locus-tag	class	description
GQS_00050	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GQS_00070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GQS_00090	ENOG4108ZF3	Phosphatase
GQS_00095	ENOG4105D9P	serine threonine protein kinase
GQS_00105	ENOG4105D9P	serine threonine protein kinase
GQS_00110	ENOG4108ZF3	Phosphatase
GQS_00115	ENOG4105D9P	serine threonine protein kinase
GQS_00125	ENOG4105D9P	serine threonine protein kinase
GQS_00130	ENOG4105D9P	serine threonine protein kinase
GQS_00165	ENOG4105D9P	serine threonine protein kinase
GQS_00175	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GQS_00215	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GQS_00225	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GQS_00230	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GQS_00235	ENOG4105C5I	Dehydrogenase
GQS_00265	ENOG4107WZZ	SMC domain protein
GQS_00265	ENOG4107WZZ	SMC domain protein
GQS_00295	ENOG4105F8V	Hydrolase, tatD family
GQS_00310	ENOG4107VMB	Beta-lactamase domain protein
GQS_00315	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GQS_00320	ENOG4107QRT	dEAD DEAH box helicase
GQS_00330	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GQS_00345	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GQS_00370	ENOG4105C83	adenylosuccinate lyase
GQS_00380	ENOG4105VYW	UPF0251 protein
GQS_00445	ENOG4108R96	Methyltransferase, YaeB family
GQS_00485	ENOG4107QMS	site-determining protein
GQS_00505	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GQS_00520	ENOG4105E5G	Alpha beta hydrolase fold
GQS_00525	ENOG4107QSA	Oxaloacetate decarboxylase
GQS_00530	ENOG41061GT	Aldolase
GQS_00550	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GQS_00570	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GQS_00575	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GQS_00605	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GQS_00635	ENOG4105CIG	ABC transporter
GQS_00690	ENOG4108YZ8	Superoxide reductase
GQS_00695	ENOG4105VCQ	rubredoxin
GQS_00700	ENOG4108RAC	Rubrerythrin
GQS_00715	ENOG4105F4P	)-transporter
GQS_00730	ENOG4108HJF	gCN5-related N-acetyltransferase
GQS_00760	ENOG4105DXX	methyltransferase
GQS_00780	ENOG4105D3R	alkyl hydroperoxide reductase
GQS_00785	ENOG4108J2R	molybdopterin oxidoreductase
GQS_00840	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GQS_00875	ENOG4105CIG	ABC transporter
GQS_00895	ENOG41079KZ	Major Facilitator Superfamily
GQS_00935	ENOG4105D64	Mechanosensitive ion channel
GQS_00940	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GQS_00945	ENOG4105KJJ	Uncharacterized ACR, COG1993
GQS_00950	ENOG4105WMR	Protein CrcB homolog
GQS_00970	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS_00980	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GQS_01000	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GQS_01015	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GQS_01025	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GQS_01035	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GQS_01045	ENOG4105FDK	ABC transporter
GQS_01085	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GQS_01100	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
GQS_01115	ENOG4105DCI	Phosphohydrolase
GQS_01120	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GQS_01130	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GQS_01135	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GQS_01145	ENOG4105DZR	Type I site-specific deoxyribonuclease
GQS_01165	ENOG4107XZC	Restriction modification system DNA (Specificity
GQS_01180	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
GQS_01185	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GQS_01250	ENOG4105FDK	ABC transporter
GQS_01255	ENOG4108I5C	dEAD DEAH box helicase
GQS_01260	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GQS_01290	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GQS_01295	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GQS_01305	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GQS_01335	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GQS_01345	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GQS_01360	ENOG4105D0M	Protease HtpX homolog
GQS_01370	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GQS_01375	ENOG4105E0R	Deoxyhypusine synthase
GQS_01390	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GQS_01405	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GQS_01430	ENOG4108SA1	esterase
GQS_01445	ENOG4105DCI	Phosphohydrolase
GQS_01470	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GQS_01485	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
GQS_01505	ENOG4108K7V	UPF0284 protein
GQS_01515	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GQS_01520	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GQS_01530	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GQS_01535	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GQS_01540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GQS_01555	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GQS_01570	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GQS_01575	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GQS_01595	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GQS_01620	ENOG4105CG9	aspartate racemase
GQS_01625	ENOG4105D7N	magnesium and cobalt transport protein CorA
GQS_01630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GQS_01640	ENOG4105C3G	gtp-binding protein
GQS_01650	ENOG4108VVK	transcriptional Regulator, AsnC
GQS_01655	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GQS_01690	ENOG4105CE1	Ferrous iron transport protein b
GQS_01705	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GQS_01730	ENOG4105DC7	peptidase M24
GQS_01745	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
GQS_01755	ENOG4105UQX	Mate efflux family protein
GQS_01770	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GQS_01780	ENOG4105VZ9	UPF0235 protein
GQS_01795	ENOG4105CEV	competence damage-inducible protein
GQS_01810	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GQS_01820	ENOG4108WBT	adenosyltransferase
GQS_01860	ENOG4105EYF	MMPL domain protein
GQS_01870	ENOG4105DER	m42 family
GQS_01955	ENOG4107QJZ	Glycosyl transferase, family 2
GQS_01990	ENOG4108IA2	Sodium pantothenate symporter
GQS_02005	ENOG4105C8V	SAICAR synthetase
GQS_02015	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
GQS_02020	ENOG4107ZCS	Phosphomethylpyrimidine kinase
GQS_02050	ENOG4105C8N	cysteinyl-tRNA synthetase
GQS_02055	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GQS_02080	ENOG4105UIB	(ABC) transporter
GQS_02085	ENOG4108JQ9	ABC transporter
GQS_02090	ENOG4105DIH	basic membrane
GQS_02100	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GQS_02110	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GQS_02125	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GQS_02130	ENOG4105DQU	oxidoreductase, subunit beta
GQS_02140	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GQS_02145	ENOG4105DQU	oxidoreductase, subunit beta
GQS_02170	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GQS_02230	ENOG4105C5I	Dehydrogenase
GQS_02235	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GQS_02260	ENOG4105CHM	Aminotransferase
GQS_02270	ENOG4105D0M	Protease HtpX homolog
GQS_02275	ENOG4107RB4	Cytidine monophosphate kinase
GQS_02285	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
GQS_02295	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GQS_02335	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GQS_02350	ENOG4105E3S	small subunit
GQS_02365	ENOG4108393	oxidoreductase Fe-S subunit
GQS_02380	ENOG4105D65	subunit l
GQS_02390	ENOG4108ZE9	Monovalent cation H antiporter subunit C
GQS_02420	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GQS_02425	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
GQS_02430	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_02435	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GQS_02440	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_02445	ENOG4105D65	subunit l
GQS_02450	ENOG4105QAX	Iron-sulfur
GQS_02455	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GQS_02475	ENOG4105DPX	Hydrogenase, large subunit
GQS_02495	ENOG4105DIW	FeS assembly protein SUFB
GQS_02500	ENOG4105C3K	feS assembly ATPase SufC
GQS_02505	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GQS_02515	ENOG4105KME	endoribonuclease L-psp
GQS_02530	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GQS_02535	ENOG4108VVK	transcriptional Regulator, AsnC
GQS_02545	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GQS_02565	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GQS_02640	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GQS_02650	ENOG4105C75	arginyL-tRNA synthetase
GQS_02680	ENOG4108IJ1	Dehydrogenase
GQS_02685	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GQS_02700	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GQS_02710	ENOG4105SC1	monovalent cation H antiporter subunit E
GQS_02715	ENOG410684G	monovalent cation H antiporter subunit F
GQS_02720	ENOG4105KJM	monovalent cation h antiporter subunit g
GQS_02730	ENOG4105D65	subunit l
GQS_02735	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GQS_02740	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_02745	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_02755	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_02760	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_02765	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_02790	ENOG4108JPW	Aminotransferase
GQS_02795	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
GQS_02815	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GQS_02850	ENOG4108V1U	phospholipid-binding protein
GQS_02880	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GQS_02885	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GQS_02890	ENOG4105KTU	Transcriptional regulator, arsr family
GQS_02955	ENOG4105BZR	domain protein
GQS_02975	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GQS_03000	ENOG4105E3H	phosphoglycerate mutase
GQS_03015	ENOG4107S6Z	Na H antiporter
GQS_03025	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GQS_03035	ENOG4105DBV	ornithine carbamoyltransferase
GQS_03040	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GQS_03100	ENOG4105CMQ	Chloride channel
GQS_03110	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GQS_03115	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GQS_03125	ENOG4105CG5	Glycosyl transferase (Group 1
GQS_03195	ENOG4105HDK	L-asparaginase
GQS_03230	ENOG4107QMS	site-determining protein
GQS_03235	ENOG4105CPQ	Dehydrogenase
GQS_03240	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GQS_03255	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GQS_03260	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GQS_03265	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GQS_03270	ENOG4105DA5	(ABC) transporter
GQS_03295	ENOG4105EEI	dihydropteroate synthase
GQS_03300	ENOG4105F4G	Membrane
GQS_03350	ENOG4105C22	threonyL-tRNA synthetase
GQS_03365	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GQS_03370	ENOG4108Z0R	Transferase
GQS_03385	ENOG4105CN9	Peptidase m42 family protein
GQS_03410	ENOG4108JJB	ABC transporter
GQS_03415	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GQS_03420	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GQS_03425	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GQS_03435	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GQS_03450	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_03470	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GQS_03490	ENOG4105CH2	amidohydrolase
GQS_03505	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GQS_03520	ENOG4105C5S	asparaginyl-tRNA synthetase
GQS_03545	ENOG4107XGZ	Hydrolase
GQS_03555	ENOG4108VA3	3-hexulose-6-phosphate synthase
GQS_03595	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
GQS_03615	ENOG4105CD5	CoA-binding domain protein
GQS_03655	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GQS_03665	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GQS_03675	ENOG4108JU3	Alkyl hydroperoxide reductase
GQS_03690	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GQS_03695	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GQS_03700	ENOG4108T9Q	UPF0278 protein
GQS_03730	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GQS_03745	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GQS_03750	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GQS_03765	ENOG4105DHP	deoxycytidine triphosphate deaminase
GQS_03795	ENOG4105CX6	glutaminyL-tRNA synthetase
GQS_03805	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GQS_03810	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
GQS_03825	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GQS_03860	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GQS_03865	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GQS_03870	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GQS_03935	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_03940	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_03950	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GQS_03960	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GQS_03980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GQS_03995	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GQS_04015	ENOG4105CHM	Aminotransferase
GQS_04040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GQS_04075	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GQS_04085	ENOG4108Y83	glucose-6-phosphate isomerase
GQS_04115	ENOG4107G87	m6 family metalloprotease domain protein
GQS_04140	ENOG4105D6J	arsenicaL-resistance protein
GQS_04180	ENOG4105DIW	FeS assembly protein SUFB
GQS_04185	ENOG4108IUZ	ABC transporter
GQS_04190	ENOG4107SJI	Dehydrogenase
GQS_04210	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
GQS_04240	ENOG4105CQS	hydrogenase expression formation protein HypD
GQS_04260	ENOG4105C45	hydrogenase expression formation protein (HypE)
GQS_04280	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GQS_04290	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_04305	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GQS_04320	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GQS_04350	ENOG4105UQX	Mate efflux family protein
GQS_04360	ENOG4105UQX	Mate efflux family protein
GQS_04365	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GQS_04370	ENOG4105E66	phosphoriboisomerase A
GQS_04385	ENOG4105CY0	Metallo-Beta-Lactamase
GQS_04390	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GQS_04405	ENOG4105D82	Glutamate dehydrogenase
GQS_04410	ENOG4105C8J	)-transporter
GQS_04425	ENOG4108YZA	Nitrogen regulatory protein pii
GQS_04430	ENOG4107RFW	hydrolase family 57
GQS_04445	ENOG4105MRR	Transcriptional regulator (By similarity)
GQS_04500	ENOG4105DC7	peptidase M24
GQS_04510	ENOG4105C8T	Leucyl-tRNA synthetase
GQS_04520	ENOG4105C57	major facilitator superfamily
GQS_04525	ENOG4105EAH	synthase
GQS_04535	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GQS_04540	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
GQS_04545	ENOG4108XIB	electron transport protein ysaA
GQS_04550	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_04570	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GQS_04580	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
GQS_04585	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GQS_04590	ENOG4108I5U	Uridine phosphorylase
GQS_04600	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GQS_04615	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GQS_04625	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQS_04640	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GQS_04650	ENOG4108YXU	transcriptional regulator AsnC family
GQS_04670	ENOG4105CE9	30S ribosomal protein S2
GQS_04690	ENOG4108UJD	30S ribosomal protein S9
GQS_04695	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GQS_04710	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GQS_04715	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GQS_04720	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS_04725	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GQS_04735	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GQS_04745	ENOG4108Z4J	Cytidine monophosphate kinase
GQS_04765	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GQS_04770	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GQS_04775	ENOG410849U	50S ribosomal protein L30
GQS_04780	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GQS_04785	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GQS_04800	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GQS_04805	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GQS_04815	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS_04825	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GQS_04830	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GQS_04835	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GQS_04845	ENOG4108ZJT	translation initiation factor, Sui1
GQS_04850	ENOG41082SA	50s ribosomal protein l29
GQS_04855	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GQS_04865	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GQS_04870	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS_04875	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GQS_04885	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GQS_04920	ENOG4105C5R	Aminotransferase
GQS_04935	ENOG4105C5S	asparaginyl-tRNA synthetase
GQS_04965	ENOG4107QIZ	NADH dehydrogenase
GQS_04980	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GQS_05015	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
GQS_05050	ENOG4105D8K	carboxyl transferase
GQS_05060	ENOG4107QSA	Oxaloacetate decarboxylase
GQS_05065	ENOG4105D9Q	decarboxylase (Beta subunit)
GQS_05070	ENOG4105C2X	Arabinose 5-phosphate isomerase
GQS_05105	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GQS_05110	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GQS_05115	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GQS_05190	ENOG4108RWI	nicotinamidase
GQS_05200	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GQS_05210	ENOG4105VUN	Transcriptional regulator
GQS_05230	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GQS_05270	ENOG4105CQ2	DNA polymerase
GQS_05280	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GQS_05285	ENOG4105NBF	ammecr1 domain protein
GQS_05315	ENOG4106SMU	thiamine transporter membrane protein
GQS_05320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GQS_05340	ENOG4105C7N	Xanthine uracil vitamin C permease
GQS_05375	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GQS_05385	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GQS_05390	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GQS_05415	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GQS_05450	ENOG4105D64	Mechanosensitive ion channel
GQS_05455	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GQS_05465	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GQS_05485	ENOG4105K8R	UPF0145 protein
GQS_05550	ENOG4105IIU	Aminopeptidase
GQS_05620	ENOG4105F0N	pyrophosphate phospho-hydrolase
GQS_05650	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GQS_05720	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GQS_05735	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GQS_05745	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GQS_05755	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GQS_05770	ENOG4107QNG	Phosphoribosylglycinamide synthetase
GQS_05775	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GQS_05780	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GQS_05785	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GQS_05795	ENOG4105C8V	SAICAR synthetase
GQS_05815	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GQS_05820	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GQS_05825	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GQS_05830	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GQS_05835	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GQS_05840	ENOG4108IYU	L-aspartate oxidase
GQS_05850	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GQS_05880	ENOG4105EET	magnesium chelatase
GQS_05885	ENOG4105CTK	cobaltochelatase, cobn subunit
GQS_05890	ENOG4108HWH	(ABC) transporter
GQS_05895	ENOG4105EHG	Permease protein
GQS_05910	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GQS_05960	ENOG4107RA4	Glycosyl transferase (Group 1
GQS_05995	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
GQS_06000	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GQS_06030	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GQS_06075	ENOG4105CPK	Glycosyl transferase (Group 1
GQS_06085	ENOG4108I69	Glycosyl transferases group 1
GQS_06105	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GQS_06110	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GQS_06120	ENOG4105M7V	2'-5' rna ligase
GQS_06155	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GQS_06195	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GQS_06200	ENOG4108NGU	Transcriptional regulator
GQS_06210	ENOG4107FKK	extracellular solute-binding protein family 1
GQS_06220	ENOG4105EG2	ABC transporter, permease
GQS_06240	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GQS_06250	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GQS_06255	ENOG4105EPD	Oligopeptide transporter, Opt family
GQS_06265	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GQS_06275	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GQS_06285	ENOG4105CPP	Dehydrogenase, E1 component
GQS_06290	ENOG4107RUY	(E1 component), alpha subunit
GQS_06305	ENOG4105CPP	Dehydrogenase, E1 component
GQS_06310	ENOG4107RUY	(E1 component), alpha subunit
GQS_06315	ENOG4107QKR	Dehydrogenase
GQS_06320	ENOG4105C7S	Dehydrogenase
GQS_06325	ENOG4106Z86	ATP-nad acox kinase
GQS_06330	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
GQS_06335	ENOG4105DR4	Methyltransferase
GQS_06355	ENOG4105EHU	Circadian clock protein KaiC
GQS_06385	ENOG4105C5F	glutamine synthetase
GQS_06395	ENOG4105C4K	Nad synthetase
GQS_06405	ENOG4108JQ7	(ABC) transporter
GQS_06410	ENOG4105C3U	ABC transporter
GQS_06415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GQS_06440	ENOG4105CD3	dihydroorotase
GQS_06470	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GQS_06475	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GQS_06480	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GQS_06485	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
GQS_06490	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
GQS_06505	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GQS_06525	ENOG4105C1A	potassium transporter peripheral membrane
GQS_06530	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GQS_06535	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GQS_06540	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
GQS_06550	ENOG4105EHU	Circadian clock protein KaiC
GQS_06595	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
GQS_06615	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GQS_06685	ENOG4105CUT	histidyl-tRNA synthetase
GQS_06695	ENOG4107RWR	Sodium hydrogen exchanger
GQS_06700	ENOG4107RWR	Sodium hydrogen exchanger
GQS_06705	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GQS_06710	ENOG4105DZ0	fad dependent oxidoreductase
GQS_06720	ENOG4107R56	PP-loop domain protein
GQS_06735	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
GQS_06760	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GQS_06765	ENOG4105CVK	Glutamate decarboxylase
GQS_06780	ENOG4107RIQ	Sulfate adenylate transferase
GQS_06795	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
GQS_06800	ENOG4107TSN	permease
GQS_06810	ENOG4105CBG	Sulfatase
GQS_06835	ENOG4105CBG	Sulfatase
GQS_06845	ENOG4105C0H	protease
GQS_06850	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GQS_06885	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GQS_06890	ENOG4107SCK	Monooxygenase
GQS_06900	ENOG4105CTD	carboxy-peptidase
GQS_06920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GQS_06945	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GQS_06980	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GQS_06995	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GQS_07015	ENOG4105ERH	Fumarylacetoacetate hydrolase
GQS_07070	ENOG4105CD5	CoA-binding domain protein
GQS_07075	ENOG41082SX	arsR family transcriptional regulator
GQS_07090	ENOG4105E5K	Alpha-amylase
GQS_07100	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GQS_07110	ENOG4105D1H	recombination factor protein RarA
GQS_07120	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GQS_07130	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GQS_07180	ENOG4105EYW	Ion transport protein
GQS_07245	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GQS_07255	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GQS_07270	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GQS_07310	ENOG4105D06	uba thif-type nad fad binding protein
GQS_07320	ENOG4108ZAF	Molybdopterin
GQS_07340	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GQS_07345	ENOG4108VVK	transcriptional Regulator, AsnC
GQS_07370	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GQS_07385	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GQS_07400	ENOG4108JPW	Aminotransferase
GQS_07405	ENOG4105C3M	thioredoxin reductase
GQS_07420	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GQS_07445	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_07450	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GQS_07460	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
GQS_07465	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQS_07470	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GQS_07480	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_07485	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GQS_07490	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
GQS_07505	ENOG4105KJM	monovalent cation h antiporter subunit g
GQS_07510	ENOG41080TA	Multiple resistance and ph regulation protein f
GQS_07520	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GQS_07525	ENOG4107TDF	Formate hydrogenlyase subunit 4
GQS_07530	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
GQS_07535	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQS_07540	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GQS_07550	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_07575	ENOG4105KJM	monovalent cation h antiporter subunit g
GQS_07580	ENOG41080TA	Multiple resistance and ph regulation protein f
GQS_07585	ENOG4105SC1	monovalent cation H antiporter subunit E
GQS_07595	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GQS_07605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GQS_07635	ENOG4105CJ3	phosphate transporter
GQS_07685	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GQS_07725	ENOG4108IGT	Dipeptidase
GQS_07740	ENOG4105VFR	signal peptidase
GQS_07745	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
GQS_07785	ENOG4105C0D	helicase
GQS_07795	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GQS_07805	ENOG4107W7X	Aldolase
GQS_07830	ENOG41067MG	lrgb family
GQS_07835	ENOG4105VAW	lrga family
GQS_07850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GQS_07860	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GQS_07870	ENOG4107S6Z	Na H antiporter
GQS_07890	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
GQS_07900	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GQS_07905	ENOG4107QMS	site-determining protein
GQS_07915	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GQS_07920	ENOG4108VVK	transcriptional Regulator, AsnC
GQS_07930	ENOG4107NFR	Fructose-1,6-bisphosphatase
GQS_08025	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GQS_08045	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GQS_08055	ENOG4108RVA	ribokinase
GQS_08085	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GQS_08090	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GQS_08105	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GQS_08110	ENOG4105DDK	oxidoreductase, beta subunit
GQS_08115	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GQS_08125	ENOG4105DDK	oxidoreductase, beta subunit
GQS_08130	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GQS_08145	ENOG4105CJ3	phosphate transporter
GQS_08150	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GQS_08180	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GQS_08195	ENOG4107GFK	fumarate
GQS_08210	ENOG4105CWC	Acetylornithine deacetylase
GQS_08250	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GQS_08290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GQS_08340	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GQS_08345	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GQS_08365	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GQS_08380	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GQS_08385	ENOG4105CXT	aspartate transcarbamylase
GQS_08395	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GQS_08415	ENOG4108FN7	Aldo keto reductase
GQS_08420	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GQS_08430	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GQS_08435	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GQS_08455	ENOG4105C7B	Threonine dehydratase
GQS_08465	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GQS_08470	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GQS_08475	ENOG4105EHG	Permease protein
GQS_08500	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GQS_08505	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GQS_08535	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GQS_08560	ENOG4105EHU	Circadian clock protein KaiC
GQS_08575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GQS_08600	ENOG4105DK7	lysyl-tRNA synthetase
GQS_08620	ENOG4105D44	asparaginase
GQS_08630	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GQS_08655	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GQS_08665	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GQS_08670	ENOG4105CKK	Glycosyl transferase, family 2
GQS_08680	ENOG4108UK2	deaminase
GQS_08685	ENOG4105D0M	Protease HtpX homolog
GQS_08710	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
GQS_08715	ENOG4105BZ8	glutamate synthase
GQS_08735	ENOG4105CHR	reductase
GQS_08745	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
GQS_08750	ENOG4105VG1	fes assembly suf system protein
GQS_08760	ENOG4108JVH	Protein of unknown function DUF43
GQS_08770	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GQS_08780	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GQS_08785	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GQS_08805	ENOG41080HI	glycine oxidase
GQS_08810	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GQS_08845	ENOG4105CS2	ec 3.2.1.21
GQS_08850	ENOG4105D2S	major facilitator superfamily
GQS_08860	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GQS_08875	ENOG4105CK7	Sodium proline symporter
GQS_08910	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_08920	ENOG4107R7Y	intracellular protease Pfpi family
GQS_08960	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GQS_08965	ENOG4108UKZ	OsmC family
GQS_08980	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GQS_08985	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
GQS_09005	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GQS_09080	ENOG4105CK7	Sodium proline symporter
GQS_09085	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
GQS_09135	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GQS_09155	ENOG4108ZP8	Acetolactate synthase small subunit
GQS_09160	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GQS_09185	ENOG4105KJM	monovalent cation h antiporter subunit g
GQS_09190	ENOG41080TA	Multiple resistance and ph regulation protein f
GQS_09195	ENOG4105SC1	monovalent cation H antiporter subunit E
GQS_09200	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GQS_09215	ENOG4105BZ8	glutamate synthase
GQS_09220	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
GQS_09250	ENOG4105DEF	Extracellular solute-binding protein, family 5
GQS_09255	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GQS_09260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GQS_09270	ENOG4108JQ7	(ABC) transporter
GQS_09305	ENOG4105CJ1	ABC, transporter
GQS_09315	ENOG4105VZ8	Transcriptional regulator
GQS_09360	ENOG4105CHM	Aminotransferase
GQS_09375	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GQS_09380	ENOG4107QJE	Chromosome Partitioning Protein
GQS_09390	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GQS_09400	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GQS_09430	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GQS_09445	ENOG4105CJ1	ABC, transporter
GQS_09490	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GQS_09495	ENOG4107104	thymidine kinase
GQS_09535	ENOG4105D7K	pfkb domain protein
GQS_09540	ENOG4106J7S	Glycosyl transferase, family 2
GQS_09550	ENOG4105CK5	oxidoreductase
GQS_09570	ENOG4108IJ9	(ABC) transporter
GQS_09580	ENOG4105D1Z	hydroxypyruvate reductase
GQS_09610	ENOG4105K4P	CoA-binding domain protein
GQS_09635	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GQS_09655	ENOG41066FR	extracellular solute-binding protein
GQS_09660	ENOG4108I5D	sulfate abc transporter
GQS_09665	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GQS_09675	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GQS_09680	ENOG4106IPI	cyclase, family
GQS_09695	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GQS_09700	ENOG4105EAC	phosphoserine phosphatase
GQS_09780	ENOG4108R6G	acetyltransferase
GQS_09805	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
GQS_09830	ENOG4105D9U	N-acetyltransferase
GQS_09865	ENOG4108TVJ	Nitroreductase
GQS_09870	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
GQS_09880	ENOG4108JQ7	(ABC) transporter
GQS_09890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GQS_09895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GQS_09900	ENOG4105DEF	Extracellular solute-binding protein, family 5
GQS_09950	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GQS_09955	ENOG4107Y70	Heat shock protein
GQS_09965	ENOG4107T0X	DNA ligase
GQS_10055	ENOG4105CD5	CoA-binding domain protein
GQS_10075	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GQS_10095	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GQS_10100	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GQS_10120	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GQS_10135	ENOG4105CAQ	asparagine synthetase
GQS_10150	ENOG4105CTP	PilT protein domain protein
GQS_10165	ENOG4108Z03	MAF-like protein
GQS_10175	ENOG4105DCG	PHP domain protein
GQS_10180	ENOG4105D5P	Methylmalonyl-coA mutase
GQS_10200	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GQS_10220	ENOG4105C1J	atp-dependent rna helicase
GQS_10230	ENOG4105C1J	atp-dependent rna helicase
GQS_10240	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
GQS_10255	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GQS_10270	ENOG4107QMS	site-determining protein
GQS_10275	ENOG4107QX8	SPFH domain, Band 7 family protein
GQS_10310	ENOG4105E7W	lamb ycsf family protein
GQS_10315	ENOG4105P4J	Allophanate hydrolase, subunit 1
GQS_10330	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
GQS_10340	ENOG4105ECY	inositol monophosphatase
GQS_10345	ENOG4107ZXI	Rhomboid family
GQS_10350	ENOG4105DVT	helicase
GQS_10365	ENOG4105CN9	Peptidase m42 family protein
GQS_10375	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GQS_10380	ENOG4107R8N	Glycosyl transferase, family 2
GQS_10390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GQS_10410	ENOG4108TVJ	Nitroreductase
GQS_10420	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GQS_10430	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GQS_10445	ENOG4107RGD	Major Facilitator superfamily
GQS_10450	ENOG4105CD5	CoA-binding domain protein
GQS_10485	ENOG4105CSM	endonuclease III
GQS_10525	ENOG4105BZA	Phosphoglycerate kinase
GQS_10550	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GQS_10555	ENOG4105ECW	sulfate abc transporter
GQS_10600	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
GQS_10605	ENOG4108JJB	ABC transporter
GQS_10615	ENOG4105VKD	bioY protein
GQS_10630	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GQS_10650	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GQS_10665	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GQS_10700	ENOG4105C5S	asparaginyl-tRNA synthetase