locus-tag	class	description
GQS_00050	COG0402	S-adenosylhomocysteine deaminase activity
GQS_00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_00090	COG0631	protein serine/threonine phosphatase activity
GQS_00095	COG0515	serine threonine protein kinase
GQS_00095	COG2815	serine threonine protein kinase
GQS_00110	COG0631	protein serine/threonine phosphatase activity
GQS_00115	COG0515	serine threonine protein kinase
GQS_00115	COG2815	serine threonine protein kinase
GQS_00125	COG0515	serine threonine protein kinase
GQS_00125	COG2815	serine threonine protein kinase
GQS_00130	COG0515	serine threonine protein kinase
GQS_00130	COG2815	serine threonine protein kinase
GQS_00165	COG0515	serine threonine protein kinase
GQS_00165	COG2815	serine threonine protein kinase
GQS_00175	COG0175	sulfate reduction
GQS_00215	COG0105	UTP biosynthetic process
GQS_00225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQS_00230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_00235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS_00265	COG0419	ATPase involved in DNA repair
GQS_00265	COG0419	ATPase involved in DNA repair
GQS_00295	COG0084	hydrolase, TatD family'
GQS_00310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS_00315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS_00320	COG1201	RNA secondary structure unwinding
GQS_00330	COG0477	Major facilitator Superfamily
GQS_00345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_00370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQS_00380	COG1342	Belongs to the UPF0251 family
GQS_00480	COG0489	protein tyrosine kinase activity
GQS_00505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS_00520	COG2267	carboxylic ester hydrolase activity
GQS_00530	COG1830	Aldolase
GQS_00550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_00570	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQS_00575	COG1518	maintenance of DNA repeat elements
GQS_00605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS_00690	COG2033	superoxide reductase activity
GQS_00695	COG1773	rubredoxin
GQS_00700	COG1592	Rubrerythrin
GQS_00715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GQS_00720	COG0640	Transcriptional regulator
GQS_00725	COG2217	Heavy metal translocating P-type atpase
GQS_00730	COG0456	acetyltransferase
GQS_00740	COG2217	Heavy metal translocating P-type atpase
GQS_00760	COG2226	methyltransferase
GQS_00780	COG0450	alkyl hydroperoxide reductase
GQS_00785	COG0243	molybdopterin cofactor binding
GQS_00840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQS_00895	COG0477	Major facilitator Superfamily
GQS_00900	COG0312	modulator of DNA gyrase
GQS_00925	COG1794	racemase activity, acting on amino acids and derivatives
GQS_00935	COG0668	transmembrane transport
GQS_00945	COG1993	acr, cog1993
GQS_00950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQS_00970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS_00980	COG0563	adenylate kinase activity
GQS_00995	COG0011	TIGRFAM Protein of
GQS_01000	COG2226	methyltransferase
GQS_01015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS_01025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_01035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQS_01045	COG1121	(ABC) transporter
GQS_01085	COG1401	restriction endodeoxyribonuclease activity
GQS_01100	COG1469	GTP cyclohydrolase I activity
GQS_01115	COG1078	dGTPase activity
GQS_01120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS_01130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS_01135	COG0051	transcription antitermination factor activity, RNA binding
GQS_01145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQS_01165	COG0732	type I restriction modification DNA specificity domain
GQS_01180	COG2414	aldehyde ferredoxin oxidoreductase
GQS_01185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_01210	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
GQS_01250	COG1121	(ABC) transporter
GQS_01255	COG1111	helicase
GQS_01255	COG1205	dead DEAH box helicase
GQS_01260	COG1739	Uncharacterized protein family UPF0029
GQS_01290	COG1216	Glycosyl transferase, family 2
GQS_01295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQS_01305	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQS_01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_01335	COG0315	cyclic pyranopterin monophosphate synthase activity
GQS_01345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQS_01355	COG0459	protein refolding
GQS_01370	COG1028	Short-chain dehydrogenase reductase Sdr
GQS_01375	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GQS_01380	COG0277	FAD linked oxidase domain protein
GQS_01390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQS_01430	COG2819	hydrolase of the alpha beta superfamily
GQS_01445	COG1078	dGTPase activity
GQS_01470	COG0303	'Molybdopterin
GQS_01505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQS_01515	COG0746	molybdenum cofactor guanylyltransferase activity
GQS_01520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQS_01530	COG1573	uracil-dna glycosylase
GQS_01535	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GQS_01540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS_01555	COG0714	Associated with various cellular activities
GQS_01570	COG2226	methyltransferase
GQS_01575	COG0525	valine-tRNA ligase activity
GQS_01590	COG1525	nuclease
GQS_01595	COG2264	protein methyltransferase activity
GQS_01610	COG0312	modulator of DNA gyrase
GQS_01620	COG1794	racemase activity, acting on amino acids and derivatives
GQS_01625	COG0598	Magnesium transport protein CorA
GQS_01630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS_01640	COG0012	GTP binding
GQS_01650	COG1522	sequence-specific DNA binding
GQS_01655	COG0163	prenyltransferase activity
GQS_01680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQS_01690	COG1918	ferrous iron import across plasma membrane
GQS_01690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQS_01705	COG0482	sulfurtransferase activity
GQS_01730	COG0006	proline dipeptidase activity
GQS_01745	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
GQS_01755	COG0534	Mate efflux family protein
GQS_01770	COG0423	glycine-tRNA ligase activity
GQS_01780	COG1872	DUF167
GQS_01795	COG1546	Belongs to the CinA family
GQS_01795	COG1058	Belongs to the CinA family
GQS_01810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_01820	COG2096	Adenosyltransferase
GQS_01830	COG2814	Major facilitator Superfamily
GQS_01860	COG2409	Drug exporters of the RND superfamily
GQS_01870	COG1363	Peptidase, m42
GQS_01980	COG1505	serine-type exopeptidase activity
GQS_01990	COG4145	pantothenate transmembrane transporter activity
GQS_02005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS_02015	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
GQS_02020	COG1992	Thiamine-phosphate synthase
GQS_02020	COG0351	phosphomethylpyrimidine kinase
GQS_02050	COG0215	cysteine-tRNA ligase activity
GQS_02090	COG1744	ABC transporter substrate-binding protein PnrA-like
GQS_02110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQS_02125	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_02125	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQS_02130	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_02140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQS_02140	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_02145	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_02170	COG0720	synthase
GQS_02200	COG0730	response to heat
GQS_02210	COG0730	response to heat
GQS_02230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS_02235	COG0442	prolyl-tRNA aminoacylation
GQS_02245	COG2192	nodulation
GQS_02260	COG0436	Aminotransferase
GQS_02270	COG0501	Belongs to the peptidase M48B family
GQS_02275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQS_02285	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
GQS_02295	COG1515	deoxyribonuclease V activity
GQS_02330	COG1476	TRANSCRIPTIONal
GQS_02335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQS_02350	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GQS_02355	COG3259	Nickel-dependent hydrogenase
GQS_02365	COG0437	4 iron, 4 sulfur cluster binding
GQS_02380	COG2111	Na H antiporter
GQS_02380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_02390	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_02420	COG3260	NADH ubiquinone oxidoreductase 20
GQS_02425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_02430	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GQS_02430	COG3261	NADH dehydrogenase
GQS_02435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS_02440	COG0651	ATP synthesis coupled electron transport
GQS_02445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_02450	COG0437	4 iron, 4 sulfur cluster binding
GQS_02455	COG0243	molybdopterin cofactor binding
GQS_02470	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
GQS_02475	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GQS_02495	COG0719	Fe-S assembly protein
GQS_02500	COG0396	ATPase activity
GQS_02530	COG1694	Mazg nucleotide pyrophosphohydrolase
GQS_02535	COG1522	sequence-specific DNA binding
GQS_02540	COG1836	PFAM Integral membrane protein DUF92
GQS_02545	COG0301	tRNA thio-modification
GQS_02545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS_02640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS_02650	COG0018	arginyl-trna synthetase
GQS_02680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS_02700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_02710	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_02715	COG2212	antiporter activity
GQS_02720	COG1320	monovalent cation:proton antiporter activity
GQS_02730	COG2111	Na H antiporter
GQS_02730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_02735	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_02740	COG0651	ATP synthesis coupled electron transport
GQS_02755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_02760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_02760	COG0649	NAD binding
GQS_02760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_02765	COG0649	NAD binding
GQS_02795	COG1522	sequence-specific DNA binding
GQS_02815	COG1151	hydroxylamine reductase activity
GQS_02850	COG1881	PFAM PEBP family protein
GQS_02880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_02885	COG0602	queuosine metabolic process
GQS_02890	COG0640	Transcriptional regulator
GQS_02955	COG0359	binds to the 23S rRNA
GQS_02955	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GQS_02975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_02975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_03000	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GQS_03015	COG1757	Na H antiporter
GQS_03025	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GQS_03035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQS_03075	COG0010	Belongs to the arginase family
GQS_03090	COG0475	glutathione-regulated potassium exporter activity
GQS_03100	COG0038	chloride channel
GQS_03110	COG1085	galactose-1-phosphate uridylyltransferase
GQS_03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQS_03125	COG0438	transferase activity, transferring glycosyl groups
GQS_03195	COG0252	asparaginase activity
GQS_03230	COG2894	cell division
GQS_03235	COG1063	alcohol dehydrogenase
GQS_03240	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQS_03255	COG0101	tRNA pseudouridine synthase activity
GQS_03260	COG0556	nucleotide-excision repair
GQS_03270	COG1131	(ABC) transporter
GQS_03295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQS_03300	COG0628	permease
GQS_03350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQS_03365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS_03410	COG1122	ATPase activity
GQS_03415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQS_03420	COG0024	Methionine aminopeptidase
GQS_03425	COG0516	GMP reductase activity
GQS_03425	COG0517	IMP dehydrogenase activity
GQS_03435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQS_03450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_03470	COG0504	CTP synthase activity
GQS_03505	COG0585	pseudouridine synthase activity
GQS_03520	COG0017	Asparaginyl-tRNA synthetase
GQS_03530	COG1418	mRNA catabolic process
GQS_03545	COG0546	phosphoglycolate phosphatase activity
GQS_03555	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GQS_03595	COG1110	DNA topoisomerase II activity
GQS_03615	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_03615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_03615	COG1042	CoA-binding domain protein
GQS_03655	COG1518	maintenance of DNA repeat elements
GQS_03665	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQS_03690	COG0644	oxidoreductase
GQS_03695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS_03730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS_03745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQS_03750	COG0081	regulation of translation
GQS_03765	COG0717	Belongs to the dCTP deaminase family
GQS_03795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS_03805	COG0058	SHG alpha-glucan phosphorylase activity
GQS_03825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQS_03855	COG2814	Major facilitator Superfamily
GQS_03860	COG0584	glycerophosphoryl diester phosphodiesterase
GQS_03865	COG0584	glycerophosphoryl diester phosphodiesterase
GQS_03875	COG0579	oxidoreductase
GQS_03935	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_03940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_03950	COG0085	RNA polymerase activity
GQS_03955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS_03960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS_03980	COG0049	tRNA binding
GQS_03995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQS_04015	COG0436	Aminotransferase
GQS_04040	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_04075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GQS_04075	COG0662	Cupin 2, conserved barrel domain protein
GQS_04085	COG2140	Oxalate decarboxylase
GQS_04115	COG4412	M6 family metalloprotease domain protein
GQS_04115	COG3291	Pkd domain containing protein
GQS_04140	COG0798	PFAM Bile acid sodium symporter
GQS_04180	COG0719	Fe-S assembly protein
GQS_04185	COG1137	ATPase activity
GQS_04210	COG2414	aldehyde ferredoxin oxidoreductase
GQS_04220	COG0489	protein tyrosine kinase activity
GQS_04235	COG0298	carbon dioxide binding
GQS_04240	COG0409	Hydrogenase expression formation protein
GQS_04245	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GQS_04270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQS_04280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS_04290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_04290	COG0731	radical SAM domain protein
GQS_04305	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS_04320	COG1404	Belongs to the peptidase S8 family
GQS_04345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS_04345	COG0574	Belongs to the PEP-utilizing enzyme family
GQS_04350	COG0534	Mate efflux family protein
GQS_04360	COG0534	Mate efflux family protein
GQS_04365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQS_04370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQS_04385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQS_04390	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQS_04405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS_04410	COG0733	neurotransmitter:sodium symporter activity
GQS_04425	COG0347	Belongs to the P(II) protein family
GQS_04430	COG1543	Belongs to the glycosyl hydrolase 57 family
GQS_04445	COG0864	Transcriptional regulator
GQS_04500	COG0006	proline dipeptidase activity
GQS_04510	COG0495	leucyl-tRNA aminoacylation
GQS_04520	COG0477	Major facilitator Superfamily
GQS_04525	COG0142	geranyltranstransferase activity
GQS_04535	COG1304	FMN binding
GQS_04540	COG2414	aldehyde ferredoxin oxidoreductase
GQS_04545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_04550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_04570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQS_04580	COG1355	regulation of microtubule-based process
GQS_04585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQS_04590	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GQS_04595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS_04600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQS_04615	COG1160	GTP binding
GQS_04625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQS_04640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS_04650	COG1522	sequence-specific DNA binding
GQS_04670	COG0052	Belongs to the universal ribosomal protein uS2 family
GQS_04690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQS_04695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQS_04710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQS_04715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQS_04720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS_04725	COG2813	Specifically methylates the guanine in position
GQS_04735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQS_04745	COG1102	Psort location Cytoplasmic, score
GQS_04770	COG0200	Binds to the 23S rRNA
GQS_04775	COG1841	ribosomal large subunit assembly
GQS_04780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQS_04785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQS_04800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQS_04805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQS_04815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS_04825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQS_04830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQS_04835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQS_04845	COG0023	Translation Initiation Factor
GQS_04850	COG0255	Belongs to the universal ribosomal protein uL29 family
GQS_04855	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQS_04865	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQS_04870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS_04875	COG0089	rRNA binding
GQS_04880	COG0088	Forms part of the polypeptide exit tunnel
GQS_04885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQS_04920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQS_04935	COG0017	Asparaginyl-tRNA synthetase
GQS_04940	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_04980	COG0543	2 iron, 2 sulfur cluster binding
GQS_04990	COG3259	Nickel-dependent hydrogenase
GQS_05015	COG0430	RNA-3'-phosphate cyclase activity
GQS_05050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS_05060	COG0511	ligase activity, forming carbon-carbon bonds
GQS_05060	COG5016	pyruvate
GQS_05065	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GQS_05070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQS_05070	COG0517	IMP dehydrogenase activity
GQS_05105	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQS_05110	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_05190	COG1335	isochorismatase
GQS_05200	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_05200	COG2050	protein possibly involved in aromatic compounds catabolism
GQS_05210	COG1695	Transcriptional regulator
GQS_05230	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_05270	COG0417	DNA replication proofreading
GQS_05280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS_05280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_05285	COG2078	PFAM AMMECR1 domain protein
GQS_05290	COG0011	TIGRFAM Protein of
GQS_05315	COG1178	ABC-type Fe3 transport system permease component
GQS_05320	COG3842	ATPase activity
GQS_05340	COG2252	PERMEase
GQS_05375	COG0109	protoheme IX farnesyltransferase activity
GQS_05385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQS_05390	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQS_05415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS_05450	COG0668	transmembrane transport
GQS_05465	COG2264	protein methyltransferase activity
GQS_05485	COG0393	Putative heavy-metal-binding
GQS_05550	COG2234	aminopeptidase activity
GQS_05650	COG2264	protein methyltransferase activity
GQS_05720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS_05720	COG0519	Catalyzes the synthesis of GMP from XMP
GQS_05735	COG0519	Catalyzes the synthesis of GMP from XMP
GQS_05735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS_05745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQS_05755	COG0047	phosphoribosylformylglycinamidine synthase activity
GQS_05770	COG0151	Belongs to the GarS family
GQS_05775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQS_05780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQS_05785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQS_05795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS_05800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GQS_05815	COG3383	formate dehydrogenase (NAD+) activity
GQS_05820	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GQS_05825	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GQS_05835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQS_05840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQS_05850	COG0517	IMP dehydrogenase activity
GQS_05850	COG0516	GMP reductase activity
GQS_05880	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
GQS_05890	COG1120	ATPase activity
GQS_05960	COG0438	transferase activity, transferring glycosyl groups
GQS_05960	COG0297	glycogen (starch) synthase activity
GQS_05995	COG1287	oligosaccharyl transferase activity
GQS_06000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQS_06030	COG0714	Associated with various cellular activities
GQS_06075	COG0438	transferase activity, transferring glycosyl groups
GQS_06085	COG0438	transferase activity, transferring glycosyl groups
GQS_06105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQS_06110	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GQS_06120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GQS_06195	COG0297	glycogen (starch) synthase activity
GQS_06200	COG1378	Sugar-specific transcriptional regulator TrmB
GQS_06215	COG1175	transmembrane transport
GQS_06220	COG3833	ABC-type maltose transport systems, permease component
GQS_06230	COG3842	ATPase activity
GQS_06240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS_06250	COG1234	tRNA 3'-trailer cleavage
GQS_06255	COG1297	OPT oligopeptide transporter protein
GQS_06265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS_06285	COG0022	dehydrogenase e1 component
GQS_06290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS_06305	COG0022	dehydrogenase e1 component
GQS_06310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS_06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS_06320	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS_06325	COG3199	ATP-NAD kinase
GQS_06330	COG0095	Lipoate-protein ligase
GQS_06335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS_06355	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQS_06385	COG0174	glutamine synthetase
GQS_06405	COG4608	Belongs to the ABC transporter superfamily
GQS_06410	COG0444	Belongs to the ABC transporter superfamily
GQS_06415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS_06420	COG0601	transmembrane transport
GQS_06440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS_06475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_06480	COG1394	ATPase activity, coupled to movement of substances
GQS_06485	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
GQS_06490	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GQS_06505	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
GQS_06515	COG1269	ATP hydrolysis coupled proton transport
GQS_06525	COG0569	domain protein
GQS_06530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS_06535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS_06550	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQS_06595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQS_06615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_06695	COG0475	glutathione-regulated potassium exporter activity
GQS_06700	COG0475	glutathione-regulated potassium exporter activity
GQS_06705	COG0517	IMP dehydrogenase activity
GQS_06705	COG0516	GMP reductase activity
GQS_06710	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GQS_06720	COG0037	tRNA processing
GQS_06735	COG1449	Belongs to the glycosyl hydrolase 57 family
GQS_06760	COG4651	solute:proton antiporter activity
GQS_06760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS_06765	COG0076	glutamate decarboxylase activity
GQS_06770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GQS_06780	COG2046	Belongs to the sulfate adenylyltransferase family
GQS_06800	COG0730	response to heat
GQS_06810	COG3119	arylsulfatase activity
GQS_06835	COG3119	arylsulfatase activity
GQS_06840	COG0463	Glycosyl transferase, family 2
GQS_06840	COG1216	Glycosyl transferase, family 2
GQS_06845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS_06850	COG0037	tRNA processing
GQS_06885	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GQS_06890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS_06900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GQS_06920	COG0714	Associated with various cellular activities
GQS_06945	COG1047	Peptidyl-prolyl cis-trans
GQS_06980	COG1160	GTP binding
GQS_06995	COG0116	Belongs to the methyltransferase superfamily
GQS_06995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS_07015	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS_07070	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_07070	COG1042	CoA-binding domain protein
GQS_07070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_07075	COG0640	Transcriptional regulator
GQS_07100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GQS_07100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQS_07110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQS_07110	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GQS_07120	COG0402	S-adenosylhomocysteine deaminase activity
GQS_07130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQS_07180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS_07245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQS_07255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS_07270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQS_07270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_07310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQS_07320	COG0314	molybdopterin synthase activity
GQS_07340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQS_07345	COG1522	sequence-specific DNA binding
GQS_07370	COG0148	phosphopyruvate hydratase activity
GQS_07385	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQS_07400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GQS_07405	COG0492	ferredoxin-NADP+ reductase activity
GQS_07420	COG2255	four-way junction helicase activity
GQS_07450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS_07465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_07470	COG3260	NADH ubiquinone oxidoreductase 20
GQS_07480	COG0651	ATP synthesis coupled electron transport
GQS_07485	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_07490	COG2111	Na H antiporter
GQS_07505	COG1320	monovalent cation:proton antiporter activity
GQS_07510	COG2212	antiporter activity
GQS_07520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_07525	COG0650	Formate hydrogenlyase subunit 4
GQS_07535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_07540	COG3260	NADH ubiquinone oxidoreductase 20
GQS_07550	COG0651	ATP synthesis coupled electron transport
GQS_07575	COG1320	monovalent cation:proton antiporter activity
GQS_07580	COG2212	antiporter activity
GQS_07585	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_07595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_07605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS_07635	COG0306	phosphate transporter
GQS_07685	COG0823	Involved in the tonB-independent uptake of proteins
GQS_07685	COG1506	peptidase
GQS_07685	COG4946	Tricorn protease homolog
GQS_07740	COG0681	Belongs to the peptidase S26 family
GQS_07745	COG0095	Lipoate-protein ligase
GQS_07785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQS_07795	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GQS_07805	COG0235	Class ii aldolase
GQS_07830	COG1346	cytolysis
GQS_07835	COG1380	Effector of murein hydrolase LrgA
GQS_07850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_07860	COG1573	uracil-dna glycosylase
GQS_07870	COG1757	Na H antiporter
GQS_07890	COG1793	dna ligase
GQS_07900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQS_07905	COG2894	cell division
GQS_07920	COG1522	sequence-specific DNA binding
GQS_07930	COG1980	fructose-bisphosphate aldolase activity
GQS_07940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS_08025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS_08045	COG1254	Belongs to the acylphosphatase family
GQS_08055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS_08080	COG0489	protein tyrosine kinase activity
GQS_08085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS_08105	COG0746	molybdenum cofactor guanylyltransferase activity
GQS_08110	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_08115	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_08125	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_08130	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_08145	COG0306	phosphate transporter
GQS_08150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS_08180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQS_08190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQS_08195	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS_08195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS_08210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS_08250	COG0312	modulator of DNA gyrase
GQS_08290	COG0714	Associated with various cellular activities
GQS_08305	COG0434	BtpA family
GQS_08345	COG1988	membrane-bound metal-dependent
GQS_08365	COG0237	dephospho-CoA kinase activity
GQS_08380	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GQS_08385	COG0540	Belongs to the ATCase OTCase family
GQS_08395	COG0432	Pfam Uncharacterised protein family UPF0047
GQS_08415	COG0667	Aldo Keto reductase
GQS_08420	COG1234	tRNA 3'-trailer cleavage
GQS_08430	COG0442	prolyl-tRNA aminoacylation
GQS_08435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_08465	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GQS_08470	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS_08475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS_08485	COG1214	PFAM Peptidase M22, glycoprotease
GQS_08485	COG0456	acetyltransferase
GQS_08500	COG0156	8-amino-7-oxononanoate synthase activity
GQS_08505	COG2255	four-way junction helicase activity
GQS_08535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_08560	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQS_08575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQS_08600	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GQS_08620	COG1446	asparaginase
GQS_08630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQS_08650	COG2814	Major facilitator Superfamily
GQS_08655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_08665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQS_08680	COG2131	deaminase
GQS_08685	COG0501	Belongs to the peptidase M48B family
GQS_08710	COG0543	2 iron, 2 sulfur cluster binding
GQS_08715	COG0493	'glutamate synthase
GQS_08715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_08735	COG1028	Short-chain dehydrogenase reductase Sdr
GQS_08745	COG1141	Ferredoxin
GQS_08750	COG2151	metal-sulfur cluster biosynthetic enzyme
GQS_08770	COG1404	Belongs to the peptidase S8 family
GQS_08780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GQS_08785	COG0167	dihydroorotate dehydrogenase activity
GQS_08805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS_08845	COG2723	6-phospho-beta-galactosidase activity
GQS_08860	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQS_08875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS_08910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_08920	COG0693	protein deglycase activity
GQS_08960	COG2095	MarC family integral membrane protein
GQS_08965	COG1765	OsmC-like protein
GQS_08975	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQS_08980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS_08985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_09005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS_09080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS_09085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQS_09135	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS_09155	COG0440	acetolactate synthase activity
GQS_09160	COG0651	ATP synthesis coupled electron transport
GQS_09190	COG2212	antiporter activity
GQS_09195	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_09200	COG0509	glycine decarboxylation via glycine cleavage system
GQS_09215	COG0493	'glutamate synthase
GQS_09215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_09220	COG0543	2 iron, 2 sulfur cluster binding
GQS_09250	COG0747	negative chemotaxis
GQS_09255	COG0601	transmembrane transport
GQS_09265	COG0444	Belongs to the ABC transporter superfamily
GQS_09270	COG4608	Belongs to the ABC transporter superfamily
GQS_09305	COG1131	(ABC) transporter
GQS_09315	COG1476	TRANSCRIPTIONal
GQS_09355	COG2119	membrane
GQS_09375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS_09380	COG1192	Involved in chromosome partitioning
GQS_09390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GQS_09390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQS_09400	COG0284	orotidine-5'-phosphate decarboxylase activity
GQS_09430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQS_09430	COG1213	nucleotidyl transferase
GQS_09445	COG1131	(ABC) transporter
GQS_09490	COG1850	ribulose-bisphosphate carboxylase activity
GQS_09495	COG1435	thymidine kinase activity
GQS_09540	COG0463	Glycosyl transferase, family 2
GQS_09550	COG0673	inositol 2-dehydrogenase activity
GQS_09570	COG3842	ATPase activity
GQS_09580	COG2379	hydroxypyruvate reductase
GQS_09610	COG1832	CoA-binding protein
GQS_09635	COG1160	GTP binding
GQS_09655	COG0725	ABC transporter, periplasmic molybdate-binding protein
GQS_09660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GQS_09665	COG3842	ATPase activity
GQS_09675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQS_09680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GQS_09695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQS_09700	COG0560	Phosphoserine phosphatase
GQS_09765	COG1051	belongs to the nudix hydrolase family
GQS_09765	COG1056	cytidyltransferase-related domain
GQS_09780	COG0456	acetyltransferase
GQS_09805	COG2226	methyltransferase
GQS_09830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_09865	COG0778	Nitroreductase
GQS_09870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GQS_09880	COG4608	Belongs to the ABC transporter superfamily
GQS_09885	COG0444	Belongs to the ABC transporter superfamily
GQS_09890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS_09900	COG0747	negative chemotaxis
GQS_09950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_09955	COG0071	Belongs to the small heat shock protein (HSP20) family
GQS_09965	COG1793	dna ligase
GQS_09965	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQS_10055	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_10055	COG1042	CoA-binding domain protein
GQS_10055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_10075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_10095	COG0303	'Molybdopterin
GQS_10100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS_10120	COG0009	L-threonylcarbamoyladenylate synthase
GQS_10135	COG0367	asparagine synthase
GQS_10145	COG2894	cell division
GQS_10150	COG4956	integral membrane protein (PIN domain superfamily)
GQS_10165	COG0424	maF-like protein
GQS_10175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GQS_10180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_10180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_10200	COG1196	nuclear chromosome segregation
GQS_10220	COG0513	Belongs to the DEAD box helicase family
GQS_10240	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GQS_10255	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GQS_10270	COG2894	cell division
GQS_10275	COG0330	HflC and HflK could
GQS_10290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GQS_10310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GQS_10315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GQS_10320	COG1984	allophanate hydrolase subunit 2
GQS_10330	COG1454	alcohol dehydrogenase
GQS_10340	COG0483	inositol monophosphate 1-phosphatase activity
GQS_10345	COG0457	Tetratricopeptide repeat
GQS_10345	COG0705	Rhomboid family
GQS_10350	COG1199	ATP-dependent helicase activity
GQS_10375	COG1489	DNA binding
GQS_10380	COG1215	transferase activity, transferring glycosyl groups
GQS_10410	COG0778	Nitroreductase
GQS_10420	COG0301	tRNA thio-modification
GQS_10430	COG0301	tRNA thio-modification
GQS_10450	COG1042	CoA-binding domain protein
GQS_10450	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_10450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_10485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQS_10525	COG0126	phosphoglycerate kinase activity
GQS_10550	COG3842	ATPase activity
GQS_10555	COG4208	sulfate ABC transporter
GQS_10575	COG1522	sequence-specific DNA binding
GQS_10600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GQS_10605	COG1122	ATPase activity
GQS_10615	COG1268	BioY protein
GQS_10630	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQS_10650	COG4946	Tricorn protease homolog
GQS_10650	COG1506	peptidase
GQS_10650	COG0823	Involved in the tonB-independent uptake of proteins
GQS_10665	COG1444	tRNA N-acetyltransferase activity
GQS_10700	COG0017	Asparaginyl-tRNA synthetase