locus-tag	class	description
ADU37_CDS00050	COG1346	cytolysis
ADU37_CDS00090	COG1067	ATP-dependent peptidase activity
ADU37_CDS00090	COG0470	DNA polymerase III
ADU37_CDS00110	COG1215	transferase activity, transferring glycosyl groups
ADU37_CDS00120	COG0343	queuine tRNA-ribosyltransferase activity
ADU37_CDS00160	COG0433	COG0433 Predicted ATPase
ADU37_CDS00170	COG0366	Alpha amylase catalytic
ADU37_CDS00180	COG0456	acetyltransferase
ADU37_CDS00210	COG0156	8-amino-7-oxononanoate synthase activity
ADU37_CDS00220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADU37_CDS00230	COG2255	four-way junction helicase activity
ADU37_CDS00260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU37_CDS00300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADU37_CDS00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADU37_CDS00390	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ADU37_CDS00400	COG2226	methyltransferase
ADU37_CDS00440	COG0281	malic enzyme
ADU37_CDS00480	COG2151	metal-sulfur cluster biosynthetic enzyme
ADU37_CDS00490	COG1141	Ferredoxin
ADU37_CDS00570	COG0730	response to heat
ADU37_CDS00580	COG1363	Peptidase, m42
ADU37_CDS00660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADU37_CDS00740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADU37_CDS00750	COG2239	Acts as a magnesium transporter
ADU37_CDS00770	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
ADU37_CDS00780	COG0725	ABC transporter, periplasmic molybdate-binding protein
ADU37_CDS00790	COG4149	molybdate abc transporter
ADU37_CDS00800	COG3842	ATPase activity
ADU37_CDS00830	COG1201	RNA secondary structure unwinding
ADU37_CDS00860	COG1505	serine-type exopeptidase activity
ADU37_CDS00870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADU37_CDS00900	COG1047	Peptidyl-prolyl cis-trans
ADU37_CDS00950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU37_CDS01050	COG0803	Belongs to the bacterial solute-binding protein 9 family
ADU37_CDS01090	COG1744	ABC transporter substrate-binding protein PnrA-like
ADU37_CDS01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADU37_CDS01180	COG0237	dephospho-CoA kinase activity
ADU37_CDS01250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADU37_CDS01310	COG0432	Pfam Uncharacterised protein family UPF0047
ADU37_CDS01350	COG4555	ABC transporter
ADU37_CDS01460	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU37_CDS01460	COG1042	CoA-binding domain protein
ADU37_CDS01460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADU37_CDS01490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADU37_CDS01510	COG1695	Transcriptional regulator
ADU37_CDS01540	COG0126	phosphoglycerate kinase activity
ADU37_CDS01550	COG1715	Restriction endonuclease
ADU37_CDS01590	COG3842	ATPase activity
ADU37_CDS01610	COG1178	ABC-type Fe3 transport system permease component
ADU37_CDS01660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADU37_CDS01680	COG1301	dicarboxylic acid transport
ADU37_CDS01690	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ADU37_CDS01690	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ADU37_CDS01700	COG1830	Aldolase
ADU37_CDS01720	COG1966	Carbon starvation protein
ADU37_CDS01790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADU37_CDS01790	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ADU37_CDS01820	COG1748	Saccharopine dehydrogenase
ADU37_CDS01850	COG0010	Belongs to the arginase family
ADU37_CDS01870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADU37_CDS01890	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ADU37_CDS01890	COG0662	Cupin 2, conserved barrel domain protein
ADU37_CDS01900	COG3769	mannosylglycerate metabolic process
ADU37_CDS01930	COG1793	dna ligase
ADU37_CDS01930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ADU37_CDS01940	COG0509	glycine decarboxylation via glycine cleavage system
ADU37_CDS01970	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADU37_CDS02030	COG1473	amidohydrolase
ADU37_CDS02060	COG0574	Belongs to the PEP-utilizing enzyme family
ADU37_CDS02060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADU37_CDS02070	COG0534	Mate efflux family protein
ADU37_CDS02090	COG1446	asparaginase
ADU37_CDS02100	COG2814	Major facilitator Superfamily
ADU37_CDS02140	COG2814	Major facilitator Superfamily
ADU37_CDS02170	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
ADU37_CDS02210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADU37_CDS02220	COG0088	Forms part of the polypeptide exit tunnel
ADU37_CDS02230	COG0089	rRNA binding
ADU37_CDS02240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADU37_CDS02250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADU37_CDS02260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADU37_CDS02270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADU37_CDS02280	COG0255	Belongs to the universal ribosomal protein uL29 family
ADU37_CDS02310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADU37_CDS02320	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADU37_CDS02330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADU37_CDS02350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADU37_CDS02370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADU37_CDS02380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADU37_CDS02410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADU37_CDS02440	COG0200	Binds to the 23S rRNA
ADU37_CDS02490	COG1102	Psort location Cytoplasmic, score
ADU37_CDS02520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU37_CDS02560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADU37_CDS02620	COG2813	Specifically methylates the guanine in position
ADU37_CDS02630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADU37_CDS02640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADU37_CDS02680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADU37_CDS02690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADU37_CDS02720	COG0148	phosphopyruvate hydratase activity
ADU37_CDS02730	COG0052	Belongs to the universal ribosomal protein uS2 family
ADU37_CDS02750	COG0301	tRNA thio-modification
ADU37_CDS02770	COG0301	tRNA thio-modification
ADU37_CDS02790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADU37_CDS02870	COG3842	ATPase activity
ADU37_CDS02910	COG1178	ABC-type Fe3 transport system permease component
ADU37_CDS02930	COG4143	(ABC) transporter
ADU37_CDS03010	COG0434	BtpA family
ADU37_CDS03090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADU37_CDS03120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADU37_CDS03130	COG0081	regulation of translation
ADU37_CDS03160	COG0717	Belongs to the dCTP deaminase family
ADU37_CDS03180	COG0085	RNA polymerase activity
ADU37_CDS03190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADU37_CDS03200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADU37_CDS03240	COG0049	tRNA binding
ADU37_CDS03250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADU37_CDS03270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADU37_CDS03280	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ADU37_CDS03380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADU37_CDS03390	COG2095	MarC family integral membrane protein
ADU37_CDS03460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADU37_CDS03570	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ADU37_CDS03620	COG1418	mRNA catabolic process
ADU37_CDS03640	COG0017	Asparaginyl-tRNA synthetase
ADU37_CDS03670	COG0585	pseudouridine synthase activity
ADU37_CDS03710	COG0543	2 iron, 2 sulfur cluster binding
ADU37_CDS03720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADU37_CDS03730	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ADU37_CDS03740	COG0540	Belongs to the ATCase OTCase family
ADU37_CDS03750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADU37_CDS03770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU37_CDS03780	COG1522	sequence-specific DNA binding
ADU37_CDS03800	COG0475	glutathione-regulated potassium exporter activity
ADU37_CDS03810	COG0475	glutathione-regulated potassium exporter activity
ADU37_CDS03820	COG0517	IMP dehydrogenase activity
ADU37_CDS03820	COG0516	GMP reductase activity
ADU37_CDS03830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ADU37_CDS03840	COG0037	tRNA processing
ADU37_CDS03850	COG1449	Belongs to the glycosyl hydrolase 57 family
ADU37_CDS03940	COG0351	phosphomethylpyrimidine kinase
ADU37_CDS03960	COG0352	thiamine-phosphate diphosphorylase activity
ADU37_CDS03970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ADU37_CDS03990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADU37_CDS03990	COG0116	Belongs to the methyltransferase superfamily
ADU37_CDS04020	COG1058	Belongs to the CinA family
ADU37_CDS04020	COG1546	Belongs to the CinA family
ADU37_CDS04030	COG0469	pyruvate kinase activity
ADU37_CDS04070	COG2414	aldehyde ferredoxin oxidoreductase
ADU37_CDS04150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADU37_CDS04160	COG1993	acr, cog1993
ADU37_CDS04280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADU37_CDS04300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADU37_CDS04310	COG1185	polyribonucleotide nucleotidyltransferase activity
ADU37_CDS04360	COG0616	signal peptide processing
ADU37_CDS04410	COG1918	ferrous iron import across plasma membrane
ADU37_CDS04410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADU37_CDS04430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ADU37_CDS04450	COG0163	prenyltransferase activity
ADU37_CDS04460	COG1522	sequence-specific DNA binding
ADU37_CDS04480	COG0012	GTP binding
ADU37_CDS04520	COG0534	Mate efflux family protein
ADU37_CDS04530	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
ADU37_CDS04550	COG0071	Belongs to the small heat shock protein (HSP20) family
ADU37_CDS04560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU37_CDS04570	COG0693	protein deglycase activity
ADU37_CDS04630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADU37_CDS04700	COG1042	CoA-binding domain protein
ADU37_CDS04700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADU37_CDS04700	COG0045	succinate-CoA ligase (ADP-forming) activity
ADU37_CDS04710	COG1110	DNA topoisomerase II activity
ADU37_CDS04740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADU37_CDS04750	COG0482	sulfurtransferase activity
ADU37_CDS04760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADU37_CDS04810	COG0105	UTP biosynthetic process
ADU37_CDS04840	COG0312	modulator of DNA gyrase
ADU37_CDS04850	COG0312	modulator of DNA gyrase
ADU37_CDS04900	COG0598	Magnesium transport protein CorA
ADU37_CDS05000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADU37_CDS05060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADU37_CDS05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU37_CDS05160	COG0243	molybdopterin cofactor binding
ADU37_CDS05200	COG0656	L-ascorbic acid biosynthetic process
ADU37_CDS05270	COG1185	polyribonucleotide nucleotidyltransferase activity
ADU37_CDS05310	COG1085	galactose-1-phosphate uridylyltransferase
ADU37_CDS05320	COG2723	6-phospho-beta-galactosidase activity
ADU37_CDS05350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADU37_CDS05360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADU37_CDS05370	COG4221	oxidoreductase activity
ADU37_CDS05500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU37_CDS05510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADU37_CDS05570	COG0252	asparaginase activity
ADU37_CDS05580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADU37_CDS05590	COG0733	neurotransmitter:sodium symporter activity
ADU37_CDS05640	COG0058	SHG alpha-glucan phosphorylase activity
ADU37_CDS05650	COG1122	ATPase activity
ADU37_CDS05680	COG0310	cobalt ion transport
ADU37_CDS05710	COG0517	IMP dehydrogenase activity
ADU37_CDS05710	COG0516	GMP reductase activity
ADU37_CDS05730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADU37_CDS05740	COG1968	undecaprenyl-diphosphatase activity
ADU37_CDS05750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU37_CDS05760	COG1863	multisubunit Na H antiporter MnhE subunit
ADU37_CDS05770	COG2212	antiporter activity
ADU37_CDS05780	COG1320	monovalent cation:proton antiporter activity
ADU37_CDS05830	COG0651	ATP synthesis coupled electron transport
ADU37_CDS05850	COG3260	NADH ubiquinone oxidoreductase 20
ADU37_CDS05860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS05880	COG0650	Formate hydrogenlyase subunit 4
ADU37_CDS05910	COG2212	antiporter activity
ADU37_CDS05920	COG1320	monovalent cation:proton antiporter activity
ADU37_CDS05960	COG1006	Multisubunit Na H antiporter MnhC subunit
ADU37_CDS05970	COG0651	ATP synthesis coupled electron transport
ADU37_CDS05990	COG3260	NADH ubiquinone oxidoreductase 20
ADU37_CDS06000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS06020	COG0650	Formate hydrogenlyase subunit 4
ADU37_CDS06030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS06050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADU37_CDS06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADU37_CDS06080	COG0501	Belongs to the peptidase M48B family
ADU37_CDS06090	COG2131	deaminase
ADU37_CDS06120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADU37_CDS06190	COG1836	PFAM Integral membrane protein DUF92
ADU37_CDS06200	COG1522	sequence-specific DNA binding
ADU37_CDS06210	COG1694	Mazg nucleotide pyrophosphohydrolase
ADU37_CDS06260	COG1192	Involved in chromosome partitioning
ADU37_CDS06270	COG2211	Major facilitator Superfamily
ADU37_CDS06320	COG1872	DUF167
ADU37_CDS06410	COG0423	glycine-tRNA ligase activity
ADU37_CDS06440	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ADU37_CDS06460	COG0303	'Molybdopterin
ADU37_CDS06520	COG0697	spore germination
ADU37_CDS06540	COG2414	aldehyde ferredoxin oxidoreductase
ADU37_CDS06610	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADU37_CDS06650	COG1121	(ABC) transporter
ADU37_CDS06690	COG1205	dead DEAH box helicase
ADU37_CDS06690	COG1111	helicase
ADU37_CDS06720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ADU37_CDS06750	COG0330	HflC and HflK could
ADU37_CDS06760	COG2894	cell division
ADU37_CDS06810	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ADU37_CDS06860	COG0513	Belongs to the DEAD box helicase family
ADU37_CDS06870	COG1342	Belongs to the UPF0251 family
ADU37_CDS06880	COG0489	protein tyrosine kinase activity
ADU37_CDS06890	COG0489	protein tyrosine kinase activity
ADU37_CDS07090	COG0109	protoheme IX farnesyltransferase activity
ADU37_CDS07110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADU37_CDS07120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADU37_CDS07280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADU37_CDS07290	COG4608	Belongs to the ABC transporter superfamily
ADU37_CDS07300	COG0444	Belongs to the ABC transporter superfamily
ADU37_CDS07310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU37_CDS07320	COG0601	transmembrane transport
ADU37_CDS07340	COG2723	6-phospho-beta-galactosidase activity
ADU37_CDS07540	COG0235	Class ii aldolase
ADU37_CDS07560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADU37_CDS07580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADU37_CDS07590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ADU37_CDS07600	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ADU37_CDS07660	COG1793	dna ligase
ADU37_CDS07690	COG1757	Na H antiporter
ADU37_CDS07700	COG1573	uracil-dna glycosylase
ADU37_CDS07730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU37_CDS07760	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
ADU37_CDS07820	COG0037	tRNA processing
ADU37_CDS07850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADU37_CDS07870	COG0681	Belongs to the peptidase S26 family
ADU37_CDS07920	COG0482	sulfurtransferase activity
ADU37_CDS08010	COG0527	aspartate kinase activity
ADU37_CDS08030	COG0083	homoserine kinase activity
ADU37_CDS08050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADU37_CDS08250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADU37_CDS08260	COG0477	Major facilitator Superfamily
ADU37_CDS08270	COG0006	proline dipeptidase activity
ADU37_CDS08290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADU37_CDS08360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ADU37_CDS08380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADU37_CDS08390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADU37_CDS08400	COG0442	prolyl-tRNA aminoacylation
ADU37_CDS08410	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ADU37_CDS08440	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ADU37_CDS08450	COG1213	nucleotidyl transferase
ADU37_CDS08450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADU37_CDS08460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADU37_CDS08460	COG1213	nucleotidyl transferase
ADU37_CDS08470	COG2414	aldehyde ferredoxin oxidoreductase
ADU37_CDS08500	COG1115	amino acid carrier protein
ADU37_CDS08510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU37_CDS08530	COG0489	protein tyrosine kinase activity
ADU37_CDS08550	COG0017	Asparaginyl-tRNA synthetase
ADU37_CDS08570	COG0402	S-adenosylhomocysteine deaminase activity
ADU37_CDS08670	COG0569	domain protein
ADU37_CDS08730	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
ADU37_CDS08750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADU37_CDS08760	COG0501	Belongs to the peptidase M48B family
ADU37_CDS08820	COG0525	valine-tRNA ligase activity
ADU37_CDS08860	COG1056	cytidyltransferase-related domain
ADU37_CDS08860	COG1051	belongs to the nudix hydrolase family
ADU37_CDS08960	COG0560	Phosphoserine phosphatase
ADU37_CDS08970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADU37_CDS09000	COG0175	sulfate reduction
ADU37_CDS09040	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADU37_CDS09070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADU37_CDS09160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADU37_CDS09290	COG1078	dGTPase activity
ADU37_CDS09320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADU37_CDS09350	COG0517	IMP dehydrogenase activity
ADU37_CDS09350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADU37_CDS09390	COG1199	ATP-dependent helicase activity
ADU37_CDS09420	COG1489	DNA binding
ADU37_CDS09440	COG4974	Belongs to the 'phage' integrase family
ADU37_CDS09470	COG1355	regulation of microtubule-based process
ADU37_CDS09490	COG0584	glycerophosphoryl diester phosphodiesterase
ADU37_CDS09510	COG0579	oxidoreductase
ADU37_CDS09570	COG2339	peptidase activity
ADU37_CDS09610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU37_CDS09620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU37_CDS09630	COG0312	modulator of DNA gyrase
ADU37_CDS09660	COG0312	modulator of DNA gyrase
ADU37_CDS09680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADU37_CDS09680	COG0493	'glutamate synthase
ADU37_CDS09690	COG0543	2 iron, 2 sulfur cluster binding
ADU37_CDS09750	COG1304	FMN binding
ADU37_CDS09860	COG1506	peptidase
ADU37_CDS09860	COG4946	Tricorn protease homolog
ADU37_CDS09860	COG0823	Involved in the tonB-independent uptake of proteins
ADU37_CDS09880	COG0747	negative chemotaxis
ADU37_CDS09890	COG0601	transmembrane transport
ADU37_CDS09900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU37_CDS09910	COG0444	Belongs to the ABC transporter superfamily
ADU37_CDS09920	COG4608	Belongs to the ABC transporter superfamily
ADU37_CDS09950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADU37_CDS10000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADU37_CDS10010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADU37_CDS10020	COG0066	3-isopropylmalate dehydratase activity
ADU37_CDS10030	COG0473	3-isopropylmalate dehydrogenase activity
ADU37_CDS10050	COG0189	ligase activity
ADU37_CDS10060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADU37_CDS10080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADU37_CDS10090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU37_CDS10120	COG3959	Transketolase, thiamine diphosphate binding domain
ADU37_CDS10130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADU37_CDS10140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADU37_CDS10160	COG0710	3-dehydroquinate dehydratase activity
ADU37_CDS10170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADU37_CDS10210	COG1605	Chorismate mutase
ADU37_CDS10210	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADU37_CDS10220	COG0436	Aminotransferase
ADU37_CDS10250	COG0133	tryptophan synthase activity
ADU37_CDS10260	COG0135	phosphoribosylanthranilate isomerase activity
ADU37_CDS10270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADU37_CDS10270	COG0512	Glutamine amidotransferase of anthranilate synthase
ADU37_CDS10280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADU37_CDS10290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADU37_CDS10370	COG2078	PFAM AMMECR1 domain protein
ADU37_CDS10370	COG3885	ferrous iron binding
ADU37_CDS10380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADU37_CDS10400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU37_CDS10400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU37_CDS10430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADU37_CDS10530	COG2264	protein methyltransferase activity
ADU37_CDS10610	COG1132	(ABC) transporter
ADU37_CDS10620	COG1132	(ABC) transporter
ADU37_CDS10690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADU37_CDS10720	COG0148	phosphopyruvate hydratase activity
ADU37_CDS10830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADU37_CDS10910	COG2192	nodulation
ADU37_CDS10920	COG0436	Aminotransferase
ADU37_CDS10990	COG0588	phosphoglycerate mutase activity
ADU37_CDS11050	COG1765	OsmC-like protein
ADU37_CDS11070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADU37_CDS11160	COG0864	Transcriptional regulator
ADU37_CDS11180	COG0163	prenyltransferase activity
ADU37_CDS11210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ADU37_CDS11230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ADU37_CDS11240	COG1984	allophanate hydrolase subunit 2
ADU37_CDS11260	COG1454	alcohol dehydrogenase
ADU37_CDS11280	COG0483	inositol monophosphate 1-phosphatase activity
ADU37_CDS11310	COG1196	nuclear chromosome segregation
ADU37_CDS11380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADU37_CDS11420	COG0011	TIGRFAM Protein of
ADU37_CDS11470	COG1268	BioY protein
ADU37_CDS11490	COG1122	ATPase activity
ADU37_CDS11500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADU37_CDS11610	COG4946	Tricorn protease homolog
ADU37_CDS11610	COG1506	peptidase
ADU37_CDS11610	COG0823	Involved in the tonB-independent uptake of proteins
ADU37_CDS11620	COG1444	tRNA N-acetyltransferase activity
ADU37_CDS11660	COG1476	TRANSCRIPTIONal
ADU37_CDS11680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU37_CDS11690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADU37_CDS11770	COG2226	methyltransferase
ADU37_CDS11780	COG0011	TIGRFAM Protein of
ADU37_CDS11790	COG0563	adenylate kinase activity
ADU37_CDS11830	COG1863	multisubunit Na H antiporter MnhE subunit
ADU37_CDS11840	COG2212	antiporter activity
ADU37_CDS11900	COG0651	ATP synthesis coupled electron transport
ADU37_CDS11940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ADU37_CDS11950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADU37_CDS12000	COG1402	creatininase
ADU37_CDS12020	COG0589	response to stress
ADU37_CDS12030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADU37_CDS12190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADU37_CDS12230	COG2267	carboxylic ester hydrolase activity
ADU37_CDS12250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADU37_CDS12260	COG0746	molybdenum cofactor guanylyltransferase activity
ADU37_CDS12320	COG1234	tRNA 3'-trailer cleavage
ADU37_CDS12360	COG1994	Peptidase M50
ADU37_CDS12370	COG2140	Oxalate decarboxylase
ADU37_CDS12470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADU37_CDS12520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADU37_CDS12540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADU37_CDS12570	COG0142	geranyltranstransferase activity
ADU37_CDS12580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADU37_CDS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU37_CDS12600	COG0444	Belongs to the ABC transporter superfamily
ADU37_CDS12610	COG4608	Belongs to the ABC transporter superfamily
ADU37_CDS12650	COG0417	DNA replication proofreading
ADU37_CDS12660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADU37_CDS12660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU37_CDS12680	COG2078	PFAM AMMECR1 domain protein
ADU37_CDS12730	COG1469	GTP cyclohydrolase I activity
ADU37_CDS12780	COG2205	protein histidine kinase activity
ADU37_CDS12830	COG1131	(ABC) transporter
ADU37_CDS12880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADU37_CDS12930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADU37_CDS12940	COG0733	neurotransmitter:sodium symporter activity
ADU37_CDS12960	COG0347	Belongs to the P(II) protein family
ADU37_CDS12970	COG1543	Belongs to the glycosyl hydrolase 57 family
ADU37_CDS13010	COG1254	Belongs to the acylphosphatase family
ADU37_CDS13060	COG0167	dihydroorotate dehydrogenase activity
ADU37_CDS13070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADU37_CDS13110	COG0492	ferredoxin-NADP+ reductase activity
ADU37_CDS13120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADU37_CDS13150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ADU37_CDS13170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADU37_CDS13190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADU37_CDS13210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADU37_CDS13270	COG1518	maintenance of DNA repeat elements
ADU37_CDS13320	COG1203	CRISPR-associated helicase, Cas3
ADU37_CDS13350	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADU37_CDS13380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADU37_CDS13420	COG2819	hydrolase of the alpha beta superfamily
ADU37_CDS13440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADU37_CDS13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU37_CDS13600	COG0733	neurotransmitter:sodium symporter activity
ADU37_CDS13610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADU37_CDS13660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADU37_CDS13690	COG0556	nucleotide-excision repair
ADU37_CDS13700	COG0101	tRNA pseudouridine synthase activity
ADU37_CDS13710	COG0072	phenylalanine-tRNA ligase activity
ADU37_CDS13730	COG1063	alcohol dehydrogenase
ADU37_CDS13740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU37_CDS13750	COG2894	cell division
ADU37_CDS13820	COG2119	membrane
ADU37_CDS13860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADU37_CDS13870	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADU37_CDS13870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADU37_CDS13940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU37_CDS13940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADU37_CDS13970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ADU37_CDS14100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADU37_CDS14110	COG1185	polyribonucleotide nucleotidyltransferase activity
ADU37_CDS14140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ADU37_CDS14220	COG0504	CTP synthase activity
ADU37_CDS14270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADU37_CDS14310	COG0312	modulator of DNA gyrase
ADU37_CDS14320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADU37_CDS14350	COG1131	(ABC) transporter
ADU37_CDS14400	COG0489	protein tyrosine kinase activity
ADU37_CDS14410	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14420	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14440	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14450	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14550	COG0306	phosphate transporter
ADU37_CDS14570	COG1131	(ABC) transporter
ADU37_CDS14580	COG1476	TRANSCRIPTIONal
ADU37_CDS14620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU37_CDS14660	COG0303	'Molybdopterin
ADU37_CDS14670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADU37_CDS14710	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADU37_CDS14750	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADU37_CDS14760	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADU37_CDS14780	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14790	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS14800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADU37_CDS14840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU37_CDS14860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADU37_CDS14870	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ADU37_CDS14920	COG1201	RNA secondary structure unwinding
ADU37_CDS14940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU37_CDS14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADU37_CDS14980	COG0084	hydrolase, TatD family'
ADU37_CDS15010	COG1131	(ABC) transporter
ADU37_CDS15060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU37_CDS15070	COG0298	carbon dioxide binding
ADU37_CDS15080	COG0409	Hydrogenase expression formation protein
ADU37_CDS15150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADU37_CDS15180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADU37_CDS15200	COG0477	Major facilitator Superfamily
ADU37_CDS15240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADU37_CDS15300	COG0009	L-threonylcarbamoyladenylate synthase
ADU37_CDS15310	COG0297	glycogen (starch) synthase activity
ADU37_CDS15330	COG0367	asparagine synthase
ADU37_CDS15350	COG2894	cell division
ADU37_CDS15370	COG0424	maF-like protein
ADU37_CDS15390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ADU37_CDS15400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADU37_CDS15400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADU37_CDS15420	COG0346	lactoylglutathione lyase activity
ADU37_CDS15440	COG2239	Acts as a magnesium transporter
ADU37_CDS15550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADU37_CDS15610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADU37_CDS15660	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ADU37_CDS15670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADU37_CDS15680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ADU37_CDS15690	COG1573	uracil-dna glycosylase
ADU37_CDS15780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU37_CDS15800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ADU37_CDS15820	COG1492	cobalamin metabolic process
ADU37_CDS15830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADU37_CDS15840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ADU37_CDS15870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ADU37_CDS15890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADU37_CDS15900	COG0051	transcription antitermination factor activity, RNA binding
ADU37_CDS15940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADU37_CDS16010	COG1131	(ABC) transporter
ADU37_CDS16050	COG0315	cyclic pyranopterin monophosphate synthase activity
ADU37_CDS16060	COG1193	negative regulation of DNA recombination
ADU37_CDS16070	COG0515	serine threonine protein kinase
ADU37_CDS16110	COG1739	Uncharacterized protein family UPF0029
ADU37_CDS16130	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ADU37_CDS16140	COG0511	ligase activity, forming carbon-carbon bonds
ADU37_CDS16140	COG5016	pyruvate
ADU37_CDS16160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADU37_CDS16220	COG0430	RNA-3'-phosphate cyclase activity
ADU37_CDS16280	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADU37_CDS16320	COG0543	2 iron, 2 sulfur cluster binding
ADU37_CDS16330	COG0493	'glutamate synthase
ADU37_CDS16330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADU37_CDS16340	COG0778	Nitroreductase
ADU37_CDS16350	COG0017	Asparaginyl-tRNA synthetase
ADU37_CDS16360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADU37_CDS16370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADU37_CDS16450	COG1122	ATPase activity
ADU37_CDS16460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADU37_CDS16470	COG0024	Methionine aminopeptidase
ADU37_CDS16490	COG0309	Hydrogenase expression formation protein (HypE)
ADU37_CDS16500	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADU37_CDS16560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADU37_CDS16570	COG1435	thymidine kinase activity
ADU37_CDS16590	COG2379	hydroxypyruvate reductase
ADU37_CDS16650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADU37_CDS16660	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ADU37_CDS16760	COG0432	Pfam Uncharacterised protein family UPF0047
ADU37_CDS16810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADU37_CDS16880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADU37_CDS16910	COG0519	Catalyzes the synthesis of GMP from XMP
ADU37_CDS16910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU37_CDS16950	COG0252	asparaginase activity
ADU37_CDS16970	COG1695	Transcriptional regulator
ADU37_CDS16990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADU37_CDS16990	COG2050	protein possibly involved in aromatic compounds catabolism
ADU37_CDS17020	COG1335	isochorismatase
ADU37_CDS17030	COG0628	permease
ADU37_CDS17100	COG0463	Glycosyl transferase, family 2
ADU37_CDS17150	COG1980	fructose-bisphosphate aldolase activity
ADU37_CDS17190	COG0719	Fe-S assembly protein
ADU37_CDS17210	COG1230	cation diffusion facilitator family transporter
ADU37_CDS17250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADU37_CDS17260	COG0798	PFAM Bile acid sodium symporter
ADU37_CDS17330	COG2226	methyltransferase
ADU37_CDS17350	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ADU37_CDS17400	COG4555	ABC transporter
ADU37_CDS17460	COG4555	ABC transporter
ADU37_CDS17580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADU37_CDS17620	COG1122	ATPase activity
ADU37_CDS17710	COG0672	)-iron permease
ADU37_CDS17790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ADU37_CDS17840	COG0450	alkyl hydroperoxide reductase
ADU37_CDS17870	COG1404	Belongs to the peptidase S8 family
ADU37_CDS17880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADU37_CDS17890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADU37_CDS17910	COG0719	Fe-S assembly protein
ADU37_CDS17930	COG0396	ATPase activity
ADU37_CDS17980	COG1528	Iron-storage protein
ADU37_CDS18020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADU37_CDS18030	COG2084	Dehydrogenase
ADU37_CDS18040	COG0778	Nitroreductase
ADU37_CDS18060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADU37_CDS18080	COG1203	CRISPR-associated helicase, Cas3
ADU37_CDS18200	COG1337	RAMP superfamily
ADU37_CDS18220	COG1353	crispr-associated protein
ADU37_CDS18450	COG0426	domain, Protein
ADU37_CDS18540	COG1151	hydroxylamine reductase activity
ADU37_CDS18590	COG0459	protein refolding
ADU37_CDS18650	COG0601	transmembrane transport
ADU37_CDS18660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADU37_CDS18670	COG0444	Belongs to the ABC transporter superfamily
ADU37_CDS18680	COG4608	Belongs to the ABC transporter superfamily
ADU37_CDS18700	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADU37_CDS18720	COG0174	glutamine synthetase
ADU37_CDS18770	COG0697	spore germination
ADU37_CDS18800	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ADU37_CDS18850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADU37_CDS18880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADU37_CDS18890	COG1297	OPT oligopeptide transporter protein
ADU37_CDS18900	COG1234	tRNA 3'-trailer cleavage
ADU37_CDS18910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADU37_CDS18930	COG3842	ATPase activity
ADU37_CDS18950	COG3833	ABC-type maltose transport systems, permease component
ADU37_CDS18970	COG2182	Extracellular solute-binding protein
ADU37_CDS18990	COG1378	Sugar-specific transcriptional regulator TrmB
ADU37_CDS19000	COG0297	glycogen (starch) synthase activity
ADU37_CDS19020	COG0442	prolyl-tRNA aminoacylation
ADU37_CDS19050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS19120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADU37_CDS19130	COG1394	ATPase activity, coupled to movement of substances
ADU37_CDS19150	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ADU37_CDS19180	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
ADU37_CDS19200	COG1269	ATP hydrolysis coupled proton transport
ADU37_CDS19220	COG0569	domain protein
ADU37_CDS19230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADU37_CDS19270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ADU37_CDS19380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADU37_CDS19480	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ADU37_CDS19490	COG0463	Glycosyl transferase, family 2
ADU37_CDS19570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADU37_CDS19620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADU37_CDS19630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADU37_CDS19650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADU37_CDS19650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADU37_CDS19700	COG1510	regulation of RNA biosynthetic process
ADU37_CDS19730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADU37_CDS19740	COG0314	molybdopterin synthase activity
ADU37_CDS19760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADU37_CDS19820	COG4139	cobalamin transport
ADU37_CDS19830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ADU37_CDS19850	COG0557	exoribonuclease II activity
ADU37_CDS19860	COG1012	belongs to the aldehyde dehydrogenase family
ADU37_CDS19930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADU37_CDS20010	COG0668	transmembrane transport
ADU37_CDS20040	COG1215	transferase activity, transferring glycosyl groups
ADU37_CDS20110	COG1028	Short-chain dehydrogenase reductase Sdr
ADU37_CDS20140	COG1174	glycine betaine transport
ADU37_CDS20150	COG1125	glycine betaine transport
ADU37_CDS20150	COG0517	IMP dehydrogenase activity
ADU37_CDS20160	COG1732	Glycine betaine
ADU37_CDS20180	COG1850	ribulose-bisphosphate carboxylase activity
ADU37_CDS20220	COG2033	superoxide reductase activity
ADU37_CDS20230	COG1773	rubredoxin
ADU37_CDS20240	COG1592	Rubrerythrin
ADU37_CDS20290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADU37_CDS20300	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADU37_CDS20320	COG0450	alkyl hydroperoxide reductase
ADU37_CDS20350	COG0649	NAD binding
ADU37_CDS20360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS20370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADU37_CDS20380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADU37_CDS20400	COG0651	ATP synthesis coupled electron transport
ADU37_CDS20420	COG2111	Na H antiporter
ADU37_CDS20420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADU37_CDS20440	COG1320	monovalent cation:proton antiporter activity
ADU37_CDS20450	COG2212	antiporter activity
ADU37_CDS20460	COG1863	multisubunit Na H antiporter MnhE subunit
ADU37_CDS20480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU37_CDS20510	COG1401	restriction endodeoxyribonuclease activity
ADU37_CDS20570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU37_CDS20640	COG0018	arginyl-trna synthetase
ADU37_CDS20650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADU37_CDS20810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADU37_CDS20840	COG0714	Associated with various cellular activities
ADU37_CDS20880	COG1047	Peptidyl-prolyl cis-trans
ADU37_CDS20960	COG0116	Belongs to the methyltransferase superfamily
ADU37_CDS20960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADU37_CDS20970	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADU37_CDS21070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADU37_CDS21070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADU37_CDS21100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADU37_CDS21100	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADU37_CDS21110	COG0402	S-adenosylhomocysteine deaminase activity
ADU37_CDS21120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADU37_CDS21230	COG2274	protein secretion by the type I secretion system
ADU37_CDS21240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADU37_CDS21290	COG1122	ATPase activity
ADU37_CDS21340	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ADU37_CDS21360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADU37_CDS21410	COG1028	Short-chain dehydrogenase reductase Sdr
ADU37_CDS21420	COG1881	PFAM PEBP family protein
ADU37_CDS21480	COG0475	glutathione-regulated potassium exporter activity
ADU37_CDS21490	COG1522	sequence-specific DNA binding
ADU37_CDS21530	COG0647	UMP catabolic process
ADU37_CDS21580	COG0463	Glycosyl transferase, family 2
ADU37_CDS21610	COG1442	glycosyl transferase family 8
ADU37_CDS21610	COG1216	Glycosyl transferase, family 2
ADU37_CDS21690	COG2002	toxin-antitoxin pair type II binding
ADU37_CDS21740	COG0438	transferase activity, transferring glycosyl groups
ADU37_CDS21830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADU37_CDS21890	COG1216	Glycosyl transferase, family 2
ADU37_CDS21890	COG1442	glycosyl transferase family 8
ADU37_CDS21910	COG0438	transferase activity, transferring glycosyl groups
ADU37_CDS21940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ADU37_CDS21980	COG0539	negative regulation of cytoplasmic translation
ADU37_CDS22030	COG2890	protein-(glutamine-N5) methyltransferase activity
ADU37_CDS22180	COG0519	Catalyzes the synthesis of GMP from XMP
ADU37_CDS22180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU37_CDS22200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADU37_CDS22200	COG0519	Catalyzes the synthesis of GMP from XMP
ADU37_CDS22210	COG0517	IMP dehydrogenase activity
ADU37_CDS22210	COG0516	GMP reductase activity
ADU37_CDS22250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADU37_CDS22260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ADU37_CDS22280	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ADU37_CDS22300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADU37_CDS22330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADU37_CDS22340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADU37_CDS22340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADU37_CDS22350	COG0307	riboflavin synthase, alpha
ADU37_CDS22360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU37_CDS22360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADU37_CDS22380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ADU37_CDS22390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADU37_CDS22400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADU37_CDS22520	COG2271	Major facilitator Superfamily
ADU37_CDS22600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ADU37_CDS22600	COG5297	Belongs to the glycosyl hydrolase family 6
ADU37_CDS22660	COG0047	phosphoribosylformylglycinamidine synthase activity
ADU37_CDS22680	COG1132	(ABC) transporter
ADU37_CDS22700	COG0151	Belongs to the GarS family
ADU37_CDS22730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADU37_CDS22740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADU37_CDS22790	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADU37_CDS22800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADU37_CDS22810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADU37_CDS22820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADU37_CDS22830	COG3383	formate dehydrogenase (NAD+) activity
ADU37_CDS22870	COG0668	transmembrane transport
ADU37_CDS22920	COG1695	Transcriptional regulator