMILY SSF56235 2 228 2.14E-72 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 601 40.206 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 SUPERFAMILY SSF53697 246 601 2.32E-110 T 23-10-2018 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Gene3D G3DSA:3.40.50.10490 441 586 2.2E-136 T 23-10-2018 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Gene3D G3DSA:3.40.50.10490 249 600 2.2E-136 T 23-10-2018 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Pfam PF01380 SIS domain 283 412 7.4E-30 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSIB_0417 669e5b21c618284e6685f9e3f72b7b12 601 Pfam PF01380 SIS domain 456 583 2.3E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSIB_1931 c48086629df6936974f904d6de4edd3b 142 SUPERFAMILY SSF88723 10 139 2.16E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_1931 c48086629df6936974f904d6de4edd3b 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 10 141 9.979 T 23-10-2018 IPR022907 VapC family GO:0004540 TSIB_1931 c48086629df6936974f904d6de4edd3b 142 Gene3D G3DSA:3.40.50.1010 10 141 1.3E-30 T 23-10-2018 TSIB_1931 c48086629df6936974f904d6de4edd3b 142 Pfam PF01850 PIN domain 10 138 1.1E-14 T 23-10-2018 IPR002716 PIN domain TSIB_1147 96d360edc12f1d0a8301f5b681b36277 308 Pfam PF01699 Sodium/calcium exchanger protein 167 307 5.0E-27 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TSIB_1147 96d360edc12f1d0a8301f5b681b36277 308 Pfam PF01699 Sodium/calcium exchanger protein 9 147 2.4E-21 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TSIB_1147 96d360edc12f1d0a8301f5b681b36277 308 Gene3D G3DSA:1.20.58.1130 12 198 3.4E-77 T 23-10-2018 TSIB_1147 96d360edc12f1d0a8301f5b681b36277 308 Gene3D G3DSA:1.20.1420.30 39 299 3.4E-77 T 23-10-2018 TSIB_1147 96d360edc12f1d0a8301f5b681b36277 308 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 7 299 1.3E-59 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 Gene3D G3DSA:2.30.30.100 200 247 3.1E-15 T 23-10-2018 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 Pfam PF02237 Biotin protein ligase C terminal domain 203 246 9.5E-12 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 12 246 9.0E-60 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 Pfam PF03099 Biotin/lipoate A/B protein ligase family 16 138 1.7E-19 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 SUPERFAMILY SSF50037 202 246 1.28E-8 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 SUPERFAMILY SSF55681 3 197 9.94E-54 T 23-10-2018 TSIB_0229 d7e091bd0cdc8c2ca20b6a311a5e2694 248 Gene3D G3DSA:3.30.930.10 1 199 4.9E-60 T 23-10-2018 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 123 152 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 23 42 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 204 225 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 73 94 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 98 115 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 153 182 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PRINTS PR00052 Fibrillarin signature 46 65 4.4E-77 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 Pfam PF01269 Fibrillarin 4 224 5.8E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.153 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 Gene3D G3DSA:3.30.200.20 1 50 8.2E-26 T 23-10-2018 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 SUPERFAMILY SSF53335 3 225 6.76E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 Gene3D G3DSA:3.40.50.150 51 226 2.9E-74 T 23-10-2018 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 PIRSF PIRSF006540 1 226 3.1E-100 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 TSIB_0797 d88c45b3c49f606b19c1860248066aed 226 SMART SM01206 3 226 1.7E-145 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.8E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.8E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.8E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.8E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.8E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 Pfam PF02254 TrkA-N domain 3 124 2.7E-31 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 Gene3D G3DSA:3.30.70.1450 141 222 7.5E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 Pfam PF02080 TrkA-C domain 156 221 9.6E-9 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 SUPERFAMILY SSF116726 136 220 3.01E-9 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 SUPERFAMILY SSF51735 1 145 6.2E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1799 6548afbf6db3ecbe71386157aa67f349 231 Gene3D G3DSA:3.40.50.720 1 140 7.5E-43 T 23-10-2018 TSIB_1240 90026c6c823c02b9a09a4aec83910a78 232 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 41.101 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSIB_1240 90026c6c823c02b9a09a4aec83910a78 232 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 2.2E-50 T 23-10-2018 TSIB_1240 90026c6c823c02b9a09a4aec83910a78 232 SUPERFAMILY SSF53271 14 217 2.75E-56 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_1240 90026c6c823c02b9a09a4aec83910a78 232 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 16 218 3.1E-73 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSIB_1240 90026c6c823c02b9a09a4aec83910a78 232 Gene3D G3DSA:3.40.50.2020 1 218 1.6E-60 T 23-10-2018 TSIB_0457 2c7845b4136a954454c163833b1b47b6 230 SUPERFAMILY SSF56784 3 223 2.53E-36 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0457 2c7845b4136a954454c163833b1b47b6 230 Gene3D G3DSA:3.40.50.1000 3 217 6.1E-38 T 23-10-2018 IPR023214 HAD superfamily TSIB_0457 2c7845b4136a954454c163833b1b47b6 230 Gene3D G3DSA:1.10.150.520 14 96 6.1E-38 T 23-10-2018 TSIB_0457 2c7845b4136a954454c163833b1b47b6 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 2.7E-23 T 23-10-2018 TSIB_0457 2c7845b4136a954454c163833b1b47b6 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 189 1.3E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_1841 df7b5a16c8d9b7e9db6b3e7c0d578520 339 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 1.9E-53 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TSIB_1841 df7b5a16c8d9b7e9db6b3e7c0d578520 339 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 335 4.6E-60 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 Pfam PF03167 Uracil DNA glycosylase superfamily 32 185 1.2E-44 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 SUPERFAMILY SSF52141 4 192 5.23E-59 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 Gene3D G3DSA:3.40.470.10 5 192 2.1E-68 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 18 192 4.7E-76 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 SMART SM00986 32 186 1.8E-35 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSIB_0879 25ab515bfe4b2360c5768a1b6047c9c3 194 SMART SM00987 32 186 1.8E-35 T 23-10-2018 TSIB_1620 0adb90cffc62971c256d277d2231b6a2 170 SUPERFAMILY SSF53335 5 145 4.46E-13 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1620 0adb90cffc62971c256d277d2231b6a2 170 Pfam PF13578 Methyltransferase domain 23 134 1.7E-11 T 23-10-2018 TSIB_1620 0adb90cffc62971c256d277d2231b6a2 170 Gene3D G3DSA:3.40.50.150 5 164 1.7E-16 T 23-10-2018 TSIB_0440 c666f899e21e95928ccba9850304a790 250 SMART SM00934 16 240 6.0E-37 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0440 c666f899e21e95928ccba9850304a790 250 Gene3D G3DSA:3.20.20.70 1 248 4.0E-80 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0440 c666f899e21e95928ccba9850304a790 250 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 239 8.6E-26 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0440 c666f899e21e95928ccba9850304a790 250 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 86 99 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0440 c666f899e21e95928ccba9850304a790 250 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 2 237 2.6E-60 T 23-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSIB_0440 c666f899e21e95928ccba9850304a790 250 SUPERFAMILY SSF51366 1 247 1.48E-62 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSIB_1381 7e2bad048d0212f4552b893f57623a88 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 64 218 3.0E-18 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1381 7e2bad048d0212f4552b893f57623a88 311 Gene3D G3DSA:3.40.50.970 101 310 2.1E-68 T 23-10-2018 TSIB_1381 7e2bad048d0212f4552b893f57623a88 311 Gene3D G3DSA:3.40.50.970 11 100 9.6E-6 T 23-10-2018 TSIB_1381 7e2bad048d0212f4552b893f57623a88 311 SUPERFAMILY SSF52518 16 309 3.24E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SMART SM00493 640 793 1.8E-42 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SMART SM00487 81 330 8.1E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SUPERFAMILY SSF52540 26 241 3.66E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Pfam PF01131 DNA topoisomerase 818 1202 1.5E-80 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SUPERFAMILY SSF56712 635 1212 1.28E-140 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Pfam PF00270 DEAD/DEAH box helicase 88 222 1.2E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Hamap MF_01125 Reverse gyrase [rgy]. 1 1213 63.812 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:1.10.290.10 919 1043 1.3E-140 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:3.40.50.300 542 626 4.3E-15 T 23-10-2018 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:3.40.50.300 319 496 1.0E-31 T 23-10-2018 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SMART SM00436 794 882 3.0E-41 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:3.40.50.140 628 817 5.4E-29 T 23-10-2018 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 767 780 1.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1032 1048 1.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1126 1140 1.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 951 960 1.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 853 871 1.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Pfam PF01751 Toprim domain 642 803 1.1E-25 T 23-10-2018 IPR006171 TOPRIM domain TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SUPERFAMILY SSF52540 325 622 1.89E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0530 41d8e2936cbd7082198192751b971793 1214 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1211 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:2.60.510.20 875 1110 1.3E-140 T 23-10-2018 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 SMART SM00437 909 1165 6.7E-95 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TSIB_0530 41d8e2936cbd7082198192751b971793 1214 Gene3D G3DSA:1.10.460.10 823 1206 1.3E-140 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TSIB_1935 4ad77d84959506665908926509d26e07 435 Pfam PF01385 Probable transposase 173 298 3.5E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_1935 4ad77d84959506665908926509d26e07 435 Pfam PF07282 Putative transposase DNA-binding domain 318 387 5.3E-22 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1935 4ad77d84959506665908926509d26e07 435 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 345 1.4E-9 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 Gene3D G3DSA:3.30.428.10 33 152 5.8E-90 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 Gene3D G3DSA:3.30.428.10 5 311 5.8E-90 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 165 316 1.1E-17 T 23-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 PIRSF PIRSF000808 1 316 3.4E-108 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 SUPERFAMILY SSF54197 156 317 3.56E-40 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 4 153 2.6E-24 T 23-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 7 312 1.5E-50 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSIB_0579 0e1b3d5419a4de9f5585ae493c565f88 328 SUPERFAMILY SSF54197 3 153 7.02E-46 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 22 386 2.0E-147 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Pfam PF09079 CDC6, C terminal winged helix domain 315 394 7.1E-25 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 SUPERFAMILY SSF52540 22 294 1.97E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Gene3D G3DSA:3.40.50.300 38 219 8.8E-107 T 23-10-2018 TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 SMART SM01074 315 396 2.0E-35 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 SMART SM00382 60 221 3.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 SUPERFAMILY SSF46785 300 405 2.45E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Hamap MF_01407 ORC1-type DNA replication protein. 15 397 33.922 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Gene3D G3DSA:1.10.8.60 22 298 8.8E-107 T 23-10-2018 TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Pfam PF13191 AAA ATPase domain 38 178 1.4E-8 T 23-10-2018 TSIB_1590 16909c7f2621a254eb32b0e816eaed6b 420 Gene3D G3DSA:1.10.10.10 307 406 1.2E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0185 53413b572f41741f0408053ca34e44b6 151 SUPERFAMILY SSF52218 1 150 1.63E-23 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_0185 53413b572f41741f0408053ca34e44b6 151 Gene3D G3DSA:3.40.50.360 3 148 1.8E-17 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_0185 53413b572f41741f0408053ca34e44b6 151 Pfam PF12724 Flavodoxin domain 4 85 2.5E-9 T 23-10-2018 IPR026816 Flavodoxin domain TSIB_1318 cf5af6c723a211ec4de4dec97a7ace97 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 20 81 5.0E-4 T 23-10-2018 TSIB_1281 61e55eef5d060a32295ea6fa6dde71c2 239 SUPERFAMILY SSF117396 1 237 3.27E-46 T 23-10-2018 IPR036520 UPF0759 superfamily TSIB_1281 61e55eef5d060a32295ea6fa6dde71c2 239 Gene3D G3DSA:3.20.20.410 1 238 7.1E-41 T 23-10-2018 IPR036520 UPF0759 superfamily TSIB_1281 61e55eef5d060a32295ea6fa6dde71c2 239 Pfam PF01904 Protein of unknown function DUF72 15 233 1.8E-37 T 23-10-2018 IPR002763 Protein of unknown function DUF72 TSIB_1754 5e5e75223ffe9fa8857b6b1cf4ea649f 349 SUPERFAMILY SSF161098 119 324 1.31E-13 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1754 5e5e75223ffe9fa8857b6b1cf4ea649f 349 Gene3D G3DSA:1.10.3720.10 111 337 8.1E-16 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1754 5e5e75223ffe9fa8857b6b1cf4ea649f 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 139 342 1.5E-37 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0021 3231e65e963d6feaf59a3ed63a2a3d6c 436 Pfam PF13173 AAA domain 54 175 4.7E-23 T 23-10-2018 TSIB_0021 3231e65e963d6feaf59a3ed63a2a3d6c 436 SUPERFAMILY SSF52540 35 241 1.48E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0333 8d28588a0c10acd73e7f514bcbc82e18 272 SMART SM00382 37 233 6.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0333 8d28588a0c10acd73e7f514bcbc82e18 272 Gene3D G3DSA:3.40.50.300 4 271 7.0E-71 T 23-10-2018 TSIB_0333 8d28588a0c10acd73e7f514bcbc82e18 272 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 1.1E-6 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_0333 8d28588a0c10acd73e7f514bcbc82e18 272 SUPERFAMILY SSF52540 5 267 8.67E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0333 8d28588a0c10acd73e7f514bcbc82e18 272 Pfam PF00005 ABC transporter 28 183 3.7E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1924 6c4ceff0b44753c328a23a51e9c8fc95 96 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 59 2.7E-6 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 TSIB_1924 6c4ceff0b44753c328a23a51e9c8fc95 96 SUPERFAMILY SSF82649 6 85 1.15E-9 T 23-10-2018 TSIB_1924 6c4ceff0b44753c328a23a51e9c8fc95 96 Gene3D G3DSA:3.30.390.50 1 87 1.9E-24 T 23-10-2018 TSIB_2039 14a2ec4f67a097ecca594dedd2287524 262 Pfam PF09407 AbiEi antitoxin C-terminal domain 87 204 2.5E-6 T 23-10-2018 IPR018547 AbiEi antitoxin C-terminal domain TSIB_2039 14a2ec4f67a097ecca594dedd2287524 262 SUPERFAMILY SSF46785 4 89 3.14E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0114 f2626423ade146868428c70249b28560 170 Gene3D G3DSA:3.40.50.1000 1 166 7.0E-26 T 23-10-2018 IPR023214 HAD superfamily TSIB_0114 f2626423ade146868428c70249b28560 170 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 130 4.0E-17 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC TSIB_0114 f2626423ade146868428c70249b28560 170 Pfam PF12689 Acid Phosphatase 1 141 4.9E-10 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 TSIB_0114 f2626423ade146868428c70249b28560 170 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 152 5.0E-30 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 TSIB_0114 f2626423ade146868428c70249b28560 170 SUPERFAMILY SSF56784 2 124 2.4E-17 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0462 9c76c61da528efd386361d62e655783e 446 Gene3D G3DSA:3.40.225.10 268 446 8.4E-70 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0462 9c76c61da528efd386361d62e655783e 446 Gene3D G3DSA:3.40.1190.20 1 267 5.1E-98 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0462 9c76c61da528efd386361d62e655783e 446 SUPERFAMILY SSF53639 265 444 4.71E-63 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0462 9c76c61da528efd386361d62e655783e 446 SUPERFAMILY SSF53613 4 259 5.3E-78 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0462 9c76c61da528efd386361d62e655783e 446 Pfam PF10120 Thiamine-phosphate synthase 273 442 5.6E-60 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0462 9c76c61da528efd386361d62e655783e 446 Pfam PF08543 Phosphomethylpyrimidine kinase 12 255 5.0E-94 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TSIB_0462 9c76c61da528efd386361d62e655783e 446 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 256 4.6E-103 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0712 1a9d5737b51f5431e2b0444d3b197e3d 356 SUPERFAMILY SSF52540 29 170 7.8E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0712 1a9d5737b51f5431e2b0444d3b197e3d 356 SMART SM00382 26 186 0.0042 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0712 1a9d5737b51f5431e2b0444d3b197e3d 356 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 210 6.2E-42 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TSIB_0712 1a9d5737b51f5431e2b0444d3b197e3d 356 Gene3D G3DSA:3.40.50.300 9 215 1.1E-28 T 23-10-2018 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Gene3D G3DSA:2.10.240.10 246 280 2.8E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 279 3.0E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PIRSF PIRSF006816 2 288 3.8E-84 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 SUPERFAMILY SSF63380 4 101 6.27E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Gene3D G3DSA:3.40.50.80 102 245 3.1E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Pfam PF00175 Oxidoreductase NAD-binding domain 113 226 3.4E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 112 131 4.4E-8 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 4.4E-8 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 149 160 4.4E-8 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 221 4.4E-8 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 SUPERFAMILY SSF52343 96 279 2.23E-30 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Pfam PF00970 Oxidoreductase FAD-binding domain 11 99 4.4E-9 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 Gene3D G3DSA:2.40.30.10 1 100 6.2E-20 T 23-10-2018 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 38 50 1.6E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 1.6E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 146 1.6E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_1521 40e485aa4e580650ee2cf353976c32ee 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 112 131 1.6E-11 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSIB_1625 fe209ff58bde689cd7dfdf5ce9794fac 272 Gene3D G3DSA:3.50.30.50 6 271 2.0E-70 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_1625 fe209ff58bde689cd7dfdf5ce9794fac 272 SUPERFAMILY SSF102198 11 269 3.01E-58 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_1625 fe209ff58bde689cd7dfdf5ce9794fac 272 Pfam PF04199 Putative cyclase 14 197 8.2E-42 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_1609 484b441ec315483274334185b44c6340 227 SMART SM00849 32 206 3.2E-32 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1609 484b441ec315483274334185b44c6340 227 Gene3D G3DSA:3.60.15.10 7 223 2.2E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1609 484b441ec315483274334185b44c6340 227 SUPERFAMILY SSF56281 19 223 2.36E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1609 484b441ec315483274334185b44c6340 227 Pfam PF00753 Metallo-beta-lactamase superfamily 31 195 6.4E-30 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1765 7748d2923e6c7a78fef4e94d6f719284 285 SUPERFAMILY SSF103481 184 280 9.42E-13 T 23-10-2018 TSIB_1765 7748d2923e6c7a78fef4e94d6f719284 285 SUPERFAMILY SSF103481 35 138 2.88E-12 T 23-10-2018 TSIB_1765 7748d2923e6c7a78fef4e94d6f719284 285 Pfam PF00892 EamA-like transporter family 7 138 9.4E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1765 7748d2923e6c7a78fef4e94d6f719284 285 Pfam PF00892 EamA-like transporter family 151 280 5.1E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1615 d945e56871c6966ba1fe58792506bbe3 144 SUPERFAMILY SSF88697 1 143 2.07E-44 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1615 d945e56871c6966ba1fe58792506bbe3 144 Gene3D G3DSA:3.10.590.10 1 143 2.3E-63 T 23-10-2018 TSIB_1615 d945e56871c6966ba1fe58792506bbe3 144 Pfam PF01878 EVE domain 2 141 6.9E-27 T 23-10-2018 IPR002740 EVE domain TSIB_1615 d945e56871c6966ba1fe58792506bbe3 144 Hamap MF_00771 UPF0310 protein . 1 143 28.323 T 23-10-2018 IPR022996 Uncharacterised protein family UPF0310 TSIB_1830 76bcbffc4f035ac80fe303d9fd6639b5 99 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 6.1E-19 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding TSIB_1736 1e99ce4b0322bdc87698df29fba9a6e9 393 SUPERFAMILY SSF75712 274 336 1.05E-9 T 23-10-2018 TSIB_1736 1e99ce4b0322bdc87698df29fba9a6e9 393 Pfam PF01385 Probable transposase 167 259 3.9E-9 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_1736 1e99ce4b0322bdc87698df29fba9a6e9 393 Pfam PF07282 Putative transposase DNA-binding domain 290 356 2.3E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1736 1e99ce4b0322bdc87698df29fba9a6e9 393 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 4.8E-26 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_1635 9dd38f6bc1024522f71852470ac78585 607 Gene3D G3DSA:3.50.30.10 498 605 4.4E-31 T 23-10-2018 TSIB_1635 9dd38f6bc1024522f71852470ac78585 607 SUPERFAMILY SSF52009 500 602 3.53E-27 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSIB_1635 9dd38f6bc1024522f71852470ac78585 607 Pfam PF00391 PEP-utilising enzyme, mobile domain 527 599 1.8E-22 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSIB_1095 5646b11a6ae234deb7df20f96e8a8a4e 281 Gene3D G3DSA:1.10.10.10 210 281 6.6E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1095 5646b11a6ae234deb7df20f96e8a8a4e 281 Pfam PF12802 MarR family 230 271 1.3E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1095 5646b11a6ae234deb7df20f96e8a8a4e 281 SUPERFAMILY SSF46785 226 280 1.58E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1598 0d4ba8aad35ef2fcdabe132e6c338ba4 148 Gene3D G3DSA:3.30.54.20 70 116 5.7E-56 T 23-10-2018 TSIB_1598 0d4ba8aad35ef2fcdabe132e6c338ba4 148 SUPERFAMILY SSF55186 3 145 1.57E-36 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSIB_1598 0d4ba8aad35ef2fcdabe132e6c338ba4 148 Gene3D G3DSA:3.30.980.10 5 145 5.7E-56 T 23-10-2018 TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 32 459 7.9E-96 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Gene3D G3DSA:3.30.1110.20 45 116 4.2E-22 T 23-10-2018 TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 10 465 59.735 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 SUPERFAMILY SSF53613 3 466 4.36E-153 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Gene3D G3DSA:3.40.1190.20 195 467 2.2E-102 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Gene3D G3DSA:3.40.1190.20 1 44 1.3E-10 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0252 9a0fa15019534ac3daf328e954ca90cf 467 Gene3D G3DSA:3.40.1190.20 117 194 1.1E-23 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0033 4efd6c9f7182e4689f8a85831c972743 247 Pfam PF08608 Wyosine base formation 173 234 8.0E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSIB_0033 4efd6c9f7182e4689f8a85831c972743 247 Gene3D G3DSA:3.20.20.70 1 247 6.2E-80 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0033 4efd6c9f7182e4689f8a85831c972743 247 Pfam PF04055 Radical SAM superfamily 43 171 3.6E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0033 4efd6c9f7182e4689f8a85831c972743 247 SUPERFAMILY SSF102114 56 219 8.04E-17 T 23-10-2018 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 13.863 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 Gene3D G3DSA:3.30.70.330 1 86 3.1E-35 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 SUPERFAMILY SSF54189 4 78 1.83E-25 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 Pfam PF00276 Ribosomal protein L23 5 72 1.2E-17 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 2.4E-36 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0290 d6a8449f9d2589880aa44bc4a3bdc978 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 26.029 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 Gene3D G3DSA:3.40.50.720 1 128 1.7E-47 T 23-10-2018 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 SUPERFAMILY SSF52210 130 292 8.9E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 SUPERFAMILY SSF51735 2 136 9.22E-41 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 Pfam PF13380 CoA binding domain 11 133 5.8E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 SMART SM00881 6 101 1.4E-40 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 Gene3D G3DSA:3.40.50.261 129 294 3.3E-62 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 291 2.0E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 Gene3D G3DSA:3.40.50.261 295 459 2.0E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_1965 90ba718c8c0429cb03a61cf3fc1d5a23 462 SUPERFAMILY SSF52210 299 456 2.49E-34 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_2000 fbee0782dd1ad96b5a016f1c2831f2a8 157 SUPERFAMILY SSF48452 53 139 7.4E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_2000 fbee0782dd1ad96b5a016f1c2831f2a8 157 Gene3D G3DSA:1.25.40.10 47 156 2.7E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_2000 fbee0782dd1ad96b5a016f1c2831f2a8 157 Gene3D G3DSA:1.25.40.10 2 46 1.4E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0404 d152aeb2725745906470031bc93740c6 107 SUPERFAMILY SSF46785 3 106 2.29E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0404 d152aeb2725745906470031bc93740c6 107 Gene3D G3DSA:1.10.10.10 2 107 2.6E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0404 d152aeb2725745906470031bc93740c6 107 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 5.4E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSIB_1515 81b37de79d0e447a43e6009048e0f24d 305 Pfam PF00152 tRNA synthetases class II (D, K and N) 8 298 1.4E-43 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1515 81b37de79d0e447a43e6009048e0f24d 305 SUPERFAMILY SSF55681 9 301 4.15E-55 T 23-10-2018 TSIB_1515 81b37de79d0e447a43e6009048e0f24d 305 Gene3D G3DSA:3.30.930.10 5 304 5.9E-76 T 23-10-2018 TSIB_1681 52f9bbc5bd203716881d24eca767c41e 384 Pfam PF00535 Glycosyl transferase family 2 9 138 2.6E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_1681 52f9bbc5bd203716881d24eca767c41e 384 SUPERFAMILY SSF53448 7 377 1.78E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1681 52f9bbc5bd203716881d24eca767c41e 384 Gene3D G3DSA:3.90.550.10 3 271 2.0E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1982 9c05ca6403fda03c508b23632dc63130 249 Pfam PF01061 ABC-2 type transporter 15 216 9.5E-18 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSIB_1982 9c05ca6403fda03c508b23632dc63130 249 PIRSF PIRSF006648 4 247 2.2E-23 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_0251 5fbc8df5a8269852d8d0e3b2d79f72b8 394 Gene3D G3DSA:3.90.550.10 1 394 1.3E-162 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0251 5fbc8df5a8269852d8d0e3b2d79f72b8 394 SUPERFAMILY SSF53448 56 183 7.65E-5 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0251 5fbc8df5a8269852d8d0e3b2d79f72b8 394 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 382 7.1E-191 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 TSIB_0251 5fbc8df5a8269852d8d0e3b2d79f72b8 394 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 381 2.9E-159 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 TSIB_1282 5783326297bcd3b667ceb7087d84f855 152 Gene3D G3DSA:3.30.70.3270 28 151 3.3E-14 T 23-10-2018 TSIB_1282 5783326297bcd3b667ceb7087d84f855 152 Pfam PF13237 4Fe-4S dicluster domain 58 108 4.1E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1282 5783326297bcd3b667ceb7087d84f855 152 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1282 5783326297bcd3b667ceb7087d84f855 152 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1282 5783326297bcd3b667ceb7087d84f855 152 SUPERFAMILY SSF54862 53 110 1.07E-18 T 23-10-2018 TSIB_1003 08ab39e9fba73132eb57fca76fec6d62 241 SUPERFAMILY SSF52540 18 226 1.55E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1003 08ab39e9fba73132eb57fca76fec6d62 241 Hamap MF_02040 Iron-sulfur cluster carrier protein. 11 238 27.274 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TSIB_1003 08ab39e9fba73132eb57fca76fec6d62 241 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 15 237 5.1E-55 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TSIB_1003 08ab39e9fba73132eb57fca76fec6d62 241 Gene3D G3DSA:3.40.50.300 1 223 3.6E-65 T 23-10-2018 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 SUPERFAMILY SSF54368 16 90 1.24E-17 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 Gene3D G3DSA:3.10.20.70 5 99 3.4E-21 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 14 438 9.7E-163 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 91 3.9E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 223 238 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 Gene3D G3DSA:3.30.590.10 100 439 7.5E-121 T 23-10-2018 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 SMART SM01230 97 340 9.4E-128 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 Pfam PF00120 Glutamine synthetase, catalytic domain 98 418 7.0E-124 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSIB_1761 0b8cebefbddab93f697bed396374eac2 440 SUPERFAMILY SSF55931 99 438 1.57E-116 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSIB_1558 1d010eba74660d5636e37f88f3bb0588 282 SUPERFAMILY SSF103481 41 142 2.75E-13 T 23-10-2018 TSIB_1558 1d010eba74660d5636e37f88f3bb0588 282 Pfam PF00892 EamA-like transporter family 7 140 3.6E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1558 1d010eba74660d5636e37f88f3bb0588 282 Pfam PF00892 EamA-like transporter family 149 272 1.1E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_1558 1d010eba74660d5636e37f88f3bb0588 282 SUPERFAMILY SSF103481 182 274 1.96E-7 T 23-10-2018 TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 Gene3D G3DSA:1.10.8.60 157 220 1.1E-10 T 23-10-2018 TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 43 152 1.7E-13 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 SUPERFAMILY SSF52540 2 209 1.02E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 Hamap MF_01508 Replication factor C large subunit [rfcL]. 2 445 33.832 T 23-10-2018 IPR023935 Replication factor C, large subunit TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 Gene3D G3DSA:3.40.50.300 3 154 1.2E-34 T 23-10-2018 TSIB_0102 6b067a94cdf2394eee6c7b59a1e7b0b2 487 SMART SM00382 39 156 1.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 16 194 1.2E-58 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 Pfam PF01871 AMMECR1 18 194 2.5E-52 T 23-10-2018 IPR002733 AMMECR1 domain TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 Gene3D G3DSA:3.30.700.20 10 201 8.5E-74 T 23-10-2018 IPR027485 AMMECR1, N-terminal TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 Hamap MF_00645 Protein . 9 192 40.267 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 Gene3D G3DSA:3.30.1490.150 117 190 8.5E-74 T 23-10-2018 TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 7 201 7.8E-68 T 23-10-2018 IPR023473 AMMECR1 TSIB_0916 0d4e00091e4173d0d3b9643ca583bc93 207 SUPERFAMILY SSF143447 4 204 2.62E-68 T 23-10-2018 IPR036071 AMMECR1 domain superfamily TSIB_1390 b2fc953bb43a6aaa16e39bb236d4ad47 131 Pfam PF09946 Predicted membrane protein (DUF2178) 16 119 3.1E-18 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane TSIB_0376 18d027412093032b76dc601069368c58 328 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 9 319 5.8E-101 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSIB_0376 18d027412093032b76dc601069368c58 328 Gene3D G3DSA:3.40.190.10 119 256 9.5E-102 T 23-10-2018 TSIB_0376 18d027412093032b76dc601069368c58 328 Gene3D G3DSA:3.40.190.10 37 319 9.5E-102 T 23-10-2018 TSIB_0376 18d027412093032b76dc601069368c58 328 SUPERFAMILY SSF53850 33 320 3.07E-77 T 23-10-2018 TSIB_0376 18d027412093032b76dc601069368c58 328 Pfam PF16868 NMT1-like family 37 319 3.0E-86 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSIB_1264 585f7b22ebea1916bdc65c6fe4714ba8 100 PIRSF PIRSF029904 1 99 2.0E-31 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TSIB_1264 585f7b22ebea1916bdc65c6fe4714ba8 100 SUPERFAMILY SSF101386 2 92 1.64E-20 T 23-10-2018 TSIB_1264 585f7b22ebea1916bdc65c6fe4714ba8 100 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 94 2.7E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSIB_1264 585f7b22ebea1916bdc65c6fe4714ba8 100 Gene3D G3DSA:1.10.287.1080 1 98 1.7E-26 T 23-10-2018 TSIB_1780 f558306c9432359699618b836206a45a 457 SUPERFAMILY SSF53756 2 447 3.25E-81 T 23-10-2018 TSIB_1780 f558306c9432359699618b836206a45a 457 Gene3D G3DSA:3.40.50.2000 222 435 2.4E-112 T 23-10-2018 TSIB_1780 f558306c9432359699618b836206a45a 457 Pfam PF00534 Glycosyl transferases group 1 254 427 1.3E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_1780 f558306c9432359699618b836206a45a 457 Gene3D G3DSA:3.40.50.2000 3 445 2.4E-112 T 23-10-2018 TSIB_1780 f558306c9432359699618b836206a45a 457 Pfam PF08323 Starch synthase catalytic domain 3 208 2.6E-34 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 SUPERFAMILY SSF50249 3 101 5.36E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 Gene3D G3DSA:3.30.930.10 106 431 4.9E-115 T 23-10-2018 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 112 425 1.1E-84 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 Gene3D G3DSA:2.40.50.140 2 103 2.7E-28 T 23-10-2018 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 SUPERFAMILY SSF55681 112 426 1.36E-87 T 23-10-2018 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 430 4.3E-127 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TSIB_0994 f83cc62a99933cf6815b72e709608a45 431 Pfam PF01336 OB-fold nucleic acid binding domain 20 98 3.2E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 PIRSF PIRSF002122 1 217 2.7E-49 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 17 217 39.031 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 17 217 6.2E-90 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 Gene3D G3DSA:1.10.455.10 17 217 4.9E-81 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 Pfam PF00177 Ribosomal protein S7p/S5e 60 217 1.7E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain TSIB_0394 92a64900c2ea59dca36eef6de22a23f5 217 SUPERFAMILY SSF47973 18 217 1.44E-62 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSIB_0480 0b3f0b84b0d17d1aabb8e08522555ffb 216 SUPERFAMILY SSF53448 5 203 2.81E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0480 0b3f0b84b0d17d1aabb8e08522555ffb 216 Pfam PF00535 Glycosyl transferase family 2 8 162 4.0E-40 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_0480 0b3f0b84b0d17d1aabb8e08522555ffb 216 Gene3D G3DSA:3.90.550.10 2 212 4.1E-65 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 SUPERFAMILY SSF51735 5 132 2.19E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 SUPERFAMILY SSF52210 294 450 2.09E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 Gene3D G3DSA:3.40.50.261 132 291 2.9E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 SMART SM00881 9 102 6.9E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 6 447 2.7E-172 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 289 8.0E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 Gene3D G3DSA:3.40.50.720 5 131 2.2E-46 T 23-10-2018 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 Gene3D G3DSA:3.40.50.261 292 456 8.0E-66 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 Pfam PF13380 CoA binding domain 13 136 3.1E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0147 1d2467954ace47c9d2bee36dd404fecc 457 SUPERFAMILY SSF52210 134 290 1.26E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSIB_0361 12dcd41dcdf17ffa25694e7208c4067f 418 Gene3D G3DSA:3.40.50.2000 207 403 1.3E-162 T 23-10-2018 TSIB_0361 12dcd41dcdf17ffa25694e7208c4067f 418 SUPERFAMILY SSF53756 48 417 5.89E-56 T 23-10-2018 TSIB_0361 12dcd41dcdf17ffa25694e7208c4067f 418 Pfam PF00534 Glycosyl transferases group 1 227 397 1.3E-27 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_0361 12dcd41dcdf17ffa25694e7208c4067f 418 Gene3D G3DSA:3.40.50.2000 21 206 1.3E-162 T 23-10-2018 TSIB_1178 f7a26163443bfc566a12e95b64705511 252 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 160 8.2E-12 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSIB_1178 f7a26163443bfc566a12e95b64705511 252 Gene3D G3DSA:3.30.930.10 10 252 7.0E-64 T 23-10-2018 TSIB_1178 f7a26163443bfc566a12e95b64705511 252 SUPERFAMILY SSF55681 3 252 2.06E-68 T 23-10-2018 TSIB_1724 432f37b7415151ec50977e54b4e32e7f 326 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 263 323 3.2E-6 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_1724 432f37b7415151ec50977e54b4e32e7f 326 Pfam PF00899 ThiF family 12 230 1.7E-44 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TSIB_1724 432f37b7415151ec50977e54b4e32e7f 326 Gene3D G3DSA:3.40.50.720 8 239 1.7E-58 T 23-10-2018 TSIB_1724 432f37b7415151ec50977e54b4e32e7f 326 SUPERFAMILY SSF69572 11 260 5.62E-65 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TSIB_1724 432f37b7415151ec50977e54b4e32e7f 326 Gene3D G3DSA:3.30.310.10 262 325 1.4E-5 T 23-10-2018 IPR012295 TBP domain superfamily TSIB_0278 76379f31f06694bf67195baacaa2b82c 320 Gene3D G3DSA:3.20.20.70 28 240 2.6E-23 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0278 76379f31f06694bf67195baacaa2b82c 320 Pfam PF04055 Radical SAM superfamily 42 200 9.2E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0278 76379f31f06694bf67195baacaa2b82c 320 SMART SM00729 33 237 9.8E-18 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0278 76379f31f06694bf67195baacaa2b82c 320 SUPERFAMILY SSF102114 27 294 2.09E-31 T 23-10-2018 TSIB_1501 290e39aa43b112a37907ac021d0358cc 215 Gene3D G3DSA:3.40.50.11570 4 214 8.3E-64 T 23-10-2018 TSIB_1501 290e39aa43b112a37907ac021d0358cc 215 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 212 1.4E-61 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_1671 cfa91ae53813a1fe39a1ff879689af8d 135 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 14 64 2.4E-4 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 TSIB_2035 b09f22f9fda18f329e23466080df498e 431 Gene3D G3DSA:3.40.50.300 69 155 4.3E-8 T 23-10-2018 TSIB_2035 b09f22f9fda18f329e23466080df498e 431 Pfam PF13173 AAA domain 35 167 4.6E-38 T 23-10-2018 TSIB_2035 b09f22f9fda18f329e23466080df498e 431 SUPERFAMILY SSF52540 29 232 2.6E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_2035 b09f22f9fda18f329e23466080df498e 431 Pfam PF13635 Domain of unknown function (DUF4143) 230 364 5.2E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 Gene3D G3DSA:3.30.870.10 110 248 2.3E-67 T 23-10-2018 TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 SUPERFAMILY SSF46785 3 87 4.39E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 Gene3D G3DSA:1.10.10.10 1 104 1.4E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 Pfam PF11495 Archaeal transcriptional regulator TrmB 110 335 6.0E-48 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 Gene3D G3DSA:2.30.30.690 249 338 3.6E-41 T 23-10-2018 TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 SUPERFAMILY SSF56024 110 245 2.59E-72 T 23-10-2018 TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 77 2.2E-21 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_0362 2be0a14207f4189301c4dce9df98aa05 338 SUPERFAMILY SSF159071 248 336 4.45E-24 T 23-10-2018 TSIB_0942 bc97edf9a810aa909ec8c708e9352b0a 579 Pfam PF03169 OPT oligopeptide transporter protein 18 571 2.7E-63 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TSIB_0942 bc97edf9a810aa909ec8c708e9352b0a 579 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 7.2E-6 T 23-10-2018 TSIB_0942 bc97edf9a810aa909ec8c708e9352b0a 579 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 7.2E-6 T 23-10-2018 TSIB_0942 bc97edf9a810aa909ec8c708e9352b0a 579 PRINTS PR00173 Glutamate-aspartate symporter signature 267 286 7.2E-6 T 23-10-2018 TSIB_0942 bc97edf9a810aa909ec8c708e9352b0a 579 PRINTS PR00173 Glutamate-aspartate symporter signature 397 416 7.2E-6 T 23-10-2018 TSIB_0202 206e19b8e553a0edbf08bf3fa96faf29 220 Pfam PF01863 Protein of unknown function DUF45 21 201 1.7E-45 T 23-10-2018 IPR002725 Protein of unknown function DUF45 TSIB_0202 206e19b8e553a0edbf08bf3fa96faf29 220 Gene3D G3DSA:3.30.2010.10 110 207 9.1E-19 T 23-10-2018 TSIB_0122 dfbb0cedfb8859a6885a14ab4ced6a1e 453 PIRSF PIRSF005353 3 450 2.1E-169 T 23-10-2018 IPR026033 Purine permease PbuG-like TSIB_0122 dfbb0cedfb8859a6885a14ab4ced6a1e 453 Pfam PF00860 Permease family 28 408 6.3E-46 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TSIB_1894 7865a0d3cac8f6b1577d684f8ab34143 124 SUPERFAMILY SSF49367 2 123 8.11E-43 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TSIB_1894 7865a0d3cac8f6b1577d684f8ab34143 124 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 123 4.3E-36 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TSIB_1894 7865a0d3cac8f6b1577d684f8ab34143 124 Pfam PF01880 Desulfoferrodoxin 9 120 2.1E-31 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TSIB_1894 7865a0d3cac8f6b1577d684f8ab34143 124 Gene3D G3DSA:2.60.40.730 1 124 2.7E-52 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TSIB_0908 d8ef5fa23263e89e107d7cd9c317f299 91 Gene3D G3DSA:1.20.1440.50 8 91 8.4E-30 T 23-10-2018 IPR023130 Ta0600-like superfamily TSIB_0908 d8ef5fa23263e89e107d7cd9c317f299 91 Pfam PF03685 Uncharacterised protein family (UPF0147) 12 90 6.3E-32 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TSIB_0908 d8ef5fa23263e89e107d7cd9c317f299 91 Hamap MF_00342 UPF0147 protein . 9 91 28.358 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TSIB_0908 d8ef5fa23263e89e107d7cd9c317f299 91 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 13 91 1.0E-28 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TSIB_0908 d8ef5fa23263e89e107d7cd9c317f299 91 SUPERFAMILY SSF158436 5 91 2.62E-29 T 23-10-2018 TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 PIRSF PIRSF006443 7 176 1.9E-57 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 Pfam PF00994 Probable molybdopterin binding domain 24 166 3.5E-38 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 Gene3D G3DSA:3.40.980.10 19 176 6.2E-50 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 21 165 2.7E-39 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 82 95 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 SUPERFAMILY SSF53218 20 174 5.63E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSIB_0964 ea5822fcc85d03be8ad3ded38dd34004 176 SMART SM00852 24 170 9.7E-31 T 23-10-2018 IPR001453 MoaB/Mog domain TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 SUPERFAMILY SSF53795 244 605 1.97E-103 T 23-10-2018 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 605 1.6E-104 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 606 35.296 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Gene3D G3DSA:3.40.449.10 27 246 2.3E-145 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 29 239 4.7E-58 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Gene3D G3DSA:2.170.8.10 65 398 2.3E-145 T 23-10-2018 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 PIRSF PIRSF001348 5 609 1.6E-204 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 Gene3D G3DSA:3.90.228.20 247 603 2.3E-145 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSIB_0151 1ee01b37f38ef0002a518fd1427494e3 622 SUPERFAMILY SSF68923 12 243 4.29E-60 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSIB_0624 f6db2d15d7f835e75bf0232ce3379c1f 131 Pfam PF12646 Domain of unknown function (DUF3783) 56 111 3.3E-17 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TSIB_0624 f6db2d15d7f835e75bf0232ce3379c1f 131 PIRSF PIRSF014543 1 122 7.9E-42 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TSIB_1726 c1ab2ddf9de44e700186b9f3b05e48bb 149 Gene3D G3DSA:3.40.50.360 1 148 2.5E-32 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1726 c1ab2ddf9de44e700186b9f3b05e48bb 149 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 23-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TSIB_1726 c1ab2ddf9de44e700186b9f3b05e48bb 149 SUPERFAMILY SSF52218 1 126 4.19E-19 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1726 c1ab2ddf9de44e700186b9f3b05e48bb 149 Pfam PF12682 Flavodoxin 2 115 7.8E-6 T 23-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TSIB_1057 60a18c27c7f77051804ecc4c09ab0149 157 Pfam PF01927 Mut7-C RNAse domain 7 146 2.4E-44 T 23-10-2018 IPR002782 Mut7-C RNAse domain TSIB_1175 aca47d52cf7a9ae30a0d95ce5db32878 248 Gene3D G3DSA:3.40.50.300 7 248 7.3E-74 T 23-10-2018 TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 12 129 2.0E-27 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 Gene3D G3DSA:3.40.1350.10 2 134 4.5E-38 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 10 95 3.2E-29 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 PIRSF PIRSF004985 2 131 3.3E-40 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 SUPERFAMILY SSF52980 5 112 4.69E-28 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSIB_1511 d0dbed20524322139d6c7ddf2754136b 136 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 4 129 38.439 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TSIB_0459 3266cb6adb377531ebd0f94fa9b9c1e7 392 Pfam PF00999 Sodium/hydrogen exchanger family 9 379 1.4E-53 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSIB_0459 3266cb6adb377531ebd0f94fa9b9c1e7 392 Gene3D G3DSA:1.20.1530.20 1 392 2.6E-75 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_0664 079f8cae9bf1a0800962aa930dbc8259 245 Pfam PF04016 Putative heavy-metal chelation 105 232 1.4E-36 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain TSIB_0664 079f8cae9bf1a0800962aa930dbc8259 245 SUPERFAMILY SSF159713 6 243 4.05E-60 T 23-10-2018 TSIB_0664 079f8cae9bf1a0800962aa930dbc8259 245 Gene3D G3DSA:3.40.50.11590 105 216 1.6E-27 T 23-10-2018 TSIB_0664 079f8cae9bf1a0800962aa930dbc8259 245 Pfam PF13938 Putative heavy-metal chelation 8 90 1.5E-15 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 TSIB_0664 079f8cae9bf1a0800962aa930dbc8259 245 Gene3D G3DSA:3.30.390.100 11 219 1.6E-27 T 23-10-2018 TSIB_0317 0c17b29a5da89eab185069de8cd38880 83 Pfam PF01929 Ribosomal protein L14 44 81 1.1E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0317 0c17b29a5da89eab185069de8cd38880 83 Gene3D G3DSA:2.30.30.30 2 83 6.8E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSIB_0317 0c17b29a5da89eab185069de8cd38880 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.972 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 TSIB_0317 0c17b29a5da89eab185069de8cd38880 83 SUPERFAMILY SSF50104 2 80 7.62E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSIB_1661 4f0dc65d718c9931249ab2c0ecb99da8 179 SMART SM00471 26 142 3.5E-11 T 23-10-2018 IPR003607 HD/PDEase domain TSIB_1661 4f0dc65d718c9931249ab2c0ecb99da8 179 Gene3D G3DSA:1.10.3210.10 1 179 3.4E-58 T 23-10-2018 TSIB_1661 4f0dc65d718c9931249ab2c0ecb99da8 179 SUPERFAMILY SSF109604 2 173 5.97E-37 T 23-10-2018 TSIB_1661 4f0dc65d718c9931249ab2c0ecb99da8 179 Pfam PF13023 HD domain 9 155 3.6E-26 T 23-10-2018 IPR006674 HD domain TSIB_1020 c5f185441e05cd0a3c6315727df808f9 246 SUPERFAMILY SSF75217 2 167 3.6E-37 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TSIB_1020 c5f185441e05cd0a3c6315727df808f9 246 Gene3D G3DSA:3.40.1280.10 1 164 3.2E-52 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSIB_1020 c5f185441e05cd0a3c6315727df808f9 246 PIRSF PIRSF004808 1 243 2.6E-73 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSIB_1020 c5f185441e05cd0a3c6315727df808f9 246 Pfam PF00588 SpoU rRNA Methylase family 3 154 2.1E-36 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSIB_1020 c5f185441e05cd0a3c6315727df808f9 246 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 2 233 1.9E-66 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 Gene3D G3DSA:1.10.287.1080 1 105 5.0E-34 T 23-10-2018 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 Gene3D G3DSA:3.90.960.10 106 250 5.3E-33 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 SUPERFAMILY SSF101386 2 105 3.49E-28 T 23-10-2018 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 SUPERFAMILY SSF55826 123 248 1.09E-28 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 Pfam PF12643 MazG-like family 30 105 1.6E-19 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TSIB_1782 c462f161632eb0cddcaed7dc32b171ce 250 Pfam PF04073 Aminoacyl-tRNA editing domain 125 240 1.6E-24 T 23-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TSIB_0246 c92f749d5f12d717bc2d9b146bd0ce49 288 Gene3D G3DSA:3.40.800.10 19 288 4.7E-75 T 23-10-2018 TSIB_0246 c92f749d5f12d717bc2d9b146bd0ce49 288 Pfam PF00491 Arginase family 26 283 9.9E-62 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_0246 c92f749d5f12d717bc2d9b146bd0ce49 288 SUPERFAMILY SSF52768 19 286 5.94E-73 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TSIB_0246 c92f749d5f12d717bc2d9b146bd0ce49 288 TIGRFAM TIGR01230 agmatinase: agmatinase 21 284 4.7E-74 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TSIB_0246 c92f749d5f12d717bc2d9b146bd0ce49 288 PIRSF PIRSF036979 2 288 1.9E-84 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_1712 3624255f7bc6c95a47f9e81750f999bd 74 Pfam PF00403 Heavy-metal-associated domain 7 66 7.7E-11 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSIB_1712 3624255f7bc6c95a47f9e81750f999bd 74 SUPERFAMILY SSF55008 3 69 1.57E-17 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSIB_1712 3624255f7bc6c95a47f9e81750f999bd 74 Gene3D G3DSA:3.30.70.100 3 70 1.9E-16 T 23-10-2018 TSIB_0338 5bdfbf104c1ecf1d0d6a97111f84cacc 195 Gene3D G3DSA:3.40.50.150 5 193 1.3E-45 T 23-10-2018 TSIB_0338 5bdfbf104c1ecf1d0d6a97111f84cacc 195 Pfam PF05175 Methyltransferase small domain 27 191 3.1E-42 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSIB_0338 5bdfbf104c1ecf1d0d6a97111f84cacc 195 SUPERFAMILY SSF53335 6 191 1.72E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 Pfam PF01194 RNA polymerases N / 8 kDa subunit 4 62 1.8E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 5 14 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 PIRSF PIRSF005653 4 68 7.3E-33 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 SUPERFAMILY SSF46924 4 66 2.75E-28 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 Gene3D G3DSA:1.10.10.60 4 68 1.2E-33 T 23-10-2018 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 4 66 23.935 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_0346 6aa6b4b1e64c5e32b00f19d8e5380281 68 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 13 52 5.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 276 1.7E-50 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 Gene3D G3DSA:3.50.50.60 2 370 3.3E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 SUPERFAMILY SSF51905 7 287 6.49E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 Pfam PF01494 FAD binding domain 80 186 1.0E-7 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 47 4.2E-5 T 23-10-2018 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 249 264 1.1E-11 T 23-10-2018 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-11 T 23-10-2018 TSIB_1013 646bd3e9235011dfef8f7b3ad282143f 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 138 153 1.1E-11 T 23-10-2018 TSIB_1955 9cee32df8d1b42388468727d7127f315 308 Gene3D G3DSA:1.20.81.30 91 208 7.8E-7 T 23-10-2018 TSIB_1955 9cee32df8d1b42388468727d7127f315 308 Pfam PF00482 Type II secretion system (T2SS), protein F 104 227 4.0E-16 T 23-10-2018 IPR018076 Type II secretion system F domain TSIB_0365 3b40a758f451bd59bd7fd02b5e1128bf 637 SUPERFAMILY SSF48208 233 630 3.78E-69 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSIB_0365 3b40a758f451bd59bd7fd02b5e1128bf 637 Gene3D G3DSA:1.50.10.10 219 589 7.8E-43 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSIB_0365 3b40a758f451bd59bd7fd02b5e1128bf 637 Pfam PF06202 Amylo-alpha-1,6-glucosidase 232 581 8.9E-15 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 TSIB_0365 3b40a758f451bd59bd7fd02b5e1128bf 637 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 7 173 8.0E-15 T 23-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal TSIB_0149 14d4ec61bef25dd4e33383503ae7b428 238 Gene3D G3DSA:3.40.120.10 3 118 2.0E-6 T 23-10-2018 TSIB_0149 14d4ec61bef25dd4e33383503ae7b428 238 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 71 2.2E-6 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0149 14d4ec61bef25dd4e33383503ae7b428 238 SUPERFAMILY SSF53738 10 77 2.12E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0149 14d4ec61bef25dd4e33383503ae7b428 238 SUPERFAMILY SSF53738 130 211 1.65E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0358 c13a2181a6af074edb2a4b8fbb3a7680 435 Pfam PF01547 Bacterial extracellular solute-binding protein 72 354 6.4E-43 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSIB_0358 c13a2181a6af074edb2a4b8fbb3a7680 435 Gene3D G3DSA:3.40.190.10 56 432 1.6E-63 T 23-10-2018 TSIB_0358 c13a2181a6af074edb2a4b8fbb3a7680 435 SUPERFAMILY SSF53850 45 432 1.29E-67 T 23-10-2018 TSIB_1403 1ebaece72261122c96128bf94ce82d3e 215 Pfam PF02811 PHP domain 2 157 9.7E-11 T 23-10-2018 IPR004013 PHP domain GO:0003824 TSIB_1403 1ebaece72261122c96128bf94ce82d3e 215 SUPERFAMILY SSF89550 2 211 4.58E-42 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSIB_1403 1ebaece72261122c96128bf94ce82d3e 215 Gene3D G3DSA:3.20.20.140 1 214 3.6E-53 T 23-10-2018 TSIB_1403 1ebaece72261122c96128bf94ce82d3e 215 SMART SM00481 1 73 1.7E-16 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TSIB_2061 f7c015194818aebe09fcafa260103be1 402 Pfam PF00534 Glycosyl transferases group 1 219 383 7.9E-39 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_2061 f7c015194818aebe09fcafa260103be1 402 Pfam PF13439 Glycosyltransferase Family 4 98 206 1.6E-17 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSIB_2061 f7c015194818aebe09fcafa260103be1 402 SUPERFAMILY SSF53756 89 397 1.77E-84 T 23-10-2018 TSIB_2061 f7c015194818aebe09fcafa260103be1 402 Gene3D G3DSA:3.40.50.2000 102 397 1.7E-76 T 23-10-2018 TSIB_2061 f7c015194818aebe09fcafa260103be1 402 Gene3D G3DSA:3.40.50.2000 205 384 1.7E-76 T 23-10-2018 TSIB_0928 9b59e6e6e2460d09881a11faeb41b4bb 205 Gene3D G3DSA:3.40.50.11570 4 205 2.4E-12 T 23-10-2018 TSIB_0928 9b59e6e6e2460d09881a11faeb41b4bb 205 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 204 8.1E-12 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_1890 6b7f8c63fb87eaebd5c612ffb4bee99b 300 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 293 1.4E-68 T 23-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TSIB_1890 6b7f8c63fb87eaebd5c612ffb4bee99b 300 Gene3D G3DSA:3.40.190.120 133 236 6.0E-101 T 23-10-2018 TSIB_1890 6b7f8c63fb87eaebd5c612ffb4bee99b 300 SUPERFAMILY SSF53850 30 297 8.45E-73 T 23-10-2018 TSIB_1890 6b7f8c63fb87eaebd5c612ffb4bee99b 300 Gene3D G3DSA:3.40.190.10 32 297 6.0E-101 T 23-10-2018 TSIB_1557 5d9d534ccb06857d893890a08f47093a 354 SUPERFAMILY SSF53383 24 350 3.48E-65 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1557 5d9d534ccb06857d893890a08f47093a 354 Pfam PF00155 Aminotransferase class I and II 34 352 3.7E-46 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1557 5d9d534ccb06857d893890a08f47093a 354 Gene3D G3DSA:3.40.640.10 42 267 7.8E-75 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1557 5d9d534ccb06857d893890a08f47093a 354 Gene3D G3DSA:3.90.1150.10 32 348 7.8E-75 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0730 35e795fc083486c99f7b3ba923f71607 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.26 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSIB_0730 35e795fc083486c99f7b3ba923f71607 255 Pfam PF03746 LamB/YcsF family 3 241 2.0E-104 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSIB_0730 35e795fc083486c99f7b3ba923f71607 255 Gene3D G3DSA:3.20.20.370 1 255 4.0E-110 T 23-10-2018 TSIB_0730 35e795fc083486c99f7b3ba923f71607 255 SUPERFAMILY SSF88713 1 252 1.06E-103 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSIB_0660 fc4d575efb2a50510e5c4f8ca30d66a3 200 Gene3D G3DSA:3.50.30.50 9 199 1.1E-59 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_0660 fc4d575efb2a50510e5c4f8ca30d66a3 200 SUPERFAMILY SSF102198 12 197 6.28E-58 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_0660 fc4d575efb2a50510e5c4f8ca30d66a3 200 Pfam PF04199 Putative cyclase 13 143 8.4E-25 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSIB_0028 906fb82f4fee66198ae7369b32844edc 180 Pfam PF04019 Protein of unknown function (DUF359) 53 174 8.5E-40 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TSIB_0028 906fb82f4fee66198ae7369b32844edc 180 Hamap MF_00590 UPF0218 protein . 9 176 29.907 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TSIB_0028 906fb82f4fee66198ae7369b32844edc 180 PIRSF PIRSF006533 4 178 7.2E-57 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 20 36 1.2E-12 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 5 12 1.2E-12 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 41 57 1.2E-12 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 Gene3D G3DSA:2.40.50.970 4 77 5.1E-33 T 23-10-2018 IPR037254 HupF/HypC superfamily TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 SUPERFAMILY SSF159127 4 77 1.83E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 Pfam PF01455 HupF/HypC family 4 68 3.4E-29 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSIB_1435 1afbc0f4b739978caacea645eb00cb9d 77 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 4 77 5.5E-29 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSIB_1698 99b4db18c1530dab8d221a11daed42ce 146 SUPERFAMILY SSF82784 3 127 2.49E-29 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TSIB_1698 99b4db18c1530dab8d221a11daed42ce 146 Pfam PF02566 OsmC-like protein 37 131 1.7E-19 T 23-10-2018 IPR003718 OsmC/Ohr family TSIB_1698 99b4db18c1530dab8d221a11daed42ce 146 Gene3D G3DSA:3.30.300.20 2 124 1.1E-25 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 SUPERFAMILY SSF54211 9 212 2.33E-57 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 Gene3D G3DSA:3.30.230.70 1 268 9.1E-89 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 44.718 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 SUPERFAMILY SSF55666 184 268 5.47E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 Pfam PF01138 3' exoribonuclease family, domain 1 29 164 5.0E-31 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1348 f6b2eb7028801d0c36d10cbfe9aab3c6 269 Pfam PF03725 3' exoribonuclease family, domain 2 189 253 8.1E-15 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_0909 c7f054f32786fe29af5c74d4108cc0b0 179 Gene3D G3DSA:3.40.50.300 2 179 3.8E-65 T 23-10-2018 TSIB_0909 c7f054f32786fe29af5c74d4108cc0b0 179 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 7 179 3.8E-68 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSIB_0909 c7f054f32786fe29af5c74d4108cc0b0 179 PIRSF PIRSF015617 2 179 9.0E-63 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSIB_0909 c7f054f32786fe29af5c74d4108cc0b0 179 SUPERFAMILY SSF52540 7 179 1.13E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0909 c7f054f32786fe29af5c74d4108cc0b0 179 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 12 179 4.5E-61 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSIB_0140 4494a65bacca3dfe5337af51a3da74e5 513 Gene3D G3DSA:3.60.15.10 449 513 1.2E-5 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0140 4494a65bacca3dfe5337af51a3da74e5 513 SUPERFAMILY SSF56281 1 512 2.71E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0140 4494a65bacca3dfe5337af51a3da74e5 513 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 461 490 1.2E-4 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSIB_1225 ffad5ca978db6d6831cfa2fb88fb6344 140 Gene3D G3DSA:1.20.120.580 4 140 1.7E-17 T 23-10-2018 IPR037038 Bsu32300-like superfamily TSIB_1225 ffad5ca978db6d6831cfa2fb88fb6344 140 Pfam PF01934 Protein of unknown function DUF86 13 132 8.8E-23 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TSIB_1911 4c19733c5f85b6823cf58c13a42f79d6 494 Pfam PF00361 Proton-conducting membrane transporter 129 417 1.5E-62 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1911 4c19733c5f85b6823cf58c13a42f79d6 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 7.8E-5 T 23-10-2018 TSIB_1911 4c19733c5f85b6823cf58c13a42f79d6 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 7.8E-5 T 23-10-2018 TSIB_1911 4c19733c5f85b6823cf58c13a42f79d6 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 215 236 7.8E-5 T 23-10-2018 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 SUPERFAMILY SSF56228 1 209 2.35E-84 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 206 7.9E-89 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 Gene3D G3DSA:1.10.599.10 240 601 1.9E-158 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 Gene3D G3DSA:1.10.569.10 242 427 1.9E-158 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 SMART SM00790 4 207 2.6E-137 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 Gene3D G3DSA:3.60.9.10 1 211 1.5E-98 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 SUPERFAMILY SSF48310 212 603 6.41E-154 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1009 6de2f4fd32a103eeaba27330047b5cdf 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 601 1.1E-149 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1939 49951b1902555973a377d5a6010f6f5e 129 Pfam PF04021 Class III signal peptide 6 29 1.2E-5 T 23-10-2018 IPR007166 Class III signal peptide motif TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 173 3.8E-46 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 SUPERFAMILY SSF55154 2 173 4.91E-36 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 Pfam PF01928 CYTH domain 1 164 5.7E-31 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 SMART SM01118 1 175 8.8E-22 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 3.0E-60 T 23-10-2018 TSIB_1506 fb70f27af6c713e28275ec9c6606837c 183 Gene3D G3DSA:2.40.320.10 1 180 7.0E-55 T 23-10-2018 TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 SUPERFAMILY SSF52540 3 225 4.02E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 SMART SM00382 28 211 7.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 Gene3D G3DSA:3.40.50.300 1 238 4.9E-66 T 23-10-2018 TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 Pfam PF00005 ABC transporter 19 163 1.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1549 9a7d639d35eab4d22cb63264ec4360b3 308 Pfam PF13732 Domain of unknown function (DUF4162) 216 301 8.7E-11 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 Pfam PF00301 Rubredoxin 3 49 1.6E-25 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 Gene3D G3DSA:2.20.28.10 2 54 4.2E-30 T 23-10-2018 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 PIRSF PIRSF000071 1 54 1.5E-28 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 SUPERFAMILY SSF57802 1 53 5.05E-25 T 23-10-2018 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 PRINTS PR00163 Rubredoxin signature 3 19 5.4E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSIB_1895 24aec61ea069c58906bc9e005df8217d 54 PRINTS PR00163 Rubredoxin signature 33 49 5.4E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSIB_1540 3aae1318a22e3c7de5949bf2d127adb3 130 Gene3D G3DSA:1.10.10.10 3 57 1.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1540 3aae1318a22e3c7de5949bf2d127adb3 130 SUPERFAMILY SSF88659 16 48 1.48E-6 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 SUPERFAMILY SSF116726 109 192 1.96E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 SUPERFAMILY SSF109755 5 122 1.01E-19 T 23-10-2018 TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 Pfam PF01895 PhoU domain 19 101 4.6E-13 T 23-10-2018 IPR026022 PhoU domain TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 Pfam PF02080 TrkA-C domain 124 191 3.8E-13 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 Gene3D G3DSA:3.30.70.1450 118 205 5.1E-25 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSIB_0154 9aa1b20dc50cbadfb713d20ad7639b1d 205 Gene3D G3DSA:1.20.58.220 1 117 1.1E-28 T 23-10-2018 IPR038078 PhoU-like domain superfamily TSIB_0025 61365a477d5a57ae7436ce4c5805fe55 184 SUPERFAMILY SSF50324 8 183 1.02E-66 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSIB_0025 61365a477d5a57ae7436ce4c5805fe55 184 Gene3D G3DSA:3.90.80.10 3 184 1.5E-72 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSIB_0025 61365a477d5a57ae7436ce4c5805fe55 184 Pfam PF00719 Inorganic pyrophosphatase 28 179 4.8E-56 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSIB_0025 61365a477d5a57ae7436ce4c5805fe55 184 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 23 179 35.708 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSIB_0025 61365a477d5a57ae7436ce4c5805fe55 184 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 74 80 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSIB_1836 d49af3957029db8b2bec3082f532545e 165 Gene3D G3DSA:3.40.50.620 15 162 8.3E-43 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_1836 d49af3957029db8b2bec3082f532545e 165 SUPERFAMILY SSF52374 13 155 3.07E-20 T 23-10-2018 TSIB_1836 d49af3957029db8b2bec3082f532545e 165 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 15 165 33.301 T 23-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSIB_1836 d49af3957029db8b2bec3082f532545e 165 Pfam PF01467 Cytidylyltransferase-like 18 154 3.3E-15 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_1836 d49af3957029db8b2bec3082f532545e 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 71 5.6E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSIB_0017 8af407e52d4a57a97ba5540086fe6fa7 183 Gene3D G3DSA:3.30.460.10 71 173 8.1E-12 T 23-10-2018 TSIB_0017 8af407e52d4a57a97ba5540086fe6fa7 183 SUPERFAMILY SSF81301 99 179 2.4E-12 T 23-10-2018 TSIB_0017 8af407e52d4a57a97ba5540086fe6fa7 183 Pfam PF01909 Nucleotidyltransferase domain 102 158 1.8E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1440 24b6bbb43cd4cb7238ef4a9d7e3b3512 491 Pfam PF09847 Membrane protein of 12 TMs 40 485 1.9E-61 T 23-10-2018 IPR018646 Membrane protein of 12 TMs TSIB_1440 24b6bbb43cd4cb7238ef4a9d7e3b3512 491 PIRSF PIRSF018875 1 490 3.1E-60 T 23-10-2018 IPR018646 Membrane protein of 12 TMs TSIB_1066 f13f2b27b5a0cc2449bdb4e7a3e8c1cb 380 TIGRFAM TIGR00260 thrC: threonine synthase 57 358 3.9E-57 T 23-10-2018 IPR004450 Threonine synthase-like TSIB_1066 f13f2b27b5a0cc2449bdb4e7a3e8c1cb 380 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 353 2.9E-74 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1066 f13f2b27b5a0cc2449bdb4e7a3e8c1cb 380 SUPERFAMILY SSF53686 2 364 7.2E-89 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_1066 f13f2b27b5a0cc2449bdb4e7a3e8c1cb 380 Gene3D G3DSA:3.40.50.1100 44 358 2.2E-106 T 23-10-2018 TSIB_1066 f13f2b27b5a0cc2449bdb4e7a3e8c1cb 380 Gene3D G3DSA:3.40.50.1100 93 188 2.2E-106 T 23-10-2018 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 Gene3D G3DSA:1.10.10.10 2 106 3.1E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 1.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 1.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 59 1.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 SMART SM00418 27 105 9.6E-23 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 SUPERFAMILY SSF46785 17 104 1.09E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1263 d8207d9c61069b58ac36021fd47702fe 108 Pfam PF01022 Bacterial regulatory protein, arsR family 34 78 4.1E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 1.5E-16 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 45.064 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 PRINTS PR00094 Adenylate kinase signature 79 95 1.6E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 PRINTS PR00094 Adenylate kinase signature 175 189 1.6E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 PRINTS PR00094 Adenylate kinase signature 32 46 1.6E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 PRINTS PR00094 Adenylate kinase signature 4 17 1.6E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 PRINTS PR00094 Adenylate kinase signature 158 173 1.6E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 Pfam PF00406 Adenylate kinase 5 188 2.1E-39 T 23-10-2018 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 SUPERFAMILY SSF52540 1 212 1.09E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 Gene3D G3DSA:3.40.50.300 1 220 1.4E-72 T 23-10-2018 TSIB_0835 eea1fcd3026f87fc4c73aa8d7c4c1b75 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 3.9E-71 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 Gene3D G3DSA:3.30.230.70 4 244 5.6E-79 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 SUPERFAMILY SSF55666 153 240 2.62E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 3.4E-17 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 Pfam PF01138 3' exoribonuclease family, domain 1 24 153 5.7E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 SUPERFAMILY SSF54211 9 179 5.57E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 60.721 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TSIB_1349 e264b079d3fc6b49a8edcf17750ce937 246 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 8 237 4.1E-120 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 SUPERFAMILY SSF52343 115 249 5.18E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 3.4E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 PIRSF PIRSF006816 1 256 2.6E-41 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 SUPERFAMILY SSF63380 3 91 2.62E-12 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 Gene3D G3DSA:3.40.50.80 99 204 4.7E-12 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSIB_1464 9aafed29813e9b801e3792dc902fb257 282 Gene3D G3DSA:2.40.30.10 1 91 8.7E-11 T 23-10-2018 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.293 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 420 8.1E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.8E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.8E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.8E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.8E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.8E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 Gene3D G3DSA:1.10.287.40 1 107 7.9E-33 T 23-10-2018 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 437 1.3E-161 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 SUPERFAMILY SSF55681 158 446 5.19E-89 T 23-10-2018 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 Gene3D G3DSA:3.30.930.10 108 455 3.9E-135 T 23-10-2018 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 SUPERFAMILY SSF46589 1 115 1.83E-26 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 2.5E-25 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TSIB_1397 0fd6b6d69d218372d3c7e230c0401930 455 PIRSF PIRSF001529 1 447 5.3E-155 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSIB_1722 ce7d4fdb3a75832a1c56d64a98c8dc26 173 Pfam PF00210 Ferritin-like domain 7 142 8.8E-47 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSIB_1722 ce7d4fdb3a75832a1c56d64a98c8dc26 173 SUPERFAMILY SSF47240 1 160 2.92E-61 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1722 ce7d4fdb3a75832a1c56d64a98c8dc26 173 Gene3D G3DSA:1.20.1260.10 1 173 4.6E-58 T 23-10-2018 IPR012347 Ferritin-like TSIB_0883 8e35b4575019b9a0bb6594baa374c8b9 304 Pfam PF00288 GHMP kinases N terminal domain 92 151 3.7E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_0883 8e35b4575019b9a0bb6594baa374c8b9 304 SUPERFAMILY SSF54211 1 158 1.67E-12 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_0883 8e35b4575019b9a0bb6594baa374c8b9 304 PIRSF PIRSF016896 1 297 8.2E-88 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 TSIB_0883 8e35b4575019b9a0bb6594baa374c8b9 304 Gene3D G3DSA:3.30.230.10 28 157 1.4E-5 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 SUPERFAMILY SSF53383 30 443 2.34E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 Pfam PF00202 Aminotransferase class-III 34 442 4.4E-114 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 Gene3D G3DSA:3.40.640.10 72 341 1.5E-151 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 PIRSF PIRSF000521 138 445 1.3E-48 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 PIRSF PIRSF000521 1 144 7.6E-14 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSIB_1150 64e8251ee3c66050202eb3f240d77901 447 Gene3D G3DSA:3.90.1150.10 14 440 1.5E-151 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 Gene3D G3DSA:3.40.190.10 49 363 1.7E-104 T 23-10-2018 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 46 375 2.2E-121 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 SUPERFAMILY SSF53850 46 375 1.09E-86 T 23-10-2018 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 Gene3D G3DSA:3.40.190.10 125 311 1.7E-104 T 23-10-2018 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 PIRSF PIRSF002756 1 377 1.2E-111 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TSIB_1880 52d8842267db01be6f67df529c9ab548 377 Pfam PF12849 PBP superfamily domain 40 345 2.5E-57 T 23-10-2018 IPR024370 PBP domain TSIB_0935 0184feff0170bcbd4fc6c15426360b86 455 SUPERFAMILY SSF111283 1 449 1.44E-109 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSIB_0935 0184feff0170bcbd4fc6c15426360b86 455 PIRSF PIRSF004919 1 454 6.6E-163 T 23-10-2018 IPR025502 TldD TSIB_0935 0184feff0170bcbd4fc6c15426360b86 455 Pfam PF01523 Putative modulator of DNA gyrase 21 309 2.0E-60 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSIB_0935 0184feff0170bcbd4fc6c15426360b86 455 Gene3D G3DSA:3.30.2290.10 1 190 3.4E-11 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSIB_1876 d7efae609fd14675746f54ec7638762b 253 SMART SM00382 29 225 7.5E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1876 d7efae609fd14675746f54ec7638762b 253 SUPERFAMILY SSF52540 4 240 1.39E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1876 d7efae609fd14675746f54ec7638762b 253 Gene3D G3DSA:3.40.50.300 3 252 1.8E-70 T 23-10-2018 TSIB_1876 d7efae609fd14675746f54ec7638762b 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1876 d7efae609fd14675746f54ec7638762b 253 Pfam PF00005 ABC transporter 21 178 1.4E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1888 83e8825e0200636f90f67dfd4364f118 209 Gene3D G3DSA:1.10.3720.10 9 204 4.8E-28 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1888 83e8825e0200636f90f67dfd4364f118 209 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 194 7.0E-24 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1888 83e8825e0200636f90f67dfd4364f118 209 SUPERFAMILY SSF161098 12 192 1.96E-35 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 PIRSF PIRSF005962 1 380 9.7E-138 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 Pfam PF07687 Peptidase dimerisation domain 177 272 1.2E-11 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 SUPERFAMILY SSF53187 5 378 7.18E-87 T 23-10-2018 TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 1.8E-121 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 Pfam PF01546 Peptidase family M20/M25/M40 68 370 1.9E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 SUPERFAMILY SSF55031 177 285 4.84E-31 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 Gene3D G3DSA:3.40.630.10 14 365 4.6E-147 T 23-10-2018 TSIB_0268 3746748da8d4d35597daa1a5bdef4c2b 380 Gene3D G3DSA:3.30.70.360 176 290 4.6E-147 T 23-10-2018 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 Gene3D G3DSA:3.40.50.12240 2 464 4.9E-195 T 23-10-2018 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 355 5.4E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 10 465 3.2E-267 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 SUPERFAMILY SSF52540 84 360 1.06E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 SUPERFAMILY SSF47917 368 425 1.6E-8 T 23-10-2018 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 346 355 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 8 464 62.415 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 PIRSF PIRSF039114 1 467 2.3E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1791 348f8ff21acb2517ffea7ebaa2581d33 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 80 1.9E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSIB_0872 daaf96973e267b2b90cd87bf753de78f 485 Pfam PF14010 Phosphoenolpyruvate carboxylase 11 485 1.7E-178 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSIB_0872 daaf96973e267b2b90cd87bf753de78f 485 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 10 485 38.523 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSIB_0872 daaf96973e267b2b90cd87bf753de78f 485 SUPERFAMILY SSF51621 101 420 2.31E-36 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSIB_0872 daaf96973e267b2b90cd87bf753de78f 485 PIRSF PIRSF006677 8 485 2.5E-182 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSIB_0872 daaf96973e267b2b90cd87bf753de78f 485 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 11 459 1.5E-184 T 23-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSIB_1908 650cd9210966a01feeefd9097768a12e 193 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 1.2E-18 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1908 650cd9210966a01feeefd9097768a12e 193 SUPERFAMILY SSF56770 6 155 2.35E-49 T 23-10-2018 TSIB_1908 650cd9210966a01feeefd9097768a12e 193 Gene3D G3DSA:3.40.50.12280 3 163 1.9E-47 T 23-10-2018 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 Pfam PF01866 Putative diphthamide synthesis protein 31 324 5.0E-77 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 7 318 6.0E-91 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 Gene3D G3DSA:3.40.50.11860 217 318 1.8E-34 T 23-10-2018 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 Gene3D G3DSA:3.40.50.11840 10 104 2.1E-30 T 23-10-2018 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 PIRSF PIRSF004967 1 340 2.1E-85 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 Gene3D G3DSA:3.40.50.11850 105 213 1.7E-41 T 23-10-2018 TSIB_0075 1ab0b68d9e3e4885d81d454bec6acd57 350 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 22 329 1.4E-111 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 TSIB_1072 cb3cca8e75a074b2b29a911d4fa035bf 273 Pfam PF00583 Acetyltransferase (GNAT) family 26 126 1.9E-11 T 23-10-2018 IPR000182 GNAT domain TSIB_1072 cb3cca8e75a074b2b29a911d4fa035bf 273 Gene3D G3DSA:3.40.630.30 3 204 4.1E-33 T 23-10-2018 TSIB_1072 cb3cca8e75a074b2b29a911d4fa035bf 273 SUPERFAMILY SSF55729 1 134 3.43E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 Gene3D G3DSA:3.10.580.10 435 562 5.8E-18 T 23-10-2018 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 SUPERFAMILY SSF81340 10 430 5.23E-95 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 Pfam PF00571 CBS domain 443 495 1.6E-4 T 23-10-2018 IPR000644 CBS domain TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 Pfam PF00571 CBS domain 517 560 2.9E-6 T 23-10-2018 IPR000644 CBS domain TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 Gene3D G3DSA:1.10.3080.10 2 432 6.4E-92 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 SUPERFAMILY SSF54631 437 562 9.03E-22 T 23-10-2018 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 SMART SM00116 450 498 1.2 T 23-10-2018 IPR000644 CBS domain TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 SMART SM00116 512 562 0.023 T 23-10-2018 IPR000644 CBS domain TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 Pfam PF00654 Voltage gated chloride channel 68 410 2.2E-80 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 PRINTS PR00762 Chloride channel signature 325 345 1.9E-16 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 PRINTS PR00762 Chloride channel signature 160 179 1.9E-16 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 PRINTS PR00762 Chloride channel signature 360 376 1.9E-16 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSIB_0247 f204f00b0374b356d9b6f0f530ba2b45 572 PRINTS PR00762 Chloride channel signature 80 97 1.9E-16 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 8.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 8.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 8.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 Gene3D G3DSA:1.10.10.10 1 59 6.4E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 SUPERFAMILY SSF54909 67 152 4.02E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 Pfam PF01037 Lrp/AsnC ligand binding domain 84 142 2.5E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 4.3E-13 T 23-10-2018 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 Gene3D G3DSA:3.30.70.920 60 153 1.0E-23 T 23-10-2018 TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 SUPERFAMILY SSF46785 7 67 3.38E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0984 ed8b4a50df2e4dd4c82063f1c1e0be0a 159 SMART SM00344 7 113 1.1E-36 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1498 2b7604cf969956f940244f56e495a624 162 SUPERFAMILY SSF51306 28 126 4.53E-8 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSIB_1498 2b7604cf969956f940244f56e495a624 162 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 11 131 1.5E-27 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TSIB_1498 2b7604cf969956f940244f56e495a624 162 Pfam PF00717 Peptidase S24-like 33 91 6.6E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSIB_0539 2b18dd0cece89f9f03ff9288c5c64a3a 474 PIRSF PIRSF004919 1 474 8.9E-152 T 23-10-2018 IPR025502 TldD TSIB_0539 2b18dd0cece89f9f03ff9288c5c64a3a 474 SUPERFAMILY SSF111283 1 470 1.14E-101 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSIB_0539 2b18dd0cece89f9f03ff9288c5c64a3a 474 Gene3D G3DSA:3.30.2290.10 2 199 2.3E-21 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSIB_0539 2b18dd0cece89f9f03ff9288c5c64a3a 474 Pfam PF01523 Putative modulator of DNA gyrase 21 327 1.3E-55 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSIB_0833 249597afb400e67504d552379a4f24ea 507 SUPERFAMILY SSF81324 421 506 5.76E-15 T 23-10-2018 TSIB_0833 249597afb400e67504d552379a4f24ea 507 Gene3D G3DSA:1.10.287.70 412 507 9.7E-14 T 23-10-2018 TSIB_0833 249597afb400e67504d552379a4f24ea 507 Pfam PF07885 Ion channel 433 506 9.1E-13 T 23-10-2018 IPR013099 Potassium channel domain TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 7.6E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 SMART SM00418 11 110 7.2E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 SUPERFAMILY SSF46785 1 112 7.29E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 Gene3D G3DSA:1.10.10.10 1 84 9.0E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 4.5E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1968 f2b584506ba29c7652a92bd1a6de46da 186 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 4.5E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 SUPERFAMILY SSF82866 147 364 1.23E-39 T 23-10-2018 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 SUPERFAMILY SSF82866 544 740 8.11E-36 T 23-10-2018 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 Pfam PF03176 MMPL family 524 737 2.7E-23 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 Pfam PF03176 MMPL family 44 402 4.3E-33 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 Gene3D G3DSA:1.20.1640.10 584 748 6.7E-13 T 23-10-2018 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 Gene3D G3DSA:1.20.1640.10 188 374 2.2E-21 T 23-10-2018 TSIB_1847 5bde1dc70001c5fa3b7ec7a96277c025 748 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 11 737 1.1E-230 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 SUPERFAMILY SSF55608 154 271 4.04E-11 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 Pfam PF14528 LAGLIDADG-like domain 164 258 1.5E-14 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 Pfam PF14528 LAGLIDADG-like domain 75 141 1.7E-8 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 PRINTS PR00379 Intein signature 199 214 7.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 PRINTS PR00379 Intein signature 74 86 7.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 PRINTS PR00379 Intein signature 165 177 7.2E-6 T 23-10-2018 IPR006142 Intein GO:0016539 TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 Gene3D G3DSA:3.10.28.10 71 237 2.9E-16 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1946 553c587295c9a131b580442ae8dd8ad0 313 SUPERFAMILY SSF55608 68 147 9.72E-12 T 23-10-2018 IPR027434 Homing endonuclease TSIB_1997 d2bf677aaa451c5111ac827a99f93a02 153 PIRSF PIRSF018748 1 153 3.4E-50 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TSIB_1997 d2bf677aaa451c5111ac827a99f93a02 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 9 137 3.5E-31 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TSIB_1119 d1827be74c6507c280f85fbdf5df0e9a 344 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 23-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSIB_1119 d1827be74c6507c280f85fbdf5df0e9a 344 SUPERFAMILY SSF53633 3 273 2.75E-56 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1119 d1827be74c6507c280f85fbdf5df0e9a 344 Pfam PF00696 Amino acid kinase family 3 259 2.3E-43 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSIB_1119 d1827be74c6507c280f85fbdf5df0e9a 344 TIGRFAM TIGR02078 AspKin_pair: putative Pyrococcus aspartate kinase subunit 6 334 5.3E-96 T 23-10-2018 IPR011819 Pyrococcus aspartate kinase subunit, putative TSIB_1119 d1827be74c6507c280f85fbdf5df0e9a 344 Gene3D G3DSA:3.40.1160.10 4 274 5.0E-65 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1878 b60bc097e793e9aec3ca575da48c560a 313 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 16 307 8.8E-86 T 23-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TSIB_1878 b60bc097e793e9aec3ca575da48c560a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 306 3.5E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1878 b60bc097e793e9aec3ca575da48c560a 313 Gene3D G3DSA:1.10.3720.10 67 310 1.5E-26 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1878 b60bc097e793e9aec3ca575da48c560a 313 SUPERFAMILY SSF161098 18 298 1.12E-27 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1468 5d62f60948e3acb958427e33607663d2 379 Gene3D G3DSA:3.40.50.920 265 378 1.2E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1468 5d62f60948e3acb958427e33607663d2 379 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 251 1.4E-79 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1468 5d62f60948e3acb958427e33607663d2 379 SUPERFAMILY SSF52518 6 260 4.52E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1468 5d62f60948e3acb958427e33607663d2 379 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 276 370 4.9E-21 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TSIB_1468 5d62f60948e3acb958427e33607663d2 379 SUPERFAMILY SSF52922 268 375 2.75E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1468 5d62f60948e3acb958427e33607663d2 379 Gene3D G3DSA:3.40.50.970 1 193 4.1E-81 T 23-10-2018 TSIB_0856 a3211e93f0381f8a937289aff36ffcf4 242 Gene3D G3DSA:3.40.50.10310 5 241 1.1E-63 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSIB_0856 a3211e93f0381f8a937289aff36ffcf4 242 SUPERFAMILY SSF102215 5 241 1.96E-60 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSIB_0856 a3211e93f0381f8a937289aff36ffcf4 242 Pfam PF02633 Creatinine amidohydrolase 9 237 3.8E-60 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 Gene3D G3DSA:3.30.470.20 201 429 1.4E-75 T 23-10-2018 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 Gene3D G3DSA:3.30.1490.20 129 200 6.3E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 Gene3D G3DSA:3.40.50.20 1 128 2.4E-57 T 23-10-2018 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 48.555 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 SUPERFAMILY SSF56059 118 325 1.45E-51 T 23-10-2018 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 SUPERFAMILY SSF51246 339 410 7.06E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 411 8.0E-187 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 Pfam PF02222 ATP-grasp domain 127 303 5.4E-55 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TSIB_0063 c5d3d50167bfd231a8e1b00f2815ba4e 429 SUPERFAMILY SSF52440 8 115 1.22E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSIB_1362 737ae7d656b28ca335cb0ec0c8b40f01 183 SUPERFAMILY SSF52768 6 149 1.35E-41 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TSIB_1362 737ae7d656b28ca335cb0ec0c8b40f01 183 Gene3D G3DSA:3.40.800.10 4 158 2.8E-45 T 23-10-2018 TSIB_1362 737ae7d656b28ca335cb0ec0c8b40f01 183 Pfam PF00491 Arginase family 7 140 4.9E-38 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TSIB_1475 df8708e1e1a67e0cd814e843785777a0 261 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 261 31.778 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSIB_1475 df8708e1e1a67e0cd814e843785777a0 261 Pfam PF01975 Survival protein SurE 4 194 2.6E-54 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSIB_1475 df8708e1e1a67e0cd814e843785777a0 261 SUPERFAMILY SSF64167 3 257 2.09E-69 T 23-10-2018 TSIB_1475 df8708e1e1a67e0cd814e843785777a0 261 Gene3D G3DSA:3.40.1210.10 2 260 1.8E-83 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSIB_1475 df8708e1e1a67e0cd814e843785777a0 261 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 247 1.9E-69 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSIB_1684 a5769ee3889e0c2fc651501cf68ffc77 338 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 8.7E-22 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_1684 a5769ee3889e0c2fc651501cf68ffc77 338 SUPERFAMILY SSF159071 249 337 1.31E-20 T 23-10-2018 TSIB_1684 a5769ee3889e0c2fc651501cf68ffc77 338 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 337 3.0E-45 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TSIB_1684 a5769ee3889e0c2fc651501cf68ffc77 338 SUPERFAMILY SSF46785 4 84 6.83E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1684 a5769ee3889e0c2fc651501cf68ffc77 338 Gene3D G3DSA:1.10.10.10 3 103 8.7E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1377 afade99da0eed69b99f574f235a0cda3 293 Hamap MF_02040 Iron-sulfur cluster carrier protein. 25 283 36.839 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TSIB_1377 afade99da0eed69b99f574f235a0cda3 293 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 31 282 1.6E-95 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TSIB_1377 afade99da0eed69b99f574f235a0cda3 293 ProSitePatterns PS01215 Mrp family signature. 147 163 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 TSIB_1377 afade99da0eed69b99f574f235a0cda3 293 Gene3D G3DSA:3.40.50.300 18 282 5.5E-82 T 23-10-2018 TSIB_1377 afade99da0eed69b99f574f235a0cda3 293 SUPERFAMILY SSF52540 19 267 1.02E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 5 420 4.4E-148 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 5 104 1.3E-25 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 SUPERFAMILY SSF56059 106 323 4.07E-48 T 23-10-2018 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 SUPERFAMILY SSF51246 330 420 4.0E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 SUPERFAMILY SSF52440 4 105 3.88E-26 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 SMART SM01210 331 421 3.6E-19 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Gene3D G3DSA:3.30.470.20 192 331 5.9E-47 T 23-10-2018 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 105 299 5.4E-60 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Gene3D G3DSA:3.90.600.10 332 421 1.4E-9 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 SMART SM01209 105 299 1.0E-93 T 23-10-2018 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 293 300 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 5 421 36.685 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 419 1.0E-12 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Gene3D G3DSA:3.30.1490.20 125 190 8.1E-15 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0060 defc3c8480c560dc0f97a9a5e53a465c 435 Gene3D G3DSA:3.40.50.20 6 97 3.5E-23 T 23-10-2018 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 PIRSF PIRSF002144 1 133 3.4E-39 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 SUPERFAMILY SSF54570 34 117 2.88E-30 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.396 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 Gene3D G3DSA:3.30.860.20 2 133 4.7E-52 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 4.6E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 4.6E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 4.6E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 Pfam PF00203 Ribosomal protein S19 35 116 1.3E-34 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0292 6ea768e1e2a416c69e98536789595571 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 1.0E-65 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 1.3E-46 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 Gene3D G3DSA:2.40.50.1000 1 111 2.6E-39 T 23-10-2018 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 SUPERFAMILY SSF50249 29 108 3.17E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 32.856 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 1.4E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 1.4E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 1.4E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 8.0E-21 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0298 b0c0d611db6fca683f27df264f9a076e 111 Pfam PF00366 Ribosomal protein S17 35 102 4.0E-24 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.021 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 Pfam PF01070 FMN-dependent dehydrogenase 13 105 1.1E-9 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 Pfam PF01070 FMN-dependent dehydrogenase 186 346 9.0E-17 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 1.0E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 Gene3D G3DSA:3.20.20.70 10 373 1.6E-128 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 SUPERFAMILY SSF51395 33 367 9.94E-82 T 23-10-2018 TSIB_1231 8af5ae59ce3fd10407f327abeb03ebdc 374 PIRSF PIRSF003314 7 363 1.0E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TSIB_0911 39d029b737682b97b9e3cf0cdda15d0c 398 SUPERFAMILY SSF53383 14 392 4.98E-54 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0911 39d029b737682b97b9e3cf0cdda15d0c 398 Gene3D G3DSA:3.90.1150.10 14 387 1.3E-60 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0911 39d029b737682b97b9e3cf0cdda15d0c 398 Pfam PF00266 Aminotransferase class-V 16 387 6.9E-29 T 23-10-2018 IPR000192 Aminotransferase class V domain TSIB_0911 39d029b737682b97b9e3cf0cdda15d0c 398 Gene3D G3DSA:3.40.640.10 26 299 1.3E-60 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1286 927c153b0afe53278fd1461f3bc802f1 148 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 8 134 7.3E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1286 927c153b0afe53278fd1461f3bc802f1 148 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 21 131 2.3E-28 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1286 927c153b0afe53278fd1461f3bc802f1 148 SUPERFAMILY SSF56770 7 137 2.75E-55 T 23-10-2018 TSIB_1286 927c153b0afe53278fd1461f3bc802f1 148 Gene3D G3DSA:3.40.50.12280 2 148 6.0E-56 T 23-10-2018 TSIB_1606 d4929c1bd61844a5e6ee41eef981301b 139 Pfam PF04027 Domain of unknown function (DUF371) 6 137 4.1E-51 T 23-10-2018 IPR007171 Protein of unknown function DUF371 TSIB_1606 d4929c1bd61844a5e6ee41eef981301b 139 Gene3D G3DSA:2.60.120.630 1 139 3.7E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 SMART SM00849 19 207 6.9E-4 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 SUPERFAMILY SSF56281 3 297 7.51E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 Hamap MF_01818 Ribonuclease BN [rbn]. 2 296 34.193 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 294 5.6E-100 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 Pfam PF12706 Beta-lactamase superfamily domain 37 152 1.1E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 Pfam PF12706 Beta-lactamase superfamily domain 197 263 4.3E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0827 db0ecfa43f75bba5d982a8e2794c0f23 306 Gene3D G3DSA:3.60.15.10 1 296 7.2E-85 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0005 2e27c54171f72df7513f40071ec34528 332 Gene3D G3DSA:3.90.550.10 2 220 1.0E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0005 2e27c54171f72df7513f40071ec34528 332 Pfam PF00535 Glycosyl transferase family 2 8 169 2.1E-35 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_0005 2e27c54171f72df7513f40071ec34528 332 SUPERFAMILY SSF53448 6 261 7.16E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1824 d6f66628a5c8ebacf0eeff06421daf05 209 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 5 187 9.5E-46 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TSIB_1442 e0b5888594984c86139808fca255f98f 517 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 14 511 4.2E-95 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein TSIB_1442 e0b5888594984c86139808fca255f98f 517 Gene3D G3DSA:3.20.20.20 173 328 4.1E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_1442 e0b5888594984c86139808fca255f98f 517 SUPERFAMILY SSF51717 167 395 2.49E-25 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_0211 13b945af4f73343ae21813e8c8bd98e6 144 Gene3D G3DSA:3.10.330.10 1 77 1.6E-31 T 23-10-2018 TSIB_0211 13b945af4f73343ae21813e8c8bd98e6 144 Gene3D G3DSA:2.40.10.360 80 144 1.2E-27 T 23-10-2018 TSIB_0211 13b945af4f73343ae21813e8c8bd98e6 144 SMART SM01072 12 74 2.0E-7 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_0211 13b945af4f73343ae21813e8c8bd98e6 144 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 13 70 4.9E-7 T 23-10-2018 IPR004201 CDC48, domain 2 TSIB_0211 13b945af4f73343ae21813e8c8bd98e6 144 SUPERFAMILY SSF54585 2 76 1.86E-13 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TSIB_0682 80c527e3545768918814cffe7742d68d 154 Pfam PF01986 Domain of unknown function DUF123 25 110 6.0E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 TSIB_0682 80c527e3545768918814cffe7742d68d 154 SMART SM00465 18 113 5.9E-7 T 23-10-2018 IPR000305 GIY-YIG endonuclease TSIB_2047 6e0912bf90b6b904db536cfe1fd2d9b0 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 1.6E-77 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSIB_2047 6e0912bf90b6b904db536cfe1fd2d9b0 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 178 3.0E-86 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSIB_2047 6e0912bf90b6b904db536cfe1fd2d9b0 185 SUPERFAMILY SSF51182 4 182 1.42E-80 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_2047 6e0912bf90b6b904db536cfe1fd2d9b0 185 Gene3D G3DSA:2.60.120.10 3 184 2.4E-77 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_2047 6e0912bf90b6b904db536cfe1fd2d9b0 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 3.0E-88 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSIB_0531 4666e203c62107e9621104ac57ea6599 182 Pfam PF04434 SWIM zinc finger 49 71 1.9E-6 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TSIB_0973 20c064ebfe4055e414a2ac55c1a71f0c 190 Pfam PF13238 AAA domain 9 122 1.4E-20 T 23-10-2018 TSIB_0973 20c064ebfe4055e414a2ac55c1a71f0c 190 Hamap MF_00039 Putative adenylate kinase. 7 166 25.258 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSIB_0973 20c064ebfe4055e414a2ac55c1a71f0c 190 Gene3D G3DSA:3.40.50.300 4 186 8.7E-58 T 23-10-2018 TSIB_0973 20c064ebfe4055e414a2ac55c1a71f0c 190 SUPERFAMILY SSF52540 6 161 5.14E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0834 510b06901802b3d284a27abebed2047c 132 SMART SM00470 34 118 4.3E-6 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TSIB_0834 510b06901802b3d284a27abebed2047c 132 Gene3D G3DSA:3.90.1530.10 32 119 6.0E-9 T 23-10-2018 TSIB_0834 510b06901802b3d284a27abebed2047c 132 SUPERFAMILY SSF110849 35 107 9.55E-13 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSIB_0834 510b06901802b3d284a27abebed2047c 132 Pfam PF02195 ParB-like nuclease domain 36 103 1.7E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TSIB_0308 cc277779404de599483668e630673ad3 200 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 191 44.778 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 Gene3D G3DSA:3.30.420.100 1 197 3.0E-73 T 23-10-2018 TSIB_0308 cc277779404de599483668e630673ad3 200 PRINTS PR00058 Ribosomal protein L5 signature 103 122 3.4E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 PRINTS PR00058 Ribosomal protein L5 signature 1 12 3.4E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 PRINTS PR00058 Ribosomal protein L5 signature 123 142 3.4E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 97 3.1E-15 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 101 134 9.4E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 Pfam PF14204 Ribosomal L18 C-terminal region 142 194 3.5E-11 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0308 cc277779404de599483668e630673ad3 200 SUPERFAMILY SSF53137 2 194 2.18E-63 T 23-10-2018 TSIB_1512 a53dd8c214b80e9b719ff04efc4e0055 174 Gene3D G3DSA:2.160.10.10 1 174 4.9E-63 T 23-10-2018 TSIB_1512 a53dd8c214b80e9b719ff04efc4e0055 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 2.0E-8 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_1512 a53dd8c214b80e9b719ff04efc4e0055 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 0.0011 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_1512 a53dd8c214b80e9b719ff04efc4e0055 174 SUPERFAMILY SSF51161 4 168 2.77E-52 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 3.0E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 Pfam PF14697 4Fe-4S dicluster domain 64 117 1.6E-10 T 23-10-2018 TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 SUPERFAMILY SSF52540 2 293 3.66E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 SUPERFAMILY SSF54862 64 137 3.63E-18 T 23-10-2018 TSIB_0690 32f57ed28bbbd5c99a92bb860ea5092e 295 Gene3D G3DSA:3.30.70.20 67 116 2.4E-12 T 23-10-2018 TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 Gene3D G3DSA:1.20.1510.10 9 203 1.6E-46 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 280 1.5E-11 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 SUPERFAMILY SSF161111 9 204 4.32E-56 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 SUPERFAMILY SSF160240 207 280 1.05E-15 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 Gene3D G3DSA:3.30.70.1350 204 282 2.9E-8 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 282 1.2E-90 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSIB_1697 25d348ccefba5e9dd76c29f4df5d0f36 296 Pfam PF01545 Cation efflux family 14 203 1.8E-44 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 SUPERFAMILY SSF50993 21 374 7.85E-41 T 23-10-2018 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 Pfam PF00326 Prolyl oligopeptidase family 434 638 7.4E-56 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 SUPERFAMILY SSF53474 392 637 2.4E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 Gene3D G3DSA:2.130.10.120 70 384 8.1E-143 T 23-10-2018 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 Gene3D G3DSA:3.40.50.1820 22 633 8.1E-143 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 497 517 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 571 593 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 552 567 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 471 490 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 417 435 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 443 467 1.8E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TSIB_0169 45b805a78ec643d495d21acc3cf600c4 641 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 22 374 1.9E-23 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TSIB_1493 60388b9babdc5e9f411af992a9b10610 231 Pfam PF12705 PD-(D/E)XK nuclease superfamily 79 229 2.0E-7 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TSIB_1493 60388b9babdc5e9f411af992a9b10610 231 Gene3D G3DSA:3.90.320.10 11 231 2.9E-20 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSIB_1277 ce8c2efa722232c390df1d1e5e35e69d 260 Gene3D G3DSA:3.30.2010.10 47 132 1.0E-16 T 23-10-2018 TSIB_1277 ce8c2efa722232c390df1d1e5e35e69d 260 Pfam PF01435 Peptidase family M48 57 245 1.8E-23 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSIB_1710 c08353e1b76e1f0d67e1c8aa2b7fae4b 97 Pfam PF09851 Short C-terminal domain 69 95 3.2E-10 T 23-10-2018 IPR018649 SHOCT domain TSIB_1356 cadd1cff497b3b7d42bd002b5813364c 184 SMART SM00507 30 83 2.0E-9 T 23-10-2018 IPR003615 HNH nuclease TSIB_1356 cadd1cff497b3b7d42bd002b5813364c 184 Pfam PF01844 HNH endonuclease 43 84 1.7E-12 T 23-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 TSIB_1356 cadd1cff497b3b7d42bd002b5813364c 184 Gene3D G3DSA:3.30.40.60 3 152 5.2E-12 T 23-10-2018 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 Pfam PF01061 ABC-2 type transporter 2 193 1.0E-37 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 PIRSF PIRSF006648 1 231 2.0E-66 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 1 226 4.3E-100 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 PRINTS PR00164 ABC-2 type transport system membrane protein signature 152 171 2.8E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 PRINTS PR00164 ABC-2 type transport system membrane protein signature 34 56 2.8E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 2.8E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_0214 ec9d27dd7daa37b5050fa4378d434f20 232 PRINTS PR00164 ABC-2 type transport system membrane protein signature 115 139 2.8E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSIB_1863 6feeb9245f7e4f763a97c3751af38efd 368 SUPERFAMILY SSF53807 25 316 4.32E-57 T 23-10-2018 TSIB_1863 6feeb9245f7e4f763a97c3751af38efd 368 Gene3D G3DSA:3.40.50.1980 21 167 2.2E-56 T 23-10-2018 TSIB_1863 6feeb9245f7e4f763a97c3751af38efd 368 Gene3D G3DSA:3.40.50.1980 169 364 4.3E-88 T 23-10-2018 TSIB_1863 6feeb9245f7e4f763a97c3751af38efd 368 Pfam PF01497 Periplasmic binding protein 47 289 1.6E-26 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TSIB_1796 c38b21dcfeb1e9cafc5d76376da77585 161 Pfam PF00137 ATP synthase subunit C 9 68 9.1E-13 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TSIB_1796 c38b21dcfeb1e9cafc5d76376da77585 161 Pfam PF00137 ATP synthase subunit C 96 154 3.1E-17 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TSIB_1796 c38b21dcfeb1e9cafc5d76376da77585 161 SUPERFAMILY SSF81333 88 155 3.01E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TSIB_1796 c38b21dcfeb1e9cafc5d76376da77585 161 Gene3D G3DSA:1.20.120.610 1 157 2.6E-40 T 23-10-2018 TSIB_1796 c38b21dcfeb1e9cafc5d76376da77585 161 SUPERFAMILY SSF81333 5 69 2.88E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TSIB_0778 24b9b2be4972b772fed0526ac336dadd 212 Gene3D G3DSA:3.40.50.11570 1 208 3.2E-59 T 23-10-2018 TSIB_0778 24b9b2be4972b772fed0526ac336dadd 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 204 9.4E-54 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_2043 5daf89194a0595ef59084a25ff19f39d 147 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 31 136 5.9E-12 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TSIB_1192 5c784e3504dad3059c4f7a347d4805b8 373 Pfam PF05763 Protein of unknown function (DUF835) 240 368 2.3E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_0276 13c985c62770753088a09d23c00e69e5 305 SUPERFAMILY SSF56235 16 298 9.77E-83 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_0276 13c985c62770753088a09d23c00e69e5 305 Gene3D G3DSA:3.60.20.30 175 303 1.5E-35 T 23-10-2018 TSIB_0276 13c985c62770753088a09d23c00e69e5 305 Pfam PF01112 Asparaginase 3 297 1.1E-90 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 Pfam PF07690 Major Facilitator Superfamily 22 409 1.3E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 Gene3D G3DSA:1.20.1720.10 17 245 2.9E-45 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 Gene3D G3DSA:1.20.1250.20 259 461 3.2E-22 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 337 357 2.2E-8 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.2E-8 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 2.2E-8 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 2.2E-8 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 2.2E-8 T 23-10-2018 TSIB_0718 31d7c3dd31225d0550cf5897d96b0370 463 SUPERFAMILY SSF103473 12 458 2.88E-68 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1923 eda668031739d234d01d539474c086fb 188 Pfam PF01944 Stage II sporulation protein M 13 182 8.5E-32 T 23-10-2018 IPR002798 Stage II sporulation protein M-like TSIB_0131 6c0a538a8b2239639f312f0ce9fd80d7 115 SUPERFAMILY SSF55620 1 113 3.89E-30 T 23-10-2018 TSIB_0131 6c0a538a8b2239639f312f0ce9fd80d7 115 PIRSF PIRSF006113 1 115 3.3E-32 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TSIB_0131 6c0a538a8b2239639f312f0ce9fd80d7 115 Gene3D G3DSA:3.30.479.10 1 115 1.6E-35 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TSIB_0131 6c0a538a8b2239639f312f0ce9fd80d7 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 2.8E-24 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 30 189 6.0E-67 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 Gene3D G3DSA:3.20.20.70 173 260 1.4E-5 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 5 257 3.2E-112 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 Pfam PF03437 BtpA family 5 255 1.9E-110 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 SUPERFAMILY SSF51366 11 251 7.77E-30 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSIB_0370 9b972ba27d3978de8b72c3dfeaab2511 260 PIRSF PIRSF005956 1 259 7.8E-98 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TSIB_0792 acfedb4de3113798dde59b350695337d 433 Hamap MF_00318 Enolase [eno]. 8 417 44.95 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 42 56 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 111 127 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 340 354 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 165 178 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 317 328 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PRINTS PR00148 Enolase signature 369 386 5.3E-48 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 9.5E-128 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 ProSitePatterns PS00164 Enolase signature. 340 353 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSIB_0792 acfedb4de3113798dde59b350695337d 433 SMART SM01193 10 138 1.2E-93 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 PIRSF PIRSF001400 6 430 2.4E-192 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 SUPERFAMILY SSF51604 142 431 7.21E-124 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSIB_0792 acfedb4de3113798dde59b350695337d 433 Pfam PF03952 Enolase, N-terminal domain 10 138 5.9E-59 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 SMART SM01192 143 431 6.1E-201 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 SUPERFAMILY SSF54826 9 143 4.38E-56 T 23-10-2018 TSIB_0792 acfedb4de3113798dde59b350695337d 433 Gene3D G3DSA:3.20.20.120 132 431 3.6E-130 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSIB_0792 acfedb4de3113798dde59b350695337d 433 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 10 428 2.6E-196 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSIB_0792 acfedb4de3113798dde59b350695337d 433 Gene3D G3DSA:3.30.390.10 4 130 6.6E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 SUPERFAMILY SSF52166 1 252 5.23E-71 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 2.7E-48 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 3.4E-114 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 43.786 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSIB_0289 105fdb6922eeae52cbc519fb6113d090 255 Gene3D G3DSA:3.40.1370.10 1 255 4.1E-97 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 Pfam PF00232 Glycosyl hydrolase family 1 123 486 1.1E-56 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 Pfam PF00232 Glycosyl hydrolase family 1 3 90 2.0E-7 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 Gene3D G3DSA:3.20.20.80 1 499 2.9E-143 T 23-10-2018 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 398 406 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 455 467 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 421 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 448 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 321 335 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 SUPERFAMILY SSF51445 3 491 4.1E-123 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 398 406 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site TSIB_0324 6930c7c5ff6d2629a259c6c3c14de237 501 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 5 19 - T 23-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TSIB_1086 339209be17abc7a09c6e27d5e2a8bf46 186 Gene3D G3DSA:1.20.120.1760 6 186 1.2E-50 T 23-10-2018 TSIB_1086 339209be17abc7a09c6e27d5e2a8bf46 186 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSIB_1086 339209be17abc7a09c6e27d5e2a8bf46 186 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 89 1.8E-14 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSIB_1577 dccbe7bb11ed81689520bb41b2f363de 370 SUPERFAMILY SSF53807 89 354 1.1E-67 T 23-10-2018 TSIB_1577 dccbe7bb11ed81689520bb41b2f363de 370 Gene3D G3DSA:3.40.50.1980 225 353 3.8E-39 T 23-10-2018 TSIB_1577 dccbe7bb11ed81689520bb41b2f363de 370 Pfam PF01497 Periplasmic binding protein 111 329 2.3E-43 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TSIB_1577 dccbe7bb11ed81689520bb41b2f363de 370 Gene3D G3DSA:3.40.50.1980 93 221 1.9E-29 T 23-10-2018 TSIB_1068 e78b1ad40955806c4138ab7827e1323f 109 Pfam PF01588 Putative tRNA binding domain 14 107 4.9E-26 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSIB_1068 e78b1ad40955806c4138ab7827e1323f 109 SUPERFAMILY SSF50249 8 108 8.57E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1068 e78b1ad40955806c4138ab7827e1323f 109 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 4 108 8.8E-36 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSIB_1068 e78b1ad40955806c4138ab7827e1323f 109 Gene3D G3DSA:2.40.50.140 1 109 8.3E-36 T 23-10-2018 TSIB_1523 ff14367a490b640f734c3d5e4e51a105 416 Pfam PF00374 Nickel-dependent hydrogenase 40 128 8.7E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_1523 ff14367a490b640f734c3d5e4e51a105 416 Pfam PF00374 Nickel-dependent hydrogenase 226 412 3.1E-18 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_1523 ff14367a490b640f734c3d5e4e51a105 416 Gene3D G3DSA:1.10.645.10 1 412 1.1E-99 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1523 ff14367a490b640f734c3d5e4e51a105 416 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 403 412 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSIB_1523 ff14367a490b640f734c3d5e4e51a105 416 SUPERFAMILY SSF56762 2 412 9.29E-95 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 446 2.6E-7 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 8 447 3.0E-164 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Gene3D G3DSA:3.40.120.10 6 152 5.8E-52 T 23-10-2018 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 SUPERFAMILY SSF53738 257 359 9.42E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 246 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 138 1.2E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 SUPERFAMILY SSF53738 155 254 1.02E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 251 2.1E-20 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 SUPERFAMILY SSF53738 7 177 1.65E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 SUPERFAMILY SSF55957 353 452 9.68E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 362 9.9E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 7 451 51.636 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Gene3D G3DSA:3.40.120.10 168 350 1.5E-55 T 23-10-2018 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Gene3D G3DSA:3.40.120.10 252 335 1.5E-55 T 23-10-2018 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0184 a3c890c6fd982d710b53c7d2f4e168d5 454 Gene3D G3DSA:3.30.310.50 365 454 2.3E-23 T 23-10-2018 TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 Gene3D G3DSA:3.30.70.140 1 95 1.1E-35 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 SUPERFAMILY SSF54893 2 96 1.7E-32 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 94 1.5E-31 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 147 34.022 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 95 8.0E-28 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 Gene3D G3DSA:2.30.30.20 96 146 4.6E-23 T 23-10-2018 TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 98 144 9.7E-20 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 1 146 4.7E-59 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TSIB_0444 4bdb46be1736a3a7c04926fc80bd6443 150 SUPERFAMILY SSF57825 98 146 7.72E-17 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 2.6E-25 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 Gene3D G3DSA:3.30.1250.10 8 87 1.6E-30 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 Pfam PF09377 SBDS protein C-terminal domain 101 200 3.4E-18 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 Gene3D G3DSA:1.10.10.900 88 162 2.7E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 4.7E-93 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 SUPERFAMILY SSF109728 82 155 3.14E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 SUPERFAMILY SSF89895 4 87 2.49E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 Gene3D G3DSA:3.30.70.240 163 235 7.6E-29 T 23-10-2018 TSIB_1351 e84f46b9d951e17106b249fbde6cd5ca 236 SUPERFAMILY SSF54980 157 228 1.96E-21 T 23-10-2018 IPR035647 EF-G domain III/V-like TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 Gene3D G3DSA:3.40.50.720 162 296 1.1E-130 T 23-10-2018 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 SMART SM00829 21 350 5.8E-7 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 143 1.5E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 Gene3D G3DSA:3.90.180.10 26 343 1.1E-130 T 23-10-2018 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 SUPERFAMILY SSF51735 151 315 6.54E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 Pfam PF00107 Zinc-binding dehydrogenase 183 312 8.5E-32 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 13 351 1.4E-177 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TSIB_0615 e2d2fbbae40d540e9b8dcbf1215d410e 352 SUPERFAMILY SSF50129 9 182 1.23E-52 T 23-10-2018 IPR011032 GroES-like superfamily TSIB_0544 5b788d7769b6ff9210e9a7a388fe465b 313 Gene3D G3DSA:1.10.150.20 60 103 3.8E-5 T 23-10-2018 TSIB_0544 5b788d7769b6ff9210e9a7a388fe465b 313 Gene3D G3DSA:3.30.420.10 141 263 9.3E-10 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSIB_0544 5b788d7769b6ff9210e9a7a388fe465b 313 Pfam PF13482 RNase_H superfamily 144 307 6.2E-32 T 23-10-2018 IPR038720 YprB, ribonuclease H-like domain TSIB_0544 5b788d7769b6ff9210e9a7a388fe465b 313 SUPERFAMILY SSF53098 94 307 3.8E-27 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TSIB_0620 1f56dea407ab382007fbf899bc24c742 422 SUPERFAMILY SSF143968 283 420 1.03E-40 T 23-10-2018 TSIB_0620 1f56dea407ab382007fbf899bc24c742 422 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 2 410 2.0E-111 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSIB_0620 1f56dea407ab382007fbf899bc24c742 422 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 387 1.7E-95 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSIB_0620 1f56dea407ab382007fbf899bc24c742 422 SUPERFAMILY SSF50475 9 278 5.49E-62 T 23-10-2018 TSIB_0620 1f56dea407ab382007fbf899bc24c742 422 Gene3D G3DSA:3.40.1670.10 297 409 2.1E-37 T 23-10-2018 TSIB_1516 11e3160786ef6f8a10c9bdb4e50bcdb4 215 Pfam PF00881 Nitroreductase family 101 187 8.2E-13 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_1516 11e3160786ef6f8a10c9bdb4e50bcdb4 215 Pfam PF00881 Nitroreductase family 44 97 3.2E-17 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_1516 11e3160786ef6f8a10c9bdb4e50bcdb4 215 Gene3D G3DSA:3.40.109.10 37 210 1.5E-52 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1516 11e3160786ef6f8a10c9bdb4e50bcdb4 215 SUPERFAMILY SSF55469 37 211 9.16E-51 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 Gene3D G3DSA:2.160.10.10 1 152 1.0E-45 T 23-10-2018 TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 36 69 2.5E-10 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 SUPERFAMILY SSF51161 4 157 4.06E-45 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 6 33 4.6E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 2.8E-6 T 23-10-2018 IPR001451 Hexapeptide repeat TSIB_2027 8efe845f00be42efaaaa3ba1c1155a9f 201 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 111 139 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSIB_0772 a187ff542fe7365469d1660927b6807f 384 SUPERFAMILY SSF46548 25 124 2.62E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_0772 a187ff542fe7365469d1660927b6807f 384 Pfam PF13183 4Fe-4S dicluster domain 39 106 3.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0772 a187ff542fe7365469d1660927b6807f 384 Pfam PF02754 Cysteine-rich domain 159 237 1.2E-13 T 23-10-2018 IPR004017 Cysteine-rich domain TSIB_0772 a187ff542fe7365469d1660927b6807f 384 Pfam PF02754 Cysteine-rich domain 277 364 2.1E-11 T 23-10-2018 IPR004017 Cysteine-rich domain TSIB_0772 a187ff542fe7365469d1660927b6807f 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0772 a187ff542fe7365469d1660927b6807f 384 Gene3D G3DSA:1.10.1060.10 29 125 3.9E-6 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_0755 62d6f2f934a4f51c816ad1a57fc8bd53 94 PIRSF PIRSF004604 1 94 5.1E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TSIB_0755 62d6f2f934a4f51c816ad1a57fc8bd53 94 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 93 2.0E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TSIB_0755 62d6f2f934a4f51c816ad1a57fc8bd53 94 Pfam PF08967 Domain of unknown function (DUF1884) 2 93 2.6E-41 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TSIB_0755 62d6f2f934a4f51c816ad1a57fc8bd53 94 Gene3D G3DSA:3.30.2320.10 1 93 4.1E-28 T 23-10-2018 TSIB_0755 62d6f2f934a4f51c816ad1a57fc8bd53 94 SUPERFAMILY SSF111057 1 93 1.96E-31 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Hamap MF_00069 Hydroxylamine reductase [hcp]. 11 440 16.087 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 35 439 1.4E-186 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Gene3D G3DSA:3.40.50.2030 271 439 4.3E-59 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Pfam PF03063 Prismane/CO dehydrogenase family 90 435 2.2E-96 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Pfam PF03063 Prismane/CO dehydrogenase family 11 93 2.6E-16 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Gene3D G3DSA:1.20.1270.20 32 117 1.3E-27 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 SUPERFAMILY SSF56821 9 439 1.5E-145 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 TSIB_1742 af0e8fa86916eb56509ab0359ed98bc6 456 Gene3D G3DSA:3.40.50.2030 123 270 5.9E-54 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TSIB_1352 2958f9a890286fac4009aeed4828152b 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 235 3.1E-109 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TSIB_1352 2958f9a890286fac4009aeed4828152b 260 Pfam PF00227 Proteasome subunit 33 215 1.0E-68 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1352 2958f9a890286fac4009aeed4828152b 260 SUPERFAMILY SSF56235 7 240 6.11E-85 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1352 2958f9a890286fac4009aeed4828152b 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 48.751 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TSIB_1352 2958f9a890286fac4009aeed4828152b 260 Gene3D G3DSA:3.60.20.10 5 253 3.2E-96 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSIB_1352 2958f9a890286fac4009aeed4828152b 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_1352 2958f9a890286fac4009aeed4828152b 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.3E-13 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSIB_0216 eef4ee2e9fb20fdceac53733e3ab6e91 717 Pfam PF04471 Restriction endonuclease 18 123 7.3E-11 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TSIB_0216 eef4ee2e9fb20fdceac53733e3ab6e91 717 Pfam PF03413 Peptidase propeptide and YPEB domain 576 630 0.0063 T 23-10-2018 IPR025711 PepSY domain TSIB_0216 eef4ee2e9fb20fdceac53733e3ab6e91 717 SUPERFAMILY SSF160574 519 596 2.22E-5 T 23-10-2018 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 SUPERFAMILY SSF50465 321 424 4.68E-40 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 3.0E-58 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 3.6E-38 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Gene3D G3DSA:3.40.50.300 1 212 1.3E-85 T 23-10-2018 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Gene3D G3DSA:2.40.30.10 216 310 4.6E-41 T 23-10-2018 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 SUPERFAMILY SSF52540 3 236 5.52E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 426 8.4E-214 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 2.2E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 4.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 4.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 4.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 4.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 SUPERFAMILY SSF50447 213 315 1.25E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.406 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 9.9E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSIB_1561 daf72790ef4ef3e2fd89970c8e0498b8 428 Gene3D G3DSA:2.40.30.10 320 425 1.2E-41 T 23-10-2018 TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 Pfam PF12800 4Fe-4S binding domain 23 37 0.061 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 Pfam PF13247 4Fe-4S dicluster domain 62 140 1.5E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 PRINTS PR00354 7Fe ferredoxin signature 66 76 9.1E-6 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 PRINTS PR00354 7Fe ferredoxin signature 94 111 9.1E-6 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 PRINTS PR00354 7Fe ferredoxin signature 76 86 9.1E-6 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 Gene3D G3DSA:3.30.70.20 39 151 7.6E-21 T 23-10-2018 TSIB_1132 bcf006adb2e29d8637f2844bbabe2ad0 183 SUPERFAMILY SSF54862 15 148 2.09E-37 T 23-10-2018 TSIB_0694 253446291a522f2757d7b63e4e842968 362 Gene3D G3DSA:3.30.460.20 9 171 2.1E-49 T 23-10-2018 TSIB_0694 253446291a522f2757d7b63e4e842968 362 Pfam PF01544 CorA-like Mg2+ transporter protein 69 358 1.4E-78 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSIB_0694 253446291a522f2757d7b63e4e842968 362 SUPERFAMILY SSF144083 297 360 2.62E-24 T 23-10-2018 TSIB_0694 253446291a522f2757d7b63e4e842968 362 SUPERFAMILY SSF143865 18 295 4.58E-85 T 23-10-2018 TSIB_0694 253446291a522f2757d7b63e4e842968 362 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 50 362 5.2E-108 T 23-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 TSIB_0694 253446291a522f2757d7b63e4e842968 362 Gene3D G3DSA:1.20.58.340 172 283 1.5E-42 T 23-10-2018 TSIB_0694 253446291a522f2757d7b63e4e842968 362 Gene3D G3DSA:1.20.58.340 285 362 3.1E-37 T 23-10-2018 TSIB_0279 8e10ce6abfebb8da48da8c27531b9966 159 SUPERFAMILY SSF48452 6 83 9.7E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0279 8e10ce6abfebb8da48da8c27531b9966 159 Gene3D G3DSA:1.25.40.10 2 138 7.1E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1670 686a6350a40943cde0c128f13ce2eaf7 181 Pfam PF00857 Isochorismatase family 3 179 5.4E-45 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSIB_1670 686a6350a40943cde0c128f13ce2eaf7 181 SUPERFAMILY SSF52499 3 181 3.92E-52 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSIB_1670 686a6350a40943cde0c128f13ce2eaf7 181 Gene3D G3DSA:3.40.50.850 1 177 1.9E-68 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSIB_1466 dc062b39dd2201d2c83553f6de9d3132 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.3E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_1466 dc062b39dd2201d2c83553f6de9d3132 186 SUPERFAMILY SSF53323 1 180 7.72E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1466 dc062b39dd2201d2c83553f6de9d3132 186 Gene3D G3DSA:3.40.920.10 1 185 1.2E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_1247 62a2174448b814b6918e7c40b1cde431 343 Pfam PF17231 Family of unknown function (DUF5305) 133 337 3.9E-11 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 TSIB_1167 e4925c9f4d163302521cf44acf092888 337 SUPERFAMILY SSF102114 58 284 9.55E-19 T 23-10-2018 TSIB_1167 e4925c9f4d163302521cf44acf092888 337 Gene3D G3DSA:3.20.20.70 60 277 9.5E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1167 e4925c9f4d163302521cf44acf092888 337 PIRSF PIRSF004869 3 308 4.4E-64 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TSIB_1167 e4925c9f4d163302521cf44acf092888 337 Pfam PF04055 Radical SAM superfamily 80 207 1.9E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 Gene3D G3DSA:3.30.70.360 155 264 1.3E-61 T 23-10-2018 TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 Pfam PF07687 Peptidase dimerisation domain 152 258 3.1E-7 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 SUPERFAMILY SSF55031 133 261 7.33E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 Pfam PF01546 Peptidase family M20/M25/M40 62 343 1.1E-25 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 Gene3D G3DSA:3.40.630.10 14 336 1.3E-61 T 23-10-2018 TSIB_1453 9e607bef022eefa80e64570b4075f9d3 350 SUPERFAMILY SSF53187 8 343 3.14E-43 T 23-10-2018 TSIB_1191 53e47a5e0614d785ff945ea8c86b468b 214 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 107 204 3.0E-35 T 23-10-2018 TSIB_1191 53e47a5e0614d785ff945ea8c86b468b 214 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 1 212 23.259 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 TSIB_1191 53e47a5e0614d785ff945ea8c86b468b 214 Pfam PF01876 RNase P subunit p30 21 201 4.8E-34 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSIB_1191 53e47a5e0614d785ff945ea8c86b468b 214 SUPERFAMILY SSF89550 1 208 9.42E-36 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSIB_1191 53e47a5e0614d785ff945ea8c86b468b 214 Gene3D G3DSA:3.20.20.140 1 210 2.0E-88 T 23-10-2018 TSIB_1531 dab96c5613f33beb5412b92ca7bbc758 162 Gene3D G3DSA:1.20.58.2050 1 162 6.2E-86 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 TSIB_1531 dab96c5613f33beb5412b92ca7bbc758 162 Pfam PF05916 GINS complex protein 25 145 1.6E-5 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 SUPERFAMILY SSF117892 55 188 3.66E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 SMART SM00244 24 181 3.8E-71 T 23-10-2018 IPR001107 Band 7 domain TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 Gene3D G3DSA:3.30.479.30 52 183 8.2E-52 T 23-10-2018 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 31 53 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 113 130 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 176 197 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 133 156 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 157 175 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 78 99 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 PRINTS PR00721 Stomatin signature 201 224 9.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 ProSitePatterns PS01270 Band 7 protein family signature. 137 165 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site TSIB_0677 491cc79ebc018fb6904501a0a5eb063e 268 Pfam PF01145 SPFH domain / Band 7 family 28 198 3.8E-38 T 23-10-2018 IPR001107 Band 7 domain TSIB_1269 5171239fc46dfa14058101d518b3f0dc 476 Gene3D G3DSA:3.10.310.30 337 468 2.2E-11 T 23-10-2018 TSIB_1269 5171239fc46dfa14058101d518b3f0dc 476 SUPERFAMILY SSF64182 7 470 1.05E-65 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TSIB_1269 5171239fc46dfa14058101d518b3f0dc 476 Pfam PF02272 DHHA1 domain 327 463 1.5E-22 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSIB_1269 5171239fc46dfa14058101d518b3f0dc 476 Gene3D G3DSA:3.90.1640.30 3 237 2.0E-24 T 23-10-2018 TSIB_1012 1add75df8cc993893506cbf2edfffa04 110 PIRSF PIRSF016134 1 110 1.2E-43 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TSIB_1012 1add75df8cc993893506cbf2edfffa04 110 Pfam PF04266 ASCH domain 5 107 2.1E-16 T 23-10-2018 IPR007374 ASCH domain TSIB_1012 1add75df8cc993893506cbf2edfffa04 110 Gene3D G3DSA:2.30.130.30 1 108 1.3E-44 T 23-10-2018 TSIB_1012 1add75df8cc993893506cbf2edfffa04 110 SUPERFAMILY SSF88697 1 107 3.64E-36 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1012 1add75df8cc993893506cbf2edfffa04 110 SMART SM01022 5 108 6.5E-16 T 23-10-2018 IPR007374 ASCH domain TSIB_0239 0eef49ff7779be3e2dc6d76a845c67ff 212 Gene3D G3DSA:3.40.50.11570 2 211 9.0E-40 T 23-10-2018 TSIB_0239 0eef49ff7779be3e2dc6d76a845c67ff 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 7 141 2.5E-30 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 24 125 4.0E-45 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 SUPERFAMILY SSF52042 4 126 3.66E-46 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 SMART SM01393 18 125 8.8E-61 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 Pfam PF01655 Ribosomal protein L32 18 125 3.9E-41 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0306 7dfe634bbbf129cfc2d46c59f96e3a44 127 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.226 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 TSIB_0196 d143b720f185fa335b72edb9917b98c3 371 SUPERFAMILY SSF48208 199 362 6.63E-8 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSIB_0196 d143b720f185fa335b72edb9917b98c3 371 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 194 365 1.7E-41 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 TSIB_0359 865aae82e0e9b39aac1034d3aa6b2f59 293 SUPERFAMILY SSF161098 45 284 3.27E-53 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0359 865aae82e0e9b39aac1034d3aa6b2f59 293 Gene3D G3DSA:1.10.3720.10 41 293 5.3E-64 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0359 865aae82e0e9b39aac1034d3aa6b2f59 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 290 9.1E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0359 865aae82e0e9b39aac1034d3aa6b2f59 293 SUPERFAMILY SSF160964 7 36 2.62E-6 T 23-10-2018 TSIB_0638 458a0fb2635150989a82bf968ab66b5b 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_0638 458a0fb2635150989a82bf968ab66b5b 168 SUPERFAMILY SSF54862 40 130 1.45E-14 T 23-10-2018 TSIB_0638 458a0fb2635150989a82bf968ab66b5b 168 Pfam PF00037 4Fe-4S binding domain 67 88 1.3E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_0638 458a0fb2635150989a82bf968ab66b5b 168 Gene3D G3DSA:3.30.70.20 36 106 4.3E-11 T 23-10-2018 TSIB_1786 648b0abb5cf1aba7e671acd8b00522b6 226 Gene3D G3DSA:3.30.420.440 1 226 6.1E-102 T 23-10-2018 TSIB_1786 648b0abb5cf1aba7e671acd8b00522b6 226 Pfam PF13680 Protein of unknown function (DUF4152) 1 223 2.0E-128 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 TSIB_0633 3302e5069c65578f993b8c2b4859b2fc 331 Gene3D G3DSA:3.10.310.10 143 307 2.3E-115 T 23-10-2018 TSIB_0633 3302e5069c65578f993b8c2b4859b2fc 331 Gene3D G3DSA:3.10.310.10 7 330 2.3E-115 T 23-10-2018 TSIB_0633 3302e5069c65578f993b8c2b4859b2fc 331 SUPERFAMILY SSF54506 1 328 7.29E-97 T 23-10-2018 TSIB_0633 3302e5069c65578f993b8c2b4859b2fc 331 Pfam PF05544 Proline racemase 9 328 1.1E-105 T 23-10-2018 IPR008794 Proline racemase family TSIB_0633 3302e5069c65578f993b8c2b4859b2fc 331 PIRSF PIRSF029792 1 331 4.9E-114 T 23-10-2018 IPR008794 Proline racemase family TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 Gene3D G3DSA:1.10.10.1150 36 95 4.3E-6 T 23-10-2018 TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 Gene3D G3DSA:3.20.20.70 128 421 2.4E-44 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 47 92 4.9E-9 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 Pfam PF13186 Iron-sulfur cluster-binding domain 360 427 1.1E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 SMART SM00729 134 335 9.3E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 360 443 1.8E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 Pfam PF04055 Radical SAM superfamily 140 285 4.0E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1984 209f7150dc95ddc9e38b4547a062a089 489 SUPERFAMILY SSF102114 132 437 1.11E-53 T 23-10-2018 TSIB_0520 7b0683a7a1bb32c8e5f9afc3ea85860b 179 SUPERFAMILY SSF49764 48 169 1.05E-33 T 23-10-2018 IPR008978 HSP20-like chaperone TSIB_0520 7b0683a7a1bb32c8e5f9afc3ea85860b 179 Gene3D G3DSA:2.60.40.790 7 173 6.4E-34 T 23-10-2018 IPR008978 HSP20-like chaperone TSIB_0520 7b0683a7a1bb32c8e5f9afc3ea85860b 179 Pfam PF00011 Hsp20/alpha crystallin family 74 171 1.5E-20 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 Gene3D G3DSA:3.30.559.10 43 271 9.2E-83 T 23-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 Pfam PF02817 e3 binding domain 7 35 6.5E-6 T 23-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 48 269 2.6E-79 T 23-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 Gene3D G3DSA:4.10.320.10 2 42 3.7E-9 T 23-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 SUPERFAMILY SSF52777 49 268 1.33E-74 T 23-10-2018 TSIB_1641 adee7ec086f7e795d5609004ba32171d 272 SUPERFAMILY SSF47005 5 39 5.1E-7 T 23-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 Pfam PF08984 Domain of unknown function (DUF1858) 87 144 6.5E-18 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 SUPERFAMILY SSF64307 2 66 1.83E-9 T 23-10-2018 IPR036868 TusA-like domain superfamily TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 Gene3D G3DSA:3.30.110.40 1 66 3.6E-5 T 23-10-2018 IPR036868 TusA-like domain superfamily TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 SUPERFAMILY SSF140683 86 151 9.02E-18 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 Pfam PF01206 Sulfurtransferase TusA 2 66 3.3E-8 T 23-10-2018 IPR001455 TusA-like domain TSIB_1741 8e69875ce41b80257e49c2ecc545acc6 157 Gene3D G3DSA:1.10.3910.10 82 152 7.7E-20 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSIB_2030 c62f280a79c6dece20b2bc01a0a90755 133 Pfam PF01909 Nucleotidyltransferase domain 12 100 3.1E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_2030 c62f280a79c6dece20b2bc01a0a90755 133 Gene3D G3DSA:3.30.460.10 1 100 5.5E-17 T 23-10-2018 TSIB_2030 c62f280a79c6dece20b2bc01a0a90755 133 SUPERFAMILY SSF81301 3 121 3.05E-16 T 23-10-2018 TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 SUPERFAMILY SSF48239 270 501 9.03E-16 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 SUPERFAMILY SSF48239 60 346 1.03E-19 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 292 330 2.4E-5 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 61 91 0.041 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 Gene3D G3DSA:1.50.10.20 17 152 9.0E-14 T 23-10-2018 TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 Gene3D G3DSA:1.50.10.20 199 355 2.1E-7 T 23-10-2018 TSIB_0034 e0cdddd8fb4fd0a1e765e1e2944d234e 740 Gene3D G3DSA:1.50.10.20 366 517 1.7E-11 T 23-10-2018 TSIB_1680 d32814f720070ccdbeb2ca9ffde0c861 341 Gene3D G3DSA:1.10.3490.10 238 327 4.6E-52 T 23-10-2018 TSIB_1680 d32814f720070ccdbeb2ca9ffde0c861 341 ProDom PD038575 MJECL12 PLASMID PH0156 104 326 6.0E-62 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TSIB_1680 d32814f720070ccdbeb2ca9ffde0c861 341 Gene3D G3DSA:3.40.50.10620 103 329 4.6E-52 T 23-10-2018 TSIB_1680 d32814f720070ccdbeb2ca9ffde0c861 341 SUPERFAMILY SSF160945 103 337 6.8E-86 T 23-10-2018 TSIB_1680 d32814f720070ccdbeb2ca9ffde0c861 341 Pfam PF11536 Protein of unknown function (DUF3226) 104 331 4.7E-56 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TSIB_1427 8b800d524af70b71233c3468cf17b3d5 237 Gene3D G3DSA:3.40.50.2020 61 236 1.3E-38 T 23-10-2018 TSIB_1427 8b800d524af70b71233c3468cf17b3d5 237 Pfam PF00156 Phosphoribosyl transferase domain 89 214 1.5E-11 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_1427 8b800d524af70b71233c3468cf17b3d5 237 SUPERFAMILY SSF53271 72 222 2.84E-31 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_1427 8b800d524af70b71233c3468cf17b3d5 237 SUPERFAMILY SSF47413 14 62 2.09E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_1427 8b800d524af70b71233c3468cf17b3d5 237 Pfam PF01381 Helix-turn-helix 14 61 2.2E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSIB_0644 6d17cc9cc9b7de36c77d100ee8236dd7 51 Gene3D G3DSA:1.10.1620.10 2 51 1.0E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TSIB_0644 6d17cc9cc9b7de36c77d100ee8236dd7 51 Pfam PF00832 Ribosomal L39 protein 9 50 2.5E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0644 6d17cc9cc9b7de36c77d100ee8236dd7 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.004 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0644 6d17cc9cc9b7de36c77d100ee8236dd7 51 SUPERFAMILY SSF48662 4 50 1.19E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TSIB_0644 6d17cc9cc9b7de36c77d100ee8236dd7 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 Gene3D G3DSA:1.10.10.10 5 54 6.5E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 2.8E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 Gene3D G3DSA:3.30.70.920 55 150 2.4E-9 T 23-10-2018 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 SUPERFAMILY SSF54909 68 149 5.23E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 SUPERFAMILY SSF46785 4 61 8.85E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 SMART SM00344 4 112 5.8E-23 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1241 9bf503ac7bafa91b3cc72ca1eea03b86 163 Pfam PF01037 Lrp/AsnC ligand binding domain 85 125 8.1E-7 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1663 af2ad2fedf0837218bc1ed92c8914d80 206 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 6 200 2.1E-28 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 TSIB_1663 af2ad2fedf0837218bc1ed92c8914d80 206 Gene3D G3DSA:3.90.320.10 2 202 8.2E-25 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 5.9E-35 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 2.9E-11 T 23-10-2018 TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 SUPERFAMILY SSF54862 32 103 2.88E-25 T 23-10-2018 TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 Gene3D G3DSA:3.30.70.20 69 105 2.1E-9 T 23-10-2018 TSIB_1383 3ba3e496c378e71cdfe5917a6e4166d7 105 Gene3D G3DSA:3.30.70.20 31 68 1.5E-6 T 23-10-2018 TSIB_1357 ec3572c8acb7afcc076f769a10542364 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 1.7E-29 T 23-10-2018 IPR023140 Domain of unknown function DUF357 TSIB_1357 ec3572c8acb7afcc076f769a10542364 95 SUPERFAMILY SSF158372 4 85 9.42E-26 T 23-10-2018 IPR036809 AF1782-like superfamily TSIB_1357 ec3572c8acb7afcc076f769a10542364 95 Gene3D G3DSA:1.20.1270.90 4 86 4.0E-25 T 23-10-2018 TSIB_1608 8d6d57d19c17d63a2402d4f6d9a347a8 206 SUPERFAMILY SSF46785 6 190 1.54E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1608 8d6d57d19c17d63a2402d4f6d9a347a8 206 Gene3D G3DSA:1.10.10.10 6 107 7.9E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1608 8d6d57d19c17d63a2402d4f6d9a347a8 206 SMART SM00418 11 91 2.5E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_1608 8d6d57d19c17d63a2402d4f6d9a347a8 206 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 1.3E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSIB_0418 a4216040de458a24a9d5b652858da87f 951 Gene3D G3DSA:3.40.50.12610 488 715 1.2E-80 T 23-10-2018 TSIB_0418 a4216040de458a24a9d5b652858da87f 951 Gene3D G3DSA:2.40.128.390 595 675 1.2E-80 T 23-10-2018 TSIB_0418 a4216040de458a24a9d5b652858da87f 951 Gene3D G3DSA:2.60.40.3030 811 942 3.4E-87 T 23-10-2018 TSIB_0418 a4216040de458a24a9d5b652858da87f 951 Gene3D G3DSA:2.60.40.3020 717 950 3.4E-87 T 23-10-2018 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 1.2E-86 T 23-10-2018 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 Gene3D G3DSA:3.40.1350.30 112 257 1.0E-118 T 23-10-2018 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 SUPERFAMILY SSF53335 60 413 1.12E-67 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 Gene3D G3DSA:3.40.50.150 73 410 1.0E-118 T 23-10-2018 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 246 409 6.2E-21 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 Gene3D G3DSA:2.40.50.140 1 71 2.9E-14 T 23-10-2018 TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 SUPERFAMILY SSF50249 2 57 2.63E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0448 c787e958d0330decf1f2be81af8c69b0 419 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TSIB_0103 4e86dd75ba8588398a5ce666f4353692 333 SUPERFAMILY SSF53335 84 332 3.0E-43 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0103 4e86dd75ba8588398a5ce666f4353692 333 Gene3D G3DSA:3.30.300.110 61 143 1.3E-13 T 23-10-2018 TSIB_0103 4e86dd75ba8588398a5ce666f4353692 333 Gene3D G3DSA:3.40.50.150 147 332 4.1E-35 T 23-10-2018 TSIB_0103 4e86dd75ba8588398a5ce666f4353692 333 Pfam PF02475 Met-10+ like-protein 86 272 6.4E-38 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TSIB_0786 c5cb790f543379f1c1d59fa92e2c2520 218 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 8 31 9.6E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TSIB_0786 c5cb790f543379f1c1d59fa92e2c2520 218 Pfam PF01917 Archaebacterial flagellin 10 200 2.0E-46 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TSIB_0846 d020bc1fc764ef46f33ddf8df6faa785 509 Pfam PF00361 Proton-conducting membrane transporter 121 384 4.5E-46 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0846 d020bc1fc764ef46f33ddf8df6faa785 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 226 250 2.3E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0846 d020bc1fc764ef46f33ddf8df6faa785 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 359 385 2.3E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0846 d020bc1fc764ef46f33ddf8df6faa785 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 157 181 2.3E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0846 d020bc1fc764ef46f33ddf8df6faa785 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 309 328 2.3E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1790 71480debbe4eec62c7c494576d04579b 214 Pfam PF01813 ATP synthase subunit D 13 206 2.4E-61 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1790 71480debbe4eec62c7c494576d04579b 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.809 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1790 71480debbe4eec62c7c494576d04579b 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 4.1E-71 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 Gene3D G3DSA:3.40.50.300 18 183 4.3E-47 T 23-10-2018 TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 PIRSF PIRSF002849 1 309 2.3E-131 T 23-10-2018 TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 2.0E-62 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 SMART SM00382 34 175 0.0014 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 Gene3D G3DSA:1.10.8.300 197 305 7.4E-35 T 23-10-2018 TSIB_0010 e464aa1187046f3c1bd7703e5d933167 309 SUPERFAMILY SSF52540 5 280 4.5E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0069 81ee3185c5148ec0a6545e3c69582762 222 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 16 55 4.0E-8 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TSIB_0069 81ee3185c5148ec0a6545e3c69582762 222 Pfam PF04256 Protein of unknown function (DUF434) 4 58 3.4E-24 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 420 432 3.5E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 3.5E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 413 3.5E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 363 371 3.5E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 386 3.5E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 Gene3D G3DSA:3.20.20.80 1 466 6.8E-145 T 23-10-2018 TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 SUPERFAMILY SSF51445 10 454 1.62E-120 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TSIB_0334 7df46d1f025bd3048c70a5dc7c62bb1e 467 Pfam PF00232 Glycosyl hydrolase family 1 107 450 1.3E-55 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0836 00b38d19ad639c776679abe2aa47ac0a 149 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 4 74 1.3E-21 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 TSIB_0434 0a6ecfbecc9326397c1d95eb0fa81ae2 169 Pfam PF13184 NusA-like KH domain 57 124 3.8E-9 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TSIB_0434 0a6ecfbecc9326397c1d95eb0fa81ae2 169 Gene3D G3DSA:3.30.300.20 47 97 4.0E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_0434 0a6ecfbecc9326397c1d95eb0fa81ae2 169 SMART SM00322 57 119 4.0E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TSIB_0434 0a6ecfbecc9326397c1d95eb0fa81ae2 169 SUPERFAMILY SSF54814 39 96 5.69E-9 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSIB_0820 e1b189d48bbfc4b9bb5ed39c450fdf04 582 Pfam PF02538 Hydantoinase B/oxoprolinase 7 528 4.2E-159 T 23-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 Pfam PF01048 Phosphorylase superfamily 3 235 3.4E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 44.984 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 237 2.1E-100 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 SUPERFAMILY SSF53167 1 255 3.51E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSIB_1981 106090bd8f1dbd8a4aabf9363ba99dfb 257 Gene3D G3DSA:3.40.50.1580 1 257 9.8E-103 T 23-10-2018 TSIB_1267 393ea3410a6055fdca064966a844ab9c 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.888 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 TSIB_1267 393ea3410a6055fdca064966a844ab9c 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1267 393ea3410a6055fdca064966a844ab9c 200 Pfam PF01015 Ribosomal S3Ae family 11 198 1.9E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1267 393ea3410a6055fdca064966a844ab9c 200 SMART SM01397 8 198 2.2E-104 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0861 8bb7867f98e33045afa9b062786f6210 225 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 225 38.272 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 TSIB_0861 8bb7867f98e33045afa9b062786f6210 225 SUPERFAMILY SSF56281 1 224 2.92E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0861 8bb7867f98e33045afa9b062786f6210 225 Pfam PF13483 Beta-lactamase superfamily domain 3 190 1.4E-36 T 23-10-2018 TSIB_0861 8bb7867f98e33045afa9b062786f6210 225 SMART SM00849 8 190 2.5E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0861 8bb7867f98e33045afa9b062786f6210 225 Gene3D G3DSA:3.60.15.10 2 225 6.2E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 204 242 2.5E-5 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 254 291 1.5E-6 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 304 342 4.4E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 213 242 9.2E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 263 292 0.036 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 SUPERFAMILY SSF50998 181 405 6.91E-17 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 SUPERFAMILY SSF50998 36 250 1.39E-8 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_1417 17c8fe9c29c8a1ba535ea4a8bbe603aa 502 Gene3D G3DSA:2.80.10.50 183 329 1.2E-13 T 23-10-2018 TSIB_0830 a4c16358fc877d68f968ab4d64764ffa 297 Pfam PF00583 Acetyltransferase (GNAT) family 65 154 6.7E-12 T 23-10-2018 IPR000182 GNAT domain TSIB_0830 a4c16358fc877d68f968ab4d64764ffa 297 SUPERFAMILY SSF55729 3 161 1.69E-20 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_0830 a4c16358fc877d68f968ab4d64764ffa 297 Gene3D G3DSA:3.40.630.30 1 173 5.6E-21 T 23-10-2018 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 18 60 1.0E-13 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 SUPERFAMILY SSF63393 3 61 2.62E-22 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 61 28.671 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 SMART SM01389 3 61 6.8E-28 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 Pfam PF06093 Spt4/RpoE2 zinc finger 3 61 2.9E-15 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TSIB_0027 6659f9495ee0674db1003bf4a7b7129a 61 Gene3D G3DSA:2.20.28.90 1 61 2.0E-32 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily TSIB_0926 30d27fa3d6ec50cb4dd145c44655d43b 79 Gene3D G3DSA:3.30.70.920 1 73 4.0E-18 T 23-10-2018 TSIB_0926 30d27fa3d6ec50cb4dd145c44655d43b 79 SUPERFAMILY SSF54909 1 77 6.03E-14 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_0926 30d27fa3d6ec50cb4dd145c44655d43b 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 1.4E-12 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 SUPERFAMILY SSF56228 3 224 5.36E-58 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 220 2.1E-61 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 SUPERFAMILY SSF48310 227 612 3.53E-87 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 SMART SM00790 6 222 1.6E-89 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 Gene3D G3DSA:1.10.599.10 253 610 3.9E-76 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 Gene3D G3DSA:3.60.9.10 3 225 1.0E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 238 610 1.5E-80 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSIB_1133 ff9d3a70d754d9b18e5409a64a0aefe0 626 Gene3D G3DSA:1.10.569.10 254 448 3.9E-76 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 SUPERFAMILY SSF51998 270 782 4.81E-151 T 23-10-2018 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 226 767 2.6E-108 T 23-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 SUPERFAMILY SSF48168 9 155 5.23E-14 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 Pfam PF03477 ATP cone domain 5 93 4.3E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 3.1E-29 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 771 1.3E-226 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 651 3.6E-30 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 PRINTS PR01183 Ribonucleotide reductase large chain signature 531 553 3.6E-30 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 PRINTS PR01183 Ribonucleotide reductase large chain signature 346 365 3.6E-30 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 3.6E-30 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 PRINTS PR01183 Ribonucleotide reductase large chain signature 559 582 3.6E-30 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 121 780 5.1E-228 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 Gene3D G3DSA:3.20.70.20 61 169 6.1E-8 T 23-10-2018 TSIB_1142 08dfebe28745df459b3f89f44dd42115 897 Gene3D G3DSA:3.20.70.20 198 786 1.4E-199 T 23-10-2018 TSIB_0469 6f53eb7194942ba40f5c07c0ae42c238 246 Gene3D G3DSA:3.40.50.620 26 194 1.4E-8 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSIB_0469 6f53eb7194942ba40f5c07c0ae42c238 246 SUPERFAMILY SSF52402 51 189 2.28E-12 T 23-10-2018 TSIB_0469 6f53eb7194942ba40f5c07c0ae42c238 246 PIRSF PIRSF006601 1 246 2.9E-89 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related TSIB_1594 c939c4872e2ff741ceff6f287812057c 175 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 6 157 1.4E-37 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TSIB_1594 c939c4872e2ff741ceff6f287812057c 175 Gene3D G3DSA:3.60.21.10 3 174 3.3E-45 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_1594 c939c4872e2ff741ceff6f287812057c 175 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 157 1.4E-28 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSIB_1594 c939c4872e2ff741ceff6f287812057c 175 SUPERFAMILY SSF56300 4 165 2.11E-37 T 23-10-2018 TSIB_0818 056ef3f5236de99579b93db03087851a 119 Pfam PF07883 Cupin domain 45 103 2.4E-12 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_0818 056ef3f5236de99579b93db03087851a 119 Gene3D G3DSA:2.60.120.10 6 107 7.0E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0818 056ef3f5236de99579b93db03087851a 119 SUPERFAMILY SSF51182 20 110 2.29E-18 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_1650 e3ba35f7df5b24cfe627879ef52192e4 246 Pfam PF07786 Protein of unknown function (DUF1624) 10 228 1.6E-68 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 TSIB_0446 69aa127abe5d5f1455106f8a7a031ac9 189 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 16 181 5.5E-55 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0446 69aa127abe5d5f1455106f8a7a031ac9 189 SUPERFAMILY SSF53271 16 182 7.74E-49 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_0446 69aa127abe5d5f1455106f8a7a031ac9 189 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 189 28.239 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSIB_0446 69aa127abe5d5f1455106f8a7a031ac9 189 Pfam PF00156 Phosphoribosyl transferase domain 45 163 6.5E-24 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_0446 69aa127abe5d5f1455106f8a7a031ac9 189 Gene3D G3DSA:3.40.50.2020 2 189 3.6E-62 T 23-10-2018 TSIB_0853 1e8cb49f1ea66badc24fef6ac533c0f4 267 Pfam PF01040 UbiA prenyltransferase family 22 247 1.5E-34 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSIB_0853 1e8cb49f1ea66badc24fef6ac533c0f4 267 Gene3D G3DSA:1.10.357.140 16 149 8.1E-12 T 23-10-2018 TSIB_1630 0445afbbdc754d36acf01be67598405d 418 Gene3D G3DSA:3.20.20.70 39 352 4.9E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1630 0445afbbdc754d36acf01be67598405d 418 Pfam PF00682 HMGL-like 40 297 1.6E-49 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSIB_1630 0445afbbdc754d36acf01be67598405d 418 SUPERFAMILY SSF51569 34 315 9.38E-66 T 23-10-2018 TSIB_1630 0445afbbdc754d36acf01be67598405d 418 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 226 239 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 SMART SM01211 4 223 2.1E-130 T 23-10-2018 TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 SUPERFAMILY SSF52317 5 223 6.59E-76 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 PIRSF PIRSF001586 3 225 5.3E-85 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 6 222 9.2E-95 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 5 221 44.019 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 Gene3D G3DSA:3.40.50.880 4 225 1.4E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0057 c5a393bd92f5b790df24b88ab6176d18 225 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 5 223 2.0E-50 T 23-10-2018 TSIB_0576 bf1d2daaa800609a72d98998420d5868 59 Gene3D G3DSA:2.20.28.40 1 59 1.9E-30 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TSIB_0576 bf1d2daaa800609a72d98998420d5868 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 20.827 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 TSIB_0576 bf1d2daaa800609a72d98998420d5868 59 SUPERFAMILY SSF144210 4 51 2.62E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TSIB_0576 bf1d2daaa800609a72d98998420d5868 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 2.3E-26 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TSIB_0522 852dca618c8713bccb1b87b61760c2da 170 Gene3D G3DSA:3.40.50.880 3 170 1.8E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0522 852dca618c8713bccb1b87b61760c2da 170 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 170 2.9E-66 T 23-10-2018 IPR006286 Deglycase PfpI TSIB_0522 852dca618c8713bccb1b87b61760c2da 170 SUPERFAMILY SSF52317 5 169 2.29E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0522 852dca618c8713bccb1b87b61760c2da 170 Pfam PF01965 DJ-1/PfpI family 5 167 1.2E-57 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSIB_1134 4047108ac875409d4621f840bbb36a02 158 Gene3D G3DSA:3.30.300.20 11 157 1.2E-35 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TSIB_1134 4047108ac875409d4621f840bbb36a02 158 SUPERFAMILY SSF82784 18 156 6.54E-37 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TSIB_1134 4047108ac875409d4621f840bbb36a02 158 Pfam PF02566 OsmC-like protein 51 154 2.6E-25 T 23-10-2018 IPR003718 OsmC/Ohr family TSIB_0842 648179259f85c80337fa5d165763a1bf 64 Pfam PF13244 Domain of unknown function (DUF4040) 1 63 2.2E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TSIB_1866 fd692332fc42e1e3eac8d8db47deb2cf 362 Pfam PF01988 VIT family 146 351 1.9E-47 T 23-10-2018 IPR008217 Ccc1 family TSIB_1866 fd692332fc42e1e3eac8d8db47deb2cf 362 Gene3D G3DSA:1.20.1260.10 3 140 1.5E-5 T 23-10-2018 IPR012347 Ferritin-like TSIB_1866 fd692332fc42e1e3eac8d8db47deb2cf 362 SUPERFAMILY SSF47240 4 137 9.6E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 Gene3D G3DSA:2.30.130.10 1 68 7.9E-20 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 Pfam PF01472 PUA domain 1 74 2.6E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 Gene3D G3DSA:3.40.50.150 176 393 5.7E-72 T 23-10-2018 TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 Gene3D G3DSA:3.30.750.80 69 175 3.3E-37 T 23-10-2018 TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 SMART SM00359 1 84 3.8E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 SUPERFAMILY SSF53335 76 387 1.59E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 SUPERFAMILY SSF88697 1 66 3.73E-16 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_1771 2ea2bd9a4cc132083f99af68205c3000 393 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 167 331 1.4E-22 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TSIB_1361 a27a8a8d143fab4a46784236f359a876 344 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 313 3.6E-72 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1361 a27a8a8d143fab4a46784236f359a876 344 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 39 57 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TSIB_1361 a27a8a8d143fab4a46784236f359a876 344 Gene3D G3DSA:3.40.50.1100 17 319 7.6E-102 T 23-10-2018 TSIB_1361 a27a8a8d143fab4a46784236f359a876 344 Gene3D G3DSA:3.40.50.1100 51 154 7.6E-102 T 23-10-2018 TSIB_1361 a27a8a8d143fab4a46784236f359a876 344 SUPERFAMILY SSF53686 10 326 1.83E-89 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_1852 5234465e6ddcae9c05f971c3d1f96010 161 PIRSF PIRSF006707 1 161 5.9E-41 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type TSIB_1852 5234465e6ddcae9c05f971c3d1f96010 161 Gene3D G3DSA:1.10.10.10 3 89 1.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1852 5234465e6ddcae9c05f971c3d1f96010 161 SUPERFAMILY SSF46785 7 142 3.04E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1852 5234465e6ddcae9c05f971c3d1f96010 161 Pfam PF01047 MarR family 41 83 4.5E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1398 5934ae3977aeadc160055719a6a5f07d 120 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 100 3.3E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSIB_1398 5934ae3977aeadc160055719a6a5f07d 120 Gene3D G3DSA:2.20.25.200 64 119 1.7E-26 T 23-10-2018 TSIB_1398 5934ae3977aeadc160055719a6a5f07d 120 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 109 26.083 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TSIB_1398 5934ae3977aeadc160055719a6a5f07d 120 Gene3D G3DSA:1.20.5.420 5 63 3.2E-23 T 23-10-2018 TSIB_1398 5934ae3977aeadc160055719a6a5f07d 120 PIRSF PIRSF004878 1 116 9.0E-44 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 Pfam PF00742 Homoserine dehydrogenase 156 327 6.6E-52 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 SUPERFAMILY SSF51735 1 177 1.88E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 SUPERFAMILY SSF55347 156 314 7.85E-41 T 23-10-2018 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 Gene3D G3DSA:3.40.50.720 7 327 7.0E-94 T 23-10-2018 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 1.9E-8 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 PIRSF PIRSF036497 1 335 3.8E-86 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSIB_1477 9fba26803a844c7034aacd9ca0a7e4a0 337 Gene3D G3DSA:3.30.360.10 167 310 7.0E-94 T 23-10-2018 TSIB_1643 ebadf17fec1a1bcec7d102a858a368cd 329 PIRSF PIRSF018567 3 329 3.5E-97 T 23-10-2018 IPR011391 Acetoin catabolism kinase AcoX TSIB_1643 ebadf17fec1a1bcec7d102a858a368cd 329 Pfam PF01513 ATP-NAD kinase 8 174 4.1E-12 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSIB_1643 ebadf17fec1a1bcec7d102a858a368cd 329 Gene3D G3DSA:3.40.50.10330 64 170 1.5E-5 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSIB_1643 ebadf17fec1a1bcec7d102a858a368cd 329 SUPERFAMILY SSF111331 74 312 4.32E-9 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSIB_0001 8f1b8925b601afcb9f670ca29a591095 377 Pfam PF04007 Protein of unknown function (DUF354) 10 285 5.7E-8 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TSIB_0001 8f1b8925b601afcb9f670ca29a591095 377 SUPERFAMILY SSF53756 6 290 6.28E-16 T 23-10-2018 TSIB_0001 8f1b8925b601afcb9f670ca29a591095 377 PIRSF PIRSF005357 6 360 3.8E-61 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TSIB_0001 8f1b8925b601afcb9f670ca29a591095 377 Gene3D G3DSA:3.40.50.2000 2 166 1.8E-5 T 23-10-2018 TSIB_0769 c72f4fcee0613603205498e6b2ada11d 121 Gene3D G3DSA:3.10.530.10 47 116 1.4E-26 T 23-10-2018 IPR036593 CPE0013-like superfamily TSIB_0769 c72f4fcee0613603205498e6b2ada11d 121 Pfam PF07892 Protein of unknown function (DUF1667) 37 115 1.2E-31 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 TSIB_0769 c72f4fcee0613603205498e6b2ada11d 121 SUPERFAMILY SSF160148 47 119 8.89E-26 T 23-10-2018 IPR036593 CPE0013-like superfamily TSIB_0024 8d8584fdadb48be34e10e2f21e284cd9 54 Gene3D G3DSA:3.30.460.10 1 53 1.9E-8 T 23-10-2018 TSIB_0024 8d8584fdadb48be34e10e2f21e284cd9 54 SUPERFAMILY SSF81301 1 54 4.06E-6 T 23-10-2018 TSIB_0540 9f48faa5f2c34a021d6d1ff804ba964b 612 SUPERFAMILY SSF52317 381 611 6.41E-26 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0540 9f48faa5f2c34a021d6d1ff804ba964b 612 Gene3D G3DSA:3.40.50.880 374 607 2.6E-10 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0540 9f48faa5f2c34a021d6d1ff804ba964b 612 Gene3D G3DSA:2.60.40.10 147 243 1.4E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 309 2.8E-18 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 SMART SM00382 45 241 2.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 2.6E-26 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 SUPERFAMILY SSF52540 5 263 9.18E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 Gene3D G3DSA:3.40.50.300 3 335 3.3E-95 T 23-10-2018 TSIB_1757 303f9bbf8017719f60cd654b6b0f2cc1 335 Pfam PF00005 ABC transporter 37 191 3.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0244 1cdac96f39a18eab279dda1e44b48050 220 Gene3D G3DSA:3.40.1280.10 1 218 8.3E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSIB_0244 1cdac96f39a18eab279dda1e44b48050 220 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 39.554 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 TSIB_0244 1cdac96f39a18eab279dda1e44b48050 220 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 1.3E-49 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSIB_0244 1cdac96f39a18eab279dda1e44b48050 220 SUPERFAMILY SSF75217 2 216 3.01E-60 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TSIB_0003 9b0b065d4b3b4db4c9a9061c885b4d4a 180 SUPERFAMILY SSF53756 8 171 1.78E-23 T 23-10-2018 TSIB_0003 9b0b065d4b3b4db4c9a9061c885b4d4a 180 Gene3D G3DSA:3.40.50.2000 1 157 4.3E-24 T 23-10-2018 TSIB_0003 9b0b065d4b3b4db4c9a9061c885b4d4a 180 Pfam PF00534 Glycosyl transferases group 1 3 151 7.7E-16 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_0894 5a9a799b6b250b8c943a9101af75feec 378 Gene3D G3DSA:3.40.640.10 58 275 1.4E-113 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0894 5a9a799b6b250b8c943a9101af75feec 378 SUPERFAMILY SSF53383 44 374 1.17E-78 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0894 5a9a799b6b250b8c943a9101af75feec 378 Gene3D G3DSA:3.90.1150.10 18 365 1.4E-113 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0894 5a9a799b6b250b8c943a9101af75feec 378 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 222 235 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSIB_0894 5a9a799b6b250b8c943a9101af75feec 378 Pfam PF00155 Aminotransferase class I and II 58 354 8.3E-42 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 1.2E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 1.2E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 SUPERFAMILY SSF46785 3 62 8.06E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 Gene3D G3DSA:1.10.10.10 1 55 1.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 Pfam PF08394 Archaeal TRASH domain 144 179 3.5E-19 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 7.6E-17 T 23-10-2018 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 SMART SM00746 144 180 1.2E-8 T 23-10-2018 IPR011017 TRASH domain TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 SMART SM00344 4 111 5.6E-21 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 9.5E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 9.5E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1705 c88ae1bd14c143a7c7d7e9734b4c7f0f 200 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 9.5E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PIRSF PIRSF006615 6 501 4.3E-201 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 SUPERFAMILY SSF55486 9 500 5.13E-115 T 23-10-2018 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 Gene3D G3DSA:1.10.1370.30 2 500 1.2E-198 T 23-10-2018 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 499 4.5E-111 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 233 249 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 270 289 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 151 171 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 297 313 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_1011 06272bc628a6004e4ef41d7a00e36b89 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 250 269 9.5E-83 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSIB_0907 a0a4fb8517b2f8628a44300b3e9a4653 187 SUPERFAMILY SSF53639 8 182 2.16E-51 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0907 a0a4fb8517b2f8628a44300b3e9a4653 187 Gene3D G3DSA:3.40.225.10 2 187 8.5E-55 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0907 a0a4fb8517b2f8628a44300b3e9a4653 187 SMART SM01007 7 181 6.7E-48 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSIB_0907 a0a4fb8517b2f8628a44300b3e9a4653 187 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 180 3.7E-43 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSIB_0077 9bbf565ca920be51291b61e5656c0271 115 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 7.5E-22 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSIB_0077 9bbf565ca920be51291b61e5656c0271 115 SUPERFAMILY SSF46785 10 105 5.66E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0077 9bbf565ca920be51291b61e5656c0271 115 Gene3D G3DSA:1.10.10.10 3 115 3.4E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1299 e60ce9946c1086003d85487105bf4813 174 SUPERFAMILY SSF143243 6 153 3.27E-28 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1299 e60ce9946c1086003d85487105bf4813 174 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 93 150 5.0E-15 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1299 e60ce9946c1086003d85487105bf4813 174 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 151 1.9E-20 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1299 e60ce9946c1086003d85487105bf4813 174 Gene3D G3DSA:3.30.460.80 2 133 2.5E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_0845 69743a4dd5e8ac5971cd487d8fa9b979 97 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 95 3.4E-18 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 Gene3D G3DSA:3.40.50.150 1 194 4.1E-66 T 23-10-2018 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 SMART SM00650 30 193 2.8E-83 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.62 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 263 2.7E-80 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 Gene3D G3DSA:1.10.8.100 195 271 7.3E-10 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 SUPERFAMILY SSF53335 12 268 1.63E-66 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0602 ad718b8a3dab1fdb114811d9b063eb29 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 226 6.3E-57 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 Pfam PF13394 4Fe-4S single cluster domain 27 130 4.4E-9 T 23-10-2018 TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 PIRSF PIRSF000370 1 251 9.7E-33 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 Pfam PF04055 Radical SAM superfamily 29 200 5.9E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 SUPERFAMILY SSF102114 31 208 1.96E-13 T 23-10-2018 TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 251 37.649 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TSIB_0867 f13b9758501099b25bd0c3aba8040a8f 251 Gene3D G3DSA:3.20.20.70 2 251 1.5E-29 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0831 f860341ad1ac312d6b3ae154f46ed7ca 195 Gene3D G3DSA:3.90.550.10 4 194 4.8E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0831 f860341ad1ac312d6b3ae154f46ed7ca 195 SUPERFAMILY SSF53448 1 186 7.3E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0831 f860341ad1ac312d6b3ae154f46ed7ca 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 189 19.85 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TSIB_0831 f860341ad1ac312d6b3ae154f46ed7ca 195 Pfam PF12804 MobA-like NTP transferase domain 3 143 1.7E-31 T 23-10-2018 IPR025877 MobA-like NTP transferase TSIB_1919 f7fca475a2daef2016c9f6871e7cd051 419 Pfam PF04055 Radical SAM superfamily 123 287 1.3E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1919 f7fca475a2daef2016c9f6871e7cd051 419 SUPERFAMILY SSF102114 108 334 3.27E-37 T 23-10-2018 TSIB_1919 f7fca475a2daef2016c9f6871e7cd051 419 Gene3D G3DSA:3.20.20.70 111 374 8.0E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1919 f7fca475a2daef2016c9f6871e7cd051 419 SMART SM00729 115 330 1.0E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 6 86 1.9E-26 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 97 177 4.2E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 141 157 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 32 51 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 51 69 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 8 23 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 99 115 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 PRINTS PR00686 Transcription initiation factor TFIID signature 122 137 9.6E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 SUPERFAMILY SSF55945 94 179 6.91E-30 T 23-10-2018 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 Gene3D G3DSA:3.30.310.10 13 96 4.2E-30 T 23-10-2018 IPR012295 TBP domain superfamily TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 SUPERFAMILY SSF55945 3 91 4.24E-28 T 23-10-2018 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 Gene3D G3DSA:3.30.310.10 97 179 8.0E-35 T 23-10-2018 IPR012295 TBP domain superfamily TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 181 36.784 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0138 67f910ec860e4d09ced0be12f9715580 185 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 126 175 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site TSIB_0188 48a5b0979e968dd943af34369ecacf67 201 Pfam PF13238 AAA domain 11 146 7.0E-19 T 23-10-2018 TSIB_0188 48a5b0979e968dd943af34369ecacf67 201 Gene3D G3DSA:3.40.50.300 9 196 6.2E-40 T 23-10-2018 TSIB_0188 48a5b0979e968dd943af34369ecacf67 201 SUPERFAMILY SSF52540 9 196 5.66E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0791 83ce13e7832d346724ccd1b11ab6d567 227 Gene3D G3DSA:3.40.50.11570 7 219 5.2E-62 T 23-10-2018 TSIB_0791 83ce13e7832d346724ccd1b11ab6d567 227 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 13 214 4.4E-69 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_1510 8f84b635d0d3c399f030fad2e44e3b1b 520 SUPERFAMILY SSF49452 242 301 9.02E-5 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 SUPERFAMILY SSF53187 8 418 4.02E-62 T 23-10-2018 TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 SUPERFAMILY SSF55031 210 321 2.54E-17 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 413 9.8E-81 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 Pfam PF07687 Peptidase dimerisation domain 204 316 5.5E-20 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 Pfam PF01546 Peptidase family M20/M25/M40 95 418 1.7E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 Gene3D G3DSA:3.40.630.10 21 408 5.1E-78 T 23-10-2018 TSIB_1773 0c7f687e200fd8cf960882c228396d46 420 Gene3D G3DSA:3.30.70.360 208 340 5.1E-78 T 23-10-2018 TSIB_1779 f4789ba1ded410f131e08d967ff93089 341 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 339 1.1E-46 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TSIB_1779 f4789ba1ded410f131e08d967ff93089 341 Gene3D G3DSA:1.10.10.10 2 101 1.3E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1779 f4789ba1ded410f131e08d967ff93089 341 SUPERFAMILY SSF46785 4 90 3.64E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1779 f4789ba1ded410f131e08d967ff93089 341 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 6.1E-24 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_1779 f4789ba1ded410f131e08d967ff93089 341 SUPERFAMILY SSF159071 255 340 4.32E-18 T 23-10-2018 TSIB_0399 ee82c91acb21ffe0054fd072bd2d7ddf 434 Hamap MF_02096 DNA repair protein. 27 430 39.411 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 TSIB_0399 ee82c91acb21ffe0054fd072bd2d7ddf 434 Pfam PF04894 Archaeal Nre, N-terminal 44 309 1.1E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal TSIB_0399 ee82c91acb21ffe0054fd072bd2d7ddf 434 Pfam PF04895 Archaeal Nre, C-terminal 321 430 2.1E-37 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal TSIB_0903 74e1df12769c92966c669b1a0c473e99 177 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 4 144 1.1E-28 T 23-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSIB_0903 74e1df12769c92966c669b1a0c473e99 177 Gene3D G3DSA:3.40.190.170 1 173 5.4E-39 T 23-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSIB_1675 60d2020f4300bc7c7294a73431dbf00f 393 SUPERFAMILY SSF103473 7 392 1.7E-57 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1675 60d2020f4300bc7c7294a73431dbf00f 393 Gene3D G3DSA:1.20.1250.20 12 207 4.4E-26 T 23-10-2018 TSIB_1675 60d2020f4300bc7c7294a73431dbf00f 393 Gene3D G3DSA:1.20.1250.20 209 393 1.3E-20 T 23-10-2018 TSIB_1675 60d2020f4300bc7c7294a73431dbf00f 393 Pfam PF07690 Major Facilitator Superfamily 19 351 7.4E-42 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_1388 c0dcaee87e9962f65041ffdffde8d88b 249 SUPERFAMILY SSF52540 5 226 3.55E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1388 c0dcaee87e9962f65041ffdffde8d88b 249 SMART SM00382 28 220 2.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1388 c0dcaee87e9962f65041ffdffde8d88b 249 Pfam PF00005 ABC transporter 19 162 1.2E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1388 c0dcaee87e9962f65041ffdffde8d88b 249 Gene3D G3DSA:3.40.50.300 2 245 5.1E-67 T 23-10-2018 TSIB_2025 9e8ea0afe8b88ca3dc2804c74352bf97 355 Gene3D G3DSA:3.40.50.2000 183 332 2.0E-11 T 23-10-2018 TSIB_2025 9e8ea0afe8b88ca3dc2804c74352bf97 355 Pfam PF13439 Glycosyltransferase Family 4 17 174 1.6E-17 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSIB_2025 9e8ea0afe8b88ca3dc2804c74352bf97 355 Gene3D G3DSA:3.40.50.2000 15 182 3.9E-23 T 23-10-2018 TSIB_2025 9e8ea0afe8b88ca3dc2804c74352bf97 355 SUPERFAMILY SSF53756 18 354 8.03E-38 T 23-10-2018 TSIB_0902 f59f09a37d3d71d1f8ac750b5eac24bc 198 Gene3D G3DSA:3.40.190.170 54 198 8.2E-32 T 23-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSIB_0902 f59f09a37d3d71d1f8ac750b5eac24bc 198 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 65 196 2.2E-11 T 23-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 SUPERFAMILY SSF50249 255 348 7.54E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Pfam PF08489 Domain of unknown function (DUF1743) 141 254 2.3E-39 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Gene3D G3DSA:2.40.50.1010 253 402 4.5E-41 T 23-10-2018 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 4 423 37.28 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Gene3D G3DSA:3.90.600.20 157 252 1.9E-34 T 23-10-2018 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Gene3D G3DSA:3.30.70.2200 3 156 2.7E-59 T 23-10-2018 TSIB_1197 2b7e1ec4562a689d85682fe94b290b85 429 Pfam PF01336 OB-fold nucleic acid binding domain 271 343 1.3E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_1701 d6fbbd3d31567f1f6deb036ab60c97eb 207 Gene3D G3DSA:3.40.109.10 10 206 3.2E-73 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1701 d6fbbd3d31567f1f6deb036ab60c97eb 207 SUPERFAMILY SSF55469 25 206 1.81E-36 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1701 d6fbbd3d31567f1f6deb036ab60c97eb 207 Pfam PF00881 Nitroreductase family 34 203 2.9E-33 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_1701 d6fbbd3d31567f1f6deb036ab60c97eb 207 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 46 203 4.5E-48 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain TSIB_1768 d5ea414c7a41e17a1983f3a700685bb4 252 Gene3D G3DSA:3.40.50.300 9 252 1.6E-72 T 23-10-2018 TSIB_1768 d5ea414c7a41e17a1983f3a700685bb4 252 Pfam PF06745 KaiC 13 249 2.0E-79 T 23-10-2018 IPR014774 KaiC-like domain TSIB_1768 d5ea414c7a41e17a1983f3a700685bb4 252 SUPERFAMILY SSF52540 11 247 9.71E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.0E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.0E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.0E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 Gene3D G3DSA:3.30.70.920 57 149 2.1E-45 T 23-10-2018 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 SMART SM00344 5 111 4.1E-17 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 4.0E-13 T 23-10-2018 TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 SUPERFAMILY SSF46785 4 65 3.82E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1265 b18119c57d95444eb6f6f1a5098971b2 149 Gene3D G3DSA:1.10.10.10 1 56 2.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1091 b61c8547d857ee2ae9c9a8b0e5f36a16 375 Pfam PF01478 Type IV leader peptidase family 8 126 3.2E-6 T 23-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TSIB_1091 b61c8547d857ee2ae9c9a8b0e5f36a16 375 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 233 341 3.6E-26 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea TSIB_1091 b61c8547d857ee2ae9c9a8b0e5f36a16 375 Gene3D G3DSA:1.20.120.1220 2 148 1.8E-18 T 23-10-2018 TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 SUPERFAMILY SSF51735 7 254 4.86E-82 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.2E-13 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.2E-13 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.2E-13 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 Gene3D G3DSA:3.40.50.720 2 259 3.4E-83 T 23-10-2018 TSIB_0318 88d6db83f5c82150866bea7f99ebc335 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 7.8E-69 T 23-10-2018 TSIB_0198 69613070cdc62d329a380f884b80aa9b 298 SUPERFAMILY SSF53639 127 294 1.1E-49 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0198 69613070cdc62d329a380f884b80aa9b 298 SUPERFAMILY SSF47413 25 54 2.29E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_0198 69613070cdc62d329a380f884b80aa9b 298 Pfam PF10120 Thiamine-phosphate synthase 134 292 4.4E-50 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSIB_0198 69613070cdc62d329a380f884b80aa9b 298 Gene3D G3DSA:3.40.225.10 124 298 7.6E-51 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSIB_0198 69613070cdc62d329a380f884b80aa9b 298 Gene3D G3DSA:1.10.260.40 14 59 8.1E-8 T 23-10-2018 TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 Pfam PF13732 Domain of unknown function (DUF4162) 217 302 2.3E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 SMART SM00382 28 212 1.0E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 304 1.8E-121 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 Pfam PF00005 ABC transporter 20 162 2.9E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 SUPERFAMILY SSF52540 3 224 1.98E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0213 61c70a44be0d742abb533f1944e3952e 326 Gene3D G3DSA:3.40.50.300 1 235 3.2E-74 T 23-10-2018 TSIB_1458 008524e445e6301873f53b2bebc35df3 171 Pfam PF03266 NTPase 2 161 9.4E-57 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TSIB_1458 008524e445e6301873f53b2bebc35df3 171 Gene3D G3DSA:3.40.50.300 1 169 8.6E-47 T 23-10-2018 TSIB_1458 008524e445e6301873f53b2bebc35df3 171 SUPERFAMILY SSF52540 3 163 1.55E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1458 008524e445e6301873f53b2bebc35df3 171 Hamap MF_00796 Nucleoside-triphosphatase . 1 169 29.639 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TSIB_1458 008524e445e6301873f53b2bebc35df3 171 SMART SM00382 2 152 0.0077 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 Gene3D G3DSA:1.10.10.10 18 71 4.5E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 SUPERFAMILY SSF46785 21 71 2.31E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 Pfam PF13404 AsnC-type helix-turn-helix domain 22 62 2.0E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 SMART SM00344 22 131 4.9E-5 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 1.4E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 1.4E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_0824 02ca2fae5d70f5fb8d96bcc199de440b 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 38 1.4E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSIB_1938 99f1e4c6796e1d4c596c299fb808e810 66 Pfam PF10130 PIN domain 1 53 8.5E-8 T 23-10-2018 IPR002716 PIN domain TSIB_1774 d1ecbf5d21e7e1286288dbf0f327cfa5 631 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 13 596 7.8E-119 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TSIB_1774 d1ecbf5d21e7e1286288dbf0f327cfa5 631 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 18 596 1.0E-248 T 23-10-2018 IPR004814 Oligopeptide transporter OPT TSIB_1774 d1ecbf5d21e7e1286288dbf0f327cfa5 631 Pfam PF03169 OPT oligopeptide transporter protein 18 594 2.3E-101 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TSIB_0541 e03cf10817fde211605bc23cff4fbdb7 171 SUPERFAMILY SSF89028 1 165 1.22E-48 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSIB_0541 e03cf10817fde211605bc23cff4fbdb7 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 166 1.3E-56 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSIB_0541 e03cf10817fde211605bc23cff4fbdb7 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 19 165 2.0E-48 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSIB_0541 e03cf10817fde211605bc23cff4fbdb7 171 Pfam PF01923 Cobalamin adenosyltransferase 3 160 4.9E-50 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSIB_0541 e03cf10817fde211605bc23cff4fbdb7 171 Gene3D G3DSA:1.20.1200.10 25 171 6.5E-51 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSIB_1674 f41cd2e5fb2b703103386711264d7735 101 SUPERFAMILY SSF46785 3 96 2.19E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1674 f41cd2e5fb2b703103386711264d7735 101 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 1.6E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSIB_1674 f41cd2e5fb2b703103386711264d7735 101 Gene3D G3DSA:1.10.10.10 1 99 4.4E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1547 28a1b88b2fd542b6b21c0183886d32e4 116 Pfam PF01906 Putative heavy-metal-binding 12 112 1.3E-36 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TSIB_1547 28a1b88b2fd542b6b21c0183886d32e4 116 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 11 113 25.462 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TSIB_1547 28a1b88b2fd542b6b21c0183886d32e4 116 Gene3D G3DSA:3.30.110.70 11 116 6.4E-33 T 23-10-2018 TSIB_1547 28a1b88b2fd542b6b21c0183886d32e4 116 SUPERFAMILY SSF117782 11 115 1.83E-36 T 23-10-2018 IPR035439 UPF0145 domain superfamily TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 1.9E-17 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 Gene3D G3DSA:3.40.50.720 2 349 1.2E-132 T 23-10-2018 TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 SUPERFAMILY SSF51735 1 168 1.37E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 347 3.3E-30 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 Gene3D G3DSA:3.30.360.10 118 299 1.2E-132 T 23-10-2018 TSIB_0243 0206e543a4c2f4b8d0b48a9e7a635c67 364 SUPERFAMILY SSF55347 118 252 3.07E-39 T 23-10-2018 TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.4E-9 T 23-10-2018 TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 4.4E-9 T 23-10-2018 TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 Pfam PF01134 Glucose inhibited division protein A 381 456 2.5E-4 T 23-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 Pfam PF01946 Thi4 family 7 38 3.1E-7 T 23-10-2018 TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 SUPERFAMILY SSF51905 5 457 3.89E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 PIRSF PIRSF038984 2 92 1.2E-8 T 23-10-2018 IPR028348 FAD dependent protein TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 PIRSF PIRSF038984 131 463 5.2E-26 T 23-10-2018 IPR028348 FAD dependent protein TSIB_0453 b661a41d321bc1b1662c8ac30ce0c78a 484 Gene3D G3DSA:3.50.50.60 3 116 5.3E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_0095 c12adf0a6532a7be79916ca41f6e615d 442 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 3 423 22.238 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 TSIB_0095 c12adf0a6532a7be79916ca41f6e615d 442 Gene3D G3DSA:3.60.21.10 3 280 5.9E-96 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0095 c12adf0a6532a7be79916ca41f6e615d 442 Pfam PF00149 Calcineurin-like phosphoesterase 3 212 4.3E-16 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_0095 c12adf0a6532a7be79916ca41f6e615d 442 Gene3D G3DSA:3.30.110.80 237 334 5.9E-96 T 23-10-2018 TSIB_0095 c12adf0a6532a7be79916ca41f6e615d 442 SUPERFAMILY SSF56300 3 318 1.16E-52 T 23-10-2018 TSIB_0097 886a7e7f6599d409f29f1b462473b170 403 SMART SM00933 38 368 9.5E-16 T 23-10-2018 IPR018977 NurA domain TSIB_0097 886a7e7f6599d409f29f1b462473b170 403 PIRSF PIRSF018871 181 403 8.6E-38 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TSIB_0097 886a7e7f6599d409f29f1b462473b170 403 PIRSF PIRSF018871 1 204 1.7E-38 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TSIB_0097 886a7e7f6599d409f29f1b462473b170 403 Pfam PF09376 NurA domain 39 368 2.9E-34 T 23-10-2018 IPR018977 NurA domain TSIB_0904 edbe77f90e59ca88043f74cd4fd3b5e1 145 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 7 140 1.4E-21 T 23-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSIB_2053 7c423b5ca1cb874171f150327793989f 308 Gene3D G3DSA:2.115.10.20 1 145 5.0E-10 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSIB_2053 7c423b5ca1cb874171f150327793989f 308 Gene3D G3DSA:2.115.10.20 146 308 2.6E-27 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSIB_2053 7c423b5ca1cb874171f150327793989f 308 SUPERFAMILY SSF75005 71 306 9.1E-31 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSIB_2053 7c423b5ca1cb874171f150327793989f 308 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 180 232 4.4E-7 T 23-10-2018 IPR007184 Mannoside phosphorylase TSIB_0030 2e8cbbd8e036c1075895134e1a89b8ff 55 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 9 54 19.492 T 23-10-2018 IPR022845 Ribosomal protein S27ae TSIB_0030 2e8cbbd8e036c1075895134e1a89b8ff 55 SUPERFAMILY SSF57829 9 55 2.75E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSIB_0030 2e8cbbd8e036c1075895134e1a89b8ff 55 Pfam PF01599 Ribosomal protein S27a 10 51 1.3E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TSIB_0030 2e8cbbd8e036c1075895134e1a89b8ff 55 SMART SM01402 9 51 7.0E-25 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TSIB_0030 2e8cbbd8e036c1075895134e1a89b8ff 55 Gene3D G3DSA:2.20.25.660 1 54 3.3E-20 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TSIB_1433 a2b5ab0995ec90bc6ffae0f9db512824 412 Pfam PF00155 Aminotransferase class I and II 46 386 8.3E-56 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1433 a2b5ab0995ec90bc6ffae0f9db512824 412 SUPERFAMILY SSF53383 19 409 1.75E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1433 a2b5ab0995ec90bc6ffae0f9db512824 412 Gene3D G3DSA:3.40.640.10 68 309 2.1E-143 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1433 a2b5ab0995ec90bc6ffae0f9db512824 412 Gene3D G3DSA:3.90.1150.10 40 405 2.1E-143 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0018 33b1d4dbe4daa39b1096943b8cd48049 328 Pfam PF07760 Protein of unknown function (DUF1616) 11 291 6.8E-96 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 TSIB_0018 33b1d4dbe4daa39b1096943b8cd48049 328 PIRSF PIRSF018671 2 328 2.8E-122 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 Pfam PF02926 THUMP domain 58 164 8.5E-13 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 Gene3D G3DSA:3.30.70.3190 279 387 6.3E-30 T 23-10-2018 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 388 49.13 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 Gene3D G3DSA:3.30.70.2510 166 278 5.8E-31 T 23-10-2018 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 388 5.9E-138 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TSIB_0606 e54cb1cb26e2506f615d2bc4535d3d56 390 SUPERFAMILY SSF55120 274 386 1.58E-12 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSIB_0007 9081a94761d67656e7197ebe25a6648e 765 Gene3D G3DSA:3.40.50.12610 468 594 1.0E-15 T 23-10-2018 TSIB_0007 9081a94761d67656e7197ebe25a6648e 765 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 32 507 1.0E-14 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 TSIB_1298 46c272f2ccd55efff0958a06668d59b1 430 Pfam PF00374 Nickel-dependent hydrogenase 47 114 1.6E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSIB_1298 46c272f2ccd55efff0958a06668d59b1 430 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 380 2.8E-58 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1298 46c272f2ccd55efff0958a06668d59b1 430 Gene3D G3DSA:1.10.645.20 9 380 1.6E-120 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1298 46c272f2ccd55efff0958a06668d59b1 430 SUPERFAMILY SSF56762 18 380 2.22E-102 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1298 46c272f2ccd55efff0958a06668d59b1 430 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 47 72 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSIB_1740 61ebb3404464e47b178470c012d17009 414 SUPERFAMILY SSF52218 268 410 3.91E-27 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1740 61ebb3404464e47b178470c012d17009 414 Gene3D G3DSA:3.40.50.360 266 414 5.1E-28 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1740 61ebb3404464e47b178470c012d17009 414 SUPERFAMILY SSF56281 26 290 1.31E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1740 61ebb3404464e47b178470c012d17009 414 PIRSF PIRSF005243 21 414 6.7E-137 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TSIB_1740 61ebb3404464e47b178470c012d17009 414 Gene3D G3DSA:3.60.15.10 23 264 4.6E-93 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1740 61ebb3404464e47b178470c012d17009 414 SMART SM00849 57 245 4.6E-31 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1740 61ebb3404464e47b178470c012d17009 414 Pfam PF00753 Metallo-beta-lactamase superfamily 57 192 1.6E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 Pfam PF01066 CDP-alcohol phosphatidyltransferase 257 317 2.5E-8 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 Pfam PF12804 MobA-like NTP transferase domain 3 107 5.5E-15 T 23-10-2018 IPR025877 MobA-like NTP transferase TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 Gene3D G3DSA:3.90.550.10 1 220 6.4E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 SUPERFAMILY SSF53448 1 222 2.29E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1010 548545b7b0579d7318d6bbbc1199f7e7 425 Gene3D G3DSA:1.20.120.1760 230 421 3.5E-57 T 23-10-2018 TSIB_0812 1987b50af87759744d7a11e948286164 561 SUPERFAMILY SSF51703 5 555 2.62E-232 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSIB_0812 1987b50af87759744d7a11e948286164 561 Pfam PF01642 Methylmalonyl-CoA mutase 39 553 2.2E-243 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSIB_0812 1987b50af87759744d7a11e948286164 561 Gene3D G3DSA:3.20.20.240 1 561 7.0E-272 T 23-10-2018 TSIB_0812 1987b50af87759744d7a11e948286164 561 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 559 2.1E-285 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSIB_1717 aa86e7802240ed3b8f49c5f48ecf00a5 192 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 161 187 2.6E-5 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1717 aa86e7802240ed3b8f49c5f48ecf00a5 192 Pfam PF00578 AhpC/TSA family 7 137 9.1E-40 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1717 aa86e7802240ed3b8f49c5f48ecf00a5 192 SUPERFAMILY SSF52833 4 191 2.25E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TSIB_1717 aa86e7802240ed3b8f49c5f48ecf00a5 192 PIRSF PIRSF000239 2 192 3.3E-65 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSIB_1717 aa86e7802240ed3b8f49c5f48ecf00a5 192 Gene3D G3DSA:3.40.30.10 3 189 8.1E-67 T 23-10-2018 TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 14 136 41.81 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 15 136 3.9E-46 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 Gene3D G3DSA:2.40.50.100 1 136 3.6E-52 T 23-10-2018 TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 Pfam PF01597 Glycine cleavage H-protein 17 137 1.0E-50 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 58 87 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSIB_0254 7fdddd00da5b71ae82182607229c8254 138 SUPERFAMILY SSF51230 14 137 3.93E-42 T 23-10-2018 IPR011053 Single hybrid motif TSIB_1819 535838e6b34b54df075f496cd579a3ac 111 Gene3D G3DSA:1.10.10.10 2 109 4.4E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_1819 535838e6b34b54df075f496cd579a3ac 111 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 6.8E-11 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TSIB_1819 535838e6b34b54df075f496cd579a3ac 111 SUPERFAMILY SSF46785 4 105 9.25E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 Gene3D G3DSA:3.40.50.1820 360 630 1.9E-83 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 SUPERFAMILY SSF82171 14 355 6.41E-27 T 23-10-2018 TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 Pfam PF07676 WD40-like Beta Propeller Repeat 62 80 0.0053 T 23-10-2018 IPR011659 WD40-like Beta Propeller TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 SUPERFAMILY SSF53474 368 613 9.47E-57 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 Gene3D G3DSA:2.120.10.30 7 202 3.0E-14 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSIB_1049 0136e1d0e17bed29b4df1741e42b737a 633 Pfam PF00326 Prolyl oligopeptidase family 403 614 2.7E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TSIB_1775 cfc8fc6569e511cd5aebfd1fdec98f5a 271 Gene3D G3DSA:3.60.15.10 1 253 3.3E-27 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1775 cfc8fc6569e511cd5aebfd1fdec98f5a 271 SUPERFAMILY SSF56281 3 253 1.49E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1775 cfc8fc6569e511cd5aebfd1fdec98f5a 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 2.9E-22 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 3 48 1.5E-9 T 23-10-2018 TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 SUPERFAMILY SSF53335 1 252 1.11E-74 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 Gene3D G3DSA:3.10.330.20 1 62 3.9E-23 T 23-10-2018 TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 232 8.5E-26 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 Gene3D G3DSA:3.40.50.150 63 253 1.3E-65 T 23-10-2018 TSIB_0929 ffe8df1c50a5f1a07e829df8fb9c87b0 253 PIRSF PIRSF017269 1 253 1.4E-76 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TSIB_0589 c02cb1f3c4ec21363de528368725ac94 150 SUPERFAMILY SSF88723 6 142 2.91E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0589 c02cb1f3c4ec21363de528368725ac94 150 Pfam PF01850 PIN domain 6 140 1.9E-10 T 23-10-2018 IPR002716 PIN domain TSIB_0589 c02cb1f3c4ec21363de528368725ac94 150 Gene3D G3DSA:3.40.50.1010 5 146 7.1E-8 T 23-10-2018 TSIB_0485 11be62bb1330eaac494107ae668ba524 191 Pfam PF05763 Protein of unknown function (DUF835) 65 186 7.2E-36 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_1621 1d4fa4dbae5a4664b129fa4c9cce07ac 433 Gene3D G3DSA:2.60.120.580 203 308 5.7E-15 T 23-10-2018 TSIB_1621 1d4fa4dbae5a4664b129fa4c9cce07ac 433 SUPERFAMILY SSF141130 12 416 5.75E-43 T 23-10-2018 TSIB_1621 1d4fa4dbae5a4664b129fa4c9cce07ac 433 Pfam PF03069 Acetamidase/Formamidase family 45 417 8.0E-60 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 TSIB_1989 b89af15045e29a0af77508d00e87aad7 240 SUPERFAMILY SSF159659 9 225 1.05E-44 T 23-10-2018 TSIB_1989 b89af15045e29a0af77508d00e87aad7 240 Pfam PF09754 PAC2 family 17 220 1.9E-42 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TSIB_1989 b89af15045e29a0af77508d00e87aad7 240 Gene3D G3DSA:3.40.50.10900 2 240 1.7E-69 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TSIB_1989 b89af15045e29a0af77508d00e87aad7 240 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 10 235 3.6E-62 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 SUPERFAMILY SSF56327 157 307 8.65E-40 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 183 189 - T 23-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 306 5.3E-24 T 23-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 Gene3D G3DSA:3.40.50.720 15 156 1.4E-54 T 23-10-2018 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PRINTS PR00086 L-lactate dehydrogenase signature 41 65 3.6E-32 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PRINTS PR00086 L-lactate dehydrogenase signature 153 171 3.6E-32 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PRINTS PR00086 L-lactate dehydrogenase signature 181 194 3.6E-32 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PRINTS PR00086 L-lactate dehydrogenase signature 129 149 3.6E-32 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PRINTS PR00086 L-lactate dehydrogenase signature 16 40 3.6E-32 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 15 155 1.3E-40 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 Gene3D G3DSA:3.90.110.10 157 308 7.3E-38 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 SUPERFAMILY SSF51735 4 155 9.79E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1633 1a6772ccea4746edb4dd26c9a908a62b 309 PIRSF PIRSF000102 11 309 1.0E-94 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSIB_1914 503c16c15e5355e1faf2b1f969e483d7 91 Pfam PF13244 Domain of unknown function (DUF4040) 11 77 3.1E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TSIB_0120 5ffd7509d479dd796c81c37d033cdc0d 202 SUPERFAMILY SSF53323 11 201 2.35E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_0120 5ffd7509d479dd796c81c37d033cdc0d 202 Gene3D G3DSA:3.40.920.10 8 202 1.6E-37 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSIB_0120 5ffd7509d479dd796c81c37d033cdc0d 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 20 198 6.9E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSIB_1793 0b0f7b5b09178a1cea155227b6d31154 102 Gene3D G3DSA:3.40.50.10580 1 102 7.2E-35 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1793 0b0f7b5b09178a1cea155227b6d31154 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 1.0E-18 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_1793 0b0f7b5b09178a1cea155227b6d31154 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.785 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TSIB_1793 0b0f7b5b09178a1cea155227b6d31154 102 SUPERFAMILY SSF159468 3 101 2.22E-20 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSIB_0914 8416ff408e2244793d93aa93c9f12074 373 Pfam PF04123 Domain of unknown function (DUF373) 1 333 2.1E-101 T 23-10-2018 IPR007254 Protein of unknown function DUF373 TSIB_1649 6697e42a0727a0396b0537fdcd161bb9 265 Pfam PF04055 Radical SAM superfamily 28 183 1.0E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSIB_1649 6697e42a0727a0396b0537fdcd161bb9 265 SUPERFAMILY SSF102114 29 196 2.94E-7 T 23-10-2018 TSIB_1649 6697e42a0727a0396b0537fdcd161bb9 265 Gene3D G3DSA:3.20.20.70 27 258 2.9E-6 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 2 80 1.2E-28 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 SUPERFAMILY SSF69786 2 91 1.05E-28 T 23-10-2018 IPR036591 YggU-like superfamily TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 SMART SM01152 5 80 2.8E-33 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 8 78 6.8E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 Hamap MF_00634 UPF0235 protein YggU [yggU]. 5 92 21.316 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TSIB_0952 149c6c7c2cc985f3e445503a3feff65d 94 Gene3D G3DSA:3.30.1200.10 1 93 2.7E-32 T 23-10-2018 IPR036591 YggU-like superfamily TSIB_2037 9e7965e36911e09860e66e8827d3a495 51 Pfam PF01583 Adenylylsulphate kinase 2 29 2.2E-6 T 23-10-2018 TSIB_2037 9e7965e36911e09860e66e8827d3a495 51 Gene3D G3DSA:3.40.50.300 1 51 8.7E-11 T 23-10-2018 TSIB_0698 47d0747b652c2dd813a32d65eb85cb79 203 Gene3D G3DSA:3.30.420.130 1 118 5.1E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_0698 47d0747b652c2dd813a32d65eb85cb79 203 SUPERFAMILY SSF53146 1 117 9.94E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_0698 47d0747b652c2dd813a32d65eb85cb79 203 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 6.2E-23 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSIB_1715 819ec9964c901ccb41fcaa53f8934e8e 140 SUPERFAMILY SSF51735 15 131 8.52E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1715 819ec9964c901ccb41fcaa53f8934e8e 140 SMART SM00881 13 105 3.7E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_1715 819ec9964c901ccb41fcaa53f8934e8e 140 Gene3D G3DSA:3.40.50.720 6 140 1.8E-43 T 23-10-2018 TSIB_1715 819ec9964c901ccb41fcaa53f8934e8e 140 Pfam PF13380 CoA binding domain 17 130 9.5E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TSIB_0758 0a33e3652ccb9dd604b3bf32b268dee3 150 Pfam PF04024 PspC domain 7 63 1.0E-19 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TSIB_0426 a65cd96fe0f4face9f437313e6b14c2f 108 SMART SM00661 25 71 0.0043 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TSIB_0426 a65cd96fe0f4face9f437313e6b14c2f 108 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 12 47 9.8E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 TSIB_1302 b12badd7057f8bd7a88245f8141daa9d 528 Pfam PF00361 Proton-conducting membrane transporter 135 448 1.2E-57 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1302 b12badd7057f8bd7a88245f8141daa9d 528 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 3.6E-8 T 23-10-2018 TSIB_1302 b12badd7057f8bd7a88245f8141daa9d 528 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 223 244 3.6E-8 T 23-10-2018 TSIB_1302 b12badd7057f8bd7a88245f8141daa9d 528 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 3.6E-8 T 23-10-2018 TSIB_1302 b12badd7057f8bd7a88245f8141daa9d 528 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 120 7.7E-10 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1494 dcf182b346334bef73cb5d0aa4d8b441 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 82 6.0E-16 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TSIB_1494 dcf182b346334bef73cb5d0aa4d8b441 85 Pfam PF09827 CRISPR associated protein Cas2 1 71 2.5E-23 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TSIB_1494 dcf182b346334bef73cb5d0aa4d8b441 85 Gene3D G3DSA:3.30.70.240 1 66 2.3E-30 T 23-10-2018 TSIB_1494 dcf182b346334bef73cb5d0aa4d8b441 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 16.16 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TSIB_1494 dcf182b346334bef73cb5d0aa4d8b441 85 SUPERFAMILY SSF143430 1 81 1.57E-25 T 23-10-2018 TSIB_1077 8e058beea118e15aac5a18795e85bd5e 388 Pfam PF07690 Major Facilitator Superfamily 9 341 4.2E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_1077 8e058beea118e15aac5a18795e85bd5e 388 Gene3D G3DSA:1.20.1250.20 1 384 6.1E-21 T 23-10-2018 TSIB_1077 8e058beea118e15aac5a18795e85bd5e 388 SUPERFAMILY SSF103473 3 380 2.49E-27 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1719 f9778bc1634e893054e55950e0a9db35 377 SUPERFAMILY SSF101960 17 356 1.19E-44 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSIB_1719 f9778bc1634e893054e55950e0a9db35 377 Pfam PF01458 Uncharacterized protein family (UPF0051) 141 349 4.1E-34 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSIB_1777 2c5c7daa98e5f0a7078a86147d198e4f 151 Pfam PF03686 Uncharacterised protein family (UPF0146) 26 142 4.0E-26 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TSIB_1777 2c5c7daa98e5f0a7078a86147d198e4f 151 Gene3D G3DSA:3.40.50.150 13 150 3.3E-24 T 23-10-2018 TSIB_1777 2c5c7daa98e5f0a7078a86147d198e4f 151 Hamap MF_00341 UPF0146 protein . 16 145 25.498 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TSIB_1777 2c5c7daa98e5f0a7078a86147d198e4f 151 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 32 125 9.0E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TSIB_2012 d725de503dd4aa76bc084375ed827143 169 Pfam PF01944 Stage II sporulation protein M 3 162 2.7E-30 T 23-10-2018 IPR002798 Stage II sporulation protein M-like TSIB_0558 056983cbbd0eea327c3024f893afcb0f 532 SUPERFAMILY SSF52540 135 496 1.02E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0558 056983cbbd0eea327c3024f893afcb0f 532 Pfam PF01935 Domain of unknown function DUF87 144 360 4.9E-38 T 23-10-2018 IPR002789 Helicase HerA, central domain TSIB_0558 056983cbbd0eea327c3024f893afcb0f 532 Pfam PF09378 HAS barrel domain 14 110 7.2E-7 T 23-10-2018 IPR018538 Helicase HerA, barrel domain TSIB_0558 056983cbbd0eea327c3024f893afcb0f 532 Gene3D G3DSA:3.40.50.300 289 499 3.5E-57 T 23-10-2018 TSIB_0558 056983cbbd0eea327c3024f893afcb0f 532 Gene3D G3DSA:3.40.50.300 128 288 7.3E-20 T 23-10-2018 TSIB_1306 2ab9c30de3d11fdd46d91c7f8a2a1b30 80 Pfam PF13244 Domain of unknown function (DUF4040) 9 74 6.1E-18 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 PIRSF PIRSF016210 7 280 4.6E-82 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 Gene3D G3DSA:3.40.50.10700 195 280 8.9E-30 T 23-10-2018 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 8 279 34.134 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 Gene3D G3DSA:3.40.630.50 4 194 5.8E-69 T 23-10-2018 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 Pfam PF04414 D-aminoacyl-tRNA deacylase 78 277 7.0E-66 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 TSIB_0378 2210cc174c374aec2ba8419db20cc369 280 SUPERFAMILY SSF142535 8 279 1.96E-86 T 23-10-2018 TSIB_1632 e2d7c084eab5749610af8748b5feddf0 133 SUPERFAMILY SSF51182 13 122 1.68E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_1632 e2d7c084eab5749610af8748b5feddf0 133 Pfam PF07883 Cupin domain 42 108 8.0E-17 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_1632 e2d7c084eab5749610af8748b5feddf0 133 Gene3D G3DSA:2.60.120.10 4 126 5.5E-24 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 8.6E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 8.6E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 8.6E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 62 6.0E-19 T 23-10-2018 TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 Gene3D G3DSA:3.30.70.20 3 67 2.1E-22 T 23-10-2018 TSIB_0128 0753224e19d378355f8c6abc4a3d56e1 67 SUPERFAMILY SSF54862 4 66 2.27E-14 T 23-10-2018 TSIB_0809 625ac39d7bbeef71ff2b5e2ed8ed18da 312 SUPERFAMILY SSF52540 3 224 2.61E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0809 625ac39d7bbeef71ff2b5e2ed8ed18da 312 SMART SM00382 29 229 1.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0809 625ac39d7bbeef71ff2b5e2ed8ed18da 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0809 625ac39d7bbeef71ff2b5e2ed8ed18da 312 Gene3D G3DSA:3.40.50.300 1 238 3.4E-59 T 23-10-2018 TSIB_0809 625ac39d7bbeef71ff2b5e2ed8ed18da 312 Pfam PF00005 ABC transporter 23 164 1.1E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0518 8fbcb6f63f024279dcac37de22614b84 44 SUPERFAMILY SSF55298 16 44 3.14E-5 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSIB_0551 8d79d02bf1ae6d3f94fbb5220d3cef8c 265 PIRSF PIRSF004853 4 257 4.6E-115 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TSIB_0551 8d79d02bf1ae6d3f94fbb5220d3cef8c 265 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 74 255 1.0E-82 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TSIB_0551 8d79d02bf1ae6d3f94fbb5220d3cef8c 265 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 69 244 5.5E-76 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TSIB_0551 8d79d02bf1ae6d3f94fbb5220d3cef8c 265 Gene3D G3DSA:3.40.50.12640 4 264 6.3E-121 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 Pfam PF00483 Nucleotidyl transferase 2 272 1.4E-61 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 Pfam PF01050 Mannose-6-phosphate isomerase 305 455 8.0E-66 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 Gene3D G3DSA:2.60.120.10 344 452 1.2E-17 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 458 3.1E-156 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 Gene3D G3DSA:3.90.550.10 1 339 3.4E-113 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 SUPERFAMILY SSF53448 1 267 2.17E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0249 a09bc25616b79e7133d0d9b871011e78 460 SUPERFAMILY SSF51182 185 459 1.23E-65 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_0556 78f67dc7ea3d67a902acc7dc72ee1ca4 384 SUPERFAMILY SSF56300 1 289 2.28E-45 T 23-10-2018 TSIB_0556 78f67dc7ea3d67a902acc7dc72ee1ca4 384 Gene3D G3DSA:3.60.21.10 1 245 2.5E-55 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0556 78f67dc7ea3d67a902acc7dc72ee1ca4 384 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 382 24.105 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 TSIB_0556 78f67dc7ea3d67a902acc7dc72ee1ca4 384 Pfam PF00149 Calcineurin-like phosphoesterase 1 189 6.0E-13 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_1259 c616b8d230b328f8f4d56ab4dc0d1943 193 SUPERFAMILY SSF53448 12 120 2.35E-6 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1259 c616b8d230b328f8f4d56ab4dc0d1943 193 Gene3D G3DSA:3.90.550.10 11 192 2.6E-11 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1973 8da290de8892b7be24ea6d9083f03419 206 Pfam PF00174 Oxidoreductase molybdopterin binding domain 54 187 2.1E-26 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSIB_1973 8da290de8892b7be24ea6d9083f03419 206 SUPERFAMILY SSF56524 26 198 1.15E-37 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSIB_1973 8da290de8892b7be24ea6d9083f03419 206 Gene3D G3DSA:3.90.420.10 19 205 1.5E-30 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSIB_1340 07a2109bad5007a07cf221ae6a4298f8 102 Pfam PF11419 Protein of unknown function (DUF3194) 9 90 1.1E-25 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 TSIB_1340 07a2109bad5007a07cf221ae6a4298f8 102 Gene3D G3DSA:3.30.300.100 1 102 2.3E-35 T 23-10-2018 IPR035954 MTH677-like superfamily TSIB_1418 a000a9832c778d7cca72533b5e7c8896 108 SUPERFAMILY SSF51182 1 100 1.69E-22 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_1418 a000a9832c778d7cca72533b5e7c8896 108 Pfam PF07883 Cupin domain 41 91 2.1E-10 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_1418 a000a9832c778d7cca72533b5e7c8896 108 Gene3D G3DSA:2.60.120.10 2 102 4.3E-29 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0073 e9c4e5915bb079a1787f41cd11f2f272 205 Gene3D G3DSA:3.40.50.150 1 204 2.8E-69 T 23-10-2018 TSIB_0073 e9c4e5915bb079a1787f41cd11f2f272 205 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSIB_0073 e9c4e5915bb079a1787f41cd11f2f272 205 SUPERFAMILY SSF53335 3 202 1.61E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0073 e9c4e5915bb079a1787f41cd11f2f272 205 Pfam PF05175 Methyltransferase small domain 42 126 2.8E-14 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSIB_0950 396f77db470d05955c80315f8e813711 276 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 254 3.5E-56 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSIB_0950 396f77db470d05955c80315f8e813711 276 PIRSF PIRSF016184 3 276 8.6E-68 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSIB_0950 396f77db470d05955c80315f8e813711 276 SUPERFAMILY SSF54506 6 274 5.18E-68 T 23-10-2018 TSIB_0950 396f77db470d05955c80315f8e813711 276 Gene3D G3DSA:3.10.310.10 4 124 3.8E-36 T 23-10-2018 TSIB_0950 396f77db470d05955c80315f8e813711 276 Gene3D G3DSA:3.10.310.10 125 265 2.1E-34 T 23-10-2018 TSIB_0950 396f77db470d05955c80315f8e813711 276 Pfam PF02567 Phenazine biosynthesis-like protein 11 257 2.3E-59 T 23-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSIB_0649 1deb2a0002425398f96d5a42a34f9e73 308 SUPERFAMILY SSF51735 1 305 5.44E-98 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_0649 1deb2a0002425398f96d5a42a34f9e73 308 Gene3D G3DSA:3.40.50.720 9 290 1.1E-105 T 23-10-2018 TSIB_0649 1deb2a0002425398f96d5a42a34f9e73 308 Gene3D G3DSA:3.90.25.10 169 302 1.1E-105 T 23-10-2018 TSIB_0649 1deb2a0002425398f96d5a42a34f9e73 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 237 7.4E-63 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSIB_0933 f6cba2b6428cb7f47ea4ab50489b3b6e 439 Gene3D G3DSA:3.30.2290.10 4 211 2.1E-21 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSIB_0933 f6cba2b6428cb7f47ea4ab50489b3b6e 439 SUPERFAMILY SSF111283 6 433 1.29E-83 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSIB_0933 f6cba2b6428cb7f47ea4ab50489b3b6e 439 Pfam PF01523 Putative modulator of DNA gyrase 21 314 1.7E-49 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 Pfam PF01282 Ribosomal protein S24e 21 97 7.7E-26 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 74 5.0E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 SUPERFAMILY SSF54189 1 97 5.4E-31 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.113 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0029 982f8ac486fc5e720b3c33e2b7ab50bd 98 Gene3D G3DSA:3.30.70.330 1 98 5.0E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 Pfam PF00294 pfkB family carbohydrate kinase 2 293 7.8E-53 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 PRINTS PR00990 Ribokinase signature 211 222 1.6E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 PRINTS PR00990 Ribokinase signature 178 193 1.6E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 PRINTS PR00990 Ribokinase signature 26 45 1.6E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 Gene3D G3DSA:3.40.1190.20 1 308 1.1E-101 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 31 55 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSIB_0357 5963a5bf015fbb84a4eec334c021048d 311 SUPERFAMILY SSF53613 2 303 2.03E-66 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0087 32ed444876b98c82d53da7715e317654 136 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 10 134 3.3E-52 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TSIB_0087 32ed444876b98c82d53da7715e317654 136 Gene3D G3DSA:3.30.1330.40 4 136 2.2E-55 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSIB_0087 32ed444876b98c82d53da7715e317654 136 Pfam PF01042 Endoribonuclease L-PSP 14 134 4.4E-45 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSIB_0087 32ed444876b98c82d53da7715e317654 136 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 111 129 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TSIB_0087 32ed444876b98c82d53da7715e317654 136 SUPERFAMILY SSF55298 7 135 2.2E-47 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSIB_0762 5703ae0cdc872584dbed89dd9d274f55 147 SMART SM00232 17 144 1.8E-9 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TSIB_0762 5703ae0cdc872584dbed89dd9d274f55 147 Gene3D G3DSA:3.40.140.10 18 147 1.2E-26 T 23-10-2018 TSIB_0762 5703ae0cdc872584dbed89dd9d274f55 147 SUPERFAMILY SSF102712 17 141 6.41E-20 T 23-10-2018 TSIB_0762 5703ae0cdc872584dbed89dd9d274f55 147 Pfam PF14464 Prokaryotic homologs of the JAB domain 30 125 1.9E-15 T 23-10-2018 IPR028090 JAB domain, prokaryotic TSIB_0709 2528b3be70d5db781c3acf9c5c89b488 267 Pfam PF01336 OB-fold nucleic acid binding domain 45 115 3.6E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSIB_0709 2528b3be70d5db781c3acf9c5c89b488 267 Gene3D G3DSA:2.40.50.140 7 138 2.7E-11 T 23-10-2018 TSIB_0709 2528b3be70d5db781c3acf9c5c89b488 267 SUPERFAMILY SSF50249 10 131 4.06E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0598 0da0a1a064c32291f1ab8441a6d72fbb 518 Pfam PF05124 S-layer like family, C-terminal region 421 515 6.5E-9 T 23-10-2018 IPR022651 S-layer protein, C-terminal TSIB_1084 18b79569c095b7d2c08b10f0a4f40436 536 SUPERFAMILY SSF54001 251 401 3.43E-10 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSIB_1084 18b79569c095b7d2c08b10f0a4f40436 536 Pfam PF01841 Transglutaminase-like superfamily 298 389 3.7E-5 T 23-10-2018 IPR002931 Transglutaminase-like TSIB_1084 18b79569c095b7d2c08b10f0a4f40436 536 Gene3D G3DSA:3.10.620.30 258 403 4.2E-6 T 23-10-2018 TSIB_0484 211d6245c79678ee8223ac07506f2cf0 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 105 3.6E-38 T 23-10-2018 IPR003793 Domain of unknown function DUF190 TSIB_0484 211d6245c79678ee8223ac07506f2cf0 126 Gene3D G3DSA:3.30.70.120 1 126 2.7E-58 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSIB_0484 211d6245c79678ee8223ac07506f2cf0 126 SUPERFAMILY SSF54913 8 107 1.56E-33 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSIB_0912 498dc2f74466b4c07c29284acf0866d6 281 SMART SM00518 4 276 2.0E-79 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TSIB_0912 498dc2f74466b4c07c29284acf0866d6 281 SUPERFAMILY SSF51658 7 278 3.37E-59 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TSIB_0912 498dc2f74466b4c07c29284acf0866d6 281 Gene3D G3DSA:3.20.20.150 12 280 4.4E-44 T 23-10-2018 TSIB_0912 498dc2f74466b4c07c29284acf0866d6 281 Pfam PF01261 Xylose isomerase-like TIM barrel 28 239 4.5E-21 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 SUPERFAMILY SSF56281 3 253 7.47E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 SUPERFAMILY SSF52218 259 406 3.62E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 SMART SM00849 39 207 8.2E-29 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 PIRSF PIRSF005243 3 408 8.5E-114 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 Gene3D G3DSA:3.60.15.10 1 256 1.6E-92 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 Pfam PF00753 Metallo-beta-lactamase superfamily 41 182 7.8E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1899 85a3c0505cffceea9b9375da866939e6 408 Gene3D G3DSA:3.40.50.360 257 405 4.5E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 Gene3D G3DSA:3.40.1160.10 1 225 1.2E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 35.094 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 PIRSF PIRSF005650 1 225 1.4E-62 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 Pfam PF00696 Amino acid kinase family 1 202 4.0E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 SUPERFAMILY SSF53633 1 224 1.22E-50 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1322 d1032e067e2f94c28a2706a6fd7bcb96 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 4.9E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TSIB_1582 06510f95de1cdeef6e8ddcab72fd9034 163 Pfam PF01230 HIT domain 35 125 2.6E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TSIB_1582 06510f95de1cdeef6e8ddcab72fd9034 163 Gene3D G3DSA:3.30.428.10 1 162 1.8E-56 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_1582 06510f95de1cdeef6e8ddcab72fd9034 163 SUPERFAMILY SSF54197 1 159 2.04E-44 T 23-10-2018 IPR036265 HIT-like superfamily TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 Pfam PF09378 HAS barrel domain 4 93 3.4E-10 T 23-10-2018 IPR018538 Helicase HerA, barrel domain TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 Pfam PF05872 Bacterial protein of unknown function (DUF853) 403 503 3.8E-5 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 Pfam PF01935 Domain of unknown function DUF87 139 372 3.1E-43 T 23-10-2018 IPR002789 Helicase HerA, central domain TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 SUPERFAMILY SSF52540 136 522 3.02E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 Gene3D G3DSA:3.40.50.300 311 532 5.5E-55 T 23-10-2018 TSIB_0094 787b881ddcc543bcd07acec39c3fa700 555 Gene3D G3DSA:3.40.50.300 126 269 1.3E-24 T 23-10-2018 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 Pfam PF01198 Ribosomal protein L31e 5 74 7.4E-14 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 Gene3D G3DSA:3.10.440.10 1 86 1.9E-27 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 21 54 9.0E-10 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 SMART SM01380 4 81 1.1E-26 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 1 84 20.145 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0645 e5d2c74bd97f2395dd3b6afaa63837a3 86 SUPERFAMILY SSF54575 3 79 3.53E-24 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 SUPERFAMILY SSF54919 12 160 4.19E-61 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 12 150 36.198 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 Pfam PF00334 Nucleoside diphosphate kinase 13 149 6.5E-58 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 PRINTS PR01243 Nucleoside diphosphate kinase signature 79 96 4.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 PRINTS PR01243 Nucleoside diphosphate kinase signature 59 78 4.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 PRINTS PR01243 Nucleoside diphosphate kinase signature 100 116 4.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 PRINTS PR01243 Nucleoside diphosphate kinase signature 15 37 4.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 PRINTS PR01243 Nucleoside diphosphate kinase signature 126 145 4.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 SMART SM00562 12 152 4.9E-84 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 Gene3D G3DSA:3.30.70.141 6 164 5.3E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSIB_0535 bb4b13292712921f0e91d946785bf51b 164 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 126 134 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSIB_1297 1b6e24aaad1a9454adcba89766f91b0c 329 Pfam PF00146 NADH dehydrogenase 11 320 4.9E-59 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 Gene3D G3DSA:2.20.25.420 5 55 1.2E-6 T 23-10-2018 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 Pfam PF03367 ZPR1 zinc-finger domain 11 167 1.5E-40 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 11 192 5.3E-61 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 SMART SM00709 10 170 1.3E-75 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 12 177 5.0E-71 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 TSIB_1479 fbf3b22e1f9668bcaf25950faf3a34b2 201 Gene3D G3DSA:2.60.120.1040 58 183 1.4E-22 T 23-10-2018 TSIB_0734 212d69b06b8d510d2aceaace60f3448d 178 Gene3D G3DSA:3.40.50.1950 3 178 8.4E-41 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0734 212d69b06b8d510d2aceaace60f3448d 178 SUPERFAMILY SSF52507 5 171 1.13E-25 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSIB_0734 212d69b06b8d510d2aceaace60f3448d 178 Pfam PF02441 Flavoprotein 6 164 2.9E-17 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSIB_0927 bd0ca7ff400bcecccfb3a11aeee41f6e 105 Pfam PF01922 SRP19 protein 8 94 1.1E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_0927 bd0ca7ff400bcecccfb3a11aeee41f6e 105 Gene3D G3DSA:3.30.56.30 4 104 2.8E-30 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_0927 bd0ca7ff400bcecccfb3a11aeee41f6e 105 SUPERFAMILY SSF69695 5 100 2.22E-19 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSIB_0892 a75fa0af8482b38e30e6d3af2dd6ce2b 226 Gene3D G3DSA:1.10.150.520 21 95 7.2E-29 T 23-10-2018 TSIB_0892 a75fa0af8482b38e30e6d3af2dd6ce2b 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 189 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSIB_0892 a75fa0af8482b38e30e6d3af2dd6ce2b 226 SUPERFAMILY SSF56784 5 221 1.09E-38 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0892 a75fa0af8482b38e30e6d3af2dd6ce2b 226 Gene3D G3DSA:3.40.50.1000 8 214 7.2E-29 T 23-10-2018 IPR023214 HAD superfamily TSIB_0892 a75fa0af8482b38e30e6d3af2dd6ce2b 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 195 2.5E-22 T 23-10-2018 TSIB_0511 e19b13a3e623739fcc0493ae1b8c0f22 76 Pfam PF01423 LSM domain 8 72 4.2E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TSIB_0511 e19b13a3e623739fcc0493ae1b8c0f22 76 SUPERFAMILY SSF50182 5 74 9.31E-19 T 23-10-2018 IPR010920 LSM domain superfamily TSIB_0511 e19b13a3e623739fcc0493ae1b8c0f22 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 24.304 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea TSIB_0511 e19b13a3e623739fcc0493ae1b8c0f22 76 Gene3D G3DSA:2.30.30.100 1 74 9.7E-24 T 23-10-2018 TSIB_0511 e19b13a3e623739fcc0493ae1b8c0f22 76 SMART SM00651 7 72 7.8E-21 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TSIB_1136 a4704aa92c25eaff11a39093f24c0a5d 73 Gene3D G3DSA:3.10.20.30 1 73 2.8E-12 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1136 a4704aa92c25eaff11a39093f24c0a5d 73 Pfam PF02597 ThiS family 5 73 2.0E-10 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1136 a4704aa92c25eaff11a39093f24c0a5d 73 SUPERFAMILY SSF54285 15 73 1.42E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_1310 eacfafb974024aa1a8c5f1fe0cb356a3 71 Pfam PF01938 TRAM domain 15 71 9.0E-15 T 23-10-2018 IPR002792 TRAM domain TSIB_1310 eacfafb974024aa1a8c5f1fe0cb356a3 71 SUPERFAMILY SSF50249 10 71 2.0E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1310 eacfafb974024aa1a8c5f1fe0cb356a3 71 Gene3D G3DSA:2.40.50.140 6 71 1.8E-26 T 23-10-2018 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 213 1.8E-89 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 PIRSF PIRSF001357 1 219 1.2E-87 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 Gene3D G3DSA:3.20.20.70 1 219 2.9E-104 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 217 38.462 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 SMART SM01133 2 215 1.6E-110 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 SUPERFAMILY SSF51569 1 216 1.36E-90 T 23-10-2018 TSIB_1148 388496ecb6489c5ef0f850621c2910c5 219 Pfam PF01791 DeoC/LacD family aldolase 3 212 4.9E-21 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 Gene3D G3DSA:3.40.50.920 253 391 4.4E-36 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 SUPERFAMILY SSF52518 4 251 4.77E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 1.3E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 SUPERFAMILY SSF52922 252 371 2.75E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 364 1.2E-24 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TSIB_1379 ad164581310e2fe85e4bc82ab6b26036 394 Gene3D G3DSA:3.40.50.970 1 252 2.0E-105 T 23-10-2018 TSIB_0666 d9f8aaff6066ee5411d002ba61d8bb2c 274 SUPERFAMILY SSF51717 7 271 3.79E-79 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_0666 d9f8aaff6066ee5411d002ba61d8bb2c 274 Pfam PF00809 Pterin binding enzyme 14 254 2.0E-61 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_0666 d9f8aaff6066ee5411d002ba61d8bb2c 274 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 267 1.7E-73 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TSIB_0666 d9f8aaff6066ee5411d002ba61d8bb2c 274 Gene3D G3DSA:3.20.20.20 2 273 2.3E-86 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSIB_0167 22afb7d7b5152447a6e685350ce29149 214 Gene3D G3DSA:2.130.10.10 4 214 1.7E-9 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSIB_0167 22afb7d7b5152447a6e685350ce29149 214 SUPERFAMILY SSF50998 52 210 8.63E-11 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_0167 22afb7d7b5152447a6e685350ce29149 214 Pfam PF13360 PQQ-like domain 89 183 3.9E-5 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 SUPERFAMILY SSF116734 232 434 1.11E-40 T 23-10-2018 TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 Pfam PF01420 Type I restriction modification DNA specificity domain 36 205 9.0E-32 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 Pfam PF01420 Type I restriction modification DNA specificity domain 234 402 4.3E-16 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 Gene3D G3DSA:3.90.220.20 12 206 2.1E-45 T 23-10-2018 TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 SUPERFAMILY SSF116734 24 223 1.13E-49 T 23-10-2018 TSIB_1612 78ae1c3319c56427c8c5da61b9abc669 434 Gene3D G3DSA:3.90.220.20 231 434 3.8E-42 T 23-10-2018 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 Gene3D G3DSA:3.10.20.30 319 397 1.5E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_0509 be718d086c5854467cccff8d609c10d4 397 SUPERFAMILY SSF81271 323 393 1.44E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 SUPERFAMILY SSF52540 1 315 1.94E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0509 be718d086c5854467cccff8d609c10d4 397 Pfam PF01926 50S ribosome-binding GTPase 2 132 3.4E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 8.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 8.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 8.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 8.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 Gene3D G3DSA:1.10.8.470 126 215 1.9E-31 T 23-10-2018 TSIB_0509 be718d086c5854467cccff8d609c10d4 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 6.9E-35 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal TSIB_0509 be718d086c5854467cccff8d609c10d4 397 Pfam PF02824 TGS domain 345 393 1.2E-12 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 Gene3D G3DSA:3.50.50.60 107 431 3.6E-146 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 7.8E-18 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 7.8E-18 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 7.8E-18 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.8E-18 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 283 4.4E-66 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 SUPERFAMILY SSF51905 1 336 4.16E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 3.6E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 Gene3D G3DSA:3.50.50.60 2 331 3.6E-146 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 8.9E-25 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 8.9E-25 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 8.9E-25 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 8.9E-25 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 8.9E-25 T 23-10-2018 TSIB_1323 da6430b7da6595b7186ff153b832de1f 439 SUPERFAMILY SSF55424 316 436 2.58E-28 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSIB_1001 62986fbf50c7aa584aa455c2f33c4bf9 263 Gene3D G3DSA:3.20.20.150 6 254 2.2E-24 T 23-10-2018 TSIB_1001 62986fbf50c7aa584aa455c2f33c4bf9 263 SUPERFAMILY SSF51658 18 262 5.8E-20 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TSIB_1138 fcc016e818c560a737c5f1760eb3b066 599 Pfam PF03065 Glycosyl hydrolase family 57 105 324 1.3E-7 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TSIB_1138 fcc016e818c560a737c5f1760eb3b066 599 SUPERFAMILY SSF88713 5 269 2.15E-20 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSIB_1138 fcc016e818c560a737c5f1760eb3b066 599 Gene3D G3DSA:3.20.110.20 46 310 2.6E-9 T 23-10-2018 TSIB_0014 588fc663d1825365ebe650d44e217d59 475 Pfam PF03008 Archaea bacterial proteins of unknown function 315 419 8.1E-24 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TSIB_0014 588fc663d1825365ebe650d44e217d59 475 Pfam PF01637 ATPase domain predominantly from Archaea 3 203 8.4E-14 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TSIB_0014 588fc663d1825365ebe650d44e217d59 475 Gene3D G3DSA:3.40.50.300 1 168 6.9E-27 T 23-10-2018 TSIB_0014 588fc663d1825365ebe650d44e217d59 475 SUPERFAMILY SSF52540 1 244 1.11E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1364 ae721b0626a29115b47778c21afd738a 297 Pfam PF12773 Double zinc ribbon 253 296 3.4E-8 T 23-10-2018 IPR025874 Double zinc ribbon TSIB_1382 fb2212929ec9073e49d14091947212bd 393 Gene3D G3DSA:3.40.50.920 253 393 1.4E-42 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1382 fb2212929ec9073e49d14091947212bd 393 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 263 366 4.0E-32 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TSIB_1382 fb2212929ec9073e49d14091947212bd 393 SUPERFAMILY SSF52518 1 251 2.47E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1382 fb2212929ec9073e49d14091947212bd 393 Gene3D G3DSA:3.40.50.970 2 252 4.5E-102 T 23-10-2018 TSIB_1382 fb2212929ec9073e49d14091947212bd 393 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 240 2.5E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSIB_1382 fb2212929ec9073e49d14091947212bd 393 SUPERFAMILY SSF52922 254 375 2.75E-34 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1605 6faee603ddcbbba57cd238d33c1098f4 446 Gene3D G3DSA:3.40.1480.10 278 442 5.3E-167 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TSIB_1605 6faee603ddcbbba57cd238d33c1098f4 446 Pfam PF05161 MOFRL family 333 438 2.6E-35 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TSIB_1605 6faee603ddcbbba57cd238d33c1098f4 446 Gene3D G3DSA:3.40.50.10180 35 277 5.3E-167 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TSIB_1605 6faee603ddcbbba57cd238d33c1098f4 446 SUPERFAMILY SSF82544 16 445 3.14E-138 T 23-10-2018 TSIB_1605 6faee603ddcbbba57cd238d33c1098f4 446 Pfam PF13660 Domain of unknown function (DUF4147) 20 253 5.5E-82 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TSIB_0711 2a4d4f2d7fd3fc292d97d72e88eb0bec 279 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.177 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 TSIB_0711 2a4d4f2d7fd3fc292d97d72e88eb0bec 279 Gene3D G3DSA:1.10.357.140 11 156 1.1E-15 T 23-10-2018 TSIB_0711 2a4d4f2d7fd3fc292d97d72e88eb0bec 279 Pfam PF01040 UbiA prenyltransferase family 23 256 3.5E-44 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSIB_1550 1adb29bf168b4ddb612ad3d4fc58aa0f 717 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 599 672 3.0E-14 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TSIB_1550 1adb29bf168b4ddb612ad3d4fc58aa0f 717 Gene3D G3DSA:2.60.40.1120 398 468 3.1E-10 T 23-10-2018 TSIB_1550 1adb29bf168b4ddb612ad3d4fc58aa0f 717 SUPERFAMILY SSF49464 399 473 3.73E-10 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TSIB_1550 1adb29bf168b4ddb612ad3d4fc58aa0f 717 Pfam PF13620 Carboxypeptidase regulatory-like domain 397 467 2.0E-8 T 23-10-2018 TSIB_1520 c58b414ab2ca2b4e46d664d0756e3ce7 337 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 309 320 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1520 c58b414ab2ca2b4e46d664d0756e3ce7 337 Pfam PF17179 4Fe-4S dicluster domain 232 323 4.5E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1520 c58b414ab2ca2b4e46d664d0756e3ce7 337 Gene3D G3DSA:1.10.1060.10 283 336 1.1E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1520 c58b414ab2ca2b4e46d664d0756e3ce7 337 SUPERFAMILY SSF46548 224 334 2.49E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 Pfam PF03168 Late embryogenesis abundant protein 188 275 5.7E-10 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 SMART SM00769 167 287 3.9E-17 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 Gene3D G3DSA:2.60.40.10 166 297 1.7E-27 T 23-10-2018 IPR013783 Immunoglobulin-like fold TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 Gene3D G3DSA:2.60.40.10 34 152 1.7E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 SUPERFAMILY SSF117070 162 271 3.14E-16 T 23-10-2018 TSIB_1844 a8c35871a27e453c8d78dbbbe9a50dfc 300 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 184 239 0.009 T 23-10-2018 TSIB_0086 40f12469b4bbe92c52a8581404c4927d 113 Pfam PF03788 LrgA family 13 104 3.3E-31 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 TSIB_1470 65860447ee82c9e2652c124a792020c0 287 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 204 3.1E-37 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSIB_1470 65860447ee82c9e2652c124a792020c0 287 Gene3D G3DSA:3.40.50.970 67 253 1.7E-30 T 23-10-2018 TSIB_1470 65860447ee82c9e2652c124a792020c0 287 SUPERFAMILY SSF52518 19 270 6.61E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_2052 2061f812c1680fcd73efd8304fba00b2 333 Pfam PF13480 Acetyltransferase (GNAT) domain 172 298 1.8E-8 T 23-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSIB_2052 2061f812c1680fcd73efd8304fba00b2 333 Gene3D G3DSA:3.40.630.30 157 318 3.6E-8 T 23-10-2018 TSIB_2052 2061f812c1680fcd73efd8304fba00b2 333 SUPERFAMILY SSF55729 166 325 7.55E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 Gene3D G3DSA:1.20.1430.10 420 566 2.2E-49 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 SUPERFAMILY SSF88713 2 419 4.45E-125 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 SUPERFAMILY SSF88688 419 536 5.56E-35 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 Pfam PF09210 Domain of unknown function (DUF1957) 430 535 1.1E-30 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 Gene3D G3DSA:3.20.110.10 1 419 3.4E-172 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TSIB_1115 3a34ed0e6c1289c493b7e9fc4a47363c 566 Pfam PF03065 Glycosyl hydrolase family 57 6 384 1.5E-81 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TSIB_1840 7f6653cda7ab8dbdf44529b9c0541d29 276 Gene3D G3DSA:2.60.200.30 121 252 2.1E-71 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSIB_1840 7f6653cda7ab8dbdf44529b9c0541d29 276 SUPERFAMILY SSF111331 2 268 7.33E-73 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSIB_1840 7f6653cda7ab8dbdf44529b9c0541d29 276 Gene3D G3DSA:3.40.50.10330 20 265 2.1E-71 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSIB_1840 7f6653cda7ab8dbdf44529b9c0541d29 276 Pfam PF01513 ATP-NAD kinase 2 259 2.8E-67 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSIB_1840 7f6653cda7ab8dbdf44529b9c0541d29 276 Hamap MF_00361 NAD kinase [nadK]. 1 274 30.182 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 713 743 0.0092 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 168 198 0.031 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 608 638 0.018 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 660 690 0.031 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 SUPERFAMILY SSF75011 46 339 1.28E-19 T 23-10-2018 TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Gene3D G3DSA:2.80.10.50 625 753 6.7E-9 T 23-10-2018 TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 SUPERFAMILY SSF50998 481 828 6.67E-16 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 Gene3D G3DSA:2.130.10.10 29 381 1.0E-9 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 654 690 0.0026 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 54 94 0.0012 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 212 250 0.0063 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 600 638 2.0E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 704 742 3.8E-4 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 159 198 0.0056 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_1448 e7376fb1df7ca01aecae42d0b7b62931 974 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 756 794 0.002 T 23-10-2018 IPR013431 Delta-60 repeat TSIB_0206 de87af76799b35c5efb96268f1ea5a04 235 Gene3D G3DSA:3.30.1490.20 38 115 2.6E-88 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_0206 de87af76799b35c5efb96268f1ea5a04 235 Pfam PF13549 ATP-grasp domain 12 234 1.3E-77 T 23-10-2018 TSIB_0206 de87af76799b35c5efb96268f1ea5a04 235 SUPERFAMILY SSF56059 18 234 5.3E-45 T 23-10-2018 TSIB_0206 de87af76799b35c5efb96268f1ea5a04 235 Gene3D G3DSA:3.30.470.20 17 232 2.6E-88 T 23-10-2018 TSIB_0350 64e2abb1b1c45b239fbb2a75a3a4b9d9 202 Pfam PF00881 Nitroreductase family 7 181 2.8E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_0350 64e2abb1b1c45b239fbb2a75a3a4b9d9 202 SUPERFAMILY SSF55469 1 201 1.03E-40 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_0350 64e2abb1b1c45b239fbb2a75a3a4b9d9 202 Gene3D G3DSA:3.40.109.10 1 201 7.1E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1441 b5f9e880bdbe7e47e1024240cfc9062e 253 SMART SM00382 26 209 3.5E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1441 b5f9e880bdbe7e47e1024240cfc9062e 253 Gene3D G3DSA:3.40.50.300 1 242 6.1E-67 T 23-10-2018 TSIB_1441 b5f9e880bdbe7e47e1024240cfc9062e 253 SUPERFAMILY SSF52540 1 222 2.77E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1441 b5f9e880bdbe7e47e1024240cfc9062e 253 Pfam PF00005 ABC transporter 17 161 7.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1459 653a6cfe18ec0cec609db70b11b4428a 243 Gene3D G3DSA:3.40.50.300 9 241 9.0E-62 T 23-10-2018 TSIB_1459 653a6cfe18ec0cec609db70b11b4428a 243 SUPERFAMILY SSF52540 11 216 1.23E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1459 653a6cfe18ec0cec609db70b11b4428a 243 SMART SM00382 30 205 1.2E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1459 653a6cfe18ec0cec609db70b11b4428a 243 Pfam PF00005 ABC transporter 21 158 1.3E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1121 85b661d217b50d99f2a91272fda48bde 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 435 6.1E-84 T 23-10-2018 TSIB_1121 85b661d217b50d99f2a91272fda48bde 650 Pfam PF05670 Domain of unknown function (DUF814) 455 552 9.0E-27 T 23-10-2018 IPR008532 Domain of unknown function DUF814 TSIB_1121 85b661d217b50d99f2a91272fda48bde 650 SUPERFAMILY SSF46946 158 223 4.84E-7 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSIB_1121 85b661d217b50d99f2a91272fda48bde 650 Gene3D G3DSA:2.30.310.10 5 151 8.1E-34 T 23-10-2018 TSIB_1365 ec599fcc56b1884591c042060703390f 351 Gene3D G3DSA:1.20.120.1190 1 161 6.6E-55 T 23-10-2018 TSIB_1365 ec599fcc56b1884591c042060703390f 351 SUPERFAMILY SSF52540 168 340 9.02E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1365 ec599fcc56b1884591c042060703390f 351 Gene3D G3DSA:3.40.50.300 162 348 1.7E-52 T 23-10-2018 TSIB_1365 ec599fcc56b1884591c042060703390f 351 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 327 1.1E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1365 ec599fcc56b1884591c042060703390f 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 6.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1365 ec599fcc56b1884591c042060703390f 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 6.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1365 ec599fcc56b1884591c042060703390f 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 6.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1365 ec599fcc56b1884591c042060703390f 351 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 8.8E-25 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 TSIB_1076 8b7878ec849ab4e57698bbbff485faf8 148 Pfam PF00583 Acetyltransferase (GNAT) family 26 137 2.2E-13 T 23-10-2018 IPR000182 GNAT domain TSIB_1076 8b7878ec849ab4e57698bbbff485faf8 148 SUPERFAMILY SSF55729 10 142 1.3E-19 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_1076 8b7878ec849ab4e57698bbbff485faf8 148 Gene3D G3DSA:3.40.630.30 1 137 9.1E-34 T 23-10-2018 TSIB_1171 8c9338989d9b45beb50038950f53aa74 224 Pfam PF09968 Uncharacterized protein domain (DUF2202) 64 223 3.8E-63 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TSIB_1171 8c9338989d9b45beb50038950f53aa74 224 Gene3D G3DSA:1.20.1260.10 59 224 1.3E-66 T 23-10-2018 IPR012347 Ferritin-like TSIB_1171 8c9338989d9b45beb50038950f53aa74 224 SUPERFAMILY SSF47240 62 200 8.59E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 Gene3D G3DSA:3.10.580.10 4 139 4.2E-47 T 23-10-2018 TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 Pfam PF00571 CBS domain 75 127 9.1E-14 T 23-10-2018 IPR000644 CBS domain TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 Pfam PF00571 CBS domain 14 64 8.3E-13 T 23-10-2018 IPR000644 CBS domain TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 SUPERFAMILY SSF54631 8 127 6.82E-33 T 23-10-2018 TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 SMART SM00116 82 129 3.2E-7 T 23-10-2018 IPR000644 CBS domain TSIB_0158 6a2cad1e853df9bc54982e37d90815ee 139 SMART SM00116 18 65 3.5E-12 T 23-10-2018 IPR000644 CBS domain TSIB_0287 d5061a094158bdf77236a67a089ca1fd 261 SUPERFAMILY SSF75217 6 259 6.4E-46 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TSIB_0287 d5061a094158bdf77236a67a089ca1fd 261 Gene3D G3DSA:3.40.1280.10 8 257 2.0E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSIB_0287 d5061a094158bdf77236a67a089ca1fd 261 Gene3D G3DSA:2.40.50.140 94 159 2.0E-75 T 23-10-2018 TSIB_0287 d5061a094158bdf77236a67a089ca1fd 261 SUPERFAMILY SSF50249 94 159 1.88E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0287 d5061a094158bdf77236a67a089ca1fd 261 Pfam PF02598 Putative RNA methyltransferase 7 254 1.9E-51 T 23-10-2018 IPR003750 Putative RNA methyltransferase TSIB_1266 5bef3beb505ef120202234519f093f77 233 Pfam PF01940 Integral membrane protein DUF92 8 210 1.8E-51 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 TSIB_0873 aa019b87e9fc9deea2939879d0522955 501 SUPERFAMILY SSF69304 89 230 6.54E-5 T 23-10-2018 TSIB_0873 aa019b87e9fc9deea2939879d0522955 501 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 41 374 4.7E-163 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TSIB_0873 aa019b87e9fc9deea2939879d0522955 501 PIRSF PIRSF016666 11 501 1.1E-234 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TSIB_0940 373ca229d7ac08a33f897d309d54430f 241 PIRSF PIRSF016933 13 233 1.2E-35 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 TSIB_0940 373ca229d7ac08a33f897d309d54430f 241 Pfam PF13367 Protease prsW family 40 212 2.4E-31 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 TSIB_2008 3f9d3aa982736607d942d0fc46f23a88 441 Gene3D G3DSA:1.20.1250.20 36 418 5.8E-37 T 23-10-2018 TSIB_2008 3f9d3aa982736607d942d0fc46f23a88 441 SUPERFAMILY SSF103473 39 424 4.19E-38 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_2008 3f9d3aa982736607d942d0fc46f23a88 441 Pfam PF07690 Major Facilitator Superfamily 44 380 7.8E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 SUPERFAMILY SSF55129 5 154 3.01E-47 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 Gene3D G3DSA:3.30.1390.20 5 142 1.0E-55 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 154 81.434 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 154 1.4E-64 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 Pfam PF00327 Ribosomal protein L30p/L7e 7 54 9.1E-14 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TSIB_0310 8c385274518a1d0e348bf1e9304a5c08 154 Gene3D G3DSA:1.10.15.30 60 114 1.0E-55 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type TSIB_1317 3e082aa14b9c964f181ccdbae6814f80 204 Gene3D G3DSA:1.10.1760.20 1 197 1.0E-63 T 23-10-2018 TSIB_1317 3e082aa14b9c964f181ccdbae6814f80 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 198 5.4E-62 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 TSIB_1716 d5f1851c16e28e4f9aea1bc4992a1c25 285 Pfam PF03239 Iron permease FTR1 family 3 263 1.8E-63 T 23-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 TSIB_1738 df474aed113b53dfe1885deeaaebda21 103 Gene3D G3DSA:2.60.120.10 3 103 2.9E-23 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_1738 df474aed113b53dfe1885deeaaebda21 103 SUPERFAMILY SSF51182 1 100 1.62E-22 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_1738 df474aed113b53dfe1885deeaaebda21 103 Pfam PF07883 Cupin domain 33 100 7.4E-15 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_1879 4728503f6a9400a25e5aa3b05a561894 272 SUPERFAMILY SSF51658 4 243 3.54E-31 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TSIB_1879 4728503f6a9400a25e5aa3b05a561894 272 Pfam PF01261 Xylose isomerase-like TIM barrel 56 216 4.7E-20 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSIB_1879 4728503f6a9400a25e5aa3b05a561894 272 Gene3D G3DSA:3.20.20.150 1 257 2.6E-37 T 23-10-2018 TSIB_0726 856786b3c3af723b39a5542154515102 350 Gene3D G3DSA:3.40.50.1970 3 159 1.2E-34 T 23-10-2018 TSIB_0726 856786b3c3af723b39a5542154515102 350 Pfam PF13685 Iron-containing alcohol dehydrogenase 17 272 2.6E-74 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TSIB_0726 856786b3c3af723b39a5542154515102 350 SUPERFAMILY SSF56796 3 343 1.26E-70 T 23-10-2018 TSIB_0726 856786b3c3af723b39a5542154515102 350 Gene3D G3DSA:1.20.1090.10 160 349 3.3E-64 T 23-10-2018 TSIB_0726 856786b3c3af723b39a5542154515102 350 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 350 46.474 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TSIB_0726 856786b3c3af723b39a5542154515102 350 PIRSF PIRSF000112 3 347 2.3E-68 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TSIB_0466 9f954ac21220906ee04cc4892a827225 217 SUPERFAMILY SSF48613 4 213 3.41E-59 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSIB_0466 9f954ac21220906ee04cc4892a827225 217 Pfam PF03070 TENA/THI-4/PQQC family 9 211 9.7E-48 T 23-10-2018 IPR004305 Thiaminase-2/PQQC TSIB_0466 9f954ac21220906ee04cc4892a827225 217 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 211 7.8E-43 T 23-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 TSIB_0466 9f954ac21220906ee04cc4892a827225 217 Gene3D G3DSA:1.20.910.10 1 215 2.7E-58 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSIB_1718 db6a5d8c8aaeec21b017e414baede704 188 SUPERFAMILY SSF52218 1 168 3.63E-32 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_1718 db6a5d8c8aaeec21b017e414baede704 188 Pfam PF03358 NADPH-dependent FMN reductase 1 135 1.5E-27 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSIB_1718 db6a5d8c8aaeec21b017e414baede704 188 Gene3D G3DSA:3.40.50.360 1 188 4.5E-39 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TSIB_0759 953055d66b75bf4ca589dd47177747a0 76 Pfam PF04024 PspC domain 3 61 4.9E-24 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TSIB_0269 9f88e4fad9765e9e74b5a7b417dc8982 347 Pfam PF01901 Putative O-antigen polymerase 39 317 2.6E-20 T 23-10-2018 IPR002760 Putative O-antigen polymerase TSIB_1073 dfc6cf7a0f457b92aac49efdf43db77f 312 SUPERFAMILY SSF53686 11 302 6.02E-62 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSIB_1073 dfc6cf7a0f457b92aac49efdf43db77f 312 PIRSF PIRSF006278 14 309 1.6E-8 T 23-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase TSIB_1073 dfc6cf7a0f457b92aac49efdf43db77f 312 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 301 9.5E-54 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSIB_1073 dfc6cf7a0f457b92aac49efdf43db77f 312 Gene3D G3DSA:3.40.50.1100 7 305 8.0E-57 T 23-10-2018 TSIB_1073 dfc6cf7a0f457b92aac49efdf43db77f 312 Gene3D G3DSA:3.40.50.1100 43 139 8.0E-57 T 23-10-2018 TSIB_0503 250c902e044466556308f86bb7c7ddd3 79 Gene3D G3DSA:1.10.10.10 1 57 6.7E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0503 250c902e044466556308f86bb7c7ddd3 79 Pfam PF09012 FeoC like transcriptional regulator 18 60 2.2E-5 T 23-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC TSIB_0503 250c902e044466556308f86bb7c7ddd3 79 SUPERFAMILY SSF46785 6 67 5.46E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0451 b6c1f0a5456c17f720a3341e331fa00a 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 9.9E-72 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSIB_0451 b6c1f0a5456c17f720a3341e331fa00a 380 Gene3D G3DSA:1.20.1530.20 1 380 2.1E-100 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 SUPERFAMILY SSF55920 139 314 1.96E-34 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 Gene3D G3DSA:3.40.350.10 8 141 9.3E-22 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 Gene3D G3DSA:3.90.230.10 142 319 5.3E-34 T 23-10-2018 TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 Pfam PF00557 Metallopeptidase family M24 150 309 1.8E-24 T 23-10-2018 IPR000994 Peptidase M24 TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 3.5E-13 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSIB_1737 cafd02fd4c9c1d5c0b7f985281a41d82 384 SUPERFAMILY SSF53092 7 141 1.27E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSIB_0559 ded7837174db76b4224c97298c282073 438 Pfam PF09376 NurA domain 60 406 9.4E-19 T 23-10-2018 IPR018977 NurA domain TSIB_0559 ded7837174db76b4224c97298c282073 438 SMART SM00933 59 406 1.4E-18 T 23-10-2018 IPR018977 NurA domain TSIB_1289 0a0ea7b09f75b9d9d88a0b3edcac16f0 121 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 11 117 1.4E-29 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSIB_1669 2fc26c602bfe564acbcdfb52366cc6cf 328 Pfam PF01594 AI-2E family transporter 11 322 1.1E-39 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TSIB_1256 fe8c707486eaa4deb4eab3076eea828b 251 Pfam PF02361 Cobalt transport protein 10 210 1.8E-28 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TSIB_1053 c776c196fb84c46456d32525e442dec7 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 338 8.2E-48 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_1053 c776c196fb84c46456d32525e442dec7 339 Gene3D G3DSA:1.10.3720.10 94 334 1.2E-15 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1053 c776c196fb84c46456d32525e442dec7 339 SUPERFAMILY SSF161098 101 321 3.4E-8 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0270 6e1e43e1e9bfe2f0c743af3db9cd9c29 814 SUPERFAMILY SSF48239 557 760 8.37E-17 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_0270 6e1e43e1e9bfe2f0c743af3db9cd9c29 814 Gene3D G3DSA:1.50.10.20 535 763 8.2E-14 T 23-10-2018 TSIB_0270 6e1e43e1e9bfe2f0c743af3db9cd9c29 814 Gene3D G3DSA:3.40.50.12610 377 500 3.5E-8 T 23-10-2018 TSIB_0270 6e1e43e1e9bfe2f0c743af3db9cd9c29 814 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 68 215 3.0E-10 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TSIB_1000 92243d9ce70cd1a58f29d7ce00bc7291 229 SUPERFAMILY SSF81301 78 228 3.17E-23 T 23-10-2018 TSIB_1000 92243d9ce70cd1a58f29d7ce00bc7291 229 Gene3D G3DSA:3.30.460.40 73 229 1.0E-31 T 23-10-2018 TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 SMART SM00490 290 374 5.0E-20 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 Gene3D G3DSA:3.40.50.300 25 238 5.4E-39 T 23-10-2018 TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 Pfam PF00271 Helicase conserved C-terminal domain 266 373 5.9E-20 T 23-10-2018 IPR001650 Helicase, C-terminal TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 SUPERFAMILY SSF52540 55 376 2.47E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 SMART SM00487 42 251 1.2E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 Gene3D G3DSA:3.40.50.300 249 472 1.4E-25 T 23-10-2018 TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 Pfam PF00270 DEAD/DEAH box helicase 48 225 1.2E-21 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSIB_0671 b111a1fbbe62b9575be2abf1b1172f52 894 Pfam PF09369 Domain of unknown function (DUF1998) 785 867 9.2E-15 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TSIB_1850 3c44dff3d96643cdff4cac8410b501fc 65 Gene3D G3DSA:3.30.429.10 5 64 9.3E-20 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily TSIB_1850 3c44dff3d96643cdff4cac8410b501fc 65 SUPERFAMILY SSF55331 4 58 9.58E-10 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily TSIB_1850 3c44dff3d96643cdff4cac8410b501fc 65 Pfam PF01361 Tautomerase enzyme 8 58 8.7E-10 T 23-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 SUPERFAMILY SSF55154 1 163 4.91E-41 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 164 9.4E-34 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 SMART SM01118 1 165 3.1E-10 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 Gene3D G3DSA:2.40.320.10 1 170 9.8E-51 T 23-10-2018 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 Pfam PF01928 CYTH domain 2 159 5.7E-26 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSIB_0508 236c9119024452e34cb35792dfbe63e3 172 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 140 5.0E-38 T 23-10-2018 TSIB_1234 71c50d08025935de07b863ff9dd4a0a5 631 SUPERFAMILY SSF54211 42 227 9.86E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1234 71c50d08025935de07b863ff9dd4a0a5 631 Gene3D G3DSA:3.30.230.10 30 224 1.7E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1234 71c50d08025935de07b863ff9dd4a0a5 631 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 57 180 1.7E-14 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSIB_1094 61be9cc593fc53d2849b6b36297bb617 218 PIRSF PIRSF015877 16 215 9.6E-64 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing TSIB_1094 61be9cc593fc53d2849b6b36297bb617 218 SUPERFAMILY SSF75689 21 55 1.96E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_1094 61be9cc593fc53d2849b6b36297bb617 218 Pfam PF01873 Domain found in IF2B/IF5 18 51 3.4E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TSIB_0901 acfb0c1e8e380c3767fac80663324ab0 403 Gene3D G3DSA:3.10.620.30 92 236 4.1E-8 T 23-10-2018 TSIB_0901 acfb0c1e8e380c3767fac80663324ab0 403 Pfam PF04473 Transglutaminase-like domain 106 260 4.7E-44 T 23-10-2018 IPR007562 Transglutaminase-like domain TSIB_1472 8f32d70ac30700046cc50d2aea08b7e9 112 Pfam PF12838 4Fe-4S dicluster domain 56 104 3.2E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSIB_1472 8f32d70ac30700046cc50d2aea08b7e9 112 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1472 8f32d70ac30700046cc50d2aea08b7e9 112 SUPERFAMILY SSF54862 47 110 1.96E-15 T 23-10-2018 TSIB_1472 8f32d70ac30700046cc50d2aea08b7e9 112 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSIB_1472 8f32d70ac30700046cc50d2aea08b7e9 112 Gene3D G3DSA:3.30.70.20 13 112 3.5E-16 T 23-10-2018 TSIB_1692 f62bf4b405246282f68f74a4801dcce3 316 Pfam PF01458 Uncharacterized protein family (UPF0051) 95 312 2.7E-32 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSIB_1692 f62bf4b405246282f68f74a4801dcce3 316 SUPERFAMILY SSF101960 64 314 3.14E-44 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 TIGRFAM TIGR00191 thrB: homoserine kinase 1 279 3.7E-67 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 SUPERFAMILY SSF54211 1 144 9.87E-27 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 Pfam PF00288 GHMP kinases N terminal domain 75 140 3.0E-13 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 SUPERFAMILY SSF55060 158 274 5.04E-31 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 Pfam PF08544 GHMP kinases C terminal 200 266 5.8E-14 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PRINTS PR00958 Homoserine kinase signature 88 103 1.5E-29 T 23-10-2018 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PRINTS PR00958 Homoserine kinase signature 163 180 1.5E-29 T 23-10-2018 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PRINTS PR00958 Homoserine kinase signature 127 140 1.5E-29 T 23-10-2018 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PRINTS PR00958 Homoserine kinase signature 8 23 1.5E-29 T 23-10-2018 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PRINTS PR00958 Homoserine kinase signature 242 257 1.5E-29 T 23-10-2018 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 PIRSF PIRSF000676 1 291 4.9E-81 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 Gene3D G3DSA:3.30.70.890 160 285 8.2E-38 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 Gene3D G3DSA:3.30.230.10 1 159 1.9E-40 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSIB_1601 586bc9cd37335f5eab8c92bc1e054846 291 Hamap MF_00384 Homoserine kinase [thrB]. 3 285 28.812 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSIB_1425 cff7fec17998bab39255c7b9859efe5f 79 Gene3D G3DSA:3.30.70.920 1 74 1.1E-22 T 23-10-2018 TSIB_1425 cff7fec17998bab39255c7b9859efe5f 79 SUPERFAMILY SSF54909 2 75 1.74E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TSIB_1425 cff7fec17998bab39255c7b9859efe5f 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 8.8E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSIB_1691 b959686f730b4a6349482ec7224625f5 133 Gene3D G3DSA:3.30.420.130 1 104 5.1E-34 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_1691 b959686f730b4a6349482ec7224625f5 133 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 8.5E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSIB_1691 b959686f730b4a6349482ec7224625f5 133 SUPERFAMILY SSF53146 1 108 2.09E-32 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSIB_0536 db76884a55c40467e5b05ecccec7b2aa 416 Gene3D G3DSA:3.60.60.10 2 293 6.3E-24 T 23-10-2018 TSIB_0536 db76884a55c40467e5b05ecccec7b2aa 416 Pfam PF03577 Peptidase family C69 74 191 9.8E-11 T 23-10-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 TSIB_0016 cdedb8406b0d7210c7c577b43a42b217 125 Gene3D G3DSA:1.20.120.330 5 125 1.0E-22 T 23-10-2018 TSIB_0016 cdedb8406b0d7210c7c577b43a42b217 125 SUPERFAMILY SSF81593 14 124 4.32E-10 T 23-10-2018 TSIB_0016 cdedb8406b0d7210c7c577b43a42b217 125 Pfam PF05168 HEPN domain 10 123 6.2E-22 T 23-10-2018 IPR007842 HEPN domain TSIB_0613 e389e6b5088c04bab3955c55d336fefa 252 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 2.2E-18 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSIB_0613 e389e6b5088c04bab3955c55d336fefa 252 Gene3D G3DSA:3.40.50.300 3 241 3.5E-43 T 23-10-2018 TSIB_0613 e389e6b5088c04bab3955c55d336fefa 252 SUPERFAMILY SSF52540 1 246 4.4E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0572 c16f254d32e97f57c3cf53a90617355b 195 Pfam PF03956 Lysine exporter LysO 9 191 5.7E-59 T 23-10-2018 IPR005642 Lysine exporter LysO TSIB_0572 c16f254d32e97f57c3cf53a90617355b 195 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 194 4.0E-50 T 23-10-2018 IPR005642 Lysine exporter LysO TSIB_1574 45468243fa5353f2b19966da55b289db 354 Pfam PF01168 Alanine racemase, N-terminal domain 7 221 1.5E-19 T 23-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSIB_1574 45468243fa5353f2b19966da55b289db 354 SUPERFAMILY SSF51419 7 231 3.4E-28 T 23-10-2018 IPR029066 PLP-binding barrel TSIB_1574 45468243fa5353f2b19966da55b289db 354 Gene3D G3DSA:3.20.20.10 9 221 3.9E-25 T 23-10-2018 IPR029066 PLP-binding barrel TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 145 158 1.4E-17 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 1.4E-17 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 253 267 1.4E-17 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 131 144 1.4E-17 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 SUPERFAMILY SSF53474 34 309 4.96E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 Gene3D G3DSA:3.40.50.1820 29 309 2.0E-62 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 Pfam PF00561 alpha/beta hydrolase fold 59 296 1.2E-23 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00412 Epoxide hydrolase signature 251 267 4.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00412 Epoxide hydrolase signature 284 306 4.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00412 Epoxide hydrolase signature 145 158 4.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSIB_1454 eca53d6e42d51043c7469d8e1181b168 309 PRINTS PR00412 Epoxide hydrolase signature 63 81 4.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSIB_1967 1d2f886f2516d89455bc7840966dadff 83 Gene3D G3DSA:3.30.70.1340 1 68 7.7E-25 T 23-10-2018 IPR023129 MTH889-like domain superfamily TSIB_1967 1d2f886f2516d89455bc7840966dadff 83 Pfam PF02680 Uncharacterized ArCR, COG1888 2 73 5.2E-29 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TSIB_1967 1d2f886f2516d89455bc7840966dadff 83 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 1 77 7.0E-34 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TSIB_1967 1d2f886f2516d89455bc7840966dadff 83 SUPERFAMILY SSF160363 3 75 2.75E-26 T 23-10-2018 IPR023129 MTH889-like domain superfamily TSIB_0201 26b789be5cc4b596b75341e608f3e39e 260 SUPERFAMILY SSF56281 10 260 4.19E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0201 26b789be5cc4b596b75341e608f3e39e 260 Gene3D G3DSA:3.60.15.10 8 260 1.8E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_0201 26b789be5cc4b596b75341e608f3e39e 260 Pfam PF12706 Beta-lactamase superfamily domain 56 231 5.2E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_0201 26b789be5cc4b596b75341e608f3e39e 260 SMART SM00849 45 233 2.5E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1008 932bf8477676d31fa83580d403754800 82 SUPERFAMILY SSF54285 2 82 1.89E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSIB_1008 932bf8477676d31fa83580d403754800 82 Pfam PF02597 ThiS family 4 82 3.1E-21 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSIB_1008 932bf8477676d31fa83580d403754800 82 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 82 5.4E-25 T 23-10-2018 IPR010038 MoaD, archaeal-type TSIB_1008 932bf8477676d31fa83580d403754800 82 Gene3D G3DSA:3.10.20.30 1 82 2.0E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TSIB_1767 1d091484d1e7526be45e2838531c3c70 397 Gene3D G3DSA:2.20.20.80 108 170 1.0E-48 T 23-10-2018 TSIB_1767 1d091484d1e7526be45e2838531c3c70 397 SUPERFAMILY SSF140914 2 249 3.14E-24 T 23-10-2018 TSIB_1767 1d091484d1e7526be45e2838531c3c70 397 Gene3D G3DSA:1.20.930.50 8 225 1.0E-48 T 23-10-2018 TSIB_1767 1d091484d1e7526be45e2838531c3c70 397 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 142 361 1.6E-31 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TSIB_1767 1d091484d1e7526be45e2838531c3c70 397 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 388 27.883 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 TSIB_1709 b80dc39ef24bd120b7838602b814a1fe 203 SUPERFAMILY SSF53335 8 198 6.75E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1709 b80dc39ef24bd120b7838602b814a1fe 203 Gene3D G3DSA:3.40.50.150 13 203 4.7E-42 T 23-10-2018 TSIB_1709 b80dc39ef24bd120b7838602b814a1fe 203 Pfam PF08241 Methyltransferase domain 45 140 1.2E-23 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSIB_0006 47ba7708ad541fefd0a7d41efbe57612 290 Pfam PF00535 Glycosyl transferase family 2 5 119 3.5E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_0006 47ba7708ad541fefd0a7d41efbe57612 290 Gene3D G3DSA:3.90.550.10 2 223 3.8E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0006 47ba7708ad541fefd0a7d41efbe57612 290 SUPERFAMILY SSF53448 1 242 3.87E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2059 c1e262c4359a96e919e0abadcb8211e7 330 SUPERFAMILY SSF53448 4 319 2.68E-50 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_2059 c1e262c4359a96e919e0abadcb8211e7 330 Pfam PF00535 Glycosyl transferase family 2 7 62 4.3E-10 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_2059 c1e262c4359a96e919e0abadcb8211e7 330 Pfam PF00535 Glycosyl transferase family 2 100 181 4.9E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_1604 368f04b88b4558d522b8a60ca829c92c 109 SUPERFAMILY SSF52518 43 86 1.88E-8 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1604 368f04b88b4558d522b8a60ca829c92c 109 Gene3D G3DSA:3.40.50.970 9 102 4.8E-11 T 23-10-2018 TSIB_0822 b87b12b08065252661b198cbfdac17e8 438 Gene3D G3DSA:1.10.4160.10 10 434 4.4E-40 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily TSIB_0822 b87b12b08065252661b198cbfdac17e8 438 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 19 396 2.0E-15 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 TSIB_0104 81c384f7390b7044dac733ba6710e666 290 Pfam PF05763 Protein of unknown function (DUF835) 131 256 8.3E-37 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_1943 386645b15eb00569b9a8963fe3689fc2 130 Gene3D G3DSA:3.50.30.10 1 130 6.0E-50 T 23-10-2018 TSIB_1943 386645b15eb00569b9a8963fe3689fc2 130 Pfam PF01989 Protein of unknown function DUF126 24 103 1.3E-35 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative TSIB_1943 386645b15eb00569b9a8963fe3689fc2 130 Hamap MF_00078 UPF0107 protein . 2 129 33.015 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative TSIB_1943 386645b15eb00569b9a8963fe3689fc2 130 SUPERFAMILY SSF52016 1 127 4.79E-43 T 23-10-2018 TSIB_1943 386645b15eb00569b9a8963fe3689fc2 130 PIRSF PIRSF004966 1 130 1.6E-52 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 Pfam PF02254 TrkA-N domain 134 241 8.1E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 SUPERFAMILY SSF81324 16 131 1.44E-28 T 23-10-2018 TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 Gene3D G3DSA:3.40.50.720 112 255 2.6E-28 T 23-10-2018 TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 Gene3D G3DSA:1.10.287.70 4 102 1.6E-21 T 23-10-2018 TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 SUPERFAMILY SSF51735 116 264 1.22E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TSIB_1993 c0d5c167d5673ec7c55892ff90a0fb27 333 Pfam PF07885 Ion channel 30 100 3.1E-16 T 23-10-2018 IPR013099 Potassium channel domain TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 SUPERFAMILY SSF52922 192 327 2.49E-40 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 Pfam PF02779 Transketolase, pyrimidine binding domain 6 182 8.6E-54 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 Gene3D G3DSA:3.40.50.920 196 327 3.7E-47 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 SMART SM00861 7 183 3.3E-70 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 Gene3D G3DSA:3.40.50.970 4 195 4.1E-89 T 23-10-2018 TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 SUPERFAMILY SSF52518 6 207 3.21E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TSIB_1638 1755f1ba6457fd99655cd98683ec3c80 327 Pfam PF02780 Transketolase, C-terminal domain 197 319 4.7E-41 T 23-10-2018 IPR033248 Transketolase, C-terminal domain TSIB_0874 f2482a642f899307c7487f44ecf939f6 90 Pfam PF11491 Protein of unknown function (DUF3213) 5 87 4.0E-38 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 TSIB_0874 f2482a642f899307c7487f44ecf939f6 90 Gene3D G3DSA:3.30.70.1750 2 90 1.9E-29 T 23-10-2018 TSIB_1025 2a360bea6ebd8c81c3064ec465893ab8 138 Pfam PF01877 RNA binding 7 116 1.4E-16 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TSIB_1025 2a360bea6ebd8c81c3064ec465893ab8 138 SUPERFAMILY SSF55282 7 137 2.88E-37 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1025 2a360bea6ebd8c81c3064ec465893ab8 138 Gene3D G3DSA:3.30.1440.10 1 137 3.4E-44 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_1025 2a360bea6ebd8c81c3064ec465893ab8 138 Hamap MF_01112 UPF0201 protein . 6 135 24.372 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TSIB_1329 702b8302f27cfdfa7ec4804b3ea9e301 136 SUPERFAMILY SSF143870 14 125 2.22E-21 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TSIB_1329 702b8302f27cfdfa7ec4804b3ea9e301 136 Gene3D G3DSA:3.30.2380.10 5 136 1.2E-45 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TSIB_1329 702b8302f27cfdfa7ec4804b3ea9e301 136 Pfam PF08617 Kinase binding protein CGI-121 37 119 1.6E-6 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 TSIB_0860 f6807f7951acaaf453c4c187113c371a 341 Gene3D G3DSA:1.10.10.10 259 333 1.1E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0860 f6807f7951acaaf453c4c187113c371a 341 SUPERFAMILY SSF46785 273 335 4.1E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0860 f6807f7951acaaf453c4c187113c371a 341 Pfam PF01047 MarR family 284 324 1.4E-5 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSIB_1047 7e3c42c667ffc12a873515f86c681a16 225 SUPERFAMILY SSF56112 23 163 6.53E-12 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TSIB_1047 7e3c42c667ffc12a873515f86c681a16 225 Gene3D G3DSA:3.30.200.20 29 105 1.6E-5 T 23-10-2018 TSIB_0784 bc848c939ac611e44460c7cca21b7ed9 274 Pfam PF04659 Archaeal flagella protein 154 246 1.0E-27 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TSIB_0784 bc848c939ac611e44460c7cca21b7ed9 274 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 157 258 2.0E-38 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TSIB_0784 bc848c939ac611e44460c7cca21b7ed9 274 PIRSF PIRSF017066 74 274 5.4E-58 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal TSIB_0784 bc848c939ac611e44460c7cca21b7ed9 274 PIRSF PIRSF017066 1 97 8.2E-17 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Gene3D G3DSA:3.30.310.50 372 456 1.7E-31 T 23-10-2018 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 448 4.4E-174 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 SUPERFAMILY SSF53738 3 181 1.06E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 370 6.8E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 257 2.7E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 SUPERFAMILY SSF53738 157 260 9.03E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 SUPERFAMILY SSF55957 359 456 7.46E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 139 4.0E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 2.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 2.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 2.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 SUPERFAMILY SSF53738 262 368 2.08E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Gene3D G3DSA:3.40.120.10 170 359 2.1E-75 T 23-10-2018 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 384 443 3.6E-14 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Gene3D G3DSA:3.40.120.10 258 365 2.1E-75 T 23-10-2018 TSIB_0248 da1623ed20daa9d2bb320d2833a379d8 457 Gene3D G3DSA:3.40.120.10 1 153 1.9E-58 T 23-10-2018 TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 SMART SM00788 3 334 1.1E-161 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 Gene3D G3DSA:3.40.440.10 1 339 1.0E-137 T 23-10-2018 TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 Pfam PF00709 Adenylosuccinate synthetase 150 290 1.9E-43 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 SUPERFAMILY SSF52540 1 335 2.23E-108 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0650 00911554f83c350d0890aac9ba8d9cd2 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 100.448 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 SUPERFAMILY SSF52540 243 495 2.51E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 SMART SM00382 32 221 4.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 Gene3D G3DSA:3.40.50.300 256 501 3.7E-43 T 23-10-2018 TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 SUPERFAMILY SSF52540 5 231 5.54E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 Pfam PF00005 ABC transporter 23 173 1.2E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 Pfam PF00005 ABC transporter 278 434 2.5E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSIB_0181 8a544538c6527d964585db27e69c3a7f 509 Gene3D G3DSA:3.40.50.300 4 242 4.6E-56 T 23-10-2018 TSIB_0364 6aea0e3996a2286665719cf1e0d41893 494 SUPERFAMILY SSF53743 49 331 1.44E-50 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 TSIB_0364 6aea0e3996a2286665719cf1e0d41893 494 Pfam PF02952 L-fucose isomerase, C-terminal domain 349 479 2.0E-26 T 23-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 TSIB_1221 b2955b430e0eb3b31f7eae42967f790f 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 215 2.0E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSIB_1221 b2955b430e0eb3b31f7eae42967f790f 237 PIRSF PIRSF015736 1 237 2.1E-88 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TSIB_1221 b2955b430e0eb3b31f7eae42967f790f 237 Gene3D G3DSA:3.40.50.12500 6 237 4.8E-88 T 23-10-2018 TSIB_1898 bb49c7b44257816a8168cc9011fb0ad0 179 Gene3D G3DSA:1.20.1260.10 6 149 2.4E-24 T 23-10-2018 IPR012347 Ferritin-like TSIB_1898 bb49c7b44257816a8168cc9011fb0ad0 179 SUPERFAMILY SSF47240 12 144 2.03E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1898 bb49c7b44257816a8168cc9011fb0ad0 179 Pfam PF02915 Rubrerythrin 16 143 3.1E-20 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_0153 f51c1731da4f4bc95e03be0bc213118f 278 Gene3D G3DSA:1.10.357.20 101 278 6.4E-14 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TSIB_0153 f51c1731da4f4bc95e03be0bc213118f 278 Pfam PF01769 Divalent cation transporter 10 67 1.8E-8 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TSIB_0153 f51c1731da4f4bc95e03be0bc213118f 278 Pfam PF01769 Divalent cation transporter 146 271 2.0E-19 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TSIB_0153 f51c1731da4f4bc95e03be0bc213118f 278 SUPERFAMILY SSF161093 11 72 2.48E-10 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TSIB_0153 f51c1731da4f4bc95e03be0bc213118f 278 SUPERFAMILY SSF161093 105 277 5.62E-28 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TSIB_1951 9ddf156b724386da7eded6660c59d60f 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 2 163 1.0E-45 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TSIB_1951 9ddf156b724386da7eded6660c59d60f 164 Gene3D G3DSA:2.40.50.100 97 163 1.7E-26 T 23-10-2018 TSIB_1951 9ddf156b724386da7eded6660c59d60f 164 PIRSF PIRSF019115 1 164 1.2E-63 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TSIB_1445 964e746efa7fa8945da81c2735b1611d 87 Hamap MF_01245 UPF0248 protein . 10 79 18.363 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TSIB_1445 964e746efa7fa8945da81c2735b1611d 87 Pfam PF04457 Protein of unknown function (DUF504) 26 78 2.3E-14 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TSIB_1940 f499a28bc9ef37cb3258aabd380e1f64 142 Pfam PF04021 Class III signal peptide 11 37 1.4E-9 T 23-10-2018 IPR007166 Class III signal peptide motif TSIB_0652 a35751adc2fda46adc72e4222b2927a0 61 Pfam PF12146 Serine aminopeptidase, S33 10 57 1.2E-17 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 TSIB_0652 a35751adc2fda46adc72e4222b2927a0 61 Gene3D G3DSA:3.40.50.1820 2 61 1.7E-15 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_0652 a35751adc2fda46adc72e4222b2927a0 61 SUPERFAMILY SSF53474 6 53 6.36E-16 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TSIB_1337 a5adc5b0bf8c47322e8efca11c3aba7f 356 Gene3D G3DSA:1.25.40.10 1 352 5.8E-55 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0571 b39eecec06b2aea388591432964b4c73 79 Pfam PF03956 Lysine exporter LysO 6 75 3.0E-6 T 23-10-2018 IPR005642 Lysine exporter LysO TSIB_1153 378c479e929f8d4386cf8437a015ed8a 403 SUPERFAMILY SSF52540 58 306 5.02E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1153 378c479e929f8d4386cf8437a015ed8a 403 Gene3D G3DSA:3.40.50.300 51 239 2.0E-8 T 23-10-2018 TSIB_1823 db8de0a7778796ec49d9404fa34cec39 351 SUPERFAMILY SSF53448 1 226 2.66E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_1823 db8de0a7778796ec49d9404fa34cec39 351 Pfam PF00535 Glycosyl transferase family 2 3 168 6.6E-37 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSIB_1823 db8de0a7778796ec49d9404fa34cec39 351 Pfam PF04138 GtrA-like protein 235 350 5.5E-24 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TSIB_1823 db8de0a7778796ec49d9404fa34cec39 351 Gene3D G3DSA:3.90.550.10 1 239 8.0E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSIB_0429 33d5f3a5694e8dad812090c1f4bd5e23 251 SUPERFAMILY SSF55307 159 244 8.24E-12 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TSIB_0429 33d5f3a5694e8dad812090c1f4bd5e23 251 Gene3D G3DSA:3.40.50.1440 114 249 1.3E-7 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSIB_1922 6ce58bb7528ad7ac91485de617637018 365 Pfam PF04007 Protein of unknown function (DUF354) 5 325 1.0E-88 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TSIB_1922 6ce58bb7528ad7ac91485de617637018 365 SUPERFAMILY SSF53756 5 322 1.08E-22 T 23-10-2018 TSIB_1922 6ce58bb7528ad7ac91485de617637018 365 PIRSF PIRSF005357 4 350 7.4E-118 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TSIB_0425 a669b1d458df0178560ce438f94d9252 70 Gene3D G3DSA:1.10.10.10 1 66 5.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSIB_0425 a669b1d458df0178560ce438f94d9252 70 SUPERFAMILY SSF46785 5 52 8.61E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0517 2dfdbc14fd10fb37aeaa19c35f3cb78e 176 Pfam PF01613 Flavin reductase like domain 8 138 2.5E-20 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSIB_0517 2dfdbc14fd10fb37aeaa19c35f3cb78e 176 SMART SM00903 5 154 4.4E-10 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSIB_0517 2dfdbc14fd10fb37aeaa19c35f3cb78e 176 Gene3D G3DSA:2.30.110.10 2 174 8.2E-42 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSIB_0517 2dfdbc14fd10fb37aeaa19c35f3cb78e 176 SUPERFAMILY SSF50475 4 151 1.03E-33 T 23-10-2018 TSIB_1328 85fc16a87e94913c745c750b1e168ef7 398 Pfam PF00155 Aminotransferase class I and II 40 390 2.3E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1328 85fc16a87e94913c745c750b1e168ef7 398 Gene3D G3DSA:3.90.1150.10 37 391 5.5E-134 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1328 85fc16a87e94913c745c750b1e168ef7 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSIB_1328 85fc16a87e94913c745c750b1e168ef7 398 Gene3D G3DSA:3.40.640.10 72 291 5.5E-134 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_1328 85fc16a87e94913c745c750b1e168ef7 398 SUPERFAMILY SSF53383 16 397 1.84E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1183 78121ec39ce8a5e9082895a8f85807e0 279 Gene3D G3DSA:3.40.50.150 119 278 3.7E-23 T 23-10-2018 TSIB_1183 78121ec39ce8a5e9082895a8f85807e0 279 SUPERFAMILY SSF53335 90 265 3.83E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1183 78121ec39ce8a5e9082895a8f85807e0 279 Pfam PF13649 Methyltransferase domain 130 231 3.5E-9 T 23-10-2018 TSIB_1948 c4a5affa4b89c077a3d2d65c47b17fc7 415 Gene3D G3DSA:3.60.21.10 240 406 2.8E-45 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_1948 c4a5affa4b89c077a3d2d65c47b17fc7 415 Pfam PF13563 2'-5' RNA ligase superfamily 41 182 3.1E-14 T 23-10-2018 TSIB_1948 c4a5affa4b89c077a3d2d65c47b17fc7 415 SUPERFAMILY SSF56300 242 391 7.75E-15 T 23-10-2018 TSIB_1948 c4a5affa4b89c077a3d2d65c47b17fc7 415 SUPERFAMILY SSF55144 22 181 7.85E-10 T 23-10-2018 IPR009097 Cyclic phosphodiesterase TSIB_1948 c4a5affa4b89c077a3d2d65c47b17fc7 415 Gene3D G3DSA:3.90.1140.10 23 204 1.1E-13 T 23-10-2018 TSIB_1720 69151e4d0f6b157bed8a507e2c19b8cc 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 4.4E-62 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSIB_1720 69151e4d0f6b157bed8a507e2c19b8cc 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 29 464 2.4E-189 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TSIB_1720 69151e4d0f6b157bed8a507e2c19b8cc 475 SUPERFAMILY SSF101960 39 468 8.37E-124 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSIB_1798 a76baf9192527c76ac6e2e0240b067ff 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 8.3E-15 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H TSIB_1988 6d1c29e906b306998c5ec229ea276ade 608 Pfam PF05124 S-layer like family, C-terminal region 519 582 2.7E-11 T 23-10-2018 IPR022651 S-layer protein, C-terminal TSIB_1988 6d1c29e906b306998c5ec229ea276ade 608 SUPERFAMILY SSF51126 31 227 9.42E-6 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor TSIB_0043 1fa5783684b375274e01b9adbd2ef230 258 Pfam PF09874 Predicted membrane protein (DUF2101) 25 232 5.0E-73 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane TSIB_1203 d459093f7638d8bdb05279489ca33200 374 Pfam PF13699 Domain of unknown function (DUF4157) 124 160 8.4E-6 T 23-10-2018 IPR025295 Domain of unknown function DUF4157 TSIB_1944 014a7393d0e0a95d10f3b11f3caffaac 386 Pfam PF04412 Protein of unknown function (DUF521) 1 382 2.5E-147 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative TSIB_0614 a60812f92193d13453f36c48238691b7 82 SUPERFAMILY SSF50249 23 81 2.51E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_0614 a60812f92193d13453f36c48238691b7 82 Gene3D G3DSA:2.40.50.140 14 81 7.3E-27 T 23-10-2018 TSIB_0614 a60812f92193d13453f36c48238691b7 82 Pfam PF01938 TRAM domain 25 81 5.6E-15 T 23-10-2018 IPR002792 TRAM domain TSIB_0223 3c935537cc7015338da20b23a7886090 380 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 379 1.3E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TSIB_0223 3c935537cc7015338da20b23a7886090 380 SUPERFAMILY SSF52317 87 319 8.24E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1956 c4518c2e46f25d295a8e16de05fc0110 353 Gene3D G3DSA:1.20.81.30 177 286 6.8E-12 T 23-10-2018 TSIB_1956 c4518c2e46f25d295a8e16de05fc0110 353 Pfam PF00482 Type II secretion system (T2SS), protein F 185 309 8.4E-23 T 23-10-2018 IPR018076 Type II secretion system F domain TSIB_2013 9ccdbcc0ed8a286a816fec8dc357c466 429 Pfam PF13173 AAA domain 35 168 9.7E-38 T 23-10-2018 TSIB_2013 9ccdbcc0ed8a286a816fec8dc357c466 429 SUPERFAMILY SSF52540 24 213 7.86E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_2013 9ccdbcc0ed8a286a816fec8dc357c466 429 Gene3D G3DSA:3.40.50.300 18 100 1.1E-5 T 23-10-2018 TSIB_2013 9ccdbcc0ed8a286a816fec8dc357c466 429 Pfam PF13635 Domain of unknown function (DUF4143) 285 372 1.3E-12 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TSIB_1210 964ba448a77da855c6fa8d763f7092d4 258 Gene3D G3DSA:3.40.630.30 1 161 2.2E-8 T 23-10-2018 TSIB_1210 964ba448a77da855c6fa8d763f7092d4 258 SUPERFAMILY SSF55729 1 154 1.93E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSIB_1462 865844c92eba352da38cffe222661c16 230 Pfam PF01909 Nucleotidyltransferase domain 14 90 8.7E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSIB_1462 865844c92eba352da38cffe222661c16 230 Gene3D G3DSA:3.30.460.10 1 94 1.7E-8 T 23-10-2018 TSIB_1462 865844c92eba352da38cffe222661c16 230 SUPERFAMILY SSF81301 22 72 2.07E-7 T 23-10-2018 TSIB_1164 f3e5c3f1697339a625ba0f2fb1b8104e 197 PIRSF PIRSF004897 1 165 1.5E-41 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TSIB_0580 570ae271fd165bf44231de004262a6f5 423 SUPERFAMILY SSF51445 6 414 1.2E-127 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TSIB_0580 570ae271fd165bf44231de004262a6f5 423 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 322 330 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site TSIB_0580 570ae271fd165bf44231de004262a6f5 423 Pfam PF00232 Glycosyl hydrolase family 1 6 409 3.4E-87 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 Gene3D G3DSA:3.20.20.80 4 423 7.6E-147 T 23-10-2018 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 391 5.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 PRINTS PR00131 Glycosyl hydrolase family 1 signature 260 274 5.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 PRINTS PR00131 Glycosyl hydrolase family 1 signature 334 345 5.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 PRINTS PR00131 Glycosyl hydrolase family 1 signature 322 330 5.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_0580 570ae271fd165bf44231de004262a6f5 423 PRINTS PR00131 Glycosyl hydrolase family 1 signature 355 372 5.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSIB_1743 f96e2dce00efeafb449bbaab231c7748 128 Gene3D G3DSA:1.10.260.40 10 63 6.0E-6 T 23-10-2018 TSIB_1743 f96e2dce00efeafb449bbaab231c7748 128 SUPERFAMILY SSF47413 14 53 1.97E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 Gene3D G3DSA:3.40.50.300 1 183 4.6E-37 T 23-10-2018 TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 176 6.6E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 SUPERFAMILY SSF52540 2 182 3.05E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 2.7E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 2.7E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1659 528af2074bd77e3b41198b66b8215e29 188 Pfam PF01926 50S ribosome-binding GTPase 3 136 6.8E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TSIB_1347 1affc71536b594d83f1814faa775fd56 196 Pfam PF02915 Rubrerythrin 25 159 2.3E-22 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1347 1affc71536b594d83f1814faa775fd56 196 SUPERFAMILY SSF47240 16 162 8.31E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_1347 1affc71536b594d83f1814faa775fd56 196 Gene3D G3DSA:1.20.1260.10 15 162 1.5E-34 T 23-10-2018 IPR012347 Ferritin-like TSIB_0816 d4822f2f353d514672b2e2d8f9036719 153 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 8 79 3.0E-12 T 23-10-2018 TSIB_0816 d4822f2f353d514672b2e2d8f9036719 153 Pfam PF01936 NYN domain 8 138 9.1E-12 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TSIB_0816 d4822f2f353d514672b2e2d8f9036719 153 Gene3D G3DSA:3.40.50.1010 3 139 7.3E-10 T 23-10-2018 TSIB_1729 affe52910ff7b66a311d40b6495b563c 67 Pfam PF01361 Tautomerase enzyme 5 60 3.7E-8 T 23-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 TSIB_1729 affe52910ff7b66a311d40b6495b563c 67 SUPERFAMILY SSF55331 14 61 3.82E-8 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily TSIB_1729 affe52910ff7b66a311d40b6495b563c 67 Gene3D G3DSA:3.30.429.10 5 61 2.3E-16 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily TSIB_0582 0b9039cbc20f5977f7c2a3866a4470ce 364 Pfam PF03065 Glycosyl hydrolase family 57 3 314 2.0E-46 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TSIB_0582 0b9039cbc20f5977f7c2a3866a4470ce 364 Gene3D G3DSA:3.20.110.20 3 176 1.5E-25 T 23-10-2018 TSIB_0582 0b9039cbc20f5977f7c2a3866a4470ce 364 SUPERFAMILY SSF88713 3 307 1.18E-39 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSIB_1508 81ef43da1ba77aa49968e10029af9b68 140 Gene3D G3DSA:1.20.120.580 1 139 6.7E-13 T 23-10-2018 IPR037038 Bsu32300-like superfamily TSIB_1508 81ef43da1ba77aa49968e10029af9b68 140 Pfam PF01934 Protein of unknown function DUF86 15 127 2.8E-12 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TSIB_1572 c953217952ee7d58d096e35787d5adc9 120 Pfam PF14330 Domain of unknown function (DUF4387) 6 102 1.4E-36 T 23-10-2018 IPR025496 Protein of unknown function DUF4387 TSIB_1290 7ac92a10c74f9061dca567d0ab00d351 155 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 5 138 3.3E-28 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TSIB_0776 ccdc6370621fcb7667e8fabde401d354 118 Gene3D G3DSA:2.60.120.10 5 106 1.5E-21 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TSIB_0776 ccdc6370621fcb7667e8fabde401d354 118 SUPERFAMILY SSF51182 12 105 1.26E-23 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TSIB_0776 ccdc6370621fcb7667e8fabde401d354 118 Pfam PF07883 Cupin domain 36 104 2.5E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TSIB_0190 53b8acd7822cf6066c445dd39a26e69d 82 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 11 75 3.9E-6 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TSIB_0696 aeba6fa273f04f246240fef25955edb8 213 Gene3D G3DSA:3.40.50.150 2 210 1.5E-62 T 23-10-2018 TSIB_0696 aeba6fa273f04f246240fef25955edb8 213 SUPERFAMILY SSF53335 6 181 6.39E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0696 aeba6fa273f04f246240fef25955edb8 213 Pfam PF08241 Methyltransferase domain 44 128 1.8E-18 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSIB_0668 a6447bd0542e6cb159c23587a373d3b7 347 Pfam PF05763 Protein of unknown function (DUF835) 231 343 9.2E-27 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_1942 a307b78fc0c3a75d3a7762d97a50ce4b 412 Pfam PF02163 Peptidase family M50 300 336 1.5E-6 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSIB_0930 2463c1e0320a575f7a3660059729b24e 250 SUPERFAMILY SSF53335 12 247 9.6E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_0930 2463c1e0320a575f7a3660059729b24e 250 Pfam PF13649 Methyltransferase domain 40 134 1.6E-24 T 23-10-2018 TSIB_0930 2463c1e0320a575f7a3660059729b24e 250 Gene3D G3DSA:3.40.50.150 9 246 1.7E-50 T 23-10-2018 TSIB_0051 7cb6aba6ef570b46c9e68b4447ee01db 271 Pfam PF14378 PAP2 superfamily 63 213 1.9E-9 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 TSIB_0051 7cb6aba6ef570b46c9e68b4447ee01db 271 Gene3D G3DSA:1.20.144.10 142 239 7.5E-7 T 23-10-2018 TSIB_0051 7cb6aba6ef570b46c9e68b4447ee01db 271 SUPERFAMILY SSF48317 65 220 2.07E-9 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSIB_1285 a7781d2cfacc4e8ef1991cc84901680d 186 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 103 159 3.0E-9 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1285 a7781d2cfacc4e8ef1991cc84901680d 186 SUPERFAMILY SSF143243 36 161 8.5E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1285 a7781d2cfacc4e8ef1991cc84901680d 186 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 159 3.4E-19 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1285 a7781d2cfacc4e8ef1991cc84901680d 186 Gene3D G3DSA:3.30.460.80 19 142 4.8E-13 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1999 096f953c6604f94ae43d4cc799cd585c 178 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 42 175 5.6E-42 T 23-10-2018 IPR005247 YbhB/YbcL TSIB_1999 096f953c6604f94ae43d4cc799cd585c 178 SUPERFAMILY SSF49777 28 177 1.44E-42 T 23-10-2018 IPR036610 PEBP-like superfamily TSIB_1999 096f953c6604f94ae43d4cc799cd585c 178 Gene3D G3DSA:3.90.280.10 18 178 3.0E-49 T 23-10-2018 IPR036610 PEBP-like superfamily TSIB_1999 096f953c6604f94ae43d4cc799cd585c 178 Pfam PF01161 Phosphatidylethanolamine-binding protein 38 175 1.1E-31 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein TSIB_0080 7a4799eb52acbe0a2333d2ab06450b87 204 Pfam PF01914 MarC family integral membrane protein 4 195 2.8E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSIB_1309 d29e5d49411a9c095ba77ed0ff4a3a40 169 Pfam PF01899 Na+/H+ ion antiporter subunit 10 166 2.4E-43 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_1309 d29e5d49411a9c095ba77ed0ff4a3a40 169 PIRSF PIRSF019239 3 168 9.6E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_0115 1d7a9f637e92bca47606fcaf13e82fb8 183 Pfam PF04017 Domain of unknown function (DUF366) 2 180 1.7E-64 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TSIB_0115 1d7a9f637e92bca47606fcaf13e82fb8 183 PIRSF PIRSF006503 1 183 9.5E-77 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TSIB_0115 1d7a9f637e92bca47606fcaf13e82fb8 183 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 1 181 1.0E-71 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TSIB_0115 1d7a9f637e92bca47606fcaf13e82fb8 183 SUPERFAMILY SSF55681 2 182 2.49E-69 T 23-10-2018 TSIB_0115 1d7a9f637e92bca47606fcaf13e82fb8 183 Gene3D G3DSA:3.30.930.10 1 183 9.1E-68 T 23-10-2018 TSIB_0825 ea60d241d111436a443d433b2c1f50ad 58 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 1 58 6.0E-24 T 23-10-2018 IPR020199 Uncharacterised protein family PYRAB06030 TSIB_0272 5d5b04ea4ec88182c477509fd462a3cf 318 Pfam PF07282 Putative transposase DNA-binding domain 209 278 3.2E-23 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_0272 5d5b04ea4ec88182c477509fd462a3cf 318 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 155 236 5.9E-22 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSIB_0272 5d5b04ea4ec88182c477509fd462a3cf 318 Pfam PF01385 Probable transposase 75 190 1.1E-25 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TSIB_1655 bd7a4dfac2a7f28dcf8654b0716443a3 213 Gene3D G3DSA:3.40.50.11570 8 212 1.3E-43 T 23-10-2018 TSIB_1655 bd7a4dfac2a7f28dcf8654b0716443a3 213 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 211 2.8E-50 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TSIB_2006 0552d9ed7839b1eab1ef095492738999 422 Gene3D G3DSA:1.20.1530.20 3 395 5.0E-75 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_2006 0552d9ed7839b1eab1ef095492738999 422 Pfam PF00999 Sodium/hydrogen exchanger family 9 384 4.3E-50 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 Pfam PF01545 Cation efflux family 8 200 6.5E-46 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 SUPERFAMILY SSF161111 3 202 1.26E-54 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 Gene3D G3DSA:3.30.70.1350 204 282 2.4E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 Gene3D G3DSA:1.20.1510.10 3 200 3.0E-61 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 SUPERFAMILY SSF160240 204 280 3.79E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 280 2.6E-22 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TSIB_1144 6afe037bc278d1bab4c55c9120ffcd6c 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 2.5E-78 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSIB_1990 8dd4156cfeed9e524abe6c01d5c71fe3 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 104 5.0E-35 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TSIB_1990 8dd4156cfeed9e524abe6c01d5c71fe3 126 Pfam PF04322 Protein of unknown function (DUF473) 1 112 4.7E-37 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TSIB_0560 0bb6b51ef8c070921b70361394af77d3 87 SUPERFAMILY SSF88697 39 85 8.95E-9 T 23-10-2018 IPR015947 PUA-like superfamily TSIB_0560 0bb6b51ef8c070921b70361394af77d3 87 Gene3D G3DSA:3.10.590.10 27 86 9.8E-18 T 23-10-2018 TSIB_0560 0bb6b51ef8c070921b70361394af77d3 87 SUPERFAMILY SSF160991 5 43 8.24E-6 T 23-10-2018 TSIB_1258 b3a29cec7278375b8aabce28786c28c1 171 Pfam PF02632 BioY family 27 166 9.9E-37 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSIB_1258 b3a29cec7278375b8aabce28786c28c1 171 PIRSF PIRSF016661 1 171 4.5E-46 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSIB_1258 b3a29cec7278375b8aabce28786c28c1 171 Gene3D G3DSA:1.10.1760.20 1 170 5.4E-52 T 23-10-2018 TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 Gene3D G3DSA:3.40.640.10 84 352 6.8E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 SUPERFAMILY SSF53383 6 448 2.29E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 Pfam PF02347 Glycine cleavage system P-protein 6 443 1.3E-121 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 6 448 47.223 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 PIRSF PIRSF006815 6 449 7.8E-159 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSIB_0937 9b6575c2778384696d96e0a362fcbcaa 454 Gene3D G3DSA:3.90.1150.10 73 444 6.8E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_0179 5270a9900ebe8c7fc243feb65c4967ae 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 264 6.6E-39 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSIB_1030 92b96802ba28d45461e6cb4e80e2b4be 354 Pfam PF05763 Protein of unknown function (DUF835) 228 353 1.3E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_1102 4ac00e4ceb88b0d6ff3ac3695f789eef 129 Pfam PF08004 Protein of unknown function (DUF1699) 19 116 2.1E-9 T 23-10-2018 IPR012546 Protein of unknown function DUF1699 TSIB_1102 4ac00e4ceb88b0d6ff3ac3695f789eef 129 Gene3D G3DSA:1.10.10.60 85 128 3.4E-9 T 23-10-2018 TSIB_1102 4ac00e4ceb88b0d6ff3ac3695f789eef 129 SUPERFAMILY SSF46689 85 125 2.87E-6 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSIB_2046 86d4be059de8464e438214e0d600fac2 74 Pfam PF01954 Protein of unknown function DUF104 1 56 1.2E-19 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TSIB_2046 86d4be059de8464e438214e0d600fac2 74 Gene3D G3DSA:4.10.1150.10 1 67 2.0E-16 T 23-10-2018 IPR024069 AF2212-like domain superfamily TSIB_2046 86d4be059de8464e438214e0d600fac2 74 SUPERFAMILY SSF141694 1 58 5.23E-16 T 23-10-2018 TSIB_1304 cf6b7334fc9ac01835129a52bd72ebbd 151 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 11 137 2.9E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TSIB_1642 86cc2317b1295bcc6fcb535eba400d85 110 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 1 106 5.4E-35 T 23-10-2018 IPR011719 Conserved hypothetical protein CHP02058 TSIB_1642 86cc2317b1295bcc6fcb535eba400d85 110 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 1 106 5.2E-25 T 23-10-2018 IPR011719 Conserved hypothetical protein CHP02058 TSIB_1642 86cc2317b1295bcc6fcb535eba400d85 110 Gene3D G3DSA:3.30.1330.20 1 110 7.6E-38 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TSIB_1345 22c2c3441a2dd9d8478eeab434a97bc7 85 Gene3D G3DSA:2.20.25.30 9 85 2.1E-32 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1345 22c2c3441a2dd9d8478eeab434a97bc7 85 Pfam PF01780 Ribosomal L37ae protein family 3 83 4.1E-35 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1345 22c2c3441a2dd9d8478eeab434a97bc7 85 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 82 2.5E-38 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1345 22c2c3441a2dd9d8478eeab434a97bc7 85 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.692 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSIB_1345 22c2c3441a2dd9d8478eeab434a97bc7 85 SUPERFAMILY SSF57829 10 80 1.28E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSIB_0037 92accf974306b4ab434df691004c2f9a 205 Pfam PF04021 Class III signal peptide 6 32 1.4E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TSIB_1629 adb5bdca38ff5b6c97e3dc8c6812da25 256 Pfam PF02596 Uncharacterised ArCR, COG2043 13 219 5.7E-27 T 23-10-2018 IPR003748 Protein of unknown function DUF169 TSIB_1172 39a3bc1c1107535655c6876049b365f5 216 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 153 186 9.1E-6 T 23-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TSIB_1172 39a3bc1c1107535655c6876049b365f5 216 Pfam PF14358 Domain of unknown function (DUF4405) 17 80 7.3E-14 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 TSIB_0322 6e68c0f640857164801885b6446bd4c9 121 Gene3D G3DSA:3.40.50.1010 1 107 2.7E-23 T 23-10-2018 TSIB_0322 6e68c0f640857164801885b6446bd4c9 121 SUPERFAMILY SSF88723 1 102 4.22E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily TSIB_0639 3aba688d6166d64ee25a63eab321179f 93 Gene3D G3DSA:1.10.10.1100 1 69 1.8E-22 T 23-10-2018 TSIB_0639 3aba688d6166d64ee25a63eab321179f 93 Pfam PF04324 BFD-like [2Fe-2S] binding domain 8 60 5.6E-14 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSIB_1917 5d94a8606232a52f5c1537e8e0e01608 168 PIRSF PIRSF019239 4 168 5.4E-55 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_1917 5d94a8606232a52f5c1537e8e0e01608 168 Pfam PF01899 Na+/H+ ion antiporter subunit 15 164 1.1E-46 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSIB_1109 7637303f099f48c9f7f7dc76871ab746 387 Gene3D G3DSA:3.40.50.300 2 184 1.8E-13 T 23-10-2018 TSIB_1050 cad26c8a8648ba5d8ea4cc386f6ffff3 230 SUPERFAMILY SSF63999 48 130 1.22E-9 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TSIB_1050 cad26c8a8648ba5d8ea4cc386f6ffff3 230 Pfam PF01973 Protein of unknown function DUF115 44 185 1.4E-35 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like TSIB_1050 cad26c8a8648ba5d8ea4cc386f6ffff3 230 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 223 35.638 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSIB_0374 c3d46bcd4248fcd3089eda3a29f0d0d4 766 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 60 470 1.4E-111 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TSIB_0374 c3d46bcd4248fcd3089eda3a29f0d0d4 766 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 144 450 4.1E-56 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSIB_0374 c3d46bcd4248fcd3089eda3a29f0d0d4 766 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 462 688 1.5E-28 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSIB_1251 cdf8e9aa7df070e07bdce31beaaa346e 184 Pfam PF06510 Protein of unknown function (DUF1102) 43 180 8.3E-43 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 TSIB_1078 00725561ec7c42d4723d3bdab7f97ba3 342 Gene3D G3DSA:1.20.1250.20 1 333 2.3E-26 T 23-10-2018 TSIB_1078 00725561ec7c42d4723d3bdab7f97ba3 342 SUPERFAMILY SSF103473 6 336 5.62E-29 T 23-10-2018 IPR036259 MFS transporter superfamily TSIB_1342 a62bb7ed8fdca1bba1cd836e5358951f 80 Gene3D G3DSA:3.30.310.50 1 80 4.3E-26 T 23-10-2018 TSIB_1342 a62bb7ed8fdca1bba1cd836e5358951f 80 Pfam PF09341 Transcription factor Pcc1 7 78 5.0E-15 T 23-10-2018 IPR015419 CTAG/Pcc1 family TSIB_1856 2fe6aa857f797b4a807239b9da4e7c17 147 Gene3D G3DSA:3.90.1170.40 3 138 1.5E-48 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSIB_1856 2fe6aa857f797b4a807239b9da4e7c17 147 SUPERFAMILY SSF54690 9 139 1.18E-45 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSIB_1856 2fe6aa857f797b4a807239b9da4e7c17 147 Pfam PF02391 MoaE protein 10 119 5.0E-36 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSIB_0144 2c4ac10ffa1bc9d7439e19300926007b 261 Pfam PF12698 ABC-2 family transporter protein 31 249 7.3E-18 T 23-10-2018 TSIB_1553 55ced3afe82a70d89cb9178024a3f3ad 134 Gene3D G3DSA:2.30.130.60 74 132 4.0E-8 T 23-10-2018 TSIB_1553 55ced3afe82a70d89cb9178024a3f3ad 134 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 83 131 2.0E-13 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain TSIB_0088 8cb9fa826f56a5214e4450724fba8cf8 263 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 262 4.0E-33 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TSIB_0088 8cb9fa826f56a5214e4450724fba8cf8 263 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 103 3.0E-20 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TSIB_0088 8cb9fa826f56a5214e4450724fba8cf8 263 Pfam PF10869 Protein of unknown function (DUF2666) 4 116 8.7E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TSIB_0088 8cb9fa826f56a5214e4450724fba8cf8 263 Pfam PF10869 Protein of unknown function (DUF2666) 139 262 3.5E-45 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TSIB_1570 5e496315680ded358c6c8335fdc75023 242 Gene3D G3DSA:3.40.50.880 1 242 2.4E-61 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1570 5e496315680ded358c6c8335fdc75023 242 Pfam PF07722 Peptidase C26 3 216 3.4E-46 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TSIB_1570 5e496315680ded358c6c8335fdc75023 242 SUPERFAMILY SSF52317 31 241 4.28E-37 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1437 3689aa847842ed2c545033e650e58def 280 SUPERFAMILY SSF53613 1 251 7.79E-33 T 23-10-2018 IPR029056 Ribokinase-like TSIB_1437 3689aa847842ed2c545033e650e58def 280 Pfam PF00294 pfkB family carbohydrate kinase 169 250 5.9E-6 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TSIB_1437 3689aa847842ed2c545033e650e58def 280 Gene3D G3DSA:3.40.1190.20 1 271 2.7E-83 T 23-10-2018 IPR029056 Ribokinase-like TSIB_0513 80fe3e076d448a24ebf45f9aa13d98ef 335 Gene3D G3DSA:3.40.190.10 164 324 1.3E-20 T 23-10-2018 TSIB_0513 80fe3e076d448a24ebf45f9aa13d98ef 335 SUPERFAMILY SSF53850 72 281 1.54E-23 T 23-10-2018 TSIB_0513 80fe3e076d448a24ebf45f9aa13d98ef 335 PIRSF PIRSF012876 1 327 1.9E-70 T 23-10-2018 IPR014466 Predicted transcriptional regulator, AF1742 type TSIB_0472 d56e1ce81fa3929cb48ed55150a8cd7a 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 1.3E-30 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 TSIB_1058 0e6f865ff44dfe77eac0902d626b2d94 252 SUPERFAMILY SSF56281 7 250 3.28E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1058 0e6f865ff44dfe77eac0902d626b2d94 252 Pfam PF12706 Beta-lactamase superfamily domain 54 219 1.9E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1058 0e6f865ff44dfe77eac0902d626b2d94 252 SMART SM00849 41 218 2.5E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TSIB_1058 0e6f865ff44dfe77eac0902d626b2d94 252 Gene3D G3DSA:3.60.15.10 5 252 2.3E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSIB_1651 44dc653e44766033a5f080da6fff4c42 129 SUPERFAMILY SSF141322 65 126 1.31E-8 T 23-10-2018 TSIB_1651 44dc653e44766033a5f080da6fff4c42 129 Gene3D G3DSA:2.40.50.140 65 129 5.9E-18 T 23-10-2018 TSIB_1651 44dc653e44766033a5f080da6fff4c42 129 Pfam PF01957 NfeD-like C-terminal, partner-binding 19 126 1.6E-12 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TSIB_1420 5a3ba28421ee9f80d1f45baab8e25d0f 348 Gene3D G3DSA:1.25.40.10 179 334 4.9E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1420 5a3ba28421ee9f80d1f45baab8e25d0f 348 Gene3D G3DSA:1.25.40.10 70 178 6.7E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0170 6cbff9b07a4510b5dacc495c7986c80e 154 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 13 150 1.3E-22 T 23-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSIB_1229 d51264279ebee9550dcee6bbbab26236 644 Gene3D G3DSA:1.50.10.20 39 204 5.3E-7 T 23-10-2018 TSIB_1229 d51264279ebee9550dcee6bbbab26236 644 SUPERFAMILY SSF48239 467 608 2.55E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_1229 d51264279ebee9550dcee6bbbab26236 644 Gene3D G3DSA:1.50.10.20 255 401 1.4E-6 T 23-10-2018 TSIB_1229 d51264279ebee9550dcee6bbbab26236 644 Gene3D G3DSA:1.50.10.20 452 638 1.5E-13 T 23-10-2018 TSIB_1229 d51264279ebee9550dcee6bbbab26236 644 SUPERFAMILY SSF48239 53 376 7.86E-17 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSIB_0447 dcdeffcbb65b717ccfa0c2e8e4fe998a 92 SUPERFAMILY SSF46785 34 79 2.83E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0847 171ef250ad4aa1a2c881f6321267ab22 135 Pfam PF01842 ACT domain 59 124 1.8E-12 T 23-10-2018 IPR002912 ACT domain TSIB_0847 171ef250ad4aa1a2c881f6321267ab22 135 Gene3D G3DSA:3.30.70.260 47 131 2.4E-15 T 23-10-2018 TSIB_0847 171ef250ad4aa1a2c881f6321267ab22 135 SUPERFAMILY SSF55021 57 131 3.31E-13 T 23-10-2018 TSIB_0242 4e7839f595f4f51b9498ad1c10e0068e 196 Pfam PF00149 Calcineurin-like phosphoesterase 25 130 1.1E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSIB_0242 4e7839f595f4f51b9498ad1c10e0068e 196 SUPERFAMILY SSF56300 25 161 1.82E-18 T 23-10-2018 TSIB_0242 4e7839f595f4f51b9498ad1c10e0068e 196 Gene3D G3DSA:3.60.21.10 25 167 2.3E-11 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TSIB_0375 78c63128a937961b63cb2fb91cd7a57d 149 Pfam PF08905 Domain of unknown function (DUF1850) 42 119 1.1E-10 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 TSIB_1504 aee020aa8a712782eb7ec4f509ad616a 494 Pfam PF02386 Cation transport protein 59 479 4.0E-61 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TSIB_1504 aee020aa8a712782eb7ec4f509ad616a 494 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 470 8.6E-104 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TSIB_1526 5a51b84d895aca5f1a9a616f65ca259a 102 Gene3D G3DSA:2.40.30.10 14 102 9.9E-19 T 23-10-2018 TSIB_1526 5a51b84d895aca5f1a9a616f65ca259a 102 Pfam PF14578 Elongation factor Tu domain 4 23 97 3.3E-16 T 23-10-2018 IPR029459 Elongation factor Tu-type domain TSIB_1526 5a51b84d895aca5f1a9a616f65ca259a 102 SUPERFAMILY SSF50447 20 101 1.34E-9 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSIB_0076 42a856af2d883b81d1f0c89830898a46 369 Pfam PF13026 Protein of unknown function (DUF3887) 31 113 1.9E-10 T 23-10-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 TSIB_0752 e70e010702b2222046e59e71ac693b72 264 Pfam PF07722 Peptidase C26 5 222 2.8E-56 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TSIB_0752 e70e010702b2222046e59e71ac693b72 264 SUPERFAMILY SSF52317 16 248 1.94E-31 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_0752 e70e010702b2222046e59e71ac693b72 264 Gene3D G3DSA:3.40.50.880 1 250 2.2E-65 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TSIB_1474 ad74759f37992e27ac22a02aef0357f0 194 Pfam PF06195 Protein of unknown function (DUF996) 31 170 1.3E-30 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TSIB_1929 3668ac478963736d0dfce9509b68f869 192 SUPERFAMILY SSF48371 28 159 5.76E-15 T 23-10-2018 IPR016024 Armadillo-type fold TSIB_1929 3668ac478963736d0dfce9509b68f869 192 Gene3D G3DSA:1.25.10.10 8 165 2.1E-11 T 23-10-2018 IPR011989 Armadillo-like helical TSIB_1059 521ce566567681a7bea1dfb4358d2da0 191 SUPERFAMILY SSF55469 4 187 6.54E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1059 521ce566567681a7bea1dfb4358d2da0 191 Pfam PF00881 Nitroreductase family 7 164 1.4E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSIB_1059 521ce566567681a7bea1dfb4358d2da0 191 Gene3D G3DSA:3.40.109.10 1 189 1.2E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSIB_1426 c243d551a7e576089aec99fd2b6683a1 174 Pfam PF03692 Putative zinc- or iron-chelating domain 26 129 4.2E-15 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TSIB_1293 4282a72e15daf945c293cb822510b36f 116 Pfam PF03334 Na+/H+ antiporter subunit 9 97 9.2E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_1293 4282a72e15daf945c293cb822510b36f 116 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 8 112 4.1E-33 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSIB_2034 90e403e22b7099c551b10ddc8d443c42 421 Gene3D G3DSA:3.40.50.300 9 151 3.9E-6 T 23-10-2018 TSIB_2034 90e403e22b7099c551b10ddc8d443c42 421 SUPERFAMILY SSF52540 17 155 1.8E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1327 319e82c7337c38f637dc393266339914 87 Pfam PF01169 Uncharacterized protein family UPF0016 7 79 3.3E-22 T 23-10-2018 IPR001727 Gdt1 family TSIB_0854 a376b38792b0b6c7b17667fc75e4aa99 310 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 15 293 3.5E-22 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 ProSitePatterns PS00324 Aspartokinase signature. 12 20 - T 23-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 Pfam PF00696 Amino acid kinase family 10 273 4.7E-46 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 TIGRFAM TIGR02078 AspKin_pair: putative Pyrococcus aspartate kinase subunit 11 350 2.1E-106 T 23-10-2018 IPR011819 Pyrococcus aspartate kinase subunit, putative TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 9 312 1.9E-66 T 23-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 Gene3D G3DSA:3.40.1160.10 10 287 1.8E-69 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_1602 5136e8394a9c30da45fbca54ba1a3bc9 351 SUPERFAMILY SSF53633 10 286 6.55E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSIB_0009 9330e9506d9f5865295d4e4093efb49c 432 Pfam PF01882 Protein of unknown function DUF58 182 260 1.1E-18 T 23-10-2018 IPR002881 Domain of unknown function DUF58 TSIB_1983 ed8d6a8a256a301478723f500bf4128f 311 SUPERFAMILY SSF52540 2 225 4.7E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSIB_1983 ed8d6a8a256a301478723f500bf4128f 311 SMART SM00382 30 214 3.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TSIB_1983 ed8d6a8a256a301478723f500bf4128f 311 Pfam PF00005 ABC transporter 26 165 8.1E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSIB_1983 ed8d6a8a256a301478723f500bf4128f 311 Gene3D G3DSA:3.40.50.300 1 239 9.2E-53 T 23-10-2018 TSIB_1996 663073b6b7fd4dd8012043e3bcae3038 159 Pfam PF09670 CRISPR-associated protein (Cas_Cas02710) 23 115 1.3E-6 T 23-10-2018 TSIB_0412 ba1905ea907d721d4b63fbe77715018e 273 Pfam PF00950 ABC 3 transport family 4 266 1.7E-27 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSIB_0412 ba1905ea907d721d4b63fbe77715018e 273 SUPERFAMILY SSF81345 4 272 1.7E-14 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TSIB_1887 51eda114633b81495c98ac48bd4db10f 205 SUPERFAMILY SSF161098 7 187 2.35E-35 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1887 51eda114633b81495c98ac48bd4db10f 205 Gene3D G3DSA:1.10.3720.10 5 197 6.5E-30 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_1887 51eda114633b81495c98ac48bd4db10f 205 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 199 6.7E-23 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0314 53bd7e383b10b776b810c14c154e72f8 175 Pfam PF01956 Integral membrane protein DUF106 21 173 9.3E-28 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TSIB_0314 53bd7e383b10b776b810c14c154e72f8 175 SMART SM01415 19 174 1.1E-16 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TSIB_1583 b5a45587338af29b7723ecc230a314d9 560 Pfam PF03553 Na+/H+ antiporter family 167 496 8.2E-77 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TSIB_1279 4b2dd2d232c83a55b83e7321b69ba848 416 SUPERFAMILY SSF53383 13 412 2.31E-101 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSIB_1279 4b2dd2d232c83a55b83e7321b69ba848 416 Gene3D G3DSA:3.90.1150.10 31 407 2.1E-144 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSIB_1279 4b2dd2d232c83a55b83e7321b69ba848 416 Pfam PF00155 Aminotransferase class I and II 45 405 1.4E-44 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSIB_1279 4b2dd2d232c83a55b83e7321b69ba848 416 Gene3D G3DSA:3.40.640.10 79 304 2.1E-144 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSIB_0320 e8fbda9f5c3342b37edb72e2898d92bb 1058 SUPERFAMILY SSF48208 327 1004 8.5E-13 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSIB_0112 fabe47ac9d6598aeb68909d5c2e24c01 188 Pfam PF07758 Protein of unknown function (DUF1614) 10 187 9.0E-60 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 TSIB_0663 7fa90fb9b4b623f3772fffa1f28e9d6e 289 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 125 1.0E-10 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TSIB_0663 7fa90fb9b4b623f3772fffa1f28e9d6e 289 Gene3D G3DSA:3.90.1570.30 6 139 5.8E-6 T 23-10-2018 TSIB_1932 056a5b6925c8ab6245f661ade8138b4f 107 SUPERFAMILY SSF47598 8 47 2.22E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSIB_0802 a2839d34d8946ec2901d14cb92603ff5 122 SUPERFAMILY SSF103481 57 121 2.35E-6 T 23-10-2018 TSIB_0802 a2839d34d8946ec2901d14cb92603ff5 122 Pfam PF00892 EamA-like transporter family 30 121 1.1E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSIB_0493 ebe54b454d75d369cfaf01de8c900213 209 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 195 7.4E-47 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 TSIB_0716 abe273c9938f262e9cb426ba93e52cc4 59 Pfam PF03911 Sec61beta family 14 54 1.1E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSIB_0716 abe273c9938f262e9cb426ba93e52cc4 59 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 4 54 14.731 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG TSIB_0938 202566d60280d1940b8c69e5718e176d 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 134 1.0E-9 T 23-10-2018 TSIB_0938 202566d60280d1940b8c69e5718e176d 223 SUPERFAMILY SSF56784 1 184 1.21E-17 T 23-10-2018 IPR036412 HAD-like superfamily TSIB_0938 202566d60280d1940b8c69e5718e176d 223 Gene3D G3DSA:3.40.50.1000 2 143 4.4E-10 T 23-10-2018 IPR023214 HAD superfamily TSIB_0601 40b4a3a40dad116ffa916fbe8806673f 179 Gene3D G3DSA:1.20.1260.10 16 169 4.6E-21 T 23-10-2018 IPR012347 Ferritin-like TSIB_0601 40b4a3a40dad116ffa916fbe8806673f 179 SUPERFAMILY SSF47240 22 163 6.71E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily TSIB_0601 40b4a3a40dad116ffa916fbe8806673f 179 Pfam PF02915 Rubrerythrin 26 164 3.9E-9 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSIB_1891 37f079b669c3c8aa38a91b2c881db9a6 269 Pfam PF02535 ZIP Zinc transporter 124 264 4.4E-19 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSIB_1303 60c160ac0fb4fd423c56e2189f4c3dbb 120 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 117 3.2E-25 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSIB_0405 90610b4311bda7024b625b91d9a6af95 99 Pfam PF04930 FUN14 family 13 96 5.3E-14 T 23-10-2018 IPR007014 FUN14 TSIB_0840 df7312ac1d039be0a0b89d34f8742084 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 88 1.4E-14 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSIB_0783 bfefb6d0f80c797d9b49e0bad06e555b 158 Pfam PF01917 Archaebacterial flagellin 15 154 2.7E-16 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TSIB_0764 2839d57ed7b281cede71c1bf34ef7238 73 Gene3D G3DSA:2.30.30.100 4 73 1.5E-31 T 23-10-2018 TSIB_0764 2839d57ed7b281cede71c1bf34ef7238 73 SUPERFAMILY SSF50182 8 72 2.94E-29 T 23-10-2018 IPR010920 LSM domain superfamily TSIB_0042 8ad3984ad9ba1fb20d991845da12b806 1096 Pfam PF10102 Domain of unknown function (DUF2341) 542 627 4.0E-15 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TSIB_0042 8ad3984ad9ba1fb20d991845da12b806 1096 Pfam PF10102 Domain of unknown function (DUF2341) 365 440 3.4E-10 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TSIB_0178 606505fa628616cedcdb1c5b366afdb5 323 Gene3D G3DSA:3.40.50.1980 23 181 5.7E-25 T 23-10-2018 TSIB_0178 606505fa628616cedcdb1c5b366afdb5 323 SUPERFAMILY SSF53807 23 284 5.89E-39 T 23-10-2018 TSIB_0178 606505fa628616cedcdb1c5b366afdb5 323 Pfam PF01297 Zinc-uptake complex component A periplasmic 27 282 6.0E-29 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSIB_1571 4f48800977f9f849a595c2b380592bda 457 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 96 344 2.3E-31 T 23-10-2018 IPR010839 Acyclic terpene utilisation TSIB_0970 30e64fc3fddbadb573dac8825cb1c0a0 378 Gene3D G3DSA:3.40.1280.30 92 274 6.4E-8 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily TSIB_0970 30e64fc3fddbadb573dac8825cb1c0a0 378 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 138 232 1.4E-6 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TSIB_0970 30e64fc3fddbadb573dac8825cb1c0a0 378 PIRSF PIRSF018978 3 378 6.5E-157 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 TSIB_0805 b9924ef8b6e8bae4825090b2ffc79aa1 123 PIRSF PIRSF006606 1 123 3.3E-49 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TSIB_0805 b9924ef8b6e8bae4825090b2ffc79aa1 123 Pfam PF04009 Protein of unknown function (DUF356) 1 105 3.7E-36 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TSIB_1212 486c24924838af13ecfbcc3337f68274 61 Pfam PF13396 Phospholipase_D-nuclease N-terminal 18 57 1.5E-7 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal TSIB_1141 dba7b513bef9460f3495539c13777267 159 Pfam PF00156 Phosphoribosyl transferase domain 18 151 7.4E-27 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSIB_1141 dba7b513bef9460f3495539c13777267 159 SUPERFAMILY SSF53271 3 145 7.74E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TSIB_1141 dba7b513bef9460f3495539c13777267 159 Gene3D G3DSA:3.40.50.2020 1 153 2.7E-52 T 23-10-2018 TSIB_1346 ddcba9bf52f430ed27ecb5259242d6f9 106 Pfam PF05763 Protein of unknown function (DUF835) 2 102 1.9E-15 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_0972 1e454d8d154957df0d4c441b82048db0 292 Gene3D G3DSA:3.30.2010.10 61 150 5.4E-34 T 23-10-2018 TSIB_0972 1e454d8d154957df0d4c441b82048db0 292 Pfam PF01435 Peptidase family M48 68 284 2.9E-37 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSIB_0972 1e454d8d154957df0d4c441b82048db0 292 Hamap MF_00188 Protease HtpX [htpX]. 6 284 31.02 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TSIB_0537 321afc1495660494ec5b022adbfcab2c 158 Pfam PF06695 Putative small multi-drug export protein 20 146 2.5E-30 T 23-10-2018 IPR009577 Putative small multi-drug export TSIB_0880 5e9a64967a010d90c1e1766d4a6c16c4 532 Pfam PF03553 Na+/H+ antiporter family 156 485 6.1E-71 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TSIB_1928 f8288f248835d0bef22e2a60c5e99886 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 8 77 9.0E-7 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA TSIB_1099 7ac68c9fb9a2cd423ac08686965f99b9 232 Gene3D G3DSA:3.30.1490.20 39 116 1.4E-89 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSIB_1099 7ac68c9fb9a2cd423ac08686965f99b9 232 Pfam PF13549 ATP-grasp domain 16 231 1.5E-81 T 23-10-2018 TSIB_1099 7ac68c9fb9a2cd423ac08686965f99b9 232 SUPERFAMILY SSF56059 23 232 2.12E-50 T 23-10-2018 TSIB_1099 7ac68c9fb9a2cd423ac08686965f99b9 232 Gene3D G3DSA:3.30.470.20 21 230 1.4E-89 T 23-10-2018 TSIB_0719 da51c62e98b8c2e78ab3e682ebec7f49 126 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0719 da51c62e98b8c2e78ab3e682ebec7f49 126 Pfam PF01092 Ribosomal protein S6e 4 124 4.9E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0719 da51c62e98b8c2e78ab3e682ebec7f49 126 SMART SM01405 4 126 1.2E-52 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSIB_0719 da51c62e98b8c2e78ab3e682ebec7f49 126 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 19.009 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 TSIB_1653 afdfa6932d7a6be3265140a7379234ed 363 Pfam PF01170 Putative RNA methylase family UPF0020 173 320 1.2E-11 T 23-10-2018 IPR000241 Putative RNA methylase domain TSIB_1653 afdfa6932d7a6be3265140a7379234ed 363 SUPERFAMILY SSF53335 171 338 1.04E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSIB_1653 afdfa6932d7a6be3265140a7379234ed 363 Gene3D G3DSA:3.40.50.150 169 353 1.2E-25 T 23-10-2018 TSIB_0855 9f6f95e753b181ee3fdcd124b2269a98 378 Gene3D G3DSA:3.40.50.2000 5 361 1.7E-90 T 23-10-2018 TSIB_0855 9f6f95e753b181ee3fdcd124b2269a98 378 Gene3D G3DSA:3.40.50.2000 179 360 1.7E-90 T 23-10-2018 TSIB_0855 9f6f95e753b181ee3fdcd124b2269a98 378 Pfam PF00534 Glycosyl transferases group 1 198 352 1.1E-45 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TSIB_0855 9f6f95e753b181ee3fdcd124b2269a98 378 SUPERFAMILY SSF53756 1 375 1.37E-96 T 23-10-2018 TSIB_0855 9f6f95e753b181ee3fdcd124b2269a98 378 Pfam PF13439 Glycosyltransferase Family 4 14 182 3.5E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSIB_1206 e5844a7fdb55d8e438882db90b05dc55 241 Pfam PF02517 CAAX protease self-immunity 137 236 3.8E-15 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TSIB_1595 963fe56cafa81eeac0a3d32b50ec5410 70 Gene3D G3DSA:1.10.20.10 2 70 8.8E-23 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1595 963fe56cafa81eeac0a3d32b50ec5410 70 SUPERFAMILY SSF47113 6 69 5.78E-19 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TSIB_1595 963fe56cafa81eeac0a3d32b50ec5410 70 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 5 68 4.2E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TSIB_1595 963fe56cafa81eeac0a3d32b50ec5410 70 SMART SM00803 19 69 0.0079 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 TSIB_0372 266d5b6c8da95ca13b4dcbbe2fc66bcb 403 SUPERFAMILY SSF53743 5 282 1.7E-36 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 TSIB_0327 0bbfd4f41a85d767b8859d17134c59b5 613 Gene3D G3DSA:2.60.120.180 353 605 2.1E-36 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSIB_0327 0bbfd4f41a85d767b8859d17134c59b5 613 Gene3D G3DSA:2.60.120.180 1 141 1.1E-15 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSIB_1181 9c9d1af2df719458e1c10d0484d0084f 356 SUPERFAMILY SSF48452 15 182 4.55E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1181 9c9d1af2df719458e1c10d0484d0084f 356 Gene3D G3DSA:1.25.40.10 1 356 9.6E-66 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_1622 b8b29c95ac859fe4e55275cb05b76a51 175 Pfam PF06496 Protein of unknown function (DUF1097) 13 160 4.6E-8 T 23-10-2018 IPR009476 Protein of unknown function DUF1097 TSIB_0744 d42c32e9f75e2b02efcdc0e7cc893865 419 Hamap MF_02096 DNA repair protein. 9 415 37.314 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 TSIB_0744 d42c32e9f75e2b02efcdc0e7cc893865 419 Pfam PF04895 Archaeal Nre, C-terminal 305 415 3.4E-36 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal TSIB_0744 d42c32e9f75e2b02efcdc0e7cc893865 419 Pfam PF04894 Archaeal Nre, N-terminal 25 292 4.5E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal TSIB_0020 50111ee23b22e7bc87b5d0b81f2562c9 383 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 6 373 1.1E-38 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSIB_0795 4a156e4621163d80d8121f5872d87bc9 154 Pfam PF13175 AAA ATPase domain 10 90 4.0E-17 T 23-10-2018 TSIB_0749 67f17f2c904ce9ee08e6f238de9db900 57 SMART SM00355 18 41 8.6E-4 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TSIB_0749 67f17f2c904ce9ee08e6f238de9db900 57 Gene3D G3DSA:3.30.160.60 3 56 1.5E-5 T 23-10-2018 TSIB_0266 816fa8c3baa20aaf398808a6e5913328 99 Pfam PF04242 Protein of unknown function (DUF424) 8 98 3.2E-31 T 23-10-2018 IPR007355 Protein of unknown function DUF424 TSIB_0266 816fa8c3baa20aaf398808a6e5913328 99 Gene3D G3DSA:3.30.1860.10 1 98 4.8E-34 T 23-10-2018 TSIB_0360 4473c7588346a814af342a1e6498ac25 281 Gene3D G3DSA:1.10.3720.10 4 268 1.3E-58 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0360 4473c7588346a814af342a1e6498ac25 281 SUPERFAMILY SSF161098 12 274 1.5E-64 T 23-10-2018 IPR035906 MetI-like superfamily TSIB_0360 4473c7588346a814af342a1e6498ac25 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 270 6.8E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0199 16f15dd4fccfc77eb22ecf2a47d4f470 99 Pfam PF04892 VanZ like family 29 91 1.1E-9 T 23-10-2018 IPR006976 VanZ-like TSIB_0328 a6336924461ed88176a24458d928175c 507 Gene3D G3DSA:2.60.120.180 43 339 3.3E-41 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSIB_0328 a6336924461ed88176a24458d928175c 507 Gene3D G3DSA:2.60.120.180 379 506 8.6E-14 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSIB_1283 c56d047943231abf4aaec344e17bf292 322 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 200 213 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1283 c56d047943231abf4aaec344e17bf292 322 Pfam PF00146 NADH dehydrogenase 17 317 5.0E-66 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSIB_1354 23c8a8235257633b91dea4f507da99a5 385 Pfam PF05559 Protein of unknown function (DUF763) 5 339 4.7E-124 T 23-10-2018 IPR008482 Protein of unknown function DUF763 TSIB_0083 25df3422fbbd0e2de5702e0ebc8f716c 108 Pfam PF14367 Domain of unknown function (DUF4411) 3 107 1.4E-10 T 23-10-2018 IPR016541 Uncharacterised conserved protein UCP008505 TSIB_1933 9356520dc130184fd43c433bc803b353 72 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 1.2E-18 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 TSIB_0788 bfa93171ce43676d9822f64f4d1afeb8 106 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 7 94 9.8E-36 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 TSIB_0788 bfa93171ce43676d9822f64f4d1afeb8 106 SUPERFAMILY SSF46785 15 105 9.1E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSIB_0450 2c709aa526ee5c5e02b08c17a38b51a0 374 Gene3D G3DSA:1.20.1530.20 1 374 1.7E-90 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TSIB_0450 2c709aa526ee5c5e02b08c17a38b51a0 374 Pfam PF00999 Sodium/hydrogen exchanger family 10 370 1.6E-69 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 176 5.8E-52 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 Gene3D G3DSA:3.90.950.10 1 181 9.7E-64 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 Pfam PF02545 Maf-like protein 2 176 6.2E-55 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 PIRSF PIRSF006305 1 183 1.8E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 SUPERFAMILY SSF52972 1 175 1.48E-55 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSIB_1404 4f6155eeb64879e0c5e8e063c109b2e5 185 Hamap MF_00528 Septum formation protein Maf [maf]. 2 184 29.786 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TSIB_1806 5485779fe32423a0585bac18144c29f5 171 Pfam PF03692 Putative zinc- or iron-chelating domain 15 126 1.5E-14 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TSIB_0458 38bf5f3bd3c9ae588507a359370daa10 73 Pfam PF01998 Protein of unknown function DUF131 20 65 2.3E-15 T 23-10-2018 IPR002849 Protein of unknown function DUF131 TSIB_0136 c4358a8937400502f949328651523c3f 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 4.1E-61 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSIB_0725 ef6eeeebdaddf0981cc966dc2f77c0e2 268 Pfam PF01889 Membrane protein of unknown function DUF63 3 268 5.2E-91 T 23-10-2018 IPR002749 Protein of unknown function DUF63 TSIB_0498 b6dffa164a2763b1341ee2b18216efb3 167 SUPERFAMILY SSF159902 11 166 1.11E-71 T 23-10-2018 TSIB_0498 b6dffa164a2763b1341ee2b18216efb3 167 Pfam PF09638 Ph1570 protein 11 165 8.8E-63 T 23-10-2018 IPR023110 PH1570-like domain TSIB_0498 b6dffa164a2763b1341ee2b18216efb3 167 Gene3D G3DSA:3.40.1600.10 3 166 6.9E-67 T 23-10-2018 IPR036807 PH1570-like superfamily TSIB_1043 2c851c9fad9779abe9ab5151e335dfe4 411 Pfam PF01384 Phosphate transporter family 27 400 1.7E-110 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TSIB_0092 1da8d6a247be5156b1c06fe33ba8a891 306 Pfam PF01384 Phosphate transporter family 15 297 7.2E-53 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TSIB_0232 da5390f53674379d0d673c8de4e05480 577 Pfam PF02554 Carbon starvation protein CstA 1 359 3.8E-109 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TSIB_0232 da5390f53674379d0d673c8de4e05480 577 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 403 523 2.3E-29 T 23-10-2018 IPR025299 CstA, C-terminal domain TSIB_0172 2f45e46048b78eeca8b53b74a21f9682 198 Pfam PF02517 CAAX protease self-immunity 111 185 3.1E-9 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TSIB_0977 4b994f954221e9fbf6bd72d0a2a2a73b 187 Pfam PF04493 Endonuclease V 12 132 2.4E-31 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TSIB_0977 4b994f954221e9fbf6bd72d0a2a2a73b 187 Gene3D G3DSA:3.30.2170.10 1 142 5.3E-35 T 23-10-2018 TSIB_1934 8e77676e81e95ccffbfc1f15a5b69ac6 93 Pfam PF14076 Domain of unknown function (DUF4258) 4 79 5.9E-12 T 23-10-2018 IPR025354 Protein of unknown function DUF4258 TSIB_1551 7f0f90f208f56c7476c810a091b077b2 326 Pfam PF12679 ABC-2 family transporter protein 12 325 4.5E-44 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TSIB_1679 399a27df8e737382988fa2f6d2eb45ac 160 Pfam PF09622 Putative integral membrane protein (DUF2391) 16 158 9.7E-14 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 TSIB_1313 3377252fbd3a5a1f446421027c81e1e5 368 Pfam PF05763 Protein of unknown function (DUF835) 229 364 2.1E-36 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_0164 b3b38a6055914f3c5bc131d5bafd1c69 202 Pfam PF03222 Tryptophan/tyrosine permease family 8 168 6.6E-20 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 TSIB_0164 b3b38a6055914f3c5bc131d5bafd1c69 202 Gene3D G3DSA:1.20.1740.10 1 201 4.8E-11 T 23-10-2018 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 44 63 3.8E-14 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 3.8E-14 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 15 36 3.8E-14 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 Pfam PF00209 Sodium:neurotransmitter symporter family 8 122 7.0E-23 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 Pfam PF00209 Sodium:neurotransmitter symporter family 144 450 3.0E-30 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TSIB_0632 6a30af4b325681bf9b73a422035fd0ef 521 SUPERFAMILY SSF161070 8 504 4.58E-104 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TSIB_1731 fb4a0ef289c5cec99be39141910ec77f 109 Gene3D G3DSA:3.40.1260.10 2 109 1.3E-14 T 23-10-2018 IPR027396 DsrEFH-like TSIB_1731 fb4a0ef289c5cec99be39141910ec77f 109 SUPERFAMILY SSF75169 2 104 1.77E-5 T 23-10-2018 IPR027396 DsrEFH-like TSIB_2018 cbe8f45944650ac62702655a11138ac1 414 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 405 8.6E-17 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TSIB_2018 cbe8f45944650ac62702655a11138ac1 414 Pfam PF01943 Polysaccharide biosynthesis protein 9 279 1.8E-28 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TSIB_0829 b5864e6d046130d4706e01b7522116a3 319 SMART SM00028 121 154 0.5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_0829 b5864e6d046130d4706e01b7522116a3 319 SMART SM00028 81 114 41.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSIB_0829 b5864e6d046130d4706e01b7522116a3 319 SUPERFAMILY SSF48452 78 219 4.25E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0829 b5864e6d046130d4706e01b7522116a3 319 Pfam PF13424 Tetratricopeptide repeat 84 150 1.1E-7 T 23-10-2018 TSIB_0829 b5864e6d046130d4706e01b7522116a3 319 Gene3D G3DSA:1.25.40.10 50 236 2.8E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0777 d5a050a6ba7de63ebe72e579b92b2471 291 Pfam PF03547 Membrane transport protein 20 115 2.1E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSIB_0777 d5a050a6ba7de63ebe72e579b92b2471 291 Pfam PF03547 Membrane transport protein 148 287 4.3E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSIB_0195 3f7ba44df94d8e84d5acec67aeaeb20d 194 Gene3D G3DSA:1.10.1760.20 1 192 5.7E-19 T 23-10-2018 TSIB_1386 0eab20c3ef0f4f4152ddfd1b3eac016d 327 Pfam PF01384 Phosphate transporter family 26 313 1.1E-68 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TSIB_0398 4a2e413a8af4916c6259ea3f226b0423 279 Pfam PF05763 Protein of unknown function (DUF835) 140 267 1.7E-35 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TSIB_1338 5d27997420e559c03c5566eb939fd1f4 110 Gene3D G3DSA:1.10.10.1220 1 88 3.3E-38 T 23-10-2018 TSIB_0262 94bd1dbbd3dddc9d738dccd53039e7ef 182 Pfam PF06197 Protein of unknown function (DUF998) 6 157 7.7E-13 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TSIB_0708 cc7cf6d6e26355fe589e7132410ca8c1 123 Pfam PF08661 Replication factor A protein 3 28 110 3.4E-5 T 23-10-2018 IPR013970 Replication factor A protein 3 GO:0003677|GO:0005634|GO:0006260|GO:0006281|GO:0006310 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174437|Reactome: R-HSA-176187|Reactome: R-HSA-3371453|Reactome: R-HSA-3371511|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6804756|Reactome: R-HSA-68962|Reactome: R-HSA-69166|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSIB_0708 cc7cf6d6e26355fe589e7132410ca8c1 123 SUPERFAMILY SSF50249 27 102 7.42E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSIB_1387 f5ae35d0604d2588fbe924a6ed747392 425 Gene3D G3DSA:3.40.1710.10 43 202 4.1E-34 T 23-10-2018 TSIB_1387 f5ae35d0604d2588fbe924a6ed747392 425 Pfam PF12698 ABC-2 family transporter protein 19 406 1.7E-40 T 23-10-2018 TSIB_0330 e78ad7d473b4e7d1f3d6459e1c644f88 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 330 1.8E-30 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSIB_0510 9f4c13ebca689a6d8852292b4e12e854 360 Pfam PF02073 Thermophilic metalloprotease (M29) 151 327 6.4E-11 T 23-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSIB_0510 9f4c13ebca689a6d8852292b4e12e854 360 SUPERFAMILY SSF144052 22 359 2.49E-42 T 23-10-2018 TSIB_0022 ecc5d57132180b19e8d34bc9f29389c8 204 Pfam PF12389 Camelysin metallo-endopeptidase 28 204 1.8E-9 T 23-10-2018 IPR022121 Peptidase M73, camelysin TSIB_1489 e16b578eacb23b0686b91beea23820d2 218 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 11 46 1.6E-6 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TSIB_1960 119c2cf1df7ce89918781463ff8bbd55 107 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 95 6.4E-21 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 TSIB_1294 30ee4bc435820699077845879ce186bc 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 25 76 6.0E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSIB_1912 86c65d13d429a4a2ccb1089407d14b7d 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 4 110 1.1E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSIB_1275 37b20562af84a5c219d224f713d4c0e3 128 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 106 1.8E-24 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 TSIB_0171 febf3ec50f9380a3ba0c4ca8b13a68be 223 Pfam PF13349 Putative adhesin 98 221 6.0E-10 T 23-10-2018 IPR025164 Putative adhesin TSIB_0499 1dd0fd076e128c18ea75430a18bdf6c6 329 Pfam PF01594 AI-2E family transporter 9 322 2.9E-38 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TSIB_1770 82e1ffb28be80a70a0385a0dc851be02 101 Gene3D G3DSA:3.30.720.70 1 101 2.2E-43 T 23-10-2018 TSIB_1814 27da642643d9164002c3467a2cdd1049 406 Pfam PF13529 Peptidase_C39 like family 234 380 9.8E-9 T 23-10-2018 IPR039564 Peptidase C39-like TSIB_1250 43bb0efb6a3d496a41bad398ee02bcac 168 Pfam PF06510 Protein of unknown function (DUF1102) 35 167 2.2E-40 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 TSIB_1319 2ef6c58135252f2a85698cd3ce84ac31 218 Pfam PF02361 Cobalt transport protein 2 193 5.0E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TSIB_0844 dd34c68e8ef9a4c47050063586fa343c 138 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 4 125 3.2E-27 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TSIB_1292 05ad900cb5ceb20ad32aa732550a03b4 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 80 1.1E-19 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TSIB_1411 bbc0be99c78948c3385d1c549b5b608f 394 SUPERFAMILY SSF48452 122 231 3.29E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSIB_0780 ad209787cf615a52b5408c83e9e20d38 570 Pfam PF00482 Type II secretion system (T2SS), protein F 89 216 1.0E-9 T 23-10-2018 IPR018076 Type II secretion system F domain TSIB_0780 ad209787cf615a52b5408c83e9e20d38 570 Pfam PF00482 Type II secretion system (T2SS), protein F 338 461 1.8E-7 T 23-10-2018 IPR018076 Type II secretion system F domain TSIB_1165 41d2457e175e7b1d0513e3fa65eb1fe9 662 Pfam PF04312 Protein of unknown function (DUF460) 209 349 1.8E-48 T 23-10-2018 IPR007408 Protein of unknown function DUF460 TSIB_0826 2f154e0e2f3bd2f433427a46ad934e4a 241 Pfam PF01963 TraB family 17 234 9.6E-15 T 23-10-2018 IPR002816 Pheromone shutdown, TraB TSIB_0810 a1a4bb2d73c335dd79c223a5fbc97698 237 Pfam PF12679 ABC-2 family transporter protein 36 229 4.8E-14 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085