locus-tag	class	description
A3L11_00050	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L11_00055	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A3L11_00070	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A3L11_00090	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A3L11_00095	ENOG4105CXT	aspartate transcarbamylase
A3L11_00100	ENOG4107ZCS	Phosphomethylpyrimidine kinase
A3L11_00135	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L11_00140	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L11_00150	ENOG4105NBF	ammecr1 domain protein
A3L11_00170	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A3L11_00175	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L11_00180	ENOG4105EHG	Permease protein
A3L11_00205	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A3L11_00215	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L11_00220	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L11_00225	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A3L11_00240	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L11_00270	ENOG4105EHU	Circadian clock protein KaiC
A3L11_00285	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3L11_00310	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L11_00335	ENOG4105DK7	lysyl-tRNA synthetase
A3L11_00340	ENOG4107QUY	Guanine deaminase
A3L11_00360	ENOG4105D44	asparaginase
A3L11_00365	ENOG4105C6X	Major Facilitator
A3L11_00370	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A3L11_00385	ENOG4105DJB	Major Facilitator Superfamily
A3L11_00390	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L11_00410	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A3L11_00420	ENOG4108UK2	deaminase
A3L11_00425	ENOG4105D0M	Protease HtpX homolog
A3L11_00460	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L11_00465	ENOG4105BZ8	glutamate synthase
A3L11_00480	ENOG4105CHR	reductase
A3L11_00490	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L11_00495	ENOG4105VG1	fes assembly suf system protein
A3L11_00505	ENOG4108JVH	Protein of unknown function DUF43
A3L11_00530	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L11_00535	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3L11_00560	ENOG4105DDR	sarcosine oxidase (Beta subunit)
A3L11_00570	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3L11_00580	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A3L11_00630	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L11_00645	ENOG4105CK7	Sodium proline symporter
A3L11_00670	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_00700	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A3L11_00705	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L11_00710	ENOG4108UKZ	OsmC family
A3L11_00725	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L11_00730	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L11_00750	ENOG4105CHU	acetyl-coa acetyltransferase
A3L11_00830	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A3L11_00855	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L11_00880	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L11_00905	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L11_00910	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L11_00915	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L11_00920	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A3L11_00925	ENOG4105E2K	Glycosyl transferase (Group 1
A3L11_00930	ENOG4105BZ8	glutamate synthase
A3L11_00935	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L11_00965	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L11_00970	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L11_00975	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L11_00985	ENOG4108JQ7	(ABC) transporter
A3L11_01020	ENOG4105CJ1	ABC, transporter
A3L11_01025	ENOG4105VZ8	Transcriptional regulator
A3L11_01055	ENOG4105CHM	Aminotransferase
A3L11_01070	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L11_01075	ENOG4107QJE	Chromosome Partitioning Protein
A3L11_01085	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L11_01095	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3L11_01110	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3L11_01135	ENOG4105CJ1	ABC, transporter
A3L11_01180	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A3L11_01185	ENOG4107104	thymidine kinase
A3L11_01190	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L11_01225	ENOG4105D7K	pfkb domain protein
A3L11_01230	ENOG4106J7S	Glycosyl transferase, family 2
A3L11_01260	ENOG4108IJ9	(ABC) transporter
A3L11_01270	ENOG4105D1Z	hydroxypyruvate reductase
A3L11_01300	ENOG4105K4P	CoA-binding domain protein
A3L11_01330	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A3L11_01335	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L11_01350	ENOG41066FR	extracellular solute-binding protein
A3L11_01355	ENOG4108I5D	sulfate abc transporter
A3L11_01360	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L11_01365	ENOG4108R96	Methyltransferase, YaeB family
A3L11_01370	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L11_01440	ENOG4108J9M	Transporter
A3L11_01455	ENOG4105CWC	Acetylornithine deacetylase
A3L11_01465	ENOG4108JQ1	Dehydrogenase
A3L11_01475	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A3L11_01480	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A3L11_01485	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A3L11_01515	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3L11_01525	ENOG4105CJ3	phosphate transporter
A3L11_01540	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L11_01545	ENOG4105DDK	oxidoreductase, beta subunit
A3L11_01555	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L11_01560	ENOG4105DDK	oxidoreductase, beta subunit
A3L11_01570	ENOG4105QAX	Iron-sulfur
A3L11_01575	ENOG4105BZ8	glutamate synthase
A3L11_01585	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
A3L11_01590	ENOG4105QAX	Iron-sulfur
A3L11_01595	ENOG41080XS	Cobyrinic acid ac-diamide synthase
A3L11_01610	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A3L11_01615	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L11_01620	ENOG4105D1F	ATP-binding protein
A3L11_01645	ENOG4108RVA	ribokinase
A3L11_01655	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A3L11_01665	ENOG4108UUC	Protein of unknown function DUF99
A3L11_01670	ENOG4107YZX	Universal stress protein
A3L11_01695	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A3L11_01740	ENOG4105CIG	ABC transporter
A3L11_01770	ENOG4105EWK	phytoene
A3L11_01790	ENOG4107NFR	Fructose-1,6-bisphosphatase
A3L11_01810	ENOG4108VVK	transcriptional Regulator, AsnC
A3L11_01815	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L11_01830	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A3L11_01865	ENOG4107S6Z	Na H antiporter
A3L11_01870	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L11_01895	ENOG4105VAW	lrga family
A3L11_01900	ENOG41067MG	lrgb family
A3L11_01930	ENOG4108S8N	class II Aldolase
A3L11_01940	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A3L11_01950	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A3L11_02015	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A3L11_02020	ENOG4105VFR	signal peptidase
A3L11_02035	ENOG4108IGT	Dipeptidase
A3L11_02070	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L11_02095	ENOG4105CJ3	phosphate transporter
A3L11_02125	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L11_02135	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L11_02140	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L11_02145	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L11_02150	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L11_02170	ENOG4108BPK	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_02175	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L11_02185	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L11_02190	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L11_02195	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L11_02200	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L11_02205	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_02215	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L11_02220	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L11_02235	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
A3L11_02240	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L11_02245	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L11_02255	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L11_02260	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_02265	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L11_02270	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L11_02275	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_02300	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L11_02320	ENOG4105C3M	thioredoxin reductase
A3L11_02335	ENOG4108JPW	Aminotransferase
A3L11_02365	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L11_02395	ENOG4108VVK	transcriptional Regulator, AsnC
A3L11_02420	ENOG4108ZAF	Molybdopterin
A3L11_02430	ENOG4105D06	uba thif-type nad fad binding protein
A3L11_02470	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L11_02485	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L11_02495	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L11_02515	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L11_02565	ENOG4105EYW	Ion transport protein
A3L11_02590	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L11_02605	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L11_02610	ENOG4105D1H	recombination factor protein RarA
A3L11_02625	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3L11_02635	ENOG4105E5K	Alpha-amylase
A3L11_02690	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L11_02700	ENOG4105ERH	Fumarylacetoacetate hydrolase
A3L11_02720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3L11_02725	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A3L11_02760	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A3L11_02785	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L11_02805	ENOG4105CTD	carboxy-peptidase
A3L11_02825	ENOG4107SCK	Monooxygenase
A3L11_02830	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3L11_02855	ENOG4105E4P	ATPase (AAA
A3L11_02860	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L11_02900	ENOG4107TSN	permease
A3L11_02905	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A3L11_02930	ENOG4107RIQ	Sulfate adenylate transferase
A3L11_02950	ENOG4107RWR	Sodium hydrogen exchanger
A3L11_02975	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A3L11_02990	ENOG4107R56	PP-loop domain protein
A3L11_02995	ENOG4105DZ0	fad dependent oxidoreductase
A3L11_03000	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L11_03005	ENOG4107RWR	Sodium hydrogen exchanger
A3L11_03010	ENOG4107RWR	Sodium hydrogen exchanger
A3L11_03020	ENOG4105CUT	histidyl-tRNA synthetase
A3L11_03040	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L11_03050	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A3L11_03095	ENOG4105EHU	Circadian clock protein KaiC
A3L11_03105	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A3L11_03110	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L11_03120	ENOG4105C1A	potassium transporter peripheral membrane
A3L11_03140	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L11_03150	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L11_03155	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A3L11_03160	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
A3L11_03165	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L11_03170	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L11_03175	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A3L11_03195	ENOG4105CD3	dihydroorotase
A3L11_03210	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L11_03215	ENOG4105C3U	ABC transporter
A3L11_03220	ENOG4108JQ7	(ABC) transporter
A3L11_03230	ENOG4105C4K	Nad synthetase
A3L11_03240	ENOG4105C5F	glutamine synthetase
A3L11_03280	ENOG4105EHU	Circadian clock protein KaiC
A3L11_03300	ENOG4105DR4	Methyltransferase
A3L11_03310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L11_03320	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L11_03330	ENOG4105EPD	Oligopeptide transporter, Opt family
A3L11_03335	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L11_03340	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L11_03360	ENOG4105EG2	ABC transporter, permease
A3L11_03380	ENOG4108NGU	Transcriptional regulator
A3L11_03385	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L11_03415	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3L11_03425	ENOG4108IPJ	Membrane
A3L11_03445	ENOG41081HM	2'-5' rna ligase
A3L11_03465	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L11_03475	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A3L11_03495	ENOG41076QQ	Glycosyl transferase, family 2
A3L11_03500	ENOG4105CG5	Glycosyl transferase (Group 1
A3L11_03525	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A3L11_03540	ENOG4105CMR	udp-glucose 4-epimerase
A3L11_03565	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L11_03605	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L11_03625	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A3L11_03630	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A3L11_03650	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L11_03670	ENOG4108RJ9	Glycosyl transferase, family 2
A3L11_03680	ENOG4107R8N	Glycosyl transferase, family 2
A3L11_03685	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L11_03765	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L11_03775	ENOG4108IYU	L-aspartate oxidase
A3L11_03780	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A3L11_03790	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A3L11_03795	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A3L11_03800	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A3L11_03805	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A3L11_03815	ENOG4105C8V	SAICAR synthetase
A3L11_03820	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A3L11_03825	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A3L11_03830	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A3L11_03835	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A3L11_03855	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A3L11_03865	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L11_03880	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L11_03945	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A3L11_03970	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A3L11_03975	ENOG4105F0N	pyrophosphate phospho-hydrolase
A3L11_04035	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L11_04040	ENOG4105IIU	Aminopeptidase
A3L11_04120	ENOG4105K8R	UPF0145 protein
A3L11_04145	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L11_04160	ENOG4105D8X	mechanosensitive ion channel
A3L11_04205	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A3L11_04230	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3L11_04235	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3L11_04245	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A3L11_04295	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L11_04300	ENOG4106SMU	thiamine transporter membrane protein
A3L11_04330	ENOG4105NBF	ammecr1 domain protein
A3L11_04345	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L11_04365	ENOG4105CQ2	DNA polymerase
A3L11_04410	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L11_04435	ENOG4105VUN	Transcriptional regulator
A3L11_04440	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L11_04450	ENOG4108RWI	nicotinamidase
A3L11_04490	ENOG4105DQU	oxidoreductase, subunit beta
A3L11_04530	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L11_04540	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L11_04545	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L11_04550	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L11_04585	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L11_04590	ENOG4105D9Q	decarboxylase (Beta subunit)
A3L11_04595	ENOG4107QSA	Oxaloacetate decarboxylase
A3L11_04605	ENOG4105D8K	carboxyl transferase
A3L11_04640	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A3L11_04685	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L11_04700	ENOG4107QIZ	NADH dehydrogenase
A3L11_04735	ENOG4105C5R	Aminotransferase
A3L11_04780	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3L11_04790	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3L11_04795	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L11_04800	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3L11_04810	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3L11_04815	ENOG41082SA	50s ribosomal protein l29
A3L11_04820	ENOG4108ZJT	translation initiation factor, Sui1
A3L11_04830	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3L11_04835	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3L11_04840	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3L11_04850	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L11_04860	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3L11_04865	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A3L11_04880	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A3L11_04885	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3L11_04890	ENOG4105VPB	50S ribosomal protein L30
A3L11_04895	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3L11_04920	ENOG4108Z4J	Cytidine monophosphate kinase
A3L11_04935	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3L11_04940	ENOG4107Y49	methyltransferase
A3L11_04950	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L11_04955	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3L11_04960	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3L11_04980	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3L11_04985	ENOG4108UJD	30S ribosomal protein S9
A3L11_05010	ENOG4105CE9	30S ribosomal protein S2
A3L11_05045	ENOG4108YXU	transcriptional regulator AsnC family
A3L11_05055	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A3L11_05070	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L11_05085	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L11_05090	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L11_05105	ENOG4108I5U	Uridine phosphorylase
A3L11_05115	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A3L11_05125	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L11_05145	ENOG4108XIB	electron transport protein ysaA
A3L11_05150	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L11_05155	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A3L11_05170	ENOG4105EAH	synthase
A3L11_05175	ENOG4105C57	major facilitator superfamily
A3L11_05190	ENOG4105C8T	Leucyl-tRNA synthetase
A3L11_05205	ENOG4105DC7	peptidase M24
A3L11_05250	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L11_05265	ENOG4107RFW	hydrolase family 57
A3L11_05270	ENOG4108YZA	Nitrogen regulatory protein pii
A3L11_05280	ENOG4105C8J	)-transporter
A3L11_05285	ENOG4105D82	Glutamate dehydrogenase
A3L11_05300	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L11_05305	ENOG4105CY0	Metallo-Beta-Lactamase
A3L11_05320	ENOG4105E66	phosphoriboisomerase A
A3L11_05330	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3L11_05340	ENOG4105UQX	Mate efflux family protein
A3L11_05355	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A3L11_05380	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L11_05395	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L11_05405	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_05415	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L11_05425	ENOG4105C9B	Cysteine desulfurase
A3L11_05435	ENOG4105C45	hydrogenase expression formation protein (HypE)
A3L11_05445	ENOG4105CQS	hydrogenase expression formation protein HypD
A3L11_05455	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L11_05480	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L11_05515	ENOG4108IUZ	ABC transporter
A3L11_05525	ENOG4105CJ1	ABC, transporter
A3L11_05595	ENOG4107G87	m6 family metalloprotease domain protein
A3L11_05600	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L11_05620	ENOG4108Y83	glucose-6-phosphate isomerase
A3L11_05655	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L11_05690	ENOG4105CHM	Aminotransferase
A3L11_05715	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L11_05725	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3L11_05745	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L11_05755	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L11_05785	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L11_05855	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A3L11_05870	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L11_05875	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L11_05885	ENOG4107TE1	transport protein
A3L11_05915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3L11_05930	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A3L11_05935	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A3L11_05945	ENOG4105CX6	glutaminyL-tRNA synthetase
A3L11_05970	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L11_05990	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3L11_05995	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3L11_06010	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L11_06045	ENOG4108T9Q	UPF0278 protein
A3L11_06060	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3L11_06065	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A3L11_06080	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L11_06090	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L11_06145	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3L11_06195	ENOG4105CD5	CoA-binding domain protein
A3L11_06215	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A3L11_06255	ENOG4108VA3	3-hexulose-6-phosphate synthase
A3L11_06265	ENOG4107XGZ	Hydrolase
A3L11_06290	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L11_06305	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A3L11_06320	ENOG4105CH2	amidohydrolase
A3L11_06390	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3L11_06410	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_06425	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L11_06430	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L11_06440	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3L11_06445	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A3L11_06450	ENOG4108JJB	ABC transporter
A3L11_06475	ENOG4105CN9	Peptidase m42 family protein
A3L11_06490	ENOG4108Z0R	Transferase
A3L11_06495	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L11_06510	ENOG4105C22	threonyL-tRNA synthetase
A3L11_06570	ENOG4105F4G	Membrane
A3L11_06575	ENOG4105EEI	dihydropteroate synthase
A3L11_06600	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L11_06605	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3L11_06610	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3L11_06620	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3L11_06645	ENOG4105CPQ	Dehydrogenase
A3L11_06660	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3L11_06665	ENOG4105HDK	L-asparaginase
A3L11_06695	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3L11_06705	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L11_06745	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A3L11_06750	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A3L11_06825	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L11_06850	ENOG4105DBV	ornithine carbamoyltransferase
A3L11_06865	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A3L11_06885	ENOG4105E3H	phosphoglycerate mutase
A3L11_06890	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L11_06900	ENOG4108K7V	UPF0284 protein
A3L11_06920	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L11_06940	ENOG4105BZR	domain protein
A3L11_06995	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L11_07035	ENOG4105CHR	reductase
A3L11_07040	ENOG4108V1U	phospholipid-binding protein
A3L11_07080	ENOG4108JPW	Aminotransferase
A3L11_07105	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_07110	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L11_07115	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L11_07125	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L11_07130	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L11_07135	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L11_07140	ENOG4105D65	subunit l
A3L11_07150	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L11_07155	ENOG410684G	monovalent cation H antiporter subunit F
A3L11_07160	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L11_07170	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L11_07190	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3L11_07195	ENOG4108IJ1	Dehydrogenase
A3L11_07215	ENOG4105C75	arginyL-tRNA synthetase
A3L11_07225	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L11_07295	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3L11_07315	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L11_07325	ENOG4108VVK	transcriptional Regulator, AsnC
A3L11_07330	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A3L11_07335	ENOG4105YVS	arsR family transcriptional regulator
A3L11_07345	ENOG4105KME	endoribonuclease L-psp
A3L11_07355	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A3L11_07360	ENOG4105C3K	feS assembly ATPase SufC
A3L11_07365	ENOG4105DIW	FeS assembly protein SUFB
A3L11_07385	ENOG4107SHJ	sulfite reductase subunit b
A3L11_07400	ENOG4105CJ1	ABC, transporter
A3L11_07415	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A3L11_07460	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A3L11_07470	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A3L11_07480	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A3L11_07490	ENOG4105CHM	Aminotransferase
A3L11_07515	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L11_07520	ENOG4105C5I	Dehydrogenase
A3L11_07525	ENOG4105CN9	Peptidase m42 family protein
A3L11_07620	ENOG4105DQU	oxidoreductase, subunit beta
A3L11_07625	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L11_07645	ENOG4105DQU	oxidoreductase, subunit beta
A3L11_07650	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L11_07665	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A3L11_07670	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L11_07685	ENOG4105DIH	basic membrane
A3L11_07690	ENOG4108JQ9	ABC transporter
A3L11_07695	ENOG4105UIB	(ABC) transporter
A3L11_07715	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3L11_07720	ENOG4105C8N	cysteinyl-tRNA synthetase
A3L11_07725	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A3L11_07740	ENOG4107QN1	sodium solute
A3L11_07760	ENOG4107QRT	dEAD DEAH box helicase
A3L11_07760	ENOG4107QRT	dEAD DEAH box helicase
A3L11_07770	ENOG4107QJZ	Glycosyl transferase, family 2
A3L11_07775	ENOG4105CJ3	phosphate transporter
A3L11_07780	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A3L11_07845	ENOG4105DER	m42 family
A3L11_07880	ENOG4108WBT	adenosyltransferase
A3L11_07890	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L11_07905	ENOG4105CEV	competence damage-inducible protein
A3L11_07915	ENOG4105E0U	tyrosine-specific transport protein
A3L11_07920	ENOG4105VZ9	UPF0235 protein
A3L11_07935	ENOG4105VXP	Protein of unknown function DUF86
A3L11_07940	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A3L11_07960	ENOG4105UQX	Mate efflux family protein
A3L11_07980	ENOG4105FJR	Lmbe family
A3L11_07995	ENOG4105CS2	ec 3.2.1.21
A3L11_08000	ENOG4108J59	Extracellular solute-binding protein, family 5
A3L11_08005	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L11_08015	ENOG4105C3U	ABC transporter
A3L11_08020	ENOG4108JQ7	(ABC) transporter
A3L11_08025	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L11_08035	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L11_08050	ENOG4105DC7	peptidase M24
A3L11_08065	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A3L11_08110	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A3L11_08125	ENOG4105C3G	gtp-binding protein
A3L11_08140	ENOG4105D7N	magnesium and cobalt transport protein CorA
A3L11_08145	ENOG4105CG9	aspartate racemase
A3L11_08165	ENOG4105E4P	ATPase (AAA
A3L11_08200	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3L11_08205	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A3L11_08220	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A3L11_08225	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L11_08250	ENOG4105DCI	Phosphohydrolase
A3L11_08260	ENOG4105KNA	-acetyltransferase
A3L11_08265	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A3L11_08270	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A3L11_08295	ENOG4105E0R	Deoxyhypusine synthase
A3L11_08300	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A3L11_08305	ENOG4105D3W	isochorismatase
A3L11_08310	ENOG4105CAY	ferredoxin--nadp reductase
A3L11_08320	ENOG4105D0M	Protease HtpX homolog
A3L11_08325	ENOG4105D0M	Protease HtpX homolog
A3L11_08345	ENOG4105G0J	serine threonine protein kinase
A3L11_08350	ENOG4105C98	muts2 protein
A3L11_08360	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L11_08375	ENOG4108T0W	nitrous oxide maturation protein NosY
A3L11_08390	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L11_08410	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A3L11_08445	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A3L11_08450	ENOG4108I5C	dEAD DEAH box helicase
A3L11_08465	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3L11_08470	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L11_08540	ENOG4105FDK	ABC transporter
A3L11_08595	ENOG4105E4P	ATPase (AAA
A3L11_08610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L11_08615	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L11_08640	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3L11_08645	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3L11_08655	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3L11_08670	ENOG4105DCI	Phosphohydrolase
A3L11_08675	ENOG4105DA5	(ABC) transporter
A3L11_08715	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A3L11_08730	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A3L11_08770	ENOG4105FDK	ABC transporter
A3L11_08780	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3L11_08805	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L11_08820	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L11_08840	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A3L11_08855	ENOG4105CUB	amino acid
A3L11_08870	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L11_08915	ENOG4105WMR	Protein CrcB homolog
A3L11_08920	ENOG4105KJJ	Uncharacterized ACR, COG1993
A3L11_08925	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3L11_08935	ENOG4107QJE	Chromosome Partitioning Protein
A3L11_08975	ENOG41079KZ	Major Facilitator Superfamily
A3L11_08995	ENOG4105CIG	ABC transporter
A3L11_09020	ENOG4107XGZ	Hydrolase
A3L11_09030	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3L11_09065	ENOG4108J2R	molybdopterin oxidoreductase
A3L11_09070	ENOG4105D3R	alkyl hydroperoxide reductase
A3L11_09120	ENOG4108MK9	spermidine N(1)-acetyltransferase
A3L11_09145	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A3L11_09160	ENOG4105E0X	reductase
A3L11_09170	ENOG4105DQU	oxidoreductase, subunit beta
A3L11_09185	ENOG4105CNW	domain protein
A3L11_09195	ENOG4108RAC	Rubrerythrin
A3L11_09200	ENOG4105VCQ	rubredoxin
A3L11_09205	ENOG4108YZ8	Superoxide reductase
A3L11_09240	ENOG4105N80	Ferric uptake regulator, Fur family
A3L11_09270	ENOG4105CIG	ABC transporter
A3L11_09295	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A3L11_09320	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3L11_09325	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L11_09350	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L11_09360	ENOG4105CK2	sodium dicarboxylate symporter
A3L11_09365	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L11_09370	ENOG41061GT	Aldolase
A3L11_09375	ENOG4107QSA	Oxaloacetate decarboxylase
A3L11_09380	ENOG4105D22	carbon starvation protein
A3L11_09395	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A3L11_09420	ENOG4105E5G	Alpha beta hydrolase fold
A3L11_09440	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A3L11_09460	ENOG4107R21	site-determining protein
A3L11_09515	ENOG4105CHR	reductase
A3L11_09545	ENOG4105VYW	UPF0251 protein
A3L11_09550	ENOG4105C83	adenylosuccinate lyase
A3L11_09575	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L11_09600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A3L11_09605	ENOG4107QRT	dEAD DEAH box helicase
A3L11_09615	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L11_09620	ENOG4105C5X	domain protein
A3L11_09635	ENOG4105F8V	Hydrolase, tatD family
A3L11_09650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L11_09685	ENOG4107WZZ	SMC domain protein
A3L11_09685	ENOG4107WZZ	SMC domain protein
A3L11_09705	ENOG4105C5I	Dehydrogenase
A3L11_09710	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L11_09745	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A3L11_09775	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A3L11_09795	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L11_09800	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L11_09830	ENOG4105DP9	ABC transporter
A3L11_09850	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A3L11_09870	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A3L11_09885	ENOG4105VKD	bioY protein
A3L11_09890	ENOG4108JJB	ABC transporter
A3L11_09940	ENOG4105ECW	sulfate abc transporter
A3L11_09945	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L11_09970	ENOG4105BZA	Phosphoglycerate kinase
A3L11_10000	ENOG4105D5P	Methylmalonyl-coA mutase
A3L11_10020	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3L11_10035	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A3L11_10055	ENOG4105C1J	atp-dependent rna helicase
A3L11_10070	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A3L11_10085	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A3L11_10100	ENOG4107QMS	site-determining protein
A3L11_10105	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L11_10145	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A3L11_10155	ENOG4105E7W	lamb ycsf family protein
A3L11_10160	ENOG4105P4J	Allophanate hydrolase, subunit 1
A3L11_10175	ENOG4107QW4	alcohol dehydrogenase
A3L11_10185	ENOG4105ECY	inositol monophosphatase
A3L11_10200	ENOG4105DVT	helicase
A3L11_10215	ENOG4105CN9	Peptidase m42 family protein
A3L11_10230	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A3L11_10235	ENOG4107R8N	Glycosyl transferase, family 2
A3L11_10245	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3L11_10265	ENOG4108DBC	nitroreductase
A3L11_10275	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L11_10285	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L11_10295	ENOG4107RGD	Major Facilitator superfamily
A3L11_10300	ENOG4105CD5	CoA-binding domain protein
A3L11_10335	ENOG4105CSM	endonuclease III
A3L11_10345	ENOG4108Z03	MAF-like protein
A3L11_10365	ENOG4105CTP	PilT protein domain protein
A3L11_10370	ENOG4107QMS	site-determining protein
A3L11_10380	ENOG4105CAQ	asparagine synthetase
A3L11_10390	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L11_10395	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L11_10420	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3L11_10425	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L11_10450	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L11_10575	ENOG4107Y70	Heat shock protein
A3L11_10625	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A3L11_10630	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
A3L11_10640	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L11_10695	ENOG4108R6G	acetyltransferase
A3L11_10720	ENOG4105BZ1	(ABC) transporter
A3L11_10725	ENOG4105BZ1	(ABC) transporter
A3L11_10780	ENOG4105EAC	phosphoserine phosphatase
A3L11_10785	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A3L11_10805	ENOG4106IPI	cyclase, family
A3L11_10810	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A3L11_10835	ENOG4105C7R	Atpase associated with various cellular activities aaa_3