locus-tag	class	description
A3L11_00020	COG0434	BtpA family
A3L11_00050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L11_00055	COG1988	membrane-bound metal-dependent
A3L11_00070	COG0237	dephospho-CoA kinase activity
A3L11_00090	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L11_00095	COG0540	Belongs to the ATCase OTCase family
A3L11_00100	COG0351	phosphomethylpyrimidine kinase
A3L11_00100	COG1992	Thiamine-phosphate synthase
A3L11_00135	COG0442	prolyl-tRNA aminoacylation
A3L11_00140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L11_00150	COG2078	PFAM AMMECR1 domain protein
A3L11_00150	COG3885	ferrous iron binding
A3L11_00170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A3L11_00175	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L11_00180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L11_00190	COG1214	PFAM Peptidase M22, glycoprotease
A3L11_00190	COG0456	acetyltransferase
A3L11_00205	COG0156	8-amino-7-oxononanoate synthase activity
A3L11_00215	COG2255	four-way junction helicase activity
A3L11_00220	COG2255	four-way junction helicase activity
A3L11_00225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A3L11_00240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L11_00270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L11_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3L11_00335	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L11_00340	COG0402	S-adenosylhomocysteine deaminase activity
A3L11_00360	COG1446	asparaginase
A3L11_00365	COG2814	Major facilitator Superfamily
A3L11_00370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L11_00385	COG2271	Major facilitator Superfamily
A3L11_00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L11_00420	COG2131	deaminase
A3L11_00425	COG0501	Belongs to the peptidase M48B family
A3L11_00460	COG0543	2 iron, 2 sulfur cluster binding
A3L11_00465	COG0493	'glutamate synthase
A3L11_00465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L11_00480	COG1028	Short-chain dehydrogenase reductase Sdr
A3L11_00490	COG1141	Ferredoxin
A3L11_00495	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L11_00530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L11_00535	COG0167	dihydroorotate dehydrogenase activity
A3L11_00560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L11_00620	COG2814	Major facilitator Superfamily
A3L11_00630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L11_00645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L11_00670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_00675	COG1522	sequence-specific DNA binding
A3L11_00700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A3L11_00705	COG2095	MarC family integral membrane protein
A3L11_00710	COG1765	OsmC-like protein
A3L11_00720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L11_00725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L11_00730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L11_00790	COG0123	including yeast histone deacetylase and acetoin utilization protein
A3L11_00830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L11_00855	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L11_00880	COG0651	ATP synthesis coupled electron transport
A3L11_00910	COG2212	antiporter activity
A3L11_00915	COG1863	multisubunit Na H antiporter MnhE subunit
A3L11_00920	COG0509	glycine decarboxylation via glycine cleavage system
A3L11_00925	COG0438	transferase activity, transferring glycosyl groups
A3L11_00930	COG0493	'glutamate synthase
A3L11_00930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L11_00935	COG0543	2 iron, 2 sulfur cluster binding
A3L11_00965	COG0747	negative chemotaxis
A3L11_00970	COG0601	transmembrane transport
A3L11_00980	COG0444	Belongs to the ABC transporter superfamily
A3L11_00985	COG4608	Belongs to the ABC transporter superfamily
A3L11_01020	COG1131	(ABC) transporter
A3L11_01025	COG1476	TRANSCRIPTIONal
A3L11_01070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L11_01075	COG1192	Involved in chromosome partitioning
A3L11_01085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L11_01085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L11_01095	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L11_01110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L11_01110	COG1213	nucleotidyl transferase
A3L11_01135	COG1131	(ABC) transporter
A3L11_01180	COG1850	ribulose-bisphosphate carboxylase activity
A3L11_01185	COG1435	thymidine kinase activity
A3L11_01190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L11_01230	COG0463	Glycosyl transferase, family 2
A3L11_01260	COG3842	ATPase activity
A3L11_01270	COG2379	hydroxypyruvate reductase
A3L11_01300	COG1832	CoA-binding protein
A3L11_01330	COG0432	Pfam Uncharacterised protein family UPF0047
A3L11_01335	COG1160	GTP binding
A3L11_01350	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L11_01355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3L11_01360	COG3842	ATPase activity
A3L11_01370	COG0714	Associated with various cellular activities
A3L11_01405	COG0312	modulator of DNA gyrase
A3L11_01420	COG0312	modulator of DNA gyrase
A3L11_01440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L11_01465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L11_01475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L11_01480	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A3L11_01485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L11_01515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L11_01525	COG0306	phosphate transporter
A3L11_01540	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L11_01545	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_01555	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L11_01560	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_01570	COG0437	4 iron, 4 sulfur cluster binding
A3L11_01575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L11_01575	COG0493	'glutamate synthase
A3L11_01585	COG1151	hydroxylamine reductase activity
A3L11_01590	COG0437	4 iron, 4 sulfur cluster binding
A3L11_01610	COG4139	cobalamin transport
A3L11_01615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L11_01620	COG0489	protein tyrosine kinase activity
A3L11_01645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L11_01655	COG1254	Belongs to the acylphosphatase family
A3L11_01665	COG1628	Protein of unknown function DUF99
A3L11_01670	COG0589	response to stress
A3L11_01770	COG1233	COG1233 Phytoene dehydrogenase and related
A3L11_01790	COG1980	fructose-bisphosphate aldolase activity
A3L11_01810	COG1522	sequence-specific DNA binding
A3L11_01825	COG2894	cell division
A3L11_01830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3L11_01865	COG1757	Na H antiporter
A3L11_01870	COG1573	uracil-dna glycosylase
A3L11_01880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L11_01895	COG1380	Effector of murein hydrolase LrgA
A3L11_01900	COG1346	cytolysis
A3L11_01930	COG0235	Class ii aldolase
A3L11_01940	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A3L11_02015	COG0095	Lipoate-protein ligase
A3L11_02020	COG0681	Belongs to the peptidase S26 family
A3L11_02070	COG0823	Involved in the tonB-independent uptake of proteins
A3L11_02070	COG4946	Tricorn protease homolog
A3L11_02070	COG1506	peptidase
A3L11_02095	COG0306	phosphate transporter
A3L11_02125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L11_02135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L11_02145	COG2212	antiporter activity
A3L11_02150	COG1320	monovalent cation:proton antiporter activity
A3L11_02170	COG0713	ATP synthesis coupled electron transport
A3L11_02175	COG0651	ATP synthesis coupled electron transport
A3L11_02185	COG3260	NADH ubiquinone oxidoreductase 20
A3L11_02190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_02200	COG0650	Formate hydrogenlyase subunit 4
A3L11_02205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_02215	COG2212	antiporter activity
A3L11_02220	COG1320	monovalent cation:proton antiporter activity
A3L11_02235	COG2111	Na H antiporter
A3L11_02240	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L11_02245	COG0651	ATP synthesis coupled electron transport
A3L11_02255	COG3260	NADH ubiquinone oxidoreductase 20
A3L11_02260	COG0649	NAD binding
A3L11_02260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_02270	COG0650	Formate hydrogenlyase subunit 4
A3L11_02275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_02300	COG2255	four-way junction helicase activity
A3L11_02320	COG0492	ferredoxin-NADP+ reductase activity
A3L11_02335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L11_02365	COG0148	phosphopyruvate hydratase activity
A3L11_02395	COG1522	sequence-specific DNA binding
A3L11_02420	COG0314	molybdopterin synthase activity
A3L11_02430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L11_02470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L11_02470	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L11_02485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L11_02495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L11_02515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L11_02515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L11_02565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L11_02590	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L11_02605	COG0402	S-adenosylhomocysteine deaminase activity
A3L11_02610	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L11_02610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L11_02625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L11_02625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L11_02690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L11_02700	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L11_02720	COG0116	Belongs to the methyltransferase superfamily
A3L11_02720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L11_02725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3L11_02760	COG1047	Peptidyl-prolyl cis-trans
A3L11_02785	COG0714	Associated with various cellular activities
A3L11_02805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L11_02825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L11_02830	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A3L11_02855	COG1373	ATPase (AAA superfamily
A3L11_02860	COG0037	tRNA processing
A3L11_02865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L11_02870	COG0463	Glycosyl transferase, family 2
A3L11_02870	COG1216	Glycosyl transferase, family 2
A3L11_02900	COG0730	response to heat
A3L11_02930	COG2046	Belongs to the sulfate adenylyltransferase family
A3L11_02940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L11_02950	COG0475	glutathione-regulated potassium exporter activity
A3L11_02975	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L11_02990	COG0037	tRNA processing
A3L11_02995	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L11_03000	COG0517	IMP dehydrogenase activity
A3L11_03000	COG0516	GMP reductase activity
A3L11_03005	COG0475	glutathione-regulated potassium exporter activity
A3L11_03010	COG0475	glutathione-regulated potassium exporter activity
A3L11_03040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L11_03050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L11_03095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L11_03105	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L11_03120	COG0569	domain protein
A3L11_03130	COG1269	ATP hydrolysis coupled proton transport
A3L11_03140	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L11_03150	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L11_03155	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L11_03160	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
A3L11_03165	COG1394	ATPase activity, coupled to movement of substances
A3L11_03170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L11_03175	COG0482	sulfurtransferase activity
A3L11_03195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3L11_03205	COG0601	transmembrane transport
A3L11_03210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L11_03215	COG0444	Belongs to the ABC transporter superfamily
A3L11_03220	COG4608	Belongs to the ABC transporter superfamily
A3L11_03240	COG0174	glutamine synthetase
A3L11_03280	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L11_03300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L11_03320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L11_03330	COG1297	OPT oligopeptide transporter protein
A3L11_03335	COG1234	tRNA 3'-trailer cleavage
A3L11_03340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L11_03350	COG3842	ATPase activity
A3L11_03360	COG3833	ABC-type maltose transport systems, permease component
A3L11_03365	COG1175	transmembrane transport
A3L11_03380	COG1378	Sugar-specific transcriptional regulator TrmB
A3L11_03385	COG0297	glycogen (starch) synthase activity
A3L11_03425	COG0697	spore germination
A3L11_03445	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L11_03465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L11_03475	COG0647	UMP catabolic process
A3L11_03495	COG0463	Glycosyl transferase, family 2
A3L11_03500	COG0438	transferase activity, transferring glycosyl groups
A3L11_03525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3L11_03540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3L11_03565	COG0714	Associated with various cellular activities
A3L11_03630	COG1091	dTDP-4-dehydrorhamnose reductase activity
A3L11_03650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L11_03660	COG0463	Glycosyl transferase, family 2
A3L11_03670	COG1216	Glycosyl transferase, family 2
A3L11_03680	COG1215	transferase activity, transferring glycosyl groups
A3L11_03685	COG1216	Glycosyl transferase, family 2
A3L11_03765	COG0517	IMP dehydrogenase activity
A3L11_03765	COG0516	GMP reductase activity
A3L11_03775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L11_03780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L11_03790	COG0157	Belongs to the NadC ModD family
A3L11_03795	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3L11_03800	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3L11_03805	COG3383	formate dehydrogenase (NAD+) activity
A3L11_03810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L11_03815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L11_03820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L11_03825	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L11_03830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L11_03835	COG0151	Belongs to the GarS family
A3L11_03855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L11_03865	COG0519	Catalyzes the synthesis of GMP from XMP
A3L11_03865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L11_03880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L11_03880	COG0519	Catalyzes the synthesis of GMP from XMP
A3L11_03945	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L11_03970	COG0539	negative regulation of cytoplasmic translation
A3L11_04035	COG0463	Glycosyl transferase, family 2
A3L11_04040	COG2234	aminopeptidase activity
A3L11_04120	COG0393	Putative heavy-metal-binding
A3L11_04145	COG2264	protein methyltransferase activity
A3L11_04160	COG0668	transmembrane transport
A3L11_04230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L11_04235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L11_04300	COG1178	ABC-type Fe3 transport system permease component
A3L11_04325	COG0011	TIGRFAM Protein of
A3L11_04330	COG2078	PFAM AMMECR1 domain protein
A3L11_04345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L11_04345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L11_04365	COG0417	DNA replication proofreading
A3L11_04410	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L11_04435	COG1695	Transcriptional regulator
A3L11_04440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L11_04440	COG2050	protein possibly involved in aromatic compounds catabolism
A3L11_04450	COG1335	isochorismatase
A3L11_04490	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_04530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L11_04545	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L11_04550	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L11_04585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L11_04585	COG0517	IMP dehydrogenase activity
A3L11_04590	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L11_04595	COG5016	pyruvate
A3L11_04595	COG0511	ligase activity, forming carbon-carbon bonds
A3L11_04605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L11_04615	COG0305	Participates in initiation and elongation during chromosome replication
A3L11_04615	COG1372	Participates in initiation and elongation during chromosome replication
A3L11_04640	COG0430	RNA-3'-phosphate cyclase activity
A3L11_04675	COG3259	Nickel-dependent hydrogenase
A3L11_04685	COG0543	2 iron, 2 sulfur cluster binding
A3L11_04715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L11_04735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L11_04780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L11_04790	COG0089	rRNA binding
A3L11_04795	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L11_04800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L11_04810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L11_04815	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L11_04820	COG0023	Translation Initiation Factor
A3L11_04830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L11_04835	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L11_04840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L11_04850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L11_04860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L11_04865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3L11_04880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L11_04885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L11_04890	COG1841	ribosomal large subunit assembly
A3L11_04895	COG0200	Binds to the 23S rRNA
A3L11_04920	COG1102	Psort location Cytoplasmic, score
A3L11_04935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L11_04940	COG2813	Specifically methylates the guanine in position
A3L11_04950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L11_04955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L11_04980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L11_04985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L11_05010	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L11_05045	COG1522	sequence-specific DNA binding
A3L11_05055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L11_05070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L11_05085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L11_05090	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L11_05105	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L11_05115	COG1355	regulation of microtubule-based process
A3L11_05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L11_05145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L11_05150	COG2414	aldehyde ferredoxin oxidoreductase
A3L11_05155	COG1304	FMN binding
A3L11_05170	COG0142	geranyltranstransferase activity
A3L11_05175	COG0477	Major facilitator Superfamily
A3L11_05190	COG0495	leucyl-tRNA aminoacylation
A3L11_05205	COG0006	proline dipeptidase activity
A3L11_05250	COG0864	Transcriptional regulator
A3L11_05265	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L11_05270	COG0347	Belongs to the P(II) protein family
A3L11_05280	COG0733	neurotransmitter:sodium symporter activity
A3L11_05285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L11_05300	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L11_05305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L11_05320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3L11_05330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L11_05340	COG0534	Mate efflux family protein
A3L11_05355	COG0574	Belongs to the PEP-utilizing enzyme family
A3L11_05355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L11_05380	COG1404	Belongs to the peptidase S8 family
A3L11_05395	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L11_05405	COG0731	radical SAM domain protein
A3L11_05405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_05415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L11_05425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L11_05440	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L11_05445	COG0409	Hydrogenase expression formation protein
A3L11_05450	COG0298	carbon dioxide binding
A3L11_05455	COG0746	molybdenum cofactor guanylyltransferase activity
A3L11_05470	COG0489	protein tyrosine kinase activity
A3L11_05480	COG2414	aldehyde ferredoxin oxidoreductase
A3L11_05515	COG1137	ATPase activity
A3L11_05520	COG0719	Fe-S assembly protein
A3L11_05520	COG1372	Participates in initiation and elongation during chromosome replication
A3L11_05525	COG1131	(ABC) transporter
A3L11_05595	COG3291	Pkd domain containing protein
A3L11_05595	COG4412	M6 family metalloprotease domain protein
A3L11_05600	COG1234	tRNA 3'-trailer cleavage
A3L11_05620	COG2140	Oxalate decarboxylase
A3L11_05655	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L11_05690	COG0436	Aminotransferase
A3L11_05725	COG0049	tRNA binding
A3L11_05745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L11_05750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L11_05755	COG0085	RNA polymerase activity
A3L11_05785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L11_05850	COG0579	oxidoreductase
A3L11_05870	COG0584	glycerophosphoryl diester phosphodiesterase
A3L11_05875	COG0584	glycerophosphoryl diester phosphodiesterase
A3L11_05880	COG2211	Major facilitator Superfamily
A3L11_05885	COG2271	Major facilitator Superfamily
A3L11_05890	COG0429	hydrolase of the alpha beta-hydrolase fold
A3L11_05915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L11_05935	COG0058	SHG alpha-glucan phosphorylase activity
A3L11_05945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L11_05970	COG0717	Belongs to the dCTP deaminase family
A3L11_05990	COG0081	regulation of translation
A3L11_05995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L11_06010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L11_06060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L11_06065	COG0644	oxidoreductase
A3L11_06090	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L11_06145	COG1518	maintenance of DNA repeat elements
A3L11_06215	COG1110	DNA topoisomerase II activity
A3L11_06255	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L11_06265	COG0546	phosphoglycolate phosphatase activity
A3L11_06280	COG1418	mRNA catabolic process
A3L11_06290	COG0017	Asparaginyl-tRNA synthetase
A3L11_06305	COG0585	pseudouridine synthase activity
A3L11_06320	COG1473	amidohydrolase
A3L11_06390	COG0504	CTP synthase activity
A3L11_06410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L11_06440	COG0024	Methionine aminopeptidase
A3L11_06445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L11_06450	COG1122	ATPase activity
A3L11_06495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L11_06510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L11_06570	COG0628	permease
A3L11_06575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L11_06595	COG1131	(ABC) transporter
A3L11_06605	COG0556	nucleotide-excision repair
A3L11_06610	COG0101	tRNA pseudouridine synthase activity
A3L11_06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3L11_06640	COG2886	Uncharacterised protein family (UPF0175)
A3L11_06645	COG1063	alcohol dehydrogenase
A3L11_06650	COG2894	cell division
A3L11_06660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L11_06665	COG0252	asparaginase activity
A3L11_06695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L11_06705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L11_06745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L11_06750	COG1085	galactose-1-phosphate uridylyltransferase
A3L11_06775	COG0475	glutathione-regulated potassium exporter activity
A3L11_06790	COG0010	Belongs to the arginase family
A3L11_06850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L11_06865	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L11_06885	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L11_06890	COG1573	uracil-dna glycosylase
A3L11_06920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L11_06920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L11_06940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3L11_06940	COG0359	binds to the 23S rRNA
A3L11_06995	COG0602	queuosine metabolic process
A3L11_07000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L11_07035	COG1028	Short-chain dehydrogenase reductase Sdr
A3L11_07040	COG1881	PFAM PEBP family protein
A3L11_07105	COG0649	NAD binding
A3L11_07110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_07115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L11_07125	COG0651	ATP synthesis coupled electron transport
A3L11_07130	COG0651	ATP synthesis coupled electron transport
A3L11_07135	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L11_07140	COG2111	Na H antiporter
A3L11_07140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L11_07150	COG1320	monovalent cation:proton antiporter activity
A3L11_07155	COG2212	antiporter activity
A3L11_07160	COG1863	multisubunit Na H antiporter MnhE subunit
A3L11_07170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L11_07195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L11_07215	COG0018	arginyl-trna synthetase
A3L11_07225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L11_07320	COG1836	PFAM Integral membrane protein DUF92
A3L11_07325	COG1522	sequence-specific DNA binding
A3L11_07330	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L11_07335	COG0640	Transcriptional regulator
A3L11_07360	COG0396	ATPase activity
A3L11_07365	COG0719	Fe-S assembly protein
A3L11_07380	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
A3L11_07400	COG1131	(ABC) transporter
A3L11_07415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L11_07425	COG1476	TRANSCRIPTIONal
A3L11_07460	COG1515	deoxyribonuclease V activity
A3L11_07470	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L11_07480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L11_07490	COG0436	Aminotransferase
A3L11_07505	COG2192	nodulation
A3L11_07515	COG0442	prolyl-tRNA aminoacylation
A3L11_07520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L11_07540	COG0730	response to heat
A3L11_07550	COG0730	response to heat
A3L11_07620	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_07625	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L11_07625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L11_07645	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_07650	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L11_07650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L11_07665	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L11_07670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L11_07685	COG1744	ABC transporter substrate-binding protein PnrA-like
A3L11_07720	COG0215	cysteine-tRNA ligase activity
A3L11_07725	COG1047	Peptidyl-prolyl cis-trans
A3L11_07740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L11_07750	COG1505	serine-type exopeptidase activity
A3L11_07760	COG1201	RNA secondary structure unwinding
A3L11_07760	COG1201	RNA secondary structure unwinding
A3L11_07775	COG0306	phosphate transporter
A3L11_07780	COG0343	queuine tRNA-ribosyltransferase activity
A3L11_07845	COG1363	Peptidase, m42
A3L11_07880	COG2096	Adenosyltransferase
A3L11_07890	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L11_07905	COG1546	Belongs to the CinA family
A3L11_07905	COG1058	Belongs to the CinA family
A3L11_07915	COG0814	amino acid
A3L11_07920	COG1872	DUF167
A3L11_07935	COG2361	Protein of unknown function DUF86
A3L11_07940	COG0423	glycine-tRNA ligase activity
A3L11_07960	COG0534	Mate efflux family protein
A3L11_07995	COG2723	6-phospho-beta-galactosidase activity
A3L11_08000	COG4166	transmembrane transport
A3L11_08005	COG0601	transmembrane transport
A3L11_08015	COG0444	Belongs to the ABC transporter superfamily
A3L11_08020	COG4608	Belongs to the ABC transporter superfamily
A3L11_08025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L11_08035	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L11_08050	COG0006	proline dipeptidase activity
A3L11_08065	COG0482	sulfurtransferase activity
A3L11_08090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L11_08110	COG0163	prenyltransferase activity
A3L11_08125	COG0012	GTP binding
A3L11_08140	COG0598	Magnesium transport protein CorA
A3L11_08145	COG1794	racemase activity, acting on amino acids and derivatives
A3L11_08155	COG0312	modulator of DNA gyrase
A3L11_08165	COG1373	ATPase (AAA superfamily
A3L11_08175	COG1525	nuclease
A3L11_08200	COG0525	valine-tRNA ligase activity
A3L11_08205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L11_08220	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3L11_08225	COG0303	'Molybdopterin
A3L11_08250	COG1078	dGTPase activity
A3L11_08265	COG3103	Sh3 type 3 domain protein
A3L11_08265	COG0366	Alpha amylase catalytic
A3L11_08270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A3L11_08295	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L11_08300	COG1028	Short-chain dehydrogenase reductase Sdr
A3L11_08305	COG1335	isochorismatase
A3L11_08310	COG0492	ferredoxin-NADP+ reductase activity
A3L11_08320	COG0501	Belongs to the peptidase M48B family
A3L11_08335	COG0459	protein refolding
A3L11_08345	COG0515	serine threonine protein kinase
A3L11_08350	COG1193	negative regulation of DNA recombination
A3L11_08360	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L11_08365	COG1131	(ABC) transporter
A3L11_08375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A3L11_08390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L11_08390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L11_08410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A3L11_08415	COG1215	transferase activity, transferring glycosyl groups
A3L11_08445	COG1739	Uncharacterized protein family UPF0029
A3L11_08450	COG1111	helicase
A3L11_08450	COG1205	dead DEAH box helicase
A3L11_08465	COG1518	maintenance of DNA repeat elements
A3L11_08470	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L11_08540	COG1121	(ABC) transporter
A3L11_08580	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L11_08595	COG1373	ATPase (AAA superfamily
A3L11_08610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L11_08615	COG2414	aldehyde ferredoxin oxidoreductase
A3L11_08640	COG0051	transcription antitermination factor activity, RNA binding
A3L11_08645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L11_08655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L11_08670	COG1078	dGTPase activity
A3L11_08675	COG1131	(ABC) transporter
A3L11_08715	COG1469	GTP cyclohydrolase I activity
A3L11_08730	COG1401	restriction endodeoxyribonuclease activity
A3L11_08770	COG1121	(ABC) transporter
A3L11_08780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3L11_08805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L11_08820	COG2226	methyltransferase
A3L11_08825	COG0011	TIGRFAM Protein of
A3L11_08840	COG0563	adenylate kinase activity
A3L11_08855	COG0531	amino acid
A3L11_08870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L11_08915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L11_08920	COG1993	acr, cog1993
A3L11_08930	COG0668	transmembrane transport
A3L11_08935	COG1192	Involved in chromosome partitioning
A3L11_08940	COG1794	racemase activity, acting on amino acids and derivatives
A3L11_08975	COG0477	Major facilitator Superfamily
A3L11_09020	COG0546	phosphoglycolate phosphatase activity
A3L11_09030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L11_09065	COG0243	molybdopterin cofactor binding
A3L11_09070	COG0450	alkyl hydroperoxide reductase
A3L11_09120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L11_09145	COG0425	Belongs to the sulfur carrier protein TusA family
A3L11_09160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L11_09160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L11_09170	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L11_09185	COG0426	domain, Protein
A3L11_09195	COG1592	Rubrerythrin
A3L11_09200	COG1773	rubredoxin
A3L11_09205	COG2033	superoxide reductase activity
A3L11_09240	COG0735	belongs to the Fur family
A3L11_09295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L11_09320	COG1518	maintenance of DNA repeat elements
A3L11_09325	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L11_09350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L11_09360	COG1301	dicarboxylic acid transport
A3L11_09365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3L11_09365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3L11_09370	COG1830	Aldolase
A3L11_09380	COG1966	Carbon starvation protein
A3L11_09395	COG0003	Pfam Anion-transporting ATPase
A3L11_09420	COG2267	carboxylic ester hydrolase activity
A3L11_09440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A3L11_09460	COG0455	bacterial-type flagellum organization
A3L11_09465	COG0489	protein tyrosine kinase activity
A3L11_09545	COG1342	Belongs to the UPF0251 family
A3L11_09550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L11_09575	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L11_09600	COG0477	Major facilitator Superfamily
A3L11_09605	COG1201	RNA secondary structure unwinding
A3L11_09615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L11_09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L11_09635	COG0084	hydrolase, TatD family'
A3L11_09650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L11_09685	COG0419	ATPase involved in DNA repair
A3L11_09685	COG0419	ATPase involved in DNA repair
A3L11_09705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L11_09745	COG0105	UTP biosynthetic process
A3L11_09775	COG0175	sulfate reduction
A3L11_09795	COG0402	S-adenosylhomocysteine deaminase activity
A3L11_09800	COG0017	Asparaginyl-tRNA synthetase
A3L11_09830	COG4143	(ABC) transporter
A3L11_09850	COG1444	tRNA N-acetyltransferase activity
A3L11_09870	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
A3L11_09885	COG1268	BioY protein
A3L11_09890	COG1122	ATPase activity
A3L11_09920	COG1522	sequence-specific DNA binding
A3L11_09940	COG4208	sulfate ABC transporter
A3L11_09945	COG3842	ATPase activity
A3L11_09970	COG0126	phosphoglycerate kinase activity
A3L11_10000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L11_10000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L11_10020	COG1196	nuclear chromosome segregation
A3L11_10035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L11_10055	COG0513	Belongs to the DEAD box helicase family
A3L11_10070	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L11_10085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L11_10100	COG2894	cell division
A3L11_10105	COG0330	HflC and HflK could
A3L11_10120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3L11_10145	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L11_10145	COG2247	cell wall binding repeat
A3L11_10150	COG4956	integral membrane protein (PIN domain superfamily)
A3L11_10155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L11_10160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L11_10165	COG1984	allophanate hydrolase subunit 2
A3L11_10175	COG1979	alcohol dehydrogenase
A3L11_10185	COG0483	inositol monophosphate 1-phosphatase activity
A3L11_10200	COG1199	ATP-dependent helicase activity
A3L11_10230	COG1489	DNA binding
A3L11_10235	COG1215	transferase activity, transferring glycosyl groups
A3L11_10265	COG0778	Nitroreductase
A3L11_10275	COG0301	tRNA thio-modification
A3L11_10285	COG0301	tRNA thio-modification
A3L11_10300	COG1042	CoA-binding domain protein
A3L11_10300	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L11_10300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L11_10335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L11_10365	COG4956	integral membrane protein (PIN domain superfamily)
A3L11_10370	COG2894	cell division
A3L11_10380	COG0367	asparagine synthase
A3L11_10390	COG0438	transferase activity, transferring glycosyl groups
A3L11_10395	COG0009	L-threonylcarbamoyladenylate synthase
A3L11_10420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L11_10425	COG0303	'Molybdopterin
A3L11_10450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L11_10575	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L11_10625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L11_10630	COG0778	Nitroreductase
A3L11_10695	COG0456	acetyltransferase
A3L11_10720	COG1132	(ABC) transporter
A3L11_10725	COG1132	(ABC) transporter
A3L11_10730	COG1051	belongs to the nudix hydrolase family
A3L11_10730	COG1056	cytidyltransferase-related domain
A3L11_10780	COG0560	Phosphoserine phosphatase
A3L11_10785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L11_10805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L11_10810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L11_10835	COG0714	Associated with various cellular activities