TAM4_1536 86a0a0056683c61f9d046a10831bc18d 270 Gene3D G3DSA:3.20.20.20 2 270 1.5E-87 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TAM4_1536 86a0a0056683c61f9d046a10831bc18d 270 SUPERFAMILY SSF51717 8 269 3.14E-78 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TAM4_1536 86a0a0056683c61f9d046a10831bc18d 270 Pfam PF00809 Pterin binding enzyme 14 252 8.9E-58 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TAM4_1536 86a0a0056683c61f9d046a10831bc18d 270 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 265 1.2E-69 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 Gene3D G3DSA:3.50.50.60 18 316 4.7E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 Gene3D G3DSA:3.50.50.60 126 269 4.7E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 SUPERFAMILY SSF51971 14 270 7.06E-56 T 23-10-2018 TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 311 2.3E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 2.1E-15 T 23-10-2018 TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 2.1E-15 T 23-10-2018 TAM4_608 23bc4a8f410a94e03aa62f73576408c5 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 2.1E-15 T 23-10-2018 TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.152 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 Gene3D G3DSA:3.90.1140.10 1 184 1.7E-66 T 23-10-2018 TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.3E-54 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 Pfam PF02834 LigT like Phosphoesterase 98 174 3.0E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 Pfam PF02834 LigT like Phosphoesterase 7 91 2.2E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TAM4_1030 8c9e1e09907f56d788c4c779859cbd25 184 SUPERFAMILY SSF55144 1 182 6.8E-46 T 23-10-2018 IPR009097 Cyclic phosphodiesterase TAM4_170 a6b9f8f4dc452686d0057d17bc5bcf4d 402 SUPERFAMILY SSF53743 1 281 1.91E-37 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 TAM4_1392 8ab61b83c230c18531a4b39180b9d4d0 66 Gene3D G3DSA:4.10.1150.10 1 58 1.7E-11 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_1392 8ab61b83c230c18531a4b39180b9d4d0 66 Pfam PF01954 Protein of unknown function DUF104 1 46 9.4E-14 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_1392 8ab61b83c230c18531a4b39180b9d4d0 66 SUPERFAMILY SSF141694 1 42 1.1E-12 T 23-10-2018 TAM4_1102 3a293a629577e8764ab848bcaea59341 241 Gene3D G3DSA:3.40.50.300 5 200 4.8E-32 T 23-10-2018 TAM4_1102 3a293a629577e8764ab848bcaea59341 241 SUPERFAMILY SSF52540 18 211 9.6E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1102 3a293a629577e8764ab848bcaea59341 241 SMART SM00382 41 179 7.9E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1102 3a293a629577e8764ab848bcaea59341 241 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 169 2.0E-23 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_2119 beb4d38952bd7d2d98271563d76a3f24 272 SMART SM00849 19 243 3.1E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2119 beb4d38952bd7d2d98271563d76a3f24 272 SUPERFAMILY SSF56281 5 272 4.98E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2119 beb4d38952bd7d2d98271563d76a3f24 272 Pfam PF00753 Metallo-beta-lactamase superfamily 20 101 4.6E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2119 beb4d38952bd7d2d98271563d76a3f24 272 Gene3D G3DSA:3.60.15.10 1 272 3.4E-85 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_305 963c5f81d6fcf19042dee343f47373c1 84 Gene3D G3DSA:3.30.70.920 4 75 6.3E-22 T 23-10-2018 TAM4_305 963c5f81d6fcf19042dee343f47373c1 84 Pfam PF01037 Lrp/AsnC ligand binding domain 10 76 1.2E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_305 963c5f81d6fcf19042dee343f47373c1 84 SUPERFAMILY SSF54909 4 76 1.29E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_219 cec663e130b05a84c1d70cc69e32fe96 114 Gene3D G3DSA:3.10.530.10 46 112 8.5E-16 T 23-10-2018 IPR036593 CPE0013-like superfamily TAM4_219 cec663e130b05a84c1d70cc69e32fe96 114 SUPERFAMILY SSF53706 2 51 4.71E-7 T 23-10-2018 TAM4_219 cec663e130b05a84c1d70cc69e32fe96 114 SUPERFAMILY SSF160148 46 113 7.59E-19 T 23-10-2018 IPR036593 CPE0013-like superfamily TAM4_219 cec663e130b05a84c1d70cc69e32fe96 114 Pfam PF07892 Protein of unknown function (DUF1667) 34 112 5.8E-27 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 TAM4_1412 4ce1bf4493b191bfdcf1dd0ae1341a8f 278 Pfam PF01513 ATP-NAD kinase 2 261 7.7E-67 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TAM4_1412 4ce1bf4493b191bfdcf1dd0ae1341a8f 278 Gene3D G3DSA:3.40.50.10330 20 267 3.9E-69 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TAM4_1412 4ce1bf4493b191bfdcf1dd0ae1341a8f 278 Gene3D G3DSA:2.60.200.30 121 254 3.9E-69 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TAM4_1412 4ce1bf4493b191bfdcf1dd0ae1341a8f 278 SUPERFAMILY SSF111331 3 265 1.44E-71 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TAM4_1412 4ce1bf4493b191bfdcf1dd0ae1341a8f 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 29.765 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:2.170.16.10 1080 1205 4.1E-14 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1079 1167 3.8E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 495 590 1.3E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1445 1467 1.8E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1005 1029 1.8E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 2.7E-12 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 5.1E-33 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF53098 1 347 6.64E-88 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.90.1600.20 378 444 4.2E-13 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF14890 Intein splicing domain 1089 1466 3.7E-21 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 65 492 3.5E-95 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 1466 1671 3.0E-72 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF14890 Intein splicing domain 501 1028 1.6E-53 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF55608 1302 1415 3.4E-19 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.10.28.10 765 933 9.8E-229 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.10.28.10 1220 1394 1.8E-25 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SMART SM00486 133 545 1.7E-101 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:1.10.132.60 1533 1699 1.0E-62 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.30.1490.210 934 986 9.8E-229 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.90.1600.10 1465 1532 1.6E-16 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.90.1600.10 1027 1079 4.2E-13 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.30.342.10 3 366 9.9E-173 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 769 781 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 578 591 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 1443 1460 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 1320 1332 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 1461 1470 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 PRINTS PR00379 Intein signature 1350 1365 1.0E-27 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF14528 LAGLIDADG-like domain 865 923 2.6E-6 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF14528 LAGLIDADG-like domain 1320 1401 1.0E-14 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF51294 1078 1467 1.06E-24 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF56672 349 493 2.61E-43 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:2.170.16.10 505 1026 9.8E-229 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:3.30.420.10 131 347 9.9E-173 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF56672 1027 1683 7.05E-76 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SMART SM00306 1076 1192 2.9E-19 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SMART SM00306 490 615 4.6E-28 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF51294 492 1029 9.03E-38 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:2.170.16.10 1418 1464 3.2E-9 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:1.10.287.690 447 493 5.0E-18 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Gene3D G3DSA:1.10.10.1010 619 764 9.8E-229 T 23-10-2018 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SUPERFAMILY SSF55608 848 938 9.64E-18 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SMART SM00305 986 1034 1.2E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 SMART SM00305 1430 1472 4.5E-11 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF00136 DNA polymerase family B 1467 1673 1.1E-30 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF00136 DNA polymerase family B 1028 1069 8.1E-7 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1747 dbe9f48416da2795647fc1b3d7f3e29e 1699 Pfam PF00136 DNA polymerase family B 352 493 1.1E-29 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Gene3D G3DSA:1.10.10.770 319 433 2.3E-39 T 23-10-2018 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Gene3D G3DSA:1.10.10.350 434 525 3.3E-25 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Gene3D G3DSA:1.10.10.860 271 318 5.8E-23 T 23-10-2018 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Pfam PF01921 tRNA synthetases class I (K) 3 362 8.2E-141 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Gene3D G3DSA:3.40.50.620 4 270 4.6E-112 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Gene3D G3DSA:2.30.30.300 170 213 4.6E-112 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 522 2.0E-165 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 SUPERFAMILY SSF52374 3 319 3.07E-68 T 23-10-2018 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 525 38.752 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TAM4_101 b6c42387177e02d8ddcebc0ba9675f54 525 SUPERFAMILY SSF48163 323 522 6.41E-49 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TAM4_2371 96e4426e8202d380bde09800f2da6550 199 Pfam PF00733 Asparagine synthase 8 63 1.7E-4 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TAM4_2371 96e4426e8202d380bde09800f2da6550 199 Gene3D G3DSA:3.40.50.620 1 199 2.9E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_2371 96e4426e8202d380bde09800f2da6550 199 SUPERFAMILY SSF52402 1 152 9.04E-24 T 23-10-2018 TAM4_823 eafe8aa74fc0a93737b7c9341dba644f 122 Pfam PF03874 RNA polymerase Rpb4 12 119 1.7E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 TAM4_823 eafe8aa74fc0a93737b7c9341dba644f 122 Gene3D G3DSA:1.10.150.80 55 122 3.5E-29 T 23-10-2018 TAM4_823 eafe8aa74fc0a93737b7c9341dba644f 122 PIRSF PIRSF005053 1 120 3.1E-31 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) TAM4_823 eafe8aa74fc0a93737b7c9341dba644f 122 Gene3D G3DSA:1.10.287.420 1 54 2.6E-34 T 23-10-2018 TAM4_823 eafe8aa74fc0a93737b7c9341dba644f 122 SUPERFAMILY SSF47819 1 115 3.75E-25 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 SUPERFAMILY SSF54570 34 117 1.1E-30 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 Gene3D G3DSA:3.30.860.20 2 133 1.5E-54 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 Pfam PF00203 Ribosomal protein S19 35 116 1.9E-35 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 1.1E-67 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 PIRSF PIRSF002144 1 133 1.7E-40 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.538 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 1.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 1.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_254 f56c924d1fa9ff4d7ca0f32e19eba3fc 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 1.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1549 d36378244aaa7b7532016060be07de84 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 184 1.3E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 Gene3D G3DSA:3.40.50.1000 6 188 4.3E-31 T 23-10-2018 IPR023214 HAD superfamily TAM4_1549 d36378244aaa7b7532016060be07de84 227 SUPERFAMILY SSF56784 1 216 3.56E-41 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1549 d36378244aaa7b7532016060be07de84 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 189 9.7E-26 T 23-10-2018 TAM4_1549 d36378244aaa7b7532016060be07de84 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 60 188 9.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1549 d36378244aaa7b7532016060be07de84 227 Gene3D G3DSA:1.10.150.240 17 86 4.3E-31 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TAM4_2343 63e86ddf26baad91d34f3adcae824bd1 92 PIRSF PIRSF004604 1 92 5.9E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_2343 63e86ddf26baad91d34f3adcae824bd1 92 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 91 5.0E-29 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_2343 63e86ddf26baad91d34f3adcae824bd1 92 Gene3D G3DSA:3.30.2320.10 1 92 1.3E-26 T 23-10-2018 TAM4_2343 63e86ddf26baad91d34f3adcae824bd1 92 Pfam PF08967 Domain of unknown function (DUF1884) 2 91 2.4E-38 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_2343 63e86ddf26baad91d34f3adcae824bd1 92 SUPERFAMILY SSF111057 1 91 5.49E-32 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TAM4_1940 7eb1b191dd8b9ba5c91fba4fba0bf6e0 384 Gene3D G3DSA:1.10.287.70 294 384 4.2E-14 T 23-10-2018 TAM4_1940 7eb1b191dd8b9ba5c91fba4fba0bf6e0 384 SUPERFAMILY SSF81324 297 383 4.84E-16 T 23-10-2018 TAM4_1940 7eb1b191dd8b9ba5c91fba4fba0bf6e0 384 Pfam PF07885 Ion channel 315 383 1.3E-12 T 23-10-2018 IPR013099 Potassium channel domain TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 SMART SM00670 2 115 1.3E-23 T 23-10-2018 IPR002716 PIN domain TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 Gene3D G3DSA:3.40.50.1010 1 127 2.9E-33 T 23-10-2018 TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 SUPERFAMILY SSF88723 1 132 5.61E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 SUPERFAMILY SSF54814 465 520 2.94E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 Pfam PF00437 Type II/IV secretion system protein 213 370 1.7E-9 T 23-10-2018 IPR001482 Type II/IV secretion system protein TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 Gene3D G3DSA:3.40.50.300 235 390 2.3E-16 T 23-10-2018 TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 SUPERFAMILY SSF52540 134 439 2.75E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_245 ffb5d18f2cb75f7a5345f87d3dd96ab7 602 Pfam PF01850 PIN domain 5 117 1.2E-7 T 23-10-2018 IPR002716 PIN domain TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 SUPERFAMILY SSF55481 12 146 5.75E-49 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Gene3D G3DSA:3.30.1330.30 285 426 1.4E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 SMART SM01194 12 146 1.2E-34 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Pfam PF03465 eRF1 domain 3 287 425 1.1E-34 T 23-10-2018 IPR005142 eRF1 domain 3 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 29 426 45.642 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Pfam PF03464 eRF1 domain 2 151 283 1.4E-49 T 23-10-2018 IPR005141 eRF1 domain 2 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Gene3D G3DSA:3.30.420.60 142 282 3.3E-54 T 23-10-2018 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Gene3D G3DSA:3.30.960.10 10 141 1.8E-54 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 SUPERFAMILY SSF55315 283 425 2.12E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 Pfam PF03463 eRF1 domain 1 28 144 5.0E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 SUPERFAMILY SSF53137 149 281 4.36E-44 T 23-10-2018 TAM4_692 0f8f5db0129e6746a4556e9b9cbe6e33 426 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 18 425 5.9E-183 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 Pfam PF01192 RNA polymerase Rpb6 5 51 4.3E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.042 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 Gene3D G3DSA:3.90.940.50 1 57 3.1E-27 T 23-10-2018 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 SUPERFAMILY SSF63562 3 55 3.53E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_50 9e09ee0e24015481f332ffa67af34ffa 57 PIRSF PIRSF000778 1 57 2.0E-22 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 Pfam PF00375 Sodium:dicarboxylate symporter family 13 416 7.8E-126 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 45 60 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 SUPERFAMILY SSF118215 13 418 6.93E-122 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 Gene3D G3DSA:1.10.3860.10 1 426 1.4E-176 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 232 251 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 364 384 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 337 356 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 9.6E-48 T 23-10-2018 TAM4_1796 0d5241eaebe07c803ed6cfb7010db1f6 426 PRINTS PR00173 Glutamate-aspartate symporter signature 302 328 9.6E-48 T 23-10-2018 TAM4_1360 2bd4bb3e84f08ddcc8ff00bd62b9bf29 171 SUPERFAMILY SSF47240 12 156 4.54E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1360 2bd4bb3e84f08ddcc8ff00bd62b9bf29 171 Gene3D G3DSA:1.20.1260.10 6 156 1.6E-33 T 23-10-2018 IPR012347 Ferritin-like TAM4_1360 2bd4bb3e84f08ddcc8ff00bd62b9bf29 171 Pfam PF02915 Rubrerythrin 16 152 1.0E-14 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_177 72beffcaad1333a1b1f35cf295fcbb59 215 Pfam PF02811 PHP domain 4 105 1.7E-7 T 23-10-2018 IPR004013 PHP domain GO:0003824 TAM4_177 72beffcaad1333a1b1f35cf295fcbb59 215 Gene3D G3DSA:3.20.20.140 1 214 5.3E-48 T 23-10-2018 TAM4_177 72beffcaad1333a1b1f35cf295fcbb59 215 SMART SM00481 3 75 1.5E-8 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TAM4_177 72beffcaad1333a1b1f35cf295fcbb59 215 SUPERFAMILY SSF89550 1 212 2.22E-40 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 Pfam PF01895 PhoU domain 18 100 8.1E-9 T 23-10-2018 IPR026022 PhoU domain TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 Gene3D G3DSA:3.30.70.1450 116 200 1.1E-22 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 Gene3D G3DSA:1.20.58.220 8 115 9.2E-21 T 23-10-2018 IPR038078 PhoU-like domain superfamily TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 Pfam PF02080 TrkA-C domain 124 190 4.6E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 SUPERFAMILY SSF109755 10 102 1.44E-14 T 23-10-2018 TAM4_792 d33bb38db65cba0f17ff5e5c85ff8906 201 SUPERFAMILY SSF116726 107 190 2.75E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 55 108 3.0E-21 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Gene3D G3DSA:3.10.20.400 3 96 5.6E-34 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Gene3D G3DSA:1.10.287.1080 121 209 2.1E-26 T 23-10-2018 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 121 204 19.089 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 SUPERFAMILY SSF101386 123 208 2.03E-21 T 23-10-2018 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 109 28.826 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 125 207 2.4E-16 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 7.1E-31 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 SUPERFAMILY SSF141734 6 114 1.14E-42 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 125 204 4.1E-28 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TAM4_1775 c4a68ead4ab4892a5f0c2f2b8929e30a 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 209 35.938 T 23-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 SUPERFAMILY SSF53383 10 383 1.17E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 Gene3D G3DSA:3.40.640.10 35 280 3.0E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 Gene3D G3DSA:3.90.1150.10 25 379 3.0E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 Pfam PF00266 Aminotransferase class-V 45 369 4.6E-40 T 23-10-2018 IPR000192 Aminotransferase class V domain TAM4_120 d1e4bd3b2aceee4809b5bdd4dbf936ef 385 PIRSF PIRSF000524 17 385 8.8E-102 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TAM4_1953 8bab0273d261285b968abe9551c282c3 113 SUPERFAMILY SSF81593 2 104 2.35E-37 T 23-10-2018 TAM4_1953 8bab0273d261285b968abe9551c282c3 113 Gene3D G3DSA:1.20.120.330 1 106 3.7E-32 T 23-10-2018 TAM4_1953 8bab0273d261285b968abe9551c282c3 113 Pfam PF05168 HEPN domain 2 104 6.4E-27 T 23-10-2018 IPR007842 HEPN domain TAM4_1953 8bab0273d261285b968abe9551c282c3 113 SMART SM00748 2 98 8.2E-27 T 23-10-2018 IPR007842 HEPN domain TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 SUPERFAMILY SSF50249 5 99 6.86E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 112 424 7.2E-87 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 Gene3D G3DSA:2.40.50.140 1 101 2.6E-30 T 23-10-2018 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 9.7E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 9.7E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 9.7E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 9.7E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 6.1E-16 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 Gene3D G3DSA:3.30.930.10 105 430 1.8E-117 T 23-10-2018 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 3.8E-130 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 430 37.687 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TAM4_753 9e03910c66eb21a7ceecdef8914dc37b 430 SUPERFAMILY SSF55681 110 425 2.38E-89 T 23-10-2018 TAM4_1027 55e4964e1ee33e09e51b6748a369c184 284 SUPERFAMILY SSF103481 39 132 6.67E-13 T 23-10-2018 TAM4_1027 55e4964e1ee33e09e51b6748a369c184 284 SUPERFAMILY SSF103481 177 271 5.75E-14 T 23-10-2018 TAM4_1027 55e4964e1ee33e09e51b6748a369c184 284 Pfam PF00892 EamA-like transporter family 139 268 1.7E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1027 55e4964e1ee33e09e51b6748a369c184 284 Pfam PF00892 EamA-like transporter family 8 131 5.5E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_53 b8384a77b20d0948ce5a60d5b899bbf4 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_53 b8384a77b20d0948ce5a60d5b899bbf4 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.52 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 TAM4_53 b8384a77b20d0948ce5a60d5b899bbf4 56 Gene3D G3DSA:4.10.830.10 1 56 4.3E-20 T 23-10-2018 TAM4_53 b8384a77b20d0948ce5a60d5b899bbf4 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 5.4E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SMART SM00487 33 259 2.8E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Pfam PF00270 DEAD/DEAH box helicase 38 222 3.4E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 PRINTS PR00379 Intein signature 550 562 1.6E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 PRINTS PR00379 Intein signature 933 942 1.6E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 PRINTS PR00379 Intein signature 678 693 1.6E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 PRINTS PR00379 Intein signature 406 419 1.6E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 PRINTS PR00379 Intein signature 646 658 1.6E-14 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SUPERFAMILY SSF52540 266 936 5.04E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:3.40.50.300 16 237 1.7E-53 T 23-10-2018 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:3.10.28.10 524 739 3.0E-35 T 23-10-2018 IPR027434 Homing endonuclease TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SUPERFAMILY SSF51294 348 873 4.32E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SMART SM00306 346 443 8.3E-16 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SMART SM00382 50 336 0.0075 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SMART SM00305 834 879 5.1E-5 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Pfam PF00271 Helicase conserved C-terminal domain 874 910 5.0E-5 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:3.40.50.300 255 345 5.7E-9 T 23-10-2018 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SUPERFAMILY SSF52540 21 231 1.19E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 SUPERFAMILY SSF55608 631 737 2.27E-17 T 23-10-2018 IPR027434 Homing endonuclease TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:2.170.16.10 346 464 2.4E-11 T 23-10-2018 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Pfam PF14890 Intein splicing domain 390 870 4.8E-19 T 23-10-2018 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:2.170.16.10 795 872 8.1E-6 T 23-10-2018 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Pfam PF14528 LAGLIDADG-like domain 646 735 4.1E-14 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Pfam PF14528 LAGLIDADG-like domain 551 608 5.4E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_972 26ffed1f1a486959c05068c9a2edf663 956 Gene3D G3DSA:3.40.50.300 873 937 1.0E-7 T 23-10-2018 TAM4_510 517c04277883e41578460cc978edd810 319 SUPERFAMILY SSF55326 9 134 1.06E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_510 517c04277883e41578460cc978edd810 319 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 2.2E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_510 517c04277883e41578460cc978edd810 319 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 309 1.4E-83 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TAM4_510 517c04277883e41578460cc978edd810 319 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 309 28.782 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TAM4_510 517c04277883e41578460cc978edd810 319 Pfam PF02769 AIR synthase related protein, C-terminal domain 144 293 2.9E-7 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_510 517c04277883e41578460cc978edd810 319 SUPERFAMILY SSF56042 137 296 4.93E-41 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_510 517c04277883e41578460cc978edd810 319 Gene3D G3DSA:3.90.650.10 139 309 5.2E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_510 517c04277883e41578460cc978edd810 319 PIRSF PIRSF005303 1 309 8.5E-91 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TAM4_510 517c04277883e41578460cc978edd810 319 Gene3D G3DSA:3.30.1330.10 1 138 4.1E-34 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_161 3acea78327164c39583790f031e58057 464 SUPERFAMILY SSF52980 341 458 5.01E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_161 3acea78327164c39583790f031e58057 464 Pfam PF03008 Archaea bacterial proteins of unknown function 309 408 5.6E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_161 3acea78327164c39583790f031e58057 464 Pfam PF09339 IclR helix-turn-helix domain 242 285 3.1E-6 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TAM4_161 3acea78327164c39583790f031e58057 464 SUPERFAMILY SSF46785 241 319 9.39E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_161 3acea78327164c39583790f031e58057 464 Gene3D G3DSA:1.10.10.10 239 300 1.6E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_161 3acea78327164c39583790f031e58057 464 Gene3D G3DSA:3.40.50.300 1 168 5.5E-33 T 23-10-2018 TAM4_161 3acea78327164c39583790f031e58057 464 Pfam PF01637 ATPase domain predominantly from Archaea 2 202 5.7E-33 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_161 3acea78327164c39583790f031e58057 464 SUPERFAMILY SSF52540 1 241 2.67E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_763 1e1f1f903034a02f3ac956e537fd2b50 118 Pfam PF03551 Transcriptional regulator PadR-like family 25 97 3.4E-21 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TAM4_763 1e1f1f903034a02f3ac956e537fd2b50 118 SUPERFAMILY SSF46785 14 110 3.04E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_763 1e1f1f903034a02f3ac956e537fd2b50 118 Gene3D G3DSA:1.10.10.10 9 117 1.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 Pfam PF00464 Serine hydroxymethyltransferase 8 388 5.8E-80 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 Gene3D G3DSA:3.40.640.10 36 278 2.9E-82 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 SUPERFAMILY SSF53383 4 421 4.3E-131 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 PIRSF PIRSF000412 1 423 3.2E-143 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 416 42.98 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TAM4_1931 c92ceeff3a2bb4152ba375d59c1b8e6b 427 Gene3D G3DSA:3.90.1150.10 279 425 3.0E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_898 52f3fb38f274d6477d5fbd6102da4e10 239 Pfam PF02633 Creatinine amidohydrolase 4 234 1.7E-60 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TAM4_898 52f3fb38f274d6477d5fbd6102da4e10 239 SUPERFAMILY SSF102215 2 235 1.22E-58 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TAM4_898 52f3fb38f274d6477d5fbd6102da4e10 239 Gene3D G3DSA:3.40.50.10310 1 237 5.2E-65 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TAM4_2056 8964df1132e81910b546700c0c04dffe 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 71 4.4E-14 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TAM4_2056 8964df1132e81910b546700c0c04dffe 85 SUPERFAMILY SSF143430 1 80 1.96E-26 T 23-10-2018 TAM4_2056 8964df1132e81910b546700c0c04dffe 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 16.187 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TAM4_2056 8964df1132e81910b546700c0c04dffe 85 Gene3D G3DSA:3.30.70.240 1 66 1.1E-31 T 23-10-2018 TAM4_2056 8964df1132e81910b546700c0c04dffe 85 Pfam PF09827 CRISPR associated protein Cas2 1 68 9.6E-24 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 6.3E-22 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 1.3E-22 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 27.909 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 Gene3D G3DSA:2.10.260.30 1 69 1.0E-27 T 23-10-2018 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 Gene3D G3DSA:1.10.10.250 73 164 5.4E-35 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 SUPERFAMILY SSF46906 66 138 3.01E-22 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 SMART SM00649 5 138 2.4E-63 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TAM4_561 2cbb84f4c809fc2208e6b00e14641897 165 SUPERFAMILY SSF54747 3 82 7.59E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 Gene3D G3DSA:1.10.8.60 206 283 3.2E-23 T 23-10-2018 TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 Gene3D G3DSA:3.40.50.300 1 205 2.0E-41 T 23-10-2018 TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 SUPERFAMILY SSF46785 281 355 1.5E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 SUPERFAMILY SSF52540 1 280 4.98E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 Pfam PF01637 ATPase domain predominantly from Archaea 14 247 4.3E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1226 700577b3e6abb86aac636bd33fc11b03 358 Gene3D G3DSA:1.10.10.10 284 356 3.9E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 188 3.3E-67 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 SUPERFAMILY SSF51735 1 192 1.05E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 2.3E-145 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 412 1.4E-26 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 PIRSF PIRSF500134 1 424 1.3E-147 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 Gene3D G3DSA:3.40.50.720 1 216 6.4E-80 T 23-10-2018 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 Gene3D G3DSA:3.40.50.720 217 427 2.7E-79 T 23-10-2018 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 PIRSF PIRSF000124 1 427 3.9E-142 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 294 8.8E-39 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 SUPERFAMILY SSF48179 202 296 1.87E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 SMART SM00984 317 415 7.6E-41 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TAM4_218 d19ebeaa8f96deb2ad70d88c946bf051 427 SUPERFAMILY SSF52413 303 418 1.22E-31 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 Gene3D G3DSA:1.10.287.10 83 151 1.3E-32 T 23-10-2018 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 SMART SM01386 1 60 9.3E-35 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 SUPERFAMILY SSF47060 66 142 2.94E-25 T 23-10-2018 IPR009068 S15/NS1, RNA-binding TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 Pfam PF00312 Ribosomal protein S15 73 148 1.3E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 131 2.0E-4 T 23-10-2018 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.739 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 Gene3D G3DSA:1.10.8.1030 36 82 4.0E-21 T 23-10-2018 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 SMART SM01387 70 149 1.1E-27 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 1.9E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_556 b1930a5fcc76491bc3d698efdc4a4530 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_959 81510383262fde85b0f89275db7eca0a 655 Gene3D G3DSA:1.10.510.10 286 571 1.1E-59 T 23-10-2018 TAM4_959 81510383262fde85b0f89275db7eca0a 655 SUPERFAMILY SSF56112 301 554 1.29E-60 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_959 81510383262fde85b0f89275db7eca0a 655 SMART SM00220 309 561 6.6E-52 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_959 81510383262fde85b0f89275db7eca0a 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 418 430 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_959 81510383262fde85b0f89275db7eca0a 655 Pfam PF00069 Protein kinase domain 309 550 1.5E-43 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_959 81510383262fde85b0f89275db7eca0a 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 315 337 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_2383 23d619acaef9a3a77c1f0def5fa77941 221 SMART SM00382 32 217 1.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2383 23d619acaef9a3a77c1f0def5fa77941 221 SUPERFAMILY SSF52540 4 220 7.29E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2383 23d619acaef9a3a77c1f0def5fa77941 221 Gene3D G3DSA:3.40.50.300 2 221 4.0E-59 T 23-10-2018 TAM4_2383 23d619acaef9a3a77c1f0def5fa77941 221 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_2383 23d619acaef9a3a77c1f0def5fa77941 221 Pfam PF00005 ABC transporter 23 170 7.9E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 PIRSF PIRSF003025 1 136 2.7E-43 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 SUPERFAMILY SSF50249 71 130 9.85E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 4.0E-5 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 SUPERFAMILY SSF50104 5 78 9.53E-21 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 133 4.7E-47 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 33.893 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 4.1E-10 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 SMART SM01376 70 134 4.5E-14 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 Gene3D G3DSA:2.40.50.140 71 135 8.8E-28 T 23-10-2018 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 TAM4_780 3eaac1ba3c93e274d996cd6a347c26be 136 Gene3D G3DSA:2.30.30.30 1 70 4.2E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 Gene3D G3DSA:3.40.50.261 136 288 3.9E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 SUPERFAMILY SSF52210 130 286 2.35E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 Gene3D G3DSA:3.40.50.720 1 127 2.7E-31 T 23-10-2018 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 SUPERFAMILY SSF52210 292 439 2.35E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 SUPERFAMILY SSF51735 2 133 1.58E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 Gene3D G3DSA:3.40.50.261 289 445 8.2E-54 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 285 1.7E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 Pfam PF13380 CoA binding domain 10 131 8.0E-17 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1163 d5ee1816ce17c3b02a0e0a08a14ab861 445 SMART SM00881 6 100 2.2E-19 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1621 1ccf56e5577624cfb6586f1a8fce7c0f 246 Gene3D G3DSA:3.30.70.1890 1 121 9.4E-40 T 23-10-2018 TAM4_1621 1ccf56e5577624cfb6586f1a8fce7c0f 246 Pfam PF01881 CRISPR associated protein Cas6 94 238 4.9E-33 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_1621 1ccf56e5577624cfb6586f1a8fce7c0f 246 PIRSF PIRSF005054 1 242 2.7E-61 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_1621 1ccf56e5577624cfb6586f1a8fce7c0f 246 Gene3D G3DSA:3.30.70.1900 122 242 2.1E-37 T 23-10-2018 TAM4_1621 1ccf56e5577624cfb6586f1a8fce7c0f 246 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 51 237 6.0E-46 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_1403 2d76c9a63169f5e973eb3d6e8b2b862c 156 Pfam PF00717 Peptidase S24-like 39 87 4.4E-6 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TAM4_1403 2d76c9a63169f5e973eb3d6e8b2b862c 156 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 4 150 2.0E-39 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_1403 2d76c9a63169f5e973eb3d6e8b2b862c 156 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 101 112 3.0E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_1403 2d76c9a63169f5e973eb3d6e8b2b862c 156 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 3.0E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_1403 2d76c9a63169f5e973eb3d6e8b2b862c 156 SUPERFAMILY SSF51306 37 123 2.04E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TAM4_828 ba6c98beb31c55857076ac7b3d5138ba 177 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 171 1.4E-22 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 TAM4_828 ba6c98beb31c55857076ac7b3d5138ba 177 Gene3D G3DSA:1.10.260.40 79 177 1.4E-11 T 23-10-2018 TAM4_828 ba6c98beb31c55857076ac7b3d5138ba 177 SUPERFAMILY SSF47413 80 146 9.65E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_828 ba6c98beb31c55857076ac7b3d5138ba 177 SMART SM00530 90 145 2.8E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_828 ba6c98beb31c55857076ac7b3d5138ba 177 Pfam PF01381 Helix-turn-helix 93 142 5.9E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_725 2b0b1970f727472281979a7ee7e0cddb 366 Gene3D G3DSA:3.40.50.150 172 360 4.6E-26 T 23-10-2018 TAM4_725 2b0b1970f727472281979a7ee7e0cddb 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 8.1E-12 T 23-10-2018 IPR000241 Putative RNA methylase domain TAM4_725 2b0b1970f727472281979a7ee7e0cddb 366 SUPERFAMILY SSF53335 173 339 2.29E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 Gene3D G3DSA:3.30.70.260 126 204 1.6E-89 T 23-10-2018 TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 220 1.3E-66 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 SUPERFAMILY SSF75445 130 206 1.11E-24 T 23-10-2018 TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 SUPERFAMILY SSF100950 2 148 1.4E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 224 37.061 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 Gene3D G3DSA:3.40.50.1360 5 220 1.6E-89 T 23-10-2018 TAM4_133 e66a5863e3d3ceef42caf21faa40002b 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 222 5.8E-84 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF02867 Ribonucleotide reductase, barrel domain 756 1225 8.4E-222 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF09061 Stirrup 637 715 1.7E-45 T 23-10-2018 IPR015146 Ribonucleotide reductase, stirrup GO:0016788 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 3.1E-28 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 756 1234 1.2E-198 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.20.70.20 750 1240 2.5E-178 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR00379 Intein signature 542 554 1.2E-11 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR00379 Intein signature 391 404 1.2E-11 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR00379 Intein signature 569 584 1.2E-11 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR00379 Intein signature 729 746 1.2E-11 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR00379 Intein signature 440 452 1.2E-11 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR01183 Ribonucleotide reductase large chain signature 1013 1036 9.2E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR01183 Ribonucleotide reductase large chain signature 947 970 9.2E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR01183 Ribonucleotide reductase large chain signature 800 819 9.2E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR01183 Ribonucleotide reductase large chain signature 1078 1105 9.2E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 PRINTS PR01183 Ribonucleotide reductase large chain signature 985 1007 9.2E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF55608 528 632 7.94E-23 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.10.28.10 441 525 2.3E-53 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF54786 637 715 8.63E-39 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:2.170.16.10 303 440 9.8E-52 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF51998 755 1236 3.36E-140 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.20.70.20 170 302 2.9E-20 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.20.70.20 67 169 4.7E-6 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 302 404 1.3E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF14528 LAGLIDADG-like domain 542 615 3.9E-14 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF51294 302 756 2.55E-41 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.30.160.90 640 715 1.2E-47 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF51998 234 302 7.63E-6 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 732 756 4.0E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF14890 Intein splicing domain 309 755 5.9E-43 T 23-10-2018 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF55608 430 527 3.91E-43 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF09062 PI-PfuI Endonuclease subdomain 430 527 8.1E-52 T 23-10-2018 IPR015147 PI-PfuI intein endonuclease, subdomain KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Gene3D G3DSA:3.10.28.10 526 639 3.0E-38 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 Pfam PF03477 ATP cone domain 5 93 2.9E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SUPERFAMILY SSF48168 9 154 7.85E-12 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SMART SM00306 300 429 1.3E-21 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1100 da910d18b4d5d26314f61abde022aedc 1361 SMART SM00305 715 761 2.4E-8 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 Gene3D G3DSA:1.20.58.100 370 461 8.4E-18 T 23-10-2018 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 1 447 2.6E-156 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 Gene3D G3DSA:3.90.700.10 212 302 9.5E-109 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 310 332 4.4E-6 T 23-10-2018 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.4E-6 T 23-10-2018 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 Pfam PF02910 Fumarate reductase flavoprotein C-term 423 448 8.3E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 SUPERFAMILY SSF46977 386 450 9.94E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 SUPERFAMILY SSF56425 204 308 4.93E-33 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 Pfam PF00890 FAD binding domain 5 347 3.1E-68 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 SUPERFAMILY SSF51905 5 363 2.82E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_544 2d09e52c866f1ac28e0a035bca33ad26 465 Gene3D G3DSA:3.50.50.60 5 354 9.5E-109 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_2010 9316c954391dc2b330a609ca55f59f72 399 Gene3D G3DSA:3.40.640.10 29 287 5.5E-145 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_2010 9316c954391dc2b330a609ca55f59f72 399 PIRSF PIRSF005572 15 399 6.4E-49 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TAM4_2010 9316c954391dc2b330a609ca55f59f72 399 SUPERFAMILY SSF53383 5 395 1.39E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_2010 9316c954391dc2b330a609ca55f59f72 399 Pfam PF00266 Aminotransferase class-V 18 386 2.5E-137 T 23-10-2018 IPR000192 Aminotransferase class V domain TAM4_2010 9316c954391dc2b330a609ca55f59f72 399 Gene3D G3DSA:3.90.1150.10 7 388 5.5E-145 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 Pfam PF01381 Helix-turn-helix 12 59 1.3E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 SMART SM00530 11 65 9.3E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 SMART SM00116 140 186 0.29 T 23-10-2018 IPR000644 CBS domain TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 SMART SM00116 76 123 1.9E-8 T 23-10-2018 IPR000644 CBS domain TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 SUPERFAMILY SSF54631 68 183 7.71E-27 T 23-10-2018 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 SUPERFAMILY SSF47413 10 59 4.02E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 Gene3D G3DSA:3.10.580.10 66 184 8.1E-27 T 23-10-2018 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 Pfam PF00571 CBS domain 69 122 1.1E-12 T 23-10-2018 IPR000644 CBS domain TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 Pfam PF00571 CBS domain 135 183 4.5E-6 T 23-10-2018 IPR000644 CBS domain TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 Gene3D G3DSA:1.10.260.40 9 62 2.8E-16 T 23-10-2018 TAM4_637 1968b88a43ffaa5bc3a0ba17927d378a 191 PIRSF PIRSF037253 1 189 4.3E-78 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 44.858 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 237 1.8E-99 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 SUPERFAMILY SSF53167 1 255 8.12E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 Gene3D G3DSA:3.40.50.1580 1 257 6.4E-102 T 23-10-2018 TAM4_1279 8f0db5a59775b3337fa993ce46fec3d3 257 Pfam PF01048 Phosphorylase superfamily 3 235 2.6E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 5 275 42.59 T 23-10-2018 IPR033686 Tyrosine recombinase XerA TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 Gene3D G3DSA:1.10.443.10 92 283 1.8E-77 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 78 1.7E-5 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 Pfam PF00589 Phage integrase family 100 263 6.3E-49 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 Gene3D G3DSA:1.10.150.130 3 91 1.2E-20 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal TAM4_1517 c3025a3e8a667a6e29283abd9774ba8c 283 SUPERFAMILY SSF56349 8 271 3.24E-61 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TAM4_1072 c5ae8f0d1a70918f56a79d62d13e04b2 284 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 29 258 1.5E-32 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 SUPERFAMILY SSF53774 2 325 1.44E-98 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 Gene3D G3DSA:3.40.50.1170 1 195 5.5E-69 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 PIRSF PIRSF001220 1 324 2.4E-93 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 77 87 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 SMART SM00870 2 313 5.9E-122 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 PIRSF PIRSF500176 1 322 1.2E-98 T 23-10-2018 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 325 1.7E-92 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 6.9E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 PRINTS PR00139 Asparaginase/glutaminase family signature 250 268 6.9E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 PRINTS PR00139 Asparaginase/glutaminase family signature 76 94 6.9E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 Gene3D G3DSA:3.40.50.40 200 327 2.9E-41 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TAM4_1473 86938bf096c8e19bfd2e091be47bfa8e 328 Pfam PF00710 Asparaginase, N-terminal 2 186 3.8E-60 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TAM4_1914 590fe9acfe61ea78068fadabee7ad8b3 143 Gene3D G3DSA:3.30.460.10 3 111 1.8E-13 T 23-10-2018 TAM4_1914 590fe9acfe61ea78068fadabee7ad8b3 143 Pfam PF01909 Nucleotidyltransferase domain 28 68 2.7E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1914 590fe9acfe61ea78068fadabee7ad8b3 143 SUPERFAMILY SSF81301 12 123 4.91E-17 T 23-10-2018 TAM4_1192 4ae924e5d56e04e639dca830c6631cd7 528 Gene3D G3DSA:1.20.1640.10 333 525 2.4E-12 T 23-10-2018 TAM4_1192 4ae924e5d56e04e639dca830c6631cd7 528 Pfam PF02355 Protein export membrane protein 351 513 2.2E-16 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TAM4_1192 4ae924e5d56e04e639dca830c6631cd7 528 Gene3D G3DSA:3.30.70.3400 38 127 1.1E-8 T 23-10-2018 TAM4_1192 4ae924e5d56e04e639dca830c6631cd7 528 SUPERFAMILY SSF82866 334 513 8.89E-27 T 23-10-2018 TAM4_1192 4ae924e5d56e04e639dca830c6631cd7 528 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 9 527 19.061 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 SUPERFAMILY SSF54791 148 226 8.67E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 SMART SM00316 63 137 4.0E-8 T 23-10-2018 IPR022967 RNA-binding domain, S1 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 SUPERFAMILY SSF110324 3 58 7.06E-14 T 23-10-2018 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Gene3D G3DSA:2.40.50.100 1 57 2.8E-21 T 23-10-2018 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 SMART SM00322 146 211 1.7E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Pfam PF15985 KH domain 149 195 3.1E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 SUPERFAMILY SSF50249 59 152 4.42E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Gene3D G3DSA:2.40.50.140 58 142 1.2E-20 T 23-10-2018 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Gene3D G3DSA:3.30.1370.10 149 234 1.1E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 3.1E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_309 45930b24ce8eb8506d294dbb45a4ac3d 254 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 40.187 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 Pfam PF00326 Prolyl oligopeptidase family 424 634 6.8E-58 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 SUPERFAMILY SSF53474 378 634 8.63E-70 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 Gene3D G3DSA:2.120.10.30 26 145 1.8E-15 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 Gene3D G3DSA:2.120.10.30 152 293 1.1E-7 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 Pfam PF07676 WD40-like Beta Propeller Repeat 56 87 1.1E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 SUPERFAMILY SSF82171 27 368 5.36E-31 T 23-10-2018 TAM4_635 374d2db23167dc14a8d1b773ac173b90 635 Gene3D G3DSA:3.40.50.1820 380 635 2.3E-72 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 5.4E-28 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 770 3.2E-293 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 SUPERFAMILY SSF52009 352 461 2.35E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 SUPERFAMILY SSF51621 484 777 2.51E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 351 1.3E-121 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 SUPERFAMILY SSF56059 4 381 1.88E-108 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 472 769 7.2E-98 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 511 530 6.7E-14 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 692 707 6.7E-14 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 675 690 6.7E-14 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 728 740 6.7E-14 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Gene3D G3DSA:3.30.470.20 198 354 7.6E-55 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Gene3D G3DSA:3.50.30.10 355 461 1.3E-42 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Gene3D G3DSA:3.20.20.60 462 787 1.0E-104 T 23-10-2018 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 PIRSF PIRSF000854 1 774 7.6E-210 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 Gene3D G3DSA:3.30.1490.20 3 197 5.5E-75 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_928 167d2cbdc7a07c28a8192738a582f2ef 790 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 675 693 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 295 1.4E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TAM4_1433 9094f025a218df695a551c4f5b496c87 467 Gene3D G3DSA:3.40.50.261 300 464 4.1E-47 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 SUPERFAMILY SSF52210 134 296 1.57E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 SMART SM00881 7 105 5.5E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 SUPERFAMILY SSF51735 4 133 5.69E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1433 9094f025a218df695a551c4f5b496c87 467 Pfam PF13380 CoA binding domain 11 137 1.7E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 Gene3D G3DSA:3.40.50.720 1 132 3.2E-43 T 23-10-2018 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 Gene3D G3DSA:3.40.50.261 134 298 1.9E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1433 9094f025a218df695a551c4f5b496c87 467 SUPERFAMILY SSF52210 302 461 2.22E-37 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_651 c2abc95739ce691c53a3a662f1ebc9a2 120 Gene3D G3DSA:3.30.70.3250 1 120 6.0E-50 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TAM4_651 c2abc95739ce691c53a3a662f1ebc9a2 120 PIRSF PIRSF004952 4 120 4.7E-47 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 TAM4_651 c2abc95739ce691c53a3a662f1ebc9a2 120 Pfam PF01900 Rpp14/Pop5 family 17 113 5.5E-22 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TAM4_651 c2abc95739ce691c53a3a662f1ebc9a2 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.963 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TAM4_651 c2abc95739ce691c53a3a662f1ebc9a2 120 SUPERFAMILY SSF160350 4 116 3.27E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TAM4_1456 8d043c55f65d5a9cf0bbcfd797f4c2ba 98 Pfam PF13601 Winged helix DNA-binding domain 18 93 2.3E-17 T 23-10-2018 IPR027395 Winged helix DNA-binding domain TAM4_1456 8d043c55f65d5a9cf0bbcfd797f4c2ba 98 Gene3D G3DSA:1.10.10.10 3 96 1.4E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1456 8d043c55f65d5a9cf0bbcfd797f4c2ba 98 SUPERFAMILY SSF46785 11 94 2.28E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1456 8d043c55f65d5a9cf0bbcfd797f4c2ba 98 SMART SM00418 6 93 2.6E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 105 124 4.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 157 169 4.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 125 139 4.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 141 156 4.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 Pfam PF13180 PDZ domain 207 274 5.1E-16 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 Pfam PF02163 Peptidase family M50 117 366 1.7E-19 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 SMART SM00228 189 265 2.3E-8 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 Gene3D G3DSA:2.30.42.10 205 293 1.3E-22 T 23-10-2018 TAM4_1219 9c59f68ae0fb9dc3b6bc70215a7b0f44 379 SUPERFAMILY SSF50156 206 296 1.97E-22 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 TAM4_490 72425eca42255be01c300debd8150fb4 215 Pfam PF01863 Protein of unknown function DUF45 11 197 5.7E-49 T 23-10-2018 IPR002725 Protein of unknown function DUF45 TAM4_490 72425eca42255be01c300debd8150fb4 215 Gene3D G3DSA:3.30.2010.10 107 198 8.0E-20 T 23-10-2018 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SMART SM00962 100 295 4.0E-103 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.422 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Gene3D G3DSA:1.10.260.30 310 443 1.1E-50 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SUPERFAMILY SSF47364 1 94 9.94E-24 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SMART SM00963 2 87 5.1E-25 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SMART SM00382 99 273 4.6E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SUPERFAMILY SSF47446 297 429 4.71E-44 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 SUPERFAMILY SSF52540 94 297 6.39E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Gene3D G3DSA:3.40.50.300 91 284 4.0E-123 T 23-10-2018 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 3.7E-21 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Gene3D G3DSA:1.20.120.140 6 305 4.0E-123 T 23-10-2018 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 2.4E-77 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 Pfam PF02978 Signal peptide binding domain 327 425 5.4E-34 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_193 9957ace71f8e05f6d4c0f018ea946eec 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 SUPERFAMILY SSF46548 95 198 2.88E-23 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Gene3D G3DSA:3.30.70.20 610 692 3.7E-13 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Gene3D G3DSA:3.50.50.60 315 514 3.9E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Gene3D G3DSA:3.50.50.60 185 313 1.6E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 72 4.2E-10 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 SUPERFAMILY SSF51971 186 428 3.65E-75 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 SUPERFAMILY SSF54292 1 96 2.1E-22 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 SUPERFAMILY SSF53706 701 938 1.45E-10 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 SUPERFAMILY SSF54862 579 693 2.72E-21 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Gene3D G3DSA:3.10.20.740 1 114 1.1E-24 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 188 480 1.7E-43 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 97 175 1.2E-17 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 30 47 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 PRINTS PR00419 Adrenodoxin reductase family signature 353 366 3.7E-23 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 PRINTS PR00419 Adrenodoxin reductase family signature 320 334 3.7E-23 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 PRINTS PR00419 Adrenodoxin reductase family signature 189 211 3.7E-23 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 PRINTS PR00419 Adrenodoxin reductase family signature 254 264 3.7E-23 T 23-10-2018 TAM4_108 40002826e27efb1749e3d24dbaf7469d 949 PRINTS PR00419 Adrenodoxin reductase family signature 212 225 3.7E-23 T 23-10-2018 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 Gene3D G3DSA:3.40.50.20 1 121 8.6E-42 T 23-10-2018 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 1.7E-41 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 Gene3D G3DSA:3.30.470.20 122 379 8.9E-94 T 23-10-2018 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 PIRSF PIRSF004602 1 380 3.4E-142 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 Gene3D G3DSA:3.30.1490.20 152 218 8.9E-94 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 SUPERFAMILY SSF56059 139 380 2.53E-76 T 23-10-2018 TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 SUPERFAMILY SSF52440 1 133 1.06E-40 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TAM4_813 0e069968c2d2050a6d5d6f1dcbcc07c0 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 2.7E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_2108 5402ef8f9b72aea8ad7a9cf5dd4d4006 239 SUPERFAMILY SSF56281 7 228 2.03E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2108 5402ef8f9b72aea8ad7a9cf5dd4d4006 239 SMART SM00849 31 220 7.3E-39 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2108 5402ef8f9b72aea8ad7a9cf5dd4d4006 239 Gene3D G3DSA:3.60.15.10 6 235 2.4E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2108 5402ef8f9b72aea8ad7a9cf5dd4d4006 239 Pfam PF00753 Metallo-beta-lactamase superfamily 31 220 7.9E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1965 933ea7fc9bc10d1dde675f2cccef9f99 375 SUPERFAMILY SSF111331 86 145 2.62E-8 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TAM4_1965 933ea7fc9bc10d1dde675f2cccef9f99 375 PIRSF PIRSF016907 1 375 7.8E-149 T 23-10-2018 IPR011386 Putative ATP-NAD kinase TAM4_1965 933ea7fc9bc10d1dde675f2cccef9f99 375 Pfam PF01513 ATP-NAD kinase 2 374 4.3E-47 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TAM4_1965 933ea7fc9bc10d1dde675f2cccef9f99 375 Gene3D G3DSA:3.40.50.10330 83 204 1.3E-6 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TAM4_76 452c02e88a3c248beb93b4157d420398 154 Gene3D G3DSA:3.40.50.1010 5 150 6.4E-11 T 23-10-2018 TAM4_76 452c02e88a3c248beb93b4157d420398 154 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 141 9.751 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_76 452c02e88a3c248beb93b4157d420398 154 SMART SM00670 4 132 3.5E-17 T 23-10-2018 IPR002716 PIN domain TAM4_76 452c02e88a3c248beb93b4157d420398 154 SUPERFAMILY SSF88723 7 142 2.19E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_76 452c02e88a3c248beb93b4157d420398 154 Pfam PF01850 PIN domain 7 131 7.5E-22 T 23-10-2018 IPR002716 PIN domain TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 SUPERFAMILY SSF88697 95 166 7.18E-17 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 174 388 4.1E-64 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 SMART SM00359 96 170 5.0E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 338 5.7E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 209 219 5.7E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 275 287 5.7E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 180 194 5.7E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 388 5.7E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 SUPERFAMILY SSF53335 11 389 2.68E-57 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Gene3D G3DSA:3.40.50.150 195 389 3.1E-62 T 23-10-2018 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 14 84 2.9E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Gene3D G3DSA:3.30.70.3130 5 92 2.2E-12 T 23-10-2018 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Pfam PF01189 16S rRNA methyltransferase RsmB/F 198 387 1.9E-55 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Pfam PF01472 PUA domain 100 166 3.1E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 96 165 3.9E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_1346 1cddbfbac9b71a31fe5302554b2a4878 389 Gene3D G3DSA:2.30.130.10 93 168 8.2E-16 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 Pfam PF01170 Putative RNA methylase family UPF0020 156 294 1.4E-26 T 23-10-2018 IPR000241 Putative RNA methylase domain TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 Gene3D G3DSA:3.30.2130.30 15 142 2.9E-6 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 Gene3D G3DSA:3.40.50.150 153 333 2.9E-35 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 294 6.1E-8 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 6.1E-8 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 6.1E-8 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 SMART SM00981 56 141 1.8E-7 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 328 8.1E-98 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 SUPERFAMILY SSF143437 31 132 2.62E-9 T 23-10-2018 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 Pfam PF02926 THUMP domain 19 133 1.3E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1865 a2e0f14c195c139a1f065c182beb9394 333 SUPERFAMILY SSF53335 145 291 9.87E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 SMART SM01193 7 135 8.2E-97 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 Hamap MF_00318 Enolase [eno]. 5 414 46.255 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 Gene3D G3DSA:3.30.390.10 2 128 6.7E-57 T 23-10-2018 IPR029017 Enolase-like, N-terminal TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 Gene3D G3DSA:3.20.20.120 129 429 1.8E-135 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 SUPERFAMILY SSF51604 139 429 8.65E-127 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PIRSF PIRSF001400 3 428 1.2E-198 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 162 175 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 108 124 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 39 53 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 366 383 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 337 351 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 PRINTS PR00148 Enolase signature 314 325 5.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 8.5E-132 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 Pfam PF03952 Enolase, N-terminal domain 7 135 4.1E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.2E-198 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 SMART SM01192 140 428 2.2E-206 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1197 04faf8f32aa114b78876dee6cc09a28e 430 SUPERFAMILY SSF54826 6 140 2.15E-57 T 23-10-2018 TAM4_30 20152bfced195f57c1ed95731ef7d15a 183 SUPERFAMILY SSF52402 43 182 6.59E-7 T 23-10-2018 TAM4_30 20152bfced195f57c1ed95731ef7d15a 183 Gene3D G3DSA:3.40.50.620 38 183 4.0E-7 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1869 be471e84e24a2e0fcfcd08ba797428ec 170 Gene3D G3DSA:3.40.920.10 1 170 2.3E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_1869 be471e84e24a2e0fcfcd08ba797428ec 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 5.0E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TAM4_1869 be471e84e24a2e0fcfcd08ba797428ec 170 SUPERFAMILY SSF53323 2 168 1.96E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 257 5.1E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 PIRSF PIRSF006816 1 263 7.1E-60 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 SUPERFAMILY SSF63380 2 93 1.87E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 SUPERFAMILY SSF52343 89 256 3.02E-14 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 Gene3D G3DSA:3.40.50.80 100 211 1.3E-23 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_463 55280d84de3e3cdff21087cc33d6c541 292 Gene3D G3DSA:2.40.30.10 1 92 5.3E-15 T 23-10-2018 TAM4_489 48b05db1d0bef9f7b3756f4303abe568 394 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 142 394 1.0E-72 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_489 48b05db1d0bef9f7b3756f4303abe568 394 Gene3D G3DSA:1.10.645.20 30 394 1.5E-114 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_489 48b05db1d0bef9f7b3756f4303abe568 394 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 64 75 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_489 48b05db1d0bef9f7b3756f4303abe568 394 SUPERFAMILY SSF56762 41 394 1.31E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 3.0E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 3.0E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 3.0E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 3.0E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.056 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 Pfam PF01199 Ribosomal protein L34e 3 83 1.2E-23 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_132 d0ee46b8f26f653765c34e3d681e4412 90 Gene3D G3DSA:3.40.1800.40 29 86 2.4E-9 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 560 570 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 SUPERFAMILY SSF52743 70 780 1.44E-68 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 Pfam PF00082 Subtilase family 167 613 2.1E-59 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 366 376 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 Gene3D G3DSA:3.40.50.200 312 632 1.1E-72 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 Gene3D G3DSA:3.40.50.200 154 236 7.4E-6 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 PRINTS PR00723 Subtilisin serine protease family (S8) signature 559 575 2.4E-17 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 PRINTS PR00723 Subtilisin serine protease family (S8) signature 362 375 2.4E-17 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_759 6eb720e11ebf91a7573b26fb5f9257d5 1311 PRINTS PR00723 Subtilisin serine protease family (S8) signature 167 186 2.4E-17 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 6.8E-50 T 23-10-2018 TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 1.5E-97 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 SMART SM01211 1 221 7.5E-133 T 23-10-2018 TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 45.352 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 PIRSF PIRSF001586 1 223 1.5E-84 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 SUPERFAMILY SSF52317 3 221 1.53E-77 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_978 7ae7a11e3846251bef1fb59f70864ad3 223 Gene3D G3DSA:3.40.50.880 2 223 9.6E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 SUPERFAMILY SSF48150 17 220 5.02E-63 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 Gene3D G3DSA:1.10.340.30 32 145 3.7E-65 T 23-10-2018 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 SMART SM00478 49 199 7.5E-59 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 PIRSF PIRSF001435 11 223 3.5E-43 T 23-10-2018 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 Pfam PF00633 Helix-hairpin-helix motif 112 141 3.0E-7 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 183 6.5E-19 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 ProSitePatterns PS01155 Endonuclease III family signature. 115 144 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 Gene3D G3DSA:1.10.1670.10 29 217 3.7E-65 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 Hamap MF_00942 Endonuclease III [nth]. 13 223 33.675 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TAM4_2085 8fb84ea02d4f6fb29f9b4d7ad5cf4ca2 239 SMART SM00525 200 220 3.3E-6 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TAM4_1650 24a2290ed98ca1864dc3ab45f89aaf06 160 Pfam PF00011 Hsp20/alpha crystallin family 56 151 1.5E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TAM4_1650 24a2290ed98ca1864dc3ab45f89aaf06 160 Gene3D G3DSA:2.60.40.790 2 159 1.2E-33 T 23-10-2018 IPR008978 HSP20-like chaperone TAM4_1650 24a2290ed98ca1864dc3ab45f89aaf06 160 SUPERFAMILY SSF49764 24 151 4.45E-34 T 23-10-2018 IPR008978 HSP20-like chaperone TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Gene3D G3DSA:3.40.1190.20 209 477 1.2E-74 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 475 7.9E-71 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.255 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 SUPERFAMILY SSF64153 4 226 2.75E-50 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 SUPERFAMILY SSF53613 212 475 2.41E-60 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 PIRSF PIRSF017184 1 479 3.5E-98 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Gene3D G3DSA:3.40.50.10260 8 204 3.8E-43 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.736 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Pfam PF01256 Carbohydrate kinase 227 472 8.1E-50 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 7.7E-35 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 10 183 3.6E-43 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TAM4_1449 b7758ea4b214975b4d92be2ffaa61289 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 Gene3D G3DSA:3.40.640.10 43 251 2.5E-103 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 Gene3D G3DSA:3.90.1150.10 17 328 2.5E-103 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 331 2.1E-96 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 332 54.399 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 201 210 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 SUPERFAMILY SSF53383 14 329 1.14E-81 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1525 4745e20b8e953d2706a09608b1259c0a 338 Pfam PF00155 Aminotransferase class I and II 21 325 3.9E-51 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 466 7.4E-74 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 Gene3D G3DSA:3.90.76.10 41 195 1.4E-149 T 23-10-2018 TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 Gene3D G3DSA:3.10.105.10 285 517 1.4E-149 T 23-10-2018 TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 597 616 1.0E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 SUPERFAMILY SSF53850 28 546 7.85E-106 T 23-10-2018 TAM4_784 9514a703c74a39b08a7dfa42bb201a37 617 Gene3D G3DSA:3.40.190.10 30 541 1.4E-149 T 23-10-2018 TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 Gene3D G3DSA:2.40.30.10 2 91 4.6E-12 T 23-10-2018 TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 SUPERFAMILY SSF63380 3 91 1.07E-13 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 PIRSF PIRSF006816 1 256 7.2E-44 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 SUPERFAMILY SSF52343 110 249 2.47E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 Gene3D G3DSA:3.40.50.80 99 204 4.8E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_2460 d0fc402aa1c37037c42c029032640dd3 283 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 5.0E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 SUPERFAMILY SSF103486 35 361 5.89E-72 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 Gene3D G3DSA:1.20.1690.10 111 208 5.8E-54 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 23.878 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 361 1.3E-97 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 Gene3D G3DSA:1.20.1690.10 219 322 5.8E-54 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 Gene3D G3DSA:1.10.132.50 35 352 5.8E-54 T 23-10-2018 TAM4_1347 c7db4697c08433bc8adaa44b45bcafe5 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 359 3.0E-62 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1377 64cc34cde4612493dc8cbd9451200088 425 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 121 380 1.5E-57 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1377 64cc34cde4612493dc8cbd9451200088 425 Pfam PF00374 Nickel-dependent hydrogenase 46 114 1.1E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TAM4_1377 64cc34cde4612493dc8cbd9451200088 425 SUPERFAMILY SSF56762 17 380 2.22E-105 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1377 64cc34cde4612493dc8cbd9451200088 425 Gene3D G3DSA:1.10.645.20 8 380 1.6E-122 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_2088 231e5935a072479d730451380d45864c 400 Pfam PF04055 Radical SAM superfamily 21 180 1.7E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_2088 231e5935a072479d730451380d45864c 400 Gene3D G3DSA:3.20.20.70 10 341 1.2E-44 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_2088 231e5935a072479d730451380d45864c 400 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 293 360 4.5E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_2088 231e5935a072479d730451380d45864c 400 Pfam PF13353 4Fe-4S single cluster domain 20 92 8.0E-6 T 23-10-2018 TAM4_2088 231e5935a072479d730451380d45864c 400 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 10 375 1.9E-157 T 23-10-2018 IPR027634 Radical SAM protein, BA_1875 family TAM4_2088 231e5935a072479d730451380d45864c 400 SMART SM00729 16 220 5.1E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_2088 231e5935a072479d730451380d45864c 400 SUPERFAMILY SSF102114 11 352 4.58E-66 T 23-10-2018 TAM4_2088 231e5935a072479d730451380d45864c 400 PIRSF PIRSF037420 7 382 3.2E-93 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TAM4_2088 231e5935a072479d730451380d45864c 400 Pfam PF13186 Iron-sulfur cluster-binding domain 290 345 5.8E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_1366 2bd8c950c062d3d3b901dd74d33e2d75 275 Pfam PF00294 pfkB family carbohydrate kinase 5 272 8.9E-37 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TAM4_1366 2bd8c950c062d3d3b901dd74d33e2d75 275 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 230 243 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TAM4_1366 2bd8c950c062d3d3b901dd74d33e2d75 275 SUPERFAMILY SSF53613 3 272 1.56E-57 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1366 2bd8c950c062d3d3b901dd74d33e2d75 275 Gene3D G3DSA:3.40.1190.20 2 274 2.9E-63 T 23-10-2018 IPR029056 Ribokinase-like TAM4_825 da8a9060ed4d173453304576d56e1d80 440 Gene3D G3DSA:2.30.39.10 234 438 3.1E-131 T 23-10-2018 TAM4_825 da8a9060ed4d173453304576d56e1d80 440 Gene3D G3DSA:3.30.497.10 77 382 3.1E-131 T 23-10-2018 TAM4_825 da8a9060ed4d173453304576d56e1d80 440 ProSitePatterns PS00284 Serpins signature. 411 421 - T 23-10-2018 IPR023795 Serpin, conserved site TAM4_825 da8a9060ed4d173453304576d56e1d80 440 SMART SM00093 79 438 3.9E-134 T 23-10-2018 IPR023796 Serpin domain TAM4_825 da8a9060ed4d173453304576d56e1d80 440 Pfam PF00079 Serpin (serine protease inhibitor) 76 438 2.6E-120 T 23-10-2018 IPR023796 Serpin domain TAM4_825 da8a9060ed4d173453304576d56e1d80 440 SUPERFAMILY SSF56574 69 438 2.09E-129 T 23-10-2018 IPR036186 Serpin superfamily TAM4_306 d4764beb1f4b0da3868494921700dcfe 200 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TAM4_306 d4764beb1f4b0da3868494921700dcfe 200 Gene3D G3DSA:3.40.50.150 2 199 4.7E-32 T 23-10-2018 TAM4_306 d4764beb1f4b0da3868494921700dcfe 200 Pfam PF08241 Methyltransferase domain 41 135 3.0E-23 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TAM4_306 d4764beb1f4b0da3868494921700dcfe 200 SUPERFAMILY SSF53335 4 199 1.46E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1915 0f7e6a5a7de507a50657ea3d3ba2ac34 224 Gene3D G3DSA:1.10.10.580 147 216 1.4E-32 T 23-10-2018 IPR023093 ScpA-like, C-terminal TAM4_1915 0f7e6a5a7de507a50657ea3d3ba2ac34 224 Pfam PF02616 Segregation and condensation protein ScpA 18 164 5.6E-13 T 23-10-2018 IPR003768 Segregation and condensation protein A TAM4_1227 9715a3d1c1b809c2115771f4a05c1e86 193 SUPERFAMILY SSF81301 32 168 2.94E-8 T 23-10-2018 TAM4_1227 9715a3d1c1b809c2115771f4a05c1e86 193 Gene3D G3DSA:3.30.460.40 9 166 7.5E-7 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 2.7E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Gene3D G3DSA:3.30.70.240 466 718 5.0E-75 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Gene3D G3DSA:3.40.50.300 7 222 1.7E-73 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Pfam PF00679 Elongation factor G C-terminus 621 707 6.9E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SUPERFAMILY SSF54211 463 623 1.95E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SUPERFAMILY SSF54980 388 463 1.15E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.6E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SUPERFAMILY SSF54980 624 718 3.56E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Pfam PF03764 Elongation factor G, domain IV 513 618 7.8E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Gene3D G3DSA:3.30.230.10 472 720 5.0E-75 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Gene3D G3DSA:3.30.70.870 388 465 8.6E-28 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.8 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Pfam PF14492 Elongation Factor G, domain II 387 459 1.3E-26 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SUPERFAMILY SSF52540 10 261 3.74E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SMART SM00838 621 708 3.5E-44 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SUPERFAMILY SSF50447 259 373 2.55E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Gene3D G3DSA:2.40.30.10 259 386 5.3E-28 T 23-10-2018 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 SMART SM00889 505 619 3.6E-22 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TAM4_1859 33ac5f1dd9de81ba9e1c8b3b98f0a21f 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 1.6E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_1519 c1105efaa7d199d9897580770b4f2054 340 Pfam PF11536 Protein of unknown function (DUF3226) 103 339 3.4E-79 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TAM4_1519 c1105efaa7d199d9897580770b4f2054 340 Gene3D G3DSA:3.40.50.10620 102 327 7.6E-64 T 23-10-2018 TAM4_1519 c1105efaa7d199d9897580770b4f2054 340 ProDom PD038575 MJECL12 PLASMID PH0156 103 325 2.0E-81 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TAM4_1519 c1105efaa7d199d9897580770b4f2054 340 SUPERFAMILY SSF160945 101 337 1.05E-87 T 23-10-2018 TAM4_1519 c1105efaa7d199d9897580770b4f2054 340 Gene3D G3DSA:1.10.3490.10 238 326 7.6E-64 T 23-10-2018 TAM4_184 9f633af08efdf356e97daf378b9aa386 51 Gene3D G3DSA:2.20.28.70 1 48 2.6E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TAM4_184 9f633af08efdf356e97daf378b9aa386 51 SMART SM01377 1 46 4.7E-9 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TAM4_184 9f633af08efdf356e97daf378b9aa386 51 SUPERFAMILY SSF57829 2 46 5.68E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_184 9f633af08efdf356e97daf378b9aa386 51 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.206 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 ProSitePatterns PS01134 FtsZ protein signature 1. 75 109 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 PRINTS PR00423 Cell division protein FtsZ signature 129 149 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 PRINTS PR00423 Cell division protein FtsZ signature 242 263 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 PRINTS PR00423 Cell division protein FtsZ signature 157 178 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 PRINTS PR00423 Cell division protein FtsZ signature 219 241 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 Gene3D G3DSA:3.40.50.1440 37 250 1.8E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 Gene3D G3DSA:3.30.1330.20 255 365 3.2E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 356 9.3E-137 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 SMART SM00865 237 353 2.0E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 40 371 38.298 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 44 204 2.0E-47 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 SUPERFAMILY SSF55307 237 349 3.43E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 ProSitePatterns PS01135 FtsZ protein signature 2. 128 149 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 Pfam PF12327 FtsZ family, C-terminal domain 252 344 1.9E-31 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 SMART SM00864 44 235 4.9E-108 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_536 ed6acf4b48a482b1ecec7466b2066659 373 SUPERFAMILY SSF52490 38 236 1.57E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_771 86b198ed89f8511f287284eb2800c669 340 SUPERFAMILY SSF159071 255 339 2.48E-18 T 23-10-2018 TAM4_771 86b198ed89f8511f287284eb2800c669 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.0E-24 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TAM4_771 86b198ed89f8511f287284eb2800c669 340 Gene3D G3DSA:1.10.10.10 3 101 1.8E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_771 86b198ed89f8511f287284eb2800c669 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 2.2E-55 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TAM4_771 86b198ed89f8511f287284eb2800c669 340 SUPERFAMILY SSF46785 4 96 2.1E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2044 4e602367679d5b9b2d88fd1fa8c761f5 171 Gene3D G3DSA:2.20.28.10 133 171 6.1E-18 T 23-10-2018 TAM4_2044 4e602367679d5b9b2d88fd1fa8c761f5 171 Gene3D G3DSA:1.20.1260.10 3 132 3.9E-46 T 23-10-2018 IPR012347 Ferritin-like TAM4_2044 4e602367679d5b9b2d88fd1fa8c761f5 171 SUPERFAMILY SSF57802 137 170 3.81E-10 T 23-10-2018 TAM4_2044 4e602367679d5b9b2d88fd1fa8c761f5 171 Pfam PF02915 Rubrerythrin 10 124 2.2E-25 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2044 4e602367679d5b9b2d88fd1fa8c761f5 171 SUPERFAMILY SSF47240 7 131 1.09E-35 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_667 6aec9c03c4106dbd553f3d18bab6cc8c 235 Pfam PF09968 Uncharacterized protein domain (DUF2202) 75 234 5.2E-64 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TAM4_667 6aec9c03c4106dbd553f3d18bab6cc8c 235 Gene3D G3DSA:1.20.1260.10 70 235 7.2E-69 T 23-10-2018 IPR012347 Ferritin-like TAM4_667 6aec9c03c4106dbd553f3d18bab6cc8c 235 SUPERFAMILY SSF47240 74 214 3.68E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 PIRSF PIRSF005653 1 65 3.8E-31 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 2.0E-16 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 SUPERFAMILY SSF46924 1 63 1.06E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 Gene3D G3DSA:1.10.10.60 1 65 2.2E-33 T 23-10-2018 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 4.6E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_231 01f55bb2a04602d3bf8a947b8b21b31a 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.036 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 Pfam PF00265 Thymidine kinase 6 189 5.4E-53 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 PIRSF PIRSF035805 3 194 6.4E-66 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 Gene3D G3DSA:3.30.60.20 144 194 1.3E-24 T 23-10-2018 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 Gene3D G3DSA:3.40.50.300 1 142 1.5E-47 T 23-10-2018 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 SUPERFAMILY SSF57716 144 192 6.18E-16 T 23-10-2018 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 SUPERFAMILY SSF52540 5 143 3.47E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 176 189 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TAM4_772 1357e073bd1b2e46f53a1b37584f6f67 194 Hamap MF_00124 Thymidine kinase [tdk]. 4 192 36.16 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TAM4_1733 d668c75a1b2879f80e60826b1859162f 275 Gene3D G3DSA:3.40.50.10470 96 275 2.1E-63 T 23-10-2018 TAM4_1733 d668c75a1b2879f80e60826b1859162f 275 Gene3D G3DSA:1.20.120.420 1 95 1.4E-35 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1733 d668c75a1b2879f80e60826b1859162f 275 Pfam PF01008 Initiation factor 2 subunit family 19 271 1.9E-52 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TAM4_1733 d668c75a1b2879f80e60826b1859162f 275 SUPERFAMILY SSF100950 4 272 1.97E-70 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TAM4_2143 5c794147cb54fdbcb8f90c73cf4f3c6c 262 Gene3D G3DSA:3.30.1600.10 30 169 2.5E-91 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TAM4_2143 5c794147cb54fdbcb8f90c73cf4f3c6c 262 Pfam PF02146 Sir2 family 21 199 1.9E-58 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 TAM4_2143 5c794147cb54fdbcb8f90c73cf4f3c6c 262 Gene3D G3DSA:3.40.50.1220 12 242 2.5E-91 T 23-10-2018 TAM4_2143 5c794147cb54fdbcb8f90c73cf4f3c6c 262 SUPERFAMILY SSF52467 4 247 2.17E-89 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TAM4_2143 5c794147cb54fdbcb8f90c73cf4f3c6c 262 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 14 249 62.064 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 121 1.0E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 SMART SM00382 171 310 3.6E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 175 308 3.1E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 20 379 5.0E-199 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 3 396 47.495 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 ProSitePatterns PS00674 AAA-protein family signature. 278 296 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Gene3D G3DSA:1.10.8.60 309 380 1.9E-28 T 23-10-2018 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Gene3D G3DSA:3.40.50.300 128 308 7.9E-71 T 23-10-2018 TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 SUPERFAMILY SSF52540 133 382 5.86E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1578 9d0b91e8f1ca7967c4bf632cda2f8653 397 Gene3D G3DSA:2.40.50.140 24 127 9.1E-28 T 23-10-2018 TAM4_785 e6494768f8e7513dc486cc1bde80f704 391 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 378 3.5E-155 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 TAM4_785 e6494768f8e7513dc486cc1bde80f704 391 Gene3D G3DSA:3.90.550.10 1 391 1.4E-156 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_785 e6494768f8e7513dc486cc1bde80f704 391 SUPERFAMILY SSF53448 53 178 6.66E-6 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_785 e6494768f8e7513dc486cc1bde80f704 391 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 379 1.5E-178 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 9.0E-9 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1117 5.7E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 3.6E-40 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:2.40.50.150 683 874 1.9E-145 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:3.90.1100.10 21 178 4.0E-13 T 23-10-2018 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:3.90.1110.10 179 335 6.7E-60 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:3.90.1100.10 336 511 8.3E-56 T 23-10-2018 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04563 RNA polymerase beta subunit 28 381 9.8E-55 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 SUPERFAMILY SSF64484 12 1120 0.0 T 23-10-2018 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:2.40.270.10 653 1011 1.9E-145 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 5.1E-133 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 4.3E-20 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 4.1E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1722 15da56d44fd21375a9e921b7ab7b696b 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 6.8E-41 T 23-10-2018 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 SUPERFAMILY SSF51621 4 340 1.57E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 Gene3D G3DSA:2.40.33.10 74 170 1.3E-170 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 SUPERFAMILY SSF52935 324 473 7.72E-34 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 Pfam PF00224 Pyruvate kinase, barrel domain 6 337 1.9E-120 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 Gene3D G3DSA:3.40.1380.20 337 469 1.3E-170 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 Gene3D G3DSA:3.20.20.60 7 336 1.3E-170 T 23-10-2018 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 470 1.2E-24 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 SUPERFAMILY SSF50800 75 169 2.27E-25 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 473 6.6E-170 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 314 330 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 270 294 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 188 202 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 245 269 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 295 313 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 63 79 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_1686 9ba35bdc19306d74622e5a806f4d5741 474 PRINTS PR01050 Pyruvate kinase family signature 218 244 4.5E-62 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TAM4_943 5c20bb16df70808634421d495f8a0abe 323 Gene3D G3DSA:3.40.50.300 1 322 3.5E-87 T 23-10-2018 TAM4_943 5c20bb16df70808634421d495f8a0abe 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 297 5.3E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_943 5c20bb16df70808634421d495f8a0abe 323 SUPERFAMILY SSF52540 3 262 1.14E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_943 5c20bb16df70808634421d495f8a0abe 323 SMART SM00382 32 229 2.4E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_943 5c20bb16df70808634421d495f8a0abe 323 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_943 5c20bb16df70808634421d495f8a0abe 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 1.7E-26 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_943 5c20bb16df70808634421d495f8a0abe 323 Pfam PF00005 ABC transporter 24 179 4.1E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 SUPERFAMILY SSF51182 191 464 1.36E-65 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 Gene3D G3DSA:2.60.120.10 351 451 1.2E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 SUPERFAMILY SSF53448 2 271 9.97E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 Gene3D G3DSA:3.90.550.10 1 345 2.7E-114 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 463 2.8E-160 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 Pfam PF01050 Mannose-6-phosphate isomerase 310 460 1.2E-65 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TAM4_856 bf2d64ab967e59bb9e351fe46140b8d4 465 Pfam PF00483 Nucleotidyl transferase 2 277 2.6E-58 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 Gene3D G3DSA:3.40.50.360 259 406 9.1E-29 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 SMART SM00849 39 209 7.9E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 PIRSF PIRSF005243 3 409 8.1E-112 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 2.4E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 SUPERFAMILY SSF56281 10 255 5.37E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 Gene3D G3DSA:3.60.15.10 1 258 5.1E-86 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2128 77665f551954d5163f6d33b67903b5bd 409 SUPERFAMILY SSF52218 262 406 1.43E-27 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_1916 e6b5d7b927cd251a7a6d6dc8277e0ae9 93 SUPERFAMILY SSF143011 1 90 3.66E-17 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_1916 e6b5d7b927cd251a7a6d6dc8277e0ae9 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 14 92 5.8E-9 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TAM4_1916 e6b5d7b927cd251a7a6d6dc8277e0ae9 93 Gene3D G3DSA:3.30.2310.20 1 93 2.7E-24 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.6E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 Gene3D G3DSA:1.20.120.640 306 473 8.8E-39 T 23-10-2018 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 SMART SM00840 356 417 4.6E-17 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 SUPERFAMILY SSF52374 4 314 4.35E-114 T 23-10-2018 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 SUPERFAMILY SSF47323 316 473 1.14E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 473 6.9E-184 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 Pfam PF09190 DALR domain 356 415 7.4E-18 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 3.6E-139 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 40.045 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TAM4_1487 ce1ad5ec219c8c37789b688c2392b7bd 476 Gene3D G3DSA:3.40.50.620 1 305 4.6E-151 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 2.6E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 Gene3D G3DSA:3.20.20.70 10 372 9.0E-129 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 PIRSF PIRSF003314 7 363 1.7E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 SMART SM01240 30 349 0.001 T 23-10-2018 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 SUPERFAMILY SSF51395 32 366 2.51E-80 T 23-10-2018 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.368 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TAM4_226 1f423a3ae2ecb7bc7a444e51b65da0ef 372 Pfam PF01070 FMN-dependent dehydrogenase 14 346 2.0E-23 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 Gene3D G3DSA:3.40.50.300 416 636 3.1E-38 T 23-10-2018 TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 Gene3D G3DSA:3.40.630.30 220 349 1.3E-7 T 23-10-2018 TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 SUPERFAMILY SSF52540 424 625 3.55E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 Pfam PF00005 ABC transporter 437 573 1.2E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 SMART SM00382 446 625 6.2E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2033 399b1692c16bdb5cd485431b40e97f60 636 SUPERFAMILY SSF55729 231 371 5.97E-8 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Gene3D G3DSA:3.40.50.300 327 589 3.5E-67 T 23-10-2018 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Gene3D G3DSA:3.40.50.300 1 326 7.5E-103 T 23-10-2018 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Pfam PF00037 4Fe-4S binding domain 44 67 4.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 75 95 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 48 72 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 150 176 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 20 35 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 103 128 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 PRINTS PR01868 ABC transporter family E signature 134 150 3.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 SUPERFAMILY SSF52540 96 285 5.74E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Pfam PF00005 ABC transporter 361 482 2.2E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 SMART SM00382 98 288 2.7E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 SMART SM00382 363 532 6.8E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 9.1E-12 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 SUPERFAMILY SSF52540 358 529 6.46E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 SUPERFAMILY SSF54862 4 124 4.44E-24 T 23-10-2018 TAM4_1873 5b2f8a9ca898b873cdb601c2616b15e5 589 Pfam PF00005 ABC transporter 96 238 2.8E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 Gene3D G3DSA:3.30.70.940 2 87 2.4E-34 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 SMART SM00738 3 87 3.5E-21 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 SMART SM00739 92 119 2.6E-7 T 23-10-2018 IPR005824 KOW TAM4_645 9329deaf1c57305baa42774974f9d69a 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.909 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 3.4E-54 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 SUPERFAMILY SSF50104 55 148 4.14E-18 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_645 9329deaf1c57305baa42774974f9d69a 152 Gene3D G3DSA:2.30.30.30 88 152 8.3E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_645 9329deaf1c57305baa42774974f9d69a 152 Pfam PF00467 KOW motif 95 126 2.5E-9 T 23-10-2018 IPR005824 KOW TAM4_645 9329deaf1c57305baa42774974f9d69a 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 2.8E-24 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Gene3D G3DSA:3.30.70.20 586 642 2.5E-11 T 23-10-2018 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 1.2E-14 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 SUPERFAMILY SSF52518 380 603 2.94E-32 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 SUPERFAMILY SSF54862 585 644 2.33E-13 T 23-10-2018 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 PIRSF PIRSF006439 5 647 2.2E-260 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 6.2E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 9.7E-272 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Gene3D G3DSA:3.40.50.970 7 196 8.3E-52 T 23-10-2018 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 SUPERFAMILY SSF52922 249 355 5.06E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 SUPERFAMILY SSF52518 14 245 3.09E-55 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Gene3D G3DSA:3.40.50.970 387 572 2.4E-24 T 23-10-2018 TAM4_624 dbec10f5d73120bcecf345da6acccad1 648 Pfam PF12838 4Fe-4S dicluster domain 593 639 3.1E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 Hamap MF_00620 Putative transcriptional regulatory protein . 3 135 29.958 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 Pfam PF04545 Sigma-70, region 4 7 49 1.9E-6 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 Gene3D G3DSA:3.30.1190.10 17 135 4.5E-37 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 137 2.5E-59 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 PIRSF PIRSF004932 3 146 4.8E-66 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 Pfam PF14601 DNA_binding protein, TFX, C-term 52 132 8.8E-24 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal TAM4_2415 38a81d787fd64a5d02a4b88500f03241 146 SUPERFAMILY SSF89915 17 121 2.48E-25 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 SUPERFAMILY SSF51419 31 295 8.58E-53 T 23-10-2018 IPR029066 PLP-binding barrel TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 Gene3D G3DSA:3.20.20.10 39 288 1.2E-107 T 23-10-2018 IPR029066 PLP-binding barrel TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 65 83 - T 23-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 294 383 3.3E-22 T 23-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 15 404 1.7E-102 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 393 412 7.6E-9 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 83 100 7.6E-9 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 311 329 7.6E-9 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 171 180 7.6E-9 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 293 6.1E-42 T 23-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 Gene3D G3DSA:2.40.37.10 19 405 1.2E-107 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 234 250 - T 23-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 85 97 1.7E-21 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 196 209 1.7E-21 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 283 302 1.7E-21 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 383 396 1.7E-21 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 83 1.7E-21 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TAM4_1880 f5676d5e44dcba382dc1f557a941e01f 412 SUPERFAMILY SSF50621 269 404 7.33E-44 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TAM4_471 cad3ea1d4e39b9fb1ea19d123c230934 142 Gene3D G3DSA:2.40.50.140 70 142 9.3E-22 T 23-10-2018 TAM4_471 cad3ea1d4e39b9fb1ea19d123c230934 142 SUPERFAMILY SSF141322 75 140 3.4E-20 T 23-10-2018 TAM4_471 cad3ea1d4e39b9fb1ea19d123c230934 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 140 8.3E-18 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TAM4_2333 9bc4a125659b8dab233d6ca377a8d0f1 187 SUPERFAMILY SSF46785 6 53 3.79E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2333 9bc4a125659b8dab233d6ca377a8d0f1 187 Gene3D G3DSA:1.10.10.10 5 87 2.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Gene3D G3DSA:1.10.150.20 733 807 2.1E-23 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SUPERFAMILY SSF52540 67 494 5.57E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Pfam PF12826 Helix-hairpin-helix motif 750 800 3.5E-10 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SMART SM00278 778 797 0.015 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SMART SM00278 746 765 1000.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Pfam PF02732 ERCC4 domain 598 716 6.8E-29 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SMART SM00891 595 675 4.1E-31 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SUPERFAMILY SSF52980 594 723 9.38E-38 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Gene3D G3DSA:3.40.50.300 16 214 1.4E-74 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Gene3D G3DSA:3.40.50.300 224 492 2.0E-100 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Pfam PF00271 Helicase conserved C-terminal domain 357 474 7.0E-24 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SMART SM00490 386 475 2.3E-25 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Pfam PF00270 DEAD/DEAH box helicase 29 183 1.9E-19 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SUPERFAMILY SSF47781 733 802 6.3E-16 T 23-10-2018 IPR010994 RuvA domain 2-like TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Gene3D G3DSA:3.40.50.10130 591 732 3.0E-53 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 Gene3D G3DSA:1.20.1320.20 227 352 2.0E-100 T 23-10-2018 TAM4_2130 4715d7ca5bceda028968b62cc8061d99 807 SMART SM00487 21 216 2.7E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 SUPERFAMILY SSF55347 141 302 1.96E-52 T 23-10-2018 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 334 1.3E-183 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 123 1.4E-14 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 SUPERFAMILY SSF51735 4 159 2.6E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 147 297 3.7E-31 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 PIRSF PIRSF000149 2 319 2.5E-87 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 Gene3D G3DSA:3.30.360.10 141 302 1.0E-149 T 23-10-2018 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 335 192.018 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 SMART SM00846 4 142 6.3E-23 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 140 147 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1537 4f7c78e0108d8aef7480eae1e438eaa1 335 Gene3D G3DSA:3.40.50.720 4 332 1.0E-149 T 23-10-2018 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 Gene3D G3DSA:3.90.930.12 7 85 5.7E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 1.3E-79 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 SUPERFAMILY SSF56053 8 85 2.06E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 Gene3D G3DSA:3.90.930.12 86 182 1.6E-38 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 PIRSF PIRSF002162 5 182 5.6E-43 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 Pfam PF00347 Ribosomal protein L6 13 85 8.5E-20 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 Pfam PF00347 Ribosomal protein L6 97 171 3.3E-17 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 SUPERFAMILY SSF56053 86 177 1.96E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_113 c23121242c802c94c828f4376bc3e04f 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.68 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Gene3D G3DSA:3.90.1860.10 559 960 6.8E-179 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Gene3D G3DSA:3.90.1860.10 1 104 1.5E-40 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Pfam PF01139 tRNA-splicing ligase RtcB 45 960 2.0E-179 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 556 578 1.5E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Gene3D G3DSA:3.10.28.10 242 439 4.4E-22 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 97 176 1.4E-11 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SMART SM00305 535 583 3.1E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Pfam PF14528 LAGLIDADG-like domain 357 443 1.4E-16 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Pfam PF14890 Intein splicing domain 109 577 1.8E-14 T 23-10-2018 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 PRINTS PR00379 Intein signature 244 256 3.0E-12 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 PRINTS PR00379 Intein signature 398 413 3.0E-12 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 PRINTS PR00379 Intein signature 163 176 3.0E-12 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 PRINTS PR00379 Intein signature 358 370 3.0E-12 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 PRINTS PR00379 Intein signature 572 581 3.0E-12 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SUPERFAMILY SSF103365 577 960 5.89E-147 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SUPERFAMILY SSF51294 96 577 6.87E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SMART SM00306 95 196 1.2E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 Gene3D G3DSA:2.170.16.10 105 231 3.5E-8 T 23-10-2018 TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SUPERFAMILY SSF55608 342 450 2.0E-17 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1534 8db9b4df73a14173ebbe0a2c08921b2e 960 SUPERFAMILY SSF103365 2 97 2.22E-30 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TAM4_272 781842fc51933d255eb402247fd7dc5c 138 ProSitePatterns PS00360 Ribosomal protein S9 signature. 71 89 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TAM4_272 781842fc51933d255eb402247fd7dc5c 138 Pfam PF00380 Ribosomal protein S9/S16 11 138 1.4E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TAM4_272 781842fc51933d255eb402247fd7dc5c 138 Gene3D G3DSA:3.30.230.10 1 138 3.9E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_272 781842fc51933d255eb402247fd7dc5c 138 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 6 138 4.0E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_272 781842fc51933d255eb402247fd7dc5c 138 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 6 138 37.259 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_272 781842fc51933d255eb402247fd7dc5c 138 SUPERFAMILY SSF54211 6 138 6.45E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_484 04700df55a571efd16ac1e126733e74f 640 PRINTS PR01038 Arginyl-tRNA synthetase signature 138 154 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 PRINTS PR01038 Arginyl-tRNA synthetase signature 328 349 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 PRINTS PR01038 Arginyl-tRNA synthetase signature 162 175 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 PRINTS PR01038 Arginyl-tRNA synthetase signature 123 138 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 SUPERFAMILY SSF47323 514 640 7.19E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_484 04700df55a571efd16ac1e126733e74f 640 SUPERFAMILY SSF52374 118 511 1.69E-76 T 23-10-2018 TAM4_484 04700df55a571efd16ac1e126733e74f 640 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 364 1.3E-80 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 SMART SM00836 518 640 2.9E-53 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 92 3.0E-15 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Gene3D G3DSA:1.10.730.10 522 640 1.8E-42 T 23-10-2018 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Gene3D G3DSA:3.30.1360.70 7 119 7.8E-31 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 SUPERFAMILY SSF55190 8 114 3.01E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Pfam PF00750 tRNA synthetases class I (R) 105 365 4.6E-26 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Pfam PF00750 tRNA synthetases class I (R) 388 490 1.9E-10 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Gene3D G3DSA:3.40.50.620 120 521 5.0E-157 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_484 04700df55a571efd16ac1e126733e74f 640 Pfam PF05746 DALR anticodon binding domain 518 640 9.0E-38 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TAM4_484 04700df55a571efd16ac1e126733e74f 640 SMART SM01016 8 93 1.4E-21 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_484 04700df55a571efd16ac1e126733e74f 640 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 640 28.081 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TAM4_484 04700df55a571efd16ac1e126733e74f 640 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 133 142 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 Pfam PF09378 HAS barrel domain 8 65 1.4E-7 T 23-10-2018 IPR018538 Helicase HerA, barrel domain TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 Gene3D G3DSA:3.40.50.300 305 533 2.2E-57 T 23-10-2018 TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 Gene3D G3DSA:3.40.50.300 127 276 4.8E-23 T 23-10-2018 TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 Pfam PF05872 Bacterial protein of unknown function (DUF853) 401 502 2.9E-5 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 SUPERFAMILY SSF52540 137 519 1.78E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1809 fc24ffa04a51e0c9b5ab5e1462a3bf06 555 Pfam PF01935 Domain of unknown function DUF87 141 370 1.0E-42 T 23-10-2018 IPR002789 Helicase HerA, central domain TAM4_782 002ee0f953555007c0904368cf7e1bb6 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 8.5E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TAM4_782 002ee0f953555007c0904368cf7e1bb6 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 112 8.3E-22 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TAM4_782 002ee0f953555007c0904368cf7e1bb6 134 SUPERFAMILY SSF50249 7 116 1.42E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_782 002ee0f953555007c0904368cf7e1bb6 134 Gene3D G3DSA:1.10.12.20 3 50 5.1E-6 T 23-10-2018 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 625 2.9E-219 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Gene3D G3DSA:3.40.50.970 411 563 6.5E-23 T 23-10-2018 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 PIRSF PIRSF006439 12 632 1.7E-218 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Gene3D G3DSA:3.40.50.970 7 198 4.2E-55 T 23-10-2018 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 553 1.1E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 610 621 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 215 5.7E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 SUPERFAMILY SSF54862 562 628 3.49E-13 T 23-10-2018 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Pfam PF00037 4Fe-4S binding domain 604 626 1.3E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 Gene3D G3DSA:3.30.70.20 564 635 4.5E-11 T 23-10-2018 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 SUPERFAMILY SSF52518 20 253 1.52E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 SUPERFAMILY SSF52922 244 334 2.47E-6 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_2144 ad749712a023b6653053a4fdaeeac92e 635 SUPERFAMILY SSF52518 375 560 3.63E-36 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_1247 3059764c380cb74022b288fcba1fec57 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 4.2E-8 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 SUPERFAMILY SSF63380 5 85 5.02E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_1247 3059764c380cb74022b288fcba1fec57 233 SUPERFAMILY SSF52343 80 228 1.44E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_1247 3059764c380cb74022b288fcba1fec57 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 1.1E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TAM4_1247 3059764c380cb74022b288fcba1fec57 233 Gene3D G3DSA:2.40.30.10 3 83 7.7E-11 T 23-10-2018 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.519 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit TAM4_1247 3059764c380cb74022b288fcba1fec57 233 PIRSF PIRSF006816 1 232 1.9E-76 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 5.1E-6 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 5.1E-6 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 5.1E-6 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TAM4_1247 3059764c380cb74022b288fcba1fec57 233 Gene3D G3DSA:3.40.50.80 86 196 7.6E-28 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_2136 9d9398cd1ca2ab326e1cc36e83d3010e 73 Gene3D G3DSA:2.30.30.90 10 73 1.1E-21 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain TAM4_2136 9d9398cd1ca2ab326e1cc36e83d3010e 73 SUPERFAMILY SSF50037 3 72 1.97E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TAM4_2136 9d9398cd1ca2ab326e1cc36e83d3010e 73 Pfam PF04023 FeoA domain 1 71 5.9E-19 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TAM4_2136 9d9398cd1ca2ab326e1cc36e83d3010e 73 SMART SM00899 1 72 4.2E-19 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 3.1E-149 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Gene3D G3DSA:3.30.70.3360 314 362 6.4E-39 T 23-10-2018 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Pfam PF09414 RNA ligase 86 240 3.5E-18 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Gene3D G3DSA:3.30.70.3350 244 374 6.4E-39 T 23-10-2018 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 1.3E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Gene3D G3DSA:3.30.470.30 96 197 2.1E-68 T 23-10-2018 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Gene3D G3DSA:2.20.25.320 7 67 6.1E-23 T 23-10-2018 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 Gene3D G3DSA:3.30.1490.70 70 241 2.1E-68 T 23-10-2018 TAM4_12 21f045b5cdc116d0b7f28d51558b3ee2 380 SUPERFAMILY SSF56091 64 260 2.26E-38 T 23-10-2018 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 2.4E-153 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 Gene3D G3DSA:3.30.420.40 4 298 1.7E-114 T 23-10-2018 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 SUPERFAMILY SSF53067 1 293 1.08E-37 T 23-10-2018 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 Gene3D G3DSA:3.30.420.40 122 278 1.7E-114 T 23-10-2018 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 4.8E-102 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.394 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 Pfam PF00814 Glycoprotease family 22 292 1.6E-96 T 23-10-2018 IPR000905 Gcp-like domain TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_1151 a5b189e1d3fc51df53364c650a35810b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 5.6E-42 T 23-10-2018 IPR017861 Kae1/TsaD family TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 PIRSF PIRSF001259 1 386 2.0E-131 T 23-10-2018 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 4 185 2.0E-44 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 197 382 4.3E-68 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 Gene3D G3DSA:3.90.870.10 1 193 6.0E-46 T 23-10-2018 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 SUPERFAMILY SSF142695 193 360 2.09E-59 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 SUPERFAMILY SSF55821 2 185 1.83E-47 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 192 384 37.709 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 Pfam PF00925 GTP cyclohydrolase II 199 358 5.1E-68 T 23-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TAM4_2081 5dfbe8bda492bcfca7e0329d9552dc2a 386 Gene3D G3DSA:3.40.50.10990 194 358 1.0E-68 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TAM4_1138 359d24fc3b8d0159a054cac268542a0e 250 Gene3D G3DSA:3.40.1390.30 6 238 5.4E-77 T 23-10-2018 TAM4_1138 359d24fc3b8d0159a054cac268542a0e 250 SUPERFAMILY SSF102705 1 245 3.66E-71 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TAM4_1138 359d24fc3b8d0159a054cac268542a0e 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 5.2E-59 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TAM4_1138 359d24fc3b8d0159a054cac268542a0e 250 Gene3D G3DSA:3.40.1390.30 96 221 5.4E-77 T 23-10-2018 TAM4_1138 359d24fc3b8d0159a054cac268542a0e 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 238 4.2E-59 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TAM4_616 3b10f720346e6f015ab2d432fd90e9a3 447 Pfam PF00534 Glycosyl transferases group 1 251 417 3.3E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TAM4_616 3b10f720346e6f015ab2d432fd90e9a3 447 Gene3D G3DSA:3.40.50.2000 217 425 5.3E-107 T 23-10-2018 TAM4_616 3b10f720346e6f015ab2d432fd90e9a3 447 Pfam PF08323 Starch synthase catalytic domain 2 201 1.4E-34 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TAM4_616 3b10f720346e6f015ab2d432fd90e9a3 447 SUPERFAMILY SSF53756 1 438 1.4E-84 T 23-10-2018 TAM4_616 3b10f720346e6f015ab2d432fd90e9a3 447 Gene3D G3DSA:3.40.50.2000 2 435 5.3E-107 T 23-10-2018 TAM4_1051 32d5ea71ce2e7c4b5af98ef9df3ec4c2 134 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 14 121 1.9E-18 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF55608 272 359 2.72E-14 T 23-10-2018 IPR027434 Homing endonuclease TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SMART SM00530 435 483 2.3E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 60 144 3.6E-16 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF01381 Helix-turn-helix 440 482 4.1E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 PRINTS PR00379 Intein signature 574 591 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 PRINTS PR00379 Intein signature 180 192 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 PRINTS PR00379 Intein signature 131 144 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 PRINTS PR00379 Intein signature 274 286 2.8E-15 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF14890 Intein splicing domain 70 599 2.1E-27 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:2.170.16.10 526 598 1.5E-13 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF52540 12 59 8.33E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF52540 600 757 2.38E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF48019 775 864 2.07E-23 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SMART SM00306 58 169 9.4E-27 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:1.10.8.60 710 773 4.0E-27 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 577 600 3.4E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:1.20.272.10 774 867 1.2E-36 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 62 4.0E-5 T 23-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:3.40.50.300 1 63 1.8E-17 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:3.40.50.300 599 709 9.4E-36 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SMART SM00305 557 605 3.8E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF08542 Replication factor C C-terminal domain 775 860 2.3E-21 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF13177 DNA polymerase III, delta subunit 629 709 6.1E-11 T 23-10-2018 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF51294 59 599 4.51E-43 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF14528 LAGLIDADG-like domain 185 253 1.1E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Pfam PF14528 LAGLIDADG-like domain 273 345 1.0E-12 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 SUPERFAMILY SSF47413 440 483 5.07E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:3.10.28.10 179 344 5.2E-27 T 23-10-2018 IPR027434 Homing endonuclease TAM4_294 b28a700a10bfb7b6d5b2e30dd9c33251 870 Gene3D G3DSA:2.170.16.10 64 178 4.0E-24 T 23-10-2018 TAM4_452 0e0599ea235db872bf3ade7feab689dd 165 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 134 1.6E-44 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TAM4_452 0e0599ea235db872bf3ade7feab689dd 165 SUPERFAMILY SSF118196 1 149 2.88E-54 T 23-10-2018 IPR036413 YaeB-like superfamily TAM4_452 0e0599ea235db872bf3ade7feab689dd 165 Gene3D G3DSA:2.40.30.70 4 149 1.4E-50 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily TAM4_452 0e0599ea235db872bf3ade7feab689dd 165 ProSitePatterns PS01318 TsaA-like domain signature. 80 91 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TAM4_452 0e0599ea235db872bf3ade7feab689dd 165 Pfam PF01980 Uncharacterised protein family UPF0066 20 132 2.5E-41 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TAM4_766 c78d0b6453f1fe2cb52637c1c6b82e33 174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_766 c78d0b6453f1fe2cb52637c1c6b82e33 174 SUPERFAMILY SSF54862 13 138 3.66E-49 T 23-10-2018 TAM4_766 c78d0b6453f1fe2cb52637c1c6b82e33 174 Pfam PF13247 4Fe-4S dicluster domain 33 124 9.2E-28 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_766 c78d0b6453f1fe2cb52637c1c6b82e33 174 Gene3D G3DSA:3.30.70.20 14 165 1.2E-47 T 23-10-2018 TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 SUPERFAMILY SSF54980 153 223 6.96E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 SUPERFAMILY SSF89895 2 83 1.01E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 SUPERFAMILY SSF109728 78 151 2.35E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 Gene3D G3DSA:3.30.1250.10 4 83 2.3E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 33 52 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 Gene3D G3DSA:3.30.70.240 159 231 1.7E-28 T 23-10-2018 TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 Gene3D G3DSA:1.10.10.900 84 158 2.2E-30 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 Pfam PF09377 SBDS protein C-terminal domain 97 197 6.0E-18 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 2 227 2.0E-90 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 TAM4_190 4320e61daadcfb60223ccfa4cf4626a0 232 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 4 90 3.3E-26 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal TAM4_1510 c7797abb8030084d8bd40e0d19447e56 67 Gene3D G3DSA:1.10.10.60 11 54 1.2E-8 T 23-10-2018 TAM4_1510 c7797abb8030084d8bd40e0d19447e56 67 SUPERFAMILY SSF46689 11 52 7.17E-7 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TAM4_1510 c7797abb8030084d8bd40e0d19447e56 67 Pfam PF13384 Homeodomain-like domain 22 57 2.4E-6 T 23-10-2018 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 1.1E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 461 6.7E-268 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 7.5E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 PIRSF PIRSF039114 1 463 2.1E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 SUPERFAMILY SSF47917 363 420 7.59E-10 T 23-10-2018 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 SUPERFAMILY SSF52540 79 355 3.54E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.656 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1370 303eb7214000de0f6dcb283bffbfbcda 463 Gene3D G3DSA:3.40.50.12240 2 459 1.0E-195 T 23-10-2018 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Pfam PF01131 DNA topoisomerase 156 564 1.5E-135 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 SUPERFAMILY SSF56712 2 653 2.88E-165 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 641 678 2.0E-13 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Gene3D G3DSA:1.10.460.10 163 575 1.8E-126 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 322 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 SMART SM00436 131 226 6.0E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 710 51.462 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 SMART SM00437 271 527 1.4E-107 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Gene3D G3DSA:2.70.20.10 220 475 1.8E-126 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 SUPERFAMILY SSF57783 641 680 1.02E-5 T 23-10-2018 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Pfam PF01751 Toprim domain 3 139 1.5E-18 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 671 4.1E-288 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 1.5E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 1.5E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 1.5E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 1.5E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 1.5E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 SMART SM00493 2 129 3.7E-19 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Gene3D G3DSA:3.40.50.140 1 154 9.9E-31 T 23-10-2018 TAM4_1864 0fb410cc2da2952154618f9d514fe363 719 Gene3D G3DSA:1.10.290.10 279 406 1.8E-126 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TAM4_669 ae11affeb49bc561e247684415f048b3 221 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 214 1.0E-72 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 TAM4_669 ae11affeb49bc561e247684415f048b3 221 SMART SM00220 1 220 5.5E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_669 ae11affeb49bc561e247684415f048b3 221 Gene3D G3DSA:1.10.510.10 97 216 1.3E-33 T 23-10-2018 TAM4_669 ae11affeb49bc561e247684415f048b3 221 Gene3D G3DSA:3.30.200.20 18 89 2.4E-25 T 23-10-2018 TAM4_669 ae11affeb49bc561e247684415f048b3 221 SUPERFAMILY SSF56112 11 190 1.89E-30 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_669 ae11affeb49bc561e247684415f048b3 221 Pfam PF01163 RIO1 family 51 148 5.0E-16 T 23-10-2018 TAM4_669 ae11affeb49bc561e247684415f048b3 221 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 125 137 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TAM4_1862 adac51726e61f9bb8666350a37584812 125 SUPERFAMILY SSF88723 1 118 2.69E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1862 adac51726e61f9bb8666350a37584812 125 Pfam PF01850 PIN domain 4 119 2.6E-13 T 23-10-2018 IPR002716 PIN domain TAM4_1862 adac51726e61f9bb8666350a37584812 125 Gene3D G3DSA:3.40.50.1010 4 123 7.4E-16 T 23-10-2018 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Gene3D G3DSA:3.40.120.10 1 145 4.8E-46 T 23-10-2018 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 86 100 2.1E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 239 2.1E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 196 209 2.1E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 162 181 2.1E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Gene3D G3DSA:3.40.120.10 160 342 6.8E-50 T 23-10-2018 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 SUPERFAMILY SSF53738 248 350 3.34E-12 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 SUPERFAMILY SSF53738 146 247 2.98E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 87 96 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 439 2.7E-149 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Gene3D G3DSA:3.40.120.10 245 344 6.8E-50 T 23-10-2018 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 SUPERFAMILY SSF53738 2 168 1.29E-41 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Gene3D G3DSA:3.30.310.50 357 449 2.6E-18 T 23-10-2018 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 367 432 3.8E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 128 4.2E-39 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 SUPERFAMILY SSF55957 343 446 3.66E-22 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 148 244 4.0E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_903 5e65e9837e0db89ade86e43a6267853c 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 249 352 4.2E-9 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_1552 c92ec1682c4c6dac45f6ebfedc6554d5 266 Gene3D G3DSA:2.40.50.140 20 141 5.1E-13 T 23-10-2018 TAM4_1552 c92ec1682c4c6dac45f6ebfedc6554d5 266 SUPERFAMILY SSF50249 36 131 9.71E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1552 c92ec1682c4c6dac45f6ebfedc6554d5 266 Gene3D G3DSA:1.10.10.10 197 264 5.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1552 c92ec1682c4c6dac45f6ebfedc6554d5 266 Pfam PF01336 OB-fold nucleic acid binding domain 45 113 1.7E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_999 73f335b2230cf48322297e3175baa231 402 Pfam PF13173 AAA domain 44 177 3.2E-18 T 23-10-2018 TAM4_999 73f335b2230cf48322297e3175baa231 402 SMART SM00382 41 167 0.004 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_999 73f335b2230cf48322297e3175baa231 402 Gene3D G3DSA:3.40.50.300 20 142 1.1E-7 T 23-10-2018 TAM4_999 73f335b2230cf48322297e3175baa231 402 SUPERFAMILY SSF52540 41 217 2.48E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1684 a5d37bb926cbc93f72786615bf2ff0aa 497 Pfam PF07690 Major Facilitator Superfamily 27 420 1.2E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1684 a5d37bb926cbc93f72786615bf2ff0aa 497 Gene3D G3DSA:1.20.1720.10 19 222 1.2E-46 T 23-10-2018 TAM4_1684 a5d37bb926cbc93f72786615bf2ff0aa 497 Gene3D G3DSA:1.20.1250.20 268 479 2.6E-13 T 23-10-2018 TAM4_1684 a5d37bb926cbc93f72786615bf2ff0aa 497 SUPERFAMILY SSF103473 16 480 8.11E-68 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1177 5c16621d51808889247fa45c2e050b51 513 Pfam PF00361 Proton-conducting membrane transporter 136 436 2.8E-62 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1177 5c16621d51808889247fa45c2e050b51 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 1.1E-15 T 23-10-2018 TAM4_1177 5c16621d51808889247fa45c2e050b51 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 1.1E-15 T 23-10-2018 TAM4_1177 5c16621d51808889247fa45c2e050b51 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.1E-15 T 23-10-2018 TAM4_1177 5c16621d51808889247fa45c2e050b51 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 1.1E-15 T 23-10-2018 TAM4_1177 5c16621d51808889247fa45c2e050b51 513 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 122 1.4E-11 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_2380 702c96cc0ce8102f18236d513655dc92 154 Pfam PF01850 PIN domain 5 137 2.6E-15 T 23-10-2018 IPR002716 PIN domain TAM4_2380 702c96cc0ce8102f18236d513655dc92 154 SUPERFAMILY SSF88723 2 137 1.4E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2380 702c96cc0ce8102f18236d513655dc92 154 Gene3D G3DSA:3.40.50.1010 3 150 1.4E-12 T 23-10-2018 TAM4_2380 702c96cc0ce8102f18236d513655dc92 154 SMART SM00670 2 136 2.5E-9 T 23-10-2018 IPR002716 PIN domain TAM4_2054 aa761c9e475fae13ff3efa1194beb7e7 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 40 4.7E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2054 aa761c9e475fae13ff3efa1194beb7e7 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 43 2.2E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2054 aa761c9e475fae13ff3efa1194beb7e7 82 Gene3D G3DSA:2.10.260.10 3 40 3.2E-14 T 23-10-2018 TAM4_2054 aa761c9e475fae13ff3efa1194beb7e7 82 SUPERFAMILY SSF89447 3 44 1.46E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_2054 aa761c9e475fae13ff3efa1194beb7e7 82 SMART SM00966 2 47 7.6E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 3.3E-18 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 SUPERFAMILY SSF52080 5 147 1.31E-32 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.244 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 Gene3D G3DSA:3.100.10.10 63 148 2.5E-20 T 23-10-2018 TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 Gene3D G3DSA:4.10.990.10 4 53 6.0E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal TAM4_367 97cccd3ef4edecbf266fdcfe042b636b 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_451 280be6b7e118a18ef9be2577e9bb517e 266 Gene3D G3DSA:3.40.50.10900 1 244 4.6E-76 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TAM4_451 280be6b7e118a18ef9be2577e9bb517e 266 Pfam PF09754 PAC2 family 19 242 3.4E-49 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TAM4_451 280be6b7e118a18ef9be2577e9bb517e 266 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 12 265 6.0E-75 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 TAM4_451 280be6b7e118a18ef9be2577e9bb517e 266 SUPERFAMILY SSF159659 2 253 7.85E-47 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF01131 DNA topoisomerase 1449 1697 1.2E-50 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF01131 DNA topoisomerase 820 961 2.3E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:1.10.290.10 924 960 5.0E-24 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:2.170.16.10 966 1078 1.7E-13 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:1.10.460.10 1605 1692 2.1E-58 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:3.40.50.140 630 819 1.3E-29 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1704 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF55608 1233 1316 5.29E-11 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF52540 326 624 4.76E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1429 1449 2.1E-4 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF14890 Intein splicing domain 968 1448 8.0E-37 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:2.70.20.10 875 923 5.0E-24 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00493 642 795 5.0E-46 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:3.10.28.10 1153 1310 3.3E-14 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF00270 DEAD/DEAH box helicase 88 222 1.8E-12 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 2.0E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 2.0E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1446 1455 2.0E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1621 1635 2.0E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1527 1543 2.0E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00487 81 331 9.7E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF56712 1448 1704 1.96E-58 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:1.10.290.10 1443 1541 2.1E-58 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:1.10.460.10 828 874 5.0E-24 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00306 959 1059 1.3E-22 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Hamap MF_01125 Reverse gyrase [rgy]. 1 1708 58.309 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00437 916 1660 2.8E-93 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF56712 637 961 2.62E-76 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF01751 Toprim domain 644 805 4.8E-29 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00305 1409 1454 1.1E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:3.40.50.300 545 629 1.7E-15 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:3.40.50.300 320 503 3.8E-33 T 23-10-2018 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Gene3D G3DSA:2.70.20.10 1542 1604 2.1E-58 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF51294 961 1448 2.98E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 Pfam PF14528 LAGLIDADG-like domain 1240 1316 2.3E-9 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 961 1035 3.4E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SMART SM00436 796 883 3.5E-39 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TAM4_1673 14bdc644d257f6cdcf33849800115d43 1714 SUPERFAMILY SSF52540 41 242 1.11E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1619 1480c52ee7e02dc3647325cd7b31ce59 182 Pfam PF06197 Protein of unknown function (DUF998) 15 175 1.2E-11 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 PIRSF PIRSF001021 25 475 1.0E-112 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 PRINTS PR00110 Alpha-amylase signature 139 150 4.6E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 PRINTS PR00110 Alpha-amylase signature 318 330 4.6E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 PRINTS PR00110 Alpha-amylase signature 231 242 4.6E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 SUPERFAMILY SSF51011 401 475 1.5E-30 T 23-10-2018 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 SUPERFAMILY SSF51445 47 399 2.46E-71 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 Gene3D G3DSA:2.60.40.1180 377 475 7.6E-51 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 Pfam PF09154 Domain of unknown function (DUF1939) 403 470 2.2E-21 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 Pfam PF00128 Alpha amylase, catalytic domain 69 352 6.8E-14 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 SMART SM00642 49 394 1.8E-30 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_1203 40e7e9a3fea74139fa1a57082eb3b58f 475 Gene3D G3DSA:3.20.20.80 40 376 2.6E-107 T 23-10-2018 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 SUPERFAMILY SSF52418 155 405 3.4E-70 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 PIRSF PIRSF000478 84 502 1.1E-124 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Gene3D G3DSA:3.40.1030.10 152 412 3.6E-103 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 SMART SM00941 424 491 2.6E-25 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 1.8E-229 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Gene3D G3DSA:1.20.970.10 84 151 4.1E-24 T 23-10-2018 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 SUPERFAMILY SSF47648 86 153 1.44E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Gene3D G3DSA:2.40.40.20 1 83 2.5E-36 T 23-10-2018 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 387 1.2E-15 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 7.7E-15 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 SUPERFAMILY SSF54680 412 495 3.4E-19 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Gene3D G3DSA:3.90.1170.30 413 493 2.4E-29 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 9.0E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 Hamap MF_02132 AMP phosphorylase. 1 503 47.187 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 SUPERFAMILY SSF50692 9 62 5.88E-5 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_270 f167ab5902b3af0a58f80f5304c6bb66 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 2.8E-245 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 Gene3D G3DSA:3.40.1010.10 1 114 1.3E-41 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 Gene3D G3DSA:3.30.950.10 115 264 1.2E-54 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.788 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 2.9E-105 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 PIRSF PIRSF036432 2 260 4.3E-101 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 SUPERFAMILY SSF53790 1 259 1.7E-64 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TAM4_1375 aadf2427467c803a23c191fd8672a91f 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 219 3.4E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 806 48.198 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 1.1E-32 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Gene3D G3DSA:3.40.50.11040 25 258 9.0E-12 T 23-10-2018 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Pfam PF05127 Helicase 284 457 4.2E-54 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Gene3D G3DSA:3.40.50.12320 280 447 1.3E-33 T 23-10-2018 TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 SUPERFAMILY SSF55729 489 643 7.59E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 SUPERFAMILY SSF52540 259 396 2.77E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Pfam PF13718 GNAT acetyltransferase 2 497 614 2.2E-32 T 23-10-2018 IPR000182 GNAT domain TAM4_2097 5b931a7e537971fe26d4fa45f4c24bd0 811 Gene3D G3DSA:3.40.630.30 456 661 2.8E-55 T 23-10-2018 TAM4_1812 66d8f039f3ed1ec695753892762e9fd1 246 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 228 246 8.0E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1267 ec3da7ca1a2f0208c93b2caa0559b742 275 SMART SM00729 13 216 7.3E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1267 ec3da7ca1a2f0208c93b2caa0559b742 275 SUPERFAMILY SSF102114 12 239 1.07E-28 T 23-10-2018 TAM4_1267 ec3da7ca1a2f0208c93b2caa0559b742 275 Gene3D G3DSA:3.20.20.70 6 220 5.1E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1267 ec3da7ca1a2f0208c93b2caa0559b742 275 Pfam PF04055 Radical SAM superfamily 21 159 1.0E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1977 a0eadacfaee6f213b48867b6941ac8a8 152 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 14 115 8.6E-19 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_1977 a0eadacfaee6f213b48867b6941ac8a8 152 Pfam PF03334 Na+/H+ antiporter subunit 15 101 3.2E-15 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_228 2d900b89d456631b8b39523857c9aeac 321 SUPERFAMILY SSF52540 2 295 1.07E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_228 2d900b89d456631b8b39523857c9aeac 321 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 13 313 2.2E-125 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TAM4_228 2d900b89d456631b8b39523857c9aeac 321 Pfam PF03308 ArgK protein 18 283 3.1E-103 T 23-10-2018 TAM4_228 2d900b89d456631b8b39523857c9aeac 321 Gene3D G3DSA:3.40.50.300 41 252 4.9E-86 T 23-10-2018 TAM4_228 2d900b89d456631b8b39523857c9aeac 321 SMART SM00382 45 189 1.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_300 9a281769c2ae53d4b388346052932a44 260 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TAM4_300 9a281769c2ae53d4b388346052932a44 260 SMART SM00662 14 254 2.8E-84 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.597 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Gene3D G3DSA:3.30.1360.10 6 251 1.3E-95 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 3.2E-27 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Gene3D G3DSA:2.170.120.12 40 147 1.3E-95 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 SUPERFAMILY SSF55257 3 257 1.33E-28 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Gene3D G3DSA:3.30.70.3110 157 218 1.3E-95 T 23-10-2018 TAM4_300 9a281769c2ae53d4b388346052932a44 260 SUPERFAMILY SSF56553 39 149 1.24E-28 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_300 9a281769c2ae53d4b388346052932a44 260 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 4.0E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_171 04d45073491a257d09d0104e3effa514 67 Pfam PF01954 Protein of unknown function DUF104 2 53 4.1E-17 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_171 04d45073491a257d09d0104e3effa514 67 Gene3D G3DSA:4.10.1150.10 1 62 1.9E-17 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_171 04d45073491a257d09d0104e3effa514 67 SUPERFAMILY SSF141694 1 59 2.12E-15 T 23-10-2018 TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 SUPERFAMILY SSF52540 22 272 1.57E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 Pfam PF13173 AAA domain 39 189 7.3E-8 T 23-10-2018 TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 Gene3D G3DSA:1.10.10.10 299 372 1.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 Gene3D G3DSA:3.40.50.300 5 208 9.6E-28 T 23-10-2018 TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 Gene3D G3DSA:1.10.8.60 210 292 6.7E-10 T 23-10-2018 TAM4_2133 8e4636417fcda4591ae25f231cfd2c4b 382 SUPERFAMILY SSF46785 296 371 8.17E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1615 d331cc15c6e61ef8c39d089feaa887eb 303 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 264 7.5E-40 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TAM4_1710 52ea4da4c94bc763e399da440aa0ff12 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 1.0E-108 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TAM4_1710 52ea4da4c94bc763e399da440aa0ff12 252 SUPERFAMILY SSF51366 1 249 1.73E-83 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_1710 52ea4da4c94bc763e399da440aa0ff12 252 Pfam PF00977 Histidine biosynthesis protein 5 233 1.5E-87 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TAM4_1710 52ea4da4c94bc763e399da440aa0ff12 252 Gene3D G3DSA:3.20.20.70 1 252 6.2E-106 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1710 52ea4da4c94bc763e399da440aa0ff12 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 47.684 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TAM4_1627 c302f561a69c37672c3821e52f6e0858 102 Gene3D G3DSA:3.30.1330.30 1 101 2.8E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_1627 c302f561a69c37672c3821e52f6e0858 102 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 3.8E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TAM4_1627 c302f561a69c37672c3821e52f6e0858 102 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.66 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1627 c302f561a69c37672c3821e52f6e0858 102 SUPERFAMILY SSF55315 3 97 5.62E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_1627 c302f561a69c37672c3821e52f6e0858 102 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1570 85d407e494c220802a1281114ab2e926 154 Pfam PF01850 PIN domain 1 141 2.9E-19 T 23-10-2018 IPR002716 PIN domain TAM4_1570 85d407e494c220802a1281114ab2e926 154 SUPERFAMILY SSF88723 1 143 4.21E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1570 85d407e494c220802a1281114ab2e926 154 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 150 9.605 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_1570 85d407e494c220802a1281114ab2e926 154 SMART SM00670 1 142 5.4E-5 T 23-10-2018 IPR002716 PIN domain TAM4_1570 85d407e494c220802a1281114ab2e926 154 Gene3D G3DSA:3.40.50.1010 1 147 6.3E-15 T 23-10-2018 TAM4_1205 e61da6bcf3224ce7aece9b69e43ca002 702 Pfam PF07885 Ion channel 618 699 1.2E-13 T 23-10-2018 IPR013099 Potassium channel domain TAM4_1205 e61da6bcf3224ce7aece9b69e43ca002 702 SUPERFAMILY SSF81324 643 701 1.57E-14 T 23-10-2018 TAM4_1205 e61da6bcf3224ce7aece9b69e43ca002 702 Pfam PF13576 Pentapeptide repeats (9 copies) 96 136 2.0E-6 T 23-10-2018 IPR001646 Pentapeptide repeat TAM4_1205 e61da6bcf3224ce7aece9b69e43ca002 702 Gene3D G3DSA:1.10.287.70 602 702 5.6E-14 T 23-10-2018 TAM4_2023 3b6e58308ccdb972aac9262cc02a6218 100 Pfam PF02915 Rubrerythrin 24 91 4.3E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2023 3b6e58308ccdb972aac9262cc02a6218 100 SUPERFAMILY SSF47240 6 85 1.65E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_2023 3b6e58308ccdb972aac9262cc02a6218 100 Gene3D G3DSA:1.20.1260.10 7 72 9.7E-11 T 23-10-2018 IPR012347 Ferritin-like TAM4_944 e2545f2c7a72cb8453e45c0789711bfc 189 SUPERFAMILY SSF88697 1 103 1.06E-22 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_944 e2545f2c7a72cb8453e45c0789711bfc 189 SMART SM01022 4 104 4.9E-26 T 23-10-2018 IPR007374 ASCH domain TAM4_944 e2545f2c7a72cb8453e45c0789711bfc 189 Pfam PF04266 ASCH domain 4 104 5.7E-19 T 23-10-2018 IPR007374 ASCH domain TAM4_810 533b5e23683bfec96911f8ab5076ccc3 70 Gene3D G3DSA:4.10.1150.10 2 63 3.9E-11 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_810 533b5e23683bfec96911f8ab5076ccc3 70 Pfam PF01954 Protein of unknown function DUF104 3 49 6.5E-18 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_810 533b5e23683bfec96911f8ab5076ccc3 70 SUPERFAMILY SSF141694 3 46 3.92E-13 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.170.16.10 1040 1102 9.8E-10 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:3.30.1640.10 1 99 9.0E-39 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF00493 MCM2/3/5 family 1108 1131 5.8E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF00493 MCM2/3/5 family 513 576 4.1E-19 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF00493 MCM2/3/5 family 265 335 1.0E-21 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF00493 MCM2/3/5 family 1461 1641 3.9E-65 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR00379 Intein signature 419 432 3.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR00379 Intein signature 1084 1101 3.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR00379 Intein signature 898 910 3.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR00379 Intein signature 1102 1111 3.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR00379 Intein signature 794 806 3.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF14890 Intein splicing domain 470 519 5.5E-10 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00305 478 525 7.4E-16 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00305 1067 1113 1.1E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00305 1420 1468 0.0025 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF14890 Intein splicing domain 342 460 1.3E-19 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF51294 335 520 4.91E-43 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF51294 1133 1463 1.29E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.170.16.10 1137 1283 2.0E-34 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00306 1129 1251 3.8E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00306 573 689 2.5E-16 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00306 333 456 2.7E-33 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:3.40.50.300 1103 1136 2.7E-8 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SMART SM00350 100 1642 9.3E-25 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF52540 1461 1638 1.02E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF50249 10 247 5.82E-65 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 564 578 3.8E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 319 334 3.8E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF17207 MCM OB domain 104 229 5.2E-36 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:1.10.10.10 1646 1731 6.2E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.170.16.10 335 521 2.0E-52 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.170.16.10 1394 1459 1.3E-9 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF14551 MCM N-terminal domain 9 81 9.9E-14 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF55608 889 982 4.16E-9 T 23-10-2018 IPR027434 Homing endonuclease TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 335 432 1.8E-21 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1137 1227 3.0E-13 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 575 665 1.2E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1441 1463 4.9E-5 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1086 1108 1.8E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_323 2e672d6909599162488cc093741ce57e 1731 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 498 520 1.4E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.40.50.140 176 256 6.1E-27 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:3.10.28.10 790 972 2.7E-16 T 23-10-2018 IPR027434 Homing endonuclease TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:3.40.50.300 1460 1645 7.1E-69 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:3.40.50.300 262 334 1.2E-22 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.20.28.10 131 175 2.1E-29 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF14890 Intein splicing domain 582 1107 1.2E-30 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 SUPERFAMILY SSF51294 575 1107 1.49E-34 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Gene3D G3DSA:2.170.16.10 573 704 3.9E-20 T 23-10-2018 TAM4_323 2e672d6909599162488cc093741ce57e 1731 Pfam PF14890 Intein splicing domain 1139 1462 3.7E-18 T 23-10-2018 TAM4_1777 8c0aedcb66d1a5d5455ee72a8d9e3a67 241 SUPERFAMILY SSF56784 2 205 1.23E-12 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1795 8d2d366be489cbbe58b3b2d98cba7b30 324 PIRSF PIRSF002849 2 319 2.2E-125 T 23-10-2018 TAM4_1795 8d2d366be489cbbe58b3b2d98cba7b30 324 Gene3D G3DSA:3.40.50.300 21 187 1.1E-44 T 23-10-2018 TAM4_1795 8d2d366be489cbbe58b3b2d98cba7b30 324 SUPERFAMILY SSF52540 9 289 4.72E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1795 8d2d366be489cbbe58b3b2d98cba7b30 324 Gene3D G3DSA:1.10.8.300 205 314 8.6E-31 T 23-10-2018 TAM4_1795 8d2d366be489cbbe58b3b2d98cba7b30 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 170 1.0E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 5.9E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 SUPERFAMILY SSF52540 4 209 1.84E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 2.6E-206 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Gene3D G3DSA:2.40.30.10 204 318 2.8E-46 T 23-10-2018 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Gene3D G3DSA:3.40.50.300 3 203 7.5E-69 T 23-10-2018 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Gene3D G3DSA:2.40.30.10 319 410 9.8E-35 T 23-10-2018 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 1.6E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.29 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 1.1E-36 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 SUPERFAMILY SSF50447 203 316 3.33E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 SUPERFAMILY SSF50465 317 409 1.22E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TAM4_2209 69244065e8ad74b16bfd7698e040309e 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 195 4.4E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_1659 30b3d12c5ef3901a8527dc78900495f2 311 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 5.2E-16 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TAM4_1659 30b3d12c5ef3901a8527dc78900495f2 311 Gene3D G3DSA:3.10.50.80 3 164 3.2E-51 T 23-10-2018 TAM4_1659 30b3d12c5ef3901a8527dc78900495f2 311 SUPERFAMILY SSF54534 3 156 2.36E-40 T 23-10-2018 TAM4_41 d06a8e07f979e6591af8d819233b96a9 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 188 3.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_41 d06a8e07f979e6591af8d819233b96a9 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 193 9.9E-18 T 23-10-2018 TAM4_41 d06a8e07f979e6591af8d819233b96a9 233 Gene3D G3DSA:3.40.50.1000 3 216 2.0E-36 T 23-10-2018 IPR023214 HAD superfamily TAM4_41 d06a8e07f979e6591af8d819233b96a9 233 SUPERFAMILY SSF56784 3 222 1.22E-38 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_41 d06a8e07f979e6591af8d819233b96a9 233 Gene3D G3DSA:1.10.150.520 14 96 2.0E-36 T 23-10-2018 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 Gene3D G3DSA:3.40.50.1370 138 297 1.7E-139 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 1.4E-146 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 SUPERFAMILY SSF53671 4 313 3.27E-117 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 86.095 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 4.8E-67 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.4E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 7.7E-30 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.7E-30 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.7E-30 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 7.7E-30 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 Gene3D G3DSA:3.40.50.1370 10 307 1.7E-139 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_1861 42751ab5f2d48252b9a35c9137ffbad7 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_1445 8cbb82e87af53c4eca1dca6206128684 125 SMART SM00748 7 113 5.9E-17 T 23-10-2018 IPR007842 HEPN domain TAM4_1445 8cbb82e87af53c4eca1dca6206128684 125 Pfam PF05168 HEPN domain 4 117 1.9E-31 T 23-10-2018 IPR007842 HEPN domain TAM4_1445 8cbb82e87af53c4eca1dca6206128684 125 Gene3D G3DSA:1.20.120.330 1 121 2.5E-33 T 23-10-2018 TAM4_1445 8cbb82e87af53c4eca1dca6206128684 125 SUPERFAMILY SSF81593 5 117 1.53E-27 T 23-10-2018 TAM4_88 c0369dd38f87d52b840b537db13f8226 363 Gene3D G3DSA:3.40.50.2000 3 193 2.0E-11 T 23-10-2018 TAM4_88 c0369dd38f87d52b840b537db13f8226 363 Gene3D G3DSA:3.40.50.2000 194 342 2.1E-17 T 23-10-2018 TAM4_88 c0369dd38f87d52b840b537db13f8226 363 SUPERFAMILY SSF53756 3 356 3.52E-36 T 23-10-2018 TAM4_88 c0369dd38f87d52b840b537db13f8226 363 Pfam PF13692 Glycosyl transferases group 1 199 324 5.5E-18 T 23-10-2018 TAM4_88 c0369dd38f87d52b840b537db13f8226 363 Pfam PF13439 Glycosyltransferase Family 4 56 187 2.2E-10 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TAM4_2025 00f751b73c115743d25ada2c07956a88 182 Pfam PF02441 Flavoprotein 6 160 2.4E-28 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TAM4_2025 00f751b73c115743d25ada2c07956a88 182 SUPERFAMILY SSF52507 6 178 1.57E-56 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TAM4_2025 00f751b73c115743d25ada2c07956a88 182 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 178 5.2E-70 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TAM4_2025 00f751b73c115743d25ada2c07956a88 182 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 180 36.756 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TAM4_2025 00f751b73c115743d25ada2c07956a88 182 Gene3D G3DSA:3.40.50.1950 2 181 2.3E-71 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TAM4_804 930eddc94c0d21941917757816eb5087 887 Pfam PF00271 Helicase conserved C-terminal domain 430 546 8.9E-14 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_804 930eddc94c0d21941917757816eb5087 887 SMART SM00490 463 548 2.5E-19 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_804 930eddc94c0d21941917757816eb5087 887 Pfam PF00270 DEAD/DEAH box helicase 229 392 1.5E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_804 930eddc94c0d21941917757816eb5087 887 Gene3D G3DSA:3.40.50.300 414 631 2.8E-29 T 23-10-2018 TAM4_804 930eddc94c0d21941917757816eb5087 887 SUPERFAMILY SSF52540 237 562 2.95E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_804 930eddc94c0d21941917757816eb5087 887 SMART SM00487 223 420 1.2E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_804 930eddc94c0d21941917757816eb5087 887 Gene3D G3DSA:3.40.50.300 211 412 3.2E-51 T 23-10-2018 TAM4_36 84ab062e19e1719a22d50ec1872374da 392 Gene3D G3DSA:3.90.1150.10 34 384 1.1E-131 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_36 84ab062e19e1719a22d50ec1872374da 392 Pfam PF00155 Aminotransferase class I and II 34 384 2.9E-73 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_36 84ab062e19e1719a22d50ec1872374da 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TAM4_36 84ab062e19e1719a22d50ec1872374da 392 SUPERFAMILY SSF53383 9 391 6.72E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_36 84ab062e19e1719a22d50ec1872374da 392 Gene3D G3DSA:3.40.640.10 65 284 1.1E-131 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_13 e480a8e574dac9169f6a636c205a5826 257 Pfam PF13614 AAA domain 4 178 7.8E-53 T 23-10-2018 IPR025669 AAA domain TAM4_13 e480a8e574dac9169f6a636c205a5826 257 SUPERFAMILY SSF52540 1 253 1.17E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_13 e480a8e574dac9169f6a636c205a5826 257 PIRSF PIRSF009320 2 47 3.6E-14 T 23-10-2018 TAM4_13 e480a8e574dac9169f6a636c205a5826 257 PIRSF PIRSF009320 91 257 7.9E-7 T 23-10-2018 TAM4_13 e480a8e574dac9169f6a636c205a5826 257 Gene3D G3DSA:3.40.50.300 1 255 3.4E-72 T 23-10-2018 TAM4_1147 5d03c77c149545c0ee293a52007bcf84 388 Pfam PF01266 FAD dependent oxidoreductase 4 355 8.2E-75 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TAM4_1147 5d03c77c149545c0ee293a52007bcf84 388 SUPERFAMILY SSF51905 2 378 5.18E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1147 5d03c77c149545c0ee293a52007bcf84 388 SUPERFAMILY SSF54373 225 318 1.09E-7 T 23-10-2018 TAM4_1147 5d03c77c149545c0ee293a52007bcf84 388 Gene3D G3DSA:3.30.9.10 82 317 1.1E-117 T 23-10-2018 TAM4_1147 5d03c77c149545c0ee293a52007bcf84 388 Gene3D G3DSA:3.50.50.60 4 359 1.1E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1906 b941329be7def3d2782f7ecad7ffbc77 387 Pfam PF13847 Methyltransferase domain 90 155 3.2E-8 T 23-10-2018 IPR025714 Methyltransferase domain TAM4_1906 b941329be7def3d2782f7ecad7ffbc77 387 SUPERFAMILY SSF53335 57 165 7.85E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1906 b941329be7def3d2782f7ecad7ffbc77 387 Gene3D G3DSA:3.40.50.150 39 240 2.1E-25 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Gene3D G3DSA:3.40.50.300 8 200 2.2E-74 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Pfam PF00271 Helicase conserved C-terminal domain 230 372 2.5E-9 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SMART SM00487 20 204 7.8E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SMART SM00490 288 374 2.4E-14 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SUPERFAMILY SSF46785 405 492 1.01E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Pfam PF14520 Helix-hairpin-helix domain 646 694 1.9E-11 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.502 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SUPERFAMILY SSF52540 2 191 2.1E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SUPERFAMILY SSF52540 196 393 6.54E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Gene3D G3DSA:1.10.150.20 660 690 1.3E-7 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Gene3D G3DSA:3.40.50.300 201 399 1.8E-61 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Pfam PF00270 DEAD/DEAH box helicase 26 180 4.2E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SMART SM00278 645 664 0.43 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SMART SM00278 678 697 17.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Gene3D G3DSA:1.10.10.10 408 491 4.8E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 Gene3D G3DSA:1.10.3380.20 492 659 4.3E-55 T 23-10-2018 TAM4_712 b13bcfa51f945f41e3d88cfafab0e7d0 720 SUPERFAMILY SSF158702 493 700 6.54E-59 T 23-10-2018 TAM4_606 aab91301e423143a910a95483b2cd905 195 Gene3D G3DSA:2.40.50.140 66 154 8.8E-22 T 23-10-2018 TAM4_606 aab91301e423143a910a95483b2cd905 195 Gene3D G3DSA:2.40.50.100 11 60 1.1E-15 T 23-10-2018 TAM4_606 aab91301e423143a910a95483b2cd905 195 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 192 27.642 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 TAM4_606 aab91301e423143a910a95483b2cd905 195 SUPERFAMILY SSF110324 12 63 5.23E-12 T 23-10-2018 TAM4_606 aab91301e423143a910a95483b2cd905 195 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 7.5E-9 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_606 aab91301e423143a910a95483b2cd905 195 Gene3D G3DSA:2.20.70.10 155 188 6.5E-18 T 23-10-2018 TAM4_606 aab91301e423143a910a95483b2cd905 195 SUPERFAMILY SSF50249 64 185 3.19E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_606 aab91301e423143a910a95483b2cd905 195 SMART SM00316 68 148 4.0E-8 T 23-10-2018 IPR022967 RNA-binding domain, S1 TAM4_1778 8d217a833ecacb9e84468c10bfbc09e3 178 Gene3D G3DSA:3.40.630.30 5 177 3.2E-46 T 23-10-2018 TAM4_1778 8d217a833ecacb9e84468c10bfbc09e3 178 SUPERFAMILY SSF55729 3 171 8.15E-42 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1778 8d217a833ecacb9e84468c10bfbc09e3 178 Pfam PF13302 Acetyltransferase (GNAT) domain 18 147 1.1E-26 T 23-10-2018 IPR000182 GNAT domain TAM4_1949 b0235a2a756cceaa68ff4ccef03e7961 268 PIRSF PIRSF019073 1 268 9.3E-76 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TAM4_1949 b0235a2a756cceaa68ff4ccef03e7961 268 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 134 257 5.8E-22 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TAM4_1949 b0235a2a756cceaa68ff4ccef03e7961 268 Gene3D G3DSA:3.40.1700.10 175 266 2.6E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TAM4_1949 b0235a2a756cceaa68ff4ccef03e7961 268 SUPERFAMILY SSF143597 109 261 3.14E-29 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TAM4_1949 b0235a2a756cceaa68ff4ccef03e7961 268 Hamap MF_00840 Diadenylate cyclase [dacZ]. 5 267 32.957 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 SUPERFAMILY SSF46785 14 84 4.8E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 Gene3D G3DSA:1.10.10.10 2 84 3.4E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 Pfam PF13463 Winged helix DNA-binding domain 18 69 4.1E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 Pfam PF01982 Domain of unknown function DUF120 93 209 2.3E-38 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 SMART SM00347 6 93 0.0063 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 SUPERFAMILY SSF82114 89 209 1.63E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 Gene3D G3DSA:2.40.30.30 88 212 4.6E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TAM4_500 76b9531010f717e54c4d4953cf1173ad 214 Hamap MF_01285 Riboflavin kinase [ribK]. 87 210 25.013 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TAM4_180 1c59ffef59ef9cb01101c70a9bb7bbfa 281 Gene3D G3DSA:3.20.20.140 3 281 4.8E-27 T 23-10-2018 TAM4_180 1c59ffef59ef9cb01101c70a9bb7bbfa 281 Pfam PF01026 TatD related DNase 5 275 1.6E-30 T 23-10-2018 IPR001130 TatD family GO:0016788 TAM4_180 1c59ffef59ef9cb01101c70a9bb7bbfa 281 PIRSF PIRSF004961 1 281 1.8E-124 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 TAM4_180 1c59ffef59ef9cb01101c70a9bb7bbfa 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 1.0E-84 T 23-10-2018 TAM4_180 1c59ffef59ef9cb01101c70a9bb7bbfa 281 SUPERFAMILY SSF51556 1 278 1.75E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 SUPERFAMILY SSF54862 298 340 9.21E-12 T 23-10-2018 TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 26 194 4.7E-37 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 SUPERFAMILY SSF52402 7 184 1.7E-43 T 23-10-2018 TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 Pfam PF12838 4Fe-4S dicluster domain 303 340 3.6E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 303 314 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 Gene3D G3DSA:3.30.70.20 296 345 2.8E-8 T 23-10-2018 TAM4_1044 ccb47f67469a81e95929c546c443dd11 377 Gene3D G3DSA:3.40.50.620 1 206 8.1E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1307 f19615449a013a4f075bfe0b38c6bbc4 116 Pfam PF04266 ASCH domain 6 108 7.5E-17 T 23-10-2018 IPR007374 ASCH domain TAM4_1307 f19615449a013a4f075bfe0b38c6bbc4 116 SMART SM01022 6 109 4.4E-18 T 23-10-2018 IPR007374 ASCH domain TAM4_1307 f19615449a013a4f075bfe0b38c6bbc4 116 SUPERFAMILY SSF88697 2 109 1.49E-37 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_1307 f19615449a013a4f075bfe0b38c6bbc4 116 PIRSF PIRSF016134 2 111 4.2E-47 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TAM4_1307 f19615449a013a4f075bfe0b38c6bbc4 116 Gene3D G3DSA:2.30.130.30 2 109 8.4E-44 T 23-10-2018 TAM4_2429 1831d2b05d477d6537dc2df9c5e52a48 428 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 402 1.7E-34 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TAM4_2429 1831d2b05d477d6537dc2df9c5e52a48 428 Gene3D G3DSA:3.40.50.620 217 407 6.1E-35 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_2429 1831d2b05d477d6537dc2df9c5e52a48 428 SUPERFAMILY SSF52402 228 391 6.62E-32 T 23-10-2018 TAM4_934 2fe6e229034098e772716b6979c68b01 267 Pfam PF01255 Putative undecaprenyl diphosphate synthase 44 266 7.6E-83 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TAM4_934 2fe6e229034098e772716b6979c68b01 267 Gene3D G3DSA:3.40.1180.10 22 267 3.2E-103 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TAM4_934 2fe6e229034098e772716b6979c68b01 267 SUPERFAMILY SSF64005 34 262 8.24E-88 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TAM4_934 2fe6e229034098e772716b6979c68b01 267 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 37 266 3.7E-87 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TAM4_934 2fe6e229034098e772716b6979c68b01 267 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 37 267 40.196 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TAM4_934 2fe6e229034098e772716b6979c68b01 267 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 212 229 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Pfam PF08271 TFIIB zinc-binding 6 47 8.8E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 1.7E-57 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 45.657 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Gene3D G3DSA:1.10.472.170 6 202 3.0E-66 T 23-10-2018 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 SMART SM00385 214 295 9.9E-12 T 23-10-2018 IPR013763 Cyclin-like TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 SMART SM00385 120 201 2.5E-12 T 23-10-2018 IPR013763 Cyclin-like TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 SUPERFAMILY SSF57783 4 50 4.59E-17 T 23-10-2018 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Gene3D G3DSA:1.10.472.10 211 303 3.1E-27 T 23-10-2018 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 1.5E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 1.1E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 SUPERFAMILY SSF47954 211 302 1.02E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily TAM4_724 979ae047c638bf65f99858cecef1dc7e 303 SUPERFAMILY SSF47954 114 207 8.97E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 327 1.6E-93 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Gene3D G3DSA:3.40.50.11060 8 129 8.9E-34 T 23-10-2018 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 SUPERFAMILY SSF52540 186 361 1.84E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Pfam PF13167 GTP-binding GTPase N-terminal 18 100 2.8E-23 T 23-10-2018 IPR025121 GTPase HflX, N-terminal TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 1.3E-18 T 23-10-2018 IPR032305 GTP-binding protein, middle domain TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Hamap MF_00900 GTPase HflX [hflX]. 17 391 42.433 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 PIRSF PIRSF006809 1 416 1.2E-120 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Gene3D G3DSA:3.40.50.300 187 363 6.3E-43 T 23-10-2018 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 323 1.7E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 5.9E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 5.9E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 5.9E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1115 2430d730c1c081942936f3438cb7d1c6 428 Pfam PF01926 50S ribosome-binding GTPase 188 307 8.8E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 SMART SM00220 214 463 7.1E-57 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 Gene3D G3DSA:1.10.510.10 207 473 2.0E-64 T 23-10-2018 TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 324 336 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 SUPERFAMILY SSF56112 208 455 1.48E-68 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 220 242 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_2331 a8a77ea9da12fac980c2b0a0a54312c9 562 Pfam PF00069 Protein kinase domain 214 450 1.2E-46 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 8.9E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 Pfam PF00005 ABC transporter 28 181 6.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 2.6E-22 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 SUPERFAMILY SSF52540 4 264 2.18E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 SMART SM00382 36 231 2.5E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2472 2f1feda340bf4bd6021d443b0cc928e4 321 Gene3D G3DSA:3.40.50.300 1 320 6.1E-89 T 23-10-2018 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 Pfam PF01037 Lrp/AsnC ligand binding domain 71 139 6.6E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 Gene3D G3DSA:1.10.10.10 1 52 6.9E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 SUPERFAMILY SSF46785 2 62 3.49E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 SUPERFAMILY SSF54909 62 141 6.3E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 SMART SM00344 2 108 2.1E-48 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 4.7E-14 T 23-10-2018 TAM4_127 d47ae2e6e3f04375d7bbbfe493baf823 141 Gene3D G3DSA:3.30.70.920 65 141 6.8E-19 T 23-10-2018 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 PRINTS PR00762 Chloride channel signature 326 346 6.1E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 PRINTS PR00762 Chloride channel signature 379 398 6.1E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 PRINTS PR00762 Chloride channel signature 361 377 6.1E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 PRINTS PR00762 Chloride channel signature 81 98 6.1E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 PRINTS PR00762 Chloride channel signature 161 180 6.1E-18 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 Gene3D G3DSA:1.10.3080.10 5 432 2.5E-94 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 Gene3D G3DSA:3.10.580.10 437 564 6.5E-22 T 23-10-2018 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 SUPERFAMILY SSF54631 437 562 1.22E-24 T 23-10-2018 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 SMART SM00116 451 499 2.4E-7 T 23-10-2018 IPR000644 CBS domain TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 SMART SM00116 513 563 0.016 T 23-10-2018 IPR000644 CBS domain TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 Pfam PF00654 Voltage gated chloride channel 68 411 1.9E-86 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 SUPERFAMILY SSF81340 8 432 2.49E-100 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 Pfam PF00571 CBS domain 506 560 1.1E-7 T 23-10-2018 IPR000644 CBS domain TAM4_467 b5babb1ee1029c0e227ec74a768434c2 572 Pfam PF00571 CBS domain 444 496 2.2E-10 T 23-10-2018 IPR000644 CBS domain TAM4_1308 04c2314cf5dd5aa7a21ea19a9db63073 376 Gene3D G3DSA:1.20.1530.20 2 375 1.5E-86 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_1308 04c2314cf5dd5aa7a21ea19a9db63073 376 Pfam PF00999 Sodium/hydrogen exchanger family 10 370 4.7E-63 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_303 119267a727b44dc7acede01d521418d6 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 36.006 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 SUPERFAMILY SSF54919 6 152 1.3E-59 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 9.5E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 9.5E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 9.5E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 9.5E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 9.5E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TAM4_303 119267a727b44dc7acede01d521418d6 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 1.0E-56 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 SMART SM00562 6 146 5.1E-80 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_303 119267a727b44dc7acede01d521418d6 174 Gene3D G3DSA:3.30.70.141 1 159 4.3E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TAM4_1006 f7ee9758fd9fd7b5dd5bd9898c064ae9 164 SUPERFAMILY SSF46785 5 113 1.03E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1006 f7ee9758fd9fd7b5dd5bd9898c064ae9 164 SMART SM00418 24 90 0.005 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1006 f7ee9758fd9fd7b5dd5bd9898c064ae9 164 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 82 3.0E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TAM4_1006 f7ee9758fd9fd7b5dd5bd9898c064ae9 164 Gene3D G3DSA:1.10.10.10 3 81 2.4E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Gene3D G3DSA:3.90.740.10 170 337 5.0E-243 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 570 2.1E-140 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 793 28.998 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 2.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 2.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 2.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 2.3E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 SUPERFAMILY SSF50677 187 335 2.75E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 SUPERFAMILY SSF52374 3 579 7.72E-128 T 23-10-2018 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Gene3D G3DSA:1.10.730.10 2 750 5.0E-243 T 23-10-2018 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 SUPERFAMILY SSF47323 586 825 6.35E-62 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Pfam PF08264 Anticodon-binding domain of tRNA 614 762 6.1E-39 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 Gene3D G3DSA:3.40.50.620 22 535 5.0E-243 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_923 c882d8bd1c578a925243988bed199b8c 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_923 c882d8bd1c578a925243988bed199b8c 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 866 5.2E-272 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Gene3D G3DSA:3.40.50.2000 114 182 5.6E-11 T 23-10-2018 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 689 1.3E-255 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 1.4E-30 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Gene3D G3DSA:3.40.50.2000 404 714 8.5E-43 T 23-10-2018 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 SUPERFAMILY SSF53756 13 723 4.93E-207 T 23-10-2018 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 583 595 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Pfam PF00343 Carbohydrate phosphorylase 270 332 1.1E-4 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Pfam PF00343 Carbohydrate phosphorylase 124 174 3.1E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Pfam PF00343 Carbohydrate phosphorylase 347 609 6.0E-21 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 PIRSF PIRSF000460 1 764 2.5E-273 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TAM4_1498 9487cf17f1c2b637e7b72412fc3c214b 826 Gene3D G3DSA:3.40.50.2000 267 403 3.3E-8 T 23-10-2018 TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 Gene3D G3DSA:3.30.70.100 253 345 5.9E-29 T 23-10-2018 TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 SUPERFAMILY SSF82689 254 352 2.22E-33 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 Pfam PF00924 Mechanosensitive ion channel 138 341 1.3E-54 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 Gene3D G3DSA:2.30.30.60 198 251 2.8E-11 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 SUPERFAMILY SSF50182 183 251 6.21E-14 T 23-10-2018 IPR010920 LSM domain superfamily TAM4_912 8e4b42ba62c4e08928089934eb63a9fa 364 SUPERFAMILY SSF82861 99 181 9.94E-8 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TAM4_491 0898eaa15c0bc6c9af0d48c64aaa6723 102 SUPERFAMILY SSF54909 1 70 3.15E-5 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_2379 2955f19bacfe74338a3d8d660fe31779 72 SMART SM00966 6 47 6.2E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2379 2955f19bacfe74338a3d8d660fe31779 72 Gene3D G3DSA:2.10.260.10 2 51 2.6E-5 T 23-10-2018 TAM4_2379 2955f19bacfe74338a3d8d660fe31779 72 Pfam PF02381 MraZ protein, putative antitoxin-like 8 43 1.2E-4 T 23-10-2018 IPR020603 MraZ domain TAM4_2379 2955f19bacfe74338a3d8d660fe31779 72 SUPERFAMILY SSF89447 3 43 1.44E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_1263 bd5f119f58c93909d7ef735b6893e0e6 458 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 267 452 2.0E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1263 bd5f119f58c93909d7ef735b6893e0e6 458 Gene3D G3DSA:1.10.3720.10 239 456 1.5E-11 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1263 bd5f119f58c93909d7ef735b6893e0e6 458 SUPERFAMILY SSF161098 243 442 7.68E-11 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1798 2c7b7d7abc1cd65bc9aee9b3c110ce05 296 Pfam PF13732 Domain of unknown function (DUF4162) 207 291 3.0E-9 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 TAM4_1798 2c7b7d7abc1cd65bc9aee9b3c110ce05 296 Pfam PF00005 ABC transporter 19 153 9.6E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1798 2c7b7d7abc1cd65bc9aee9b3c110ce05 296 SUPERFAMILY SSF52540 3 214 1.38E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1798 2c7b7d7abc1cd65bc9aee9b3c110ce05 296 Gene3D G3DSA:3.40.50.300 1 225 3.4E-68 T 23-10-2018 TAM4_1798 2c7b7d7abc1cd65bc9aee9b3c110ce05 296 SMART SM00382 28 210 2.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 SUPERFAMILY SSF51161 243 409 5.6E-39 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 399 6.3E-6 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 1.5E-9 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 9.1E-157 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 Gene3D G3DSA:3.90.550.10 1 224 1.7E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 SUPERFAMILY SSF53448 2 312 2.93E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 Gene3D G3DSA:2.160.10.10 225 410 1.5E-59 T 23-10-2018 TAM4_697 be5b72c0e612c53d70285a79342c45d7 420 Pfam PF00483 Nucleotidyl transferase 2 231 4.6E-40 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 SUPERFAMILY SSF53671 2 306 1.44E-103 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 5.4E-132 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.676 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 302 6.0E-30 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 1.3E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 Gene3D G3DSA:3.40.50.1370 7 301 2.2E-125 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 1.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 1.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TAM4_188 df03da28d011f160c88d9a1172e11f10 311 Gene3D G3DSA:3.40.50.1370 135 292 2.2E-125 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 Pfam PF02926 THUMP domain 35 152 1.6E-29 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 SMART SM00981 64 153 6.3E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 173 346 3.2E-83 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 SUPERFAMILY SSF143437 11 151 5.93E-26 T 23-10-2018 TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 SUPERFAMILY SSF75217 191 340 4.92E-20 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_854 25c12f91255e2b785f2468d8c18a7a11 354 Gene3D G3DSA:3.30.2130.30 6 153 2.6E-23 T 23-10-2018 TAM4_1369 4636fce9c2a0afe0af8dfdb3a69c1a61 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 340 9.1E-36 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1369 4636fce9c2a0afe0af8dfdb3a69c1a61 347 SUPERFAMILY SSF161098 118 323 1.31E-14 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1369 4636fce9c2a0afe0af8dfdb3a69c1a61 347 Gene3D G3DSA:1.10.3720.10 112 336 5.3E-17 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 SUPERFAMILY SSF46767 90 169 3.01E-22 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 6.0E-30 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 5.4E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 2.9E-27 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 SUPERFAMILY SSF53155 1 88 2.67E-26 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 Gene3D G3DSA:1.10.10.10 89 174 5.1E-34 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 1.3E-30 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TAM4_2453 688e05743e1f777fb2d1b65b760781fd 174 Gene3D G3DSA:3.30.160.70 1 88 3.4E-34 T 23-10-2018 TAM4_513 50044ace667b76244fc6fda44d264569 98 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 85 1.2E-19 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 TAM4_513 50044ace667b76244fc6fda44d264569 98 SUPERFAMILY SSF55257 1 95 4.32E-24 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_513 50044ace667b76244fc6fda44d264569 98 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 20.192 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_513 50044ace667b76244fc6fda44d264569 98 Gene3D G3DSA:3.30.1360.10 1 94 7.2E-33 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_513 50044ace667b76244fc6fda44d264569 98 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 Gene3D G3DSA:3.50.50.60 136 257 7.3E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.4E-40 T 23-10-2018 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.4E-40 T 23-10-2018 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.4E-40 T 23-10-2018 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.4E-40 T 23-10-2018 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.4E-40 T 23-10-2018 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 2.1E-64 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 2.6E-60 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 Gene3D G3DSA:3.50.50.60 18 315 7.3E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 9.5E-123 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TAM4_1277 cad1e807bc99d196ef6f0ed292f580cd 330 SUPERFAMILY SSF51905 18 321 3.02E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1237 ebad4484250cfe62ca39619d50b9ee16 229 Gene3D G3DSA:1.10.3720.10 10 217 2.2E-52 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1237 ebad4484250cfe62ca39619d50b9ee16 229 SUPERFAMILY SSF161098 15 203 2.88E-44 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1237 ebad4484250cfe62ca39619d50b9ee16 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 213 4.8E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1237 ebad4484250cfe62ca39619d50b9ee16 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 111 2.4E-25 T 23-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 Gene3D G3DSA:1.10.10.10 2 55 6.0E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 8.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 8.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 8.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 4.5E-21 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 Gene3D G3DSA:3.30.70.920 57 151 2.2E-29 T 23-10-2018 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 4.5E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 SUPERFAMILY SSF54909 65 150 3.62E-23 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 SMART SM00344 5 111 2.9E-50 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_867 528eed310e5c2208d93a9d116c4a1b45 156 SUPERFAMILY SSF46785 4 64 4.42E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 PIRSF PIRSF000484 67 389 6.1E-48 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 PIRSF PIRSF000484 7 72 0.099 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 Gene3D G3DSA:3.90.1170.20 1 106 1.5E-45 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 Gene3D G3DSA:3.20.140.10 299 389 1.2E-6 T 23-10-2018 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 53 113 2.4E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 4.5E-28 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 Gene3D G3DSA:3.20.20.70 107 297 2.7E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 SUPERFAMILY SSF54675 2 115 1.18E-32 T 23-10-2018 TAM4_1083 c889f04b7dc8a52860a4349c7d1a58d3 390 SUPERFAMILY SSF51690 112 386 7.51E-77 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF55052 242 320 1.6E-11 T 23-10-2018 IPR035891 CheY-binding domain of CheA TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 5.2E-11 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 595 5.2E-11 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 552 5.2E-11 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 5.2E-11 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SMART SM00387 455 598 7.1E-23 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF47226 8 125 7.07E-19 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF55874 413 595 1.1E-36 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Gene3D G3DSA:1.20.120.160 6 135 1.4E-21 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Gene3D G3DSA:2.30.30.40 600 730 4.9E-10 T 23-10-2018 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF50341 600 735 5.75E-9 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SMART SM00073 5 103 3.5E-11 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Gene3D G3DSA:3.30.565.10 409 596 1.5E-44 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF47384 350 411 5.1E-5 T 23-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SUPERFAMILY SSF55052 148 229 4.97E-6 T 23-10-2018 IPR035891 CheY-binding domain of CheA TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 459 596 6.7E-17 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Pfam PF07194 P2 response regulator binding domain 149 229 1.8E-8 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Pfam PF07194 P2 response regulator binding domain 243 319 7.3E-12 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Gene3D G3DSA:2.40.50.180 621 686 4.9E-10 T 23-10-2018 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 SMART SM00260 590 735 0.001 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TAM4_1755 14c507a941ba08ae89992742ab779f2b 743 Pfam PF01627 Hpt domain 8 94 7.9E-14 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TAM4_2362 ed291a780dc4c465bc3c0ed5f204f24d 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 150 4.5E-55 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_2362 ed291a780dc4c465bc3c0ed5f204f24d 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 149 6.4E-51 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_2362 ed291a780dc4c465bc3c0ed5f204f24d 154 Gene3D G3DSA:3.40.50.960 3 153 3.7E-58 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_2362 ed291a780dc4c465bc3c0ed5f204f24d 154 SUPERFAMILY SSF52121 6 152 2.62E-57 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_2362 ed291a780dc4c465bc3c0ed5f204f24d 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 152 30.543 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_424 af8cb8dac17d434f0ead671715340cdf 397 Gene3D G3DSA:3.90.1150.10 24 389 1.1E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_424 af8cb8dac17d434f0ead671715340cdf 397 Gene3D G3DSA:3.40.640.10 53 294 1.1E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_424 af8cb8dac17d434f0ead671715340cdf 397 Pfam PF00155 Aminotransferase class I and II 31 386 4.6E-59 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_424 af8cb8dac17d434f0ead671715340cdf 397 SUPERFAMILY SSF53383 4 394 2.53E-105 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_424 af8cb8dac17d434f0ead671715340cdf 397 PIRSF PIRSF000517 4 396 2.7E-78 T 23-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 Gene3D G3DSA:3.40.50.720 1 234 2.7E-55 T 23-10-2018 TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 Pfam PF00106 short chain dehydrogenase 2 183 2.0E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.8E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.8E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 3.8E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.8E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_376 a3e70b119bc08b8dc67dc07439f511ed 237 SUPERFAMILY SSF51735 2 212 8.58E-52 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 Gene3D G3DSA:1.10.10.10 3 56 4.0E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 SMART SM00344 5 114 5.1E-47 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 6.9E-16 T 23-10-2018 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 SUPERFAMILY SSF46785 4 63 1.26E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 Pfam PF01037 Lrp/AsnC ligand binding domain 83 142 1.6E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 Gene3D G3DSA:3.30.70.920 59 150 1.9E-22 T 23-10-2018 TAM4_1259 81216cf514f368041c68b21d6f49d8f1 150 SUPERFAMILY SSF54909 65 143 8.45E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Pfam PF17214 KH domain 9 76 1.3E-27 T 23-10-2018 IPR033769 KH domain, archaeal TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 3.1E-300 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Pfam PF10996 Beta-Casp domain 433 556 4.7E-25 T 23-10-2018 IPR022712 Beta-Casp domain TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 351 6.0E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 SUPERFAMILY SSF56281 183 647 2.64E-135 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Gene3D G3DSA:3.40.50.10890 401 588 1.1E-167 T 23-10-2018 TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 SMART SM00849 198 417 4.9E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 SMART SM01027 433 557 3.8E-57 T 23-10-2018 IPR022712 Beta-Casp domain TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Gene3D G3DSA:3.60.15.10 191 627 1.1E-167 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 SUPERFAMILY SSF54814 97 135 6.1E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Gene3D G3DSA:3.30.300.230 18 176 1.4E-63 T 23-10-2018 TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 1.3E-17 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TAM4_1772 30b5b02b497a6b82fad1949648c64e89 648 Gene3D G3DSA:3.30.300.20 72 142 1.4E-63 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_503 167c135ba297a4e46ed3b8ee69e9f3d7 476 Pfam PF02272 DHHA1 domain 328 463 4.8E-20 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TAM4_503 167c135ba297a4e46ed3b8ee69e9f3d7 476 Gene3D G3DSA:3.10.310.30 336 469 8.1E-9 T 23-10-2018 TAM4_503 167c135ba297a4e46ed3b8ee69e9f3d7 476 SUPERFAMILY SSF64182 7 468 7.01E-63 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TAM4_503 167c135ba297a4e46ed3b8ee69e9f3d7 476 Gene3D G3DSA:3.90.1640.30 3 236 8.2E-18 T 23-10-2018 TAM4_795 000acff586283a503feed2efed50986c 289 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 1.6E-12 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TAM4_795 000acff586283a503feed2efed50986c 289 Gene3D G3DSA:3.40.50.150 62 287 1.3E-75 T 23-10-2018 TAM4_795 000acff586283a503feed2efed50986c 289 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TAM4_795 000acff586283a503feed2efed50986c 289 Gene3D G3DSA:2.30.140.10 6 60 8.9E-23 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TAM4_795 000acff586283a503feed2efed50986c 289 Pfam PF01564 Spermine/spermidine synthase domain 64 247 1.3E-48 T 23-10-2018 TAM4_795 000acff586283a503feed2efed50986c 289 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 286 35.667 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TAM4_795 000acff586283a503feed2efed50986c 289 SUPERFAMILY SSF53335 10 286 5.68E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_795 000acff586283a503feed2efed50986c 289 TIGRFAM TIGR00417 speE: spermidine synthase 10 280 8.7E-79 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TAM4_2167 18fcba733539f483f9a56cfe49253426 67 Gene3D G3DSA:3.30.70.20 1 33 1.1E-6 T 23-10-2018 TAM4_2167 18fcba733539f483f9a56cfe49253426 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_2167 18fcba733539f483f9a56cfe49253426 67 Gene3D G3DSA:3.30.70.20 34 67 3.0E-7 T 23-10-2018 TAM4_2167 18fcba733539f483f9a56cfe49253426 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_2167 18fcba733539f483f9a56cfe49253426 67 SUPERFAMILY SSF54862 3 64 4.65E-18 T 23-10-2018 TAM4_2167 18fcba733539f483f9a56cfe49253426 67 Pfam PF00037 4Fe-4S binding domain 38 58 3.8E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_2167 18fcba733539f483f9a56cfe49253426 67 Pfam PF00037 4Fe-4S binding domain 7 30 5.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1588 37c75d0914548293e2ba8f86513db4a0 224 Gene3D G3DSA:3.40.50.1000 8 137 1.9E-8 T 23-10-2018 IPR023214 HAD superfamily TAM4_1588 37c75d0914548293e2ba8f86513db4a0 224 SUPERFAMILY SSF56784 7 167 1.05E-12 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1588 37c75d0914548293e2ba8f86513db4a0 224 Gene3D G3DSA:1.10.150.520 18 87 1.9E-8 T 23-10-2018 TAM4_1588 37c75d0914548293e2ba8f86513db4a0 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 105 3.6E-5 T 23-10-2018 TAM4_922 34fdc8bd604aa452a9daadcd201fa9dc 222 Pfam PF08241 Methyltransferase domain 43 131 9.8E-28 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TAM4_922 34fdc8bd604aa452a9daadcd201fa9dc 222 Gene3D G3DSA:3.40.50.150 1 189 2.1E-55 T 23-10-2018 TAM4_922 34fdc8bd604aa452a9daadcd201fa9dc 222 SUPERFAMILY SSF53335 2 195 3.47E-52 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_263 86c2498d35a2f18304e02fa325aba929 209 SMART SM00322 38 104 2.2E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.763 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 4.1E-94 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 SUPERFAMILY SSF54821 86 186 3.01E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 Pfam PF07650 KH domain 17 88 5.0E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 Gene3D G3DSA:3.30.300.20 1 86 3.8E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_263 86c2498d35a2f18304e02fa325aba929 209 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 6.5E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 SUPERFAMILY SSF54814 7 93 8.63E-26 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_263 86c2498d35a2f18304e02fa325aba929 209 Gene3D G3DSA:3.30.1140.32 87 209 4.9E-41 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1273 1eabca59f3aaa2ccc725c280ee6aedee 84 Pfam PF01455 HupF/HypC family 3 63 2.3E-13 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1273 1eabca59f3aaa2ccc725c280ee6aedee 84 SUPERFAMILY SSF159127 3 65 1.83E-12 T 23-10-2018 IPR037254 HupF/HypC superfamily TAM4_1273 1eabca59f3aaa2ccc725c280ee6aedee 84 Gene3D G3DSA:2.40.50.970 1 70 8.4E-16 T 23-10-2018 IPR037254 HupF/HypC superfamily TAM4_173 ee3b7898183e630243a74c0c9ed7ab55 326 Gene3D G3DSA:3.40.190.10 32 314 2.1E-104 T 23-10-2018 TAM4_173 ee3b7898183e630243a74c0c9ed7ab55 326 SUPERFAMILY SSF53850 27 315 4.21E-80 T 23-10-2018 TAM4_173 ee3b7898183e630243a74c0c9ed7ab55 326 Gene3D G3DSA:3.40.190.10 114 251 2.1E-104 T 23-10-2018 TAM4_173 ee3b7898183e630243a74c0c9ed7ab55 326 Pfam PF16868 NMT1-like family 32 314 7.3E-91 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TAM4_173 ee3b7898183e630243a74c0c9ed7ab55 326 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 4 314 1.6E-105 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TAM4_1524 a36d981fcc7583320153b8a575927431 438 Pfam PF03008 Archaea bacterial proteins of unknown function 306 389 2.2E-12 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_1524 a36d981fcc7583320153b8a575927431 438 Gene3D G3DSA:3.40.50.300 1 168 8.3E-30 T 23-10-2018 TAM4_1524 a36d981fcc7583320153b8a575927431 438 SUPERFAMILY SSF46785 239 317 1.54E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1524 a36d981fcc7583320153b8a575927431 438 SUPERFAMILY SSF52540 2 240 3.2E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1524 a36d981fcc7583320153b8a575927431 438 Pfam PF09339 IclR helix-turn-helix domain 241 284 5.0E-8 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TAM4_1524 a36d981fcc7583320153b8a575927431 438 Pfam PF01637 ATPase domain predominantly from Archaea 3 198 5.9E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1524 a36d981fcc7583320153b8a575927431 438 Gene3D G3DSA:1.10.10.10 238 307 5.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 7.4E-32 T 23-10-2018 IPR001498 Impact, N-terminal TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 SUPERFAMILY SSF54980 136 195 1.37E-9 T 23-10-2018 IPR035647 EF-G domain III/V-like TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 9 194 1.5E-52 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 2.5E-13 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 Gene3D G3DSA:3.30.230.30 2 131 3.0E-47 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily TAM4_2019 3415a83e1c9e1df7c5220b8682d195e5 196 SUPERFAMILY SSF54211 3 130 3.72E-41 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_333 1b9d8a2648ca59463469600502f484ff 180 SUPERFAMILY SSF55811 50 175 8.67E-34 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TAM4_333 1b9d8a2648ca59463469600502f484ff 180 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TAM4_333 1b9d8a2648ca59463469600502f484ff 180 PRINTS PR00502 NUDIX hydrolase family signature 92 107 4.8E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TAM4_333 1b9d8a2648ca59463469600502f484ff 180 PRINTS PR00502 NUDIX hydrolase family signature 78 92 4.8E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TAM4_333 1b9d8a2648ca59463469600502f484ff 180 Pfam PF00293 NUDIX domain 56 172 7.6E-23 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TAM4_333 1b9d8a2648ca59463469600502f484ff 180 Gene3D G3DSA:3.90.79.10 47 177 2.2E-42 T 23-10-2018 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 103 119 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 126 141 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 145 161 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.7E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 Gene3D G3DSA:3.30.310.10 100 183 2.9E-35 T 23-10-2018 IPR012295 TBP domain superfamily TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 Gene3D G3DSA:3.30.310.10 16 99 2.0E-30 T 23-10-2018 IPR012295 TBP domain superfamily TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 101 182 7.0E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 88 2.9E-27 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 SUPERFAMILY SSF55945 97 183 4.08E-30 T 23-10-2018 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 130 179 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 SUPERFAMILY SSF55945 4 89 1.41E-27 T 23-10-2018 TAM4_545 e3c0f7ce1afb409519ee7c56bf175ffa 192 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 185 37.379 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_2476 f7d0035416934d0e35bbeb9cb1eca190 143 Pfam PF01850 PIN domain 2 116 2.0E-11 T 23-10-2018 IPR002716 PIN domain TAM4_2476 f7d0035416934d0e35bbeb9cb1eca190 143 SUPERFAMILY SSF88723 1 125 8.97E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2476 f7d0035416934d0e35bbeb9cb1eca190 143 Gene3D G3DSA:3.40.50.1010 1 124 1.9E-8 T 23-10-2018 TAM4_2476 f7d0035416934d0e35bbeb9cb1eca190 143 SMART SM00670 1 117 2.7E-4 T 23-10-2018 IPR002716 PIN domain TAM4_935 6427fb70402923030fbb27213d188c7f 293 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_935 6427fb70402923030fbb27213d188c7f 293 Gene3D G3DSA:3.30.70.20 59 116 1.6E-9 T 23-10-2018 TAM4_935 6427fb70402923030fbb27213d188c7f 293 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 267 1.8E-18 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_935 6427fb70402923030fbb27213d188c7f 293 Pfam PF12837 4Fe-4S binding domain 63 85 3.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_935 6427fb70402923030fbb27213d188c7f 293 SUPERFAMILY SSF52540 3 288 5.58E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_935 6427fb70402923030fbb27213d188c7f 293 SUPERFAMILY SSF54862 54 125 8.37E-19 T 23-10-2018 TAM4_1863 a38dd08fc090e37a78dfe7a5e67b85f4 138 Gene3D G3DSA:1.20.120.330 2 133 1.1E-39 T 23-10-2018 TAM4_1863 a38dd08fc090e37a78dfe7a5e67b85f4 138 SUPERFAMILY SSF81593 6 131 2.83E-43 T 23-10-2018 TAM4_1863 a38dd08fc090e37a78dfe7a5e67b85f4 138 Pfam PF05168 HEPN domain 8 129 7.0E-34 T 23-10-2018 IPR007842 HEPN domain TAM4_1863 a38dd08fc090e37a78dfe7a5e67b85f4 138 SMART SM00748 12 124 9.9E-44 T 23-10-2018 IPR007842 HEPN domain TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 SUPERFAMILY SSF52540 316 647 6.46E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 Gene3D G3DSA:3.40.50.300 522 663 4.9E-13 T 23-10-2018 TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 Pfam PF00271 Helicase conserved C-terminal domain 539 645 1.1E-8 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 Gene3D G3DSA:1.10.3210.30 27 231 4.9E-12 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 321 677 2.9E-65 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 Gene3D G3DSA:3.40.50.300 308 490 4.0E-11 T 23-10-2018 TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 SMART SM00490 563 646 2.6E-4 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 SMART SM00487 278 511 2.2E-7 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_2175 507b3f7df69f68a4b04101e1071ce7df 868 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 71 267 4.0E-14 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TAM4_1745 6fa9dc8ab2b30a8011a00a903ce24eeb 545 Gene3D G3DSA:3.40.50.300 264 541 1.8E-90 T 23-10-2018 TAM4_1745 6fa9dc8ab2b30a8011a00a903ce24eeb 545 Pfam PF00437 Type II/IV secretion system protein 166 428 3.5E-47 T 23-10-2018 IPR001482 Type II/IV secretion system protein TAM4_1745 6fa9dc8ab2b30a8011a00a903ce24eeb 545 Gene3D G3DSA:1.10.390.40 82 163 4.7E-56 T 23-10-2018 TAM4_1745 6fa9dc8ab2b30a8011a00a903ce24eeb 545 SUPERFAMILY SSF52540 146 528 5.31E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1745 6fa9dc8ab2b30a8011a00a903ce24eeb 545 Gene3D G3DSA:3.30.450.370 49 261 4.7E-56 T 23-10-2018 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 Gene3D G3DSA:3.60.20.10 1 192 5.6E-67 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 3 186 4.2E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 7 54 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 Pfam PF00227 Proteasome subunit 2 181 1.6E-54 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 SUPERFAMILY SSF56235 2 191 1.65E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 PRINTS PR00141 Proteasome component signature 142 153 1.4E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 PRINTS PR00141 Proteasome component signature 11 26 1.4E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 PRINTS PR00141 Proteasome component signature 167 178 1.4E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 PRINTS PR00141 Proteasome component signature 131 142 1.4E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_1486 4ae6687769314748be5cc8ff815b6460 194 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 194 35.347 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 SUPERFAMILY SSF53474 182 432 2.59E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 SUPERFAMILY SSF49452 73 162 4.25E-11 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 Gene3D G3DSA:3.40.50.1820 178 432 1.8E-66 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 Pfam PF00756 Putative esterase 194 429 4.4E-33 T 23-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 SMART SM01065 74 169 9.3E-7 T 23-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 TAM4_678 f08be4d44cd8384ed4bdf9805ecea7e8 433 Gene3D G3DSA:2.60.40.10 63 149 5.7E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_4 e8cbc173d6b1000708ba0cd34d0a1d3d 89 Gene3D G3DSA:2.30.30.210 1 89 2.2E-33 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 TAM4_4 e8cbc173d6b1000708ba0cd34d0a1d3d 89 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 8 84 19.506 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 TAM4_4 e8cbc173d6b1000708ba0cd34d0a1d3d 89 SUPERFAMILY SSF101744 2 88 3.49E-25 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 TAM4_4 e8cbc173d6b1000708ba0cd34d0a1d3d 89 Pfam PF01868 Domain of unknown function UPF0086 5 85 4.6E-20 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TAM4_4 e8cbc173d6b1000708ba0cd34d0a1d3d 89 SMART SM00538 1 89 6.0E-32 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 Gene3D G3DSA:3.40.50.150 2 194 2.9E-65 T 23-10-2018 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 Gene3D G3DSA:1.10.8.100 195 271 3.7E-9 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 SUPERFAMILY SSF53335 10 259 1.15E-63 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 260 3.7E-78 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 SMART SM00650 30 193 8.8E-78 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 264 45.958 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 Pfam PF00398 Ribosomal RNA adenine dimethylase 16 230 1.3E-52 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TAM4_2323 23c0ae4f45cb7bc63c806d66a6f15f85 283 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 438 3.3E-160 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 Pfam PF13537 Glutamine amidotransferase domain 72 199 5.9E-18 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 PIRSF PIRSF000485 1 441 2.2E-158 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 Pfam PF00156 Phosphoribosyl transferase domain 263 369 3.4E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 SUPERFAMILY SSF56235 5 240 8.58E-54 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 SUPERFAMILY SSF53271 233 439 2.36E-68 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 Gene3D G3DSA:3.40.50.2020 258 422 1.5E-144 T 23-10-2018 TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 Gene3D G3DSA:3.60.20.10 5 438 1.5E-144 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_621 0e9bb38df9ea70e9ac7eb7f855e93625 444 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 437 44.777 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TAM4_278 0af8702db6cd9ef68767651844842e0b 336 SUPERFAMILY SSF53335 87 335 4.96E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_278 0af8702db6cd9ef68767651844842e0b 336 Pfam PF02475 Met-10+ like-protein 89 266 1.3E-35 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TAM4_278 0af8702db6cd9ef68767651844842e0b 336 Gene3D G3DSA:3.30.300.110 64 146 7.2E-13 T 23-10-2018 TAM4_278 0af8702db6cd9ef68767651844842e0b 336 Gene3D G3DSA:3.40.50.150 150 335 4.5E-35 T 23-10-2018 TAM4_1501 23a2ffe541794019f39fd38c6dd6c11d 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 49 1.7E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1501 23a2ffe541794019f39fd38c6dd6c11d 76 Gene3D G3DSA:2.10.260.10 1 42 1.4E-16 T 23-10-2018 TAM4_1501 23a2ffe541794019f39fd38c6dd6c11d 76 SUPERFAMILY SSF89447 1 61 2.96E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_1501 23a2ffe541794019f39fd38c6dd6c11d 76 SMART SM00966 4 49 4.9E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1501 23a2ffe541794019f39fd38c6dd6c11d 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 3.8E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1856 23f4c72bd11c2bf69cc787dfb4ae2e79 161 Gene3D G3DSA:2.20.28.10 117 154 6.5E-20 T 23-10-2018 TAM4_1856 23f4c72bd11c2bf69cc787dfb4ae2e79 161 SUPERFAMILY SSF88723 18 112 1.92E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1856 23f4c72bd11c2bf69cc787dfb4ae2e79 161 Pfam PF17146 PIN domain of ribonuclease 3 85 2.8E-19 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 TAM4_1856 23f4c72bd11c2bf69cc787dfb4ae2e79 161 Gene3D G3DSA:3.40.50.1010 1 116 4.7E-43 T 23-10-2018 TAM4_74 52c0f704d9f181df2ac5d0dd1d37aab7 255 Pfam PF02598 Putative RNA methyltransferase 5 248 2.8E-49 T 23-10-2018 IPR003750 Putative RNA methyltransferase TAM4_74 52c0f704d9f181df2ac5d0dd1d37aab7 255 SUPERFAMILY SSF50249 91 156 2.23E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_74 52c0f704d9f181df2ac5d0dd1d37aab7 255 Gene3D G3DSA:2.40.50.140 91 156 2.0E-77 T 23-10-2018 TAM4_74 52c0f704d9f181df2ac5d0dd1d37aab7 255 SUPERFAMILY SSF75217 4 252 7.85E-47 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_74 52c0f704d9f181df2ac5d0dd1d37aab7 255 Gene3D G3DSA:3.40.1280.10 5 251 2.0E-77 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TAM4_1947 e3c99030b9b62fb3ca9cddb1546a7e4c 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 3.7E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_1947 e3c99030b9b62fb3ca9cddb1546a7e4c 247 Gene3D G3DSA:3.40.50.300 2 242 3.1E-47 T 23-10-2018 TAM4_1947 e3c99030b9b62fb3ca9cddb1546a7e4c 247 SUPERFAMILY SSF52540 3 244 7.84E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2353 5d7b35ff12df0936f07ac3868a813ffb 134 Gene3D G3DSA:1.10.10.10 77 134 9.8E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2353 5d7b35ff12df0936f07ac3868a813ffb 134 Pfam PF08279 HTH domain 96 129 8.1E-5 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 Pfam PF01467 Cytidylyltransferase-like 5 136 9.3E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 Gene3D G3DSA:3.40.50.620 1 178 6.5E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 SUPERFAMILY SSF52374 2 166 1.39E-36 T 23-10-2018 TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 168 3.8E-68 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 187 89.956 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TAM4_2357 6ab89248f87a78797af9caac4d40b389 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 61 4.5E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_117 d38e1282a228c819fd2b244057984ca1 80 Pfam PF01998 Protein of unknown function DUF131 33 72 2.6E-13 T 23-10-2018 IPR002849 Protein of unknown function DUF131 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Pfam PF03464 eRF1 domain 2 136 248 1.3E-16 T 23-10-2018 IPR005141 eRF1 domain 2 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Pfam PF03463 eRF1 domain 1 5 127 5.3E-29 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Gene3D G3DSA:2.30.30.870 1 129 3.1E-38 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Pfam PF03465 eRF1 domain 3 261 356 3.2E-25 T 23-10-2018 IPR005142 eRF1 domain 3 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 SUPERFAMILY SSF55315 251 356 1.53E-28 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 SUPERFAMILY SSF159065 1 128 4.45E-37 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Gene3D G3DSA:3.30.420.60 133 257 1.6E-35 T 23-10-2018 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.352 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 1.6E-113 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 SMART SM01194 1 129 6.6E-49 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 SUPERFAMILY SSF53137 131 259 4.1E-32 T 23-10-2018 TAM4_1860 32d2ac53a2216423aedb21827f01eec3 357 Gene3D G3DSA:3.30.1330.30 258 357 1.8E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_345 6c9253d39c99875235995727f4396d1f 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 5.7E-53 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TAM4_345 6c9253d39c99875235995727f4396d1f 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 6.4E-25 T 23-10-2018 TAM4_345 6c9253d39c99875235995727f4396d1f 133 SUPERFAMILY SSF54593 1 132 2.54E-34 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TAM4_345 6c9253d39c99875235995727f4396d1f 133 Gene3D G3DSA:3.10.180.10 1 131 6.7E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TAM4_826 efa625f3d8fdd85dab97bbe8e167dd00 455 SUPERFAMILY SSF111283 2 450 8.76E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_826 efa625f3d8fdd85dab97bbe8e167dd00 455 Gene3D G3DSA:3.30.2290.10 1 207 6.9E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_826 efa625f3d8fdd85dab97bbe8e167dd00 455 PIRSF PIRSF004919 1 455 7.8E-156 T 23-10-2018 IPR025502 TldD TAM4_826 efa625f3d8fdd85dab97bbe8e167dd00 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 3.3E-43 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_25 a809a8873beb22e8c469fd38235b4dc6 242 SUPERFAMILY SSF110849 14 241 2.35E-61 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TAM4_25 a809a8873beb22e8c469fd38235b4dc6 242 Gene3D G3DSA:3.90.1530.10 17 238 3.4E-84 T 23-10-2018 TAM4_25 a809a8873beb22e8c469fd38235b4dc6 242 Pfam PF02195 ParB-like nuclease domain 21 92 1.3E-8 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TAM4_25 a809a8873beb22e8c469fd38235b4dc6 242 SMART SM00470 19 114 7.0E-12 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TAM4_25 a809a8873beb22e8c469fd38235b4dc6 242 Gene3D G3DSA:3.30.1760.10 98 227 3.4E-84 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal TAM4_841 d2cd8eb5314276d12e2708cc817b08c5 346 Pfam PF01032 FecCD transport family 23 341 3.1E-93 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TAM4_841 d2cd8eb5314276d12e2708cc817b08c5 346 SUPERFAMILY SSF81345 5 341 6.41E-83 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_841 d2cd8eb5314276d12e2708cc817b08c5 346 Gene3D G3DSA:1.10.3470.10 9 345 2.1E-102 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 SUPERFAMILY SSF63882 7 182 1.44E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 1.6E-16 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 1.2E-46 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Gene3D G3DSA:3.90.105.10 27 181 2.4E-109 T 23-10-2018 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Gene3D G3DSA:3.40.980.10 19 314 2.4E-109 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Gene3D G3DSA:2.40.340.10 320 396 1.1E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Gene3D G3DSA:2.170.190.11 50 148 2.4E-109 T 23-10-2018 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 1.4E-18 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 SUPERFAMILY SSF63867 327 396 8.5E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 SUPERFAMILY SSF53218 181 322 1.2E-35 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_1767 b123cdec272d79cf5f9cd6d4b681f63a 396 SMART SM00852 186 317 8.8E-31 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1004 cd6af38d480a238ae034724b7b4d1b8c 99 Gene3D G3DSA:3.30.1860.10 1 97 1.2E-35 T 23-10-2018 TAM4_1004 cd6af38d480a238ae034724b7b4d1b8c 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 2.6E-33 T 23-10-2018 IPR007355 Protein of unknown function DUF424 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 PIRSF PIRSF001338 1 143 4.1E-59 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 SUPERFAMILY SSF52255 2 141 1.2E-52 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 SMART SM01001 1 142 7.9E-71 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 25.769 T 23-10-2018 IPR033747 Class I PurE TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 141 6.9E-55 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 Gene3D G3DSA:3.40.50.7700 2 143 4.8E-61 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TAM4_632 3eea2dab3c9b78c23301c63773c62900 143 Pfam PF00731 AIR carboxylase 2 142 4.1E-56 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:1.10.8.60 685 793 3.3E-35 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 554 683 1.8E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.8E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SMART SM01073 8 92 3.7E-45 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:3.40.50.300 179 349 4.3E-83 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SUPERFAMILY SSF52540 179 503 3.6E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:2.40.40.20 1 92 5.8E-38 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SMART SM00382 215 351 1.7E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SMART SM00382 550 686 8.9E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 793 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:3.40.50.300 509 683 5.9E-75 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Pfam PF09336 Vps4 C terminal oligomerisation domain 750 789 7.7E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:3.10.330.10 93 173 1.1E-7 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SMART SM01072 107 170 1.4E-17 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:1.10.8.60 429 506 1.2E-17 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 169 3.1E-13 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SUPERFAMILY SSF50692 2 90 1.18E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SUPERFAMILY SSF52540 512 791 1.62E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 ProSitePatterns PS00674 AAA-protein family signature. 654 672 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 SUPERFAMILY SSF54585 92 184 9.81E-21 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Gene3D G3DSA:1.10.8.60 350 413 4.3E-83 T 23-10-2018 TAM4_1739 a63ef58f5f1d07820ec4bbaf1846b30b 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 4.5E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 128 5.3E-22 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 SUPERFAMILY SSF47979 64 124 4.19E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 SUPERFAMILY SSF46785 4 63 7.49E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 SMART SM00529 25 124 1.4E-44 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 58 3.2E-18 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 Gene3D G3DSA:1.10.60.10 69 124 1.5E-21 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TAM4_711 dc9f7bdfd03026e0ce2b86fbb86a9bcc 141 Gene3D G3DSA:1.10.10.10 3 68 1.1E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 102 114 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 295 303 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 116 127 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 131 144 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 279 289 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Gene3D G3DSA:3.40.50.620 64 409 1.0E-119 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 6 569 39.975 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Gene3D G3DSA:2.40.240.100 410 570 6.4E-42 T 23-10-2018 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 2 571 2.4E-214 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Gene3D G3DSA:2.40.240.10 417 515 6.4E-42 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 SUPERFAMILY SSF50715 408 568 6.28E-31 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 SUPERFAMILY SSF52374 98 414 4.56E-91 T 23-10-2018 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 408 557 1.4E-29 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_1822 cf6ac08ef636390b6953f266d8aae0a4 571 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 98 404 5.5E-84 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 26 168 4.1E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 PRINTS PR00423 Cell division protein FtsZ signature 183 205 3.6E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 PRINTS PR00423 Cell division protein FtsZ signature 123 144 3.6E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 PRINTS PR00423 Cell division protein FtsZ signature 93 113 3.6E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 SMART SM00864 2 199 6.6E-34 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 Gene3D G3DSA:3.40.50.1440 1 363 1.1E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 SUPERFAMILY SSF52490 2 199 2.49E-41 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_765 3f2228757b860a0a46d865bb00c7cde0 365 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.62 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 TAM4_2005 9f2d3a6e1d7a0c5263048dd7e4925ff8 389 SUPERFAMILY SSF53383 2 385 3.99E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_2005 9f2d3a6e1d7a0c5263048dd7e4925ff8 389 Gene3D G3DSA:3.40.640.10 58 280 5.0E-153 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_2005 9f2d3a6e1d7a0c5263048dd7e4925ff8 389 Pfam PF00155 Aminotransferase class I and II 27 378 5.0E-77 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_2005 9f2d3a6e1d7a0c5263048dd7e4925ff8 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TAM4_2005 9f2d3a6e1d7a0c5263048dd7e4925ff8 389 Gene3D G3DSA:3.90.1150.10 28 378 5.0E-153 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 Gene3D G3DSA:1.10.1060.10 5 143 7.6E-44 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 15 464 2.3E-231 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 Gene3D G3DSA:3.50.50.60 258 399 2.3E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 19 131 5.0E-43 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 406 2.3E-16 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 314 2.3E-16 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 172 2.3E-16 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 440 2.3E-16 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 Gene3D G3DSA:3.40.50.720 147 257 5.4E-25 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 SUPERFAMILY SSF46548 7 159 6.28E-35 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 150 449 1.5E-41 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 418 440 1.0E-23 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 407 1.0E-23 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 170 1.0E-23 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 307 1.0E-23 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 252 1.0E-23 T 23-10-2018 TAM4_1090 36ba2ddeca078348d669fcce67d9e751 471 SUPERFAMILY SSF51971 150 399 1.41E-70 T 23-10-2018 TAM4_1296 6c7b178ad1d81cb03a44b3bdcefc6a58 242 SUPERFAMILY SSF52540 2 237 2.28E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1296 6c7b178ad1d81cb03a44b3bdcefc6a58 242 Gene3D G3DSA:3.40.50.300 1 240 6.4E-41 T 23-10-2018 TAM4_1296 6c7b178ad1d81cb03a44b3bdcefc6a58 242 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 152 4.7E-12 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_1296 6c7b178ad1d81cb03a44b3bdcefc6a58 242 PIRSF PIRSF005647 1 240 2.2E-64 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type TAM4_1720 46540043de0079ac4cda0527c92c35c5 208 Pfam PF01850 PIN domain 4 171 5.9E-8 T 23-10-2018 IPR002716 PIN domain TAM4_1720 46540043de0079ac4cda0527c92c35c5 208 SUPERFAMILY SSF88723 3 174 6.45E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_473 f068481dbdc693636df5baff77708f46 315 Pfam PF01145 SPFH domain / Band 7 family 25 205 2.9E-42 T 23-10-2018 IPR001107 Band 7 domain TAM4_473 f068481dbdc693636df5baff77708f46 315 SUPERFAMILY SSF117892 52 185 9.94E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 28 50 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 75 96 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 173 194 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 130 153 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 110 127 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 PRINTS PR00721 Stomatin signature 154 172 2.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_473 f068481dbdc693636df5baff77708f46 315 SMART SM00244 21 178 2.5E-73 T 23-10-2018 IPR001107 Band 7 domain TAM4_473 f068481dbdc693636df5baff77708f46 315 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site TAM4_473 f068481dbdc693636df5baff77708f46 315 Gene3D G3DSA:3.30.479.30 49 180 1.0E-51 T 23-10-2018 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 Gene3D G3DSA:3.60.20.10 2 199 1.2E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 35.165 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 SUPERFAMILY SSF56235 3 193 3.26E-60 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 PRINTS PR00141 Proteasome component signature 146 157 5.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 PRINTS PR00141 Proteasome component signature 135 146 5.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 PRINTS PR00141 Proteasome component signature 15 30 5.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 2.7E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TAM4_221 7d828c4dc31eaa43d7c6db15d4aacc41 200 Pfam PF00227 Proteasome subunit 5 186 1.0E-53 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_10 6704799a5567d7c7f5a7d917f05f3606 103 SUPERFAMILY SSF50447 27 102 7.51E-9 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_10 6704799a5567d7c7f5a7d917f05f3606 103 Gene3D G3DSA:2.40.30.10 17 103 8.8E-19 T 23-10-2018 TAM4_10 6704799a5567d7c7f5a7d917f05f3606 103 Pfam PF14578 Elongation factor Tu domain 4 22 99 1.1E-16 T 23-10-2018 IPR029459 Elongation factor Tu-type domain TAM4_285 5b9568437eef66ff632045b5f48f7b86 590 Pfam PF13353 4Fe-4S single cluster domain 143 223 1.7E-6 T 23-10-2018 TAM4_285 5b9568437eef66ff632045b5f48f7b86 590 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 145 156 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_285 5b9568437eef66ff632045b5f48f7b86 590 SUPERFAMILY SSF102114 128 396 9.81E-43 T 23-10-2018 TAM4_285 5b9568437eef66ff632045b5f48f7b86 590 Gene3D G3DSA:3.20.20.70 128 401 9.8E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_285 5b9568437eef66ff632045b5f48f7b86 590 Pfam PF04055 Radical SAM superfamily 143 302 9.8E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 SUPERFAMILY SSF54575 6 77 4.84E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 Pfam PF01198 Ribosomal protein L31e 12 73 6.3E-10 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 89 22.933 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 9 57 1.0E-13 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 ProSitePatterns PS01144 Ribosomal protein L31e signature. 47 61 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 SMART SM01380 7 83 1.4E-20 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1591 8945fc5d2e2b261a87f7712b00e1e1e0 89 Gene3D G3DSA:3.10.440.10 2 89 3.9E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1321 722e27d623228a99aa52888babd0fd40 648 SUPERFAMILY SSF50249 570 640 5.65E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1321 722e27d623228a99aa52888babd0fd40 648 SUPERFAMILY SSF50249 372 447 2.23E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Pfam PF00037 4Fe-4S binding domain 540 563 9.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Pfam PF00037 4Fe-4S binding domain 571 593 2.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SMART SM00928 439 484 9.8E-24 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Gene3D G3DSA:3.30.70.20 543 592 8.7E-13 T 23-10-2018 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Gene3D G3DSA:3.10.20.600 342 436 1.4E-32 T 23-10-2018 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 8.2E-33 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Pfam PF10531 SLBB domain 353 401 9.1E-10 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SUPERFAMILY SSF140490 435 531 8.5E-37 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Gene3D G3DSA:3.40.30.10 5 97 6.1E-21 T 23-10-2018 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Gene3D G3DSA:1.20.1440.230 437 538 4.9E-35 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SUPERFAMILY SSF142019 112 350 9.02E-97 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SUPERFAMILY SSF54862 540 596 3.12E-15 T 23-10-2018 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Gene3D G3DSA:3.40.50.11540 163 341 2.7E-84 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SUPERFAMILY SSF142984 351 434 3.14E-25 T 23-10-2018 TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 SUPERFAMILY SSF52833 7 98 7.6E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_363 e79d3c74010255f44d98cdd47943ffb3 599 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 329 4.4E-51 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 Gene3D G3DSA:1.10.10.10 234 319 7.4E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 SUPERFAMILY SSF46785 240 395 2.9E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 Pfam PF01637 ATPase domain predominantly from Archaea 5 202 2.0E-29 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 Pfam PF09339 IclR helix-turn-helix domain 241 281 1.1E-6 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 Pfam PF03008 Archaea bacterial proteins of unknown function 306 404 1.5E-30 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 SUPERFAMILY SSF52540 3 238 1.46E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1656 22d96a095ac1b608898ebfa6794a2207 452 Gene3D G3DSA:3.40.50.300 2 168 2.4E-29 T 23-10-2018 TAM4_1210 555a71632e11671f4678fe7e5f23e957 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TAM4_1210 555a71632e11671f4678fe7e5f23e957 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 1.0E-186 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TAM4_1210 555a71632e11671f4678fe7e5f23e957 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 62.182 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TAM4_1210 555a71632e11671f4678fe7e5f23e957 375 SUPERFAMILY SSF111249 6 372 3.79E-178 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TAM4_1210 555a71632e11671f4678fe7e5f23e957 375 PIRSF PIRSF015647 5 375 2.8E-192 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 412 483 2.2E-16 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Gene3D G3DSA:3.30.930.10 12 283 4.6E-87 T 23-10-2018 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 SUPERFAMILY SSF64586 406 483 6.67E-22 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 SUPERFAMILY SSF55681 11 277 5.94E-78 T 23-10-2018 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Hamap MF_01571 Proline--tRNA ligase [proS]. 6 483 41.612 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 SUPERFAMILY SSF52954 279 403 7.4E-38 T 23-10-2018 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Pfam PF03129 Anticodon binding domain 290 384 2.8E-23 T 23-10-2018 IPR004154 Anticodon-binding TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Gene3D G3DSA:3.40.50.800 284 402 4.2E-37 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 273 1.7E-22 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 SMART SM00946 411 483 8.1E-26 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 483 5.7E-185 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_576 9ddc29ee4af0d2a8645ae4308760649b 483 Gene3D G3DSA:3.30.110.30 405 482 6.1E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TAM4_179 59056d2e1cd36387cdee1ced75b50714 307 SUPERFAMILY SSF53448 4 226 1.86E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_179 59056d2e1cd36387cdee1ced75b50714 307 Gene3D G3DSA:3.90.550.10 1 251 1.9E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_179 59056d2e1cd36387cdee1ced75b50714 307 Pfam PF00535 Glycosyl transferase family 2 7 136 1.2E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_716 1352e087ae51533676ce06347c9c3242 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 226 1.8E-74 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TAM4_716 1352e087ae51533676ce06347c9c3242 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 167 175 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_716 1352e087ae51533676ce06347c9c3242 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 229 31.883 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_716 1352e087ae51533676ce06347c9c3242 235 Gene3D G3DSA:3.30.470.20 80 215 3.4E-95 T 23-10-2018 TAM4_716 1352e087ae51533676ce06347c9c3242 235 Gene3D G3DSA:3.30.200.20 17 227 3.4E-95 T 23-10-2018 TAM4_716 1352e087ae51533676ce06347c9c3242 235 Pfam PF01259 SAICAR synthetase 3 223 1.0E-66 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_716 1352e087ae51533676ce06347c9c3242 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_716 1352e087ae51533676ce06347c9c3242 235 SUPERFAMILY SSF56104 4 230 3.17E-81 T 23-10-2018 TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 Gene3D G3DSA:3.40.50.300 1 182 7.4E-38 T 23-10-2018 TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 174 2.9E-19 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 Pfam PF01926 50S ribosome-binding GTPase 3 136 9.3E-23 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 SUPERFAMILY SSF52540 2 182 7.44E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 3.9E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1664 5d3d2060a2cb7163b7bd74ce60885f2a 188 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 3.9E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 Gene3D G3DSA:1.10.10.10 2 55 3.1E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 SUPERFAMILY SSF46785 4 61 5.54E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 SUPERFAMILY SSF54909 66 125 6.84E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.0E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 Gene3D G3DSA:3.30.70.920 56 137 2.4E-10 T 23-10-2018 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 Pfam PF01037 Lrp/AsnC ligand binding domain 79 124 7.8E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 3.7E-14 T 23-10-2018 TAM4_421 e9ab79ed8fc6aab9196786932ea33a10 166 SMART SM00344 4 112 8.1E-31 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 Gene3D G3DSA:3.40.50.720 14 139 1.5E-16 T 23-10-2018 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 Gene3D G3DSA:3.50.50.60 140 279 6.3E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 3.0E-16 T 23-10-2018 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 3.0E-16 T 23-10-2018 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 3.0E-16 T 23-10-2018 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 SUPERFAMILY SSF51971 17 282 5.89E-54 T 23-10-2018 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 335 2.4E-35 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 Gene3D G3DSA:3.50.50.60 280 349 4.1E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 1.3E-15 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 1.3E-15 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_594 dfea116d8a8ccd5afa27a65f2c1d453d 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 310 328 1.3E-15 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 7.7E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 SUPERFAMILY SSF51735 182 417 9.29E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 1.3E-31 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 1.3E-31 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 1.3E-31 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 1.3E-31 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 Gene3D G3DSA:3.40.50.720 182 418 2.0E-99 T 23-10-2018 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 PIRSF PIRSF000185 1 418 7.4E-176 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 5.4E-79 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 SMART SM00839 184 415 1.0E-103 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 Gene3D G3DSA:3.40.50.10860 36 181 6.9E-68 T 23-10-2018 TAM4_369 945e6a680236d31e2b3916e60aa4dbf5 419 SUPERFAMILY SSF53223 4 184 2.65E-69 T 23-10-2018 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 6.9E-28 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 3.2E-82 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 Pfam PF01380 SIS domain 246 350 5.5E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 Gene3D G3DSA:3.20.20.70 1 206 1.2E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 SUPERFAMILY SSF53697 215 404 1.96E-39 T 23-10-2018 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 221 406 1.4E-74 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 SUPERFAMILY SSF51366 2 213 1.52E-45 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 SMART SM00934 2 203 2.1E-45 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_82 3696037fcb6b40d185da852ed02bb303 406 Gene3D G3DSA:3.40.50.10490 213 406 6.6E-58 T 23-10-2018 TAM4_1786 fc0b50013b85ff4929e4b5f53e89f0bd 441 Pfam PF13347 MFS/sugar transport protein 42 392 2.9E-16 T 23-10-2018 TAM4_1786 fc0b50013b85ff4929e4b5f53e89f0bd 441 Gene3D G3DSA:1.20.1250.20 5 213 1.6E-13 T 23-10-2018 TAM4_1786 fc0b50013b85ff4929e4b5f53e89f0bd 441 Gene3D G3DSA:1.20.1250.20 231 427 1.3E-20 T 23-10-2018 TAM4_1786 fc0b50013b85ff4929e4b5f53e89f0bd 441 SUPERFAMILY SSF103473 7 420 1.13E-35 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 452 515 6.3E-13 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 274 442 1.8E-47 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 22 140 2.3E-28 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 195 206 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Gene3D G3DSA:1.10.645.20 159 516 6.9E-125 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 140 5.0E-11 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 SUPERFAMILY SSF143243 16 173 1.18E-39 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 SUPERFAMILY SSF56762 168 516 4.45E-115 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Pfam PF00374 Nickel-dependent hydrogenase 197 267 9.6E-16 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TAM4_1098 9e70d6bf082e232a99d5bea477e94018 545 Gene3D G3DSA:3.30.460.80 4 118 3.2E-17 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 380 7.9E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 3.8E-62 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 Gene3D G3DSA:2.70.98.10 386 652 5.1E-87 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 647 5.1E-76 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 SUPERFAMILY SSF74650 387 651 7.85E-98 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 SUPERFAMILY SSF88688 309 381 5.49E-37 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 7.0E-29 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 SUPERFAMILY SSF88713 3 307 2.19E-68 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_15 f4e52aac72bf4075666122b26fbd3615 652 Gene3D G3DSA:3.20.110.20 1 379 3.3E-173 T 23-10-2018 TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 3.1E-201 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 Pfam PF00155 Aminotransferase class I and II 40 383 4.4E-70 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 Gene3D G3DSA:3.40.640.10 55 291 1.5E-139 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 Gene3D G3DSA:3.90.1150.10 35 385 1.5E-139 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_365 9d927715a5735e4e5aea2d6085ee5e66 395 SUPERFAMILY SSF53383 4 391 3.19E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Gene3D G3DSA:3.30.420.350 95 305 7.4E-66 T 23-10-2018 TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Gene3D G3DSA:3.90.870.20 330 533 4.2E-73 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Gene3D G3DSA:3.30.420.40 9 312 7.4E-66 T 23-10-2018 TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 7.1E-40 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Pfam PF02543 Carbamoyltransferase N-terminus 2 69 2.9E-9 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 SUPERFAMILY SSF53067 11 315 4.27E-13 T 23-10-2018 TAM4_990 3cf4839f4b31fcf254b6f6e7eb690326 535 Pfam PF16861 Carbamoyltransferase C-terminus 364 532 4.1E-62 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal TAM4_532 52f2ae864c10d941fcc311bf84bfd2c9 467 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 437 1.9E-69 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_532 52f2ae864c10d941fcc311bf84bfd2c9 467 Pfam PF01554 MatE 26 185 2.9E-33 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_532 52f2ae864c10d941fcc311bf84bfd2c9 467 Pfam PF01554 MatE 288 424 8.3E-24 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_532 52f2ae864c10d941fcc311bf84bfd2c9 467 PIRSF PIRSF006603 1 467 7.7E-139 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 Gene3D G3DSA:1.10.1510.30 171 256 6.7E-116 T 23-10-2018 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 SUPERFAMILY SSF55120 8 413 6.62E-93 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 PIRSF PIRSF037016 388 415 0.018 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 PIRSF PIRSF037016 34 390 1.1E-61 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 Gene3D G3DSA:3.30.70.3160 43 125 6.7E-116 T 23-10-2018 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 414 3.1E-84 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 Gene3D G3DSA:3.30.2350.20 126 410 6.7E-116 T 23-10-2018 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 415 29.441 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_112 e1b3d0b5015d5cdbd3bccb5c957ab1be 415 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 411 3.0E-132 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 Gene3D G3DSA:3.40.50.261 142 306 2.5E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 SUPERFAMILY SSF52210 143 305 2.22E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 Gene3D G3DSA:3.40.50.261 310 473 7.2E-53 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 SMART SM00881 12 111 1.2E-35 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 Gene3D G3DSA:3.40.50.720 8 140 4.9E-43 T 23-10-2018 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 SUPERFAMILY SSF52210 311 469 3.14E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 1.2E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 SUPERFAMILY SSF51735 9 141 8.76E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_531 53c10dee7446c8849cfb4d8112e70c74 473 Pfam PF13380 CoA binding domain 16 145 4.2E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_328 09a2e599422940d840727681e72949e8 299 SUPERFAMILY SSF47413 13 64 1.49E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_328 09a2e599422940d840727681e72949e8 299 Gene3D G3DSA:3.40.225.10 123 296 2.2E-44 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TAM4_328 09a2e599422940d840727681e72949e8 299 Pfam PF10120 Thiamine-phosphate synthase 132 288 2.4E-46 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TAM4_328 09a2e599422940d840727681e72949e8 299 SUPERFAMILY SSF53639 127 291 2.51E-48 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 Gene3D G3DSA:3.30.930.10 3 189 5.4E-54 T 23-10-2018 TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 Pfam PF02237 Biotin protein ligase C terminal domain 192 238 1.7E-11 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 Pfam PF03099 Biotin/lipoate A/B protein ligase family 26 123 1.5E-16 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 8 238 1.3E-57 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 Gene3D G3DSA:2.30.30.100 192 239 7.2E-14 T 23-10-2018 TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 SUPERFAMILY SSF50037 192 238 1.92E-6 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TAM4_1587 d18614af0e818945f92bfc2c8a449450 240 SUPERFAMILY SSF55681 5 186 3.54E-51 T 23-10-2018 TAM4_389 9cc1ed665b9ff85deb0d52db51a55cd0 435 Gene3D G3DSA:3.30.2290.10 1 212 4.5E-19 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_389 9cc1ed665b9ff85deb0d52db51a55cd0 435 Pfam PF01523 Putative modulator of DNA gyrase 17 310 9.7E-44 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_389 9cc1ed665b9ff85deb0d52db51a55cd0 435 SUPERFAMILY SSF111283 2 429 4.05E-79 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_435 d417d45f382c4d16d5a7a5bec6fcce85 333 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 9.9E-101 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TAM4_435 d417d45f382c4d16d5a7a5bec6fcce85 333 Hamap MF_01086 UPF0284 protein . 1 333 138.236 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TAM4_435 d417d45f382c4d16d5a7a5bec6fcce85 333 Gene3D G3DSA:3.40.50.10210 1 333 8.2E-128 T 23-10-2018 TAM4_435 d417d45f382c4d16d5a7a5bec6fcce85 333 SUPERFAMILY SSF52733 18 327 1.24E-42 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 Gene3D G3DSA:3.50.50.60 107 423 1.2E-120 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_348 25c9feb6cd2009449913c784368cfd20 445 Gene3D G3DSA:3.50.50.60 5 333 1.2E-120 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_348 25c9feb6cd2009449913c784368cfd20 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 424 4.1E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 297 1.3E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 2.7E-26 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 2.7E-26 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.7E-26 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.7E-26 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.7E-26 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 SUPERFAMILY SSF55424 318 441 2.58E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 SUPERFAMILY SSF51905 1 306 1.62E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 5.7E-21 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 5.7E-21 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 5.7E-21 T 23-10-2018 TAM4_348 25c9feb6cd2009449913c784368cfd20 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 5.7E-21 T 23-10-2018 TAM4_40 7417866b5dfdd9f3e5df442d73db817a 453 Gene3D G3DSA:3.30.2290.10 1 188 8.4E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_40 7417866b5dfdd9f3e5df442d73db817a 453 SUPERFAMILY SSF111283 4 448 1.7E-106 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_40 7417866b5dfdd9f3e5df442d73db817a 453 Pfam PF01523 Putative modulator of DNA gyrase 20 308 1.7E-66 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_40 7417866b5dfdd9f3e5df442d73db817a 453 PIRSF PIRSF004919 1 453 2.9E-156 T 23-10-2018 IPR025502 TldD TAM4_2375 ace494e95642bfb1c71b8aec54c9ffc8 130 PIRSF PIRSF014543 1 121 5.7E-31 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TAM4_2375 ace494e95642bfb1c71b8aec54c9ffc8 130 Pfam PF12646 Domain of unknown function (DUF3783) 55 110 3.8E-13 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TAM4_734 663decb3a6875a352aa98a7f7aa4ba84 227 SUPERFAMILY SSF56300 17 126 3.07E-11 T 23-10-2018 TAM4_734 663decb3a6875a352aa98a7f7aa4ba84 227 Gene3D G3DSA:3.60.21.10 13 156 2.1E-6 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_734 663decb3a6875a352aa98a7f7aa4ba84 227 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 6 221 2.0E-44 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like TAM4_734 663decb3a6875a352aa98a7f7aa4ba84 227 PIRSF PIRSF000887 1 224 2.5E-60 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TAM4_925 7ee73bbbf302434abce50114e901328e 151 SMART SM00344 7 113 3.1E-29 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_925 7ee73bbbf302434abce50114e901328e 151 Gene3D G3DSA:1.10.10.10 1 58 1.7E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_925 7ee73bbbf302434abce50114e901328e 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_925 7ee73bbbf302434abce50114e901328e 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_925 7ee73bbbf302434abce50114e901328e 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_925 7ee73bbbf302434abce50114e901328e 151 SUPERFAMILY SSF46785 6 67 1.86E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_925 7ee73bbbf302434abce50114e901328e 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 54 8.2E-15 T 23-10-2018 TAM4_925 7ee73bbbf302434abce50114e901328e 151 Gene3D G3DSA:3.30.70.920 59 151 8.1E-26 T 23-10-2018 TAM4_706 cf00a0ab926c933c119df06ee02c8981 331 Gene3D G3DSA:3.30.70.2580 1 58 4.3E-7 T 23-10-2018 TAM4_706 cf00a0ab926c933c119df06ee02c8981 331 Gene3D G3DSA:3.40.50.150 143 331 7.1E-57 T 23-10-2018 TAM4_706 cf00a0ab926c933c119df06ee02c8981 331 Gene3D G3DSA:3.30.300.110 59 142 1.1E-27 T 23-10-2018 TAM4_706 cf00a0ab926c933c119df06ee02c8981 331 SUPERFAMILY SSF53335 72 329 8.59E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_706 cf00a0ab926c933c119df06ee02c8981 331 Pfam PF02475 Met-10+ like-protein 82 277 2.8E-72 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TAM4_186 1f81100ce6fb5f8adcec0d1c129129cb 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 1.7E-68 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TAM4_186 1f81100ce6fb5f8adcec0d1c129129cb 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 5.0E-91 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TAM4_186 1f81100ce6fb5f8adcec0d1c129129cb 188 PIRSF PIRSF006503 1 188 6.1E-84 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TAM4_186 1f81100ce6fb5f8adcec0d1c129129cb 188 Gene3D G3DSA:3.30.930.10 1 188 4.6E-72 T 23-10-2018 TAM4_186 1f81100ce6fb5f8adcec0d1c129129cb 188 SUPERFAMILY SSF55681 3 186 9.74E-72 T 23-10-2018 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 Gene3D G3DSA:1.10.3270.10 1 72 5.9E-7 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 SUPERFAMILY SSF56542 4 396 1.44E-92 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 406 8.4E-171 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 274 300 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 93 113 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 326 347 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 183 201 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 223 248 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 62 83 2.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 338 345 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 185 199 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 30 406 5.9E-140 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 Gene3D G3DSA:3.90.770.10 73 393 2.4E-132 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 Gene3D G3DSA:3.30.70.420 127 242 2.4E-132 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_2137 a4aaf4749d96c07ef91454a6f09d89cc 406 SUPERFAMILY SSF55035 127 242 1.44E-39 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 SMART SM00746 7 45 6.6E-12 T 23-10-2018 IPR011017 TRASH domain TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 Gene3D G3DSA:2.30.170.20 2 66 2.6E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 Pfam PF01246 Ribosomal protein L24e 3 60 2.7E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 SUPERFAMILY SSF57716 6 56 6.7E-21 T 23-10-2018 TAM4_52 ef48bcd2a6a5a1c9760b5efa8b93e240 68 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.306 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_158 57a4572323227c533ef66ffd26352a4f 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 280 1.3E-23 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TAM4_158 57a4572323227c533ef66ffd26352a4f 286 Gene3D G3DSA:3.30.70.1350 203 282 4.9E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TAM4_158 57a4572323227c533ef66ffd26352a4f 286 SUPERFAMILY SSF161111 4 202 1.83E-58 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TAM4_158 57a4572323227c533ef66ffd26352a4f 286 SUPERFAMILY SSF160240 205 280 2.09E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TAM4_158 57a4572323227c533ef66ffd26352a4f 286 Gene3D G3DSA:1.20.1510.10 4 200 5.8E-65 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TAM4_158 57a4572323227c533ef66ffd26352a4f 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 1.2E-85 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TAM4_158 57a4572323227c533ef66ffd26352a4f 286 Pfam PF01545 Cation efflux family 8 200 1.0E-48 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TAM4_118 b66fb20f198ca834971bc39a03b75472 239 Gene3D G3DSA:3.40.50.2020 63 239 5.0E-38 T 23-10-2018 TAM4_118 b66fb20f198ca834971bc39a03b75472 239 SUPERFAMILY SSF47413 20 63 4.64E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_118 b66fb20f198ca834971bc39a03b75472 239 SUPERFAMILY SSF53271 71 238 2.1E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_118 b66fb20f198ca834971bc39a03b75472 239 Pfam PF00156 Phosphoribosyl transferase domain 102 221 3.3E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_118 b66fb20f198ca834971bc39a03b75472 239 SMART SM00530 16 68 0.0076 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_118 b66fb20f198ca834971bc39a03b75472 239 Pfam PF01381 Helix-turn-helix 17 62 2.3E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 SUPERFAMILY SSF52402 177 336 3.97E-50 T 23-10-2018 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 368 1.6E-65 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 SUPERFAMILY SSF143437 1 175 6.28E-49 T 23-10-2018 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 380 127.655 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Gene3D G3DSA:3.30.70.1510 1 83 1.2E-33 T 23-10-2018 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Pfam PF02926 THUMP domain 28 167 1.1E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Gene3D G3DSA:3.40.50.620 177 375 8.3E-65 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 365 3.9E-106 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 Gene3D G3DSA:3.30.2300.10 84 165 8.6E-31 T 23-10-2018 TAM4_1726 0e17aa4e399ebb76b95c0807efe8b6dd 380 SMART SM00981 73 167 1.7E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_824 2e8da2219e692ce8feec42a66207db21 442 PIRSF PIRSF005353 1 439 4.4E-165 T 23-10-2018 IPR026033 Purine permease PbuG-like TAM4_824 2e8da2219e692ce8feec42a66207db21 442 Pfam PF00860 Permease family 20 397 3.4E-43 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TAM4_506 92126895ed8756854984d059728fe795 631 SUPERFAMILY SSF54862 569 623 1.1E-13 T 23-10-2018 TAM4_506 92126895ed8756854984d059728fe795 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_506 92126895ed8756854984d059728fe795 631 SMART SM00359 133 207 4.1E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_506 92126895ed8756854984d059728fe795 631 SUPERFAMILY SSF52402 223 417 1.1E-47 T 23-10-2018 TAM4_506 92126895ed8756854984d059728fe795 631 SUPERFAMILY SSF88697 133 204 4.64E-18 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_506 92126895ed8756854984d059728fe795 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_506 92126895ed8756854984d059728fe795 631 Gene3D G3DSA:2.30.130.10 130 207 4.4E-14 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_506 92126895ed8756854984d059728fe795 631 Gene3D G3DSA:3.30.70.20 572 622 1.3E-10 T 23-10-2018 TAM4_506 92126895ed8756854984d059728fe795 631 Pfam PF01472 PUA domain 134 204 6.1E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_506 92126895ed8756854984d059728fe795 631 Gene3D G3DSA:3.40.50.620 214 479 1.5E-50 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_506 92126895ed8756854984d059728fe795 631 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 429 1.2E-45 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TAM4_506 92126895ed8756854984d059728fe795 631 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 92 201 1.9E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_506 92126895ed8756854984d059728fe795 631 Pfam PF12838 4Fe-4S dicluster domain 576 618 1.3E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 25 205 1.6E-61 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 26 191 3.6E-69 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 Gene3D G3DSA:2.20.25.420 18 69 4.7E-6 T 23-10-2018 TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 Pfam PF03367 ZPR1 zinc-finger domain 25 181 7.5E-40 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 SMART SM00709 24 184 3.6E-76 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TAM4_174 16f3ebd3a1e5f55cb2b7941298b42ed2 236 Gene3D G3DSA:2.60.120.1040 73 200 7.8E-23 T 23-10-2018 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 PRINTS PR00094 Adenylate kinase signature 32 46 3.7E-27 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 PRINTS PR00094 Adenylate kinase signature 175 189 3.7E-27 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 PRINTS PR00094 Adenylate kinase signature 4 17 3.7E-27 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 PRINTS PR00094 Adenylate kinase signature 158 173 3.7E-27 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 PRINTS PR00094 Adenylate kinase signature 79 95 3.7E-27 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 7.1E-20 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 Pfam PF00406 Adenylate kinase 5 188 4.1E-41 T 23-10-2018 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 Gene3D G3DSA:3.40.50.300 1 220 5.6E-74 T 23-10-2018 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 210 1.5E-72 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 SUPERFAMILY SSF52540 1 211 1.02E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_927 2ff806e6e3dc6d175f3ee1f301464a18 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 46.492 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 Gene3D G3DSA:3.90.550.10 1 237 2.6E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 345 4.7E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 293 0.0012 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 SUPERFAMILY SSF53448 1 299 6.34E-74 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 SUPERFAMILY SSF51161 301 346 1.39E-7 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 Gene3D G3DSA:2.160.10.10 238 372 6.7E-18 T 23-10-2018 TAM4_2212 bb6171a0e2365d4d526a16b1b91baf2a 413 Pfam PF00483 Nucleotidyl transferase 2 230 2.0E-46 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_1752 ce06fbd37a6a78cc97c700d09781d020 235 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 79 2.5E-15 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TAM4_1752 ce06fbd37a6a78cc97c700d09781d020 235 Gene3D G3DSA:3.20.20.190 5 234 4.8E-33 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TAM4_1752 ce06fbd37a6a78cc97c700d09781d020 235 SUPERFAMILY SSF51695 8 232 8.11E-30 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 456 2.4E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 SUPERFAMILY SSF51971 156 407 5.53E-71 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 Gene3D G3DSA:3.50.50.60 293 479 2.9E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 Gene3D G3DSA:3.50.50.60 153 282 7.3E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 SUPERFAMILY SSF46548 5 167 1.99E-32 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 415 7.1E-24 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 7.1E-24 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 425 447 7.1E-24 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 7.1E-24 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 SUPERFAMILY SSF51971 341 472 5.12E-16 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 471 1.9E-211 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 139 2.7E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 Gene3D G3DSA:1.10.1060.10 4 152 2.8E-40 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 1.2E-16 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 1.2E-16 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 414 1.2E-16 T 23-10-2018 TAM4_859 ab1848fe2a5c3e6b47b4d7920257699a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 447 1.2E-16 T 23-10-2018 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.8E-16 T 23-10-2018 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 5.4E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 5.4E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 5.4E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 SUPERFAMILY SSF46785 3 60 1.06E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 SMART SM00344 4 105 9.9E-11 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 Gene3D G3DSA:3.30.70.920 57 160 9.1E-40 T 23-10-2018 TAM4_2138 6894250d279a81d8d3867ade97bb460f 160 Gene3D G3DSA:1.10.10.10 1 56 7.3E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_842 08103a23da7d40154f39c8723228cd33 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 82 3.0E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_842 08103a23da7d40154f39c8723228cd33 86 SUPERFAMILY SSF57829 10 80 1.1E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_842 08103a23da7d40154f39c8723228cd33 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.097 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_842 08103a23da7d40154f39c8723228cd33 86 Gene3D G3DSA:2.20.25.30 9 86 3.7E-32 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_842 08103a23da7d40154f39c8723228cd33 86 Pfam PF01780 Ribosomal L37ae protein family 3 83 1.1E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 Gene3D G3DSA:3.30.930.10 107 438 2.7E-122 T 23-10-2018 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 SUPERFAMILY SSF50249 1 101 2.48E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 2.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 1.2E-183 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 5.8E-97 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.866 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 Gene3D G3DSA:2.40.50.140 1 105 3.0E-28 T 23-10-2018 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 SUPERFAMILY SSF55681 96 437 5.9E-100 T 23-10-2018 TAM4_289 d8a6c17dc87b6a7c2a035e5908bcc7d0 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 2.1E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 SMART SM00857 63 200 1.1E-28 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 SUPERFAMILY SSF53041 63 191 1.03E-23 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 Pfam PF00239 Resolvase, N terminal domain 63 195 5.2E-27 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 Gene3D G3DSA:1.10.1660.10 8 64 2.0E-14 T 23-10-2018 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 SUPERFAMILY SSF46955 6 56 8.7E-12 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TAM4_2048 00f5128339014732f190dda7a4e801f0 209 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 2.7E-10 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 Gene3D G3DSA:3.40.50.1390 65 160 5.0E-27 T 23-10-2018 TAM4_2048 00f5128339014732f190dda7a4e801f0 209 Pfam PF12728 Helix-turn-helix domain 7 54 2.5E-12 T 23-10-2018 TAM4_906 914be70e5fe5bbe7fa426d4eee6bb9c6 451 SUPERFAMILY SSF52540 1 204 3.65E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_906 914be70e5fe5bbe7fa426d4eee6bb9c6 451 Gene3D G3DSA:3.40.50.300 1 167 1.3E-23 T 23-10-2018 TAM4_906 914be70e5fe5bbe7fa426d4eee6bb9c6 451 SUPERFAMILY SSF46785 245 317 1.3E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_906 914be70e5fe5bbe7fa426d4eee6bb9c6 451 Pfam PF01637 ATPase domain predominantly from Archaea 3 202 1.3E-11 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_906 914be70e5fe5bbe7fa426d4eee6bb9c6 451 Pfam PF03008 Archaea bacterial proteins of unknown function 312 399 2.9E-15 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_1687 0b7747942dce3b976d71072e430f31cc 136 SMART SM01405 15 135 1.6E-51 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1687 0b7747942dce3b976d71072e430f31cc 136 Pfam PF01092 Ribosomal protein S6e 15 135 7.7E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1687 0b7747942dce3b976d71072e430f31cc 136 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 13 136 19.036 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 2.1E-183 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 2.8E-243 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 SUPERFAMILY SSF48592 17 524 9.42E-93 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 Gene3D G3DSA:1.10.560.10 28 522 9.9E-214 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 Gene3D G3DSA:3.30.260.10 147 405 9.9E-214 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 SUPERFAMILY SSF54849 150 405 1.98E-28 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 SUPERFAMILY SSF52029 212 378 1.15E-63 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 Gene3D G3DSA:3.50.7.10 218 369 9.9E-214 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.1E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.1E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.1E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.1E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1352 5724a2e627793cb8d29c65060a4fafbe 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.1E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_1084 3ec1cfb6ddc7830f2b27ae195d506d91 298 Pfam PF12706 Beta-lactamase superfamily domain 26 205 7.9E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1084 3ec1cfb6ddc7830f2b27ae195d506d91 298 Gene3D G3DSA:3.60.15.10 7 272 3.3E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1084 3ec1cfb6ddc7830f2b27ae195d506d91 298 PIRSF PIRSF004944 1 298 2.8E-114 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TAM4_1084 3ec1cfb6ddc7830f2b27ae195d506d91 298 Hamap MF_01406 UPF0282 protein . 1 285 39.272 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TAM4_1084 3ec1cfb6ddc7830f2b27ae195d506d91 298 SUPERFAMILY SSF56281 1 261 3.28E-18 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1666 7e8ebf74634547d2d09617a654edd351 150 Gene3D G3DSA:3.90.190.10 3 148 6.1E-31 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TAM4_1666 7e8ebf74634547d2d09617a654edd351 150 Pfam PF00782 Dual specificity phosphatase, catalytic domain 50 141 2.2E-15 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 TAM4_1666 7e8ebf74634547d2d09617a654edd351 150 SUPERFAMILY SSF52799 3 145 5.71E-32 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TAM4_1666 7e8ebf74634547d2d09617a654edd351 150 SMART SM00195 1 143 8.3E-6 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 TAM4_1666 7e8ebf74634547d2d09617a654edd351 150 SMART SM00404 49 139 8.3E-4 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic TAM4_80 d95e91c619d3f5263d195d3957ebc5b5 113 SUPERFAMILY SSF46785 4 107 1.31E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_80 d95e91c619d3f5263d195d3957ebc5b5 113 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 2.6E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TAM4_80 d95e91c619d3f5263d195d3957ebc5b5 113 Gene3D G3DSA:1.10.10.10 2 111 1.1E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1329 4e4ad781986b9f31b8b51365a886c961 185 Gene3D G3DSA:3.40.225.10 3 185 6.6E-62 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TAM4_1329 4e4ad781986b9f31b8b51365a886c961 185 SUPERFAMILY SSF53639 6 183 1.96E-56 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TAM4_1329 4e4ad781986b9f31b8b51365a886c961 185 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 180 1.8E-48 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TAM4_1329 4e4ad781986b9f31b8b51365a886c961 185 SMART SM01007 7 181 8.7E-59 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 Gene3D G3DSA:3.40.50.300 1 226 1.1E-37 T 23-10-2018 TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 Gene3D G3DSA:3.40.50.300 681 880 2.3E-36 T 23-10-2018 TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 SUPERFAMILY SSF75712 391 487 1.07E-12 T 23-10-2018 TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 Gene3D G3DSA:1.10.287.510 386 499 6.7E-11 T 23-10-2018 TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 SUPERFAMILY SSF52540 623 874 4.97E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 SMART SM00382 22 873 0.005 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 879 12.287 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 SUPERFAMILY SSF52540 1 874 1.22E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1567 119452d2452c68c73ed6ccf7a3354f26 885 Pfam PF04423 Rad50 zinc hook motif 417 464 6.2E-7 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 Pfam PF13429 Tetratricopeptide repeat 165 248 1.3E-6 T 23-10-2018 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 Pfam PF13181 Tetratricopeptide repeat 260 284 0.076 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SMART SM00028 255 288 150.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SMART SM00028 293 326 440.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SMART SM00028 217 250 3.8 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SMART SM00028 153 186 81.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SUPERFAMILY SSF48452 130 329 1.61E-25 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 SUPERFAMILY SSF103473 5 107 5.23E-6 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1356 d326cd6451642bb6b38125c8dca37766 339 Gene3D G3DSA:1.25.40.10 101 335 6.9E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 Pfam PF05343 M42 glutamyl aminopeptidase 41 322 6.8E-86 T 23-10-2018 IPR008007 Peptidase M42 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 SUPERFAMILY SSF53187 2 329 1.39E-53 T 23-10-2018 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 PIRSF PIRSF001123 1 330 2.4E-86 T 23-10-2018 IPR008007 Peptidase M42 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 SUPERFAMILY SSF101821 64 171 3.66E-21 T 23-10-2018 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 Gene3D G3DSA:2.40.30.40 63 154 7.4E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TAM4_514 4739903543e7772b0ff74db0e7e4e2ea 330 Gene3D G3DSA:3.40.630.10 7 323 7.4E-114 T 23-10-2018 TAM4_1967 160a5833151949fc0f102132df1e7732 463 SUPERFAMILY SSF52210 139 298 1.01E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1967 160a5833151949fc0f102132df1e7732 463 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 296 1.2E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TAM4_1967 160a5833151949fc0f102132df1e7732 463 Pfam PF13380 CoA binding domain 13 142 3.1E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1967 160a5833151949fc0f102132df1e7732 463 SUPERFAMILY SSF51735 6 137 9.89E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1967 160a5833151949fc0f102132df1e7732 463 Gene3D G3DSA:3.40.50.261 300 463 5.3E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1967 160a5833151949fc0f102132df1e7732 463 Gene3D G3DSA:3.40.50.720 4 137 2.9E-45 T 23-10-2018 TAM4_1967 160a5833151949fc0f102132df1e7732 463 SMART SM00881 9 108 1.3E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1967 160a5833151949fc0f102132df1e7732 463 SUPERFAMILY SSF52210 302 459 2.09E-33 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1967 160a5833151949fc0f102132df1e7732 463 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 7 455 2.7E-187 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 TAM4_1967 160a5833151949fc0f102132df1e7732 463 Gene3D G3DSA:3.40.50.261 138 299 1.4E-65 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_165 d41177c607f80af263379dc99139122c 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 7.2E-19 T 23-10-2018 TAM4_165 d41177c607f80af263379dc99139122c 152 SUPERFAMILY SSF54909 61 144 3.62E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_165 d41177c607f80af263379dc99139122c 152 SUPERFAMILY SSF46785 1 61 4.47E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_165 d41177c607f80af263379dc99139122c 152 Gene3D G3DSA:3.30.70.920 53 146 2.4E-24 T 23-10-2018 TAM4_165 d41177c607f80af263379dc99139122c 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 2.5E-17 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_165 d41177c607f80af263379dc99139122c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_165 d41177c607f80af263379dc99139122c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_165 d41177c607f80af263379dc99139122c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_165 d41177c607f80af263379dc99139122c 152 SMART SM00344 1 107 1.5E-44 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_165 d41177c607f80af263379dc99139122c 152 Gene3D G3DSA:1.10.10.10 1 51 8.2E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2149 4b43169f328b82364cebf41789fae786 378 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 377 2.1E-95 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TAM4_2149 4b43169f328b82364cebf41789fae786 378 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 378 42.782 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 TAM4_2149 4b43169f328b82364cebf41789fae786 378 SUPERFAMILY SSF53335 4 376 3.23E-107 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_2149 4b43169f328b82364cebf41789fae786 378 Gene3D G3DSA:3.30.56.70 320 377 2.8E-20 T 23-10-2018 TAM4_2149 4b43169f328b82364cebf41789fae786 378 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 11 376 3.7E-114 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TAM4_2149 4b43169f328b82364cebf41789fae786 378 Gene3D G3DSA:3.40.50.150 1 319 5.2E-101 T 23-10-2018 TAM4_526 0a5784e669128107f84f8628ef752b33 194 Gene3D G3DSA:3.40.50.12280 7 174 2.5E-52 T 23-10-2018 TAM4_526 0a5784e669128107f84f8628ef752b33 194 SUPERFAMILY SSF56770 17 166 4.58E-52 T 23-10-2018 TAM4_526 0a5784e669128107f84f8628ef752b33 194 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 153 4.5E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_526 0a5784e669128107f84f8628ef752b33 194 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 36 147 5.2E-19 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 Pfam PF01866 Putative diphthamide synthesis protein 26 319 7.7E-75 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 8 313 1.1E-87 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 Gene3D G3DSA:3.40.50.11850 100 208 1.3E-41 T 23-10-2018 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 Gene3D G3DSA:3.40.50.11840 5 98 1.8E-29 T 23-10-2018 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 324 7.7E-113 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 Gene3D G3DSA:3.40.50.11860 212 313 6.1E-35 T 23-10-2018 TAM4_694 4b4f19439f163e30efc5274f6a2572d5 344 PIRSF PIRSF004967 3 336 8.5E-78 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_1395 6852217df5f9ec875fcb9222df39f8eb 90 Gene3D G3DSA:1.10.10.1100 1 67 1.5E-21 T 23-10-2018 TAM4_1395 6852217df5f9ec875fcb9222df39f8eb 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 8.3E-14 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 Hamap MF_00645 Protein . 5 188 42.398 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 Gene3D G3DSA:3.30.700.20 6 197 1.2E-75 T 23-10-2018 IPR027485 AMMECR1, N-terminal TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 7.4E-69 T 23-10-2018 IPR023473 AMMECR1 TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 Pfam PF01871 AMMECR1 13 190 7.3E-55 T 23-10-2018 IPR002733 AMMECR1 domain TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 SUPERFAMILY SSF143447 4 202 1.12E-70 T 23-10-2018 IPR036071 AMMECR1 domain superfamily TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 Gene3D G3DSA:3.30.1490.150 113 186 1.2E-75 T 23-10-2018 TAM4_1600 2a62c041fa7611cff5a3fe1a78db277f 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 4.4E-60 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 4 226 1.9E-78 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 SUPERFAMILY SSF56784 2 229 2.8E-37 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 69 2.7E-9 T 23-10-2018 TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 Pfam PF08282 haloacid dehalogenase-like hydrolase 155 236 2.9E-7 T 23-10-2018 TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 4 232 4.1E-66 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 Gene3D G3DSA:3.40.50.1000 4 221 2.0E-63 T 23-10-2018 IPR023214 HAD superfamily TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 Gene3D G3DSA:3.30.980.20 98 180 2.0E-63 T 23-10-2018 TAM4_517 3c47e853ca750d0b64be735b2c6005a4 247 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 225 1.9E-18 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TAM4_2051 c06ccdc27bd340b9a4ba406fdf596feb 444 Pfam PF08532 Beta-galactosidase trimerisation domain 103 209 8.7E-7 T 23-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TAM4_2051 c06ccdc27bd340b9a4ba406fdf596feb 444 SUPERFAMILY SSF46785 381 433 3.24E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2051 c06ccdc27bd340b9a4ba406fdf596feb 444 SUPERFAMILY SSF52317 31 210 1.27E-9 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_2051 c06ccdc27bd340b9a4ba406fdf596feb 444 Gene3D G3DSA:3.40.50.880 32 231 7.1E-14 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1986 97827ee44ebe62ad368f64cac93ef4ef 138 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1986 97827ee44ebe62ad368f64cac93ef4ef 138 Pfam PF00037 4Fe-4S binding domain 67 87 7.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1986 97827ee44ebe62ad368f64cac93ef4ef 138 SUPERFAMILY SSF54862 18 94 8.05E-14 T 23-10-2018 TAM4_1986 97827ee44ebe62ad368f64cac93ef4ef 138 Gene3D G3DSA:3.30.70.20 17 88 3.1E-8 T 23-10-2018 TAM4_2387 10bd69f1c772d8ffd7cae025b3e8f7cb 188 Pfam PF04199 Putative cyclase 3 134 1.9E-24 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TAM4_2387 10bd69f1c772d8ffd7cae025b3e8f7cb 188 SUPERFAMILY SSF102198 2 187 1.57E-54 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TAM4_2387 10bd69f1c772d8ffd7cae025b3e8f7cb 188 Gene3D G3DSA:3.50.30.50 1 187 6.9E-57 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TAM4_1614 527e50243741c50854c5689259594b76 178 SUPERFAMILY SSF54211 75 164 1.26E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1614 527e50243741c50854c5689259594b76 178 SUPERFAMILY SSF54211 2 73 5.31E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1614 527e50243741c50854c5689259594b76 178 Gene3D G3DSA:3.30.230.40 1 75 1.9E-21 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TAM4_1614 527e50243741c50854c5689259594b76 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TAM4_1614 527e50243741c50854c5689259594b76 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 1.0E-37 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TAM4_1614 527e50243741c50854c5689259594b76 178 Gene3D G3DSA:3.30.230.40 76 176 1.4E-33 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TAM4_1407 4b0e33dd125982dc3056334fe9755a16 1292 Pfam PF03833 DNA polymerase II large subunit DP2 12 962 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1407 4b0e33dd125982dc3056334fe9755a16 1292 PIRSF PIRSF016275 3 1213 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1407 4b0e33dd125982dc3056334fe9755a16 1292 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 9 1200 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_1407 4b0e33dd125982dc3056334fe9755a16 1292 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1227 523.281 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_461 67e3920f74b6912c3e9929f0da5536b4 501 Gene3D G3DSA:3.30.40.60 415 501 1.3E-7 T 23-10-2018 TAM4_461 67e3920f74b6912c3e9929f0da5536b4 501 SMART SM00507 434 490 0.0047 T 23-10-2018 IPR003615 HNH nuclease TAM4_461 67e3920f74b6912c3e9929f0da5536b4 501 Pfam PF03235 Protein of unknown function DUF262 34 209 8.9E-22 T 23-10-2018 IPR004919 Domain of unknown function DUF262 TAM4_461 67e3920f74b6912c3e9929f0da5536b4 501 Pfam PF13395 HNH endonuclease 449 493 4.0E-7 T 23-10-2018 IPR003615 HNH nuclease TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 13 28 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 Pfam PF01209 ubiE/COQ5 methyltransferase family 2 210 3.3E-51 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 2 226 2.3E-65 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 SUPERFAMILY SSF53335 2 221 6.54E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 Gene3D G3DSA:3.40.50.150 8 228 1.6E-57 T 23-10-2018 TAM4_2017 0a1072643dbbcfd03ab6c58a18f5d114 229 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 228 31.044 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 Gene3D G3DSA:3.30.1370.10 118 223 1.4E-32 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 SUPERFAMILY SSF54791 40 114 1.35E-13 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 214 6.6E-68 T 23-10-2018 IPR019964 KH domain protein, archaea TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 Gene3D G3DSA:3.30.1370.10 35 117 6.0E-35 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 SUPERFAMILY SSF54791 127 204 8.77E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 Pfam PF00013 KH domain 39 86 6.4E-10 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 Pfam PF00013 KH domain 142 189 2.0E-5 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 SMART SM00322 35 105 7.4E-11 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_1702 f61efaaf8af046bf14063b87f2132143 232 SMART SM00322 126 193 1.9E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_1324 d54abce22393680706bf9ac808e42b52 172 Gene3D G3DSA:3.30.930.10 1 170 5.4E-69 T 23-10-2018 TAM4_1324 d54abce22393680706bf9ac808e42b52 172 SUPERFAMILY SSF142913 3 170 2.59E-51 T 23-10-2018 TAM4_1324 d54abce22393680706bf9ac808e42b52 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 8.3E-69 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 TAM4_287 3ee69f1c3c2f2b7f82bde6d2610b00e6 215 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 111 203 5.0E-42 T 23-10-2018 TAM4_287 3ee69f1c3c2f2b7f82bde6d2610b00e6 215 Pfam PF01876 RNase P subunit p30 16 204 5.5E-34 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TAM4_287 3ee69f1c3c2f2b7f82bde6d2610b00e6 215 Gene3D G3DSA:3.20.20.140 1 214 2.4E-97 T 23-10-2018 TAM4_287 3ee69f1c3c2f2b7f82bde6d2610b00e6 215 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 5 215 22.051 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 TAM4_287 3ee69f1c3c2f2b7f82bde6d2610b00e6 215 SUPERFAMILY SSF89550 7 212 4.32E-33 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 Pfam PF12862 Anaphase-promoting complex subunit 5 213 238 46.0 T 23-10-2018 IPR026000 Anaphase-promoting complex subunit 5 domain Reactome: R-HSA-141430|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-176407|Reactome: R-HSA-176408|Reactome: R-HSA-176409|Reactome: R-HSA-176412|Reactome: R-HSA-179409|Reactome: R-HSA-2467813|Reactome: R-HSA-2559582|Reactome: R-HSA-69017|Reactome: R-HSA-983168 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SUPERFAMILY SSF48452 50 237 4.17E-27 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 Gene3D G3DSA:1.25.40.10 49 242 8.3E-33 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SMART SM00028 54 87 0.045 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SMART SM00028 210 243 75.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SMART SM00028 133 166 9.2 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SMART SM00028 92 125 7.7E-4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 SMART SM00028 173 206 28.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 Pfam PF13424 Tetratricopeptide repeat 56 120 1.9E-9 T 23-10-2018 TAM4_1311 cf98424b0134c8ce849fb0915e8e8686 340 Pfam PF13424 Tetratricopeptide repeat 132 202 1.1E-10 T 23-10-2018 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 SUPERFAMILY SSF103025 3 307 7.53E-96 T 23-10-2018 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Gene3D G3DSA:3.30.70.1400 52 143 3.7E-91 T 23-10-2018 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 287 3.4E-98 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 382 3.7E-26 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Gene3D G3DSA:4.10.1250.10 268 305 6.9E-10 T 23-10-2018 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Gene3D G3DSA:3.30.1360.120 8 255 3.7E-91 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 PIRSF PIRSF006487 1 398 1.6E-106 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Gene3D G3DSA:2.40.30.110 309 383 1.1E-31 T 23-10-2018 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.578 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 SUPERFAMILY SSF101790 300 392 7.52E-26 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TAM4_1339 00fd05004529db3c6962ab12dc595a07 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 2.5E-96 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TAM4_685 851561a017c80da8d75813c714a7c611 197 PIRSF PIRSF005639 1 197 4.0E-69 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_685 851561a017c80da8d75813c714a7c611 197 SUPERFAMILY SSF52317 2 194 5.16E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_685 851561a017c80da8d75813c714a7c611 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 6.4E-76 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_685 851561a017c80da8d75813c714a7c611 197 Gene3D G3DSA:3.40.50.880 1 197 6.3E-69 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_685 851561a017c80da8d75813c714a7c611 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_685 851561a017c80da8d75813c714a7c611 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 1.4E-57 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_685 851561a017c80da8d75813c714a7c611 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.685 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_420 02ad68bbbc73537a494198dd3385e9c9 261 Pfam PF01435 Peptidase family M48 55 253 2.0E-22 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TAM4_420 02ad68bbbc73537a494198dd3385e9c9 261 Gene3D G3DSA:3.30.2010.10 49 131 9.8E-15 T 23-10-2018 TAM4_661 3927b52fd149eadd5739d9a3f7c38c05 624 Pfam PF00361 Proton-conducting membrane transporter 126 426 1.5E-56 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1262 f08ec2e92aa75cf58e7eb646659b0e33 241 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 9 234 1.1E-63 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 TAM4_1262 f08ec2e92aa75cf58e7eb646659b0e33 241 SUPERFAMILY SSF159659 10 229 5.23E-47 T 23-10-2018 TAM4_1262 f08ec2e92aa75cf58e7eb646659b0e33 241 Pfam PF09754 PAC2 family 18 221 2.1E-45 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TAM4_1262 f08ec2e92aa75cf58e7eb646659b0e33 241 Gene3D G3DSA:3.40.50.10900 1 241 1.2E-71 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TAM4_1879 2742dd7a7010b59ce9ecaaa6cc2b6eb3 114 Gene3D G3DSA:3.40.30.10 16 110 1.9E-15 T 23-10-2018 TAM4_1879 2742dd7a7010b59ce9ecaaa6cc2b6eb3 114 SUPERFAMILY SSF52833 7 111 2.27E-15 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_1879 2742dd7a7010b59ce9ecaaa6cc2b6eb3 114 Pfam PF13192 Thioredoxin domain 32 106 4.5E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 SMART SM00796 1 199 9.3E-116 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 SUPERFAMILY SSF160467 3 89 8.89E-23 T 23-10-2018 TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 SUPERFAMILY SSF50891 85 215 8.72E-53 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 Gene3D G3DSA:3.30.1360.40 1 83 1.1E-26 T 23-10-2018 TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 208 6.4E-75 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 199 4.5E-80 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TAM4_1936 ca8c63d2fedd475e7c448320a61c8a93 228 Gene3D G3DSA:2.40.100.10 84 224 1.9E-66 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TAM4_1611 f43b9211bd4cad0815523e49cbf78a5c 218 SUPERFAMILY SSF56281 13 217 1.82E-21 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1611 f43b9211bd4cad0815523e49cbf78a5c 218 Pfam PF00753 Metallo-beta-lactamase superfamily 22 77 5.3E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1611 f43b9211bd4cad0815523e49cbf78a5c 218 Gene3D G3DSA:3.60.15.10 99 218 1.1E-21 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1611 f43b9211bd4cad0815523e49cbf78a5c 218 Gene3D G3DSA:3.60.15.10 1 93 1.7E-18 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2003 625026349740818c5fe70d7431587cb3 88 Pfam PF01247 Ribosomal protein L35Ae 5 87 3.7E-14 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2003 625026349740818c5fe70d7431587cb3 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 1.0E-30 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2003 625026349740818c5fe70d7431587cb3 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 23.498 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2003 625026349740818c5fe70d7431587cb3 88 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 56 77 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2003 625026349740818c5fe70d7431587cb3 88 Gene3D G3DSA:2.40.10.190 3 88 1.4E-23 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2003 625026349740818c5fe70d7431587cb3 88 SUPERFAMILY SSF50447 5 87 3.0E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_1602 40e414a55f3c86ebcac60f1953bfe198 387 Pfam PF04123 Domain of unknown function (DUF373) 2 339 3.5E-96 T 23-10-2018 IPR007254 Protein of unknown function DUF373 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 PIRSF PIRSF005067 1 172 1.6E-43 T 23-10-2018 IPR016437 MCT-1/Tma20 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 7.0E-7 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 Gene3D G3DSA:3.10.450.120 1 78 4.1E-33 T 23-10-2018 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 1.4E-30 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 SUPERFAMILY SSF88697 88 169 1.6E-23 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 SMART SM00359 88 163 7.6E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 Pfam PF01472 PUA domain 89 161 1.9E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 Gene3D G3DSA:2.30.130.10 79 171 9.6E-36 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_19 9616dc688a58e3bac7733e67cbd22374 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 2.4E-58 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 TAM4_483 b19c123f71afac59415ece645c772e10 378 Gene3D G3DSA:1.20.1250.20 1 356 4.5E-40 T 23-10-2018 TAM4_483 b19c123f71afac59415ece645c772e10 378 Pfam PF07690 Major Facilitator Superfamily 2 259 1.6E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_483 b19c123f71afac59415ece645c772e10 378 SUPERFAMILY SSF103473 2 359 6.93E-40 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 PIRSF PIRSF002181 1 142 5.1E-43 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 SUPERFAMILY SSF52161 2 142 1.7E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 Pfam PF00572 Ribosomal protein L13 3 103 3.1E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 5.4E-65 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 Gene3D G3DSA:3.90.1180.10 1 142 1.1E-57 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_43 1d07b01101b8aa497b86b0f6a674c96c 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.567 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TAM4_1633 2256a2aa9c0092c5950a42dd0cf04680 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 3.8E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TAM4_1633 2256a2aa9c0092c5950a42dd0cf04680 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.448 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TAM4_1633 2256a2aa9c0092c5950a42dd0cf04680 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 120 1.1E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 272 299 5.7E-5 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 Gene3D G3DSA:3.90.550.10 1 237 2.8E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 2.4E-163 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 SUPERFAMILY SSF53448 1 304 1.69E-76 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 Gene3D G3DSA:2.160.10.10 238 351 1.2E-14 T 23-10-2018 TAM4_299 d73b51764bbb52fc03ef5f300a303c49 352 Pfam PF00483 Nucleotidyl transferase 2 234 3.7E-52 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_98 8a8726d0ed4e9038c1f7cb52512b81a9 383 Gene3D G3DSA:3.30.420.40 148 309 1.0E-5 T 23-10-2018 TAM4_98 8a8726d0ed4e9038c1f7cb52512b81a9 383 PIRSF PIRSF009433 1 380 3.5E-152 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TAM4_98 8a8726d0ed4e9038c1f7cb52512b81a9 383 SUPERFAMILY SSF53067 4 306 4.64E-11 T 23-10-2018 TAM4_98 8a8726d0ed4e9038c1f7cb52512b81a9 383 Pfam PF07318 Protein of unknown function (DUF1464) 6 369 2.3E-99 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TAM4_2061 6dbeedbcfd830eb2c3fca4735d68db83 125 SUPERFAMILY SSF88723 1 110 2.52E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2061 6dbeedbcfd830eb2c3fca4735d68db83 125 Gene3D G3DSA:3.40.50.1010 2 119 1.2E-13 T 23-10-2018 TAM4_2061 6dbeedbcfd830eb2c3fca4735d68db83 125 Pfam PF01850 PIN domain 3 110 3.8E-16 T 23-10-2018 IPR002716 PIN domain TAM4_1420 6daefde511e21a98bdb37a179dd9e8c2 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 3.3E-55 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TAM4_1420 6daefde511e21a98bdb37a179dd9e8c2 315 Gene3D G3DSA:3.90.25.10 223 315 2.4E-26 T 23-10-2018 TAM4_1420 6daefde511e21a98bdb37a179dd9e8c2 315 Gene3D G3DSA:3.90.25.10 180 222 2.1E-12 T 23-10-2018 TAM4_1420 6daefde511e21a98bdb37a179dd9e8c2 315 Gene3D G3DSA:3.40.50.720 1 179 2.9E-50 T 23-10-2018 TAM4_1420 6daefde511e21a98bdb37a179dd9e8c2 315 SUPERFAMILY SSF51735 1 313 8.42E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1415 79f2b9553754888ca0406cdeb34a47e5 377 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 208 368 3.7E-19 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TAM4_1415 79f2b9553754888ca0406cdeb34a47e5 377 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 4 192 9.2E-30 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TAM4_1415 79f2b9553754888ca0406cdeb34a47e5 377 Gene3D G3DSA:3.40.50.11570 1 201 2.0E-42 T 23-10-2018 TAM4_1415 79f2b9553754888ca0406cdeb34a47e5 377 Gene3D G3DSA:3.40.50.11570 202 377 1.3E-28 T 23-10-2018 TAM4_366 4b50556b2fb97c0d8951d1984431f582 197 Pfam PF13189 Cytidylate kinase-like family 7 160 1.2E-24 T 23-10-2018 TAM4_366 4b50556b2fb97c0d8951d1984431f582 197 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 3.3E-61 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TAM4_366 4b50556b2fb97c0d8951d1984431f582 197 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.513 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TAM4_366 4b50556b2fb97c0d8951d1984431f582 197 SUPERFAMILY SSF52540 7 175 7.5E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_366 4b50556b2fb97c0d8951d1984431f582 197 Gene3D G3DSA:3.40.50.300 2 177 4.2E-45 T 23-10-2018 TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 SUPERFAMILY SSF52540 3 225 7.57E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 Gene3D G3DSA:3.40.50.300 1 237 3.1E-66 T 23-10-2018 TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 Pfam PF00005 ABC transporter 19 165 4.9E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 SMART SM00382 28 213 6.7E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1062 93cfc8655dbec667a42b74f2789b5145 308 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 304 4.7E-106 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TAM4_1930 7bc32afbba4d2145d44256f4690f1f96 171 SUPERFAMILY SSF89028 3 164 2.16E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TAM4_1930 7bc32afbba4d2145d44256f4690f1f96 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 1.9E-57 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TAM4_1930 7bc32afbba4d2145d44256f4690f1f96 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 6.1E-49 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TAM4_1930 7bc32afbba4d2145d44256f4690f1f96 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 19 164 9.0E-55 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TAM4_1930 7bc32afbba4d2145d44256f4690f1f96 171 Gene3D G3DSA:1.20.1200.10 23 171 5.0E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 6.7E-6 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 6.7E-6 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 1.1E-80 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 2.0E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase TAM4_993 9262139d068e091e5f85f1ab848f039e 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 44.697 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.4E-11 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-11 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.4E-11 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.4E-11 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 8.1E-10 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 8.1E-10 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 8.1E-10 T 23-10-2018 TAM4_993 9262139d068e091e5f85f1ab848f039e 188 Gene3D G3DSA:3.40.50.880 1 187 1.0E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_993 9262139d068e091e5f85f1ab848f039e 188 SUPERFAMILY SSF52317 1 186 2.14E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1978 370eea5138819d4977b4fcf72233ee0f 95 Gene3D G3DSA:1.20.1270.90 5 84 1.9E-25 T 23-10-2018 TAM4_1978 370eea5138819d4977b4fcf72233ee0f 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 2.7E-30 T 23-10-2018 IPR023140 Domain of unknown function DUF357 TAM4_1978 370eea5138819d4977b4fcf72233ee0f 95 SUPERFAMILY SSF158372 5 85 7.98E-26 T 23-10-2018 IPR036809 AF1782-like superfamily TAM4_350 c22b68ce135ddacaef1c7e65ace1f778 244 Gene3D G3DSA:3.20.20.20 158 219 2.2E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TAM4_350 c22b68ce135ddacaef1c7e65ace1f778 244 Pfam PF04060 Putative Fe-S cluster 160 191 1.5E-8 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 TAM4_350 c22b68ce135ddacaef1c7e65ace1f778 244 Gene3D G3DSA:3.40.50.300 1 157 4.2E-28 T 23-10-2018 TAM4_350 c22b68ce135ddacaef1c7e65ace1f778 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 110 8.4E-18 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TAM4_350 c22b68ce135ddacaef1c7e65ace1f778 244 SUPERFAMILY SSF52540 1 102 5.04E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 752 770 2.5E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 Pfam PF08308 PEGA domain 573 640 2.4E-16 T 23-10-2018 IPR013229 PEGA TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 Pfam PF08308 PEGA domain 643 710 2.6E-18 T 23-10-2018 IPR013229 PEGA TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 SUPERFAMILY SSF49344 330 566 7.06E-68 T 23-10-2018 TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 SUPERFAMILY SSF52317 88 286 1.28E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 Gene3D G3DSA:2.60.40.1190 327 571 6.1E-63 T 23-10-2018 TAM4_2060 6dc1cecd36c5b9352be26ab19d648fb8 771 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 330 564 1.1E-70 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 TIGRFAM TIGR00835 agcS: amino acid carrier protein 206 511 3.9E-91 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 Pfam PF01235 Sodium:alanine symporter family 55 174 1.9E-35 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 Pfam PF01235 Sodium:alanine symporter family 204 513 1.4E-97 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 Gene3D G3DSA:1.20.1740.10 198 514 6.7E-7 T 23-10-2018 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 480 500 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 272 291 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 363 381 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 408 430 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 244 262 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1159 9ce189aae6804dab44efc1aae4b06b0c 516 PRINTS PR00175 Sodium/alanine symporter signature 92 114 1.5E-53 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TAM4_1955 38c7887fd420824a0119374191aac13d 290 Pfam PF03600 Citrate transporter 5 227 9.8E-13 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TAM4_1896 72a10741475a50df88512c79e70e1ea7 138 Pfam PF04900 Fcf1 32 130 1.5E-7 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 TAM4_1896 72a10741475a50df88512c79e70e1ea7 138 Gene3D G3DSA:3.40.50.1010 7 136 2.2E-29 T 23-10-2018 TAM4_1896 72a10741475a50df88512c79e70e1ea7 138 SMART SM00670 7 113 1.0E-7 T 23-10-2018 IPR002716 PIN domain TAM4_1896 72a10741475a50df88512c79e70e1ea7 138 SUPERFAMILY SSF88723 7 130 2.2E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 SUPERFAMILY SSF55186 95 241 1.44E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Pfam PF02272 DHHA1 domain 271 404 1.7E-13 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Gene3D G3DSA:3.30.980.10 92 248 1.8E-40 T 23-10-2018 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 SUPERFAMILY SSF50447 1 89 3.25E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 1.7E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Gene3D G3DSA:2.40.30.130 1 89 1.5E-22 T 23-10-2018 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 SMART SM00863 191 234 2.5E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Gene3D G3DSA:3.10.310.40 302 404 1.4E-8 T 23-10-2018 TAM4_2441 a87b0e092f731018940bb95331a8aa25 405 Pfam PF01411 tRNA synthetases class II (A) 23 94 2.4E-12 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Pfam PF00575 S1 RNA binding domain 130 193 7.8E-11 T 23-10-2018 IPR003029 S1 domain GO:0003676 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Gene3D G3DSA:3.90.1640.30 333 531 4.7E-9 T 23-10-2018 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 SUPERFAMILY SSF50249 121 193 1.19E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 SUPERFAMILY SSF50249 225 296 2.23E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 7.3E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 SUPERFAMILY SSF64182 336 735 6.54E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Gene3D G3DSA:2.10.230.10 1 88 8.2E-7 T 23-10-2018 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Gene3D G3DSA:2.40.50.140 128 202 2.3E-13 T 23-10-2018 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 SMART SM00316 131 196 2.2E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 Gene3D G3DSA:2.40.50.140 218 305 9.8E-8 T 23-10-2018 TAM4_1651 5b44fe71ae5db6318e37acc1cca1eb1c 741 SUPERFAMILY SSF57938 4 32 5.23E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TAM4_1929 6fba9d03668ed10d354bcdb4a1d5b3ff 190 Gene3D G3DSA:3.60.21.10 5 127 1.5E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_1929 6fba9d03668ed10d354bcdb4a1d5b3ff 190 Pfam PF00149 Calcineurin-like phosphoesterase 22 113 4.7E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_1929 6fba9d03668ed10d354bcdb4a1d5b3ff 190 SUPERFAMILY SSF56300 21 160 5.0E-21 T 23-10-2018 TAM4_1 cfe207073c82a826cd58df5c780afe58 155 Gene3D G3DSA:1.10.15.30 60 114 7.5E-56 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type TAM4_1 cfe207073c82a826cd58df5c780afe58 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 82.62 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TAM4_1 cfe207073c82a826cd58df5c780afe58 155 SUPERFAMILY SSF55129 5 155 1.44E-49 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TAM4_1 cfe207073c82a826cd58df5c780afe58 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.1E-16 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TAM4_1 cfe207073c82a826cd58df5c780afe58 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site TAM4_1 cfe207073c82a826cd58df5c780afe58 155 Gene3D G3DSA:3.30.1390.20 5 143 7.5E-56 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TAM4_1 cfe207073c82a826cd58df5c780afe58 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 4.6E-62 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TAM4_997 67790fe88868ea311c83e41b58fbb30c 142 Pfam PF01850 PIN domain 5 134 9.8E-20 T 23-10-2018 IPR002716 PIN domain TAM4_997 67790fe88868ea311c83e41b58fbb30c 142 SUPERFAMILY SSF88723 1 130 5.89E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_997 67790fe88868ea311c83e41b58fbb30c 142 SMART SM00670 2 131 9.0E-10 T 23-10-2018 IPR002716 PIN domain TAM4_997 67790fe88868ea311c83e41b58fbb30c 142 Gene3D G3DSA:3.40.50.1010 4 139 1.8E-14 T 23-10-2018 TAM4_2065 736fded3db0b0ef0f80917e31f030ef1 233 SUPERFAMILY SSF56300 3 233 1.55E-66 T 23-10-2018 TAM4_2065 736fded3db0b0ef0f80917e31f030ef1 233 PIRSF PIRSF000883 1 233 3.9E-73 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 TAM4_2065 736fded3db0b0ef0f80917e31f030ef1 233 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 195 8.8E-16 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TAM4_2065 736fded3db0b0ef0f80917e31f030ef1 233 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 195 1.0E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TAM4_2065 736fded3db0b0ef0f80917e31f030ef1 233 Gene3D G3DSA:3.60.21.10 2 233 6.7E-72 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_688 ccfed24d385b3c4918ea8a8293a3e230 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 292 77.179 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TAM4_688 ccfed24d385b3c4918ea8a8293a3e230 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 288 3.9E-82 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TAM4_688 ccfed24d385b3c4918ea8a8293a3e230 294 Pfam PF03186 CobD/Cbib protein 8 268 2.9E-82 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TAM4_1406 1158c60621ac330c44e5c80445b66ad2 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1406 1158c60621ac330c44e5c80445b66ad2 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 1.5E-10 T 23-10-2018 TAM4_1406 1158c60621ac330c44e5c80445b66ad2 105 Gene3D G3DSA:3.30.70.20 18 105 4.9E-16 T 23-10-2018 TAM4_1406 1158c60621ac330c44e5c80445b66ad2 105 SUPERFAMILY SSF54862 30 104 2.49E-25 T 23-10-2018 TAM4_1406 1158c60621ac330c44e5c80445b66ad2 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 33 104 3.1E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 TIGRFAM TIGR00373 TIGR00373: transcription factor E 13 166 1.7E-50 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 SUPERFAMILY SSF46785 9 89 2.94E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 SMART SM00531 21 160 2.5E-57 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 PIRSF PIRSF006373 1 179 2.5E-68 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 Pfam PF02002 TFIIE alpha subunit 15 112 3.5E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 Hamap MF_01909 Transcription factor E [tfe]. 5 168 26.692 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TAM4_1202 4c66fc9e471459cc710aacc2c594cd9c 210 Gene3D G3DSA:1.10.10.10 6 89 4.2E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_434 65622de334851cceb9ca70d5cb237706 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 224 1.1E-46 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TAM4_434 65622de334851cceb9ca70d5cb237706 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 29.921 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TAM4_434 65622de334851cceb9ca70d5cb237706 231 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 1.1E-39 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TAM4_1753 794b6968dc3b1815d53780a645e1ea0d 116 Gene3D G3DSA:1.10.287.370 1 116 3.0E-40 T 23-10-2018 IPR009053 Prefoldin TAM4_1753 794b6968dc3b1815d53780a645e1ea0d 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 4.6E-40 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TAM4_1753 794b6968dc3b1815d53780a645e1ea0d 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 49.716 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TAM4_1753 794b6968dc3b1815d53780a645e1ea0d 116 Pfam PF01920 Prefoldin subunit 9 110 2.7E-25 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_1753 794b6968dc3b1815d53780a645e1ea0d 116 SUPERFAMILY SSF46579 6 109 1.57E-24 T 23-10-2018 TAM4_1114 71d311fccac7afbe27c4e21551cd38c4 394 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 386 27.245 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 TAM4_1114 71d311fccac7afbe27c4e21551cd38c4 394 SUPERFAMILY SSF140914 2 247 5.23E-19 T 23-10-2018 TAM4_1114 71d311fccac7afbe27c4e21551cd38c4 394 Gene3D G3DSA:2.20.20.80 104 168 1.3E-38 T 23-10-2018 TAM4_1114 71d311fccac7afbe27c4e21551cd38c4 394 Gene3D G3DSA:1.20.930.50 8 221 1.3E-38 T 23-10-2018 TAM4_1114 71d311fccac7afbe27c4e21551cd38c4 394 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 140 358 2.5E-28 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 SMART SM00986 31 185 7.4E-37 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 SMART SM00987 31 185 7.4E-37 T 23-10-2018 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 Pfam PF03167 Uracil DNA glycosylase superfamily 31 184 1.9E-46 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 3.3E-76 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 Gene3D G3DSA:3.40.470.10 5 192 4.2E-70 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_56 5dd7eaab0b911880a22a77927ec90aab 194 SUPERFAMILY SSF52141 7 192 1.41E-60 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 9.7E-221 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 Gene3D G3DSA:3.30.70.150 1 136 3.3E-45 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 Gene3D G3DSA:3.20.20.110 137 438 6.5E-127 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 SUPERFAMILY SSF51649 136 441 5.5E-107 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 SUPERFAMILY SSF54966 3 136 2.22E-38 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.706 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 9.8E-96 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_1764 8f55374ab230010d07af2565dcf3433e 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 130 1.6E-44 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TAM4_670 c69fcd6944ef337014161d1c1ffa0434 59 SUPERFAMILY SSF47113 8 59 1.12E-6 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_1104 42561b7d9c5a102a41c6dd134370f1b1 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1104 42561b7d9c5a102a41c6dd134370f1b1 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1104 42561b7d9c5a102a41c6dd134370f1b1 168 Pfam PF12838 4Fe-4S dicluster domain 41 91 2.5E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1104 42561b7d9c5a102a41c6dd134370f1b1 168 Gene3D G3DSA:3.30.70.3270 20 124 1.6E-24 T 23-10-2018 TAM4_1104 42561b7d9c5a102a41c6dd134370f1b1 168 SUPERFAMILY SSF54862 20 121 1.67E-22 T 23-10-2018 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 15 638 9.6E-281 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 Gene3D G3DSA:3.30.300.30 516 645 1.6E-32 T 23-10-2018 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 Gene3D G3DSA:3.40.50.12780 43 513 1.5E-106 T 23-10-2018 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 SUPERFAMILY SSF56801 12 636 3.79E-178 T 23-10-2018 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 250 261 - T 23-10-2018 IPR020845 AMP-binding, conserved site TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 19 72 5.4E-22 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 1.1E-28 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TAM4_1436 c6ba80ce5825ac9800f93c788a881796 646 Pfam PF00501 AMP-binding enzyme 79 519 5.5E-89 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TAM4_611 c6384599b98149b541294a684ee9c57c 627 Pfam PF00326 Prolyl oligopeptidase family 413 604 1.3E-50 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TAM4_611 c6384599b98149b541294a684ee9c57c 627 Gene3D G3DSA:3.40.50.1820 2 595 2.6E-132 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_611 c6384599b98149b541294a684ee9c57c 627 Gene3D G3DSA:2.130.10.120 48 360 2.6E-132 T 23-10-2018 TAM4_611 c6384599b98149b541294a684ee9c57c 627 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 68 350 4.0E-19 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TAM4_611 c6384599b98149b541294a684ee9c57c 627 SUPERFAMILY SSF53474 366 596 6.12E-48 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 473 493 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 528 543 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 393 411 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 546 568 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 419 443 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 447 466 1.2E-53 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TAM4_611 c6384599b98149b541294a684ee9c57c 627 SUPERFAMILY SSF50993 1 350 7.32E-45 T 23-10-2018 TAM4_1036 f38eb4b950dfed278e5afc0a386c3f76 154 Gene3D G3DSA:3.40.50.2020 1 154 7.3E-54 T 23-10-2018 TAM4_1036 f38eb4b950dfed278e5afc0a386c3f76 154 Pfam PF00156 Phosphoribosyl transferase domain 11 150 1.8E-29 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_1036 f38eb4b950dfed278e5afc0a386c3f76 154 SUPERFAMILY SSF53271 2 146 5.77E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_442 867d2121a4907ee8fcae42381dd06192 324 SMART SM00382 38 237 3.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_442 867d2121a4907ee8fcae42381dd06192 324 SUPERFAMILY SSF52540 4 251 1.98E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_442 867d2121a4907ee8fcae42381dd06192 324 Gene3D G3DSA:3.40.50.300 2 324 1.2E-105 T 23-10-2018 TAM4_442 867d2121a4907ee8fcae42381dd06192 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 320 2.1E-30 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_442 867d2121a4907ee8fcae42381dd06192 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 300 6.1E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_442 867d2121a4907ee8fcae42381dd06192 324 Pfam PF00005 ABC transporter 30 180 1.3E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_442 867d2121a4907ee8fcae42381dd06192 324 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1551 83c29ecdabe2cb81739fb98122297964 65 Pfam PF01667 Ribosomal protein S27 11 64 4.0E-27 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1551 83c29ecdabe2cb81739fb98122297964 65 SUPERFAMILY SSF57829 11 65 1.37E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_1551 83c29ecdabe2cb81739fb98122297964 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.598 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1551 83c29ecdabe2cb81739fb98122297964 65 Gene3D G3DSA:2.20.25.100 11 65 9.3E-26 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily TAM4_1551 83c29ecdabe2cb81739fb98122297964 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1480 5de35e54394b02490b647d0f72336afa 378 Gene3D G3DSA:1.20.1090.10 185 378 3.8E-54 T 23-10-2018 TAM4_1480 5de35e54394b02490b647d0f72336afa 378 Gene3D G3DSA:3.40.50.1970 1 183 9.0E-44 T 23-10-2018 TAM4_1480 5de35e54394b02490b647d0f72336afa 378 SUPERFAMILY SSF56796 2 377 2.36E-98 T 23-10-2018 TAM4_1480 5de35e54394b02490b647d0f72336afa 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 6.7E-99 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 6 140 4.2E-24 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 26 41 1.7E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 85 96 1.7E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 SUPERFAMILY SSF51306 18 119 2.35E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 Gene3D G3DSA:2.10.109.10 27 105 8.1E-6 T 23-10-2018 TAM4_94 c1fc76163bf21c7292556a3ac2f652e0 181 Pfam PF00717 Peptidase S24-like 26 78 2.3E-10 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TAM4_2021 3e14dd7e85ea98fec40761d70276b400 413 SMART SM00471 47 185 2.3E-12 T 23-10-2018 IPR003607 HD/PDEase domain TAM4_2021 3e14dd7e85ea98fec40761d70276b400 413 Pfam PF01966 HD domain 51 121 1.4E-15 T 23-10-2018 IPR006674 HD domain TAM4_2021 3e14dd7e85ea98fec40761d70276b400 413 SUPERFAMILY SSF109604 2 408 3.46E-91 T 23-10-2018 TAM4_2021 3e14dd7e85ea98fec40761d70276b400 413 Gene3D G3DSA:1.10.3210.10 1 283 5.2E-84 T 23-10-2018 TAM4_1514 53ebf606934862f78742b436027132d6 215 Pfam PF00177 Ribosomal protein S7p/S5e 54 215 2.6E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain TAM4_1514 53ebf606934862f78742b436027132d6 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 1.3E-89 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1514 53ebf606934862f78742b436027132d6 215 PIRSF PIRSF002122 1 215 5.9E-48 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TAM4_1514 53ebf606934862f78742b436027132d6 215 SUPERFAMILY SSF47973 16 215 9.68E-63 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TAM4_1514 53ebf606934862f78742b436027132d6 215 Gene3D G3DSA:1.10.455.10 15 215 8.9E-79 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TAM4_1514 53ebf606934862f78742b436027132d6 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.301 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal TAM4_679 cdc33bf0d23a81c352adfc0346b9b006 565 SUPERFAMILY SSF53187 11 422 3.82E-31 T 23-10-2018 TAM4_679 cdc33bf0d23a81c352adfc0346b9b006 565 Pfam PF04389 Peptidase family M28 229 415 1.3E-16 T 23-10-2018 IPR007484 Peptidase M28 TAM4_679 cdc33bf0d23a81c352adfc0346b9b006 565 Gene3D G3DSA:3.40.630.10 30 408 4.5E-47 T 23-10-2018 TAM4_679 cdc33bf0d23a81c352adfc0346b9b006 565 Gene3D G3DSA:3.50.30.30 73 209 4.5E-47 T 23-10-2018 TAM4_762 4974d31aa73db4021685d221b8358e1a 205 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 15 196 1.5E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TAM4_762 4974d31aa73db4021685d221b8358e1a 205 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 7 197 5.3E-92 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 TAM4_762 4974d31aa73db4021685d221b8358e1a 205 Gene3D G3DSA:3.40.920.10 4 204 8.8E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_762 4974d31aa73db4021685d221b8358e1a 205 SUPERFAMILY SSF53323 7 202 3.66E-45 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 375 425 5.9E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 SMART SM00849 14 225 1.5E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 SUPERFAMILY SSF56281 2 443 2.54E-64 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 Gene3D G3DSA:3.40.50.10710 219 378 5.1E-133 T 23-10-2018 TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 444 7.9E-155 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 Hamap MF_01492 Ribonuclease J [rnj]. 1 444 48.978 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 Pfam PF00753 Metallo-beta-lactamase superfamily 28 187 1.1E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 382 410 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site TAM4_243 7a62b0978dc330709db99a36fe2f2025 444 Gene3D G3DSA:3.60.15.10 6 443 5.1E-133 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2475 d56b656ff5fd64ce1479d19573645788 222 SUPERFAMILY SSF159612 2 220 1.44E-109 T 23-10-2018 TAM4_2475 d56b656ff5fd64ce1479d19573645788 222 Gene3D G3DSA:3.90.79.30 101 220 1.2E-67 T 23-10-2018 TAM4_2475 d56b656ff5fd64ce1479d19573645788 222 Pfam PF15517 TBP-interacting protein N-terminus 3 102 7.8E-39 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal TAM4_2475 d56b656ff5fd64ce1479d19573645788 222 Gene3D G3DSA:3.40.1350.70 1 100 8.8E-51 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 Gene3D G3DSA:3.30.200.20 1 50 5.1E-26 T 23-10-2018 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.457 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 Pfam PF01269 Fibrillarin 4 224 3.4E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 204 225 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 123 152 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 98 115 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 153 182 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 23 42 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 73 94 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PRINTS PR00052 Fibrillarin signature 46 65 2.4E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 Gene3D G3DSA:3.40.50.150 51 226 5.0E-74 T 23-10-2018 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 SUPERFAMILY SSF53335 3 225 2.47E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 PIRSF PIRSF006540 1 226 7.4E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_717 4b3ba62a8e9b0d5cc16137a457c7c4d7 226 SMART SM01206 3 226 6.3E-147 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TAM4_356 8297bbf3c765c53c26a8410e6f1fe91b 263 SMART SM00382 26 210 4.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_356 8297bbf3c765c53c26a8410e6f1fe91b 263 Pfam PF00005 ABC transporter 18 151 1.8E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_356 8297bbf3c765c53c26a8410e6f1fe91b 263 SUPERFAMILY SSF52540 2 201 6.48E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_356 8297bbf3c765c53c26a8410e6f1fe91b 263 Gene3D G3DSA:3.40.50.300 1 212 2.0E-44 T 23-10-2018 TAM4_1158 54fd0f1444c862dd0f733d01d7d70e20 173 SUPERFAMILY SSF56770 31 160 1.96E-53 T 23-10-2018 TAM4_1158 54fd0f1444c862dd0f733d01d7d70e20 173 Gene3D G3DSA:3.40.50.12280 7 168 6.0E-52 T 23-10-2018 TAM4_1158 54fd0f1444c862dd0f733d01d7d70e20 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 43 152 6.7E-28 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SUPERFAMILY SSF55608 505 621 1.93E-8 T 23-10-2018 IPR027434 Homing endonuclease TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SUPERFAMILY SSF51294 212 686 2.16E-13 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 212 309 1.5E-7 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Gene3D G3DSA:3.30.230.10 900 1104 1.7E-78 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SMART SM00305 640 691 5.3E-4 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SUPERFAMILY SSF52540 30 882 1.7E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Gene3D G3DSA:3.10.28.10 413 596 5.5E-11 T 23-10-2018 IPR027434 Homing endonuclease TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Gene3D G3DSA:3.40.50.300 620 788 4.6E-33 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Gene3D G3DSA:3.40.50.300 14 127 8.3E-31 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 903 1083 1.1E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Pfam PF01078 Magnesium chelatase, subunit ChlI 35 87 9.1E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SMART SM00306 210 329 9.5E-12 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 908 924 2.0E-28 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 1038 1056 2.0E-28 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 985 1004 2.0E-28 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 1015 1034 2.0E-28 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 61 80 2.0E-28 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 18 1096 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 SUPERFAMILY SSF54211 908 1081 2.73E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Gene3D G3DSA:1.10.8.60 789 881 1.3E-43 T 23-10-2018 TAM4_750 7ef5a19e4f081f1098c19c5d7c42ccbf 1104 Pfam PF13654 AAA domain 691 879 1.3E-17 T 23-10-2018 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 SMART SM00363 103 165 4.4E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 Pfam PF01479 S4 domain 103 148 2.6E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.391 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 SMART SM01390 5 102 1.4E-10 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 5.3E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 Gene3D G3DSA:3.10.290.10 102 177 2.7E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TAM4_223 3d279666f2ff133e9266052ad362bb21 180 SUPERFAMILY SSF55174 9 160 1.09E-34 T 23-10-2018 TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 Gene3D G3DSA:3.30.70.20 23 73 8.9E-6 T 23-10-2018 TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 Gene3D G3DSA:3.30.70.20 74 105 4.1E-8 T 23-10-2018 TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 SUPERFAMILY SSF54862 26 103 5.59E-24 T 23-10-2018 TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 3.9E-11 T 23-10-2018 TAM4_1397 0680b4d833f6b958b93ffd1b19fce3df 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 104 7.1E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 1.1E-62 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 Gene3D G3DSA:3.40.50.150 149 439 1.2E-87 T 23-10-2018 TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 SUPERFAMILY SSF53335 143 439 6.63E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 7.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 7.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 7.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 7.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 7.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 204 2.5E-9 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_956 fe2ec4695ff8efeb0e68b10a08778315 443 Gene3D G3DSA:1.10.940.10 1 148 1.4E-39 T 23-10-2018 IPR035926 NusB-like superfamily TAM4_312 374724cc4b750224f054a4e584b6d690 479 SUPERFAMILY SSF56235 4 209 6.26E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_312 374724cc4b750224f054a4e584b6d690 479 SUPERFAMILY SSF52402 219 461 1.59E-55 T 23-10-2018 TAM4_312 374724cc4b750224f054a4e584b6d690 479 Pfam PF00733 Asparagine synthase 364 453 6.1E-20 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TAM4_312 374724cc4b750224f054a4e584b6d690 479 Pfam PF00733 Asparagine synthase 235 361 9.8E-33 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TAM4_312 374724cc4b750224f054a4e584b6d690 479 Gene3D G3DSA:3.60.20.10 2 220 5.5E-45 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_312 374724cc4b750224f054a4e584b6d690 479 Gene3D G3DSA:3.40.50.620 221 467 2.7E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_312 374724cc4b750224f054a4e584b6d690 479 PIRSF PIRSF001589 1 378 1.4E-55 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TAM4_312 374724cc4b750224f054a4e584b6d690 479 PIRSF PIRSF001589 362 464 3.4E-17 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TAM4_312 374724cc4b750224f054a4e584b6d690 479 Pfam PF13537 Glutamine amidotransferase domain 60 178 6.8E-24 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 SUPERFAMILY SSF55159 5 91 4.32E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 PIRSF PIRSF037511 5 97 3.5E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 96 4.4E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 Gene3D G3DSA:3.30.780.10 20 98 1.2E-28 T 23-10-2018 TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 Pfam PF01253 Translation initiation factor SUI1 20 90 1.6E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 TAM4_277 c7c067b064df53aaf867df5cef0326bf 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.787 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea TAM4_1342 07c0c007673e18aea7e0d8952fede480 249 Gene3D G3DSA:3.40.1350.10 124 235 1.2E-43 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TAM4_1342 07c0c007673e18aea7e0d8952fede480 249 Hamap MF_00722 Endonuclease NucS [nucS]. 28 239 39.166 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TAM4_1342 07c0c007673e18aea7e0d8952fede480 249 Gene3D G3DSA:2.70.180.20 1 123 3.0E-44 T 23-10-2018 TAM4_1342 07c0c007673e18aea7e0d8952fede480 249 Pfam PF01939 Endonuclease NucS 28 243 1.5E-83 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TAM4_1401 ce39a2a880319176ff33f086e770ef3e 299 SUPERFAMILY SSF52540 18 265 5.65E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1401 ce39a2a880319176ff33f086e770ef3e 299 Gene3D G3DSA:3.40.50.300 17 280 4.1E-83 T 23-10-2018 TAM4_1401 ce39a2a880319176ff33f086e770ef3e 299 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 TAM4_1401 ce39a2a880319176ff33f086e770ef3e 299 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.322 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TAM4_1401 ce39a2a880319176ff33f086e770ef3e 299 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 9.1E-97 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 416 8.2E-29 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 3.2E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Gene3D G3DSA:3.40.50.720 190 349 3.6E-178 T 23-10-2018 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 51.124 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 140 9.8E-36 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 SMART SM00996 6 420 1.6E-143 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 SMART SM00997 188 349 6.4E-111 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 PIRSF PIRSF001109 1 421 3.9E-199 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 SUPERFAMILY SSF52283 5 421 1.13E-103 T 23-10-2018 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 Gene3D G3DSA:3.40.50.1480 9 410 3.6E-178 T 23-10-2018 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 SUPERFAMILY SSF51735 188 350 9.38E-69 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1708 b4a743ef86fe1dcb53f9a7331bb83938 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 7.3E-212 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 344 2.3E-30 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 SUPERFAMILY SSF55347 118 286 1.11E-40 T 23-10-2018 TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 SUPERFAMILY SSF51735 2 168 6.24E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 Gene3D G3DSA:3.40.50.720 2 344 1.7E-127 T 23-10-2018 TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 Gene3D G3DSA:3.30.360.10 118 294 1.7E-127 T 23-10-2018 TAM4_1810 4b78c9d47ec84348222c2d364cec2836 357 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 1.7E-19 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 219 39.523 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 SMART SM01133 2 217 2.5E-115 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 Gene3D G3DSA:3.20.20.70 1 221 1.9E-106 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 215 2.0E-91 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 PIRSF PIRSF001357 1 222 1.3E-90 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 Pfam PF01791 DeoC/LacD family aldolase 5 212 3.1E-23 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1188 9061157a76545fb7704b4a724a90348f 222 SUPERFAMILY SSF51569 1 218 5.76E-93 T 23-10-2018 TAM4_433 940f018b20ce23bb357881664ef846d6 439 Gene3D G3DSA:3.40.50.1170 81 301 8.3E-88 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 SMART SM00870 94 417 3.0E-159 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 1.2E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 1.2E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 1.2E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 Pfam PF00710 Asparaginase, N-terminal 94 288 1.4E-64 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 Gene3D G3DSA:3.40.50.40 302 439 8.0E-56 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 Gene3D G3DSA:2.30.30.520 2 79 5.9E-23 T 23-10-2018 IPR037222 GatD, N-terminal TAM4_433 940f018b20ce23bb357881664ef846d6 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TAM4_433 940f018b20ce23bb357881664ef846d6 439 PIRSF PIRSF001220 89 428 5.6E-113 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 SUPERFAMILY SSF141300 4 74 1.83E-20 T 23-10-2018 IPR037222 GatD, N-terminal TAM4_433 940f018b20ce23bb357881664ef846d6 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 5.7E-147 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TAM4_433 940f018b20ce23bb357881664ef846d6 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 48.803 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TAM4_433 940f018b20ce23bb357881664ef846d6 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 3.8E-196 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TAM4_433 940f018b20ce23bb357881664ef846d6 439 PIRSF PIRSF500175 13 437 4.5E-188 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TAM4_433 940f018b20ce23bb357881664ef846d6 439 SUPERFAMILY SSF53774 89 436 2.62E-120 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TAM4_1332 9f204b70b270bb333dc288024758bc79 122 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 116 11.068 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_1332 9f204b70b270bb333dc288024758bc79 122 Pfam PF01850 PIN domain 1 109 4.3E-10 T 23-10-2018 IPR002716 PIN domain TAM4_1332 9f204b70b270bb333dc288024758bc79 122 Gene3D G3DSA:3.40.50.1010 1 121 3.2E-29 T 23-10-2018 TAM4_1332 9f204b70b270bb333dc288024758bc79 122 SUPERFAMILY SSF88723 1 119 4.21E-25 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 SUPERFAMILY SSF103473 23 409 7.46E-56 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 PRINTS PR01035 Tetracycline resistance protein signature 37 53 1.1E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 PRINTS PR01035 Tetracycline resistance protein signature 151 173 1.1E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 PRINTS PR01035 Tetracycline resistance protein signature 361 384 1.1E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 PRINTS PR01035 Tetracycline resistance protein signature 300 321 1.1E-5 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 Gene3D G3DSA:1.20.1250.20 22 207 2.2E-29 T 23-10-2018 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 Gene3D G3DSA:1.20.1250.20 239 410 1.6E-25 T 23-10-2018 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 Pfam PF07690 Major Facilitator Superfamily 273 407 1.8E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1411 bd046f879aa5df64be0cbfd00dec7f7f 411 Pfam PF07690 Major Facilitator Superfamily 32 269 2.7E-24 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 Pfam PF01411 tRNA synthetases class II (A) 13 87 4.5E-12 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 SUPERFAMILY SSF55186 85 210 3.53E-31 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 SUPERFAMILY SSF50447 1 84 1.66E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 SMART SM00863 165 208 1.9E-6 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 Gene3D G3DSA:3.30.980.10 85 212 1.9E-40 T 23-10-2018 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 208 3.7E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_1622 9bfa7aea2083c06b19fe9f0b0ef702ae 213 Gene3D G3DSA:2.40.30.130 13 84 2.6E-32 T 23-10-2018 TAM4_364 3f2066d27aef240647d26d875479c907 66 Gene3D G3DSA:1.10.287.310 1 66 4.2E-19 T 23-10-2018 TAM4_364 3f2066d27aef240647d26d875479c907 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.0 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_364 3f2066d27aef240647d26d875479c907 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_364 3f2066d27aef240647d26d875479c907 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 1.4E-20 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_364 3f2066d27aef240647d26d875479c907 66 SUPERFAMILY SSF46561 1 61 1.7E-15 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_364 3f2066d27aef240647d26d875479c907 66 Pfam PF00831 Ribosomal L29 protein 4 61 1.8E-16 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_601 f38f5327e77f3df1452145c7a94d979c 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 42 3.7E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_601 f38f5327e77f3df1452145c7a94d979c 80 SMART SM00966 4 49 3.3E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_601 f38f5327e77f3df1452145c7a94d979c 80 SUPERFAMILY SSF89447 2 44 6.67E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_601 f38f5327e77f3df1452145c7a94d979c 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 45 7.5E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_601 f38f5327e77f3df1452145c7a94d979c 80 Gene3D G3DSA:2.10.260.10 1 42 1.2E-15 T 23-10-2018 TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 SUPERFAMILY SSF51735 29 127 5.51E-5 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 111 2.0E-30 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 Gene3D G3DSA:3.40.50.150 1 132 2.1E-26 T 23-10-2018 TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 Hamap MF_00341 UPF0146 protein . 2 131 26.935 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 PIRSF PIRSF016725 1 132 1.7E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TAM4_523 67381f9ba8f5a325cf16c3cf478e6fc6 132 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 130 5.8E-32 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TAM4_2499 37f7926a68de0d5b48764abe35587133 460 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 258 331 1.2E-14 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_2499 37f7926a68de0d5b48764abe35587133 460 Pfam PF01385 Probable transposase 195 289 8.1E-9 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TAM4_2499 37f7926a68de0d5b48764abe35587133 460 Pfam PF07282 Putative transposase DNA-binding domain 317 369 6.7E-16 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_2470 b466ec42f1c9c1cfa9701b05255c4aff 136 Hamap MF_00674 UPF0251 protein . 36 133 23.02 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TAM4_2470 b466ec42f1c9c1cfa9701b05255c4aff 136 Pfam PF02001 Protein of unknown function DUF134 35 124 1.3E-24 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TAM4_2470 b466ec42f1c9c1cfa9701b05255c4aff 136 SUPERFAMILY SSF88659 70 116 1.01E-8 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TAM4_2470 b466ec42f1c9c1cfa9701b05255c4aff 136 Gene3D G3DSA:1.10.10.10 69 118 7.0E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_341 1c9ec43c727b619e9dfb6cee2715e01d 152 SUPERFAMILY SSF55620 11 150 1.83E-35 T 23-10-2018 TAM4_341 1c9ec43c727b619e9dfb6cee2715e01d 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 6.3E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TAM4_341 1c9ec43c727b619e9dfb6cee2715e01d 152 Gene3D G3DSA:3.30.479.10 12 150 2.9E-33 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TAM4_1391 498372bc9fd510ff7a0b66267eaa7540 191 SUPERFAMILY SSF53448 1 185 7.43E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1391 498372bc9fd510ff7a0b66267eaa7540 191 Gene3D G3DSA:3.90.550.10 4 191 1.1E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1391 498372bc9fd510ff7a0b66267eaa7540 191 Pfam PF12804 MobA-like NTP transferase domain 3 156 2.4E-29 T 23-10-2018 IPR025877 MobA-like NTP transferase TAM4_1391 498372bc9fd510ff7a0b66267eaa7540 191 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 20.65 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 Gene3D G3DSA:3.40.50.300 1 208 3.1E-43 T 23-10-2018 TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 Pfam PF01637 ATPase domain predominantly from Archaea 15 250 2.5E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 Gene3D G3DSA:1.10.8.60 209 286 2.9E-26 T 23-10-2018 TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 Gene3D G3DSA:1.10.10.10 287 356 4.1E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 SUPERFAMILY SSF46785 285 354 1.56E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2301 f5f00e454a889e9d3bad38ce612183fc 356 SUPERFAMILY SSF52540 1 280 2.02E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1948 ee869f935287f17c4779bf0bc560f33e 260 Pfam PF01975 Survival protein SurE 3 193 1.2E-53 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TAM4_1948 ee869f935287f17c4779bf0bc560f33e 260 SUPERFAMILY SSF64167 1 256 1.11E-70 T 23-10-2018 TAM4_1948 ee869f935287f17c4779bf0bc560f33e 260 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 260 33.962 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TAM4_1948 ee869f935287f17c4779bf0bc560f33e 260 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 243 4.9E-69 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TAM4_1948 ee869f935287f17c4779bf0bc560f33e 260 Gene3D G3DSA:3.40.1210.10 1 256 4.7E-83 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 Gene3D G3DSA:2.40.30.20 1 77 1.5E-18 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 PIRSF PIRSF000498 1 185 9.1E-59 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 Gene3D G3DSA:2.40.30.20 90 184 9.0E-31 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 182 4.2E-51 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 SUPERFAMILY SSF63380 1 81 5.53E-17 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 SUPERFAMILY SSF63380 81 182 1.96E-30 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 Pfam PF00677 Lumazine binding domain 3 75 2.2E-13 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_1942 e9948f9366ee753abe5a6c715269803e 185 Pfam PF00677 Lumazine binding domain 88 171 2.6E-22 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 SUPERFAMILY SSF55945 3 88 1.49E-23 T 23-10-2018 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 Gene3D G3DSA:3.30.310.10 92 177 3.3E-30 T 23-10-2018 IPR012295 TBP domain superfamily TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 139 155 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 5 20 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 48 66 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 120 135 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 96 112 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 PRINTS PR00686 Transcription initiation factor TFIID signature 29 48 1.2E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 179 30.199 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 4 82 2.7E-21 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 94 175 2.6E-26 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 Gene3D G3DSA:3.30.310.10 10 91 1.1E-24 T 23-10-2018 IPR012295 TBP domain superfamily TAM4_1052 69ca71994fc69705553f89adc3de3b4a 182 SUPERFAMILY SSF55945 91 178 4.71E-25 T 23-10-2018 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 Gene3D G3DSA:3.40.50.150 75 412 3.1E-115 T 23-10-2018 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 Gene3D G3DSA:2.40.50.140 1 73 5.4E-15 T 23-10-2018 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 250 417 1.4E-21 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 SUPERFAMILY SSF50249 3 60 3.6E-9 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_104 f30277d6e34595539d2e60c992cfe735 418 Gene3D G3DSA:3.40.1350.30 114 259 3.1E-115 T 23-10-2018 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 400 410 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TAM4_104 f30277d6e34595539d2e60c992cfe735 418 SUPERFAMILY SSF53335 61 417 9.17E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_104 f30277d6e34595539d2e60c992cfe735 418 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 410 1.6E-81 T 23-10-2018 TAM4_104 f30277d6e34595539d2e60c992cfe735 418 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 349 380 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 PIRSF PIRSF001123 1 337 3.5E-36 T 23-10-2018 IPR008007 Peptidase M42 TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 Gene3D G3DSA:2.40.30.40 70 164 2.1E-110 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 SUPERFAMILY SSF53187 2 334 9.95E-48 T 23-10-2018 TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 Pfam PF05343 M42 glutamyl aminopeptidase 52 327 7.4E-69 T 23-10-2018 IPR008007 Peptidase M42 TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 SUPERFAMILY SSF101821 67 178 1.68E-26 T 23-10-2018 TAM4_2210 67d52d8068611418f247b4b1e2d2b3e5 338 Gene3D G3DSA:3.40.630.10 11 332 2.1E-110 T 23-10-2018 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 SUPERFAMILY SSF54826 4 125 5.13E-30 T 23-10-2018 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 Gene3D G3DSA:3.30.390.10 1 111 1.9E-20 T 23-10-2018 IPR029017 Enolase-like, N-terminal TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 Gene3D G3DSA:3.20.20.120 223 339 1.2E-11 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 SUPERFAMILY SSF51604 113 337 4.71E-29 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 Pfam PF03952 Enolase, N-terminal domain 38 119 1.9E-22 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 248 334 8.7E-6 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 PRINTS PR00148 Enolase signature 92 108 4.9E-6 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 PRINTS PR00148 Enolase signature 316 330 4.9E-6 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 SMART SM01192 124 340 2.3E-13 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_204 f42e68bb452bcb970a198a1bda0c4f81 341 SMART SM01193 4 119 1.2E-34 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_444 9a799e6fd971543055e4c4e929dde210 163 Gene3D G3DSA:3.60.21.10 1 162 6.1E-40 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_444 9a799e6fd971543055e4c4e929dde210 163 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 153 1.2E-33 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TAM4_444 9a799e6fd971543055e4c4e929dde210 163 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 4.6E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TAM4_444 9a799e6fd971543055e4c4e929dde210 163 SUPERFAMILY SSF56300 2 153 7.05E-37 T 23-10-2018 TAM4_1971 5f120c52b6939d45954197024a515e10 216 Gene3D G3DSA:3.40.390.10 77 206 2.3E-23 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TAM4_1971 5f120c52b6939d45954197024a515e10 216 SUPERFAMILY SSF55486 151 198 1.25E-6 T 23-10-2018 TAM4_1971 5f120c52b6939d45954197024a515e10 216 PIRSF PIRSF005785 10 208 3.6E-40 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TAM4_1971 5f120c52b6939d45954197024a515e10 216 Pfam PF07998 Peptidase family M54 16 201 8.1E-52 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TAM4_189 d90efa98b66ec3803cf844b554ffd386 168 Pfam PF03692 Putative zinc- or iron-chelating domain 29 134 9.2E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TAM4_582 234751532eb4db90941a038c58a3fc3d 656 PIRSF PIRSF005023 1 123 1.8E-43 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 PIRSF PIRSF005023 115 656 1.5E-200 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 Gene3D G3DSA:3.40.50.2030 268 435 1.9E-73 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 Gene3D G3DSA:1.20.1270.30 63 267 1.1E-77 T 23-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 SUPERFAMILY SSF56821 4 656 7.72E-195 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 Gene3D G3DSA:3.40.50.2030 438 653 8.9E-82 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 Pfam PF03063 Prismane/CO dehydrogenase family 46 636 2.4E-161 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_582 234751532eb4db90941a038c58a3fc3d 656 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 123 656 4.0E-173 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_2064 4e895eefc80a0e6c3cd2cd801805736b 67 SUPERFAMILY SSF141694 1 62 1.49E-13 T 23-10-2018 TAM4_2064 4e895eefc80a0e6c3cd2cd801805736b 67 Gene3D G3DSA:4.10.1150.10 1 67 2.3E-8 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_2064 4e895eefc80a0e6c3cd2cd801805736b 67 Pfam PF01954 Protein of unknown function DUF104 2 57 2.6E-13 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 SUPERFAMILY SSF51735 3 176 1.18E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 Gene3D G3DSA:3.40.50.720 5 324 1.1E-89 T 23-10-2018 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 Gene3D G3DSA:3.30.360.10 166 307 1.1E-89 T 23-10-2018 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 SUPERFAMILY SSF55347 155 311 1.96E-35 T 23-10-2018 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 147 1.2E-7 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 Pfam PF00742 Homoserine dehydrogenase 155 324 9.8E-46 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 PIRSF PIRSF036497 1 332 2.0E-83 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TAM4_378 cda7fc7e58faadce8366d1e5af3ae355 332 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 200 222 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TAM4_790 d36593b750dd67fe06e90631f0641815 277 PIRSF PIRSF006250 2 276 2.3E-91 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TAM4_790 d36593b750dd67fe06e90631f0641815 277 Gene3D G3DSA:3.90.1170.20 9 271 4.1E-89 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TAM4_790 d36593b750dd67fe06e90631f0641815 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 1.3E-30 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TAM4_790 d36593b750dd67fe06e90631f0641815 277 SUPERFAMILY SSF54675 5 103 1.37E-30 T 23-10-2018 TAM4_790 d36593b750dd67fe06e90631f0641815 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 1.0E-48 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TAM4_790 d36593b750dd67fe06e90631f0641815 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 7.0E-97 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TAM4_790 d36593b750dd67fe06e90631f0641815 277 SUPERFAMILY SSF51690 104 272 3.06E-47 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TAM4_790 d36593b750dd67fe06e90631f0641815 277 Gene3D G3DSA:3.20.20.70 120 263 4.1E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Gene3D G3DSA:3.30.565.10 1 231 5.9E-67 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 SMART SM00387 31 181 1.6E-8 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 549 31.691 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 SUPERFAMILY SSF55874 18 228 7.07E-26 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 130 3.2E-11 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 SUPERFAMILY SSF54211 352 513 2.05E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Gene3D G3DSA:3.30.230.10 352 559 7.8E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Pfam PF09239 Topoisomerase VI B subunit, transducer 353 506 4.1E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 PIRSF PIRSF006553 1 559 2.3E-212 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 532 3.7E-229 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 Gene3D G3DSA:1.10.8.50 232 309 9.1E-10 T 23-10-2018 TAM4_1494 02fb533f2d89e3f5860a1eee93e67ab7 560 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 352 549 1.0E-107 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 SUPERFAMILY SSF54893 3 98 1.57E-33 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 148 2.8E-63 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 4.0E-42 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 95 1.2E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 8.5E-21 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 SUPERFAMILY SSF57825 100 148 8.89E-17 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 Gene3D G3DSA:3.30.70.140 1 97 3.8E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 Gene3D G3DSA:2.30.30.20 98 148 4.2E-23 T 23-10-2018 TAM4_2425 e8c36d9d9efb4c4a46ee0d8d287beb70 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.321 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 PIRSF PIRSF002133 19 147 2.4E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 45.158 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea TAM4_1725 f64a8c6094d8dcc91932544bb04145ea 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 23-10-2018 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 Pfam PF01907 Ribosomal protein L37e 3 56 1.7E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 4.0E-17 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 Gene3D G3DSA:2.20.25.30 1 57 2.2E-20 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.897 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 SUPERFAMILY SSF57829 1 56 2.01E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_1599 7d8a986679e791e2892744ad09b03c40 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 Pfam PF13173 AAA domain 50 173 5.8E-26 T 23-10-2018 TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 Gene3D G3DSA:3.40.50.300 23 163 3.6E-6 T 23-10-2018 TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 SMART SM00382 46 161 5.2E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 SUPERFAMILY SSF52540 47 178 1.11E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 Gene3D G3DSA:1.10.10.10 247 305 1.5E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 SUPERFAMILY SSF46785 251 302 9.33E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1907 10136d01389af3c8c0c782eb57e10cba 435 Pfam PF09339 IclR helix-turn-helix domain 249 299 1.7E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TAM4_476 c9e3bd20d82e886d5f74240ff73f76f4 142 SUPERFAMILY SSF53146 1 112 2.62E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_476 c9e3bd20d82e886d5f74240ff73f76f4 142 Gene3D G3DSA:3.30.420.130 1 115 3.7E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_476 c9e3bd20d82e886d5f74240ff73f76f4 142 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 3.2E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TAM4_339 0b1679252207f49f2de60642e7a7143a 418 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 350 379 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site TAM4_339 0b1679252207f49f2de60642e7a7143a 418 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 401 411 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TAM4_339 0b1679252207f49f2de60642e7a7143a 418 Gene3D G3DSA:2.40.50.140 2 62 2.7E-15 T 23-10-2018 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 411 9.4E-70 T 23-10-2018 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 Gene3D G3DSA:3.40.1350.30 113 261 1.5E-96 T 23-10-2018 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 344 418 2.0E-15 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 SUPERFAMILY SSF50249 4 59 3.14E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_339 0b1679252207f49f2de60642e7a7143a 418 Pfam PF02475 Met-10+ like-protein 273 331 3.2E-9 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 Gene3D G3DSA:3.40.50.150 74 413 1.5E-96 T 23-10-2018 TAM4_339 0b1679252207f49f2de60642e7a7143a 418 SUPERFAMILY SSF53335 61 418 5.19E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 SUPERFAMILY SSF56784 19 243 5.12E-49 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 206 2.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 Gene3D G3DSA:1.10.150.520 34 112 1.0E-84 T 23-10-2018 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 Gene3D G3DSA:3.40.50.1000 21 237 1.0E-84 T 23-10-2018 IPR023214 HAD superfamily TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 171 7.5E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 193 7.5E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 20 31 7.5E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 137 7.5E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 103 213 6.5E-14 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 109 211 6.9E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 19 238 6.2E-84 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TAM4_1924 d2a9ab388ba7b44246bc0f0ba2abd3d5 260 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 211 7.6E-33 T 23-10-2018 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 13 129 7.5E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 PIRSF PIRSF002131 2 136 3.6E-35 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 SUPERFAMILY SSF53137 9 135 3.14E-39 T 23-10-2018 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 Pfam PF00411 Ribosomal protein S11 15 133 1.6E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 Gene3D G3DSA:3.30.420.80 1 137 5.9E-65 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 9 134 23.633 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TAM4_324 5e13c1f48b7d994b7e2ddcbee6b6951b 137 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 SUPERFAMILY SSF50104 6 116 4.3E-40 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 119 2.9E-36 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 Pfam PF00467 KOW motif 48 79 1.4E-10 T 23-10-2018 IPR005824 KOW TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.303 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 SMART SM00739 45 72 2.8E-7 T 23-10-2018 IPR005824 KOW TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 Gene3D G3DSA:2.30.30.30 2 121 5.4E-54 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_63 209b389ed17bb9c27508e749cf3e9d55 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 2.4E-59 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1557 df3e35af4f597e882a39317306e74369 182 Gene3D G3DSA:3.40.50.300 1 182 7.6E-53 T 23-10-2018 TAM4_1557 df3e35af4f597e882a39317306e74369 182 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.357 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TAM4_1557 df3e35af4f597e882a39317306e74369 182 SUPERFAMILY SSF52540 2 180 1.03E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1557 df3e35af4f597e882a39317306e74369 182 Pfam PF01926 50S ribosome-binding GTPase 2 129 1.2E-18 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1557 df3e35af4f597e882a39317306e74369 182 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 5.2E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 PIRSF PIRSF029271 3 335 1.1E-147 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 Gene3D G3DSA:3.20.20.70 1 316 3.9E-153 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 3.4E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 2.5E-145 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 52.991 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 SUPERFAMILY SSF51366 24 310 1.08E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 Pfam PF01680 SOR/SNZ family 13 213 1.5E-94 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_735 f06f106418ab78cc470f5b6d75847a4b 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TAM4_538 a941cfa55f90cb80ab97d6fb99bc9f7a 130 Gene3D G3DSA:2.40.10.310 61 130 1.3E-32 T 23-10-2018 TAM4_538 a941cfa55f90cb80ab97d6fb99bc9f7a 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_538 a941cfa55f90cb80ab97d6fb99bc9f7a 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.317 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_538 a941cfa55f90cb80ab97d6fb99bc9f7a 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 9.8E-48 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_538 a941cfa55f90cb80ab97d6fb99bc9f7a 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.8E-33 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 TAM4_1571 c3b0c7ca2187de9d5f81326dc9efc5dd 148 SUPERFAMILY SSF46785 57 128 1.59E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1571 c3b0c7ca2187de9d5f81326dc9efc5dd 148 Gene3D G3DSA:1.10.10.10 55 132 1.0E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1660 b2b1da1d9db4794a67afef649f07493c 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 4.1E-21 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TAM4_1660 b2b1da1d9db4794a67afef649f07493c 281 SMART SM00518 4 276 6.1E-90 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TAM4_1660 b2b1da1d9db4794a67afef649f07493c 281 SUPERFAMILY SSF51658 7 278 2.9E-63 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TAM4_1660 b2b1da1d9db4794a67afef649f07493c 281 Gene3D G3DSA:3.20.20.150 13 281 9.8E-43 T 23-10-2018 TAM4_91 a5093395431b95d44571438ebee79ea9 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 TAM4_91 a5093395431b95d44571438ebee79ea9 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 7.6E-58 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.772 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 Gene3D G3DSA:3.30.1330.30 1 123 1.5E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_91 a5093395431b95d44571438ebee79ea9 123 SUPERFAMILY SSF55315 4 121 2.06E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TAM4_91 a5093395431b95d44571438ebee79ea9 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 2.1E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 5.3E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 5.3E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 5.3E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 5.3E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_91 a5093395431b95d44571438ebee79ea9 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 5.3E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1368 1386e8b79844077957c2359edde21a18 291 SUPERFAMILY SSF52402 12 147 9.21E-25 T 23-10-2018 TAM4_1368 1386e8b79844077957c2359edde21a18 291 Gene3D G3DSA:3.40.50.620 9 154 5.4E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1368 1386e8b79844077957c2359edde21a18 291 PRINTS PR01438 Universal stress protein signature 267 289 3.4E-17 T 23-10-2018 IPR006015 Universal stress protein A TAM4_1368 1386e8b79844077957c2359edde21a18 291 PRINTS PR01438 Universal stress protein signature 249 261 3.4E-17 T 23-10-2018 IPR006015 Universal stress protein A TAM4_1368 1386e8b79844077957c2359edde21a18 291 PRINTS PR01438 Universal stress protein signature 12 30 3.4E-17 T 23-10-2018 IPR006015 Universal stress protein A TAM4_1368 1386e8b79844077957c2359edde21a18 291 Pfam PF00582 Universal stress protein family 206 289 1.3E-15 T 23-10-2018 IPR006016 UspA TAM4_1368 1386e8b79844077957c2359edde21a18 291 Pfam PF00582 Universal stress protein family 11 145 4.7E-20 T 23-10-2018 IPR006016 UspA TAM4_1368 1386e8b79844077957c2359edde21a18 291 Gene3D G3DSA:3.40.50.620 161 291 1.2E-23 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1368 1386e8b79844077957c2359edde21a18 291 SUPERFAMILY SSF52402 164 289 4.1E-21 T 23-10-2018 TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 SUPERFAMILY SSF46785 238 313 3.85E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 Pfam PF01637 ATPase domain predominantly from Archaea 2 195 1.0E-18 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 Gene3D G3DSA:3.40.50.300 73 164 3.4E-15 T 23-10-2018 TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 Gene3D G3DSA:3.40.50.300 1 72 3.2E-11 T 23-10-2018 TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 Pfam PF03008 Archaea bacterial proteins of unknown function 305 400 3.7E-30 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_140 e8cad1a5131c338383ca42bd3398ffe3 447 SUPERFAMILY SSF52540 1 235 1.49E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 SUPERFAMILY SSF55031 156 259 4.78E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 Gene3D G3DSA:3.40.630.10 14 336 1.1E-59 T 23-10-2018 TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 Gene3D G3DSA:3.30.70.360 155 264 1.1E-59 T 23-10-2018 TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 SUPERFAMILY SSF53187 7 345 3.14E-41 T 23-10-2018 TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 Pfam PF07687 Peptidase dimerisation domain 152 258 1.2E-9 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TAM4_1545 2445d496a700985ce9114ebc7aeb7a63 354 Pfam PF01546 Peptidase family M20/M25/M40 64 343 3.2E-24 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TAM4_362 08a3507b8ef3c9437d222e3dde7d30b0 249 Gene3D G3DSA:3.40.50.300 1 245 1.9E-60 T 23-10-2018 TAM4_362 08a3507b8ef3c9437d222e3dde7d30b0 249 Pfam PF03029 Conserved hypothetical ATP binding protein 6 242 2.6E-54 T 23-10-2018 IPR004130 GPN-loop GTPase TAM4_362 08a3507b8ef3c9437d222e3dde7d30b0 249 SUPERFAMILY SSF52540 1 237 2.36E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 SUPERFAMILY SSF53706 3 576 1.57E-187 T 23-10-2018 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 SMART SM00926 3 58 1.3E-14 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 58 1.1E-11 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 432 449 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Gene3D G3DSA:2.20.25.90 4 58 6.9E-14 T 23-10-2018 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Pfam PF00384 Molybdopterin oxidoreductase 61 486 1.6E-93 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 SUPERFAMILY SSF50692 541 682 4.4E-45 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Gene3D G3DSA:3.40.50.740 73 532 7.9E-158 T 23-10-2018 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Gene3D G3DSA:2.40.40.20 562 685 3.7E-41 T 23-10-2018 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Gene3D G3DSA:3.40.228.10 142 341 7.9E-158 T 23-10-2018 TAM4_1110 b196780e26fbec7b7e81802f6f7c460b 685 Pfam PF01568 Molydopterin dinucleotide binding domain 574 676 6.3E-32 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TAM4_940 055b8e5cb29a5d9eb71eaed598e62d8c 181 Pfam PF06195 Protein of unknown function (DUF996) 1 151 2.4E-26 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Pfam PF01380 SIS domain 457 584 1.3E-23 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Pfam PF01380 SIS domain 284 412 1.8E-32 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TAM4_485 402f055b77b20fce60edc2a351a68530 602 SUPERFAMILY SSF53697 247 602 1.11E-111 T 23-10-2018 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Gene3D G3DSA:3.60.20.10 2 240 2.4E-80 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_485 402f055b77b20fce60edc2a351a68530 602 Gene3D G3DSA:3.40.50.10490 442 587 4.2E-138 T 23-10-2018 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Gene3D G3DSA:3.40.50.10490 251 601 4.2E-138 T 23-10-2018 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 41.631 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TAM4_485 402f055b77b20fce60edc2a351a68530 602 Pfam PF13522 Glutamine amidotransferase domain 64 186 7.2E-23 T 23-10-2018 TAM4_485 402f055b77b20fce60edc2a351a68530 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 1.6E-250 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TAM4_485 402f055b77b20fce60edc2a351a68530 602 SUPERFAMILY SSF56235 2 228 1.89E-76 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 Pfam PF03008 Archaea bacterial proteins of unknown function 295 389 1.5E-10 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 SUPERFAMILY SSF46785 231 341 4.41E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 SUPERFAMILY SSF52540 1 193 1.46E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 Gene3D G3DSA:3.40.50.300 57 150 6.7E-11 T 23-10-2018 TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 Pfam PF13173 AAA domain 18 155 1.4E-11 T 23-10-2018 TAM4_760 fb4e8dff92f566edd33a394e17e73abb 447 Gene3D G3DSA:1.10.10.10 225 297 6.3E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 Gene3D G3DSA:1.10.569.10 237 428 8.3E-93 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 Gene3D G3DSA:1.10.599.10 235 597 8.3E-93 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 SUPERFAMILY SSF48310 207 601 7.59E-105 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 SUPERFAMILY SSF56228 1 203 9.81E-68 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 2.1E-69 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 217 597 3.1E-100 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 Gene3D G3DSA:3.60.9.10 1 206 3.5E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_573 7dd20a022b8b56292008bc69dcf0be48 621 SMART SM00790 4 204 1.5E-114 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 Gene3D G3DSA:3.90.1150.10 19 439 1.6E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 SUPERFAMILY SSF53383 34 444 2.39E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 Pfam PF00202 Aminotransferase class-III 37 443 1.6E-102 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 Gene3D G3DSA:3.40.640.10 73 344 1.6E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 PIRSF PIRSF000521 138 446 8.5E-35 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1225 bdb8e190ded166318a02aaf70e07009f 459 PIRSF PIRSF000521 2 142 3.5E-12 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1655 6dfe4e0ce65b5412ccb4b2326d53b545 241 SUPERFAMILY SSF50249 134 224 1.49E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1655 6dfe4e0ce65b5412ccb4b2326d53b545 241 Gene3D G3DSA:1.20.1440.150 1 124 1.5E-59 T 23-10-2018 TAM4_1655 6dfe4e0ce65b5412ccb4b2326d53b545 241 Gene3D G3DSA:2.40.50.140 125 241 1.3E-35 T 23-10-2018 TAM4_1655 6dfe4e0ce65b5412ccb4b2326d53b545 241 Pfam PF01588 Putative tRNA binding domain 138 224 1.3E-18 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 SUPERFAMILY SSF51445 112 369 4.12E-48 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 TIGRFAM TIGR01370 TIGR01370: extracellular protein 91 380 2.0E-119 T 23-10-2018 IPR016063 Extracellular protein TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 Pfam PF03537 Glycoside-hydrolase family GH114 114 375 1.3E-32 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 Gene3D G3DSA:3.20.20.70 102 391 1.9E-113 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 275 289 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 357 369 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 161 180 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 184 201 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 221 240 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 115 128 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 256 268 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 330 340 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 129 142 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_911 eec0042c574bc12a6c88e4cd173ced70 392 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 203 221 3.0E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TAM4_1337 f2c9639d2e9875b852c9b76f71086849 319 Gene3D G3DSA:2.60.120.180 29 292 7.9E-73 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TAM4_1337 f2c9639d2e9875b852c9b76f71086849 319 Pfam PF01670 Glycosyl hydrolase family 12 55 276 5.0E-37 T 23-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 TAM4_1337 f2c9639d2e9875b852c9b76f71086849 319 SUPERFAMILY SSF49899 55 283 5.88E-40 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TAM4_1892 30c11d2ad76d31288b2a88f3d216abb5 115 Pfam PF01880 Desulfoferrodoxin 9 111 1.1E-32 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TAM4_1892 30c11d2ad76d31288b2a88f3d216abb5 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 2.3E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TAM4_1892 30c11d2ad76d31288b2a88f3d216abb5 115 SUPERFAMILY SSF49367 2 114 2.22E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TAM4_1892 30c11d2ad76d31288b2a88f3d216abb5 115 Gene3D G3DSA:2.60.40.730 1 115 4.0E-52 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 PIRSF PIRSF002116 2 243 2.4E-101 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Gene3D G3DSA:2.40.50.740 123 178 2.8E-17 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Pfam PF00900 Ribosomal family S4e 96 173 1.6E-23 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 SUPERFAMILY SSF55174 52 96 1.7E-7 T 23-10-2018 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 43.394 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 SMART SM00363 44 107 1.2E-9 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 2.6E-17 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Gene3D G3DSA:2.30.30.30 179 243 7.3E-19 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Gene3D G3DSA:3.10.290.40 1 118 4.2E-50 T 23-10-2018 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 9.0E-41 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_73 206c2dce497ee7efc6ae0a6f1909402e 243 Pfam PF01479 S4 domain 45 91 3.4E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2070 fc7e26299b80e6f5c0aa63343df90f16 256 Gene3D G3DSA:3.40.50.300 2 252 1.9E-69 T 23-10-2018 TAM4_2070 fc7e26299b80e6f5c0aa63343df90f16 256 SMART SM00382 25 213 4.0E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2070 fc7e26299b80e6f5c0aa63343df90f16 256 SUPERFAMILY SSF52540 2 226 1.41E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2070 fc7e26299b80e6f5c0aa63343df90f16 256 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_2070 fc7e26299b80e6f5c0aa63343df90f16 256 Pfam PF00005 ABC transporter 17 165 2.7E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 Gene3D G3DSA:3.90.1150.10 15 438 1.8E-153 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 SUPERFAMILY SSF53383 34 441 9.85E-129 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 PIRSF PIRSF000521 2 142 1.7E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 PIRSF PIRSF000521 136 443 1.4E-53 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 Pfam PF00202 Aminotransferase class-III 34 440 3.3E-118 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 Gene3D G3DSA:3.40.640.10 72 340 1.8E-153 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1269 e3c6b7bc2e977a7df17190e02e6d7427 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TAM4_872 919431cf9aebd08ef80d7781054c7969 575 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 24.868 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TAM4_872 919431cf9aebd08ef80d7781054c7969 575 Gene3D G3DSA:3.40.50.300 339 545 1.3E-19 T 23-10-2018 TAM4_872 919431cf9aebd08ef80d7781054c7969 575 SUPERFAMILY SSF52540 382 554 1.94E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_872 919431cf9aebd08ef80d7781054c7969 575 PIRSF PIRSF029254 1 575 1.5E-186 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TAM4_872 919431cf9aebd08ef80d7781054c7969 575 SMART SM00534 386 574 2.2E-21 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TAM4_159 2d88766192bc1b805870a31c975bf75d 418 SMART SM00382 33 157 2.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_159 2d88766192bc1b805870a31c975bf75d 418 SUPERFAMILY SSF52540 22 234 9.27E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_159 2d88766192bc1b805870a31c975bf75d 418 Gene3D G3DSA:3.40.50.300 15 165 6.7E-7 T 23-10-2018 TAM4_159 2d88766192bc1b805870a31c975bf75d 418 Pfam PF13173 AAA domain 35 164 8.4E-38 T 23-10-2018 TAM4_159 2d88766192bc1b805870a31c975bf75d 418 Pfam PF13635 Domain of unknown function (DUF4143) 220 355 3.0E-7 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.357 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 2.1E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 SUPERFAMILY SSF56726 81 384 2.09E-79 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 1.1E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 1.1E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 1.1E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 1.1E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 1.1E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 Gene3D G3DSA:1.10.10.10 12 155 8.6E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 Gene3D G3DSA:3.40.1360.10 156 385 1.0E-64 T 23-10-2018 TAM4_1667 dde7523e3ab9ece04ec3d6031e0cb4db 386 Pfam PF04406 Type IIB DNA topoisomerase 83 152 1.2E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 TAM4_1081 becfaf7181c950ed2816ba2bdb190666 243 SUPERFAMILY SSF52540 2 222 1.21E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1081 becfaf7181c950ed2816ba2bdb190666 243 Gene3D G3DSA:3.40.50.300 1 228 1.9E-55 T 23-10-2018 TAM4_1081 becfaf7181c950ed2816ba2bdb190666 243 SMART SM00382 26 223 5.5E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1081 becfaf7181c950ed2816ba2bdb190666 243 Pfam PF00005 ABC transporter 17 160 8.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1081 becfaf7181c950ed2816ba2bdb190666 243 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_340 decfe1064d01b23241446e2d008bb346 183 PIRSF PIRSF002161 2 180 1.2E-54 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_340 decfe1064d01b23241446e2d008bb346 183 SUPERFAMILY SSF55282 15 179 2.35E-57 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_340 decfe1064d01b23241446e2d008bb346 183 Gene3D G3DSA:3.30.1440.10 10 181 5.0E-72 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_340 decfe1064d01b23241446e2d008bb346 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 41.796 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_340 decfe1064d01b23241446e2d008bb346 183 Pfam PF00281 Ribosomal protein L5 16 68 9.3E-20 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_340 decfe1064d01b23241446e2d008bb346 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 8.1E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_515 c448dda52d44533dcf0071c140872d3f 401 Gene3D G3DSA:3.40.50.300 117 395 1.6E-87 T 23-10-2018 TAM4_515 c448dda52d44533dcf0071c140872d3f 401 ProSitePatterns PS00674 AAA-protein family signature. 258 277 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_515 c448dda52d44533dcf0071c140872d3f 401 Pfam PF09336 Vps4 C terminal oligomerisation domain 357 399 8.1E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TAM4_515 c448dda52d44533dcf0071c140872d3f 401 SMART SM00382 151 288 1.2E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_515 c448dda52d44533dcf0071c140872d3f 401 SUPERFAMILY SSF52540 118 398 1.46E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_515 c448dda52d44533dcf0071c140872d3f 401 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 155 286 4.9E-39 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_515 c448dda52d44533dcf0071c140872d3f 401 Gene3D G3DSA:1.10.8.60 287 379 1.6E-87 T 23-10-2018 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 70 336 8.7E-90 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 Pfam PF01189 16S rRNA methyltransferase RsmB/F 134 335 8.9E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 40 130 4.3E-20 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 Gene3D G3DSA:3.30.70.3130 26 129 5.0E-36 T 23-10-2018 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 210 221 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 211 223 1.6E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 319 336 1.6E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 116 130 1.6E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 145 155 1.6E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 261 277 1.6E-29 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 SUPERFAMILY SSF53335 35 336 5.22E-77 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1963 d4adc6d4510b280979932b4d0718afd1 337 Gene3D G3DSA:3.40.50.150 131 337 2.3E-69 T 23-10-2018 TAM4_311 9711ab8a87a338845f64e3b0939ca009 93 Gene3D G3DSA:3.30.460.10 1 90 3.1E-25 T 23-10-2018 TAM4_311 9711ab8a87a338845f64e3b0939ca009 93 Pfam PF01909 Nucleotidyltransferase domain 9 86 4.6E-17 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_311 9711ab8a87a338845f64e3b0939ca009 93 SUPERFAMILY SSF81301 2 90 4.91E-24 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Hamap MF_01264 CCA-adding enzyme [cca]. 1 454 159.323 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Gene3D G3DSA:3.30.70.1550 359 398 7.5E-24 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 SUPERFAMILY SSF81301 1 150 9.81E-36 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Pfam PF01909 Nucleotidyltransferase domain 37 141 5.6E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 278 5.3E-39 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Gene3D G3DSA:1.10.1410.30 9 278 7.9E-87 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 PIRSF PIRSF005335 1 453 3.2E-150 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 6 417 3.6E-141 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Gene3D G3DSA:3.30.70.590 290 426 7.5E-24 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 SUPERFAMILY SSF55003 265 448 1.14E-38 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 SUPERFAMILY SSF81631 153 279 1.65E-36 T 23-10-2018 TAM4_1025 ed54c9f6e68957edd59745b29fb06390 454 Gene3D G3DSA:3.30.460.10 16 152 7.9E-87 T 23-10-2018 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 30 239 2.2E-57 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Gene3D G3DSA:3.40.449.10 27 246 2.6E-148 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Gene3D G3DSA:2.170.8.10 65 398 2.6E-148 T 23-10-2018 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Gene3D G3DSA:3.90.228.20 247 605 2.6E-148 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 606 4.7E-107 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 SUPERFAMILY SSF53795 244 606 1.17E-107 T 23-10-2018 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 SUPERFAMILY SSF68923 13 243 3.3E-62 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 PIRSF PIRSF001348 5 610 2.3E-210 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 607 36.489 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TAM4_1562 0af4a299f1da5008897836444cd0657b 625 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TAM4_2193 d7a8bef668b18bcd265bbb9663982af3 112 SUPERFAMILY SSF46950 8 111 5.62E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TAM4_2193 d7a8bef668b18bcd265bbb9663982af3 112 Gene3D G3DSA:1.10.8.140 31 112 1.2E-26 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TAM4_2193 d7a8bef668b18bcd265bbb9663982af3 112 PIRSF PIRSF015730 1 112 4.7E-35 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TAM4_2193 d7a8bef668b18bcd265bbb9663982af3 112 Pfam PF01984 Double-stranded DNA-binding domain 8 110 1.3E-26 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TAM4_2193 d7a8bef668b18bcd265bbb9663982af3 112 Hamap MF_00026 DNA-binding protein . 3 112 16.099 T 23-10-2018 IPR022889 DNA-binding protein, archaeal TAM4_1455 c104ae17ea640329bc49d07ba70eb9fc 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 215 1.5E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1455 c104ae17ea640329bc49d07ba70eb9fc 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 110 1.7E-23 T 23-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TAM4_1455 c104ae17ea640329bc49d07ba70eb9fc 225 SUPERFAMILY SSF161098 9 207 3.14E-42 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1455 c104ae17ea640329bc49d07ba70eb9fc 225 Gene3D G3DSA:1.10.3720.10 2 216 2.2E-49 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_18 4dc5ef2ecb807696ceb039539ae609ce 393 Pfam PF13699 Domain of unknown function (DUF4157) 104 149 3.2E-5 T 23-10-2018 IPR025295 Domain of unknown function DUF4157 TAM4_1145 74f2afd31eacc1655028e3e8ab985d1f 201 Gene3D G3DSA:3.30.70.3270 32 179 3.1E-21 T 23-10-2018 TAM4_1145 74f2afd31eacc1655028e3e8ab985d1f 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1145 74f2afd31eacc1655028e3e8ab985d1f 201 SUPERFAMILY SSF54862 37 133 2.36E-24 T 23-10-2018 TAM4_1145 74f2afd31eacc1655028e3e8ab985d1f 201 Pfam PF12838 4Fe-4S dicluster domain 53 103 1.5E-14 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1145 74f2afd31eacc1655028e3e8ab985d1f 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 PIRSF PIRSF005285 5 168 1.7E-68 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 SUPERFAMILY SSF55267 3 74 7.06E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 TIGRFAM TIGR00324 endA: tRNA-intron lyase 6 165 3.1E-41 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 2 168 34.173 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 Gene3D G3DSA:3.40.1350.10 76 168 6.3E-34 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 4 67 9.4E-21 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 77 160 2.5E-32 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 SUPERFAMILY SSF53032 77 166 6.93E-31 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TAM4_257 2403707d57c9c0871ff2d6d0d429fca4 168 Gene3D G3DSA:3.40.1170.20 5 70 5.5E-18 T 23-10-2018 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 SUPERFAMILY SSF50249 29 108 6.85E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_347 d7267a4049b04981dede0a96be19cf95 114 Gene3D G3DSA:2.40.50.1000 1 112 8.4E-38 T 23-10-2018 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 7.7E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 3.2E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 3.2E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 3.2E-10 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.159 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 Pfam PF00366 Ribosomal protein S17 35 102 1.9E-25 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_347 d7267a4049b04981dede0a96be19cf95 114 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 99 6.0E-19 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Pfam PF00437 Type II/IV secretion system protein 276 510 1.6E-55 T 23-10-2018 IPR001482 Type II/IV secretion system protein TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SMART SM00382 405 636 9.4E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1333 c384937349b8957578be442bd51c62c1 1194 PRINTS PR00379 Intein signature 824 839 4.1E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 PRINTS PR00379 Intein signature 596 609 4.1E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 PRINTS PR00379 Intein signature 796 808 4.1E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 PRINTS PR00379 Intein signature 1007 1024 4.1E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 PRINTS PR00379 Intein signature 699 711 4.1E-18 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:2.170.16.10 511 655 1.3E-28 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 516 609 2.6E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:3.30.450.380 160 372 1.7E-64 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Pfam PF14890 Intein splicing domain 516 1030 4.8E-30 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SMART SM00305 986 1036 5.1E-17 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Pfam PF14528 LAGLIDADG-like domain 795 872 1.4E-13 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:3.10.28.10 782 894 2.4E-25 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SUPERFAMILY SSF55608 781 888 4.82E-21 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:3.40.50.300 1029 1182 4.4E-35 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:3.40.50.300 373 510 9.2E-60 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1009 1031 4.2E-10 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SUPERFAMILY SSF52540 258 514 1.06E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SMART SM00306 507 633 9.8E-22 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 Gene3D G3DSA:2.170.16.10 955 1028 3.1E-13 T 23-10-2018 TAM4_1333 c384937349b8957578be442bd51c62c1 1194 SUPERFAMILY SSF51294 510 1030 6.54E-37 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1132 52f9261308b5c8b86f9a81358faba0ca 158 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 61 2.2E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_1132 52f9261308b5c8b86f9a81358faba0ca 158 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 5 155 33.473 T 23-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TAM4_1132 52f9261308b5c8b86f9a81358faba0ca 158 Pfam PF01467 Cytidylyltransferase-like 8 144 1.4E-14 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_1132 52f9261308b5c8b86f9a81358faba0ca 158 Gene3D G3DSA:3.40.50.620 5 153 1.0E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1132 52f9261308b5c8b86f9a81358faba0ca 158 SUPERFAMILY SSF52374 2 145 1.69E-20 T 23-10-2018 TAM4_1987 e3b1e030341d4242177ee775e20bd80b 202 Gene3D G3DSA:3.40.50.300 1 202 4.5E-49 T 23-10-2018 TAM4_1987 e3b1e030341d4242177ee775e20bd80b 202 Pfam PF00005 ABC transporter 20 148 1.4E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1987 e3b1e030341d4242177ee775e20bd80b 202 SMART SM00382 29 202 7.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1987 e3b1e030341d4242177ee775e20bd80b 202 SUPERFAMILY SSF52540 5 200 1.1E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1214 16a365cf5e5cdec403ecde08131fd1d9 141 Gene3D G3DSA:3.90.1170.40 1 136 3.6E-52 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TAM4_1214 16a365cf5e5cdec403ecde08131fd1d9 141 SUPERFAMILY SSF54690 3 138 2.62E-48 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TAM4_1214 16a365cf5e5cdec403ecde08131fd1d9 141 Pfam PF02391 MoaE protein 5 117 1.3E-39 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 Gene3D G3DSA:3.40.50.300 3 221 1.5E-69 T 23-10-2018 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 Gene3D G3DSA:2.40.50.940 222 281 7.8E-12 T 23-10-2018 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 SUPERFAMILY SSF50331 237 350 4.54E-12 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 Pfam PF00005 ABC transporter 19 161 4.2E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 Pfam PF08402 TOBE domain 275 349 1.9E-5 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 SUPERFAMILY SSF52540 4 244 8.92E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 SMART SM00382 28 211 2.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1958 754bd39eb00d8c4002fdc817e979919b 353 Gene3D G3DSA:2.40.50.140 282 329 7.8E-12 T 23-10-2018 TAM4_745 ca045d885f279a20951daf3b96b8ecf7 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 15 410 1.2E-126 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_745 ca045d885f279a20951daf3b96b8ecf7 464 Pfam PF01554 MatE 239 405 2.3E-34 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_745 ca045d885f279a20951daf3b96b8ecf7 464 Pfam PF01554 MatE 15 175 1.0E-39 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_745 ca045d885f279a20951daf3b96b8ecf7 464 PIRSF PIRSF006603 1 464 7.9E-109 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_2392 88111e4d7f46c75a5b7a2b73c9017e96 401 SUPERFAMILY SSF111283 29 393 1.24E-53 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_2392 88111e4d7f46c75a5b7a2b73c9017e96 401 Pfam PF01523 Putative modulator of DNA gyrase 5 267 2.0E-20 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 Pfam PF07670 Nucleoside recognition 351 445 3.0E-14 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 Pfam PF07670 Nucleoside recognition 511 630 2.1E-26 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 2.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 2.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 Pfam PF07664 Ferrous iron transport protein B C terminus 455 505 4.5E-16 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 156 7.5E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 Gene3D G3DSA:3.40.50.300 2 189 4.8E-49 T 23-10-2018 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 627 2.0E-184 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 Pfam PF02421 Ferrous iron transport protein B 3 158 1.8E-66 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TAM4_2101 1def725ad39a8416de005a15d7d023bc 660 SUPERFAMILY SSF52540 4 172 2.15E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1871 8856d05e33580695f39e5087407ccd42 113 Gene3D G3DSA:2.60.120.10 9 105 2.1E-22 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TAM4_1871 8856d05e33580695f39e5087407ccd42 113 SUPERFAMILY SSF51182 10 104 1.11E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TAM4_1871 8856d05e33580695f39e5087407ccd42 113 Pfam PF07883 Cupin domain 32 100 4.3E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 3.4E-11 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 3.4E-11 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.4E-11 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.4E-11 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 Pfam PF02080 TrkA-C domain 153 221 1.3E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 SUPERFAMILY SSF116726 139 222 1.44E-15 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 Gene3D G3DSA:3.40.50.720 1 138 6.1E-40 T 23-10-2018 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 Gene3D G3DSA:3.30.70.1450 140 222 3.0E-17 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 SUPERFAMILY SSF51735 1 145 1.92E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1113 7e201befe67927b155d6e763c6e0ca4a 228 Pfam PF02254 TrkA-N domain 3 112 4.8E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TAM4_851 aa9289538cf163564e6843853b0fe5e0 142 Pfam PF04009 Protein of unknown function (DUF356) 5 110 8.8E-35 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TAM4_851 aa9289538cf163564e6843853b0fe5e0 142 PIRSF PIRSF006606 3 135 3.1E-44 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Gene3D G3DSA:3.40.50.740 58 516 2.3E-169 T 23-10-2018 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 4 656 4.3E-267 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 47 5.4E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Gene3D G3DSA:2.40.40.20 540 662 8.5E-36 T 23-10-2018 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 SMART SM00926 1 49 3.0E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Gene3D G3DSA:3.40.228.10 129 326 2.3E-169 T 23-10-2018 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Pfam PF00384 Molybdopterin oxidoreductase 52 472 1.1E-85 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Pfam PF01568 Molydopterin dinucleotide binding domain 553 650 4.0E-24 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 SUPERFAMILY SSF53706 2 554 1.31E-196 T 23-10-2018 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 Gene3D G3DSA:2.20.25.90 1 50 1.0E-9 T 23-10-2018 TAM4_610 fdff7bb5c038949827e2e6d0719fffc1 663 SUPERFAMILY SSF50692 524 658 9.37E-38 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Gene3D G3DSA:2.60.40.1190 1040 1278 1.2E-63 T 23-10-2018 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Gene3D G3DSA:2.60.40.1190 795 1036 1.0E-64 T 23-10-2018 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Pfam PF03065 Glycosyl hydrolase family 57 41 543 3.6E-124 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1042 1271 8.8E-75 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 798 1030 3.3E-76 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 SUPERFAMILY SSF88713 37 582 5.87E-67 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 SUPERFAMILY SSF49344 797 1032 8.63E-78 T 23-10-2018 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 SUPERFAMILY SSF49344 1041 1273 4.71E-76 T 23-10-2018 TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1357 1376 1.0E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_432 051cedd07ba853846b0f0f2a41dd4757 1377 Gene3D G3DSA:3.20.110.20 223 525 2.4E-26 T 23-10-2018 TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 SUPERFAMILY SSF100950 3 309 1.97E-100 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 Gene3D G3DSA:1.20.120.420 1 112 1.9E-45 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 3 297 9.8E-97 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 4 310 9.8E-150 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 Pfam PF01008 Initiation factor 2 subunit family 16 297 3.8E-93 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TAM4_1574 688bd94ff95f1879fc6486d882fad949 320 Gene3D G3DSA:3.40.50.10470 113 308 3.5E-84 T 23-10-2018 TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 8 209 2.2E-76 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 Gene3D G3DSA:3.30.420.10 6 165 3.5E-57 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 Hamap MF_00052_A Ribonuclease HII [rnhB]. 6 210 37.995 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 SUPERFAMILY SSF53098 7 212 1.02E-59 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 Pfam PF01351 Ribonuclease HII 8 205 3.3E-51 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain TAM4_1895 e5cce62eddba75124747d9897f2d385b 230 Gene3D G3DSA:1.10.10.460 166 212 2.1E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 SUPERFAMILY SSF53633 5 228 4.84E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 Gene3D G3DSA:3.40.1160.10 4 229 2.1E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 Pfam PF00696 Amino acid kinase family 5 206 2.9E-33 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 Hamap MF_01220_A Uridylate kinase [pyrH]. 5 229 35.119 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 PIRSF PIRSF005650 1 229 6.8E-60 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TAM4_1249 0d8c32d62eecb773416573fb6f23f19c 229 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 7 228 3.0E-86 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TAM4_1774 b52741109dd74bd73a58cb5a14185168 129 Pfam PF01850 PIN domain 1 114 1.5E-13 T 23-10-2018 IPR002716 PIN domain TAM4_1774 b52741109dd74bd73a58cb5a14185168 129 SUPERFAMILY SSF88723 1 126 6.73E-30 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1774 b52741109dd74bd73a58cb5a14185168 129 Gene3D G3DSA:3.40.50.1010 1 128 1.1E-26 T 23-10-2018 TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 Gene3D G3DSA:3.40.50.300 19 350 3.1E-113 T 23-10-2018 TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 Gene3D G3DSA:1.10.8.60 355 439 7.7E-26 T 23-10-2018 TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 Pfam PF06068 TIP49 C-terminus 15 404 2.0E-160 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 SMART SM00382 63 354 1.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 Gene3D G3DSA:2.40.50.360 120 244 3.1E-113 T 23-10-2018 TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 SUPERFAMILY SSF50249 127 208 1.01E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1834 ef18b846014ed913f106b5f1ca5aab81 441 SUPERFAMILY SSF52540 37 424 3.7E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1476 ba79b43c4ceee1e3f568a7d2efcd1cd0 306 Pfam PF01112 Asparaginase 3 298 8.1E-94 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 TAM4_1476 ba79b43c4ceee1e3f568a7d2efcd1cd0 306 SUPERFAMILY SSF56235 18 298 1.23E-86 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_1476 ba79b43c4ceee1e3f568a7d2efcd1cd0 306 Gene3D G3DSA:3.60.20.30 176 303 1.8E-33 T 23-10-2018 TAM4_2401 08693a7689d5002a5b6616c3fa77e293 68 SUPERFAMILY SSF141694 2 61 2.35E-13 T 23-10-2018 TAM4_2401 08693a7689d5002a5b6616c3fa77e293 68 Gene3D G3DSA:4.10.1150.10 1 65 8.2E-12 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_2401 08693a7689d5002a5b6616c3fa77e293 68 Pfam PF01954 Protein of unknown function DUF104 2 55 9.1E-16 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_1833 85cc1529c58cd482f89d521bef303814 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 2.9E-92 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1833 85cc1529c58cd482f89d521bef303814 311 Gene3D G3DSA:3.30.70.3130 7 96 4.1E-17 T 23-10-2018 TAM4_1833 85cc1529c58cd482f89d521bef303814 311 Gene3D G3DSA:3.40.50.150 101 311 2.3E-72 T 23-10-2018 TAM4_1833 85cc1529c58cd482f89d521bef303814 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 14 97 8.6E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TAM4_1833 85cc1529c58cd482f89d521bef303814 311 SUPERFAMILY SSF53335 22 306 7.9E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 2.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 2.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 2.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 2.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 2.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1833 85cc1529c58cd482f89d521bef303814 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 1.5E-53 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 Gene3D G3DSA:3.90.650.10 143 324 1.4E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 137 1.1E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 300 1.4E-23 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 SUPERFAMILY SSF56042 142 311 4.49E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 SUPERFAMILY SSF55326 4 140 5.58E-26 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 PIRSF PIRSF005644 1 324 5.5E-85 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TAM4_2039 7456967044861aaf10ba34eb3fa0cba1 324 Gene3D G3DSA:3.30.1330.10 2 138 9.9E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_803 ce42017dc76fa45ebe5307e90d90a248 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 2.0E-114 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 TAM4_803 ce42017dc76fa45ebe5307e90d90a248 222 Hamap MF_00264 UPF0128 protein . 1 222 135.83 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 TAM4_803 ce42017dc76fa45ebe5307e90d90a248 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 3.5E-98 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 TAM4_803 ce42017dc76fa45ebe5307e90d90a248 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 1.2E-106 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 TAM4_1634 26640e894b9384c6bcb1ee36e00072ca 323 SUPERFAMILY SSF53686 35 319 3.4E-55 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TAM4_1634 26640e894b9384c6bcb1ee36e00072ca 323 Gene3D G3DSA:3.40.50.1100 63 160 5.0E-55 T 23-10-2018 TAM4_1634 26640e894b9384c6bcb1ee36e00072ca 323 PIRSF PIRSF006278 64 321 8.8E-9 T 23-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase TAM4_1634 26640e894b9384c6bcb1ee36e00072ca 323 Gene3D G3DSA:3.40.50.1100 34 318 5.0E-55 T 23-10-2018 TAM4_1634 26640e894b9384c6bcb1ee36e00072ca 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 318 9.2E-54 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TAM4_1170 1a1ee90ff01868535acf4f6fa5681c37 98 SUPERFAMILY SSF46785 2 96 8.88E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1170 1a1ee90ff01868535acf4f6fa5681c37 98 Pfam PF13601 Winged helix DNA-binding domain 17 94 5.1E-22 T 23-10-2018 IPR027395 Winged helix DNA-binding domain TAM4_1170 1a1ee90ff01868535acf4f6fa5681c37 98 SMART SM00418 8 93 0.0013 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1170 1a1ee90ff01868535acf4f6fa5681c37 98 Gene3D G3DSA:1.10.10.10 1 98 1.7E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1450 1218103376b464d0d632966e34799a66 439 Gene3D G3DSA:3.50.50.60 107 431 2.3E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1450 1218103376b464d0d632966e34799a66 439 Gene3D G3DSA:3.50.50.60 2 331 2.3E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1450 1218103376b464d0d632966e34799a66 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 3.0E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.8E-22 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.8E-22 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.8E-22 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.8E-22 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.8E-22 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 1.2E-68 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_1450 1218103376b464d0d632966e34799a66 439 SUPERFAMILY SSF51905 142 307 1.86E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1450 1218103376b464d0d632966e34799a66 439 SUPERFAMILY SSF51905 1 191 5.05E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 6.3E-17 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 6.3E-17 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.3E-17 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 6.3E-17 T 23-10-2018 TAM4_1450 1218103376b464d0d632966e34799a66 439 SUPERFAMILY SSF55424 316 438 1.37E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SUPERFAMILY SSF52540 541 818 1.16E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:1.10.8.60 715 822 1.0E-30 T 23-10-2018 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:3.40.50.300 203 378 2.5E-74 T 23-10-2018 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SMART SM01073 14 98 1.7E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SUPERFAMILY SSF50692 11 96 4.85E-26 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SMART SM01072 116 200 3.2E-16 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SUPERFAMILY SSF52540 206 531 3.93E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 ProSitePatterns PS00674 AAA-protein family signature. 684 702 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SUPERFAMILY SSF54585 98 213 1.44E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SMART SM00382 579 716 8.2E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 SMART SM00382 244 380 4.0E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:1.10.8.60 443 534 3.3E-16 T 23-10-2018 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:3.40.50.300 535 714 2.0E-73 T 23-10-2018 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 200 5.5E-14 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 1.8E-29 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 824 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 5.3E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 583 713 3.1E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:2.40.40.20 7 98 8.8E-33 T 23-10-2018 TAM4_1541 d43ef7e28e727cc769ed08e3d0ef5bfb 838 Gene3D G3DSA:1.10.8.60 379 442 2.0E-6 T 23-10-2018 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Gene3D G3DSA:1.10.150.190 86 171 3.9E-34 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 SUPERFAMILY SSF110993 176 260 5.36E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 SUPERFAMILY SSF50249 7 87 6.58E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Gene3D G3DSA:3.30.70.1130 173 262 3.5E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 5.5E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Pfam PF00575 S1 RNA binding domain 9 83 1.5E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 SUPERFAMILY SSF116742 85 174 2.49E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Gene3D G3DSA:2.40.50.140 3 85 1.4E-31 T 23-10-2018 TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.972 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal TAM4_893 ae537688a31ea1aba36d2cbad631ae82 273 SMART SM00316 10 83 4.6E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 TAM4_301 67b26220bddb8b4217a3b90ab4567b13 151 SUPERFAMILY SSF52402 4 151 4.19E-26 T 23-10-2018 TAM4_301 67b26220bddb8b4217a3b90ab4567b13 151 Pfam PF00582 Universal stress protein family 4 151 9.5E-21 T 23-10-2018 IPR006016 UspA TAM4_301 67b26220bddb8b4217a3b90ab4567b13 151 Gene3D G3DSA:3.40.50.620 1 151 5.1E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_301 67b26220bddb8b4217a3b90ab4567b13 151 PRINTS PR01438 Universal stress protein signature 129 151 4.4E-5 T 23-10-2018 IPR006015 Universal stress protein A TAM4_301 67b26220bddb8b4217a3b90ab4567b13 151 PRINTS PR01438 Universal stress protein signature 2 20 4.4E-5 T 23-10-2018 IPR006015 Universal stress protein A TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 Gene3D G3DSA:3.90.650.10 156 338 9.6E-58 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 314 3.3E-32 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 PIRSF PIRSF005644 1 338 8.3E-125 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 SUPERFAMILY SSF55326 6 155 5.76E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 4.7E-120 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 SUPERFAMILY SSF56042 157 332 3.59E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 Gene3D G3DSA:3.30.1330.10 1 155 2.3E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_1133 2d643352acf92241e1be5ba8805e68b8 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 1.6E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 SUPERFAMILY SSF51735 1 150 5.91E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 174 295 3.2E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 1.6E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 Gene3D G3DSA:3.40.50.720 1 171 4.2E-65 T 23-10-2018 TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 SUPERFAMILY SSF48179 174 295 1.05E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 Gene3D G3DSA:1.10.1040.10 172 296 2.4E-41 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TAM4_1233 c48024053a0bf2d84456d59c89061d61 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 7.0E-38 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TAM4_1215 11ac044f51d6ae9b167fe5274eecf4c6 275 Pfam PF00892 EamA-like transporter family 6 129 1.1E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1215 11ac044f51d6ae9b167fe5274eecf4c6 275 Pfam PF00892 EamA-like transporter family 144 271 2.6E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1215 11ac044f51d6ae9b167fe5274eecf4c6 275 SUPERFAMILY SSF103481 193 271 2.22E-9 T 23-10-2018 TAM4_1215 11ac044f51d6ae9b167fe5274eecf4c6 275 SUPERFAMILY SSF103481 37 133 6.8E-10 T 23-10-2018 TAM4_1085 1c550df287437ce260e8349a2865a519 261 Gene3D G3DSA:3.40.50.12640 1 261 1.0E-119 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily TAM4_1085 1c550df287437ce260e8349a2865a519 261 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 67 240 1.0E-73 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TAM4_1085 1c550df287437ce260e8349a2865a519 261 PIRSF PIRSF004853 1 254 2.4E-110 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TAM4_1085 1c550df287437ce260e8349a2865a519 261 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 252 1.0E-89 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 108 329 4.4E-41 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 5 386 3.7E-169 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 SUPERFAMILY SSF88697 503 577 4.42E-21 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 SUPERFAMILY SSF51713 1 354 1.7E-116 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 356 425 4.4E-41 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Pfam PF01472 PUA domain 505 576 7.1E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 SUPERFAMILY SSF88802 356 501 1.24E-41 T 23-10-2018 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Gene3D G3DSA:2.30.130.10 501 578 6.7E-33 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Gene3D G3DSA:3.90.1020.10 356 425 9.5E-28 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 SMART SM00359 504 578 1.0E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Gene3D G3DSA:3.20.20.105 1 355 1.9E-124 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 336 4.2E-88 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 435 502 3.1E-21 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Gene3D G3DSA:3.10.450.90 426 500 1.4E-26 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 487 574 1.5E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_2111 13d309dd5095803d07c11e308186a5a5 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 5 530 48.398 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 SMART SM00863 702 745 2.7E-18 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Gene3D G3DSA:3.30.54.20 675 726 1.4E-29 T 23-10-2018 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 SUPERFAMILY SSF50447 512 597 7.77E-19 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Gene3D G3DSA:3.30.980.10 605 674 1.0E-21 T 23-10-2018 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Pfam PF01411 tRNA synthetases class II (A) 61 603 9.5E-163 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Pfam PF02272 DHHA1 domain 782 911 1.3E-20 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 702 744 8.4E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Gene3D G3DSA:3.10.310.40 813 913 1.1E-20 T 23-10-2018 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 909 24.153 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 SUPERFAMILY SSF55681 57 264 1.02E-57 T 23-10-2018 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Gene3D G3DSA:3.30.930.10 2 260 7.0E-115 T 23-10-2018 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 911 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 SUPERFAMILY SSF55186 603 752 2.49E-48 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 3.3E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 3.3E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 3.3E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 3.3E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 3.3E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 893 6.7E-236 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 SUPERFAMILY SSF101353 306 501 1.57E-50 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TAM4_1389 54aca3a44a7d99bedcd06bf69cd0915e 913 Gene3D G3DSA:2.40.30.130 502 599 2.0E-36 T 23-10-2018 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 2.0E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 2.0E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 2.0E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 2.0E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 2.0E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 SUPERFAMILY SSF52954 504 606 1.21E-32 T 23-10-2018 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Gene3D G3DSA:3.50.80.10 1 139 2.7E-57 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.236 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 1.0E-60 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 6.4E-56 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 289 492 5.5E-19 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 SUPERFAMILY SSF55681 207 489 1.38E-57 T 23-10-2018 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 26 603 7.8E-174 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Pfam PF03129 Anticodon binding domain 513 602 8.9E-26 T 23-10-2018 IPR004154 Anticodon-binding TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Gene3D G3DSA:3.30.930.10 203 494 5.0E-62 T 23-10-2018 TAM4_713 b3804c4735a524c99917c4d7073e7790 626 Gene3D G3DSA:3.40.50.800 504 608 5.7E-35 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TAM4_42 07f28b8cc7488f21fa08e09a3e9f4fe9 268 Gene3D G3DSA:3.40.1350.10 138 248 1.7E-5 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 Pfam PF00708 Acylphosphatase 7 88 7.5E-29 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 PRINTS PR00112 Acylphosphatase signature 5 20 1.6E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 PRINTS PR00112 Acylphosphatase signature 26 51 1.6E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 SUPERFAMILY SSF54975 2 90 3.05E-32 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1231 9c0b572b84c1dd4b46b92d5f70a5e9d7 91 Gene3D G3DSA:3.30.70.100 1 91 6.2E-39 T 23-10-2018 TAM4_737 d3c5fbf39356b5e870ee409807195444 240 Pfam PF01522 Polysaccharide deacetylase 4 128 2.8E-15 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TAM4_737 d3c5fbf39356b5e870ee409807195444 240 Gene3D G3DSA:3.20.20.370 3 238 5.4E-36 T 23-10-2018 TAM4_737 d3c5fbf39356b5e870ee409807195444 240 SUPERFAMILY SSF88713 4 235 1.83E-28 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 Pfam PF00005 ABC transporter 26 182 8.3E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 SUPERFAMILY SSF52540 33 312 4.13E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.8E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 Gene3D G3DSA:3.40.50.300 3 319 4.6E-103 T 23-10-2018 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.4E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_1126 4d4639f15796204d8f8dc28dc9e86557 319 SMART SM00382 34 240 5.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 SUPERFAMILY SSF47323 707 912 4.49E-39 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Gene3D G3DSA:1.10.10.720 864 915 2.6E-47 T 23-10-2018 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Gene3D G3DSA:3.30.2320.20 833 965 2.6E-47 T 23-10-2018 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 SUPERFAMILY SSF52374 1 693 6.61E-100 T 23-10-2018 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Gene3D G3DSA:3.90.740.10 204 450 1.5E-301 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Gene3D G3DSA:3.40.50.620 8 687 1.5E-301 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 11 688 9.5E-67 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Gene3D G3DSA:1.10.730.10 689 808 6.8E-33 T 23-10-2018 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 SUPERFAMILY SSF50677 209 442 5.65E-34 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 5 965 18.367 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 Pfam PF08264 Anticodon-binding domain of tRNA 724 855 1.8E-29 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TAM4_153 0a24fa00f039d64eaa38d72ff3ba408e 965 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 7 965 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_48 9577e3a2577cb00f785833432105dddd 469 Pfam PF03008 Archaea bacterial proteins of unknown function 322 413 8.1E-20 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_48 9577e3a2577cb00f785833432105dddd 469 Gene3D G3DSA:3.40.50.300 1 172 1.0E-32 T 23-10-2018 TAM4_48 9577e3a2577cb00f785833432105dddd 469 SUPERFAMILY SSF52540 1 213 1.1E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_48 9577e3a2577cb00f785833432105dddd 469 Pfam PF01637 ATPase domain predominantly from Archaea 2 210 2.3E-24 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 PIRSF PIRSF039085 4 248 3.2E-99 T 23-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 SUPERFAMILY SSF52540 8 242 2.59E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 SMART SM00382 32 220 2.3E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 Gene3D G3DSA:3.40.50.300 5 251 5.2E-81 T 23-10-2018 TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 Pfam PF00005 ABC transporter 23 172 1.3E-39 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1155 dcfa54fad998dc0c4f22e5c0d0cd1892 254 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1762 1f854e25326ee427ca39af875884e472 328 SMART SM00962 130 325 2.4E-112 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 SMART SM00382 129 281 2.6E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1762 1f854e25326ee427ca39af875884e472 328 Gene3D G3DSA:3.40.50.300 116 324 3.6E-86 T 23-10-2018 TAM4_1762 1f854e25326ee427ca39af875884e472 328 SUPERFAMILY SSF52540 122 325 2.05E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1762 1f854e25326ee427ca39af875884e472 328 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 51 324 1.6E-108 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TAM4_1762 1f854e25326ee427ca39af875884e472 328 Pfam PF02881 SRP54-type protein, helical bundle domain 45 105 7.0E-11 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 50 325 57.695 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TAM4_1762 1f854e25326ee427ca39af875884e472 328 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 298 311 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 Pfam PF00448 SRP54-type protein, GTPase domain 131 324 1.7E-78 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 SUPERFAMILY SSF47364 43 113 1.09E-13 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 SMART SM00963 38 111 1.3E-6 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TAM4_1762 1f854e25326ee427ca39af875884e472 328 Gene3D G3DSA:1.20.120.140 2 113 1.5E-25 T 23-10-2018 TAM4_1441 cfddb6077b89a113ecf96ffe898b7492 100 Gene3D G3DSA:3.30.70.1340 1 86 5.2E-35 T 23-10-2018 IPR023129 MTH889-like domain superfamily TAM4_1441 cfddb6077b89a113ecf96ffe898b7492 100 SUPERFAMILY SSF160363 4 93 4.97E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily TAM4_1441 cfddb6077b89a113ecf96ffe898b7492 100 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 4.0E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TAM4_1441 cfddb6077b89a113ecf96ffe898b7492 100 Pfam PF02680 Uncharacterized ArCR, COG1888 5 91 5.0E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 150 252 1.3E-35 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 Gene3D G3DSA:1.10.3730.10 153 254 2.2E-36 T 23-10-2018 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 SUPERFAMILY SSF48179 149 256 1.41E-34 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 PIRSF PIRSF000193 1 257 1.3E-69 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 252 1.8E-78 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 Gene3D G3DSA:3.40.50.720 1 152 8.6E-44 T 23-10-2018 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 SUPERFAMILY SSF51735 1 148 4.45E-32 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 254 25.816 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TAM4_1500 86205989aa3d30cdc38d824ecd2626dc 258 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 91 7.1E-21 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TAM4_1485 0bde311df685bb06d8fa5378f29aefb4 276 Pfam PF01040 UbiA prenyltransferase family 23 256 1.1E-44 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TAM4_1485 0bde311df685bb06d8fa5378f29aefb4 276 Gene3D G3DSA:1.20.120.1780 158 276 2.1E-5 T 23-10-2018 TAM4_1485 0bde311df685bb06d8fa5378f29aefb4 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.591 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 TAM4_1485 0bde311df685bb06d8fa5378f29aefb4 276 Gene3D G3DSA:1.10.357.140 10 156 7.2E-14 T 23-10-2018 TAM4_2347 0630fb316a96be0519456bba45dc9e25 189 SUPERFAMILY SSF51182 3 188 2.67E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TAM4_2347 0630fb316a96be0519456bba45dc9e25 189 Hamap MF_01410 Glucose-6-phosphate isomerase [pgiA]. 2 185 46.161 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TAM4_2347 0630fb316a96be0519456bba45dc9e25 189 Gene3D G3DSA:2.60.120.10 1 189 4.0E-75 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TAM4_2347 0630fb316a96be0519456bba45dc9e25 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 179 2.8E-41 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TAM4_2347 0630fb316a96be0519456bba45dc9e25 189 PIRSF PIRSF019325 1 189 1.2E-75 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TAM4_1127 c2fd237c6d73d58c3d4abe2a41f2cd0a 315 Gene3D G3DSA:1.10.8.300 200 309 7.1E-37 T 23-10-2018 TAM4_1127 c2fd237c6d73d58c3d4abe2a41f2cd0a 315 SUPERFAMILY SSF52540 12 284 2.15E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1127 c2fd237c6d73d58c3d4abe2a41f2cd0a 315 PIRSF PIRSF002849 1 314 1.5E-140 T 23-10-2018 TAM4_1127 c2fd237c6d73d58c3d4abe2a41f2cd0a 315 Gene3D G3DSA:3.40.50.300 19 185 2.3E-49 T 23-10-2018 TAM4_1127 c2fd237c6d73d58c3d4abe2a41f2cd0a 315 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 38 168 1.7E-68 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 SUPERFAMILY SSF53901 11 169 2.07E-33 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 10 170 1.2E-4 T 23-10-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 Gene3D G3DSA:3.40.47.10 8 348 1.9E-73 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 349 5.0E-193 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 SUPERFAMILY SSF53901 174 348 3.03E-46 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 3.4E-11 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TAM4_592 bcc77cc9d6af05cb68fc950c7904457c 350 Hamap MF_01409 UPF0219 protein . 10 350 61.353 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TAM4_2127 df82af11d580897ef848591230b994a3 233 SMART SM00418 7 88 1.5E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_2127 df82af11d580897ef848591230b994a3 233 Pfam PF12840 Helix-turn-helix domain 7 61 3.6E-8 T 23-10-2018 TAM4_2127 df82af11d580897ef848591230b994a3 233 Gene3D G3DSA:1.10.10.10 4 79 3.9E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2127 df82af11d580897ef848591230b994a3 233 Gene3D G3DSA:1.10.10.10 161 229 7.6E-37 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2127 df82af11d580897ef848591230b994a3 233 SUPERFAMILY SSF46785 146 193 8.17E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2127 df82af11d580897ef848591230b994a3 233 SUPERFAMILY SSF46785 1 145 8.79E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2398 6b01bb7a1f498c42dbe15e37e12c941b 136 SUPERFAMILY SSF88723 1 123 7.29E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2398 6b01bb7a1f498c42dbe15e37e12c941b 136 Pfam PF01850 PIN domain 4 125 2.9E-14 T 23-10-2018 IPR002716 PIN domain TAM4_2398 6b01bb7a1f498c42dbe15e37e12c941b 136 SMART SM00670 1 122 8.6E-10 T 23-10-2018 IPR002716 PIN domain TAM4_2398 6b01bb7a1f498c42dbe15e37e12c941b 136 Gene3D G3DSA:3.40.50.1010 3 135 1.4E-11 T 23-10-2018 TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 SUPERFAMILY SSF55031 166 269 1.15E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 Pfam PF01546 Peptidase family M20/M25/M40 61 365 8.9E-26 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 Pfam PF07687 Peptidase dimerisation domain 164 265 8.7E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 Gene3D G3DSA:3.40.630.10 5 357 1.9E-69 T 23-10-2018 TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 SUPERFAMILY SSF53187 3 366 1.8E-51 T 23-10-2018 TAM4_1135 ded7f27f86389e30c139053f6f38a4a9 386 Gene3D G3DSA:3.30.70.360 172 280 1.9E-69 T 23-10-2018 TAM4_1984 1faf41685c2a806c561397d01c4dfb64 136 Gene3D G3DSA:3.30.110.60 5 111 5.6E-22 T 23-10-2018 IPR035920 YhbY-like superfamily TAM4_1984 1faf41685c2a806c561397d01c4dfb64 136 SMART SM01103 5 92 1.8E-27 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TAM4_1984 1faf41685c2a806c561397d01c4dfb64 136 SUPERFAMILY SSF75471 5 100 8.5E-19 T 23-10-2018 IPR035920 YhbY-like superfamily TAM4_1984 1faf41685c2a806c561397d01c4dfb64 136 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 1.1E-13 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TAM4_1984 1faf41685c2a806c561397d01c4dfb64 136 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 7.0E-40 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 Gene3D G3DSA:3.40.50.300 1 247 2.6E-82 T 23-10-2018 TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 Pfam PF06745 KaiC 5 237 3.2E-93 T 23-10-2018 IPR014774 KaiC-like domain TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 SUPERFAMILY SSF52540 3 236 8.5E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 Hamap MF_01076 UPF0273 protein . 2 245 63.395 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 PRINTS PR01874 DNA repair protein radA signature 14 42 1.1E-8 T 23-10-2018 TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 PRINTS PR01874 DNA repair protein radA signature 56 73 1.1E-8 T 23-10-2018 TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 PRINTS PR01874 DNA repair protein radA signature 167 195 1.1E-8 T 23-10-2018 TAM4_1230 e9cc640823ea73de2e5488f73b82b24f 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 6.2E-142 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 292 310 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 67 77 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 228 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 160 184 4.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 SUPERFAMILY SSF51905 7 333 3.71E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 302 8.7E-31 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 Gene3D G3DSA:3.50.50.60 10 302 1.0E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.9E-25 T 23-10-2018 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 4.9E-25 T 23-10-2018 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 4.9E-25 T 23-10-2018 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 4.9E-25 T 23-10-2018 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 4.9E-25 T 23-10-2018 TAM4_131 36cf3a68100a8ba7a2bcde5bf0895ca3 418 Gene3D G3DSA:3.50.50.60 129 262 1.0E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 5.0E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 SUPERFAMILY SSF53649 4 404 3.32E-45 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 Pfam PF01676 Metalloenzyme superfamily 5 400 2.2E-56 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 PIRSF PIRSF006392 1 407 2.6E-156 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 9.5E-139 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 Gene3D G3DSA:3.30.70.2130 81 230 5.6E-144 T 23-10-2018 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 46.04 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TAM4_869 4fa69c8f09b7835e6821e0a42ceeb0d2 411 Gene3D G3DSA:3.40.720.10 7 397 5.6E-144 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TAM4_1974 0e48093d3404961d2d3e593b7ee864a2 321 SMART SM00028 81 114 33.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1974 0e48093d3404961d2d3e593b7ee864a2 321 SMART SM00028 121 154 0.19 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_1974 0e48093d3404961d2d3e593b7ee864a2 321 Pfam PF10602 26S proteasome subunit RPN7 82 189 1.1E-7 T 23-10-2018 IPR019585 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 Reactome: R-HSA-8951664 TAM4_1974 0e48093d3404961d2d3e593b7ee864a2 321 Gene3D G3DSA:1.25.40.10 51 228 4.6E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1974 0e48093d3404961d2d3e593b7ee864a2 321 SUPERFAMILY SSF48452 80 220 3.03E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 60 553 6.8E-168 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 SUPERFAMILY SSF56091 222 425 2.64E-55 T 23-10-2018 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Hamap MF_00407 DNA ligase [lig]. 4 553 34.599 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Pfam PF04675 DNA ligase N terminus 6 179 3.7E-39 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 250 258 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Gene3D G3DSA:1.10.3260.10 2 223 7.7E-86 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Pfam PF04679 ATP dependent DNA ligase C terminal region 446 537 3.4E-21 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Pfam PF01068 ATP dependent DNA ligase domain 227 425 1.3E-65 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 401 425 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 SUPERFAMILY SSF117018 3 244 4.97E-70 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Gene3D G3DSA:2.40.50.140 426 562 1.2E-53 T 23-10-2018 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 Gene3D G3DSA:3.30.470.30 224 425 1.6E-75 T 23-10-2018 TAM4_1751 87faaf537c6e4a79aa40a39cbca9cc8c 562 SUPERFAMILY SSF50249 429 555 3.66E-41 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_633 d23730f0b00a568240014bfc3ad00942 143 Gene3D G3DSA:1.20.120.1630 5 142 5.6E-24 T 23-10-2018 TAM4_633 d23730f0b00a568240014bfc3ad00942 143 Pfam PF04191 Phospholipid methyltransferase 63 127 1.1E-4 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Pfam PF00069 Protein kinase domain 767 1007 2.7E-49 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 SUPERFAMILY SSF56112 755 1010 8.09E-67 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 SMART SM00220 767 1013 9.4E-62 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 773 795 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 877 889 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Gene3D G3DSA:2.60.40.1120 7 102 4.3E-6 T 23-10-2018 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Gene3D G3DSA:2.60.40.1120 177 240 5.3E-5 T 23-10-2018 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Pfam PF08308 PEGA domain 36 103 2.1E-20 T 23-10-2018 IPR013229 PEGA TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Pfam PF08308 PEGA domain 106 171 1.7E-18 T 23-10-2018 IPR013229 PEGA TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Pfam PF08308 PEGA domain 175 239 6.3E-22 T 23-10-2018 IPR013229 PEGA TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Gene3D G3DSA:1.10.510.10 754 1029 9.9E-66 T 23-10-2018 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 SUPERFAMILY SSF48452 385 612 3.8E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_499 d8591b1d4ab55c688b4eb3e52a1997fb 1114 Gene3D G3DSA:1.25.40.10 418 654 1.0E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 78 177 4.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 Gene3D G3DSA:3.90.550.10 202 436 2.6E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 Gene3D G3DSA:3.40.50.1000 1 193 2.0E-34 T 23-10-2018 IPR023214 HAD superfamily TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 SUPERFAMILY SSF56784 1 217 2.94E-41 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 Pfam PF00535 Glycosyl transferase family 2 221 342 2.8E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 SUPERFAMILY SSF53448 219 423 4.35E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_423 7f88ab897f7392d9db6e9098e868977a 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 183 1.3E-27 T 23-10-2018 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 Gene3D G3DSA:1.20.5.620 18 98 7.1E-25 T 23-10-2018 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 197 14.913 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 Gene3D G3DSA:3.30.2320.30 100 197 2.2E-21 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 196 3.1E-35 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 SUPERFAMILY SSF160527 81 197 3.27E-26 T 23-10-2018 TAM4_1195 b41edb849eadc9763f4fc09eded3dc0c 197 SUPERFAMILY SSF81573 23 82 2.94E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TAM4_157 01c9739f51246353544bf5dfab912c82 343 Gene3D G3DSA:3.40.50.11030 215 343 1.6E-37 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily TAM4_157 01c9739f51246353544bf5dfab912c82 343 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 206 2.8E-67 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TAM4_157 01c9739f51246353544bf5dfab912c82 343 SUPERFAMILY SSF55821 13 208 5.8E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TAM4_157 01c9739f51246353544bf5dfab912c82 343 Pfam PF01300 Telomere recombination 21 196 1.3E-59 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TAM4_157 01c9739f51246353544bf5dfab912c82 343 Gene3D G3DSA:3.90.870.10 2 212 3.5E-86 T 23-10-2018 TAM4_157 01c9739f51246353544bf5dfab912c82 343 PIRSF PIRSF004930 2 339 3.8E-128 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 TAM4_157 01c9739f51246353544bf5dfab912c82 343 Pfam PF03481 Putative GTP-binding controlling metal-binding 201 333 8.7E-27 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 PIRSF PIRSF003092 1 258 1.5E-65 T 23-10-2018 IPR025501 ATP binding protein MinD TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 2.1E-118 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 SMART SM00382 3 163 0.0033 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 SUPERFAMILY SSF52540 3 236 3.09E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 Gene3D G3DSA:3.40.50.300 4 233 3.7E-67 T 23-10-2018 TAM4_222 9632e9e92247751c64ea13a9a47a1a17 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 8.0E-25 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_1508 251d46f3c5726eaa3c90b0f942dd2350 304 Pfam PF00288 GHMP kinases N terminal domain 93 151 5.7E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TAM4_1508 251d46f3c5726eaa3c90b0f942dd2350 304 PIRSF PIRSF016896 1 296 4.7E-92 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 TAM4_1508 251d46f3c5726eaa3c90b0f942dd2350 304 SUPERFAMILY SSF54211 1 157 9.87E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1897 55dee9d973f8037da3a9927f05e53eef 745 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 195 1.5E-19 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TAM4_691 3647e784e3a11a420a600c72f803b4d9 177 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TAM4_691 3647e784e3a11a420a600c72f803b4d9 177 Gene3D G3DSA:3.90.80.10 1 177 8.2E-75 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TAM4_691 3647e784e3a11a420a600c72f803b4d9 177 Pfam PF00719 Inorganic pyrophosphatase 20 171 7.7E-58 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TAM4_691 3647e784e3a11a420a600c72f803b4d9 177 SUPERFAMILY SSF50324 2 172 1.44E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TAM4_691 3647e784e3a11a420a600c72f803b4d9 177 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.481 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Gene3D G3DSA:3.20.70.20 33 291 1.2E-23 T 23-10-2018 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Gene3D G3DSA:3.20.70.20 702 981 1.2E-40 T 23-10-2018 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 643 665 0.0023 T 23-10-2018 IPR030934 Intein C-terminal splicing region TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SMART SM00305 623 670 0.007 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Gene3D G3DSA:3.10.28.10 429 606 3.2E-25 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 PRINTS PR00379 Intein signature 431 443 2.4E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 PRINTS PR00379 Intein signature 362 375 2.4E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 PRINTS PR00379 Intein signature 659 668 2.4E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 PRINTS PR00379 Intein signature 548 560 2.4E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 PRINTS PR00379 Intein signature 640 657 2.4E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SMART SM00306 276 401 2.2E-9 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SUPERFAMILY SSF51294 278 665 9.89E-24 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Pfam PF14890 Intein splicing domain 324 664 7.7E-15 T 23-10-2018 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SUPERFAMILY SSF55608 530 597 1.57E-12 T 23-10-2018 IPR027434 Homing endonuclease TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Gene3D G3DSA:2.170.16.10 312 428 1.6E-7 T 23-10-2018 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 22 278 7.0E-63 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 658 999 3.3E-78 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 278 374 2.2E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SUPERFAMILY SSF51998 651 983 4.88E-62 T 23-10-2018 TAM4_1111 44e546b648ce796007ebbdd35cda6583 1001 SUPERFAMILY SSF51998 23 296 4.88E-59 T 23-10-2018 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Gene3D G3DSA:1.10.730.10 669 853 1.0E-54 T 23-10-2018 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 5.1E-37 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 876 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 SUPERFAMILY SSF52374 2 674 1.66E-136 T 23-10-2018 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 SUPERFAMILY SSF50677 203 401 5.02E-55 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 SUPERFAMILY SSF47323 676 913 1.83E-60 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1066 13.799 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 6.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 6.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 6.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 6.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 6.9E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Gene3D G3DSA:3.40.50.620 16 651 1.4E-232 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 SUPERFAMILY SSF47323 984 1051 1.96E-7 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 663 1.4E-188 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_732 43a3b8dfef34de47ddd6e71b2fb6ab26 1066 Gene3D G3DSA:3.90.740.10 199 405 1.4E-232 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TAM4_1045 bce62a941251b180746a274b6e20a806 656 SUPERFAMILY SSF52540 21 642 5.12E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1045 bce62a941251b180746a274b6e20a806 656 Gene3D G3DSA:3.40.50.300 5 239 1.0E-9 T 23-10-2018 TAM4_1045 bce62a941251b180746a274b6e20a806 656 SUPERFAMILY SSF75712 302 394 4.97E-8 T 23-10-2018 TAM4_1045 bce62a941251b180746a274b6e20a806 656 Pfam PF00769 Ezrin/radixin/moesin family 174 406 1.0E-8 T 23-10-2018 IPR011259 Ezrin/radixin/moesin, C-terminal TAM4_1045 bce62a941251b180746a274b6e20a806 656 Gene3D G3DSA:1.10.287.510 301 402 1.5E-6 T 23-10-2018 TAM4_1045 bce62a941251b180746a274b6e20a806 656 Gene3D G3DSA:3.40.50.300 488 652 3.7E-9 T 23-10-2018 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 Gene3D G3DSA:3.10.20.30 319 397 4.0E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 Gene3D G3DSA:1.10.8.470 126 215 6.5E-33 T 23-10-2018 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 Pfam PF02824 TGS domain 341 393 2.3E-13 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 1.5E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 1.5E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 1.5E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 1.5E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 1.4E-36 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 SUPERFAMILY SSF52540 1 315 1.93E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 SUPERFAMILY SSF81271 322 393 8.24E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TAM4_721 c712849e4ced72b0ec5f3218257c619b 397 Pfam PF01926 50S ribosome-binding GTPase 2 121 2.4E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 Gene3D G3DSA:1.10.10.2700 1 150 1.8E-67 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 Pfam PF01090 Ribosomal protein S19e 3 138 2.1E-59 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 SUPERFAMILY SSF46785 3 150 4.27E-62 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 38.384 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 SMART SM01413 3 139 1.4E-92 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2069 9b2f6782735860671edf0b0a6b157704 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 5.0E-59 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1954 f0d49e862430f0cb34da4a948b205dc1 259 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 198 1.4E-50 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TAM4_1954 f0d49e862430f0cb34da4a948b205dc1 259 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.25 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TAM4_1954 f0d49e862430f0cb34da4a948b205dc1 259 SUPERFAMILY SSF69796 5 198 9.94E-58 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TAM4_1954 f0d49e862430f0cb34da4a948b205dc1 259 Gene3D G3DSA:3.30.1360.170 1 202 1.1E-62 T 23-10-2018 TAM4_1954 f0d49e862430f0cb34da4a948b205dc1 259 Pfam PF02511 Thymidylate synthase complementing protein 8 197 6.7E-61 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TAM4_1054 6ffbdbb6985a147f9cc2de904841b1dc 211 Pfam PF13247 4Fe-4S dicluster domain 62 156 2.3E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1054 6ffbdbb6985a147f9cc2de904841b1dc 211 Pfam PF12837 4Fe-4S binding domain 14 32 1.7E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1054 6ffbdbb6985a147f9cc2de904841b1dc 211 SUPERFAMILY SSF54862 11 170 4.4E-57 T 23-10-2018 TAM4_1054 6ffbdbb6985a147f9cc2de904841b1dc 211 Gene3D G3DSA:3.30.70.20 35 207 2.7E-46 T 23-10-2018 TAM4_1054 6ffbdbb6985a147f9cc2de904841b1dc 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1938 418da48f8a48e4653bd157989a8f6f40 131 PIRSF PIRSF004966 1 131 1.1E-54 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative TAM4_1938 418da48f8a48e4653bd157989a8f6f40 131 Gene3D G3DSA:3.50.30.10 1 130 4.3E-50 T 23-10-2018 TAM4_1938 418da48f8a48e4653bd157989a8f6f40 131 Hamap MF_00078 UPF0107 protein . 2 129 33.544 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative TAM4_1938 418da48f8a48e4653bd157989a8f6f40 131 SUPERFAMILY SSF52016 1 128 1.33E-44 T 23-10-2018 TAM4_1938 418da48f8a48e4653bd157989a8f6f40 131 Pfam PF01989 Protein of unknown function DUF126 24 103 3.0E-36 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Gene3D G3DSA:3.30.565.60 209 366 2.9E-46 T 23-10-2018 IPR038475 RecG, C-terminal domain superfamily TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 280 365 4.4E-21 T 23-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Gene3D G3DSA:1.10.10.10 367 442 6.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Gene3D G3DSA:3.30.950.30 2 129 2.2E-32 T 23-10-2018 IPR038461 Schlafen, AAA domain superfamily TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Pfam PF08220 DeoR-like helix-turn-helix domain 383 431 1.4E-6 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 SUPERFAMILY SSF46785 370 441 1.61E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1010 698516b647583db9be2a51c9b01da6c6 446 Pfam PF04326 Putative DNA-binding domain 11 121 3.9E-22 T 23-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 TAM4_314 2f201ce5762ece85ed7fac98bbd8070d 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site TAM4_314 2f201ce5762ece85ed7fac98bbd8070d 170 Gene3D G3DSA:3.60.21.10 1 159 2.8E-53 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_314 2f201ce5762ece85ed7fac98bbd8070d 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 3.5E-40 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TAM4_314 2f201ce5762ece85ed7fac98bbd8070d 170 SUPERFAMILY SSF56300 1 160 1.08E-40 T 23-10-2018 TAM4_314 2f201ce5762ece85ed7fac98bbd8070d 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 2.4E-33 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TAM4_585 f9cc1adb6872a6a6ed85f41e93eca57c 386 SUPERFAMILY SSF51905 12 376 5.83E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_585 f9cc1adb6872a6a6ed85f41e93eca57c 386 Gene3D G3DSA:3.50.50.60 12 359 1.0E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_585 f9cc1adb6872a6a6ed85f41e93eca57c 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 1.9E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TAM4_585 f9cc1adb6872a6a6ed85f41e93eca57c 386 SUPERFAMILY SSF54373 224 316 7.26E-10 T 23-10-2018 TAM4_585 f9cc1adb6872a6a6ed85f41e93eca57c 386 Gene3D G3DSA:3.30.9.10 88 315 1.0E-140 T 23-10-2018 TAM4_1101 25db8d350f55a19ad12e786814e77e9d 148 SUPERFAMILY SSF52218 1 146 1.97E-22 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_1101 25db8d350f55a19ad12e786814e77e9d 148 Pfam PF12724 Flavodoxin domain 5 125 9.0E-22 T 23-10-2018 IPR026816 Flavodoxin domain TAM4_1101 25db8d350f55a19ad12e786814e77e9d 148 Gene3D G3DSA:3.40.50.360 2 142 2.1E-20 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_1101 25db8d350f55a19ad12e786814e77e9d 148 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 23-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TAM4_2433 ef9e93250ed5a171a3d68048d390a9a1 303 SUPERFAMILY SSF53448 4 218 2.34E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_2433 ef9e93250ed5a171a3d68048d390a9a1 303 Pfam PF00535 Glycosyl transferase family 2 7 166 1.3E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_2433 ef9e93250ed5a171a3d68048d390a9a1 303 Gene3D G3DSA:3.90.550.10 1 234 3.6E-77 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1593 44dd796636a5d2b4fc33e6419f41c70f 234 Pfam PF06745 KaiC 5 229 5.6E-51 T 23-10-2018 IPR014774 KaiC-like domain TAM4_1593 44dd796636a5d2b4fc33e6419f41c70f 234 Gene3D G3DSA:3.40.50.300 1 233 9.3E-60 T 23-10-2018 TAM4_1593 44dd796636a5d2b4fc33e6419f41c70f 234 PRINTS PR01874 DNA repair protein radA signature 56 73 2.7E-9 T 23-10-2018 TAM4_1593 44dd796636a5d2b4fc33e6419f41c70f 234 PRINTS PR01874 DNA repair protein radA signature 14 42 2.7E-9 T 23-10-2018 TAM4_1593 44dd796636a5d2b4fc33e6419f41c70f 234 SUPERFAMILY SSF52540 2 228 1.36E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1683 65688682b7b1b3cf9b49be4db9fda24b 218 Pfam PF01917 Archaebacterial flagellin 4 204 8.7E-50 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_1683 65688682b7b1b3cf9b49be4db9fda24b 218 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 3.2E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TAM4_441 a013bac488faa44106a22280f63b8921 290 Pfam PF01435 Peptidase family M48 68 280 8.6E-37 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TAM4_441 a013bac488faa44106a22280f63b8921 290 Hamap MF_00188 Protease HtpX [htpX]. 6 280 30.33 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TAM4_441 a013bac488faa44106a22280f63b8921 290 Gene3D G3DSA:3.30.2010.10 61 151 1.0E-32 T 23-10-2018 TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 Gene3D G3DSA:3.10.330.20 2 62 2.7E-24 T 23-10-2018 TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 3 47 3.3E-8 T 23-10-2018 TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 PIRSF PIRSF017269 1 254 8.1E-80 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 75 233 3.0E-27 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 SUPERFAMILY SSF53335 2 253 2.07E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_755 5098d4de08bb54a404b7c97e1422c2c6 254 Gene3D G3DSA:3.40.50.150 64 254 1.2E-67 T 23-10-2018 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Pfam PF14520 Helix-hairpin-helix domain 643 696 2.3E-10 T 23-10-2018 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Pfam PF09210 Domain of unknown function (DUF1957) 427 524 4.9E-26 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 SUPERFAMILY SSF88688 415 530 2.91E-31 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Gene3D G3DSA:3.20.110.10 1 415 4.0E-171 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Pfam PF03065 Glycosyl hydrolase family 57 6 368 1.1E-69 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 SUPERFAMILY SSF88713 2 415 7.42E-121 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Gene3D G3DSA:1.20.1430.10 416 560 3.9E-57 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TAM4_1516 c91f46432fed3b3611bdcd5646e29e46 696 Gene3D G3DSA:1.10.150.20 634 696 1.5E-11 T 23-10-2018 TAM4_1819 377adab849fd43035276be52d2f83de9 277 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TAM4_1819 377adab849fd43035276be52d2f83de9 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 7.0E-97 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 TAM4_1819 377adab849fd43035276be52d2f83de9 277 Pfam PF01048 Phosphorylase superfamily 31 256 1.9E-45 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TAM4_1819 377adab849fd43035276be52d2f83de9 277 SUPERFAMILY SSF53167 18 247 1.44E-75 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TAM4_1819 377adab849fd43035276be52d2f83de9 277 Gene3D G3DSA:3.40.50.1580 7 261 3.0E-86 T 23-10-2018 TAM4_1973 b90b34c180b22ec8bbd0b4b1799ece01 154 SUPERFAMILY SSF88723 26 68 9.16E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1973 b90b34c180b22ec8bbd0b4b1799ece01 154 Pfam PF01927 Mut7-C RNAse domain 1 144 8.9E-45 T 23-10-2018 IPR002782 Mut7-C RNAse domain TAM4_1973 b90b34c180b22ec8bbd0b4b1799ece01 154 Gene3D G3DSA:3.40.50.1010 5 72 9.6E-6 T 23-10-2018 TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 PIRSF PIRSF000216 2 154 6.0E-61 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 SUPERFAMILY SSF52833 7 151 3.69E-54 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 9 147 1.2E-43 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 8 147 8.1E-55 T 23-10-2018 TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 Gene3D G3DSA:3.40.30.10 66 153 3.6E-33 T 23-10-2018 TAM4_7 2d65a5d0b92699ca81f0ce76db5bbef9 154 Gene3D G3DSA:1.10.10.1590 2 65 5.2E-20 T 23-10-2018 TAM4_839 4ab27935a62cf13e42bb47f4a16f680d 148 Pfam PF01850 PIN domain 3 124 5.6E-11 T 23-10-2018 IPR002716 PIN domain TAM4_839 4ab27935a62cf13e42bb47f4a16f680d 148 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 130 10.125 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_839 4ab27935a62cf13e42bb47f4a16f680d 148 SMART SM00670 1 121 6.3E-5 T 23-10-2018 IPR002716 PIN domain TAM4_839 4ab27935a62cf13e42bb47f4a16f680d 148 Gene3D G3DSA:3.40.50.1010 1 127 4.3E-13 T 23-10-2018 TAM4_839 4ab27935a62cf13e42bb47f4a16f680d 148 SUPERFAMILY SSF88723 2 131 3.92E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1964 db6b7b284586c21106dcf5bd2459ab72 122 SUPERFAMILY SSF103196 9 121 3.14E-21 T 23-10-2018 TAM4_1964 db6b7b284586c21106dcf5bd2459ab72 122 Pfam PF03259 Roadblock/LC7 domain 12 96 7.9E-14 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain TAM4_1964 db6b7b284586c21106dcf5bd2459ab72 122 Gene3D G3DSA:3.30.450.30 7 122 3.5E-24 T 23-10-2018 TAM4_1964 db6b7b284586c21106dcf5bd2459ab72 122 SMART SM00960 8 97 3.7E-15 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 SUPERFAMILY SSF52540 163 440 7.68E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 55.052 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 3.1E-49 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 SUPERFAMILY SSF50615 1 68 1.39E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Gene3D G3DSA:3.40.50.300 70 434 9.9E-187 T 23-10-2018 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Gene3D G3DSA:2.40.30.20 1 69 1.5E-29 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Gene3D G3DSA:1.10.1140.10 435 585 9.4E-61 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 SMART SM00382 223 411 0.0016 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 6.1E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Gene3D G3DSA:2.40.50.100 113 184 9.9E-187 T 23-10-2018 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 SUPERFAMILY SSF47917 447 552 7.85E-27 T 23-10-2018 TAM4_1338 69ce56d98ad09cf2dfa6a1f641e14f61 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.9E-93 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TAM4_1046 db0439b1f1aaf01007a14d8e5d5b2f72 632 Pfam PF00361 Proton-conducting membrane transporter 132 430 3.1E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1046 db0439b1f1aaf01007a14d8e5d5b2f72 632 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 1.7E-8 T 23-10-2018 TAM4_1046 db0439b1f1aaf01007a14d8e5d5b2f72 632 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 223 244 1.7E-8 T 23-10-2018 TAM4_1046 db0439b1f1aaf01007a14d8e5d5b2f72 632 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 1.7E-8 T 23-10-2018 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 3.0E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 SUPERFAMILY SSF53218 181 325 2.09E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Gene3D G3DSA:2.40.340.10 329 400 1.5E-25 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Gene3D G3DSA:3.90.105.10 26 178 2.3E-112 T 23-10-2018 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 4.0E-31 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 1.3E-44 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Gene3D G3DSA:2.170.190.11 49 145 2.3E-112 T 23-10-2018 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 SUPERFAMILY SSF63867 331 399 2.62E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 SUPERFAMILY SSF63882 6 180 7.85E-56 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 SMART SM00852 184 321 4.4E-37 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 6.7E-26 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_250 6f7ec23b99d14ed4680c3ab7258885a4 400 Gene3D G3DSA:3.40.980.10 179 320 2.3E-112 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_788 547508f394e98d8369cfbc6fb30e4f9a 292 SMART SM00849 15 200 6.8E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_788 547508f394e98d8369cfbc6fb30e4f9a 292 SUPERFAMILY SSF56281 15 272 3.36E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_788 547508f394e98d8369cfbc6fb30e4f9a 292 Gene3D G3DSA:3.60.15.10 9 225 1.1E-29 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_788 547508f394e98d8369cfbc6fb30e4f9a 292 Pfam PF00753 Metallo-beta-lactamase superfamily 16 186 1.5E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1538 9e8d7f7f4bb504538928fa0bc81ece94 204 Pfam PF02517 CAAX protease self-immunity 110 187 1.4E-7 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 Pfam PF01455 HupF/HypC family 1 67 5.4E-24 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 Gene3D G3DSA:2.40.50.970 1 76 8.0E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 76 1.0E-22 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 SUPERFAMILY SSF159127 1 76 3.79E-22 T 23-10-2018 IPR037254 HupF/HypC superfamily TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 5.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 5.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 5.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1161 43921e4fa1e52fe2e25247420a94aa83 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 19 35 5.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 PIRSF PIRSF000915 3 265 1.8E-62 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 Gene3D G3DSA:3.40.50.1000 7 253 7.4E-94 T 23-10-2018 IPR023214 HAD superfamily TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 3.2E-29 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 235 2.9E-46 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 SUPERFAMILY SSF56784 5 259 1.88E-69 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 Pfam PF13242 HAD-hyrolase-like 187 259 3.3E-21 T 23-10-2018 TAM4_1074 a95635da012e2446a29596a8d716a5e3 274 Gene3D G3DSA:3.40.50.1000 71 187 7.4E-94 T 23-10-2018 IPR023214 HAD superfamily TAM4_121 6671f1047162d333cc782c591d20c6fc 372 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 3.9E-51 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TAM4_121 6671f1047162d333cc782c591d20c6fc 372 SUPERFAMILY SSF53649 1 359 1.13E-76 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TAM4_121 6671f1047162d333cc782c591d20c6fc 372 Gene3D G3DSA:3.40.720.10 1 370 1.5E-57 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 58.686 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 SUPERFAMILY SSF54211 3 180 3.42E-45 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 Gene3D G3DSA:3.30.70.890 187 319 1.9E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 2.0E-85 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.7E-29 T 23-10-2018 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.7E-29 T 23-10-2018 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.7E-29 T 23-10-2018 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.7E-29 T 23-10-2018 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 4.5E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 Gene3D G3DSA:3.30.230.10 1 182 1.4E-49 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 Pfam PF08544 GHMP kinases C terminal 244 310 2.0E-14 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TAM4_1835 9de93c6fc5b1a9ac7709707b5757f33e 334 SUPERFAMILY SSF55060 183 329 3.6E-36 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 Gene3D G3DSA:3.30.1370.30 1 69 5.9E-33 T 23-10-2018 TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 Pfam PF00410 Ribosomal protein S8 5 130 6.9E-30 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 SUPERFAMILY SSF56047 3 130 1.83E-40 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 Gene3D G3DSA:3.30.1490.10 70 128 3.2E-27 T 23-10-2018 TAM4_32 46cf7bedaf781a7835eef5ca371f5d89 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.872 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_902 f5765e5d654f08b9690804f5de979779 484 SUPERFAMILY SSF51445 3 482 5.43E-127 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_902 f5765e5d654f08b9690804f5de979779 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 403 3.2E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 445 3.2E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 332 3.2E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 418 3.2E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 452 464 3.2E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 Gene3D G3DSA:3.20.20.80 1 484 2.0E-138 T 23-10-2018 TAM4_902 f5765e5d654f08b9690804f5de979779 484 Pfam PF00232 Glycosyl hydrolase family 1 3 89 5.7E-9 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 Pfam PF00232 Glycosyl hydrolase family 1 123 481 3.1E-54 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TAM4_902 f5765e5d654f08b9690804f5de979779 484 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 395 403 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 Gene3D G3DSA:3.30.70.330 1 98 9.2E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 SUPERFAMILY SSF54189 1 97 6.47E-32 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 4.0E-30 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 Pfam PF01282 Ribosomal protein S24e 21 97 2.0E-26 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_568 248ad06bc92ff45baa150f472bf583a1 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.267 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_939 f749bca0552ac31935afdcd1b243ddbe 194 Gene3D G3DSA:1.20.58.1030 1 113 2.6E-36 T 23-10-2018 TAM4_939 f749bca0552ac31935afdcd1b243ddbe 194 Gene3D G3DSA:3.40.5.50 141 194 2.2E-19 T 23-10-2018 TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 PIRSF PIRSF037724 1 237 5.4E-105 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 Gene3D G3DSA:1.10.260.40 24 80 2.0E-11 T 23-10-2018 TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 SMART SM00530 26 81 3.2E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 Pfam PF12844 Helix-turn-helix domain 27 75 1.7E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 SUPERFAMILY SSF75138 113 221 1.29E-5 T 23-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily TAM4_1049 c7f1d06b266d0b32f1886c9435f3fa17 243 SUPERFAMILY SSF47413 22 75 8.19E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_1550 5e4c010baeafb19dce02dc0f3ec5e9e5 357 Gene3D G3DSA:1.10.8.60 208 285 9.9E-17 T 23-10-2018 TAM4_1550 5e4c010baeafb19dce02dc0f3ec5e9e5 357 SUPERFAMILY SSF52540 9 281 3.13E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1550 5e4c010baeafb19dce02dc0f3ec5e9e5 357 Pfam PF01637 ATPase domain predominantly from Archaea 22 244 2.8E-11 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1550 5e4c010baeafb19dce02dc0f3ec5e9e5 357 Gene3D G3DSA:3.40.50.300 8 207 3.8E-29 T 23-10-2018 TAM4_2114 6c75a1e27374130385a57ef03457d5af 324 SUPERFAMILY SSF47240 19 167 3.67E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_2114 6c75a1e27374130385a57ef03457d5af 324 Pfam PF05763 Protein of unknown function (DUF835) 186 318 8.8E-21 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_2114 6c75a1e27374130385a57ef03457d5af 324 Pfam PF02915 Rubrerythrin 27 161 2.6E-26 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2114 6c75a1e27374130385a57ef03457d5af 324 Gene3D G3DSA:1.20.1260.10 17 165 1.3E-35 T 23-10-2018 IPR012347 Ferritin-like TAM4_1082 1d36fbfad2597b10f1e8802ebcb974c5 246 Pfam PF01061 ABC-2 type transporter 7 207 6.3E-22 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TAM4_1082 1d36fbfad2597b10f1e8802ebcb974c5 246 PIRSF PIRSF006648 2 243 1.5E-18 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TAM4_1089 2b7664fe031d47356aab9a579cf55402 245 PIRSF PIRSF006601 1 245 2.8E-85 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related TAM4_1089 2b7664fe031d47356aab9a579cf55402 245 SUPERFAMILY SSF52402 49 189 2.46E-16 T 23-10-2018 TAM4_1089 2b7664fe031d47356aab9a579cf55402 245 Gene3D G3DSA:3.40.50.620 22 190 8.8E-9 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1172 7da402f8d2f1caca553c4166d9c7fad7 140 Gene3D G3DSA:3.40.50.300 1 135 7.8E-17 T 23-10-2018 TAM4_1172 7da402f8d2f1caca553c4166d9c7fad7 140 SUPERFAMILY SSF52540 2 78 6.2E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 Gene3D G3DSA:1.10.10.10 293 362 6.1E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 SUPERFAMILY SSF46785 291 360 1.63E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 Gene3D G3DSA:1.10.8.60 214 292 1.3E-27 T 23-10-2018 TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 Gene3D G3DSA:3.40.50.300 1 212 1.2E-43 T 23-10-2018 TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 Pfam PF01637 ATPase domain predominantly from Archaea 15 252 2.0E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_946 ad0c936ff5efad619d9d4ffcff87ac5c 374 SUPERFAMILY SSF52540 3 292 1.78E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2325 197276eaa7631be6d80a9483cb855c2f 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 91 3.6E-28 T 23-10-2018 IPR002767 Thiamine-binding protein TAM4_2325 197276eaa7631be6d80a9483cb855c2f 93 Gene3D G3DSA:3.30.70.930 1 93 7.8E-34 T 23-10-2018 IPR029756 MTH1187/YkoF-like TAM4_2325 197276eaa7631be6d80a9483cb855c2f 93 Pfam PF01910 Thiamine-binding protein 4 91 3.7E-31 T 23-10-2018 IPR002767 Thiamine-binding protein TAM4_2325 197276eaa7631be6d80a9483cb855c2f 93 SUPERFAMILY SSF89957 1 92 5.49E-31 T 23-10-2018 IPR029756 MTH1187/YkoF-like TAM4_123 b3badba811d6edee133c8990e4d3f5fe 99 Pfam PF04930 FUN14 family 12 96 4.3E-12 T 23-10-2018 IPR007014 FUN14 TAM4_888 753865a8937886375b5f3034a1e48885 334 SUPERFAMILY SSF56042 166 327 3.29E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_888 753865a8937886375b5f3034a1e48885 334 Gene3D G3DSA:3.30.1330.10 2 165 5.3E-52 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_888 753865a8937886375b5f3034a1e48885 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 324 9.2E-25 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_888 753865a8937886375b5f3034a1e48885 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 4.4E-123 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_888 753865a8937886375b5f3034a1e48885 334 SUPERFAMILY SSF55326 2 165 2.54E-39 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_888 753865a8937886375b5f3034a1e48885 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.503 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_888 753865a8937886375b5f3034a1e48885 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 3.5E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_888 753865a8937886375b5f3034a1e48885 334 Gene3D G3DSA:3.90.650.10 166 332 5.8E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_1913 6b9371a4755327a84051617564700126 259 SUPERFAMILY SSF102522 1 161 4.97E-56 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TAM4_1913 6b9371a4755327a84051617564700126 259 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 251 7.2E-75 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TAM4_1913 6b9371a4755327a84051617564700126 259 Gene3D G3DSA:3.40.50.10790 1 160 3.8E-61 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TAM4_1913 6b9371a4755327a84051617564700126 259 PIRSF PIRSF006779 1 256 1.8E-74 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TAM4_1913 6b9371a4755327a84051617564700126 259 Gene3D G3DSA:2.40.30.90 161 256 3.9E-33 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TAM4_1913 6b9371a4755327a84051617564700126 259 SUPERFAMILY SSF101852 163 254 1.96E-23 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 Pfam PF00005 ABC transporter 17 167 5.2E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 Gene3D G3DSA:3.40.50.300 1 238 8.1E-56 T 23-10-2018 TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 SMART SM00382 26 219 6.2E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 238 7.0E-86 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TAM4_920 e04a9ba55154138e3b1e3be00a1a7617 246 SUPERFAMILY SSF52540 2 225 1.22E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 SMART SM01407 6 66 1.1E-17 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 Gene3D G3DSA:2.20.70.30 10 69 1.0E-21 T 23-10-2018 IPR038187 NAC A/B domain superfamily TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.675 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 Pfam PF01849 NAC domain 6 62 2.3E-11 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 SUPERFAMILY SSF46934 72 111 1.16E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 5.0E-37 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TAM4_2454 2c0f0c299bc8130bdc910b8101b47aeb 112 Gene3D G3DSA:1.10.8.10 70 109 1.6E-20 T 23-10-2018 TAM4_1645 1fa1dda677f6e1d82ce99bf742a12540 293 Gene3D G3DSA:3.30.930.10 8 255 3.9E-32 T 23-10-2018 TAM4_1645 1fa1dda677f6e1d82ce99bf742a12540 293 Pfam PF13393 Histidyl-tRNA synthetase 190 255 2.8E-11 T 23-10-2018 TAM4_1645 1fa1dda677f6e1d82ce99bf742a12540 293 Pfam PF13393 Histidyl-tRNA synthetase 7 179 2.3E-14 T 23-10-2018 TAM4_1645 1fa1dda677f6e1d82ce99bf742a12540 293 SUPERFAMILY SSF55681 10 253 2.62E-33 T 23-10-2018 TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 Pfam PF01545 Cation efflux family 12 201 4.1E-51 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 Gene3D G3DSA:3.30.70.1350 202 280 1.3E-7 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 SUPERFAMILY SSF160240 205 278 4.45E-14 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 Gene3D G3DSA:1.20.1510.10 7 201 1.4E-50 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 278 1.5E-10 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 SUPERFAMILY SSF161111 6 202 9.94E-59 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TAM4_1355 6044ff8529ea2ea1386ff11ff7ca1603 293 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 280 1.2E-91 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 Gene3D G3DSA:3.20.20.70 151 450 2.4E-55 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 Pfam PF04055 Radical SAM superfamily 155 311 7.4E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 405 491 1.1E-13 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 Pfam PF13186 Iron-sulfur cluster-binding domain 405 465 4.9E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 SMART SM00729 150 350 2.9E-21 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 SUPERFAMILY SSF102114 149 472 1.44E-75 T 23-10-2018 TAM4_459 813c1e85822a6abb8b7eee68b50dfc8e 554 Pfam PF13353 4Fe-4S single cluster domain 152 265 1.1E-10 T 23-10-2018 TAM4_1451 ff1c7085cc543bc742313b486095dde0 380 Gene3D G3DSA:1.20.1530.20 2 379 8.7E-94 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_1451 ff1c7085cc543bc742313b486095dde0 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 2.4E-63 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 SMART SM00490 259 341 2.4E-24 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 SUPERFAMILY SSF52540 28 350 1.86E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 SMART SM00487 12 210 3.5E-35 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 Gene3D G3DSA:3.40.50.300 213 370 1.7E-30 T 23-10-2018 TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 Pfam PF08494 DEAD/H associated 583 750 5.0E-19 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 Gene3D G3DSA:3.40.50.300 3 202 7.7E-46 T 23-10-2018 TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 Pfam PF00271 Helicase conserved C-terminal domain 237 336 3.1E-19 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_1813 42c63e09fcd90675ff6062362c7c9779 926 Pfam PF00270 DEAD/DEAH box helicase 18 182 7.3E-28 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_44 e5daebec91f3b4334d651bc6b1d4503a 229 SUPERFAMILY SSF53335 9 168 5.27E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_44 e5daebec91f3b4334d651bc6b1d4503a 229 Pfam PF13649 Methyltransferase domain 42 137 3.0E-27 T 23-10-2018 TAM4_44 e5daebec91f3b4334d651bc6b1d4503a 229 Gene3D G3DSA:3.40.50.150 1 228 6.4E-70 T 23-10-2018 TAM4_1183 aa3160b3d138d8e7249f26380d00c4f2 83 SUPERFAMILY SSF158436 3 83 5.23E-30 T 23-10-2018 TAM4_1183 aa3160b3d138d8e7249f26380d00c4f2 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 2.0E-39 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TAM4_1183 aa3160b3d138d8e7249f26380d00c4f2 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 2.4E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TAM4_1183 aa3160b3d138d8e7249f26380d00c4f2 83 Hamap MF_00342 UPF0147 protein . 1 83 29.722 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TAM4_1183 aa3160b3d138d8e7249f26380d00c4f2 83 Gene3D G3DSA:1.20.1440.50 1 83 3.0E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily TAM4_22 51dcbffc52e4ce2c1305536ec1cd7598 121 Gene3D G3DSA:3.100.10.10 6 121 2.3E-41 T 23-10-2018 TAM4_22 51dcbffc52e4ce2c1305536ec1cd7598 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_22 51dcbffc52e4ce2c1305536ec1cd7598 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 1.9E-16 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TAM4_22 51dcbffc52e4ce2c1305536ec1cd7598 121 SUPERFAMILY SSF52080 6 120 2.09E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TAM4_22 51dcbffc52e4ce2c1305536ec1cd7598 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 31.038 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 Gene3D G3DSA:3.90.920.10 9 326 6.2E-120 T 23-10-2018 TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 Gene3D G3DSA:1.10.8.160 176 277 6.2E-120 T 23-10-2018 TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 Pfam PF01896 DNA primase small subunit 96 306 4.4E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 SUPERFAMILY SSF56747 4 339 3.27E-91 T 23-10-2018 TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 340 22.539 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 TAM4_2455 84aba4446d341b2877f3857f66b97d9d 342 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 329 4.3E-57 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Gene3D G3DSA:3.10.580.10 130 274 6.5E-37 T 23-10-2018 TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 PIRSF PIRSF036983 2 390 1.2E-142 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 SUPERFAMILY SSF54631 4 122 1.39E-17 T 23-10-2018 TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 SMART SM00116 75 123 1.3 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 SMART SM00116 217 265 1.9E-9 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 SMART SM00116 139 187 1.5E-9 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Pfam PF00571 CBS domain 6 54 0.0068 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Pfam PF00571 CBS domain 132 183 1.6E-16 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Pfam PF00571 CBS domain 69 122 1.3E-4 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Pfam PF00571 CBS domain 211 261 1.1E-12 T 23-10-2018 IPR000644 CBS domain TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 Gene3D G3DSA:3.10.580.10 1 129 2.2E-16 T 23-10-2018 TAM4_878 7146df96f4e37fcb4f50008512ea2ea1 390 SUPERFAMILY SSF54631 127 261 1.22E-35 T 23-10-2018 TAM4_1818 29b29d1030311b14e459c72a95dc25ba 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 5 409 7.9E-114 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TAM4_1818 29b29d1030311b14e459c72a95dc25ba 421 SUPERFAMILY SSF143968 283 419 1.44E-41 T 23-10-2018 TAM4_1818 29b29d1030311b14e459c72a95dc25ba 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 6 385 1.4E-101 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TAM4_1818 29b29d1030311b14e459c72a95dc25ba 421 SUPERFAMILY SSF50475 5 279 3.61E-66 T 23-10-2018 TAM4_1818 29b29d1030311b14e459c72a95dc25ba 421 Gene3D G3DSA:3.40.1670.10 296 408 3.2E-38 T 23-10-2018 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 SMART SM01118 1 166 3.2E-10 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 Pfam PF01928 CYTH domain 2 160 2.8E-24 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 SUPERFAMILY SSF55154 1 164 6.38E-39 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 165 7.4E-28 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 Gene3D G3DSA:2.40.320.10 1 168 1.4E-48 T 23-10-2018 TAM4_1962 aeb0c77292ce19321a348056fed9460c 169 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 5.0E-38 T 23-10-2018 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 6.3E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 Gene3D G3DSA:3.40.50.300 3 334 5.3E-96 T 23-10-2018 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 Pfam PF00005 ABC transporter 37 191 3.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 SUPERFAMILY SSF52540 5 263 1.27E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 1.8E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_1452 52fd3ad95db419d5ce9769dfc5a120ac 335 SMART SM00382 45 249 2.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 17 109 1.5E-18 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 SMART SM01400 2 110 9.4E-30 T 23-10-2018 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 277 3.7E-86 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 Pfam PF00156 Phosphoribosyl transferase domain 142 242 1.0E-18 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 35.5 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 Gene3D G3DSA:3.40.50.2020 139 263 6.7E-77 T 23-10-2018 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 Gene3D G3DSA:3.40.50.2020 17 138 6.7E-77 T 23-10-2018 TAM4_93 595add27e3a48320a1cc3dfb19249d0d 279 SUPERFAMILY SSF53271 62 270 1.55E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_1109 d0a3e234b8185b3182c0df77c183d031 235 Pfam PF06745 KaiC 7 228 8.3E-45 T 23-10-2018 IPR014774 KaiC-like domain TAM4_1109 d0a3e234b8185b3182c0df77c183d031 235 Gene3D G3DSA:3.40.50.300 4 230 1.4E-53 T 23-10-2018 TAM4_1109 d0a3e234b8185b3182c0df77c183d031 235 SUPERFAMILY SSF52540 5 226 2.46E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_549 ffb7610e5744e4cb5095a20f152a0b2a 93 PIRSF PIRSF029904 1 92 3.0E-27 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TAM4_549 ffb7610e5744e4cb5095a20f152a0b2a 93 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 22 89 2.8E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TAM4_549 ffb7610e5744e4cb5095a20f152a0b2a 93 SUPERFAMILY SSF101386 3 91 4.09E-21 T 23-10-2018 TAM4_549 ffb7610e5744e4cb5095a20f152a0b2a 93 Gene3D G3DSA:1.10.287.1080 1 93 5.6E-24 T 23-10-2018 TAM4_2194 79c00936033ddbc904317473e9577770 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 1.2E-26 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TAM4_2194 79c00936033ddbc904317473e9577770 115 SUPERFAMILY SSF55620 1 113 1.61E-31 T 23-10-2018 TAM4_2194 79c00936033ddbc904317473e9577770 115 Gene3D G3DSA:3.30.479.10 1 115 9.4E-39 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TAM4_2194 79c00936033ddbc904317473e9577770 115 PIRSF PIRSF006113 1 115 7.6E-34 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TAM4_199 91d51dc785bc313759a6c977140ba97e 429 Gene3D G3DSA:3.40.50.300 237 396 1.2E-13 T 23-10-2018 TAM4_199 91d51dc785bc313759a6c977140ba97e 429 SUPERFAMILY SSF52540 2 398 1.21E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_199 91d51dc785bc313759a6c977140ba97e 429 Pfam PF13175 AAA ATPase domain 3 47 1.0E-13 T 23-10-2018 TAM4_199 91d51dc785bc313759a6c977140ba97e 429 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 252 375 1.1E-21 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_199 91d51dc785bc313759a6c977140ba97e 429 PIRSF PIRSF029347 1 95 4.5E-12 T 23-10-2018 IPR014555 RecF-like TAM4_199 91d51dc785bc313759a6c977140ba97e 429 PIRSF PIRSF029347 232 409 4.5E-16 T 23-10-2018 IPR014555 RecF-like TAM4_199 91d51dc785bc313759a6c977140ba97e 429 Gene3D G3DSA:3.40.50.300 1 126 1.3E-12 T 23-10-2018 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 SUPERFAMILY SSF52374 3 366 3.44E-92 T 23-10-2018 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 80 89 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 378 5.7E-106 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 Gene3D G3DSA:1.10.240.10 254 382 1.3E-44 T 23-10-2018 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 4 364 45.872 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 Gene3D G3DSA:3.40.50.620 1 253 6.7E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 206 227 2.6E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 250 260 2.6E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 84 100 2.6E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 136 155 2.6E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TAM4_1178 d9bd5176fe25905edd9720e5b888cbbb 382 Pfam PF00579 tRNA synthetases class I (W and Y) 72 345 2.8E-26 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Gene3D G3DSA:2.60.40.10 762 857 3.5E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2932 2953 7900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2319 2339 9600.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2224 2244 2800.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2957 2978 6400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 484 507 990.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 508 535 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2364 2386 380.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2903 2924 83.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 536 558 1100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2340 2361 13.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2861 2881 1300.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2882 2901 1200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00710 2817 2848 2900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Gene3D G3DSA:2.160.20.10 394 682 2.2E-16 T 23-10-2018 IPR012334 Pectin lyase fold TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Gene3D G3DSA:2.60.120.260 2647 2792 1.2E-9 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00060 315 386 19.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00060 1237 1305 46.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00060 1785 1969 1.1 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SMART SM00060 1023 1118 65.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SUPERFAMILY SSF51126 396 650 3.97E-22 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SUPERFAMILY SSF51126 2218 2412 1.54E-9 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 SUPERFAMILY SSF51126 2808 2988 9.76E-14 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Pfam PF13229 Right handed beta helix region 483 629 4.9E-9 T 23-10-2018 IPR039448 Right handed beta helix domain TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Pfam PF13229 Right handed beta helix region 2804 2934 3.2E-8 T 23-10-2018 IPR039448 Right handed beta helix domain TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 Gene3D G3DSA:2.60.40.10 1503 1590 2.8E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1797 200e5268b33690282284f7176fb9e00f 4292 TIGRFAM TIGR04213 PGF_pre_PGF: PGF-pre-PGF domain 4144 4234 2.1E-8 T 23-10-2018 IPR026453 PGF-pre-PGF domain TAM4_152 f1e93d67290bc30c7b1ea0040f4d85fb 448 SUPERFAMILY SSF52540 125 299 1.76E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_152 f1e93d67290bc30c7b1ea0040f4d85fb 448 Gene3D G3DSA:3.40.50.720 3 132 2.4E-8 T 23-10-2018 TAM4_152 f1e93d67290bc30c7b1ea0040f4d85fb 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 1.4E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TAM4_152 f1e93d67290bc30c7b1ea0040f4d85fb 448 Gene3D G3DSA:3.40.50.300 212 306 1.1E-8 T 23-10-2018 TAM4_126 2603a4e65da495dfc34b003bce3914b2 193 Gene3D G3DSA:3.40.50.300 5 112 1.0E-11 T 23-10-2018 TAM4_126 2603a4e65da495dfc34b003bce3914b2 193 SUPERFAMILY SSF52540 8 118 1.98E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_572 34f92aa727ba0dee549234119343586a 326 SUPERFAMILY SSF52540 34 323 6.74E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_572 34f92aa727ba0dee549234119343586a 326 Pfam PF00005 ABC transporter 26 189 2.1E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_572 34f92aa727ba0dee549234119343586a 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 1.2E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_572 34f92aa727ba0dee549234119343586a 326 Gene3D G3DSA:3.40.50.300 3 326 3.0E-100 T 23-10-2018 TAM4_572 34f92aa727ba0dee549234119343586a 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_572 34f92aa727ba0dee549234119343586a 326 SMART SM00382 34 247 1.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_572 34f92aa727ba0dee549234119343586a 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 7.5E-22 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TAM4_1149 fdefe144b73c98ef9140414dda7d2fa3 311 SUPERFAMILY SSF82866 127 295 3.01E-23 T 23-10-2018 TAM4_1149 fdefe144b73c98ef9140414dda7d2fa3 311 Pfam PF02355 Protein export membrane protein 131 297 2.2E-29 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TAM4_1149 fdefe144b73c98ef9140414dda7d2fa3 311 Gene3D G3DSA:1.20.1640.10 123 300 1.8E-10 T 23-10-2018 TAM4_1149 fdefe144b73c98ef9140414dda7d2fa3 311 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 302 25.815 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 TAM4_164 8274ddaca87c58a713bb0b764d6a3814 73 SUPERFAMILY SSF143100 6 57 9.55E-12 T 23-10-2018 IPR035069 TTHA1013/TTHA0281-like TAM4_164 8274ddaca87c58a713bb0b764d6a3814 73 Gene3D G3DSA:3.30.160.250 3 69 1.5E-10 T 23-10-2018 TAM4_1697 1e3dccded1f96e93c6f5846363ce1528 196 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 61 193 6.7E-43 T 23-10-2018 IPR005247 YbhB/YbcL TAM4_1697 1e3dccded1f96e93c6f5846363ce1528 196 SUPERFAMILY SSF49777 49 195 7.85E-44 T 23-10-2018 IPR036610 PEBP-like superfamily TAM4_1697 1e3dccded1f96e93c6f5846363ce1528 196 Gene3D G3DSA:3.90.280.10 45 196 2.3E-50 T 23-10-2018 IPR036610 PEBP-like superfamily TAM4_1697 1e3dccded1f96e93c6f5846363ce1528 196 Pfam PF01161 Phosphatidylethanolamine-binding protein 57 193 1.5E-34 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 197 229 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 197 218 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 139 165 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 78 105 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 7 31 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 268 293 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 168 193 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 309 327 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 105 131 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 PRINTS PR00083 Histidinol dehydrogenase signature 219 238 8.4E-96 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 Gene3D G3DSA:3.40.50.1980 4 200 8.2E-95 T 23-10-2018 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 375 36.206 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 Pfam PF00815 Histidinol dehydrogenase 3 246 6.2E-91 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 Pfam PF00815 Histidinol dehydrogenase 254 374 1.0E-38 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 SUPERFAMILY SSF53720 5 374 6.67E-58 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 Gene3D G3DSA:3.40.50.1980 201 297 8.2E-95 T 23-10-2018 TAM4_1682 ea89262f40228c54dd05e28191bcde1b 375 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 7 246 4.9E-91 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TAM4_109 10b491b8095f6a3e92d2998a12727508 370 Gene3D G3DSA:3.40.50.2000 197 360 1.3E-41 T 23-10-2018 TAM4_109 10b491b8095f6a3e92d2998a12727508 370 Pfam PF13439 Glycosyltransferase Family 4 19 185 5.2E-24 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TAM4_109 10b491b8095f6a3e92d2998a12727508 370 Gene3D G3DSA:3.40.50.2000 2 196 3.7E-25 T 23-10-2018 TAM4_109 10b491b8095f6a3e92d2998a12727508 370 SUPERFAMILY SSF53756 5 365 6.81E-73 T 23-10-2018 TAM4_109 10b491b8095f6a3e92d2998a12727508 370 Pfam PF00534 Glycosyl transferases group 1 193 348 5.5E-40 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TAM4_1678 71f4bdd02f20b66a38824e30519f3996 178 SMART SM00382 1 157 4.0E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1678 71f4bdd02f20b66a38824e30519f3996 178 Hamap MF_00796 Nucleoside-triphosphatase . 2 174 29.425 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TAM4_1678 71f4bdd02f20b66a38824e30519f3996 178 SUPERFAMILY SSF52540 4 154 7.97E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1678 71f4bdd02f20b66a38824e30519f3996 178 Gene3D G3DSA:3.40.50.300 2 177 1.3E-41 T 23-10-2018 TAM4_1678 71f4bdd02f20b66a38824e30519f3996 178 Pfam PF03266 NTPase 3 166 4.9E-54 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TAM4_169 902ec77440107c0db4016b04f3f840da 454 Pfam PF01957 NfeD-like C-terminal, partner-binding 300 444 4.4E-34 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TAM4_169 902ec77440107c0db4016b04f3f840da 454 Pfam PF00574 Clp protease 58 194 4.2E-5 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TAM4_169 902ec77440107c0db4016b04f3f840da 454 SUPERFAMILY SSF52096 21 196 1.04E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TAM4_169 902ec77440107c0db4016b04f3f840da 454 Gene3D G3DSA:3.90.226.10 26 249 8.4E-66 T 23-10-2018 TAM4_169 902ec77440107c0db4016b04f3f840da 454 Gene3D G3DSA:2.40.50.140 380 453 2.1E-24 T 23-10-2018 TAM4_169 902ec77440107c0db4016b04f3f840da 454 SUPERFAMILY SSF141322 377 443 2.88E-14 T 23-10-2018 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 3.0E-24 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 17 334 9.1E-138 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.761 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 SUPERFAMILY SSF88697 249 332 7.18E-23 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Gene3D G3DSA:2.30.130.70 23 332 4.9E-149 T 23-10-2018 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Pfam PF01472 PUA domain 251 323 4.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 SMART SM00359 251 325 1.1E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 SUPERFAMILY SSF55120 21 247 1.9E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 2.9E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 241 320 2.2E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Gene3D G3DSA:3.30.2350.10 40 243 4.9E-149 T 23-10-2018 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 180 1.1E-21 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TAM4_206 46eb4e69cb9b98856c79edcfdf26fbbf 334 SMART SM01136 4 63 3.5E-26 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TAM4_2187 3678481c953b85d3ee8f5bec52150188 213 Gene3D G3DSA:3.40.50.11570 5 213 4.7E-53 T 23-10-2018 TAM4_2187 3678481c953b85d3ee8f5bec52150188 213 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 211 6.3E-45 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 Pfam PF00107 Zinc-binding dehydrogenase 178 306 1.3E-28 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 Gene3D G3DSA:3.90.180.10 21 338 2.9E-132 T 23-10-2018 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 1.5E-35 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 Gene3D G3DSA:3.40.50.720 157 291 2.9E-132 T 23-10-2018 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 SMART SM00829 16 345 1.3E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 1.1E-176 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 SUPERFAMILY SSF51735 146 310 1.29E-33 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 SUPERFAMILY SSF50129 3 177 3.65E-53 T 23-10-2018 IPR011032 GroES-like superfamily TAM4_1945 fb4416a34a13a5971c87049b52cfb98e 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TAM4_1993 2333548cc955585c941dbb88e61eddbb 485 SUPERFAMILY SSF50475 2 316 2.79E-83 T 23-10-2018 TAM4_1993 2333548cc955585c941dbb88e61eddbb 485 SUPERFAMILY SSF143968 317 478 2.22E-53 T 23-10-2018 TAM4_1993 2333548cc955585c941dbb88e61eddbb 485 Gene3D G3DSA:3.40.1670.10 331 447 2.9E-41 T 23-10-2018 TAM4_1993 2333548cc955585c941dbb88e61eddbb 485 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 8 423 1.6E-127 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TAM4_1993 2333548cc955585c941dbb88e61eddbb 485 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 4 448 1.4E-120 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TAM4_1050 67e759ea1d375e2e113795e34108d4ab 316 SUPERFAMILY SSF101960 65 316 7.98E-47 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TAM4_1050 67e759ea1d375e2e113795e34108d4ab 316 Pfam PF01458 Uncharacterized protein family (UPF0051) 95 312 1.4E-33 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 Gene3D G3DSA:3.40.50.300 1 243 7.0E-78 T 23-10-2018 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 SUPERFAMILY SSF50331 242 370 1.09E-24 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 SMART SM00382 28 217 1.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 Gene3D G3DSA:2.40.50.140 310 354 2.1E-24 T 23-10-2018 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 Pfam PF08402 TOBE domain 288 363 1.4E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 Gene3D G3DSA:2.40.50.100 245 304 9.4E-26 T 23-10-2018 TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 SUPERFAMILY SSF52540 4 249 9.38E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_696 93b4f51b9bbe9027ce14ba1dbef2b3b7 371 Pfam PF00005 ABC transporter 20 167 2.7E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 SMART SM00729 78 373 3.9E-49 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 Pfam PF00583 Acetyltransferase (GNAT) family 455 560 2.0E-8 T 23-10-2018 IPR000182 GNAT domain TAM4_1122 36084948d2e39ca29e49261fa737da51 590 Gene3D G3DSA:3.80.30.20 231 381 6.7E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TAM4_1122 36084948d2e39ca29e49261fa737da51 590 SUPERFAMILY SSF55729 440 570 4.29E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1122 36084948d2e39ca29e49261fa737da51 590 SUPERFAMILY SSF102114 83 380 3.79E-35 T 23-10-2018 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 Gene3D G3DSA:3.40.630.30 421 571 6.4E-9 T 23-10-2018 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 Pfam PF16199 Radical_SAM C-terminal domain 334 413 3.1E-26 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 Pfam PF04055 Radical SAM superfamily 85 318 7.4E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 PIRSF PIRSF005669 1 572 3.4E-250 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TAM4_1122 36084948d2e39ca29e49261fa737da51 590 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 15 571 7.3E-265 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 617 640 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 Pfam PF00069 Protein kinase domain 611 815 2.5E-39 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 Pfam PF00069 Protein kinase domain 80 318 1.9E-44 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 SMART SM00220 611 871 3.9E-40 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 SMART SM00220 80 324 1.1E-55 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 Gene3D G3DSA:1.10.510.10 604 932 2.9E-57 T 23-10-2018 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 Gene3D G3DSA:1.10.510.10 60 339 7.9E-63 T 23-10-2018 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 SUPERFAMILY SSF56112 605 871 1.89E-59 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 86 108 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 SUPERFAMILY SSF56112 79 321 2.02E-64 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_2334 a7714aa5330d90671d4c8bbfd0dea60a 980 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 730 742 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_577 07ba664ef49ea9d7c80961dd2fa74609 206 Gene3D G3DSA:2.40.50.140 23 92 1.3E-22 T 23-10-2018 TAM4_577 07ba664ef49ea9d7c80961dd2fa74609 206 Gene3D G3DSA:1.10.150.280 93 190 2.9E-41 T 23-10-2018 TAM4_577 07ba664ef49ea9d7c80961dd2fa74609 206 SUPERFAMILY SSF160975 23 199 3.01E-93 T 23-10-2018 TAM4_577 07ba664ef49ea9d7c80961dd2fa74609 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 5.6E-70 T 23-10-2018 IPR007003 Protein of unknown function DUF655 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.652 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 2.6E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 SMART SM01403 5 99 7.5E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.2E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 SUPERFAMILY SSF54999 3 100 4.05E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 Gene3D G3DSA:3.30.70.600 1 101 5.7E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TAM4_862 4864fb8cf36af2a068e2959122c83e0b 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_657 dcb29b576fcb392a10d2064076e8f5f6 157 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 9 156 9.792 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_657 dcb29b576fcb392a10d2064076e8f5f6 157 SMART SM00670 7 150 6.9E-9 T 23-10-2018 IPR002716 PIN domain TAM4_657 dcb29b576fcb392a10d2064076e8f5f6 157 Gene3D G3DSA:3.40.50.1010 8 156 1.3E-11 T 23-10-2018 TAM4_657 dcb29b576fcb392a10d2064076e8f5f6 157 Pfam PF01850 PIN domain 9 151 1.9E-19 T 23-10-2018 IPR002716 PIN domain TAM4_657 dcb29b576fcb392a10d2064076e8f5f6 157 SUPERFAMILY SSF88723 9 156 4.21E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 217 619 1.1E-127 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 Gene3D G3DSA:1.10.569.10 238 441 4.6E-133 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 3.0E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 SMART SM00790 4 204 1.3E-107 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 SUPERFAMILY SSF56228 1 206 3.92E-66 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 Gene3D G3DSA:1.10.599.10 236 619 4.6E-133 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 Gene3D G3DSA:3.60.9.10 1 208 1.2E-75 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_1594 042081eb22bf0d5ad60c6e4699df5ecd 630 SUPERFAMILY SSF48310 211 626 7.06E-119 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 Gene3D G3DSA:2.30.40.10 4 415 3.4E-156 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 SUPERFAMILY SSF51556 54 347 1.99E-104 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 Pfam PF01979 Amidohydrolase family 51 397 9.5E-79 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 SUPERFAMILY SSF51338 1 423 1.3E-37 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 47.908 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 TAM4_1160 9752d34c49ec4ff42da6d6dcfb6832bd 424 Gene3D G3DSA:3.20.20.140 55 344 3.4E-156 T 23-10-2018 TAM4_955 02b0438522ba273608d2238366f97322 62 Pfam PF01954 Protein of unknown function DUF104 1 59 5.0E-11 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_955 02b0438522ba273608d2238366f97322 62 SUPERFAMILY SSF141694 1 55 1.33E-11 T 23-10-2018 TAM4_955 02b0438522ba273608d2238366f97322 62 Gene3D G3DSA:4.10.1150.10 1 61 1.0E-7 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_1099 a59b9ae53b70671cda41602a25d2f9ba 119 Pfam PF02830 V4R domain 60 117 3.0E-10 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR TAM4_1099 a59b9ae53b70671cda41602a25d2f9ba 119 SMART SM00989 57 118 6.1E-10 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR TAM4_1099 a59b9ae53b70671cda41602a25d2f9ba 119 Gene3D G3DSA:3.30.1380.20 4 119 1.0E-25 T 23-10-2018 TAM4_1099 a59b9ae53b70671cda41602a25d2f9ba 119 SUPERFAMILY SSF111126 12 116 1.67E-24 T 23-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily TAM4_672 18fd2ae0f950078b8838c75d4a244d28 985 Gene3D G3DSA:2.60.40.3030 845 975 8.7E-111 T 23-10-2018 TAM4_672 18fd2ae0f950078b8838c75d4a244d28 985 Gene3D G3DSA:2.40.128.390 624 698 1.3E-95 T 23-10-2018 TAM4_672 18fd2ae0f950078b8838c75d4a244d28 985 Gene3D G3DSA:3.40.50.12610 517 739 1.3E-95 T 23-10-2018 TAM4_672 18fd2ae0f950078b8838c75d4a244d28 985 Gene3D G3DSA:2.60.40.3020 740 983 8.7E-111 T 23-10-2018 TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 1.8E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 SUPERFAMILY SSF50193 16 141 4.06E-44 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 Gene3D G3DSA:2.40.150.20 1 140 3.9E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.561 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 Pfam PF00238 Ribosomal protein L14p/L23e 23 140 1.1E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TAM4_79 a75b75f0ea9c88823ccfa9762787e9da 141 SMART SM01374 20 141 6.9E-57 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 SUPERFAMILY SSF54814 88 141 4.12E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 1.4E-60 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 Gene3D G3DSA:3.30.300.20 2 73 2.3E-28 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 SUPERFAMILY SSF54814 12 74 9.81E-12 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 Pfam PF07650 KH domain 12 94 2.1E-17 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 SMART SM00322 32 115 0.0031 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.297 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TAM4_1521 68babe395cb7bef6a8fb1beb9613b128 145 Gene3D G3DSA:3.30.300.20 74 144 3.8E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 ProSitePatterns PS00534 Ferrochelatase signature. 167 185 - T 23-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 Gene3D G3DSA:3.40.50.1400 2 285 1.5E-56 T 23-10-2018 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 Pfam PF00762 Ferrochelatase 3 288 1.7E-59 T 23-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 Gene3D G3DSA:3.40.50.1400 140 275 1.5E-56 T 23-10-2018 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 SUPERFAMILY SSF53800 3 295 7.52E-61 T 23-10-2018 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 Hamap MF_00323 Ferrochelatase [hemH]. 1 294 22.192 T 23-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TAM4_2206 93b9401acf58933662ffae6c5baafc37 298 TIGRFAM TIGR00109 hemH: ferrochelatase 3 281 6.8E-49 T 23-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 SMART SM00089 1171 1252 1.7E-11 T 23-10-2018 IPR022409 PKD/Chitinase domain TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 SMART SM00089 1274 1338 15.0 T 23-10-2018 IPR022409 PKD/Chitinase domain TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 SMART SM00327 48 232 5.4E-14 T 23-10-2018 IPR002035 von Willebrand factor, type A TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 Gene3D G3DSA:2.60.40.10 1169 1249 9.3E-16 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 Gene3D G3DSA:2.60.40.10 1253 1342 8.1E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 Pfam PF00092 von Willebrand factor type A domain 50 205 1.0E-12 T 23-10-2018 IPR002035 von Willebrand factor, type A TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 Pfam PF00801 PKD domain 1177 1236 3.7E-10 T 23-10-2018 IPR000601 PKD domain TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 Gene3D G3DSA:3.40.50.410 47 231 4.8E-19 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 SUPERFAMILY SSF53300 48 233 1.47E-29 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TAM4_1617 6eccad8ab750d607532d594a2eb42c2f 1384 SUPERFAMILY SSF49299 1162 1252 4.05E-16 T 23-10-2018 IPR035986 PKD domain superfamily TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 Pfam PF01769 Divalent cation transporter 259 384 4.4E-15 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 Pfam PF01769 Divalent cation transporter 56 179 5.2E-22 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 SUPERFAMILY SSF161093 12 185 4.84E-31 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 Gene3D G3DSA:1.10.357.20 7 185 8.7E-10 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 Gene3D G3DSA:1.10.357.20 212 391 6.3E-11 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TAM4_604 7ced7ea909e0847c8c3d17929dfb9e4d 393 SUPERFAMILY SSF161093 219 391 1.83E-24 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 50.043 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 Pfam PF08608 Wyosine base formation 255 315 1.5E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 SUPERFAMILY SSF102114 71 278 6.87E-18 T 23-10-2018 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 Gene3D G3DSA:3.20.20.70 2 333 2.5E-134 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 18 314 8.7E-132 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TAM4_564 c05abab769a932392acaf5e7e7755c5c 333 Pfam PF04055 Radical SAM superfamily 67 252 3.0E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_429 6ca2192f8c62fc0449a2e2dc46afade4 191 Pfam PF04493 Endonuclease V 15 137 8.7E-33 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TAM4_429 6ca2192f8c62fc0449a2e2dc46afade4 191 Pfam PF04493 Endonuclease V 143 179 1.1E-4 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TAM4_429 6ca2192f8c62fc0449a2e2dc46afade4 191 Hamap MF_00801 Endonuclease V [nfi]. 4 189 26.729 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TAM4_429 6ca2192f8c62fc0449a2e2dc46afade4 191 Gene3D G3DSA:3.30.2170.10 1 141 5.8E-37 T 23-10-2018 TAM4_429 6ca2192f8c62fc0449a2e2dc46afade4 191 Gene3D G3DSA:3.30.2170.10 142 190 7.0E-7 T 23-10-2018 TAM4_1528 878ff57792aaa27d3e284583b19cac2f 111 SUPERFAMILY SSF46785 20 110 1.3E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1528 878ff57792aaa27d3e284583b19cac2f 111 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 12 100 2.4E-34 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 TAM4_1528 878ff57792aaa27d3e284583b19cac2f 111 Gene3D G3DSA:1.10.10.10 12 108 2.1E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 Gene3D G3DSA:3.30.160.750 66 129 1.4E-24 T 23-10-2018 TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 Gene3D G3DSA:3.30.360.110 4 65 4.8E-19 T 23-10-2018 TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.623 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 1.2E-44 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 3.0E-38 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TAM4_1241 712508ca1da4d1b9824eced39a5b763d 142 SUPERFAMILY SSF56276 6 120 2.16E-42 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 Pfam PF13424 Tetratricopeptide repeat 470 533 1.5E-7 T 23-10-2018 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 Gene3D G3DSA:3.40.50.300 101 167 7.1E-7 T 23-10-2018 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SUPERFAMILY SSF52540 94 303 1.34E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SUPERFAMILY SSF46785 1 74 4.4E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_213 840054660730747b06ff3ddc9a93a26b 757 Gene3D G3DSA:1.25.40.10 550 747 1.1E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 PRINTS PR00364 Disease resistance protein signature 291 305 1.4E-6 T 23-10-2018 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 PRINTS PR00364 Disease resistance protein signature 202 216 1.4E-6 T 23-10-2018 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 PRINTS PR00364 Disease resistance protein signature 129 144 1.4E-6 T 23-10-2018 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SMART SM00418 5 84 2.6E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 Gene3D G3DSA:1.25.40.10 453 549 9.1E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 Gene3D G3DSA:1.10.10.10 2 91 1.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SUPERFAMILY SSF48452 465 610 5.88E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SUPERFAMILY SSF48452 572 707 5.31E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SMART SM00028 663 696 260.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SMART SM00028 583 616 26.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SMART SM00028 502 535 37.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_213 840054660730747b06ff3ddc9a93a26b 757 SMART SM00028 623 656 230.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_553 1e920ceda51a886543e52b18787d0476 430 SUPERFAMILY SSF56059 118 324 3.36E-51 T 23-10-2018 TAM4_553 1e920ceda51a886543e52b18787d0476 430 SUPERFAMILY SSF52440 8 115 1.87E-33 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TAM4_553 1e920ceda51a886543e52b18787d0476 430 SUPERFAMILY SSF51246 339 410 1.07E-17 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TAM4_553 1e920ceda51a886543e52b18787d0476 430 Gene3D G3DSA:3.30.1490.20 129 200 4.3E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_553 1e920ceda51a886543e52b18787d0476 430 Gene3D G3DSA:3.30.470.20 201 430 1.3E-78 T 23-10-2018 TAM4_553 1e920ceda51a886543e52b18787d0476 430 Pfam PF02222 ATP-grasp domain 127 303 6.3E-55 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TAM4_553 1e920ceda51a886543e52b18787d0476 430 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 49.059 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TAM4_553 1e920ceda51a886543e52b18787d0476 430 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 7.8E-187 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TAM4_553 1e920ceda51a886543e52b18787d0476 430 Gene3D G3DSA:3.40.50.20 1 128 2.8E-55 T 23-10-2018 TAM4_551 6f75d7b2dfd4b3ba05d5e4ef1546e41d 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 1.4E-10 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_551 6f75d7b2dfd4b3ba05d5e4ef1546e41d 49 SMART SM00659 4 49 1.0E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_551 6f75d7b2dfd4b3ba05d5e4ef1546e41d 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.941 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_551 6f75d7b2dfd4b3ba05d5e4ef1546e41d 49 SUPERFAMILY SSF63393 4 48 9.15E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TAM4_551 6f75d7b2dfd4b3ba05d5e4ef1546e41d 49 Gene3D G3DSA:2.20.28.30 1 49 2.0E-23 T 23-10-2018 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 PIRSF PIRSF008955 12 263 1.7E-102 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 Pfam PF09171 N-glycosylase/DNA lyase 23 240 1.5E-85 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 Gene3D G3DSA:1.10.1670.10 21 260 1.4E-84 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 Gene3D G3DSA:1.10.340.30 41 187 1.4E-84 T 23-10-2018 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 260 39.754 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TAM4_1523 dc368159efad44aa8d26b4051af5c73c 263 SUPERFAMILY SSF48150 16 243 7.85E-82 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 5.2E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 5.2E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 Pfam PF00717 Peptidase S24-like 36 91 1.0E-9 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 Gene3D G3DSA:2.10.109.10 36 108 1.9E-6 T 23-10-2018 TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 116 7.4E-17 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TAM4_887 5d1ecdc2b9ddcd85d52c7763c828279b 352 SUPERFAMILY SSF51306 34 99 2.22E-9 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Gene3D G3DSA:2.40.50.140 632 738 3.8E-45 T 23-10-2018 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 SUPERFAMILY SSF50249 637 737 2.94E-38 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 SUPERFAMILY SSF57770 138 172 1.03E-10 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Pfam PF01588 Putative tRNA binding domain 644 735 4.5E-33 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 547 9.0E-178 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Gene3D G3DSA:1.10.730.10 396 546 1.3E-107 T 23-10-2018 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 394 405 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 PRINTS PR01041 Methionyl-tRNA synthetase signature 292 307 7.0E-33 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Pfam PF08264 Anticodon-binding domain of tRNA 428 521 3.8E-12 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 558 43.075 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 SUPERFAMILY SSF52374 2 392 1.77E-105 T 23-10-2018 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 605 738 4.9E-40 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Gene3D G3DSA:2.170.220.10 97 250 4.4E-144 T 23-10-2018 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Pfam PF09334 tRNA synthetases class I (M) 3 406 3.0E-160 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 SUPERFAMILY SSF47323 396 561 5.42E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Gene3D G3DSA:1.10.730.10 339 579 1.3E-107 T 23-10-2018 TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 Gene3D G3DSA:3.40.50.620 4 314 4.4E-144 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1724 956fc20e98f7bf6febb84793add15d01 738 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_730 3c60e68453a6bd1c5b3ebe0a866ded0d 257 SMART SM00849 33 224 3.1E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_730 3c60e68453a6bd1c5b3ebe0a866ded0d 257 SUPERFAMILY SSF56281 17 241 1.16E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_730 3c60e68453a6bd1c5b3ebe0a866ded0d 257 Gene3D G3DSA:3.60.15.10 7 243 1.6E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_730 3c60e68453a6bd1c5b3ebe0a866ded0d 257 Pfam PF00753 Metallo-beta-lactamase superfamily 34 224 2.3E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_941 b8d92a0dface97f91047283c5fa93568 64 Hamap MF_00422 Protein translocase subunit SecE [secE]. 7 64 12.147 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_941 b8d92a0dface97f91047283c5fa93568 64 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 61 4.5E-21 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_941 b8d92a0dface97f91047283c5fa93568 64 Gene3D G3DSA:1.20.5.820 3 62 1.6E-24 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_941 b8d92a0dface97f91047283c5fa93568 64 SUPERFAMILY SSF103456 5 59 4.05E-20 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_941 b8d92a0dface97f91047283c5fa93568 64 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 12 40 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 SUPERFAMILY SSF57783 1 34 2.98E-6 T 23-10-2018 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 SUPERFAMILY SSF57783 50 109 1.63E-23 T 23-10-2018 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 2.2E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 SMART SM00440 69 108 8.0E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 SMART SM00661 2 56 5.3E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 4.4E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 Gene3D G3DSA:2.20.25.10 55 110 6.1E-28 T 23-10-2018 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 PIRSF PIRSF005586 1 110 1.6E-38 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 5.7E-39 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 TAM4_877 b8765c0f3880f9ae85ead5bcfcbafe56 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TAM4_1482 aaa1d20362c3aabb206d5ac58b1dcfec 391 SUPERFAMILY SSF64484 26 384 1.72E-104 T 23-10-2018 TAM4_1482 aaa1d20362c3aabb206d5ac58b1dcfec 391 Gene3D G3DSA:1.10.150.390 333 378 5.4E-23 T 23-10-2018 TAM4_1482 aaa1d20362c3aabb206d5ac58b1dcfec 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 1.9E-151 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1482 aaa1d20362c3aabb206d5ac58b1dcfec 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 40.989 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1482 aaa1d20362c3aabb206d5ac58b1dcfec 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 30 332 3.2E-56 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_135 9b700ea216681f1284743d612f375ce6 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 308 3.7E-127 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TAM4_135 9b700ea216681f1284743d612f375ce6 308 Pfam PF13353 4Fe-4S single cluster domain 18 104 9.3E-10 T 23-10-2018 TAM4_135 9b700ea216681f1284743d612f375ce6 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 43.78 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TAM4_135 9b700ea216681f1284743d612f375ce6 308 SUPERFAMILY SSF102114 3 303 8.11E-70 T 23-10-2018 TAM4_135 9b700ea216681f1284743d612f375ce6 308 SMART SM00729 12 232 1.7E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_135 9b700ea216681f1284743d612f375ce6 308 Gene3D G3DSA:3.20.20.70 1 306 5.5E-78 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_135 9b700ea216681f1284743d612f375ce6 308 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 18 29 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_135 9b700ea216681f1284743d612f375ce6 308 Pfam PF04055 Radical SAM superfamily 17 172 4.5E-33 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_135 9b700ea216681f1284743d612f375ce6 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 2.5E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 Hamap MF_01508 Replication factor C large subunit [rfcL]. 3 438 35.071 T 23-10-2018 IPR023935 Replication factor C, large subunit TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 Gene3D G3DSA:1.10.8.60 159 223 4.8E-10 T 23-10-2018 TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 SUPERFAMILY SSF52540 3 221 6.92E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 SMART SM00382 41 158 3.6E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 45 155 4.6E-16 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_70 0d7b3b54f1e5ad8e4d7a213915d3ca4c 498 Gene3D G3DSA:3.40.50.300 4 156 1.1E-38 T 23-10-2018 TAM4_807 a4aaae1b910b0d848946faa3b8ee13ac 142 SUPERFAMILY SSF51735 12 139 2.18E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_807 a4aaae1b910b0d848946faa3b8ee13ac 142 Pfam PF13380 CoA binding domain 23 137 6.6E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_807 a4aaae1b910b0d848946faa3b8ee13ac 142 Gene3D G3DSA:3.40.50.720 4 142 6.6E-48 T 23-10-2018 TAM4_807 a4aaae1b910b0d848946faa3b8ee13ac 142 SMART SM00881 18 111 5.8E-31 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 36.473 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 1.5E-67 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 PIRSF PIRSF003336 1 220 7.4E-95 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 Gene3D G3DSA:3.40.50.300 7 220 7.6E-58 T 23-10-2018 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 SUPERFAMILY SSF52540 2 220 2.41E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_85 b09116ae949142041fd8163dfe660ce4 221 PRINTS PR01874 DNA repair protein radA signature 11 39 4.7E-6 T 23-10-2018 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 PRINTS PR01874 DNA repair protein radA signature 190 216 4.7E-6 T 23-10-2018 TAM4_85 b09116ae949142041fd8163dfe660ce4 221 Pfam PF08423 Rad51 2 162 3.3E-27 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TAM4_172 b773f3d0c7aa6a513daa453486956661 62 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 4.0E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TAM4_172 b773f3d0c7aa6a513daa453486956661 62 SUPERFAMILY SSF47598 4 47 1.45E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TAM4_172 b773f3d0c7aa6a513daa453486956661 62 Gene3D G3DSA:1.10.1220.10 11 47 1.7E-9 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TAM4_647 7b1cb3503833d47490981d425b874eb4 443 SUPERFAMILY SSF161098 216 442 1.44E-50 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_647 7b1cb3503833d47490981d425b874eb4 443 Gene3D G3DSA:1.10.3720.10 199 433 5.9E-46 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_647 7b1cb3503833d47490981d425b874eb4 443 Gene3D G3DSA:1.10.3720.10 3 85 1.6E-7 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_647 7b1cb3503833d47490981d425b874eb4 443 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 242 432 9.9E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_647 7b1cb3503833d47490981d425b874eb4 443 SUPERFAMILY SSF161098 9 71 5.76E-7 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_315 4d09d05018afb199874e0ec3036ed4e3 269 Pfam PF14336 Domain of unknown function (DUF4392) 3 90 1.9E-14 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TAM4_315 4d09d05018afb199874e0ec3036ed4e3 269 Pfam PF14336 Domain of unknown function (DUF4392) 104 260 9.7E-48 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TAM4_315 4d09d05018afb199874e0ec3036ed4e3 269 Gene3D G3DSA:3.90.1640.20 1 269 1.6E-98 T 23-10-2018 TAM4_1814 54268e7c0c98bafe4ccebb3aff64c814 95 SUPERFAMILY SSF46785 2 92 3.46E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1814 54268e7c0c98bafe4ccebb3aff64c814 95 Pfam PF03551 Transcriptional regulator PadR-like family 11 78 2.2E-15 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TAM4_1814 54268e7c0c98bafe4ccebb3aff64c814 95 Gene3D G3DSA:1.10.10.10 1 94 2.0E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1217 4d4699814083186831af46e20da00d47 281 SUPERFAMILY SSF103481 187 275 1.83E-12 T 23-10-2018 TAM4_1217 4d4699814083186831af46e20da00d47 281 SUPERFAMILY SSF103481 41 143 6.41E-12 T 23-10-2018 TAM4_1217 4d4699814083186831af46e20da00d47 281 Pfam PF00892 EamA-like transporter family 7 139 2.9E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1217 4d4699814083186831af46e20da00d47 281 Pfam PF00892 EamA-like transporter family 149 273 3.7E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_2184 f18bf9c7c7a2e1c638f7ec5070587419 151 PIRSF PIRSF018748 1 151 4.8E-56 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TAM4_2184 f18bf9c7c7a2e1c638f7ec5070587419 151 Pfam PF10050 Predicted metal-binding protein (DUF2284) 6 136 4.1E-32 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 SUPERFAMILY SSF53850 1 201 4.59E-62 T 23-10-2018 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 Pfam PF01634 ATP phosphoribosyltransferase 46 198 5.4E-50 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 48.877 T 23-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 177 7.9E-61 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 Gene3D G3DSA:3.40.190.10 3 192 6.0E-65 T 23-10-2018 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TAM4_1676 94c6a37346ea01fbcf6ce37966f7df15 205 Gene3D G3DSA:3.40.190.10 86 170 6.0E-65 T 23-10-2018 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 Gene3D G3DSA:3.20.20.70 1 209 1.5E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.878 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 203 7.1E-49 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 203 2.8E-38 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 SUPERFAMILY SSF51366 2 209 1.51E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_217 25f81c32dc15f9467d7ab0419f64cff8 211 SMART SM00934 3 203 2.4E-61 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_876 e9597d6c573c0b16115b93b2707ba15a 441 Gene3D G3DSA:1.20.1530.20 7 418 2.6E-22 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_876 e9597d6c573c0b16115b93b2707ba15a 441 Pfam PF00999 Sodium/hydrogen exchanger family 13 414 4.6E-52 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_1179 bcc6108dd892608bde25427cf05dba7d 396 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 377 396 1.2E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1179 bcc6108dd892608bde25427cf05dba7d 396 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 133 186 3.0E-23 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain TAM4_1179 bcc6108dd892608bde25427cf05dba7d 396 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 24 395 6.1E-131 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein TAM4_873 61d8fa8ecee13e310dcae5c319e48d28 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 3.2E-19 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TAM4_1364 fff3e9d287dce031402a361418b97d5f 271 Pfam PF06508 Queuosine biosynthesis protein QueC 54 134 4.5E-9 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_1364 fff3e9d287dce031402a361418b97d5f 271 SUPERFAMILY SSF52402 35 204 1.83E-31 T 23-10-2018 TAM4_1364 fff3e9d287dce031402a361418b97d5f 271 Gene3D G3DSA:3.40.50.620 2 192 3.1E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1364 fff3e9d287dce031402a361418b97d5f 271 PIRSF PIRSF036668 1 271 2.7E-133 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 452 2.4E-192 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 Gene3D G3DSA:3.20.20.70 4 483 4.1E-201 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 SMART SM01240 13 470 2.7E-267 T 23-10-2018 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 SMART SM00116 102 149 1.3E-10 T 23-10-2018 IPR000644 CBS domain TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 SMART SM00116 159 207 6.5E-15 T 23-10-2018 IPR000644 CBS domain TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 SUPERFAMILY SSF51412 10 474 3.01E-113 T 23-10-2018 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 470 1.1E-150 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 PIRSF PIRSF000130 3 485 6.9E-197 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 291 303 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 483 80.55 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 SUPERFAMILY SSF54631 94 204 6.95E-33 T 23-10-2018 TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 Pfam PF00571 CBS domain 100 145 7.9E-12 T 23-10-2018 IPR000644 CBS domain TAM4_493 86ec6a7223135872963e2e9f2e52e813 485 Pfam PF00571 CBS domain 152 204 2.0E-15 T 23-10-2018 IPR000644 CBS domain TAM4_501 c13343f43d52ea9c6669cfaa8810e8bd 451 Gene3D G3DSA:3.40.50.10180 20 263 8.9E-156 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TAM4_501 c13343f43d52ea9c6669cfaa8810e8bd 451 Gene3D G3DSA:3.40.1480.10 264 427 8.9E-156 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TAM4_501 c13343f43d52ea9c6669cfaa8810e8bd 451 Pfam PF13660 Domain of unknown function (DUF4147) 4 239 2.4E-74 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TAM4_501 c13343f43d52ea9c6669cfaa8810e8bd 451 SUPERFAMILY SSF82544 4 430 2.88E-128 T 23-10-2018 TAM4_501 c13343f43d52ea9c6669cfaa8810e8bd 451 Pfam PF05161 MOFRL family 320 423 1.3E-34 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 SMART SM00852 4 179 2.6E-42 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 6.2E-26 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 Gene3D G3DSA:3.40.980.10 2 178 2.2E-55 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 39.076 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 Pfam PF00994 Probable molybdopterin binding domain 4 176 4.2E-36 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1716 e18eba77e48fb1f768a3fb4bc7298ff6 253 SUPERFAMILY SSF53218 1 204 5.63E-41 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 Gene3D G3DSA:3.10.20.30 314 388 2.3E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 7.8E-20 T 23-10-2018 IPR031662 GTP binding protein, second domain TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 Pfam PF01926 50S ribosome-binding GTPase 84 185 1.6E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 3.3E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 3.3E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 3.3E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 3.3E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 SUPERFAMILY SSF81271 309 386 6.02E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 SUPERFAMILY SSF52540 84 323 4.72E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 4.2E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_853 5d544d661fd3017a10dd200c8a5cbf29 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TAM4_1883 964e4f8ad56a8eb0cffa354f3230b2be 278 SMART SM00478 111 269 1.7E-20 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TAM4_1883 964e4f8ad56a8eb0cffa354f3230b2be 278 SUPERFAMILY SSF48150 90 268 2.79E-34 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TAM4_1883 964e4f8ad56a8eb0cffa354f3230b2be 278 Gene3D G3DSA:1.10.340.30 102 215 1.4E-25 T 23-10-2018 TAM4_1883 964e4f8ad56a8eb0cffa354f3230b2be 278 Gene3D G3DSA:1.10.1670.10 217 274 2.8E-9 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TAM4_1883 964e4f8ad56a8eb0cffa354f3230b2be 278 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 107 251 2.9E-13 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TAM4_1239 8ba9d6b737e9c61d4889f115603e3c4c 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.1E-13 T 23-10-2018 TAM4_1239 8ba9d6b737e9c61d4889f115603e3c4c 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 262 1.1E-13 T 23-10-2018 TAM4_1239 8ba9d6b737e9c61d4889f115603e3c4c 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 214 235 1.1E-13 T 23-10-2018 TAM4_1239 8ba9d6b737e9c61d4889f115603e3c4c 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 1.1E-13 T 23-10-2018 TAM4_1239 8ba9d6b737e9c61d4889f115603e3c4c 478 Pfam PF00361 Proton-conducting membrane transporter 135 410 6.5E-33 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.3E-19 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 SUPERFAMILY SSF46689 5 66 6.98E-19 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.5E-11 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.5E-11 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TAM4_1196 80a2ae8e46406660b2a7240b8e167f93 199 Gene3D G3DSA:1.10.357.10 3 195 8.8E-28 T 23-10-2018 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 Gene3D G3DSA:1.20.1260.30 13 159 1.8E-8 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 Pfam PF02384 N-6 DNA Methylase 166 484 1.1E-112 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 Gene3D G3DSA:3.40.50.150 167 468 3.6E-97 T 23-10-2018 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 304 7.0E-12 T 23-10-2018 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 213 227 7.0E-12 T 23-10-2018 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 7.0E-12 T 23-10-2018 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 295 301 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 SUPERFAMILY SSF53335 23 518 9.57E-126 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1847 247e2f4a37ba08d0c9b00e6a3daf4a0c 523 Pfam PF12161 HsdM N-terminal domain 24 157 2.2E-19 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TAM4_2324 eb58bbed66179b136e4df440bce2e37b 69 Gene3D G3DSA:2.30.30.240 3 69 2.9E-6 T 23-10-2018 TAM4_2324 eb58bbed66179b136e4df440bce2e37b 69 Pfam PF05239 PRC-barrel domain 2 68 7.6E-14 T 23-10-2018 IPR027275 PRC-barrel domain TAM4_2324 eb58bbed66179b136e4df440bce2e37b 69 SUPERFAMILY SSF50346 1 66 3.61E-14 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TAM4_1043 e9c24aacf33bd83246a7ca25a67d5f56 143 Gene3D G3DSA:3.30.300.20 8 143 7.2E-31 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_1043 e9c24aacf33bd83246a7ca25a67d5f56 143 Pfam PF02566 OsmC-like protein 36 138 3.6E-22 T 23-10-2018 IPR003718 OsmC/Ohr family TAM4_1043 e9c24aacf33bd83246a7ca25a67d5f56 143 SUPERFAMILY SSF82784 6 139 1.31E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 Pfam PF13247 4Fe-4S dicluster domain 43 136 1.2E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 SUPERFAMILY SSF54862 4 141 1.99E-52 T 23-10-2018 TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 Pfam PF12800 4Fe-4S binding domain 13 27 0.0028 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 Gene3D G3DSA:3.30.70.20 36 167 6.3E-42 T 23-10-2018 TAM4_1130 2501bb3e3443cafc9d6b61f7b8d78f73 168 Gene3D G3DSA:3.30.70.20 5 35 4.7E-6 T 23-10-2018 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 200 1.3E-29 T 23-10-2018 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 1.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 1.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 196 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 Gene3D G3DSA:1.10.150.240 15 100 2.5E-63 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 201 2.6E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 5.2E-56 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 SUPERFAMILY SSF56784 1 230 2.94E-52 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_588 9f75df6fc36a4bd72b8a35f7d8e0fb01 234 Gene3D G3DSA:3.40.50.1000 3 222 2.5E-63 T 23-10-2018 IPR023214 HAD superfamily TAM4_1887 95a21fba98568002fe14c943f2eb9dd8 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 5 253 3.7E-63 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TAM4_1887 95a21fba98568002fe14c943f2eb9dd8 255 PIRSF PIRSF005902 2 255 1.3E-52 T 23-10-2018 IPR001130 TatD family GO:0016788 TAM4_1887 95a21fba98568002fe14c943f2eb9dd8 255 Gene3D G3DSA:3.20.20.140 1 255 1.2E-59 T 23-10-2018 TAM4_1887 95a21fba98568002fe14c943f2eb9dd8 255 SUPERFAMILY SSF51556 5 254 2.64E-53 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_1887 95a21fba98568002fe14c943f2eb9dd8 255 Pfam PF01026 TatD related DNase 6 252 2.9E-54 T 23-10-2018 IPR001130 TatD family GO:0016788 TAM4_1386 4d2684419741cbada7406598b142ffc0 334 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 60 221 4.1E-26 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_1386 4d2684419741cbada7406598b142ffc0 334 Gene3D G3DSA:3.40.50.970 15 100 9.2E-12 T 23-10-2018 TAM4_1386 4d2684419741cbada7406598b142ffc0 334 Gene3D G3DSA:3.40.50.970 101 326 5.3E-69 T 23-10-2018 TAM4_1386 4d2684419741cbada7406598b142ffc0 334 SUPERFAMILY SSF52518 14 321 2.81E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_2182 c07c3721469c9ccb702d529d5f85c589 386 Pfam PF04412 Protein of unknown function (DUF521) 1 382 1.3E-146 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative TAM4_296 01d228abf4826e58cad403ecc5dc66e5 242 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 146 1.1E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_296 01d228abf4826e58cad403ecc5dc66e5 242 Gene3D G3DSA:3.40.50.700 1 160 2.3E-33 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TAM4_296 01d228abf4826e58cad403ecc5dc66e5 242 SUPERFAMILY SSF56770 2 206 1.96E-42 T 23-10-2018 TAM4_1793 16c653f74f05115b2db60825bcf331f2 248 SUPERFAMILY SSF51695 6 214 1.94E-61 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TAM4_1793 16c653f74f05115b2db60825bcf331f2 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 216 5.9E-35 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TAM4_1793 16c653f74f05115b2db60825bcf331f2 248 Gene3D G3DSA:3.20.20.190 1 248 2.7E-96 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TAM4_1142 b92853f1e1984d7eab04270a3178ad1f 284 Pfam PF13559 Domain of unknown function (DUF4129) 210 274 1.8E-8 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 TAM4_886 74ca372530625cb8a6e6286d25d8df92 56 SUPERFAMILY SSF57829 10 56 2.56E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_886 74ca372530625cb8a6e6286d25d8df92 56 Pfam PF01599 Ribosomal protein S27a 11 52 2.5E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TAM4_886 74ca372530625cb8a6e6286d25d8df92 56 SMART SM01402 10 52 1.2E-24 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TAM4_886 74ca372530625cb8a6e6286d25d8df92 56 Gene3D G3DSA:2.20.25.660 1 55 1.3E-20 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TAM4_886 74ca372530625cb8a6e6286d25d8df92 56 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 10 55 19.566 T 23-10-2018 IPR022845 Ribosomal protein S27ae TAM4_2430 98eb869a881c66b27e4afafd2f7220f0 117 Pfam PF07883 Cupin domain 39 98 3.7E-13 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TAM4_2430 98eb869a881c66b27e4afafd2f7220f0 117 Gene3D G3DSA:2.60.120.10 5 116 5.5E-30 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TAM4_2430 98eb869a881c66b27e4afafd2f7220f0 117 SUPERFAMILY SSF51182 9 105 2.49E-25 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TAM4_351 621b42ada02749772a1c4fb75469917e 118 SUPERFAMILY SSF102462 3 118 2.96E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TAM4_351 621b42ada02749772a1c4fb75469917e 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 30.125 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 TAM4_351 621b42ada02749772a1c4fb75469917e 118 Gene3D G3DSA:3.40.1490.10 1 118 8.6E-48 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TAM4_351 621b42ada02749772a1c4fb75469917e 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 6.5E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TAM4_351 621b42ada02749772a1c4fb75469917e 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 1.9E-42 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 Gene3D G3DSA:3.40.50.1100 11 236 6.9E-179 T 23-10-2018 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 PIRSF PIRSF001413 6 430 2.8E-157 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.567 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 Gene3D G3DSA:3.40.50.1100 10 417 6.9E-179 T 23-10-2018 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 1.2E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TAM4_288 5c957cc75481faa369b7ee61483218e8 442 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 3.8E-221 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TAM4_288 5c957cc75481faa369b7ee61483218e8 442 SUPERFAMILY SSF53686 27 423 6.02E-112 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TAM4_288 5c957cc75481faa369b7ee61483218e8 442 PIRSF PIRSF500824 1 433 2.0E-215 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 PIRSF PIRSF002741 211 422 4.4E-10 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 PIRSF PIRSF002741 106 203 0.0014 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 PIRSF PIRSF002741 434 712 1.4E-55 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 264 700 8.6E-69 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 SUPERFAMILY SSF53850 218 699 1.09E-87 T 23-10-2018 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 Gene3D G3DSA:3.10.105.10 542 711 7.2E-44 T 23-10-2018 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 SUPERFAMILY SSF53850 122 201 1.01E-6 T 23-10-2018 TAM4_662 925bef9b6a0bac2fbd91d2892bc92755 712 ProSitePatterns PS00018 EF-hand calcium-binding domain. 331 343 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site TAM4_1419 f4d4b5aae32c4b7b93cf0dd284a2150d 664 Pfam PF00361 Proton-conducting membrane transporter 124 425 5.9E-49 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1419 f4d4b5aae32c4b7b93cf0dd284a2150d 664 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 2.4E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1419 f4d4b5aae32c4b7b93cf0dd284a2150d 664 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 230 254 2.4E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1419 f4d4b5aae32c4b7b93cf0dd284a2150d 664 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 2.4E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1312 7b1d4f91f53cd702027b3aa137a3d03c 215 SUPERFAMILY SSF56112 8 157 1.56E-15 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_2063 2044d43659f430df0624f0847d13e096 271 Gene3D G3DSA:3.40.50.300 4 258 1.3E-63 T 23-10-2018 TAM4_2063 2044d43659f430df0624f0847d13e096 271 SMART SM00382 35 229 2.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2063 2044d43659f430df0624f0847d13e096 271 Pfam PF00005 ABC transporter 26 172 3.3E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2063 2044d43659f430df0624f0847d13e096 271 SUPERFAMILY SSF52540 11 234 1.55E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2063 2044d43659f430df0624f0847d13e096 271 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_969 293e9fc44e4b328056606da95b324802 129 SMART SM00670 1 120 2.0E-6 T 23-10-2018 IPR002716 PIN domain TAM4_969 293e9fc44e4b328056606da95b324802 129 SUPERFAMILY SSF88723 1 125 1.09E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_969 293e9fc44e4b328056606da95b324802 129 Gene3D G3DSA:3.40.50.1010 1 127 3.8E-20 T 23-10-2018 TAM4_969 293e9fc44e4b328056606da95b324802 129 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 128 11.19 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_969 293e9fc44e4b328056606da95b324802 129 Pfam PF01850 PIN domain 4 121 7.0E-20 T 23-10-2018 IPR002716 PIN domain TAM4_1561 78521fdebd3662eba91486c528342793 446 Gene3D G3DSA:1.10.275.10 1 100 1.5E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal TAM4_1561 78521fdebd3662eba91486c528342793 446 Gene3D G3DSA:1.10.40.30 360 445 2.1E-24 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 Gene3D G3DSA:1.20.200.10 101 359 3.6E-94 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TAM4_1561 78521fdebd3662eba91486c528342793 446 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 5.5E-21 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_1561 78521fdebd3662eba91486c528342793 446 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 3.2E-188 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_1561 78521fdebd3662eba91486c528342793 446 SMART SM00998 360 439 1.1E-34 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TAM4_1561 78521fdebd3662eba91486c528342793 446 SUPERFAMILY SSF48557 4 444 2.51E-136 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 1.2E-25 T 23-10-2018 IPR000362 Fumarate lyase family TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 1.2E-25 T 23-10-2018 IPR000362 Fumarate lyase family TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 1.2E-25 T 23-10-2018 IPR000362 Fumarate lyase family TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 1.2E-25 T 23-10-2018 IPR000362 Fumarate lyase family TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 4.2E-11 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 4.2E-11 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 4.2E-11 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 4.2E-11 T 23-10-2018 TAM4_1561 78521fdebd3662eba91486c528342793 446 Pfam PF00206 Lyase 13 295 3.1E-57 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal TAM4_1989 62f7550d8c40c4ec8eaf94cdcaaccf2c 289 SUPERFAMILY SSF53807 2 277 2.94E-17 T 23-10-2018 TAM4_1989 62f7550d8c40c4ec8eaf94cdcaaccf2c 289 Gene3D G3DSA:3.40.50.1980 2 117 2.3E-5 T 23-10-2018 TAM4_1989 62f7550d8c40c4ec8eaf94cdcaaccf2c 289 Gene3D G3DSA:3.40.50.1980 120 252 7.5E-6 T 23-10-2018 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 Pfam PF01470 Pyroglutamyl peptidase 1 196 7.5E-74 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 SUPERFAMILY SSF53182 1 198 1.44E-69 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 Gene3D G3DSA:3.40.630.20 1 199 1.1E-75 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 195 2.3E-71 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.22 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 2.3E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 2.3E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 2.3E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 2.3E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 2.3E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1439 bec78b5f3d3ebb0ecba98fd674114f43 200 PIRSF PIRSF015592 1 200 6.4E-78 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TAM4_1295 4cdee8452d63f6fd66d6edafe8427c76 191 SMART SM00418 11 105 9.0E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1295 4cdee8452d63f6fd66d6edafe8427c76 191 Gene3D G3DSA:1.10.20.10 90 191 1.6E-54 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_1295 4cdee8452d63f6fd66d6edafe8427c76 191 SUPERFAMILY SSF46785 1 165 2.48E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1295 4cdee8452d63f6fd66d6edafe8427c76 191 Gene3D G3DSA:1.10.10.10 1 89 3.1E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1295 4cdee8452d63f6fd66d6edafe8427c76 191 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 6.6E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1768 6a02d0e210c7fc8426c9ddbf9ac74ff7 288 SUPERFAMILY SSF53474 24 288 4.81E-55 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_1768 6a02d0e210c7fc8426c9ddbf9ac74ff7 288 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 79 175 5.5E-15 T 23-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TAM4_1768 6a02d0e210c7fc8426c9ddbf9ac74ff7 288 Gene3D G3DSA:3.40.50.1820 42 288 1.8E-47 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_330 954eab2017427a304d18e06e21299146 230 SUPERFAMILY SSF52540 5 217 2.11E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_330 954eab2017427a304d18e06e21299146 230 SMART SM00382 32 206 7.2E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_330 954eab2017427a304d18e06e21299146 230 Pfam PF00005 ABC transporter 24 160 1.9E-19 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_330 954eab2017427a304d18e06e21299146 230 Gene3D G3DSA:3.40.50.300 1 226 2.0E-43 T 23-10-2018 TAM4_642 e28e3b767d6e33365b85a10f5f27969e 350 Pfam PF13412 Winged helix-turn-helix DNA-binding 295 335 8.3E-6 T 23-10-2018 TAM4_642 e28e3b767d6e33365b85a10f5f27969e 350 Gene3D G3DSA:1.10.10.10 268 347 5.8E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_642 e28e3b767d6e33365b85a10f5f27969e 350 SUPERFAMILY SSF46785 275 341 7.58E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_386 443a2abf24e75162298cc0fa479cb3d0 122 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 79 1.1E-11 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TAM4_386 443a2abf24e75162298cc0fa479cb3d0 122 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 83 4.3E-12 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TAM4_386 443a2abf24e75162298cc0fa479cb3d0 122 PIRSF PIRSF018867 1 119 2.0E-33 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit TAM4_1983 bda851afc2e4c7095916822aed1ef269 173 Gene3D G3DSA:1.20.1260.10 1 169 1.6E-54 T 23-10-2018 IPR012347 Ferritin-like TAM4_1983 bda851afc2e4c7095916822aed1ef269 173 SUPERFAMILY SSF47240 1 160 2.92E-60 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1983 bda851afc2e4c7095916822aed1ef269 173 Pfam PF00210 Ferritin-like domain 7 142 1.3E-43 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 217 41.373 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 Gene3D G3DSA:3.40.50.150 1 219 6.4E-94 T 23-10-2018 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 13 214 1.1E-60 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 136 151 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 213 4.8E-66 T 23-10-2018 TAM4_1729 a03fdffb8a74c29b0a5954db834a9280 219 SUPERFAMILY SSF53335 5 216 7.41E-56 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_2172 968f59c108e414409bf2b2e3b966119d 153 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 7.2E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TAM4_2172 968f59c108e414409bf2b2e3b966119d 153 SUPERFAMILY SSF46785 10 138 1.91E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2172 968f59c108e414409bf2b2e3b966119d 153 Gene3D G3DSA:1.10.10.10 1 104 9.1E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 SMART SM00881 9 103 4.0E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 SUPERFAMILY SSF52210 295 454 3.01E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 Gene3D G3DSA:3.40.50.720 5 132 7.4E-47 T 23-10-2018 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 153 290 8.9E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 SUPERFAMILY SSF51735 6 133 1.23E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 Pfam PF13380 CoA binding domain 14 138 8.2E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 Gene3D G3DSA:3.40.50.261 293 461 9.7E-67 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 Gene3D G3DSA:3.40.50.261 133 292 9.9E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1034 d0df80003fbd57ba59fff88e372507e3 461 SUPERFAMILY SSF52210 135 291 4.45E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 SMART SM00382 33 222 6.8E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 Gene3D G3DSA:3.40.50.300 1 243 1.4E-57 T 23-10-2018 TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 SUPERFAMILY SSF52540 261 495 4.24E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 Pfam PF00005 ABC transporter 279 434 1.3E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 SUPERFAMILY SSF52540 6 232 7.67E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 Gene3D G3DSA:3.40.50.300 259 501 2.2E-42 T 23-10-2018 TAM4_1688 e65c31dbb35acaaefe545ef19456da84 511 Pfam PF00005 ABC transporter 24 174 3.9E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1735 ae3c65c95f502bc614810d347b47f4ed 287 SUPERFAMILY SSF56281 16 285 7.85E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1735 ae3c65c95f502bc614810d347b47f4ed 287 Gene3D G3DSA:3.40.50.10890 128 169 4.4E-23 T 23-10-2018 TAM4_1735 ae3c65c95f502bc614810d347b47f4ed 287 Gene3D G3DSA:3.60.15.10 50 127 4.4E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 Pfam PF01138 3' exoribonuclease family, domain 1 32 167 6.5E-29 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 Pfam PF03725 3' exoribonuclease family, domain 2 192 256 2.7E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 SUPERFAMILY SSF54211 13 215 1.97E-55 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 SUPERFAMILY SSF55666 187 269 8.61E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 Gene3D G3DSA:3.30.230.70 1 271 2.7E-90 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_195 a5a29a2f3cdcd434af39dd2e0ef7d1a5 273 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 3 268 46.24 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 TAM4_786 f4855e1037e04bc147c865a9d9db1477 246 SMART SM00382 26 209 1.5E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_786 f4855e1037e04bc147c865a9d9db1477 246 Pfam PF00005 ABC transporter 17 161 5.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_786 f4855e1037e04bc147c865a9d9db1477 246 Gene3D G3DSA:3.40.50.300 1 240 9.4E-67 T 23-10-2018 TAM4_786 f4855e1037e04bc147c865a9d9db1477 246 SUPERFAMILY SSF52540 2 219 1.6E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_786 f4855e1037e04bc147c865a9d9db1477 246 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 199 3.3E-14 T 23-10-2018 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 SUPERFAMILY SSF56784 1 228 2.25E-34 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 Gene3D G3DSA:3.40.50.1000 2 215 3.3E-64 T 23-10-2018 IPR023214 HAD superfamily TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 9.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 9.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 9.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 9.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 134 193 2.1E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_1690 f1bf5f2680aa4a80342cf84faea4c7cd 233 Gene3D G3DSA:1.10.150.400 14 92 3.3E-64 T 23-10-2018 TAM4_1999 a2a1358af9f9698bb55be518a382f2a8 258 SUPERFAMILY SSF109604 48 170 2.9E-9 T 23-10-2018 TAM4_1999 a2a1358af9f9698bb55be518a382f2a8 258 SMART SM00471 48 181 0.0038 T 23-10-2018 IPR003607 HD/PDEase domain TAM4_1999 a2a1358af9f9698bb55be518a382f2a8 258 Gene3D G3DSA:1.10.3210.10 12 199 8.8E-9 T 23-10-2018 TAM4_1399 37676fe876175fdae527da0903a7d00c 487 Gene3D G3DSA:3.50.50.60 420 460 4.6E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1399 37676fe876175fdae527da0903a7d00c 487 Gene3D G3DSA:3.50.50.60 3 96 2.9E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1399 37676fe876175fdae527da0903a7d00c 487 Gene3D G3DSA:3.50.50.60 137 236 3.7E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1399 37676fe876175fdae527da0903a7d00c 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.0E-11 T 23-10-2018 TAM4_1399 37676fe876175fdae527da0903a7d00c 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 2.0E-11 T 23-10-2018 TAM4_1399 37676fe876175fdae527da0903a7d00c 487 PIRSF PIRSF038984 4 90 1.5E-9 T 23-10-2018 IPR028348 FAD dependent protein TAM4_1399 37676fe876175fdae527da0903a7d00c 487 PIRSF PIRSF038984 135 467 9.6E-26 T 23-10-2018 IPR028348 FAD dependent protein TAM4_1399 37676fe876175fdae527da0903a7d00c 487 Pfam PF03486 HI0933-like protein 11 47 1.4E-6 T 23-10-2018 TAM4_1399 37676fe876175fdae527da0903a7d00c 487 SUPERFAMILY SSF51905 11 463 1.69E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_2113 ec2602791bcc2fdb056e576c7cdb850a 265 Pfam PF14378 PAP2 superfamily 80 218 6.2E-11 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 TAM4_2113 ec2602791bcc2fdb056e576c7cdb850a 265 SUPERFAMILY SSF48317 73 222 8.17E-6 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 SUPERFAMILY SSF51011 580 633 1.49E-6 T 23-10-2018 TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 SUPERFAMILY SSF81296 21 84 3.4E-9 T 23-10-2018 IPR014756 Immunoglobulin E-set TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Gene3D G3DSA:2.60.40.10 105 198 2.6E-27 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Gene3D G3DSA:2.60.40.1180 577 634 9.6E-7 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Gene3D G3DSA:2.60.40.10 1 104 1.6E-19 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Gene3D G3DSA:3.20.20.80 199 576 4.2E-134 T 23-10-2018 TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Pfam PF00128 Alpha amylase, catalytic domain 231 538 1.3E-53 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 SMART SM00642 211 571 1.5E-89 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 SUPERFAMILY SSF81296 109 185 1.5E-8 T 23-10-2018 IPR014756 Immunoglobulin E-set TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 109 181 6.3E-5 T 23-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 TAM4_475 7c4b7f819bdea7b54a7c600a5d2395e0 638 SUPERFAMILY SSF51445 200 578 2.2E-93 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Pfam PF00814 Glycoprotease family 611 740 9.7E-7 T 23-10-2018 IPR000905 Gcp-like domain TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Pfam PF01300 Telomere recombination 208 383 2.6E-46 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Gene3D G3DSA:3.30.420.360 383 755 6.1E-105 T 23-10-2018 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 755 8.0E-265 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Pfam PF00708 Acylphosphatase 4 88 1.2E-24 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Gene3D G3DSA:3.90.870.50 6 362 9.5E-145 T 23-10-2018 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 SUPERFAMILY SSF53067 400 737 1.85E-7 T 23-10-2018 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Pfam PF07503 HypF finger 158 191 9.9E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Pfam PF07503 HypF finger 108 141 1.6E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Gene3D G3DSA:3.30.110.120 252 371 9.5E-145 T 23-10-2018 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 Gene3D G3DSA:3.30.420.350 486 743 6.1E-105 T 23-10-2018 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 SUPERFAMILY SSF55821 175 390 1.07E-44 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 PIRSF PIRSF006256 1 765 4.1E-285 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TAM4_1253 586ad7bb8a0a8d4ae7a497202d57a806 772 SUPERFAMILY SSF54975 1 88 1.33E-26 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TAM4_1303 8288dd08a510b1ea470a10da6f649a9d 362 Pfam PF13424 Tetratricopeptide repeat 71 141 1.5E-7 T 23-10-2018 TAM4_1303 8288dd08a510b1ea470a10da6f649a9d 362 SUPERFAMILY SSF48452 15 188 1.52E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1303 8288dd08a510b1ea470a10da6f649a9d 362 Gene3D G3DSA:1.25.40.10 1 358 1.9E-72 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 Gene3D G3DSA:3.10.450.80 1 93 5.5E-31 T 23-10-2018 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 25.038 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 SUPERFAMILY SSF57829 1 93 4.76E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 1.0E-39 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1718 3a4f5c54c6e7d2196db902daa77906b2 94 Pfam PF00935 Ribosomal protein L44 16 92 5.4E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2087 3355936e7a72ea0cb7bd7dfbb2e5b600 359 SUPERFAMILY SSF102114 39 209 1.44E-12 T 23-10-2018 TAM4_2087 3355936e7a72ea0cb7bd7dfbb2e5b600 359 Gene3D G3DSA:3.20.20.70 39 217 7.2E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_2087 3355936e7a72ea0cb7bd7dfbb2e5b600 359 Pfam PF04459 Protein of unknown function (DUF512) 250 332 5.8E-11 T 23-10-2018 IPR007549 Domain of unknown function DUF512 TAM4_1799 c02cc29a3fc2024ecceb404543e7d45c 146 Gene3D G3DSA:2.30.130.60 87 144 3.1E-10 T 23-10-2018 TAM4_1799 c02cc29a3fc2024ecceb404543e7d45c 146 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 96 142 4.6E-15 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 4.3E-37 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Gene3D G3DSA:3.40.50.300 1 212 8.0E-88 T 23-10-2018 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 4.6E-59 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 SUPERFAMILY SSF50447 213 315 1.52E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.321 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 SUPERFAMILY SSF52540 3 236 1.32E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 6.7E-18 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 5.3E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Gene3D G3DSA:2.40.30.10 216 310 1.5E-41 T 23-10-2018 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 SUPERFAMILY SSF50465 321 424 6.83E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TAM4_769 026ad771ceef98e1364a5be128bd827d 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 8.4E-215 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TAM4_769 026ad771ceef98e1364a5be128bd827d 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.6E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.6E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.6E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.6E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_769 026ad771ceef98e1364a5be128bd827d 428 Gene3D G3DSA:2.40.30.10 320 425 1.5E-40 T 23-10-2018 TAM4_136 f447bdde32f876e98b4dce0ad990f811 136 Pfam PF01894 Uncharacterised protein family UPF0047 19 133 6.2E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_136 f447bdde32f876e98b4dce0ad990f811 136 PIRSF PIRSF004681 1 136 8.6E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_136 f447bdde32f876e98b4dce0ad990f811 136 SUPERFAMILY SSF111038 2 136 3.79E-43 T 23-10-2018 IPR035917 YjbQ-like superfamily TAM4_136 f447bdde32f876e98b4dce0ad990f811 136 Gene3D G3DSA:2.60.120.460 1 136 2.2E-48 T 23-10-2018 IPR035917 YjbQ-like superfamily TAM4_136 f447bdde32f876e98b4dce0ad990f811 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 136 1.5E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 Pfam PF01597 Glycine cleavage H-protein 13 133 3.3E-51 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 SUPERFAMILY SSF51230 10 133 5.89E-43 T 23-10-2018 IPR011053 Single hybrid motif TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 3.1E-48 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 Gene3D G3DSA:2.40.50.100 2 132 1.5E-53 T 23-10-2018 TAM4_835 dc6b7bbb1286a6d6d0bd8662e926d9b1 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 42.474 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TAM4_2166 ddeddc98492b7258d309bec43234049b 179 Pfam PF06197 Protein of unknown function (DUF998) 11 173 2.2E-26 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TAM4_1569 ca576cc3bd450d6f5a0403ad18ad84b0 305 Gene3D G3DSA:3.40.50.300 1 236 3.0E-58 T 23-10-2018 TAM4_1569 ca576cc3bd450d6f5a0403ad18ad84b0 305 Pfam PF00005 ABC transporter 17 167 1.5E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1569 ca576cc3bd450d6f5a0403ad18ad84b0 305 SUPERFAMILY SSF52540 1 229 9.13E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1569 ca576cc3bd450d6f5a0403ad18ad84b0 305 SMART SM00382 26 229 1.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1569 ca576cc3bd450d6f5a0403ad18ad84b0 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 SUPERFAMILY SSF53187 9 382 7.18E-87 T 23-10-2018 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 370 3.3E-118 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 SUPERFAMILY SSF55031 182 287 2.09E-30 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 Pfam PF01546 Peptidase family M20/M25/M40 70 378 1.6E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 Gene3D G3DSA:3.30.70.360 178 292 5.6E-144 T 23-10-2018 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 PIRSF PIRSF005962 1 383 1.6E-130 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 Gene3D G3DSA:3.40.630.10 16 367 5.6E-144 T 23-10-2018 TAM4_2024 d98601d8ec6bd986a0da0aacaeb069a8 383 Pfam PF07687 Peptidase dimerisation domain 187 277 1.3E-10 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 Gene3D G3DSA:3.40.50.720 3 354 3.2E-137 T 23-10-2018 TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 109 211 1.9E-10 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 Gene3D G3DSA:3.30.360.10 216 319 3.2E-137 T 23-10-2018 TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 SUPERFAMILY SSF55347 211 316 7.59E-28 T 23-10-2018 TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 PIRSF PIRSF015578 1 380 7.1E-96 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 SUPERFAMILY SSF51735 1 378 2.1E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_329 960871a1ab277c49b858d71795d5f8f0 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 1.7E-19 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TAM4_1679 4d3afaf91ae900bc78279a20a9dec6de 251 Gene3D G3DSA:1.25.10.10 1 250 4.0E-76 T 23-10-2018 IPR011989 Armadillo-like helical TAM4_1679 4d3afaf91ae900bc78279a20a9dec6de 251 SUPERFAMILY SSF48371 21 243 9.46E-26 T 23-10-2018 IPR016024 Armadillo-type fold TAM4_1119 a4f47e13bd3979faff462e8a47477f29 315 Pfam PF13186 Iron-sulfur cluster-binding domain 230 287 2.1E-6 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_1119 a4f47e13bd3979faff462e8a47477f29 315 Gene3D G3DSA:3.20.20.70 80 314 8.7E-10 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1119 a4f47e13bd3979faff462e8a47477f29 315 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 227 308 5.9E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_1119 a4f47e13bd3979faff462e8a47477f29 315 SUPERFAMILY SSF102114 71 292 4.32E-11 T 23-10-2018 TAM4_1740 6153a61719752a78e0e207b5430471f1 431 Pfam PF13360 PQQ-like domain 191 395 2.2E-8 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SUPERFAMILY SSF50998 218 396 1.22E-14 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_1740 6153a61719752a78e0e207b5430471f1 431 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 403 421 3.3E-5 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1740 6153a61719752a78e0e207b5430471f1 431 Gene3D G3DSA:2.130.10.10 171 404 8.5E-19 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SMART SM00564 235 270 290.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SMART SM00564 318 365 69.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SMART SM00564 188 228 43.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SMART SM00564 277 311 37.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_1740 6153a61719752a78e0e207b5430471f1 431 SMART SM00564 46 90 560.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_1232 8fc75da53fb085ee41b5490862e3f4cd 304 Pfam PF13412 Winged helix-turn-helix DNA-binding 152 194 2.0E-6 T 23-10-2018 TAM4_1232 8fc75da53fb085ee41b5490862e3f4cd 304 Gene3D G3DSA:1.10.10.10 153 198 7.0E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1232 8fc75da53fb085ee41b5490862e3f4cd 304 SUPERFAMILY SSF46785 150 227 8.2E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_646 43ae4b51e16c2e991b833471e3e92ab1 106 SUPERFAMILY SSF117782 1 105 1.24E-38 T 23-10-2018 IPR035439 UPF0145 domain superfamily TAM4_646 43ae4b51e16c2e991b833471e3e92ab1 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 26.045 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TAM4_646 43ae4b51e16c2e991b833471e3e92ab1 106 Gene3D G3DSA:3.30.110.70 1 106 1.6E-35 T 23-10-2018 TAM4_646 43ae4b51e16c2e991b833471e3e92ab1 106 Pfam PF01906 Putative heavy-metal-binding 1 103 9.0E-39 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 1.3E-128 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 SUPERFAMILY SSF100950 12 351 1.88E-115 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 Pfam PF01008 Initiation factor 2 subunit family 55 343 6.5E-83 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 Gene3D G3DSA:1.20.120.420 11 156 1.7E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 Gene3D G3DSA:3.40.50.10470 159 356 5.7E-60 T 23-10-2018 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 1.9E-115 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1825 cb4672f81cd674db8831b812dcee302d 357 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 40.114 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TAM4_1784 a9fda8d76615813ba0c0b63f198306af 202 Gene3D G3DSA:3.40.1280.10 1 199 3.5E-69 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TAM4_1784 a9fda8d76615813ba0c0b63f198306af 202 SUPERFAMILY SSF75217 1 197 2.96E-66 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_1784 a9fda8d76615813ba0c0b63f198306af 202 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 2.3E-50 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TAM4_1784 a9fda8d76615813ba0c0b63f198306af 202 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 199 36.313 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TAM4_1850 a3f825e771ba59802b5d52c6cf29b4c3 356 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 31 338 1.2E-88 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TAM4_1850 a3f825e771ba59802b5d52c6cf29b4c3 356 Gene3D G3DSA:3.40.190.10 136 338 6.7E-109 T 23-10-2018 TAM4_1850 a3f825e771ba59802b5d52c6cf29b4c3 356 Pfam PF13343 Bacterial extracellular solute-binding protein 84 328 1.8E-26 T 23-10-2018 TAM4_1850 a3f825e771ba59802b5d52c6cf29b4c3 356 Gene3D G3DSA:3.40.190.10 35 314 6.7E-109 T 23-10-2018 TAM4_1850 a3f825e771ba59802b5d52c6cf29b4c3 356 SUPERFAMILY SSF53850 30 338 1.32E-67 T 23-10-2018 TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 SUPERFAMILY SSF52540 1 231 1.04E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 1.0E-155 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 Gene3D G3DSA:3.40.50.880 247 393 1.6E-17 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 Gene3D G3DSA:3.40.50.300 2 240 3.0E-46 T 23-10-2018 TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 3.2E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 480 158.609 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 SUPERFAMILY SSF52317 192 369 1.83E-30 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_683 a8080cc12239051a8bc1d339811c36a6 480 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 4.2E-50 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TAM4_155 9012c7eb42361c8db0705713f701c6d7 263 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 254 6.7E-14 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TAM4_155 9012c7eb42361c8db0705713f701c6d7 263 SUPERFAMILY SSF53213 6 259 9.29E-25 T 23-10-2018 TAM4_155 9012c7eb42361c8db0705713f701c6d7 263 Gene3D G3DSA:3.40.830.10 1 262 3.2E-70 T 23-10-2018 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 SUPERFAMILY SSF50331 251 348 1.08E-11 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 Gene3D G3DSA:2.40.50.940 228 347 1.7E-9 T 23-10-2018 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 336 4.6E-109 T 23-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 SUPERFAMILY SSF52540 4 247 1.5E-91 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 Gene3D G3DSA:3.40.50.300 4 227 1.8E-66 T 23-10-2018 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 SMART SM00382 28 217 1.8E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 Gene3D G3DSA:2.40.50.140 290 346 1.7E-9 T 23-10-2018 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 Pfam PF00005 ABC transporter 20 167 2.6E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_600 3429f75c52465f3a4efba652df2b3dde 355 Pfam PF08402 TOBE domain 284 349 3.5E-9 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TAM4_728 bb930c80218aefb2e45879a890ede163 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 20.943 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 TAM4_728 bb930c80218aefb2e45879a890ede163 59 SUPERFAMILY SSF144210 4 51 1.31E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TAM4_728 bb930c80218aefb2e45879a890ede163 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 1.4E-27 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TAM4_728 bb930c80218aefb2e45879a890ede163 59 Gene3D G3DSA:2.20.28.40 1 59 1.8E-31 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TAM4_2394 cc1e6e141ec2b286fb31c08889ec5541 288 SMART SM00493 5 84 8.9E-9 T 23-10-2018 IPR006171 TOPRIM domain TAM4_2394 cc1e6e141ec2b286fb31c08889ec5541 288 Gene3D G3DSA:3.40.1360.10 4 120 1.2E-6 T 23-10-2018 TAM4_2394 cc1e6e141ec2b286fb31c08889ec5541 288 Pfam PF01751 Toprim domain 8 88 3.3E-8 T 23-10-2018 IPR006171 TOPRIM domain TAM4_2394 cc1e6e141ec2b286fb31c08889ec5541 288 SUPERFAMILY SSF46579 142 211 2.88E-5 T 23-10-2018 TAM4_2394 cc1e6e141ec2b286fb31c08889ec5541 288 Pfam PF02183 Homeobox associated leucine zipper 151 181 9.3E-7 T 23-10-2018 IPR003106 Leucine zipper, homeobox-associated GO:0003700|GO:0006355|GO:0043565 Reactome: R-HSA-432722|Reactome: R-HSA-6807878 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 SUPERFAMILY SSF54984 7 91 1.31E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 39.586 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 8 91 3.0E-20 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 Gene3D G3DSA:3.30.70.60 1 91 6.6E-35 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 SMART SM00888 5 91 2.8E-27 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 6 90 4.3E-22 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TAM4_1431 949de6672d3bd93ae1e4f73446e87031 91 PIRSF PIRSF006521 3 91 1.4E-31 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 184 340 4.1E-36 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 554 680 5.8E-21 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_973 71121f4e57872e5c453881ff80b9327c 713 SUPERFAMILY SSF55326 376 534 6.15E-51 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Gene3D G3DSA:3.30.1330.10 27 175 1.4E-121 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 703 1.3E-291 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 260.184 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_973 71121f4e57872e5c453881ff80b9327c 713 SUPERFAMILY SSF56042 543 704 1.48E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Gene3D G3DSA:3.30.1330.10 364 536 1.3E-55 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 2.6E-24 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 8.8E-21 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Gene3D G3DSA:3.90.650.10 541 709 7.0E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 Gene3D G3DSA:3.90.650.10 12 340 1.4E-121 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 PIRSF PIRSF001587 1 712 3.6E-280 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_973 71121f4e57872e5c453881ff80b9327c 713 SUPERFAMILY SSF56042 183 402 1.21E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_973 71121f4e57872e5c453881ff80b9327c 713 SUPERFAMILY SSF55326 19 178 8.37E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 2.2E-108 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 SMART SM00663 211 515 2.7E-204 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 8.8E-38 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 3.6E-73 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:2.20.25.410 850 900 2.3E-21 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:3.30.1490.180 354 418 5.8E-80 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:1.20.120.1280 1 121 1.7E-31 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:1.10.132.30 672 813 1.6E-44 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 6.5E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:1.10.274.100 491 671 1.6E-65 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 SUPERFAMILY SSF64484 4 886 0.0 T 23-10-2018 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 698 804 1.0E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TAM4_1637 3b0cd51493c8ac80e1c5e9411ad305fc 905 Gene3D G3DSA:2.40.40.20 311 482 5.8E-80 T 23-10-2018 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 Gene3D G3DSA:3.30.930.10 108 455 2.7E-137 T 23-10-2018 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 SUPERFAMILY SSF46589 1 115 1.67E-27 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 Gene3D G3DSA:1.10.287.40 1 107 1.6E-34 T 23-10-2018 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PIRSF PIRSF001529 1 447 2.0E-155 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.8E-27 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 1.2E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 SUPERFAMILY SSF55681 155 446 4.98E-90 T 23-10-2018 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 42.004 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_20 9e8dfffba9d5168d1eab112693bae2ec 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 1.1E-162 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TAM4_2151 94d58e3e20c615f1c615830419685557 451 Gene3D G3DSA:3.90.550.10 84 300 1.5E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_2151 94d58e3e20c615f1c615830419685557 451 SUPERFAMILY SSF53448 85 349 1.1E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_2151 94d58e3e20c615f1c615830419685557 451 Pfam PF00535 Glycosyl transferase family 2 92 207 4.9E-31 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_812 275c15780d215dafc6e93d1553e43397 257 Pfam PF01261 Xylose isomerase-like TIM barrel 26 220 9.8E-33 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TAM4_812 275c15780d215dafc6e93d1553e43397 257 Gene3D G3DSA:3.20.20.150 1 257 1.3E-62 T 23-10-2018 TAM4_812 275c15780d215dafc6e93d1553e43397 257 SUPERFAMILY SSF51658 11 254 3.14E-51 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TAM4_200 ea8d2945ee7e01db73dcc0cecc2377d0 279 SUPERFAMILY SSF53613 2 253 2.34E-33 T 23-10-2018 IPR029056 Ribokinase-like TAM4_200 ea8d2945ee7e01db73dcc0cecc2377d0 279 Pfam PF00294 pfkB family carbohydrate kinase 179 252 3.9E-5 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TAM4_200 ea8d2945ee7e01db73dcc0cecc2377d0 279 Gene3D G3DSA:3.40.1190.20 1 274 1.3E-89 T 23-10-2018 IPR029056 Ribokinase-like TAM4_992 e97160c1a97f69d47f1c89d9bd6711b1 257 Gene3D G3DSA:3.40.50.300 1 224 8.3E-46 T 23-10-2018 TAM4_992 e97160c1a97f69d47f1c89d9bd6711b1 257 SMART SM00382 26 222 2.2E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_992 e97160c1a97f69d47f1c89d9bd6711b1 257 SUPERFAMILY SSF52540 2 209 4.51E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_992 e97160c1a97f69d47f1c89d9bd6711b1 257 Pfam PF00005 ABC transporter 18 151 5.4E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 SUPERFAMILY SSF46785 286 360 1.44E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 Pfam PF01637 ATPase domain predominantly from Archaea 15 247 3.3E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 Gene3D G3DSA:3.40.50.300 1 204 2.8E-42 T 23-10-2018 TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 SUPERFAMILY SSF52540 2 276 3.73E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 Gene3D G3DSA:1.10.8.60 206 283 1.3E-23 T 23-10-2018 TAM4_197 bb4271bd0c7513c5210e8668a4d1c90b 362 Gene3D G3DSA:1.10.10.10 288 361 3.9E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1842 f5ada89937e303442c2a5e33372d10b3 327 Gene3D G3DSA:3.10.310.40 221 321 1.8E-6 T 23-10-2018 TAM4_1842 f5ada89937e303442c2a5e33372d10b3 327 Gene3D G3DSA:3.90.1640.10 6 188 2.5E-38 T 23-10-2018 TAM4_1842 f5ada89937e303442c2a5e33372d10b3 327 Pfam PF01368 DHH family 21 159 1.9E-12 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TAM4_1842 f5ada89937e303442c2a5e33372d10b3 327 SUPERFAMILY SSF64182 18 306 3.4E-50 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TAM4_1842 f5ada89937e303442c2a5e33372d10b3 327 Pfam PF02272 DHHA1 domain 239 318 4.8E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TAM4_2104 d868c61024fa333d8de5c486ae211276 131 Pfam PF01850 PIN domain 3 111 6.5E-12 T 23-10-2018 IPR002716 PIN domain TAM4_2104 d868c61024fa333d8de5c486ae211276 131 SUPERFAMILY SSF88723 1 116 3.08E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2104 d868c61024fa333d8de5c486ae211276 131 Gene3D G3DSA:3.40.50.1010 1 122 7.2E-15 T 23-10-2018 TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 PIRSF PIRSF004884 1 309 9.5E-103 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 Gene3D G3DSA:3.30.230.10 16 141 7.9E-12 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 307 3.1E-50 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 SUPERFAMILY SSF54211 1 147 3.79E-20 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 Pfam PF08544 GHMP kinases C terminal 203 284 3.0E-5 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TAM4_1771 04b362d65228f46d4a3d19748f0dc944 322 Pfam PF00288 GHMP kinases N terminal domain 76 136 7.4E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TAM4_212 170c821a043a60471e6e32286453da7a 192 Pfam PF09851 Short C-terminal domain 162 189 2.9E-11 T 23-10-2018 IPR018649 SHOCT domain TAM4_212 170c821a043a60471e6e32286453da7a 192 Pfam PF14470 Bacterial PH domain 17 109 8.9E-21 T 23-10-2018 IPR039519 YokE-like, PH domain TAM4_2103 4dc21be4fcbc7417726b6e26665e1c4d 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 4.6E-126 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TAM4_2103 4dc21be4fcbc7417726b6e26665e1c4d 324 SMART SM00729 17 247 6.7E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_2103 4dc21be4fcbc7417726b6e26665e1c4d 324 Pfam PF04055 Radical SAM superfamily 35 180 3.1E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_2103 4dc21be4fcbc7417726b6e26665e1c4d 324 SUPERFAMILY SSF102114 16 255 9.94E-16 T 23-10-2018 TAM4_2103 4dc21be4fcbc7417726b6e26665e1c4d 324 PIRSF PIRSF004954 1 318 5.9E-101 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 PIRSF PIRSF000429 1 383 9.0E-67 T 23-10-2018 IPR002155 Thiolase GO:0016747 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 SUPERFAMILY SSF53901 4 229 1.43E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 SUPERFAMILY SSF53901 233 384 9.29E-29 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 6.0E-27 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 Gene3D G3DSA:3.40.47.10 4 385 3.6E-124 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TAM4_466 d2be7c1322b43becc0fad7b8d14fff05 386 Pfam PF02803 Thiolase, C-terminal domain 244 355 1.2E-10 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TAM4_2134 3cb435a673427a10ae5d91bbdd784578 141 Gene3D G3DSA:1.10.287.370 8 139 4.4E-34 T 23-10-2018 IPR009053 Prefoldin TAM4_2134 3cb435a673427a10ae5d91bbdd784578 141 SUPERFAMILY SSF46579 9 139 2.56E-24 T 23-10-2018 TAM4_2134 3cb435a673427a10ae5d91bbdd784578 141 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 139 14.663 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_2134 3cb435a673427a10ae5d91bbdd784578 141 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 10 138 7.4E-25 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_2134 3cb435a673427a10ae5d91bbdd784578 141 Pfam PF02996 Prefoldin subunit 22 137 1.2E-21 T 23-10-2018 IPR004127 Prefoldin alpha-like TAM4_1284 81431ff5eb2e90441086391033da0581 136 SUPERFAMILY SSF88723 5 122 3.08E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1284 81431ff5eb2e90441086391033da0581 136 Gene3D G3DSA:3.40.50.1010 3 134 1.3E-13 T 23-10-2018 TAM4_1284 81431ff5eb2e90441086391033da0581 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 130 9.776 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_1284 81431ff5eb2e90441086391033da0581 136 SMART SM00670 3 121 9.1E-4 T 23-10-2018 IPR002716 PIN domain TAM4_1284 81431ff5eb2e90441086391033da0581 136 Pfam PF01850 PIN domain 6 124 1.1E-15 T 23-10-2018 IPR002716 PIN domain TAM4_384 221fb9e070442ebb24fd5e1d9a85d6b2 189 Pfam PF00156 Phosphoribosyl transferase domain 40 159 6.4E-19 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_384 221fb9e070442ebb24fd5e1d9a85d6b2 189 Gene3D G3DSA:3.40.50.2020 1 188 2.9E-58 T 23-10-2018 TAM4_384 221fb9e070442ebb24fd5e1d9a85d6b2 189 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 189 27.655 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_384 221fb9e070442ebb24fd5e1d9a85d6b2 189 SUPERFAMILY SSF53271 2 179 5.64E-45 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_384 221fb9e070442ebb24fd5e1d9a85d6b2 189 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 175 1.7E-52 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 Gene3D G3DSA:3.40.50.1260 12 400 1.1E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 Pfam PF00162 Phosphoglycerate kinase 8 392 7.8E-108 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 Gene3D G3DSA:3.40.50.1260 192 393 1.1E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 SUPERFAMILY SSF53748 4 403 1.41E-117 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PIRSF PIRSF000724 1 409 1.2E-130 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 357 368 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 324 349 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 108 123 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 173 195 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 PRINTS PR00477 Phosphoglycerate kinase family signature 196 215 3.7E-68 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1988 5508de7b92808b8ec8fce1288d4dfdf5 410 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 403 35.168 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_2363 a4cd010c30e3db2e68949958c98d35dd 298 Gene3D G3DSA:1.10.357.140 20 173 2.9E-46 T 23-10-2018 TAM4_2363 a4cd010c30e3db2e68949958c98d35dd 298 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 14 294 1.2E-77 T 23-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related TAM4_2363 a4cd010c30e3db2e68949958c98d35dd 298 Pfam PF01040 UbiA prenyltransferase family 30 270 2.1E-36 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TAM4_2363 a4cd010c30e3db2e68949958c98d35dd 298 Gene3D G3DSA:1.20.120.1780 174 296 4.7E-35 T 23-10-2018 TAM4_574 9b29b5d4570c7ed90f8ce320d0468802 446 SUPERFAMILY SSF101960 16 442 2.48E-101 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TAM4_574 9b29b5d4570c7ed90f8ce320d0468802 446 Pfam PF01458 Uncharacterized protein family (UPF0051) 195 418 7.3E-52 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TAM4_205 11d984284745e32898f9bc76701fb784 166 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 2.7E-35 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TAM4_205 11d984284745e32898f9bc76701fb784 166 SUPERFAMILY SSF55729 17 158 1.13E-38 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_205 11d984284745e32898f9bc76701fb784 166 Gene3D G3DSA:3.40.630.30 12 162 1.1E-48 T 23-10-2018 TAM4_205 11d984284745e32898f9bc76701fb784 166 Pfam PF00583 Acetyltransferase (GNAT) family 29 137 6.7E-28 T 23-10-2018 IPR000182 GNAT domain TAM4_2442 0c074fa69e26d166992d894087225ccd 95 SUPERFAMILY SSF111057 6 79 6.41E-22 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TAM4_2442 0c074fa69e26d166992d894087225ccd 95 Pfam PF08967 Domain of unknown function (DUF1884) 6 81 2.3E-20 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_2442 0c074fa69e26d166992d894087225ccd 95 PIRSF PIRSF004604 3 94 9.7E-27 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_2442 0c074fa69e26d166992d894087225ccd 95 Gene3D G3DSA:3.30.2320.10 3 80 3.0E-19 T 23-10-2018 TAM4_2442 0c074fa69e26d166992d894087225ccd 95 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 7 78 2.0E-17 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TAM4_106 3c991c8c8a6cddd96640b2464f5ed69d 150 Hamap MF_02115 FAD synthase [ribL]. 9 149 30.521 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TAM4_106 3c991c8c8a6cddd96640b2464f5ed69d 150 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 76 6.7E-22 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_106 3c991c8c8a6cddd96640b2464f5ed69d 150 Pfam PF01467 Cytidylyltransferase-like 12 143 6.2E-25 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TAM4_106 3c991c8c8a6cddd96640b2464f5ed69d 150 Gene3D G3DSA:3.40.50.620 2 148 2.5E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_106 3c991c8c8a6cddd96640b2464f5ed69d 150 SUPERFAMILY SSF52374 10 144 4.44E-28 T 23-10-2018 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 Gene3D G3DSA:3.30.300.10 30 154 1.3E-170 T 23-10-2018 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 Gene3D G3DSA:3.30.300.280 16 398 1.3E-170 T 23-10-2018 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 1.1E-178 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 51.79 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 Gene3D G3DSA:3.30.300.340 18 286 1.3E-170 T 23-10-2018 TAM4_2471 a30a53e14e07d8df7e709ef74a195b80 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.1E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 5.3E-75 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 Gene3D G3DSA:3.40.50.970 11 211 1.1E-75 T 23-10-2018 TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 SUPERFAMILY SSF52518 23 278 1.62E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 SUPERFAMILY SSF52922 286 393 1.26E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_1882 a3dad4aa0db728cd44bb755cb7191ebd 396 Gene3D G3DSA:3.40.50.920 283 395 1.4E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 SUPERFAMILY SSF56112 2 260 1.91E-65 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 Gene3D G3DSA:1.10.510.10 92 314 3.4E-45 T 23-10-2018 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 Pfam PF00069 Protein kinase domain 4 252 3.3E-46 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 10 33 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 SMART SM00220 4 265 2.6E-45 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_2327 5feca1d4653622a1a5a39850b4673be6 385 Gene3D G3DSA:3.30.200.20 1 79 1.4E-17 T 23-10-2018 TAM4_145 1166590c2ad5bded9f3f11627f8a8e3c 118 Gene3D G3DSA:3.40.1230.10 1 118 1.4E-36 T 23-10-2018 IPR036748 MTH938-like superfamily TAM4_145 1166590c2ad5bded9f3f11627f8a8e3c 118 SUPERFAMILY SSF64076 2 118 4.32E-36 T 23-10-2018 IPR036748 MTH938-like superfamily TAM4_145 1166590c2ad5bded9f3f11627f8a8e3c 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 7 114 2.7E-12 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein TAM4_558 eb7fba07243be7cbcf61936c7169a5f5 386 Gene3D G3DSA:1.10.3720.10 121 366 3.8E-29 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_558 eb7fba07243be7cbcf61936c7169a5f5 386 SUPERFAMILY SSF161098 127 345 1.57E-30 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_558 eb7fba07243be7cbcf61936c7169a5f5 386 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 44 98 3.4E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TAM4_558 eb7fba07243be7cbcf61936c7169a5f5 386 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 365 2.3E-33 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_2 2e06ac82acf3ee486e77b5a51e4e11fd 220 SUPERFAMILY SSF48317 54 216 1.31E-5 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TAM4_2 2e06ac82acf3ee486e77b5a51e4e11fd 220 Pfam PF14378 PAP2 superfamily 61 214 4.5E-12 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 TAM4_2 2e06ac82acf3ee486e77b5a51e4e11fd 220 Gene3D G3DSA:1.20.144.10 139 219 3.4E-5 T 23-10-2018 TAM4_372 c466069751cc64e22af9e1e05dfc524b 81 Pfam PF03683 Uncharacterised protein family (UPF0175) 5 77 8.0E-28 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 TAM4_754 961e6b1978562d97097b3859e32c02a0 301 SUPERFAMILY SSF52540 29 269 3.28E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_754 961e6b1978562d97097b3859e32c02a0 301 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 38 269 5.6E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_754 961e6b1978562d97097b3859e32c02a0 301 PIRSF PIRSF005647 36 300 7.7E-63 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type TAM4_754 961e6b1978562d97097b3859e32c02a0 301 Gene3D G3DSA:3.40.50.300 36 298 2.4E-56 T 23-10-2018 TAM4_240 12e3561a1b64d0797c90162cdcf25f74 142 Pfam PF02310 B12 binding domain 8 122 3.4E-23 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TAM4_240 12e3561a1b64d0797c90162cdcf25f74 142 Gene3D G3DSA:3.40.50.280 1 141 1.2E-55 T 23-10-2018 TAM4_240 12e3561a1b64d0797c90162cdcf25f74 142 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 6.6E-58 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TAM4_240 12e3561a1b64d0797c90162cdcf25f74 142 SUPERFAMILY SSF52242 5 132 8.77E-48 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TAM4_1434 79ef99ce0256bc9ab66b2e17c58533b5 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 8 249 1.4E-83 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TAM4_1434 79ef99ce0256bc9ab66b2e17c58533b5 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 52.484 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TAM4_1434 79ef99ce0256bc9ab66b2e17c58533b5 254 Gene3D G3DSA:3.40.50.620 7 254 4.9E-94 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1434 79ef99ce0256bc9ab66b2e17c58533b5 254 SUPERFAMILY SSF52402 3 249 1.94E-79 T 23-10-2018 TAM4_1434 79ef99ce0256bc9ab66b2e17c58533b5 254 Pfam PF02540 NAD synthase 9 249 2.9E-87 T 23-10-2018 IPR022310 NAD/GMP synthase TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 SUPERFAMILY SSF143437 95 182 1.08E-10 T 23-10-2018 TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 Pfam PF02926 THUMP domain 31 182 1.4E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 2.6E-38 T 23-10-2018 IPR000241 Putative RNA methylase domain TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 SMART SM00981 86 182 1.9E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 Gene3D G3DSA:3.30.2130.30 1 189 3.6E-83 T 23-10-2018 TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 Gene3D G3DSA:3.40.50.150 190 365 2.9E-51 T 23-10-2018 TAM4_1322 81190b98f5cad6d58a6b0dce9076179d 365 SUPERFAMILY SSF53335 177 358 1.63E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 443 2.8E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 SUPERFAMILY SSF53738 261 367 3.92E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Gene3D G3DSA:3.30.310.50 371 455 4.4E-32 T 23-10-2018 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 447 4.1E-181 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 2.0E-47 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 SUPERFAMILY SSF55957 358 454 3.66E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 2.5E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Gene3D G3DSA:3.40.120.10 169 358 5.9E-78 T 23-10-2018 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Gene3D G3DSA:3.40.120.10 1 152 6.8E-64 T 23-10-2018 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Gene3D G3DSA:3.40.120.10 257 365 5.9E-78 T 23-10-2018 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 SUPERFAMILY SSF53738 155 259 1.1E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 SUPERFAMILY SSF53738 3 180 2.9E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_546 5410bb63e7810e000c6e27cf0c1e0acd 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 2.4E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 SUPERFAMILY SSF53067 250 487 3.99E-83 T 23-10-2018 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 5.7E-55 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 246 3.6E-88 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 SUPERFAMILY SSF53067 4 247 2.29E-95 T 23-10-2018 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 Hamap MF_00186 Glycerol kinase [glpK]. 2 488 57.057 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 Gene3D G3DSA:3.30.420.40 249 492 2.8E-94 T 23-10-2018 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 PIRSF PIRSF000538 2 491 1.0E-179 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 Gene3D G3DSA:3.30.420.40 1 247 7.4E-115 T 23-10-2018 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 487 4.7E-216 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TAM4_90 e46ce520e0791e93d7620de3a6775df7 493 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TAM4_1866 a8dd56af81736e63ff37df209686b246 581 SMART SM00729 200 447 4.1E-32 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1866 a8dd56af81736e63ff37df209686b246 581 SUPERFAMILY SSF102114 189 451 8.89E-27 T 23-10-2018 TAM4_1866 a8dd56af81736e63ff37df209686b246 581 Gene3D G3DSA:1.10.150.320 518 579 2.9E-5 T 23-10-2018 TAM4_1866 a8dd56af81736e63ff37df209686b246 581 SUPERFAMILY SSF81585 512 579 1.05E-7 T 23-10-2018 TAM4_1866 a8dd56af81736e63ff37df209686b246 581 Gene3D G3DSA:3.80.30.20 200 457 2.5E-25 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TAM4_1866 a8dd56af81736e63ff37df209686b246 581 Pfam PF04055 Radical SAM superfamily 204 403 4.3E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_983 4f224c38063fa9f5b9bfb71e335ec02c 320 Gene3D G3DSA:3.90.1150.10 19 315 1.1E-67 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_983 4f224c38063fa9f5b9bfb71e335ec02c 320 Pfam PF00155 Aminotransferase class I and II 26 314 1.5E-31 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_983 4f224c38063fa9f5b9bfb71e335ec02c 320 Gene3D G3DSA:3.40.640.10 30 233 1.1E-67 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_983 4f224c38063fa9f5b9bfb71e335ec02c 320 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TAM4_983 4f224c38063fa9f5b9bfb71e335ec02c 320 SUPERFAMILY SSF53383 13 317 9.21E-54 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 Gene3D G3DSA:1.20.1090.10 156 345 8.4E-67 T 23-10-2018 TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 Gene3D G3DSA:3.40.50.1970 1 155 6.1E-35 T 23-10-2018 TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 346 46.85 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 PIRSF PIRSF000112 2 343 4.2E-67 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 SUPERFAMILY SSF56796 3 339 2.88E-73 T 23-10-2018 TAM4_1506 1ea8c7281345f55d4ebcab410077a9a5 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 268 5.1E-73 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TAM4_258 06355edf318d4861d0b067557e32cd11 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 99 7.9E-9 T 23-10-2018 IPR006675 HDIG domain TAM4_258 06355edf318d4861d0b067557e32cd11 206 Gene3D G3DSA:1.10.3210.50 13 206 2.1E-63 T 23-10-2018 TAM4_258 06355edf318d4861d0b067557e32cd11 206 SUPERFAMILY SSF109604 14 205 1.54E-61 T 23-10-2018 TAM4_258 06355edf318d4861d0b067557e32cd11 206 SMART SM00471 30 147 1.7E-10 T 23-10-2018 IPR003607 HD/PDEase domain TAM4_258 06355edf318d4861d0b067557e32cd11 206 Pfam PF01966 HD domain 35 137 8.3E-19 T 23-10-2018 IPR006674 HD domain TAM4_1073 f76e2d9604a49a58c3f4419659bc54fb 223 Pfam PF13483 Beta-lactamase superfamily domain 3 188 2.4E-32 T 23-10-2018 TAM4_1073 f76e2d9604a49a58c3f4419659bc54fb 223 Gene3D G3DSA:3.60.15.10 2 223 1.3E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1073 f76e2d9604a49a58c3f4419659bc54fb 223 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 223 39.372 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 TAM4_1073 f76e2d9604a49a58c3f4419659bc54fb 223 SMART SM00849 8 188 7.5E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1073 f76e2d9604a49a58c3f4419659bc54fb 223 SUPERFAMILY SSF56281 1 222 6.16E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1481 8299b8d170a05089662e395853f93a92 93 SUPERFAMILY SSF54786 1 65 8.24E-7 T 23-10-2018 TAM4_1481 8299b8d170a05089662e395853f93a92 93 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 62 7.6E-9 T 23-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TAM4_1481 8299b8d170a05089662e395853f93a92 93 Gene3D G3DSA:3.30.920.30 1 65 1.7E-6 T 23-10-2018 IPR038570 HicA superfamily TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 131 1.3E-29 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 PIRSF PIRSF004761 1 137 1.2E-36 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 22.066 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 Gene3D G3DSA:3.30.2320.50 1 73 4.9E-28 T 23-10-2018 TAM4_1300 e2929270e27fccd0bbf70a66f719028d 139 Gene3D G3DSA:2.20.28.10 74 123 2.4E-27 T 23-10-2018 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 Pfam PF01176 Translation initiation factor 1A / IF-1 32 95 1.5E-19 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 41 63 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 16 110 4.7E-35 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 Gene3D G3DSA:2.40.50.140 9 122 7.2E-38 T 23-10-2018 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 15 111 28.101 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 SUPERFAMILY SSF50249 4 114 9.71E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 53 110 1.0E-25 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TAM4_1492 a272c8f5748f9d42f2df3f4eaed6bf7d 122 SMART SM00652 28 111 8.4E-41 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 Pfam PF09336 Vps4 C terminal oligomerisation domain 331 380 1.7E-7 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 SMART SM00382 134 269 1.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 138 267 5.2E-37 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 SUPERFAMILY SSF52540 102 379 5.4E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 Gene3D G3DSA:3.40.50.300 99 376 1.1E-79 T 23-10-2018 TAM4_987 ce799e68d910baace16ee375b1b0cdd9 381 Gene3D G3DSA:1.10.8.60 268 360 1.1E-79 T 23-10-2018 TAM4_565 447ec3c08d912c55c573a8f836a4185d 278 Gene3D G3DSA:3.30.1360.130 118 262 3.9E-77 T 23-10-2018 TAM4_565 447ec3c08d912c55c573a8f836a4185d 278 Gene3D G3DSA:3.40.50.10780 1 216 3.9E-77 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal TAM4_565 447ec3c08d912c55c573a8f836a4185d 278 PIRSF PIRSF015853 1 276 1.8E-97 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TAM4_565 447ec3c08d912c55c573a8f836a4185d 278 SUPERFAMILY SSF63992 1 273 2.88E-85 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily TAM4_565 447ec3c08d912c55c573a8f836a4185d 278 Pfam PF04951 D-aminopeptidase 1 264 1.9E-83 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TAM4_542 9c94eebd3617674207bc0f80bf189ba0 99 SUPERFAMILY SSF50447 1 73 4.24E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_542 9c94eebd3617674207bc0f80bf189ba0 99 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 9.0E-28 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 TAM4_542 9c94eebd3617674207bc0f80bf189ba0 99 Gene3D G3DSA:2.40.10.230 1 75 2.4E-26 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain TAM4_542 9c94eebd3617674207bc0f80bf189ba0 99 Pfam PF04410 Gar1/Naf1 RNA binding region 2 75 1.6E-8 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 Gene3D G3DSA:3.50.20.10 44 156 2.7E-35 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 2.0E-67 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 Gene3D G3DSA:3.30.60.30 1 43 5.7E-18 T 23-10-2018 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 2.2E-41 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 49.593 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 SUPERFAMILY SSF56271 2 155 3.14E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 4.1E-41 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_904 d90892c2f6a6bd14d761d16e88e0c103 157 PIRSF PIRSF005216 2 157 3.6E-48 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TAM4_275 c8f91876c7d937b11561cd01e7624cea 195 Pfam PF00565 Staphylococcal nuclease homologue 73 191 2.3E-22 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TAM4_275 c8f91876c7d937b11561cd01e7624cea 195 SUPERFAMILY SSF50199 47 192 1.7E-30 T 23-10-2018 TAM4_275 c8f91876c7d937b11561cd01e7624cea 195 SMART SM00318 47 193 2.0E-28 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TAM4_275 c8f91876c7d937b11561cd01e7624cea 195 Gene3D G3DSA:2.40.50.90 43 194 8.3E-38 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily TAM4_2121 e202e50946d1b9406dd99dd67388cfd3 321 SUPERFAMILY SSF53850 55 313 2.56E-37 T 23-10-2018 TAM4_2121 e202e50946d1b9406dd99dd67388cfd3 321 Gene3D G3DSA:3.40.190.10 44 128 3.8E-8 T 23-10-2018 TAM4_2121 e202e50946d1b9406dd99dd67388cfd3 321 Pfam PF09084 NMT1/THI5 like 53 257 6.5E-13 T 23-10-2018 IPR015168 SsuA/THI5-like TAM4_2121 e202e50946d1b9406dd99dd67388cfd3 321 Gene3D G3DSA:3.40.190.10 132 319 6.7E-22 T 23-10-2018 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 167 216 1.0E-5 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 SUPERFAMILY SSF51351 4 223 1.05E-46 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 1.6E-63 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 Pfam PF00121 Triosephosphate isomerase 8 113 1.0E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 Gene3D G3DSA:3.20.20.70 1 225 5.1E-95 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.702 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 TAM4_1330 05fe9882486e77a8d078a9fefc9a8c73 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 Pfam PF08423 Rad51 100 352 2.8E-93 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 SMART SM00382 133 322 9.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 SUPERFAMILY SSF47794 35 96 2.35E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 SUPERFAMILY SSF52540 114 351 1.49E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 37 352 82.428 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 Pfam PF14520 Helix-hairpin-helix domain 38 93 3.9E-12 T 23-10-2018 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 Gene3D G3DSA:1.10.150.20 38 101 5.3E-25 T 23-10-2018 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 PIRSF PIRSF005856 27 352 3.0E-137 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 40 352 9.6E-165 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 SMART SM00278 38 57 0.011 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 SMART SM00278 71 90 160.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TAM4_1211 3e2adc7cc67b77f7475e5a190ab4fef0 352 Gene3D G3DSA:3.40.50.300 102 352 1.9E-86 T 23-10-2018 TAM4_26 3c40af9025113ef9af0d3c24c61a8792 185 SUPERFAMILY SSF51182 3 182 5.43E-80 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TAM4_26 3c40af9025113ef9af0d3c24c61a8792 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 178 2.2E-85 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TAM4_26 3c40af9025113ef9af0d3c24c61a8792 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 5.7E-77 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TAM4_26 3c40af9025113ef9af0d3c24c61a8792 185 Gene3D G3DSA:2.60.120.10 3 184 2.5E-77 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TAM4_26 3c40af9025113ef9af0d3c24c61a8792 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 2.0E-87 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TAM4_2444 831b60283b35862fbc2a06f08a5cf30f 90 SUPERFAMILY SSF143011 1 87 2.49E-21 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_2444 831b60283b35862fbc2a06f08a5cf30f 90 Gene3D G3DSA:3.30.2310.20 1 90 5.3E-29 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_2444 831b60283b35862fbc2a06f08a5cf30f 90 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 88 4.8E-6 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TAM4_2126 e9e1ab7b81e335e5e2cc4c5c28ebb3ab 247 SMART SM00331 14 246 5.9E-16 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_2126 e9e1ab7b81e335e5e2cc4c5c28ebb3ab 247 SUPERFAMILY SSF81606 12 244 1.57E-44 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_2126 e9e1ab7b81e335e5e2cc4c5c28ebb3ab 247 Gene3D G3DSA:3.60.40.10 8 246 5.7E-50 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_2126 e9e1ab7b81e335e5e2cc4c5c28ebb3ab 247 SMART SM00332 2 244 6.3E-16 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_2126 e9e1ab7b81e335e5e2cc4c5c28ebb3ab 247 Pfam PF13672 Protein phosphatase 2C 20 212 9.0E-16 T 23-10-2018 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 Pfam PF01750 Hydrogenase maturation protease 30 150 4.8E-14 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 PRINTS PR00446 Hydrogen uptake protein signature 13 25 1.9E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 PRINTS PR00446 Hydrogen uptake protein signature 25 36 1.9E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 PRINTS PR00446 Hydrogen uptake protein signature 67 77 1.9E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 Gene3D G3DSA:3.40.50.1450 9 159 5.2E-41 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 151 1.5E-31 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1208 47826a8c98934cba41e9402bdd3d51a6 162 SUPERFAMILY SSF53163 11 156 8.24E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_1390 5d498589265386bf17513dc23a071875 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 55 73 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TAM4_1390 5d498589265386bf17513dc23a071875 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 229 244 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TAM4_1390 5d498589265386bf17513dc23a071875 446 Gene3D G3DSA:3.10.20.70 17 105 4.5E-23 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TAM4_1390 5d498589265386bf17513dc23a071875 446 SUPERFAMILY SSF54368 22 102 2.75E-19 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TAM4_1390 5d498589265386bf17513dc23a071875 446 Gene3D G3DSA:3.30.590.10 106 445 6.5E-129 T 23-10-2018 TAM4_1390 5d498589265386bf17513dc23a071875 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 22 96 3.8E-21 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TAM4_1390 5d498589265386bf17513dc23a071875 446 SMART SM01230 103 346 1.4E-135 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TAM4_1390 5d498589265386bf17513dc23a071875 446 Pfam PF00120 Glutamine synthetase, catalytic domain 104 442 2.4E-131 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TAM4_1390 5d498589265386bf17513dc23a071875 446 SUPERFAMILY SSF55931 105 444 2.94E-124 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TAM4_1390 5d498589265386bf17513dc23a071875 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 22 444 2.4E-176 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TAM4_770 4d4bcae387687d93b1d2b23f2a8fbd59 432 Pfam PF13635 Domain of unknown function (DUF4143) 248 373 9.3E-12 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_770 4d4bcae387687d93b1d2b23f2a8fbd59 432 SUPERFAMILY SSF52540 34 198 8.97E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_770 4d4bcae387687d93b1d2b23f2a8fbd59 432 Pfam PF13173 AAA domain 33 164 9.6E-34 T 23-10-2018 TAM4_1985 3c0240f4563238de6e0cc84ea32f29f2 329 Gene3D G3DSA:2.40.100.10 172 310 4.1E-47 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TAM4_1985 3c0240f4563238de6e0cc84ea32f29f2 329 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 307 4.3E-103 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TAM4_1985 3c0240f4563238de6e0cc84ea32f29f2 329 SMART SM00797 23 300 6.6E-131 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TAM4_1985 3c0240f4563238de6e0cc84ea32f29f2 329 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 1.2E-81 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TAM4_1985 3c0240f4563238de6e0cc84ea32f29f2 329 SUPERFAMILY SSF50891 173 290 6.83E-12 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TAM4_1596 b97d56f707284c987785fcc7f05f3715 418 Pfam PF13173 AAA domain 35 159 2.4E-32 T 23-10-2018 TAM4_1596 b97d56f707284c987785fcc7f05f3715 418 SUPERFAMILY SSF52540 19 221 3.11E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1596 b97d56f707284c987785fcc7f05f3715 418 Pfam PF13635 Domain of unknown function (DUF4143) 218 362 1.1E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 SMART SM00220 139 389 6.3E-58 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 SUPERFAMILY SSF56112 136 383 7.55E-67 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 250 262 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 Pfam PF00069 Protein kinase domain 139 376 8.0E-47 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 Gene3D G3DSA:1.10.510.10 132 407 7.9E-63 T 23-10-2018 TAM4_1638 658dc3578a3c525c7c071fefab140eac 485 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 145 168 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_1674 f98f8fee50d95fa6eac8bd9924451182 67 Gene3D G3DSA:1.10.20.10 1 66 2.1E-25 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_1674 f98f8fee50d95fa6eac8bd9924451182 67 SUPERFAMILY SSF47113 3 66 8.39E-21 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_1674 f98f8fee50d95fa6eac8bd9924451182 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 3.7E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Gene3D G3DSA:3.90.600.20 156 251 2.1E-35 T 23-10-2018 TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Pfam PF01336 OB-fold nucleic acid binding domain 270 342 5.3E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Gene3D G3DSA:3.30.70.2200 1 155 1.1E-61 T 23-10-2018 TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 4.5E-39 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Gene3D G3DSA:2.40.50.1010 252 401 7.9E-44 T 23-10-2018 TAM4_479 cf0126eb74c9487101c7d616c068be52 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 37.615 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 TAM4_2153 7350c411d2de58048e8641fa9b1cfcc7 311 Pfam PF01384 Phosphate transporter family 15 297 1.4E-50 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TAM4_1220 589bddda5f56c2344882ec655060f8f5 198 SUPERFAMILY SSF111278 7 190 2.09E-60 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_1220 589bddda5f56c2344882ec655060f8f5 198 Pfam PF02676 Methyltransferase TYW3 11 191 3.7E-45 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_1220 589bddda5f56c2344882ec655060f8f5 198 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.386 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TAM4_1220 589bddda5f56c2344882ec655060f8f5 198 Gene3D G3DSA:3.30.1960.10 2 196 2.5E-67 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_308 92785339e200b4870c8e77b284a2a731 287 Gene3D G3DSA:3.40.50.720 3 271 6.5E-94 T 23-10-2018 TAM4_308 92785339e200b4870c8e77b284a2a731 287 Pfam PF04321 RmlD substrate binding domain 1 284 1.2E-85 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TAM4_308 92785339e200b4870c8e77b284a2a731 287 Gene3D G3DSA:3.90.25.10 164 277 6.5E-94 T 23-10-2018 TAM4_308 92785339e200b4870c8e77b284a2a731 287 SUPERFAMILY SSF51735 1 283 6.41E-86 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_308 92785339e200b4870c8e77b284a2a731 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 283 5.0E-108 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TAM4_308 92785339e200b4870c8e77b284a2a731 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 112 140 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TAM4_2053 4c6e77124fe739643527ca0e06298b8a 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 87 4.3E-8 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TAM4_2053 4c6e77124fe739643527ca0e06298b8a 87 SUPERFAMILY SSF143011 6 86 5.62E-19 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_2053 4c6e77124fe739643527ca0e06298b8a 87 Gene3D G3DSA:3.30.2310.20 1 87 6.5E-20 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Gene3D G3DSA:3.30.2070.10 407 487 1.9E-123 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 SUPERFAMILY SSF53706 3 525 7.46E-139 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Gene3D G3DSA:3.40.50.740 67 450 1.9E-123 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Gene3D G3DSA:2.20.25.90 2 58 4.3E-10 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Gene3D G3DSA:2.40.40.20 517 639 7.5E-29 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Pfam PF00384 Molybdopterin oxidoreductase 56 414 8.3E-48 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 7.3E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Pfam PF01568 Molydopterin dinucleotide binding domain 525 629 4.5E-20 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 SMART SM00926 1 53 1.1E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 Gene3D G3DSA:3.40.228.10 133 504 1.9E-123 T 23-10-2018 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TAM4_2199 8c1316a32b59845bd06ff81936c9de35 639 SUPERFAMILY SSF50692 516 637 3.52E-33 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 SUPERFAMILY SSF55261 278 404 2.78E-47 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Pfam PF02637 GatB domain 485 624 2.4E-29 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 626 1.7E-240 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Gene3D G3DSA:1.10.150.380 453 546 3.7E-25 T 23-10-2018 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Gene3D G3DSA:1.10.10.410 566 624 4.4E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 SMART SM00845 484 624 8.8E-39 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Gene3D G3DSA:3.30.1360.30 274 404 5.7E-54 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Pfam PF02938 GAD domain 299 390 3.7E-17 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 5.0E-58 T 23-10-2018 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 SUPERFAMILY SSF89095 482 624 1.57E-28 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 628 343.132 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 SUPERFAMILY SSF55931 3 453 3.01E-99 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TAM4_791 afbc74792029ebf131b5d3a66fc877e0 628 Pfam PF02934 GatB/GatE catalytic domain 13 442 1.1E-64 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TAM4_1911 0d785d17f43ca2df8d86deedf6cfadad 183 SUPERFAMILY SSF53323 1 181 1.7E-43 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_1911 0d785d17f43ca2df8d86deedf6cfadad 183 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 4 179 1.8E-26 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TAM4_1911 0d785d17f43ca2df8d86deedf6cfadad 183 Gene3D G3DSA:3.40.920.10 1 183 1.7E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_1911 0d785d17f43ca2df8d86deedf6cfadad 183 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.6E-36 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 SUPERFAMILY SSF54373 223 318 9.55E-8 T 23-10-2018 TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 Gene3D G3DSA:3.30.9.10 90 321 2.9E-116 T 23-10-2018 TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 SUPERFAMILY SSF51905 3 410 1.55E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 Gene3D G3DSA:1.10.10.1100 393 472 9.3E-18 T 23-10-2018 TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 Gene3D G3DSA:3.50.50.60 5 354 2.9E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 Pfam PF01266 FAD dependent oxidoreductase 4 360 1.5E-69 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TAM4_83 98ef020c1a00ec9bee787bb8d45603e2 495 Pfam PF04324 BFD-like [2Fe-2S] binding domain 406 463 9.5E-16 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 60.813 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 Gene3D G3DSA:3.30.230.70 23 248 1.7E-77 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 8.6E-17 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 SUPERFAMILY SSF54211 9 179 3.69E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 SUPERFAMILY SSF55666 153 239 5.76E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 Pfam PF01138 3' exoribonuclease family, domain 1 24 153 1.1E-34 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TAM4_251 0f2812f9ed7246db4bb0849f766d3b3a 248 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 8 237 2.0E-119 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 Gene3D G3DSA:3.40.50.300 18 223 4.9E-69 T 23-10-2018 TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 21 215 5.4E-59 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 Pfam PF02223 Thymidylate kinase 26 215 9.0E-55 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 ProSitePatterns PS01331 Thymidylate kinase signature. 117 129 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 SUPERFAMILY SSF52540 21 221 1.93E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1803 43eafafecac96d9aa14ff390db392a13 227 Hamap MF_00165 Thymidylate kinase [tmk]. 22 223 28.361 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TAM4_1960 7a57c92d5b918a48410604ebd4bf3f82 499 SUPERFAMILY SSF50998 41 346 3.14E-10 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_1960 7a57c92d5b918a48410604ebd4bf3f82 499 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 478 497 3.2E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1385 46614de9683fcdc64618ef6aed8b4dc2 184 SUPERFAMILY SSF52972 1 182 8.9E-63 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TAM4_1385 46614de9683fcdc64618ef6aed8b4dc2 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 2.7E-63 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TAM4_1385 46614de9683fcdc64618ef6aed8b4dc2 184 Gene3D G3DSA:3.90.950.10 1 184 2.4E-72 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TAM4_1385 46614de9683fcdc64618ef6aed8b4dc2 184 Pfam PF01725 Ham1 family 3 178 3.5E-51 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TAM4_1385 46614de9683fcdc64618ef6aed8b4dc2 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 42.196 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TAM4_1699 64182baa5dc7c5f2944b9873dd061c3d 133 Pfam PF01751 Toprim domain 51 86 2.1E-6 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1699 64182baa5dc7c5f2944b9873dd061c3d 133 Hamap MF_01095 UPF0292 protein . 3 123 32.937 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 TAM4_1699 64182baa5dc7c5f2944b9873dd061c3d 133 SUPERFAMILY SSF110455 19 90 4.97E-6 T 23-10-2018 TAM4_1699 64182baa5dc7c5f2944b9873dd061c3d 133 Gene3D G3DSA:3.40.1360.10 2 116 6.6E-22 T 23-10-2018 TAM4_1699 64182baa5dc7c5f2944b9873dd061c3d 133 SMART SM00493 20 90 7.1E-5 T 23-10-2018 IPR006171 TOPRIM domain TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 Gene3D G3DSA:3.40.50.620 1 134 2.8E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 Gene3D G3DSA:3.90.1490.10 137 224 4.8E-32 T 23-10-2018 TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 221 7.8E-92 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 Pfam PF01902 Diphthamide synthase 1 220 1.4E-85 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 PIRSF PIRSF039123 1 224 3.4E-80 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 217 1.5E-88 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 SUPERFAMILY SSF52402 1 220 2.28E-75 T 23-10-2018 TAM4_39 88f791c9fed6e2adc48caa21f7477633 224 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 221 8.3E-84 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 5.7E-73 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 4.8E-40 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 SUPERFAMILY SSF52283 1 131 9.45E-40 T 23-10-2018 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 SUPERFAMILY SSF51735 99 281 1.63E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 Gene3D G3DSA:3.40.50.720 7 298 9.4E-136 T 23-10-2018 TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TAM4_1348 99c55f8c7c54739a3cea78ec2b811d9b 304 Gene3D G3DSA:3.40.50.720 92 282 9.4E-136 T 23-10-2018 TAM4_1781 b5cd7b11e5ab945009cd6fb7dd7d0866 425 SUPERFAMILY SSF103473 40 418 1.28E-48 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1781 b5cd7b11e5ab945009cd6fb7dd7d0866 425 Pfam PF07690 Major Facilitator Superfamily 41 386 7.6E-30 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1781 b5cd7b11e5ab945009cd6fb7dd7d0866 425 Gene3D G3DSA:1.20.1250.20 31 418 1.3E-45 T 23-10-2018 TAM4_559 8953667712b380b20691fb18e76826b3 137 Gene3D G3DSA:3.40.50.1010 2 135 1.9E-19 T 23-10-2018 TAM4_559 8953667712b380b20691fb18e76826b3 137 SUPERFAMILY SSF88723 1 136 1.8E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_559 8953667712b380b20691fb18e76826b3 137 SMART SM00670 1 130 1.6E-5 T 23-10-2018 IPR002716 PIN domain TAM4_559 8953667712b380b20691fb18e76826b3 137 Pfam PF01850 PIN domain 3 130 8.5E-19 T 23-10-2018 IPR002716 PIN domain TAM4_1910 fa0fffec12c089a346ebbde5e982e694 165 Pfam PF01936 NYN domain 22 153 2.8E-20 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TAM4_1910 fa0fffec12c089a346ebbde5e982e694 165 Gene3D G3DSA:3.40.50.1010 13 155 4.6E-12 T 23-10-2018 TAM4_1910 fa0fffec12c089a346ebbde5e982e694 165 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 13 155 2.6E-61 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TAM4_1910 fa0fffec12c089a346ebbde5e982e694 165 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 23 95 3.0E-31 T 23-10-2018 TAM4_462 b31e2e868a0fb208fda2abe3171c67b4 261 SUPERFAMILY SSF102588 27 250 1.28E-56 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TAM4_462 b31e2e868a0fb208fda2abe3171c67b4 261 Pfam PF02585 GlcNAc-PI de-N-acetylase 29 155 1.2E-29 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TAM4_462 b31e2e868a0fb208fda2abe3171c67b4 261 Gene3D G3DSA:3.40.50.10320 2 261 5.5E-97 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.925 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 Gene3D G3DSA:3.20.20.70 12 289 5.3E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 SUPERFAMILY SSF51395 1 298 9.33E-85 T 23-10-2018 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 PIRSF PIRSF000164 1 300 1.1E-87 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 8.0E-66 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 7.6E-131 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TAM4_1200 e073d272ef461847c93d8ebd5571200e 300 Gene3D G3DSA:2.30.26.10 55 212 5.3E-93 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 TAM4_1709 cc89bf9e8d321de78cc69a35c63ab929 452 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 335 436 7.0E-51 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TAM4_1709 cc89bf9e8d321de78cc69a35c63ab929 452 PIRSF PIRSF017066 1 452 4.3E-128 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal TAM4_1709 cc89bf9e8d321de78cc69a35c63ab929 452 Pfam PF04659 Archaeal flagella protein 332 424 6.7E-30 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TAM4_1028 36f068e1cf2012e52b754b8cebf79a3c 115 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 2.6E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_1028 36f068e1cf2012e52b754b8cebf79a3c 115 Pfam PF03334 Na+/H+ antiporter subunit 11 96 1.3E-15 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_1728 7668eca814d94839ef191614c90bdad6 460 Gene3D G3DSA:3.30.1110.20 19 199 3.6E-156 T 23-10-2018 TAM4_1728 7668eca814d94839ef191614c90bdad6 460 SUPERFAMILY SSF53613 11 456 8.99E-155 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1728 7668eca814d94839ef191614c90bdad6 460 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 12 448 5.9E-111 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TAM4_1728 7668eca814d94839ef191614c90bdad6 460 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 12 457 2.0E-234 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TAM4_1728 7668eca814d94839ef191614c90bdad6 460 Gene3D G3DSA:3.40.1190.20 13 447 3.6E-156 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1728 7668eca814d94839ef191614c90bdad6 460 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 5 457 44.071 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TAM4_1728 7668eca814d94839ef191614c90bdad6 460 PIRSF PIRSF015883 1 457 5.6E-201 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TAM4_163 e7429e026e195b55d1e0dddc7ce6e96a 111 Pfam PF01934 Protein of unknown function DUF86 11 106 1.0E-32 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 SMART SM00997 147 299 0.0093 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 Gene3D G3DSA:3.40.50.720 98 290 1.5E-142 T 23-10-2018 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 SUPERFAMILY SSF52283 2 133 2.65E-43 T 23-10-2018 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 1.1E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 2.0E-67 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 60.492 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 Gene3D G3DSA:3.40.50.720 4 317 1.5E-142 T 23-10-2018 TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TAM4_137 c422cf2e4b18ce903b1dea361e51708b 334 SUPERFAMILY SSF51735 103 290 1.23E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1123 4311d0e675f832ad4810dab297543817 253 SMART SM00062 32 253 4.4E-77 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TAM4_1123 4311d0e675f832ad4810dab297543817 253 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 56 69 - T 23-10-2018 IPR018313 Solute-binding protein family 3, conserved site TAM4_1123 4311d0e675f832ad4810dab297543817 253 Gene3D G3DSA:3.40.190.10 31 246 5.7E-74 T 23-10-2018 TAM4_1123 4311d0e675f832ad4810dab297543817 253 SMART SM00079 32 253 1.2E-5 T 23-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TAM4_1123 4311d0e675f832ad4810dab297543817 253 SUPERFAMILY SSF53850 5 252 3.49E-75 T 23-10-2018 TAM4_1123 4311d0e675f832ad4810dab297543817 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 252 7.2E-74 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TAM4_1123 4311d0e675f832ad4810dab297543817 253 Gene3D G3DSA:3.40.190.10 122 212 5.7E-74 T 23-10-2018 TAM4_580 73f0536c1617bde690c16f0f412092ee 67 SUPERFAMILY SSF54285 4 67 1.74E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TAM4_580 73f0536c1617bde690c16f0f412092ee 67 Gene3D G3DSA:3.10.20.30 1 67 1.1E-24 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TAM4_580 73f0536c1617bde690c16f0f412092ee 67 Pfam PF02597 ThiS family 10 67 2.2E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TAM4_1057 b50b5d41465fb769e837de3956242541 375 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 295 353 2.5E-9 T 23-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TAM4_1057 b50b5d41465fb769e837de3956242541 375 Gene3D G3DSA:3.20.20.70 3 261 2.0E-7 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1057 b50b5d41465fb769e837de3956242541 375 Gene3D G3DSA:1.10.10.10 267 373 7.7E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1057 b50b5d41465fb769e837de3956242541 375 SUPERFAMILY SSF102114 5 263 3.14E-9 T 23-10-2018 TAM4_1057 b50b5d41465fb769e837de3956242541 375 SUPERFAMILY SSF46785 277 367 3.38E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1580 195710f7b9b8328a98bfe617370189ea 127 Gene3D G3DSA:1.20.120.330 2 125 7.6E-37 T 23-10-2018 TAM4_1580 195710f7b9b8328a98bfe617370189ea 127 SUPERFAMILY SSF81593 8 123 4.71E-6 T 23-10-2018 TAM4_1580 195710f7b9b8328a98bfe617370189ea 127 Pfam PF05168 HEPN domain 5 121 3.7E-25 T 23-10-2018 IPR007842 HEPN domain TAM4_742 02efc4681e9207fe56100f6357de21f9 157 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 7 152 1.5E-46 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TAM4_742 02efc4681e9207fe56100f6357de21f9 157 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.897 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TAM4_742 02efc4681e9207fe56100f6357de21f9 157 Pfam PF00692 dUTPase 43 139 4.8E-14 T 23-10-2018 IPR029054 dUTPase-like TAM4_742 02efc4681e9207fe56100f6357de21f9 157 Gene3D G3DSA:2.70.40.10 1 156 1.5E-42 T 23-10-2018 IPR036157 dUTPase-like superfamily TAM4_742 02efc4681e9207fe56100f6357de21f9 157 SUPERFAMILY SSF51283 1 152 1.24E-39 T 23-10-2018 IPR036157 dUTPase-like superfamily TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 Gene3D G3DSA:3.30.70.100 166 260 1.9E-33 T 23-10-2018 TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 Pfam PF00924 Mechanosensitive ion channel 59 255 3.8E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 SUPERFAMILY SSF50182 100 166 2.94E-15 T 23-10-2018 IPR010920 LSM domain superfamily TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 SUPERFAMILY SSF82861 15 99 2.09E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 Gene3D G3DSA:2.30.30.60 116 165 3.1E-15 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TAM4_2062 49c43b2c4bc0269dcd5ed09e38cce0a8 269 SUPERFAMILY SSF82689 167 265 1.06E-35 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 SUPERFAMILY SSF52374 2 363 1.83E-66 T 23-10-2018 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 PIRSF PIRSF006588 1 375 1.6E-130 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 Gene3D G3DSA:1.10.240.10 227 375 1.3E-56 T 23-10-2018 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 Pfam PF00579 tRNA synthetases class I (W and Y) 34 352 5.7E-44 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.826 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TAM4_2345 5766ceaf82918edaa36c3c94cf28ff2c 375 Gene3D G3DSA:3.40.50.620 1 226 1.3E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_357 618bb788df28e14a72dbf31e0840449a 384 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 9 380 1.3E-166 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TAM4_357 618bb788df28e14a72dbf31e0840449a 384 SUPERFAMILY SSF53383 2 383 2.1E-105 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_357 618bb788df28e14a72dbf31e0840449a 384 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.305 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TAM4_357 618bb788df28e14a72dbf31e0840449a 384 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 TAM4_357 618bb788df28e14a72dbf31e0840449a 384 Gene3D G3DSA:3.90.1150.10 5 374 3.2E-124 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_357 618bb788df28e14a72dbf31e0840449a 384 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 67 331 3.3E-33 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TAM4_357 618bb788df28e14a72dbf31e0840449a 384 Gene3D G3DSA:3.40.640.10 40 290 3.2E-124 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 Gene3D G3DSA:1.10.287.70 2 105 5.2E-22 T 23-10-2018 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 PRINTS PR00169 Potassium channel signature 62 88 1.3E-8 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 PRINTS PR00169 Potassium channel signature 33 55 1.3E-8 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 SUPERFAMILY SSF81324 6 124 1.31E-27 T 23-10-2018 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 SUPERFAMILY SSF51735 104 252 6.17E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 Gene3D G3DSA:3.40.50.720 106 254 8.7E-27 T 23-10-2018 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 Pfam PF02254 TrkA-N domain 109 229 3.8E-17 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TAM4_1272 ce4d17fd3a762b6580d956c497cc2366 327 Pfam PF07885 Ion channel 17 88 1.7E-17 T 23-10-2018 IPR013099 Potassium channel domain TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 SMART SM00418 44 122 1.1E-23 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 SUPERFAMILY SSF46785 37 121 2.61E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 Gene3D G3DSA:1.10.10.10 12 124 2.4E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 1.5E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 1.5E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 1.5E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.5E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_989 f06e2c0dfa1f414b8d84ca67eaebd3f0 129 Pfam PF01022 Bacterial regulatory protein, arsR family 51 95 1.6E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_2090 ffbd1aaa4132c1bf765dfbd9d47fab58 105 Gene3D G3DSA:3.30.460.10 1 103 4.8E-18 T 23-10-2018 TAM4_2090 ffbd1aaa4132c1bf765dfbd9d47fab58 105 SUPERFAMILY SSF81301 4 105 7.36E-15 T 23-10-2018 TAM4_2090 ffbd1aaa4132c1bf765dfbd9d47fab58 105 Pfam PF01909 Nucleotidyltransferase domain 14 88 9.6E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_2047 c928b51e1ffc983b2c68d68fd8196796 62 Gene3D G3DSA:3.30.300.20 5 61 1.3E-8 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_2047 c928b51e1ffc983b2c68d68fd8196796 62 SUPERFAMILY SSF54814 10 60 2.55E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 301 340 1.4E-4 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 140 179 3.2E-4 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 88 126 1.2E-4 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 SUPERFAMILY SSF50998 20 347 1.96E-18 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 257 287 0.0014 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 570 593 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 SMART SM00220 564 814 6.9E-60 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 675 687 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 Pfam PF00069 Protein kinase domain 564 801 2.1E-49 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 SUPERFAMILY SSF56112 560 807 6.2E-68 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 Gene3D G3DSA:2.80.10.50 232 363 1.8E-5 T 23-10-2018 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 Gene3D G3DSA:1.10.510.10 557 846 3.2E-65 T 23-10-2018 TAM4_947 b39a16e9a465eb98cddee59df76ba888 913 Gene3D G3DSA:2.80.10.50 67 210 2.1E-8 T 23-10-2018 TAM4_2306 a856a3c154826d56bdd1b3d6bcb408c5 350 Pfam PF05763 Protein of unknown function (DUF835) 229 348 5.0E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 325 1.1E-125 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 1.1E-77 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 SUPERFAMILY SSF55205 273 328 7.85E-5 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 SUPERFAMILY SSF55205 4 216 1.96E-63 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 PIRSF PIRSF005378 1 343 3.0E-108 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 Gene3D G3DSA:3.30.360.20 182 276 6.6E-125 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 184 275 8.8E-23 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 SUPERFAMILY SSF52913 185 276 1.2E-23 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 Gene3D G3DSA:3.65.10.20 5 321 6.6E-125 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site TAM4_6 9066e5fa6ab20910e68a945f4e4d66e1 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 39.276 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 SUPERFAMILY SSF48013 9 163 7.06E-25 T 23-10-2018 IPR035926 NusB-like superfamily TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 2.3E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 2.3E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 2.3E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 2.3E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 2.3E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 448 8.6E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 Gene3D G3DSA:3.40.50.150 154 450 1.4E-78 T 23-10-2018 TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 SUPERFAMILY SSF53335 148 450 3.47E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 Gene3D G3DSA:1.10.940.10 6 150 7.6E-16 T 23-10-2018 IPR035926 NusB-like superfamily TAM4_1548 13c70ca276fd9c974730fd1fc75f99e9 451 Pfam PF01029 NusB family 10 133 2.2E-19 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Pfam PF00958 GMP synthase C terminal domain 217 306 2.2E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 SUPERFAMILY SSF54810 189 307 3.53E-45 T 23-10-2018 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 6.0E-152 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Pfam PF02540 NAD synthase 157 186 7.3E-5 T 23-10-2018 IPR022310 NAD/GMP synthase TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Pfam PF02540 NAD synthase 3 83 7.2E-7 T 23-10-2018 IPR022310 NAD/GMP synthase TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 SUPERFAMILY SSF52402 2 224 3.97E-56 T 23-10-2018 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Gene3D G3DSA:3.30.300.10 190 307 5.7E-53 T 23-10-2018 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.843 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TAM4_445 72b06b202fe466a6bc7ceda32b8f2e59 307 Gene3D G3DSA:3.40.50.620 2 189 2.4E-78 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_768 d8142716473eca00a0f88c570888f60f 340 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 6 329 1.5E-86 T 23-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 TAM4_768 d8142716473eca00a0f88c570888f60f 340 Pfam PF03595 Voltage-dependent anion channel 6 326 1.3E-69 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 TAM4_768 d8142716473eca00a0f88c570888f60f 340 Gene3D G3DSA:1.50.10.150 3 332 4.8E-40 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily TAM4_2190 535468e5887fc4b971a5213e4273aa50 193 Pfam PF08241 Methyltransferase domain 39 130 2.5E-25 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TAM4_2190 535468e5887fc4b971a5213e4273aa50 193 Gene3D G3DSA:3.40.50.150 9 179 8.2E-35 T 23-10-2018 TAM4_2190 535468e5887fc4b971a5213e4273aa50 193 SUPERFAMILY SSF53335 10 181 3.35E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1890 b6e747caf531413b4d2be28abad3f2be 245 Gene3D G3DSA:3.30.70.1900 123 241 9.3E-37 T 23-10-2018 TAM4_1890 b6e747caf531413b4d2be28abad3f2be 245 Gene3D G3DSA:3.30.70.1890 1 122 5.6E-38 T 23-10-2018 TAM4_1890 b6e747caf531413b4d2be28abad3f2be 245 Pfam PF01881 CRISPR associated protein Cas6 95 239 2.4E-34 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_1890 b6e747caf531413b4d2be28abad3f2be 245 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 43 238 2.3E-48 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_1890 b6e747caf531413b4d2be28abad3f2be 245 PIRSF PIRSF005054 1 243 1.9E-66 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TAM4_817 a92098a7a49f486576e96521743a08d6 625 Pfam PF05124 S-layer like family, C-terminal region 426 621 1.1E-11 T 23-10-2018 IPR022651 S-layer protein, C-terminal TAM4_817 a92098a7a49f486576e96521743a08d6 625 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 22 621 1.5E-31 T 23-10-2018 IPR006454 S-layer protein GO:0005618 TAM4_817 a92098a7a49f486576e96521743a08d6 625 Pfam PF05123 S-layer like family, N-terminal region 40 325 1.6E-22 T 23-10-2018 IPR022650 S-layer protein, N-terminal TAM4_2344 4c8c7e3ee4ebfed488c90fa43f56b5a8 308 Gene3D G3DSA:1.10.4200.10 25 293 3.2E-60 T 23-10-2018 TAM4_2344 4c8c7e3ee4ebfed488c90fa43f56b5a8 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 14 286 6.3E-48 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 3.8E-130 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 Pfam PF01938 TRAM domain 366 423 1.8E-6 T 23-10-2018 IPR002792 TRAM domain TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 423 1.0E-139 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 Gene3D G3DSA:3.40.50.12160 2 123 1.8E-24 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 9.4E-21 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 Gene3D G3DSA:3.80.30.20 138 369 3.1E-77 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 SUPERFAMILY SSF102114 129 363 1.05E-54 T 23-10-2018 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 SMART SM00729 138 355 4.5E-61 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_358 b302b14a8a1b6cddf81256173fec360d 424 Pfam PF04055 Radical SAM superfamily 142 314 1.2E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1635 27a2922df6e152a313d55f1e8f74eb55 333 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1635 27a2922df6e152a313d55f1e8f74eb55 333 Gene3D G3DSA:3.40.50.300 17 247 1.1E-72 T 23-10-2018 TAM4_1635 27a2922df6e152a313d55f1e8f74eb55 333 SMART SM00382 26 208 1.2E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1635 27a2922df6e152a313d55f1e8f74eb55 333 Pfam PF00005 ABC transporter 21 158 3.0E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1635 27a2922df6e152a313d55f1e8f74eb55 333 SUPERFAMILY SSF52540 5 238 9.25E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_552 ee66ed4ce8839c91fb87c70dc1c6639e 135 SUPERFAMILY SSF88723 1 133 5.61E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_552 ee66ed4ce8839c91fb87c70dc1c6639e 135 Pfam PF01850 PIN domain 4 125 2.4E-17 T 23-10-2018 IPR002716 PIN domain TAM4_552 ee66ed4ce8839c91fb87c70dc1c6639e 135 SMART SM00670 1 125 7.0E-10 T 23-10-2018 IPR002716 PIN domain TAM4_552 ee66ed4ce8839c91fb87c70dc1c6639e 135 Gene3D G3DSA:3.40.50.1010 3 132 3.4E-17 T 23-10-2018 TAM4_910 071f191cd10aa6b6e9ee186e1f7e8ce1 221 SUPERFAMILY SSF52540 5 204 4.75E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_910 071f191cd10aa6b6e9ee186e1f7e8ce1 221 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_910 071f191cd10aa6b6e9ee186e1f7e8ce1 221 SMART SM00382 25 216 9.9E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_910 071f191cd10aa6b6e9ee186e1f7e8ce1 221 Pfam PF00005 ABC transporter 17 152 2.7E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_910 071f191cd10aa6b6e9ee186e1f7e8ce1 221 Gene3D G3DSA:3.40.50.300 1 219 5.0E-48 T 23-10-2018 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 85 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 PIRSF PIRSF006769 1 345 1.1E-109 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 338 1.9E-99 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 Pfam PF01872 RibD C-terminal domain 144 337 4.7E-31 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 SUPERFAMILY SSF53597 144 342 3.17E-44 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 Gene3D G3DSA:3.40.140.10 1 138 6.4E-49 T 23-10-2018 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 97 3.0E-22 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 SUPERFAMILY SSF53927 1 141 1.24E-47 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TAM4_1909 688a166220fa2f52c2fdfd41acb23493 352 Gene3D G3DSA:3.40.430.10 139 347 1.2E-49 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TAM4_1512 59289d02996396d8961673d5c14cea2e 122 Pfam PF00072 Response regulator receiver domain 4 114 3.4E-32 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TAM4_1512 59289d02996396d8961673d5c14cea2e 122 Gene3D G3DSA:3.40.50.12740 2 122 2.2E-40 T 23-10-2018 TAM4_1512 59289d02996396d8961673d5c14cea2e 122 SUPERFAMILY SSF52172 1 119 8.68E-40 T 23-10-2018 IPR011006 CheY-like superfamily TAM4_1512 59289d02996396d8961673d5c14cea2e 122 SMART SM00448 2 114 2.4E-36 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 60 76 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 88 96 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 7 524 5.6E-239 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 Gene3D G3DSA:3.50.7.10 217 368 5.6E-217 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TAM4_436 23523bc80384ed824b9c21b68dc16852 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 34 525 3.5E-183 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 39 51 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 Gene3D G3DSA:1.10.560.10 27 521 5.6E-217 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TAM4_436 23523bc80384ed824b9c21b68dc16852 549 SUPERFAMILY SSF48592 16 525 2.75E-91 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TAM4_436 23523bc80384ed824b9c21b68dc16852 549 Gene3D G3DSA:3.30.260.10 146 404 5.6E-217 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TAM4_436 23523bc80384ed824b9c21b68dc16852 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 88 107 8.8E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 36 52 8.8E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 372 394 8.8E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 58 76 8.8E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 406 418 8.8E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TAM4_436 23523bc80384ed824b9c21b68dc16852 549 SUPERFAMILY SSF54849 147 404 3.05E-31 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TAM4_436 23523bc80384ed824b9c21b68dc16852 549 SUPERFAMILY SSF52029 211 377 1.76E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TAM4_447 9772933a43e85a91460d79775c9c16ba 348 SUPERFAMILY SSF53187 4 343 6.72E-72 T 23-10-2018 TAM4_447 9772933a43e85a91460d79775c9c16ba 348 Gene3D G3DSA:3.40.630.10 6 336 1.8E-137 T 23-10-2018 TAM4_447 9772933a43e85a91460d79775c9c16ba 348 SUPERFAMILY SSF101821 68 177 5.04E-30 T 23-10-2018 TAM4_447 9772933a43e85a91460d79775c9c16ba 348 Gene3D G3DSA:2.40.30.40 68 161 1.8E-137 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TAM4_447 9772933a43e85a91460d79775c9c16ba 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 3.9E-112 T 23-10-2018 IPR008007 Peptidase M42 TAM4_447 9772933a43e85a91460d79775c9c16ba 348 PIRSF PIRSF001123 1 347 1.1E-122 T 23-10-2018 IPR008007 Peptidase M42 TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 Gene3D G3DSA:3.40.800.20 3 329 9.4E-81 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 1.9E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 1.9E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 1.9E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 SUPERFAMILY SSF52768 5 333 1.97E-88 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TAM4_469 a5d8d37eafce4a4642b2a354b497f3e1 334 Pfam PF00850 Histone deacetylase domain 21 288 1.9E-67 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 Pfam PF00571 CBS domain 6 59 3.6E-12 T 23-10-2018 IPR000644 CBS domain TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 Pfam PF00571 CBS domain 71 124 1.5E-12 T 23-10-2018 IPR000644 CBS domain TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 SMART SM00116 78 125 2.3E-8 T 23-10-2018 IPR000644 CBS domain TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 SMART SM00116 13 60 3.9E-8 T 23-10-2018 IPR000644 CBS domain TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 Gene3D G3DSA:3.10.580.10 2 173 8.7E-42 T 23-10-2018 TAM4_1547 15d5d3696f583a0b51d4c97272a8db37 175 SUPERFAMILY SSF54631 3 132 1.64E-32 T 23-10-2018 TAM4_591 6704577d019cbaa9e06fba5ef3388ab0 154 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 140 4.2E-54 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_591 6704577d019cbaa9e06fba5ef3388ab0 154 Pfam PF01967 MoaC family 13 151 8.7E-51 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_591 6704577d019cbaa9e06fba5ef3388ab0 154 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 8 153 38.945 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 TAM4_591 6704577d019cbaa9e06fba5ef3388ab0 154 SUPERFAMILY SSF55040 11 152 2.62E-50 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_591 6704577d019cbaa9e06fba5ef3388ab0 154 Gene3D G3DSA:3.30.70.640 1 154 1.5E-67 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TAM4_818 7c63ca54a1bd90e3924ef8c2a61b9802 273 SMART SM00382 26 205 6.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_818 7c63ca54a1bd90e3924ef8c2a61b9802 273 Gene3D G3DSA:3.40.50.300 1 220 3.2E-45 T 23-10-2018 TAM4_818 7c63ca54a1bd90e3924ef8c2a61b9802 273 Pfam PF00005 ABC transporter 27 154 8.6E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_818 7c63ca54a1bd90e3924ef8c2a61b9802 273 SUPERFAMILY SSF52540 3 211 8.58E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_723 fcdb172845f3a1f50b681e929f262353 273 PIRSF PIRSF016210 1 273 4.4E-82 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TAM4_723 fcdb172845f3a1f50b681e929f262353 273 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 272 35.943 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TAM4_723 fcdb172845f3a1f50b681e929f262353 273 Pfam PF04414 D-aminoacyl-tRNA deacylase 69 270 2.0E-67 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 TAM4_723 fcdb172845f3a1f50b681e929f262353 273 Gene3D G3DSA:3.40.630.50 1 187 2.1E-69 T 23-10-2018 TAM4_723 fcdb172845f3a1f50b681e929f262353 273 Gene3D G3DSA:3.40.50.10700 188 273 9.5E-31 T 23-10-2018 TAM4_723 fcdb172845f3a1f50b681e929f262353 273 SUPERFAMILY SSF142535 1 271 3.14E-88 T 23-10-2018 TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 Gene3D G3DSA:3.30.870.10 122 264 6.6E-80 T 23-10-2018 TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 SUPERFAMILY SSF46785 10 96 7.18E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 125 262 6.6E-8 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TAM4_1705 8c49b2b972c4205a44cfe71c6ad42add 264 SUPERFAMILY SSF56024 142 262 9.16E-7 T 23-10-2018 TAM4_1831 7debbd802435e13a59ffaaa6cbee18a6 241 Gene3D G3DSA:3.40.800.10 23 240 7.1E-19 T 23-10-2018 TAM4_1831 7debbd802435e13a59ffaaa6cbee18a6 241 Pfam PF00491 Arginase family 51 224 5.5E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TAM4_1831 7debbd802435e13a59ffaaa6cbee18a6 241 PIRSF PIRSF036979 28 231 1.0E-13 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TAM4_1831 7debbd802435e13a59ffaaa6cbee18a6 241 SUPERFAMILY SSF52768 3 225 9.18E-27 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 4.2E-22 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 7.3E-147 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 SUPERFAMILY SSF51246 327 417 1.65E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Gene3D G3DSA:3.30.470.20 189 328 2.2E-46 T 23-10-2018 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 SMART SM01210 328 418 1.8E-20 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Gene3D G3DSA:3.40.50.20 2 94 1.1E-21 T 23-10-2018 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 SUPERFAMILY SSF56059 103 319 1.08E-47 T 23-10-2018 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Gene3D G3DSA:3.30.1490.20 121 187 2.8E-15 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Gene3D G3DSA:3.90.600.10 329 428 1.7E-9 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 SMART SM01209 102 296 9.4E-96 T 23-10-2018 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 36.299 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 7.9E-60 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 2.2E-13 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_774 d0c1be75c4b61fb9dc44b5c060807b1f 438 SUPERFAMILY SSF52440 1 102 2.01E-24 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TAM4_1721 74d99f200abe976685cc3589d06635a1 548 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 327 340 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TAM4_1721 74d99f200abe976685cc3589d06635a1 548 SUPERFAMILY SSF53383 100 522 1.21E-48 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_1721 74d99f200abe976685cc3589d06635a1 548 Gene3D G3DSA:1.10.20.110 49 419 2.5E-201 T 23-10-2018 TAM4_1721 74d99f200abe976685cc3589d06635a1 548 Gene3D G3DSA:3.90.1150.10 42 538 2.5E-201 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1721 74d99f200abe976685cc3589d06635a1 548 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 23 539 1.2E-217 T 23-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TAM4_1721 74d99f200abe976685cc3589d06635a1 548 Gene3D G3DSA:3.40.640.10 177 397 2.5E-201 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1721 74d99f200abe976685cc3589d06635a1 548 Pfam PF00155 Aminotransferase class I and II 186 519 2.3E-23 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.716 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 SMART SM01384 2 191 1.3E-134 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 SUPERFAMILY SSF54189 1 191 2.21E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 Pfam PF00827 Ribosomal L15 2 189 5.6E-90 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_45 918fafdb1eda16a7c9d476a2618f6a2f 194 Gene3D G3DSA:3.40.1120.10 1 193 2.4E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 Gene3D G3DSA:3.40.50.10800 173 257 3.5E-123 T 23-10-2018 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 SUPERFAMILY SSF142754 6 301 6.15E-114 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 4.7E-111 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.018 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 Gene3D G3DSA:3.40.50.10800 88 300 3.5E-123 T 23-10-2018 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 Gene3D G3DSA:3.40.50.10800 8 282 3.5E-123 T 23-10-2018 TAM4_756 2d6a79ce0551bb96ef4228eee2952701 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 4 302 1.3E-112 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TAM4_1703 d44669c081c67c8df7a37e41a51e2f3c 390 Gene3D G3DSA:1.25.40.10 47 112 1.9E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1703 d44669c081c67c8df7a37e41a51e2f3c 390 Gene3D G3DSA:1.25.40.10 4 46 4.0E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_874 a1e13e061a0c5c35f0f373c63f61c89c 126 Pfam PF01042 Endoribonuclease L-PSP 11 125 1.3E-39 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TAM4_874 a1e13e061a0c5c35f0f373c63f61c89c 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TAM4_874 a1e13e061a0c5c35f0f373c63f61c89c 126 Gene3D G3DSA:3.30.1330.40 9 126 3.2E-46 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TAM4_874 a1e13e061a0c5c35f0f373c63f61c89c 126 SUPERFAMILY SSF55298 5 126 3.61E-40 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TAM4_874 a1e13e061a0c5c35f0f373c63f61c89c 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 13 125 1.2E-42 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Gene3D G3DSA:3.10.580.10 123 281 1.5E-36 T 23-10-2018 TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SUPERFAMILY SSF54631 1 118 7.07E-28 T 23-10-2018 TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SUPERFAMILY SSF54631 124 278 5.43E-32 T 23-10-2018 TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Gene3D G3DSA:3.10.580.10 1 122 1.4E-39 T 23-10-2018 TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SMART SM00116 10 59 2.9E-5 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SMART SM00116 231 279 4.8E-11 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SMART SM00116 136 184 1.7 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 SMART SM00116 70 118 3.2E-10 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Pfam PF00571 CBS domain 135 181 3.1E-5 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Pfam PF00571 CBS domain 67 116 7.2E-13 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Pfam PF00571 CBS domain 3 55 1.5E-7 T 23-10-2018 IPR000644 CBS domain TAM4_261 4ce94860e806d7d45099925cb0b1f641 281 Pfam PF00571 CBS domain 224 279 3.0E-13 T 23-10-2018 IPR000644 CBS domain TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 Gene3D G3DSA:1.10.510.10 156 257 4.5E-26 T 23-10-2018 TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 Pfam PF01163 RIO1 family 65 248 1.4E-53 T 23-10-2018 TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 SMART SM00090 23 257 1.6E-114 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 SUPERFAMILY SSF56112 45 249 2.99E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TAM4_1631 7c5e5bfdfa234290eb309499bc58b71b 258 Gene3D G3DSA:3.30.200.20 51 151 1.9E-12 T 23-10-2018 TAM4_1255 f76dcf19074eb047c42ff03c162e630e 146 Pfam PF13187 4Fe-4S dicluster domain 45 91 1.9E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1255 f76dcf19074eb047c42ff03c162e630e 146 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1255 f76dcf19074eb047c42ff03c162e630e 146 SUPERFAMILY SSF54862 27 112 3.05E-22 T 23-10-2018 TAM4_1255 f76dcf19074eb047c42ff03c162e630e 146 Gene3D G3DSA:3.30.70.3270 23 146 3.4E-21 T 23-10-2018 TAM4_1137 27e275417b69de2e50e5c95cdb99e490 358 Gene3D G3DSA:1.20.81.30 176 285 1.9E-12 T 23-10-2018 TAM4_1137 27e275417b69de2e50e5c95cdb99e490 358 Pfam PF00482 Type II secretion system (T2SS), protein F 185 309 2.5E-23 T 23-10-2018 IPR018076 Type II secretion system F domain TAM4_391 fe5dda0254288c378879a0d3623fe32d 245 SUPERFAMILY SSF52540 1 235 6.86E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_391 fe5dda0254288c378879a0d3623fe32d 245 Pfam PF13614 AAA domain 3 145 6.2E-31 T 23-10-2018 IPR025669 AAA domain TAM4_391 fe5dda0254288c378879a0d3623fe32d 245 Gene3D G3DSA:3.40.50.300 1 235 6.6E-76 T 23-10-2018 TAM4_391 fe5dda0254288c378879a0d3623fe32d 245 PIRSF PIRSF003092 1 241 5.6E-58 T 23-10-2018 IPR025501 ATP binding protein MinD TAM4_391 fe5dda0254288c378879a0d3623fe32d 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 236 3.4E-105 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 SUPERFAMILY SSF46785 49 122 5.78E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 Pfam PF01022 Bacterial regulatory protein, arsR family 62 108 3.0E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 SMART SM00418 55 133 9.5E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 4.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 4.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1944 33834b5fe03fc013dac8a5e3923e38bb 136 Gene3D G3DSA:1.10.10.10 31 124 2.4E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1094 799d0191a2cde59e30b2d64c6105df4e 369 SUPERFAMILY SSF53448 1 249 2.09E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1094 799d0191a2cde59e30b2d64c6105df4e 369 Pfam PF00535 Glycosyl transferase family 2 4 165 2.5E-28 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_1094 799d0191a2cde59e30b2d64c6105df4e 369 Gene3D G3DSA:3.90.550.10 1 223 1.2E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_313 d0b24e29103e351860a842ada45f6bc6 308 SUPERFAMILY SSF53448 19 274 6.27E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_313 d0b24e29103e351860a842ada45f6bc6 308 Gene3D G3DSA:3.90.550.10 7 226 1.3E-22 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_313 d0b24e29103e351860a842ada45f6bc6 308 Pfam PF00535 Glycosyl transferase family 2 20 163 1.8E-14 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_816 9fdeb08deccc6de5cc5dcf811266eb2f 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 285 7.2E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_816 9fdeb08deccc6de5cc5dcf811266eb2f 299 Gene3D G3DSA:1.10.3720.10 54 296 4.3E-52 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_816 9fdeb08deccc6de5cc5dcf811266eb2f 299 SUPERFAMILY SSF160964 9 42 3.53E-7 T 23-10-2018 TAM4_816 9fdeb08deccc6de5cc5dcf811266eb2f 299 SUPERFAMILY SSF161098 58 286 3.14E-46 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 9.1E-116 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 2.8E-50 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 SUPERFAMILY SSF52166 1 252 1.44E-72 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 Gene3D G3DSA:3.40.1370.10 1 255 1.5E-99 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_244 d3415a54b3dabfcb5ac1833ffcc22bcb 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.676 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 SUPERFAMILY SSF56784 1 228 1.53E-41 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 222 1.3E-76 T 23-10-2018 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 196 1.6E-16 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 139 224 1.6E-18 T 23-10-2018 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 78 3.7E-7 T 23-10-2018 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 Hamap MF_01419 Phosphoglycolate phosphatase. 2 229 33.016 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 Gene3D G3DSA:3.40.50.1000 3 223 1.1E-73 T 23-10-2018 IPR023214 HAD superfamily TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 232 1.2E-73 T 23-10-2018 TAM4_1868 847341e61d18c88bc7ac2d1f7d11bfbd 245 Gene3D G3DSA:3.90.1070.10 86 153 1.1E-73 T 23-10-2018 TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 15 325 2.9E-113 T 23-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 Gene3D G3DSA:3.40.50.1100 53 156 1.9E-117 T 23-10-2018 TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 PIRSF PIRSF006278 4 331 5.0E-87 T 23-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 313 1.2E-41 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 SUPERFAMILY SSF53686 10 321 3.7E-77 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TAM4_1367 fcc433712e6101d5d256c28c9b55e2a1 332 Gene3D G3DSA:3.40.50.1100 14 317 1.9E-117 T 23-10-2018 TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 9.4E-63 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 Gene3D G3DSA:3.40.50.620 1 235 9.4E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 4.0E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 45.544 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 PIRSF PIRSF006293 1 238 6.7E-70 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_1276 84995be71a7c14d52150083e12c4cf60 239 SUPERFAMILY SSF52402 1 235 1.21E-50 T 23-10-2018 TAM4_2122 79a24c876886faf7f462584bf29d1457 125 SUPERFAMILY SSF88723 1 121 3.08E-31 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2122 79a24c876886faf7f462584bf29d1457 125 Pfam PF01850 PIN domain 2 114 1.5E-18 T 23-10-2018 IPR002716 PIN domain TAM4_2122 79a24c876886faf7f462584bf29d1457 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 121 12.295 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_2122 79a24c876886faf7f462584bf29d1457 125 Gene3D G3DSA:3.40.50.1010 1 121 2.7E-28 T 23-10-2018 TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 6.1E-141 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 Gene3D G3DSA:3.80.30.20 163 389 3.7E-37 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 SUPERFAMILY SSF102114 156 377 6.15E-39 T 23-10-2018 TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 Pfam PF04055 Radical SAM superfamily 168 338 5.2E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 Gene3D G3DSA:3.40.50.280 3 123 2.3E-24 T 23-10-2018 TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 Pfam PF02310 B12 binding domain 19 112 6.0E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TAM4_1823 77bedf4c7d6363af5c53d223e221e694 424 SMART SM00729 164 382 1.7E-47 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Gene3D G3DSA:2.40.50.140 1 81 1.6E-31 T 23-10-2018 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 SUPERFAMILY SSF50249 2 92 1.23E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 1.4E-21 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 PIRSF PIRSF002158 1 239 8.6E-74 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.569 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 SMART SM01382 91 223 4.9E-63 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Gene3D G3DSA:2.30.30.30 85 162 2.6E-31 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 SUPERFAMILY SSF50104 94 237 7.22E-49 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 SMART SM01383 11 85 1.7E-28 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_321 b2a2ca4ea2798540e119d3692eed85c3 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 222 6.9E-44 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TAM4_349 7ef0fd63ecb4f5573bbfe398ff6781c8 267 SUPERFAMILY SSF53335 36 208 1.23E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_349 7ef0fd63ecb4f5573bbfe398ff6781c8 267 Gene3D G3DSA:3.40.50.150 26 253 7.3E-20 T 23-10-2018 TAM4_349 7ef0fd63ecb4f5573bbfe398ff6781c8 267 Pfam PF13649 Methyltransferase domain 51 145 3.9E-7 T 23-10-2018 TAM4_1711 e46c38091756cfdf042c2624d4f3ad6f 144 SUPERFAMILY SSF102712 2 127 7.59E-23 T 23-10-2018 TAM4_1711 e46c38091756cfdf042c2624d4f3ad6f 144 SMART SM00232 1 122 4.0E-13 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TAM4_1711 e46c38091756cfdf042c2624d4f3ad6f 144 Gene3D G3DSA:3.40.140.10 5 140 3.7E-30 T 23-10-2018 TAM4_1711 e46c38091756cfdf042c2624d4f3ad6f 144 Pfam PF14464 Prokaryotic homologs of the JAB domain 16 119 4.5E-18 T 23-10-2018 IPR028090 JAB domain, prokaryotic TAM4_2191 898b99b5ef47a4cf6f54ad3a5acc29c2 242 SUPERFAMILY SSF52540 3 214 1.73E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2191 898b99b5ef47a4cf6f54ad3a5acc29c2 242 Pfam PF00005 ABC transporter 23 167 2.0E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2191 898b99b5ef47a4cf6f54ad3a5acc29c2 242 Gene3D G3DSA:3.40.50.300 1 227 3.5E-53 T 23-10-2018 TAM4_2191 898b99b5ef47a4cf6f54ad3a5acc29c2 242 SMART SM00382 32 216 6.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_2191 898b99b5ef47a4cf6f54ad3a5acc29c2 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 Gene3D G3DSA:1.10.10.10 235 299 3.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 SUPERFAMILY SSF52540 3 239 1.92E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 Gene3D G3DSA:3.40.50.300 3 164 3.2E-31 T 23-10-2018 TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 SUPERFAMILY SSF46785 217 351 4.01E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 Pfam PF03008 Archaea bacterial proteins of unknown function 307 403 1.2E-28 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_176 44d71399b5def0bc4aacc3cc5ce85291 453 Pfam PF01637 ATPase domain predominantly from Archaea 5 198 4.9E-22 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Gene3D G3DSA:3.40.120.10 1 147 4.9E-51 T 23-10-2018 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 SUPERFAMILY SSF53738 150 249 1.88E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 435 5.1E-8 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.64 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 SUPERFAMILY SSF53738 3 171 2.39E-45 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 246 2.6E-18 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Gene3D G3DSA:3.40.120.10 247 330 1.6E-53 T 23-10-2018 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 442 2.6E-161 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Gene3D G3DSA:3.30.310.50 360 448 3.5E-22 T 23-10-2018 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 9.3E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Gene3D G3DSA:3.40.120.10 165 345 1.6E-53 T 23-10-2018 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 SUPERFAMILY SSF53738 252 355 1.33E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 1.3E-44 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 SUPERFAMILY SSF55957 348 446 7.59E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 1.7E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 1.7E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_134 72c692d32a52c8b2f597d923f98b450e 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 1.7E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_986 52dc0cfcd4f6140986bd1f8c4e7b3797 326 Gene3D G3DSA:3.40.50.10490 3 162 9.1E-38 T 23-10-2018 TAM4_986 52dc0cfcd4f6140986bd1f8c4e7b3797 326 Gene3D G3DSA:3.40.50.10490 164 312 5.3E-45 T 23-10-2018 TAM4_986 52dc0cfcd4f6140986bd1f8c4e7b3797 326 Pfam PF01380 SIS domain 191 306 4.4E-9 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TAM4_986 52dc0cfcd4f6140986bd1f8c4e7b3797 326 Pfam PF01380 SIS domain 36 153 4.7E-12 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TAM4_986 52dc0cfcd4f6140986bd1f8c4e7b3797 326 SUPERFAMILY SSF53697 2 325 3.87E-61 T 23-10-2018 TAM4_731 a3f6274aae63f77d6c2f469106eab1d1 248 Pfam PF03167 Uracil DNA glycosylase superfamily 109 211 4.4E-21 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_731 a3f6274aae63f77d6c2f469106eab1d1 248 Gene3D G3DSA:3.40.470.10 88 243 2.2E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_731 a3f6274aae63f77d6c2f469106eab1d1 248 SMART SM00987 104 238 5.3E-11 T 23-10-2018 TAM4_731 a3f6274aae63f77d6c2f469106eab1d1 248 SUPERFAMILY SSF52141 102 239 7.19E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_731 a3f6274aae63f77d6c2f469106eab1d1 248 SMART SM00986 104 238 5.3E-11 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_1353 1860b63bc5e736be89d82bf7f5290b91 222 Gene3D G3DSA:1.20.58.220 1 222 6.5E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily TAM4_1353 1860b63bc5e736be89d82bf7f5290b91 222 SUPERFAMILY SSF109755 24 219 2.83E-18 T 23-10-2018 TAM4_1353 1860b63bc5e736be89d82bf7f5290b91 222 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 4 220 7.3E-35 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TAM4_1353 1860b63bc5e736be89d82bf7f5290b91 222 Pfam PF01865 Protein of unknown function DUF47 4 220 2.4E-46 T 23-10-2018 IPR018445 Putative phosphate transport regulator TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 Gene3D G3DSA:3.40.50.720 1 136 4.0E-51 T 23-10-2018 TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 SUPERFAMILY SSF52540 4 342 5.84E-91 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 PIRSF PIRSF026760 2 348 1.8E-118 T 23-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 Gene3D G3DSA:3.40.50.300 141 344 8.2E-57 T 23-10-2018 TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 39 134 9.3E-32 T 23-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain TAM4_1749 2005f5feea4e285b9261c6cd6bd2476e 361 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 143 338 1.6E-58 T 23-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 Gene3D G3DSA:3.40.50.720 95 286 8.9E-113 T 23-10-2018 TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 SUPERFAMILY SSF51735 100 286 2.45E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 SUPERFAMILY SSF52283 1 132 1.81E-32 T 23-10-2018 TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 286 8.8E-54 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 Gene3D G3DSA:3.40.50.720 16 318 8.9E-113 T 23-10-2018 TAM4_909 b0a55fff8178b5fcc533a10b96fd76c1 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 318 7.4E-32 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TAM4_58 f6944cae22cb5aee9a5248146883938b 158 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 130 2.6E-14 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC TAM4_58 f6944cae22cb5aee9a5248146883938b 158 SUPERFAMILY SSF56784 2 146 2.0E-18 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_58 f6944cae22cb5aee9a5248146883938b 158 Pfam PF03031 NLI interacting factor-like phosphatase 3 156 1.5E-7 T 23-10-2018 IPR004274 FCP1 homology domain TAM4_58 f6944cae22cb5aee9a5248146883938b 158 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 152 1.3E-23 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 TAM4_58 f6944cae22cb5aee9a5248146883938b 158 Gene3D G3DSA:3.40.50.1000 1 157 2.3E-26 T 23-10-2018 IPR023214 HAD superfamily TAM4_2078 be9a4ed4383408a49d2c1658e4beda2f 65 SMART SM00530 4 59 2.1E-21 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_2078 be9a4ed4383408a49d2c1658e4beda2f 65 Gene3D G3DSA:1.10.260.40 1 64 1.7E-31 T 23-10-2018 TAM4_2078 be9a4ed4383408a49d2c1658e4beda2f 65 Pfam PF01381 Helix-turn-helix 5 58 3.5E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_2078 be9a4ed4383408a49d2c1658e4beda2f 65 SUPERFAMILY SSF47413 3 64 2.95E-21 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_1698 feff2ca9e22383b109f2d8b581a531f4 159 Pfam PF09638 Ph1570 protein 1 155 1.5E-78 T 23-10-2018 IPR023110 PH1570-like domain TAM4_1698 feff2ca9e22383b109f2d8b581a531f4 159 SUPERFAMILY SSF159902 1 155 2.75E-74 T 23-10-2018 TAM4_1698 feff2ca9e22383b109f2d8b581a531f4 159 Gene3D G3DSA:3.40.1600.10 1 156 8.1E-76 T 23-10-2018 IPR036807 PH1570-like superfamily TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 SUPERFAMILY SSF56300 257 486 1.73E-32 T 23-10-2018 TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 SUPERFAMILY SSF56300 2 235 1.55E-50 T 23-10-2018 TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 287 473 4.2E-7 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 Pfam PF00149 Calcineurin-like phosphoesterase 2 185 8.3E-20 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 Gene3D G3DSA:3.60.21.10 1 251 1.8E-40 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_801 d5a92eeb2a169042f15e5341112acc04 500 Gene3D G3DSA:3.60.21.10 252 493 5.2E-23 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_566 d7973db8ac96d19cbcbfb2ff90a5a0bc 124 SUPERFAMILY SSF46785 51 121 8.94E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_566 d7973db8ac96d19cbcbfb2ff90a5a0bc 124 Gene3D G3DSA:1.10.10.10 54 123 5.3E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_566 d7973db8ac96d19cbcbfb2ff90a5a0bc 124 Gene3D G3DSA:1.10.8.60 1 53 1.3E-13 T 23-10-2018 TAM4_1351 478f6c34d091a076a5198460bf576534 195 Hamap MF_00582 UPF0215 protein . 9 189 34.474 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TAM4_1351 478f6c34d091a076a5198460bf576534 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 1.0E-41 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TAM4_1351 478f6c34d091a076a5198460bf576534 195 Gene3D G3DSA:3.30.2170.10 3 195 8.1E-63 T 23-10-2018 TAM4_1351 478f6c34d091a076a5198460bf576534 195 PIRSF PIRSF006380 1 195 8.1E-71 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TAM4_1351 478f6c34d091a076a5198460bf576534 195 Pfam PF01949 Protein of unknown function DUF99 8 188 1.2E-66 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 368 2.1E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 SUPERFAMILY SSF52922 258 376 2.62E-34 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 Gene3D G3DSA:3.40.50.920 256 394 1.5E-41 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 Gene3D G3DSA:3.40.50.970 7 254 2.4E-97 T 23-10-2018 TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 241 1.1E-76 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_1460 9d3b6f0f3cd25f9a45806168a6f9ebd8 394 SUPERFAMILY SSF52518 8 253 3.12E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 SUPERFAMILY SSF52540 4 248 1.29E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 Pfam PF09339 IclR helix-turn-helix domain 249 292 6.1E-7 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 Gene3D G3DSA:1.10.10.10 246 294 5.2E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 Pfam PF01637 ATPase domain predominantly from Archaea 6 208 9.3E-26 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 Gene3D G3DSA:3.40.50.300 1 173 3.6E-32 T 23-10-2018 TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 Pfam PF03008 Archaea bacterial proteins of unknown function 318 414 8.3E-27 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_2169 edd15f7493e8f521c74406b6bfff023d 484 SUPERFAMILY SSF46785 248 326 2.82E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1509 c7a133463ff7bbb27b3c2d35345355cb 388 SUPERFAMILY SSF103473 9 379 7.59E-22 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1509 c7a133463ff7bbb27b3c2d35345355cb 388 Gene3D G3DSA:1.20.1250.20 3 382 3.2E-19 T 23-10-2018 TAM4_1509 c7a133463ff7bbb27b3c2d35345355cb 388 Pfam PF07690 Major Facilitator Superfamily 12 344 8.1E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_2106 46f2d0b19ac1875a783700d9cb9cfeaa 1351 SUPERFAMILY SSF82866 781 962 3.27E-24 T 23-10-2018 TAM4_2106 46f2d0b19ac1875a783700d9cb9cfeaa 1351 SUPERFAMILY SSF82866 1134 1341 1.31E-20 T 23-10-2018 TAM4_2106 46f2d0b19ac1875a783700d9cb9cfeaa 1351 Pfam PF03176 MMPL family 777 976 1.3E-34 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TAM4_2106 46f2d0b19ac1875a783700d9cb9cfeaa 1351 Pfam PF03176 MMPL family 1025 1341 1.3E-30 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TAM4_274 822497c1b3bbbe612b400b46be574f70 252 Gene3D G3DSA:1.10.8.60 92 168 1.6E-16 T 23-10-2018 TAM4_274 822497c1b3bbbe612b400b46be574f70 252 Gene3D G3DSA:3.40.50.300 2 91 1.5E-11 T 23-10-2018 TAM4_274 822497c1b3bbbe612b400b46be574f70 252 SUPERFAMILY SSF52540 13 159 3.13E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1566 0efcb9ad029e9d6e445b8165a1e90aaf 89 Pfam PF11848 Domain of unknown function (DUF3368) 41 83 1.6E-9 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 Gene3D G3DSA:3.40.30.10 1 144 1.4E-45 T 23-10-2018 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 SUPERFAMILY SSF52833 1 215 4.75E-64 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 PIRSF PIRSF000239 1 215 1.4E-71 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 4.5E-9 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 Hamap MF_00401 Peroxiredoxin. 2 215 51.894 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 Gene3D G3DSA:3.30.1020.10 145 216 1.4E-33 T 23-10-2018 TAM4_2096 324e2025826ebe7b772cbbd5b272dc33 216 Pfam PF00578 AhpC/TSA family 4 134 2.6E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TAM4_1791 4a5b394066d9f695309ae5aceacf7eac 340 Gene3D G3DSA:3.40.190.10 118 284 2.0E-133 T 23-10-2018 TAM4_1791 4a5b394066d9f695309ae5aceacf7eac 340 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 31 302 1.4E-125 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 TAM4_1791 4a5b394066d9f695309ae5aceacf7eac 340 Gene3D G3DSA:3.40.190.10 32 333 2.0E-133 T 23-10-2018 TAM4_1791 4a5b394066d9f695309ae5aceacf7eac 340 SUPERFAMILY SSF53850 29 331 2.34E-53 T 23-10-2018 TAM4_1791 4a5b394066d9f695309ae5aceacf7eac 340 Pfam PF13531 Bacterial extracellular solute-binding protein 34 314 6.3E-37 T 23-10-2018 TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 SUPERFAMILY SSF50249 3 69 5.83E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.038 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 2.0E-12 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 Pfam PF01200 Ribosomal protein S28e 4 66 8.4E-30 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_89 869f8b6e9c71c7ba7e656fbad5625233 70 Gene3D G3DSA:2.40.50.140 1 70 3.2E-32 T 23-10-2018 TAM4_111 fba8496dd259a4f82e6ea86e32a24cf1 513 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 477 2.1E-17 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TAM4_111 fba8496dd259a4f82e6ea86e32a24cf1 513 Pfam PF01943 Polysaccharide biosynthesis protein 12 283 1.6E-33 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TAM4_1734 1b67e3cc804f4650ae324f3fa8926333 324 Gene3D G3DSA:3.40.50.150 140 312 3.7E-27 T 23-10-2018 TAM4_1734 1b67e3cc804f4650ae324f3fa8926333 324 SUPERFAMILY SSF53335 136 308 4.18E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1734 1b67e3cc804f4650ae324f3fa8926333 324 Pfam PF13649 Methyltransferase domain 165 260 1.0E-13 T 23-10-2018 TAM4_496 74d698e9e77c414123801d369531d83b 339 Pfam PF00709 Adenylosuccinate synthetase 150 289 1.2E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TAM4_496 74d698e9e77c414123801d369531d83b 339 Pfam PF00709 Adenylosuccinate synthetase 5 148 2.5E-37 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TAM4_496 74d698e9e77c414123801d369531d83b 339 SMART SM00788 3 334 5.9E-157 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TAM4_496 74d698e9e77c414123801d369531d83b 339 SUPERFAMILY SSF52540 1 335 1.81E-107 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_496 74d698e9e77c414123801d369531d83b 339 Gene3D G3DSA:3.40.440.10 1 339 5.4E-138 T 23-10-2018 TAM4_496 74d698e9e77c414123801d369531d83b 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TAM4_496 74d698e9e77c414123801d369531d83b 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 98.622 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TAM4_1713 163b5d78957895a3ab9e65ab7f3bfeac 430 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 271 418 1.2E-30 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TAM4_1713 163b5d78957895a3ab9e65ab7f3bfeac 430 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 34 167 1.7E-17 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TAM4_1713 163b5d78957895a3ab9e65ab7f3bfeac 430 Gene3D G3DSA:3.40.50.2300 260 388 2.1E-43 T 23-10-2018 TAM4_1713 163b5d78957895a3ab9e65ab7f3bfeac 430 Gene3D G3DSA:3.40.50.2300 21 147 1.2E-27 T 23-10-2018 TAM4_701 db68cbdf7fc464f8f839d4ef74c05ee2 264 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 151 4.6E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_701 db68cbdf7fc464f8f839d4ef74c05ee2 264 SUPERFAMILY SSF56770 4 211 1.83E-45 T 23-10-2018 TAM4_701 db68cbdf7fc464f8f839d4ef74c05ee2 264 Gene3D G3DSA:3.40.50.700 4 164 1.3E-41 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TAM4_2213 badda15ed1941a5fbdba75ac37017374 125 Gene3D G3DSA:1.10.10.10 2 83 1.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_2213 badda15ed1941a5fbdba75ac37017374 125 SUPERFAMILY SSF46785 4 113 2.24E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2213 badda15ed1941a5fbdba75ac37017374 125 Pfam PF01475 Ferric uptake regulator family 14 122 4.5E-20 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TAM4_1680 d0bc45fb652ca412e9d02aec452af90c 159 Pfam PF10130 PIN domain 4 131 7.1E-25 T 23-10-2018 IPR002716 PIN domain TAM4_1680 d0bc45fb652ca412e9d02aec452af90c 159 SUPERFAMILY SSF88723 1 118 8.69E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1680 d0bc45fb652ca412e9d02aec452af90c 159 Gene3D G3DSA:3.40.50.1010 1 122 1.3E-7 T 23-10-2018 TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 Pfam PF00069 Protein kinase domain 200 436 6.7E-49 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 206 228 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 Gene3D G3DSA:1.10.510.10 189 460 8.8E-67 T 23-10-2018 TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 SUPERFAMILY SSF56112 190 442 1.31E-70 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 SMART SM00220 200 445 1.2E-54 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TAM4_720 cd9c2aa1dcea3123df99ff68f70613ea 538 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 310 322 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TAM4_1448 e0ac2d4ac4f242bc02a969d4e53861e6 161 SUPERFAMILY SSF46785 1 97 1.04E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1448 e0ac2d4ac4f242bc02a969d4e53861e6 161 Gene3D G3DSA:1.10.10.10 1 61 7.8E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1448 e0ac2d4ac4f242bc02a969d4e53861e6 161 SMART SM00418 1 62 0.0011 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1448 e0ac2d4ac4f242bc02a969d4e53861e6 161 Pfam PF01022 Bacterial regulatory protein, arsR family 1 39 2.7E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 4.3E-10 T 23-10-2018 TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.3E-10 T 23-10-2018 TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 4.3E-10 T 23-10-2018 TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 SUPERFAMILY SSF51905 3 283 1.17E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 Pfam PF01494 FAD binding domain 3 279 8.0E-13 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 Gene3D G3DSA:3.50.50.60 1 366 1.6E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1256 1da8b195cd088d898b59554a33bf26b2 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 278 7.4E-51 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TAM4_660 efac212315078f15617456da731d1cef 335 Gene3D G3DSA:3.40.910.10 2 335 1.9E-144 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TAM4_660 efac212315078f15617456da731d1cef 335 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 333 42.402 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 TAM4_660 efac212315078f15617456da731d1cef 335 SUPERFAMILY SSF52467 5 333 4.58E-115 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TAM4_660 efac212315078f15617456da731d1cef 335 Pfam PF01916 Deoxyhypusine synthase 34 330 4.8E-113 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TAM4_660 efac212315078f15617456da731d1cef 335 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 334 8.3E-122 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TAM4_1757 34d63d540200175baa555fba28ce690b 428 Gene3D G3DSA:3.90.220.20 2 190 2.1E-44 T 23-10-2018 TAM4_1757 34d63d540200175baa555fba28ce690b 428 SUPERFAMILY SSF116734 12 212 4.91E-50 T 23-10-2018 TAM4_1757 34d63d540200175baa555fba28ce690b 428 SUPERFAMILY SSF116734 215 426 1.19E-46 T 23-10-2018 TAM4_1757 34d63d540200175baa555fba28ce690b 428 Gene3D G3DSA:3.90.220.20 211 377 5.3E-32 T 23-10-2018 TAM4_1757 34d63d540200175baa555fba28ce690b 428 Pfam PF01420 Type I restriction modification DNA specificity domain 226 409 8.8E-23 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TAM4_1757 34d63d540200175baa555fba28ce690b 428 Pfam PF01420 Type I restriction modification DNA specificity domain 16 191 4.2E-40 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TAM4_1757 34d63d540200175baa555fba28ce690b 428 Gene3D G3DSA:1.10.287.1120 378 427 6.4E-12 T 23-10-2018 TAM4_960 58acb8f729912cdff9ada5398b9b0456 326 SUPERFAMILY SSF161098 95 305 3.53E-7 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_960 58acb8f729912cdff9ada5398b9b0456 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 320 7.9E-46 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_960 58acb8f729912cdff9ada5398b9b0456 326 Gene3D G3DSA:1.10.3720.10 90 315 8.9E-10 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1530 5a97363400563159191a5563731e70cd 138 Pfam PF01934 Protein of unknown function DUF86 15 130 1.9E-25 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TAM4_1530 5a97363400563159191a5563731e70cd 138 Gene3D G3DSA:1.20.120.580 3 138 6.9E-18 T 23-10-2018 IPR037038 Bsu32300-like superfamily TAM4_1920 705362f3c6102c97b3837800445f1580 153 Gene3D G3DSA:3.40.30.10 2 148 4.1E-44 T 23-10-2018 TAM4_1920 705362f3c6102c97b3837800445f1580 153 SUPERFAMILY SSF52833 7 149 2.7E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_1920 705362f3c6102c97b3837800445f1580 153 PIRSF PIRSF000239 3 147 2.4E-24 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TAM4_1920 705362f3c6102c97b3837800445f1580 153 Pfam PF00578 AhpC/TSA family 7 128 2.0E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 SUPERFAMILY SSF52540 18 260 5.13E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 SUPERFAMILY SSF46785 242 358 2.03E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 Pfam PF01637 ATPase domain predominantly from Archaea 24 221 3.4E-18 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 Pfam PF03008 Archaea bacterial proteins of unknown function 326 425 5.2E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 Gene3D G3DSA:3.40.50.300 16 187 7.6E-26 T 23-10-2018 TAM4_47 9a037e1fd2057f50acfaa4b3b48f241b 479 SUPERFAMILY SSF52980 358 424 6.17E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_1927 3213c0d5b0e924069ab716e5546c39b2 227 Gene3D G3DSA:3.30.420.440 1 227 1.1E-107 T 23-10-2018 TAM4_1927 3213c0d5b0e924069ab716e5546c39b2 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 1.6E-131 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 TAM4_2463 87b4dc9548371290d9a3d6e6f741090f 152 Pfam PF04027 Domain of unknown function (DUF371) 20 150 2.1E-51 T 23-10-2018 IPR007171 Protein of unknown function DUF371 TAM4_2463 87b4dc9548371290d9a3d6e6f741090f 152 Gene3D G3DSA:2.60.120.630 13 152 5.1E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily TAM4_957 faa316d6c659f80c8171d442327d4af1 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 1.9E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_957 faa316d6c659f80c8171d442327d4af1 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 1.9E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_957 faa316d6c659f80c8171d442327d4af1 177 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 1.9E-6 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TAM4_957 faa316d6c659f80c8171d442327d4af1 177 SUPERFAMILY SSF46785 8 68 3.63E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_957 faa316d6c659f80c8171d442327d4af1 177 Gene3D G3DSA:1.10.10.10 14 66 3.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_957 faa316d6c659f80c8171d442327d4af1 177 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 65 6.4E-8 T 23-10-2018 TAM4_957 faa316d6c659f80c8171d442327d4af1 177 SMART SM00344 18 126 9.9E-5 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 Gene3D G3DSA:3.50.50.60 118 440 8.6E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 Gene3D G3DSA:3.50.50.60 237 367 8.6E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 3.0E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 Gene3D G3DSA:3.10.20.440 5 99 2.1E-34 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 2.0E-26 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 2.0E-26 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 2.0E-26 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 2.0E-26 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 2.0E-26 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 2.2E-28 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 3.4E-21 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 3.4E-21 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 3.4E-21 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 3.4E-21 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 3.4E-21 T 23-10-2018 TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 SUPERFAMILY SSF51905 106 430 4.19E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1181 3c835dba360eeaa61daf8c231714ed61 479 SUPERFAMILY SSF54292 17 97 2.49E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TAM4_105 25760efcae6bb3012b3b851c10736133 120 SUPERFAMILY SSF88697 3 109 6.96E-31 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_105 25760efcae6bb3012b3b851c10736133 120 Pfam PF04266 ASCH domain 5 95 1.9E-10 T 23-10-2018 IPR007374 ASCH domain TAM4_105 25760efcae6bb3012b3b851c10736133 120 SMART SM01022 4 92 7.8E-7 T 23-10-2018 IPR007374 ASCH domain TAM4_105 25760efcae6bb3012b3b851c10736133 120 Gene3D G3DSA:2.30.130.30 1 100 3.6E-34 T 23-10-2018 TAM4_833 de7d0a106b81fe6c83cb46451afdee58 198 Pfam PF06510 Protein of unknown function (DUF1102) 39 186 1.9E-55 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 SMART SM00642 325 714 1.2E-98 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 Gene3D G3DSA:2.60.40.10 115 211 1.7E-18 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 122 185 4.1E-11 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 Pfam PF00128 Alpha amylase, catalytic domain 379 684 5.7E-60 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 SUPERFAMILY SSF81296 120 209 1.04E-16 T 23-10-2018 IPR014756 Immunoglobulin E-set TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 SUPERFAMILY SSF51445 303 720 6.93E-98 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 SUPERFAMILY SSF51011 725 785 4.66E-5 T 23-10-2018 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 730 770 7.1E-5 T 23-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TAM4_1607 1c4ef38ed28dd60db3f04098bf60b7db 792 Gene3D G3DSA:3.20.20.80 311 716 9.8E-115 T 23-10-2018 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.7E-10 T 23-10-2018 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 8.7E-10 T 23-10-2018 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 8.7E-10 T 23-10-2018 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 SUPERFAMILY SSF51905 4 329 4.87E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 Gene3D G3DSA:3.50.50.60 5 340 2.0E-106 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 303 1.2E-74 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 Pfam PF01494 FAD binding domain 5 321 9.2E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 3 395 39.265 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 TAM4_1982 73a8cc883997c6e700bbd62d4261e63e 395 Gene3D G3DSA:3.30.9.10 71 358 2.0E-106 T 23-10-2018 TAM4_260 afa032f2627e529cc30115fed31ad70b 259 PIRSF PIRSF005956 1 259 8.1E-98 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TAM4_260 afa032f2627e529cc30115fed31ad70b 259 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 257 6.2E-108 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TAM4_260 afa032f2627e529cc30115fed31ad70b 259 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 7.0E-68 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TAM4_260 afa032f2627e529cc30115fed31ad70b 259 SUPERFAMILY SSF51366 11 251 4.0E-26 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_260 afa032f2627e529cc30115fed31ad70b 259 Pfam PF03437 BtpA family 5 255 1.6E-106 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TAM4_1396 8dd0d567cff841621f23d95added4113 138 SUPERFAMILY SSF47598 3 47 5.56E-14 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TAM4_1396 8dd0d567cff841621f23d95added4113 138 Gene3D G3DSA:3.30.70.1150 51 138 1.3E-36 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TAM4_1396 8dd0d567cff841621f23d95added4113 138 Gene3D G3DSA:1.10.1220.10 10 50 6.8E-23 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TAM4_1396 8dd0d567cff841621f23d95added4113 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 1.9E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TAM4_1396 8dd0d567cff841621f23d95added4113 138 SUPERFAMILY SSF55021 53 133 3.2E-28 T 23-10-2018 TAM4_1396 8dd0d567cff841621f23d95added4113 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 5.8E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal TAM4_1396 8dd0d567cff841621f23d95added4113 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.61 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 Gene3D G3DSA:2.40.50.140 176 323 6.1E-11 T 23-10-2018 TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 SUPERFAMILY SSF50249 56 176 3.18E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 SUPERFAMILY SSF50249 180 343 8.08E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 Pfam PF08646 Replication factor-A C terminal domain 195 285 1.1E-8 T 23-10-2018 IPR013955 Replication factor A, C-terminal TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 Gene3D G3DSA:2.40.50.140 61 175 2.3E-25 T 23-10-2018 TAM4_1511 263ada741c80240abb57b7b64b9b3134 359 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 7.8E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 1.1E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 Pfam PF01048 Phosphorylase superfamily 3 246 1.3E-54 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 Gene3D G3DSA:3.40.50.1580 1 266 2.2E-100 T 23-10-2018 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 SUPERFAMILY SSF53167 1 264 8.77E-95 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TAM4_95 14290a49a70b639bb3e96711974cf84f 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.593 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 Pfam PF01163 RIO1 family 111 290 7.3E-49 T 23-10-2018 TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 SUPERFAMILY SSF56112 102 272 5.19E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 Gene3D G3DSA:1.10.10.10 5 94 1.8E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 Pfam PF09202 Rio2, N-terminal 13 92 1.1E-22 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 Gene3D G3DSA:1.10.510.10 204 296 3.8E-16 T 23-10-2018 TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 Gene3D G3DSA:3.30.200.20 98 196 2.0E-23 T 23-10-2018 TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 SUPERFAMILY SSF46785 8 94 2.67E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1706 ac36872a13a5f253269386a16adaa90e 310 SMART SM00090 68 298 2.2E-82 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TAM4_2102 79b482ca339d7cca8e7f648e86581256 273 Pfam PF00950 ABC 3 transport family 4 266 8.0E-29 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TAM4_2102 79b482ca339d7cca8e7f648e86581256 273 SUPERFAMILY SSF81345 2 272 1.23E-16 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 186 2.7E-30 T 23-10-2018 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 186 3.9E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 180 3.5E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 175 188 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 Gene3D G3DSA:1.10.150.520 16 87 7.8E-49 T 23-10-2018 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 207 7.4E-52 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 Gene3D G3DSA:3.40.50.1000 3 207 7.8E-49 T 23-10-2018 IPR023214 HAD superfamily TAM4_279 e3e31d9113c2293bfe85c1098eaa2651 214 SUPERFAMILY SSF56784 1 207 6.83E-49 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_666 e2ac4711a4517067c3a9a847434719f2 248 Gene3D G3DSA:3.40.50.300 2 248 1.2E-74 T 23-10-2018 TAM4_666 e2ac4711a4517067c3a9a847434719f2 248 SUPERFAMILY SSF52540 5 243 5.61E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_666 e2ac4711a4517067c3a9a847434719f2 248 Pfam PF06745 KaiC 9 245 2.9E-78 T 23-10-2018 IPR014774 KaiC-like domain TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.744 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 3.9E-106 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 Gene3D G3DSA:3.60.20.10 6 253 2.6E-90 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 Pfam PF00227 Proteasome subunit 33 215 3.8E-64 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 SUPERFAMILY SSF56235 7 242 3.26E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_215 dcd853d01fb9dc9f357d3e3f57dc7fb1 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 SUPERFAMILY SSF52980 9 74 1.04E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 301 28.861 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 SMART SM00530 130 185 4.0E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 SUPERFAMILY SSF47413 126 185 1.34E-11 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 Gene3D G3DSA:1.10.260.40 128 187 2.6E-11 T 23-10-2018 TAM4_2082 c2beb5480e0348794fe4b14d314311f5 317 Pfam PF01381 Helix-turn-helix 131 184 7.0E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_690 3e5f7220169a5277dea2971efa6a21ad 226 Pfam PF12838 4Fe-4S dicluster domain 56 110 1.4E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_690 3e5f7220169a5277dea2971efa6a21ad 226 Gene3D G3DSA:3.30.70.3270 35 166 1.1E-23 T 23-10-2018 TAM4_690 3e5f7220169a5277dea2971efa6a21ad 226 SUPERFAMILY SSF54862 18 114 1.17E-22 T 23-10-2018 TAM4_690 3e5f7220169a5277dea2971efa6a21ad 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 57 68 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_690 3e5f7220169a5277dea2971efa6a21ad 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Gene3D G3DSA:3.40.50.300 34 215 1.6E-109 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Hamap MF_01407 ORC1-type DNA replication protein. 11 393 34.118 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TAM4_1154 e9bd8c45229d21658e89105f77665468 414 PRINTS PR00364 Disease resistance protein signature 143 157 9.2E-6 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 PRINTS PR00364 Disease resistance protein signature 397 413 9.2E-6 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 PRINTS PR00364 Disease resistance protein signature 300 314 9.2E-6 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 PRINTS PR00364 Disease resistance protein signature 59 74 9.2E-6 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 60 195 1.7E-9 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Gene3D G3DSA:1.10.8.60 18 294 1.6E-109 T 23-10-2018 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Gene3D G3DSA:1.10.10.10 303 404 1.2E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1154 e9bd8c45229d21658e89105f77665468 414 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 18 382 8.0E-150 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TAM4_1154 e9bd8c45229d21658e89105f77665468 414 Pfam PF09079 CDC6, C terminal winged helix domain 311 391 2.5E-25 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 SMART SM00382 56 217 9.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1154 e9bd8c45229d21658e89105f77665468 414 SUPERFAMILY SSF46785 296 400 3.08E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1154 e9bd8c45229d21658e89105f77665468 414 SMART SM01074 311 393 1.9E-34 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TAM4_1154 e9bd8c45229d21658e89105f77665468 414 SUPERFAMILY SSF52540 18 290 8.39E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_535 b1abf13d883edc12c19e738e306692a0 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 94 113 2.0E-6 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TAM4_535 b1abf13d883edc12c19e738e306692a0 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 14 31 2.0E-6 T 23-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TAM4_535 b1abf13d883edc12c19e738e306692a0 785 Gene3D G3DSA:3.40.50.880 445 649 2.7E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_535 b1abf13d883edc12c19e738e306692a0 785 SUPERFAMILY SSF51445 4 418 4.59E-62 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_535 b1abf13d883edc12c19e738e306692a0 785 SUPERFAMILY SSF52317 471 628 8.93E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_535 b1abf13d883edc12c19e738e306692a0 785 Pfam PF02449 Beta-galactosidase 25 415 2.9E-76 T 23-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TAM4_583 cd16e70f8c22e397b2c0d7bd25328188 253 Gene3D G3DSA:3.30.470.20 17 232 4.6E-93 T 23-10-2018 TAM4_583 cd16e70f8c22e397b2c0d7bd25328188 253 SUPERFAMILY SSF56059 19 236 7.25E-47 T 23-10-2018 TAM4_583 cd16e70f8c22e397b2c0d7bd25328188 253 Gene3D G3DSA:3.30.1490.20 38 115 4.6E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_583 cd16e70f8c22e397b2c0d7bd25328188 253 Pfam PF13549 ATP-grasp domain 12 234 1.8E-82 T 23-10-2018 TAM4_241 ec3deb345718ec6463405240b77fa19a 104 SUPERFAMILY SSF81593 3 101 3.34E-27 T 23-10-2018 TAM4_241 ec3deb345718ec6463405240b77fa19a 104 SMART SM00748 1 94 1.7E-21 T 23-10-2018 IPR007842 HEPN domain TAM4_241 ec3deb345718ec6463405240b77fa19a 104 Pfam PF05168 HEPN domain 2 100 3.8E-22 T 23-10-2018 IPR007842 HEPN domain TAM4_241 ec3deb345718ec6463405240b77fa19a 104 Gene3D G3DSA:1.20.120.330 1 103 1.8E-25 T 23-10-2018 TAM4_1459 c374ab882e8572b63f90ff827782a87a 161 SMART SM00981 63 150 6.0E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_1459 c374ab882e8572b63f90ff827782a87a 161 Gene3D G3DSA:3.30.2130.30 1 151 1.7E-18 T 23-10-2018 TAM4_1459 c374ab882e8572b63f90ff827782a87a 161 SUPERFAMILY SSF143437 34 147 2.96E-18 T 23-10-2018 TAM4_1459 c374ab882e8572b63f90ff827782a87a 161 Pfam PF02926 THUMP domain 29 148 8.3E-23 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_2115 cb0aa3163015c0e61dfd40e76c72d1a2 142 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 14 73 2.0E-5 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_2115 cb0aa3163015c0e61dfd40e76c72d1a2 142 Gene3D G3DSA:3.10.330.10 1 78 4.1E-26 T 23-10-2018 TAM4_2115 cb0aa3163015c0e61dfd40e76c72d1a2 142 SUPERFAMILY SSF54585 2 78 3.6E-13 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TAM4_2115 cb0aa3163015c0e61dfd40e76c72d1a2 142 SMART SM01072 12 74 4.1E-7 T 23-10-2018 IPR004201 CDC48, domain 2 TAM4_2115 cb0aa3163015c0e61dfd40e76c72d1a2 142 Gene3D G3DSA:2.40.10.360 81 141 2.2E-11 T 23-10-2018 TAM4_707 100bd3734c3852fac52537ae06d3086d 863 Gene3D G3DSA:3.60.40.10 603 858 2.2E-71 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_707 100bd3734c3852fac52537ae06d3086d 863 Pfam PF00481 Protein phosphatase 2C 645 851 1.8E-20 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_707 100bd3734c3852fac52537ae06d3086d 863 SMART SM00332 609 856 3.0E-38 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_707 100bd3734c3852fac52537ae06d3086d 863 SUPERFAMILY SSF81606 618 855 1.31E-63 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_707 100bd3734c3852fac52537ae06d3086d 863 SMART SM00331 610 858 1.8E-45 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TAM4_1491 c43657a692b8fd407b179fe877177632 364 Gene3D G3DSA:1.25.40.10 1 349 8.4E-45 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1491 c43657a692b8fd407b179fe877177632 364 SUPERFAMILY SSF48452 34 142 7.05E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 Pfam PF03008 Archaea bacterial proteins of unknown function 300 396 8.2E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 SUPERFAMILY SSF52540 3 232 5.17E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 SUPERFAMILY SSF46785 222 344 3.34E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 SUPERFAMILY SSF52980 330 447 2.86E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 Gene3D G3DSA:3.40.50.300 1 73 2.2E-9 T 23-10-2018 TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 Gene3D G3DSA:3.40.50.300 74 160 2.3E-15 T 23-10-2018 TAM4_439 ee90d1006c4454e62659371afe3d9f29 453 Pfam PF01637 ATPase domain predominantly from Archaea 4 195 7.5E-25 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_567 8a35e79ca9bb84d72058ae3addee1bd3 280 SUPERFAMILY SSF52096 13 240 1.97E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TAM4_567 8a35e79ca9bb84d72058ae3addee1bd3 280 Pfam PF01972 Serine dehydrogenase proteinase 1 276 3.1E-153 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TAM4_567 8a35e79ca9bb84d72058ae3addee1bd3 280 Gene3D G3DSA:3.90.226.10 61 267 2.5E-24 T 23-10-2018 TAM4_1193 82933a6cc86916b94551b0057d1dd657 169 Gene3D G3DSA:3.30.70.20 36 106 3.4E-12 T 23-10-2018 TAM4_1193 82933a6cc86916b94551b0057d1dd657 169 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1193 82933a6cc86916b94551b0057d1dd657 169 Pfam PF00037 4Fe-4S binding domain 67 88 1.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_1193 82933a6cc86916b94551b0057d1dd657 169 SUPERFAMILY SSF54862 4 137 2.44E-19 T 23-10-2018 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 Gene3D G3DSA:3.30.750.80 72 178 1.7E-36 T 23-10-2018 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 Gene3D G3DSA:2.30.130.10 1 70 1.9E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 SMART SM00359 2 87 2.9E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 Gene3D G3DSA:3.40.50.150 179 396 1.3E-70 T 23-10-2018 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 Pfam PF01472 PUA domain 3 63 8.1E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 SUPERFAMILY SSF53335 78 390 5.67E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 SUPERFAMILY SSF88697 1 65 2.17E-17 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_852 551c71eb10e36f8b7bd9baf4bff9795c 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 343 1.1E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TAM4_2035 42798c9639f42e8620ae9ff2a47920b7 124 Pfam PF05168 HEPN domain 4 118 1.3E-31 T 23-10-2018 IPR007842 HEPN domain TAM4_2035 42798c9639f42e8620ae9ff2a47920b7 124 SMART SM00748 7 113 4.3E-18 T 23-10-2018 IPR007842 HEPN domain TAM4_2035 42798c9639f42e8620ae9ff2a47920b7 124 Gene3D G3DSA:1.20.120.330 2 122 2.4E-33 T 23-10-2018 TAM4_2035 42798c9639f42e8620ae9ff2a47920b7 124 SUPERFAMILY SSF81593 5 120 3.3E-29 T 23-10-2018 TAM4_687 6b1708a3d82600c164f7e03c8bf29e0d 389 Gene3D G3DSA:3.40.50.1980 41 187 3.7E-53 T 23-10-2018 TAM4_687 6b1708a3d82600c164f7e03c8bf29e0d 389 Gene3D G3DSA:3.40.50.1980 188 385 3.6E-76 T 23-10-2018 TAM4_687 6b1708a3d82600c164f7e03c8bf29e0d 389 SUPERFAMILY SSF53807 51 366 3.68E-57 T 23-10-2018 TAM4_687 6b1708a3d82600c164f7e03c8bf29e0d 389 Pfam PF01497 Periplasmic binding protein 67 310 3.5E-22 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TAM4_3 5f658e29415c39a78570d4a301162bd2 223 Pfam PF04172 LrgB-like family 9 221 3.3E-71 T 23-10-2018 IPR007300 CidB/LrgB family TAM4_3 5f658e29415c39a78570d4a301162bd2 223 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 222 6.6E-80 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 5.3E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Gene3D G3DSA:3.40.50.20 1 85 9.6E-30 T 23-10-2018 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Pfam PF06973 Domain of unknown function (DUF1297) 150 331 3.9E-72 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Gene3D G3DSA:3.30.470.20 87 330 4.1E-97 T 23-10-2018 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Gene3D G3DSA:3.30.1490.20 114 174 4.1E-97 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_1003 f43a8389b46528341db91d476c57e437 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 48.989 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_1003 f43a8389b46528341db91d476c57e437 331 SUPERFAMILY SSF52440 1 97 1.25E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TAM4_1003 f43a8389b46528341db91d476c57e437 331 PIRSF PIRSF004602 1 331 1.6E-131 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TAM4_1003 f43a8389b46528341db91d476c57e437 331 SUPERFAMILY SSF56059 101 331 3.54E-78 T 23-10-2018 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 5.6E-23 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 1.0E-20 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 9.4E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 Gene3D G3DSA:3.30.1280.10 1 80 2.7E-27 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 19.711 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TAM4_641 eb7c720c52db72abf2a8db49729ab1f7 80 SUPERFAMILY SSF82697 3 78 2.27E-23 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TAM4_571 34c42d1f0b12ca77052b29c5d27d90ae 361 Gene3D G3DSA:3.20.20.70 24 286 1.6E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_571 34c42d1f0b12ca77052b29c5d27d90ae 361 Pfam PF13394 4Fe-4S single cluster domain 31 121 4.7E-6 T 23-10-2018 TAM4_571 34c42d1f0b12ca77052b29c5d27d90ae 361 Pfam PF04055 Radical SAM superfamily 33 186 2.7E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_571 34c42d1f0b12ca77052b29c5d27d90ae 361 SUPERFAMILY SSF102114 27 206 6.41E-25 T 23-10-2018 TAM4_191 f3132eea4acaa805a172bf87061c44d5 234 Gene3D G3DSA:3.30.460.10 21 95 1.0E-6 T 23-10-2018 TAM4_191 f3132eea4acaa805a172bf87061c44d5 234 Pfam PF01909 Nucleotidyltransferase domain 45 116 2.3E-6 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_191 f3132eea4acaa805a172bf87061c44d5 234 SUPERFAMILY SSF81301 20 73 2.36E-8 T 23-10-2018 TAM4_191 f3132eea4acaa805a172bf87061c44d5 234 PIRSF PIRSF005928 10 232 9.8E-102 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 120 170 7.0E-17 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 63 190 2.4E-22 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 150 171 - T 23-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Pfam PF00374 Nickel-dependent hydrogenase 247 316 7.2E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 324 491 2.1E-42 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 500 569 6.5E-16 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 SUPERFAMILY SSF56762 219 569 5.76E-115 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 SUPERFAMILY SSF143243 39 223 2.35E-39 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Gene3D G3DSA:3.30.460.80 18 169 6.1E-15 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1173 220449f9e0d4c57376d02a90f42d2e10 599 Gene3D G3DSA:1.10.645.20 209 569 1.7E-127 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 SUPERFAMILY SSF101821 68 176 2.44E-27 T 23-10-2018 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 Gene3D G3DSA:2.40.30.40 68 160 1.8E-131 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 SUPERFAMILY SSF53187 4 338 2.18E-63 T 23-10-2018 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 PIRSF PIRSF001123 1 344 1.8E-102 T 23-10-2018 IPR008007 Peptidase M42 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 329 2.5E-96 T 23-10-2018 IPR008007 Peptidase M42 TAM4_550 a22df0cef753f3449a5af8bf449bac18 345 Gene3D G3DSA:3.40.630.10 7 332 1.8E-131 T 23-10-2018 TAM4_1474 e478dce4dc39cd0f0f815f65e851e5ec 268 SUPERFAMILY SSF51658 13 238 5.5E-28 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TAM4_1474 e478dce4dc39cd0f0f815f65e851e5ec 268 Gene3D G3DSA:3.20.20.150 1 256 8.6E-27 T 23-10-2018 TAM4_1474 e478dce4dc39cd0f0f815f65e851e5ec 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 4.6E-16 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 547 564 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 SUPERFAMILY SSF51569 3 301 9.34E-87 T 23-10-2018 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 Pfam PF02436 Conserved carboxylase domain 292 473 9.4E-56 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 Pfam PF00682 HMGL-like 3 234 1.0E-41 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 Gene3D G3DSA:3.20.20.70 2 452 7.3E-165 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 Gene3D G3DSA:2.40.50.100 518 591 2.6E-29 T 23-10-2018 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 SUPERFAMILY SSF51230 512 590 8.64E-26 T 23-10-2018 IPR011053 Single hybrid motif TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 SUPERFAMILY SSF89000 297 453 1.02E-54 T 23-10-2018 TAM4_1788 36f71289e146a0f947e6e112d99f9a27 591 Pfam PF00364 Biotin-requiring enzyme 524 590 3.3E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TAM4_1088 962b82a8bc2c9b4714da3575d2bbc424 379 Pfam PF13579 Glycosyl transferase 4-like domain 15 169 1.9E-22 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TAM4_1088 962b82a8bc2c9b4714da3575d2bbc424 379 Gene3D G3DSA:3.40.50.2000 1 181 1.1E-25 T 23-10-2018 TAM4_1088 962b82a8bc2c9b4714da3575d2bbc424 379 Pfam PF00534 Glycosyl transferases group 1 188 305 5.7E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TAM4_1088 962b82a8bc2c9b4714da3575d2bbc424 379 SUPERFAMILY SSF53756 2 349 6.85E-63 T 23-10-2018 TAM4_1088 962b82a8bc2c9b4714da3575d2bbc424 379 Gene3D G3DSA:3.40.50.2000 182 353 4.1E-32 T 23-10-2018 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 262 6.4E-92 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 1.9E-109 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.788 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 SUPERFAMILY SSF51621 4 262 1.53E-103 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 PIRSF PIRSF000388 1 265 6.6E-106 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TAM4_1533 0d4d094b778b35ad1f4c873c4c3e342f 289 Gene3D G3DSA:3.20.20.60 2 273 3.8E-112 T 23-10-2018 TAM4_1405 4ac427d9c6c233a9d41becb6fef66991 303 Gene3D G3DSA:3.20.20.70 52 285 5.8E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1405 4ac427d9c6c233a9d41becb6fef66991 303 SUPERFAMILY SSF102114 61 262 6.02E-30 T 23-10-2018 TAM4_1405 4ac427d9c6c233a9d41becb6fef66991 303 SMART SM00729 57 254 2.9E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1405 4ac427d9c6c233a9d41becb6fef66991 303 Pfam PF04055 Radical SAM superfamily 62 211 4.5E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_465 4d816016fc7a3fd3917f93587111e372 397 Gene3D G3DSA:1.20.1530.20 18 389 3.2E-43 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_465 4d816016fc7a3fd3917f93587111e372 397 Pfam PF00999 Sodium/hydrogen exchanger family 25 377 1.5E-31 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_2135 b1497a41316b608526f88c4a5e827c6e 97 Gene3D G3DSA:1.20.120.460 3 97 1.4E-35 T 23-10-2018 IPR038317 Pf1176-like superfamily TAM4_2135 b1497a41316b608526f88c4a5e827c6e 97 Pfam PF11505 Protein of unknown function (DUF3216) 7 96 5.4E-39 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 TAM4_722 9e01bd492b25d44e64ba47a4c5444f52 419 Pfam PF04055 Radical SAM superfamily 123 287 8.7E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_722 9e01bd492b25d44e64ba47a4c5444f52 419 Gene3D G3DSA:3.20.20.70 111 355 4.7E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_722 9e01bd492b25d44e64ba47a4c5444f52 419 SUPERFAMILY SSF102114 109 329 1.03E-39 T 23-10-2018 TAM4_722 9e01bd492b25d44e64ba47a4c5444f52 419 SMART SM00729 115 332 4.9E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_2014 6cfc1d57320ef21af2f08856a54c1a28 249 Gene3D G3DSA:3.60.15.10 1 249 1.8E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2014 6cfc1d57320ef21af2f08856a54c1a28 249 SUPERFAMILY SSF56281 1 247 1.16E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2014 6cfc1d57320ef21af2f08856a54c1a28 249 SMART SM00849 37 215 1.4E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2014 6cfc1d57320ef21af2f08856a54c1a28 249 Pfam PF12706 Beta-lactamase superfamily domain 64 216 1.6E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 Gene3D G3DSA:3.40.630.10 7 211 2.2E-42 T 23-10-2018 TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 Gene3D G3DSA:3.40.630.10 318 420 9.2E-14 T 23-10-2018 TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 Gene3D G3DSA:3.30.70.360 212 317 3.1E-19 T 23-10-2018 TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 SUPERFAMILY SSF55031 208 320 1.17E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 Pfam PF07687 Peptidase dimerisation domain 204 315 5.0E-22 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 SUPERFAMILY SSF53187 4 419 5.28E-63 T 23-10-2018 TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 Pfam PF01546 Peptidase family M20/M25/M40 95 418 2.2E-39 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TAM4_437 8bba0fc0d5c52054f5cd8cb562d8ab50 420 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 413 8.6E-81 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 544 2.0E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 261 7.6E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 Gene3D G3DSA:1.10.3720.10 293 549 5.2E-45 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 Gene3D G3DSA:1.10.3720.10 4 277 1.4E-64 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 SUPERFAMILY SSF161098 290 546 1.59E-47 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_778 fb79183a259e75e7650c73899bfc4a7d 552 SUPERFAMILY SSF161098 9 273 4.02E-52 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_617 c188217a8ad2d0307924857dc93f651c 137 Gene3D G3DSA:3.40.50.1010 1 131 6.2E-31 T 23-10-2018 TAM4_617 c188217a8ad2d0307924857dc93f651c 137 SUPERFAMILY SSF88723 2 135 6.73E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_617 c188217a8ad2d0307924857dc93f651c 137 Pfam PF01850 PIN domain 2 128 5.5E-14 T 23-10-2018 IPR002716 PIN domain TAM4_930 f7f1ff6055acdc27d4b8b19507a711dd 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 3.9E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 SUPERFAMILY SSF55920 141 358 4.32E-41 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 1.8E-13 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 Gene3D G3DSA:3.90.230.10 143 358 9.5E-39 T 23-10-2018 TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 SUPERFAMILY SSF53092 6 141 1.08E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 Gene3D G3DSA:3.40.350.10 7 142 5.4E-21 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_2094 f3168afdb7181ad9b9a4aaa96759adff 358 Pfam PF00557 Metallopeptidase family M24 149 350 1.7E-27 T 23-10-2018 IPR000994 Peptidase M24 TAM4_629 6fb6056603ac0653d356eafaedd045ae 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 8.4E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_629 6fb6056603ac0653d356eafaedd045ae 91 Gene3D G3DSA:2.10.260.10 4 44 1.0E-9 T 23-10-2018 TAM4_629 6fb6056603ac0653d356eafaedd045ae 91 SUPERFAMILY SSF89447 4 46 3.53E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_629 6fb6056603ac0653d356eafaedd045ae 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 49 4.2E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_629 6fb6056603ac0653d356eafaedd045ae 91 SMART SM00966 6 51 4.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_899 2e62134c1b0d6bd50d313a483f7d643e 73 Pfam PF02381 MraZ protein, putative antitoxin-like 8 44 1.8E-5 T 23-10-2018 IPR020603 MraZ domain TAM4_899 2e62134c1b0d6bd50d313a483f7d643e 73 SUPERFAMILY SSF89447 4 63 1.03E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_899 2e62134c1b0d6bd50d313a483f7d643e 73 SMART SM00966 7 48 1.4E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_899 2e62134c1b0d6bd50d313a483f7d643e 73 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 42 1.2E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_614 ccbef8e935fca0acd139f61bdc443f1e 269 SUPERFAMILY SSF52540 5 230 1.62E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_614 ccbef8e935fca0acd139f61bdc443f1e 269 SMART SM00382 29 213 1.3E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_614 ccbef8e935fca0acd139f61bdc443f1e 269 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_614 ccbef8e935fca0acd139f61bdc443f1e 269 Pfam PF00005 ABC transporter 20 166 1.1E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_614 ccbef8e935fca0acd139f61bdc443f1e 269 Gene3D G3DSA:3.40.50.300 4 261 5.0E-72 T 23-10-2018 TAM4_1556 2e5bab7b899aafc674f6995f2c9891ab 142 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 1 141 2.0E-63 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TAM4_1556 2e5bab7b899aafc674f6995f2c9891ab 142 Hamap MF_00498 UPF0179 protein . 1 139 23.805 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TAM4_1556 2e5bab7b899aafc674f6995f2c9891ab 142 Pfam PF03684 Uncharacterised protein family (UPF0179) 3 137 5.7E-43 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TAM4_1556 2e5bab7b899aafc674f6995f2c9891ab 142 PIRSF PIRSF006595 1 142 1.2E-50 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TAM4_1789 34c62595e18863011f31bd89f473e666 76 SUPERFAMILY SSF50182 5 74 1.96E-16 T 23-10-2018 IPR010920 LSM domain superfamily TAM4_1789 34c62595e18863011f31bd89f473e666 76 Gene3D G3DSA:2.30.30.100 1 74 2.0E-21 T 23-10-2018 TAM4_1789 34c62595e18863011f31bd89f473e666 76 SMART SM00651 7 72 3.1E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TAM4_1789 34c62595e18863011f31bd89f473e666 76 Pfam PF01423 LSM domain 9 72 2.4E-16 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TAM4_1789 34c62595e18863011f31bd89f473e666 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 24.446 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 564 1.3E-218 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 SUPERFAMILY SSF52954 461 566 9.82E-34 T 23-10-2018 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Gene3D G3DSA:1.10.30.30 362 425 6.9E-142 T 23-10-2018 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 SUPERFAMILY SSF55681 6 477 1.54E-117 T 23-10-2018 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Gene3D G3DSA:3.30.930.10 13 457 6.9E-142 T 23-10-2018 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Gene3D G3DSA:1.20.1430.20 83 146 6.9E-142 T 23-10-2018 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 340 1.4E-10 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 5 567 46.94 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Pfam PF03129 Anticodon binding domain 474 564 1.7E-24 T 23-10-2018 IPR004154 Anticodon-binding TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 141 153 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 209 219 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 512 531 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 192 209 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 434 446 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 160 177 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TAM4_1790 fbad5881686efd5c8800c058cd4ac8b4 569 Gene3D G3DSA:3.40.50.800 472 569 1.0E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 SUPERFAMILY SSF53092 2 131 1.13E-15 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 Gene3D G3DSA:3.40.350.10 1 131 1.2E-32 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 SUPERFAMILY SSF55920 132 358 6.93E-74 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 Gene3D G3DSA:3.90.230.10 133 358 1.9E-80 T 23-10-2018 TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 133 4.0E-19 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TAM4_273 88b7d884ff0253a32de8e299d39bdcb0 358 Pfam PF00557 Metallopeptidase family M24 141 340 9.9E-68 T 23-10-2018 IPR000994 Peptidase M24 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 Gene3D G3DSA:3.40.50.300 2 234 2.2E-72 T 23-10-2018 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 280 343 3.4E-19 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 SMART SM00382 25 330 8.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 Gene3D G3DSA:2.40.50.100 268 339 2.1E-29 T 23-10-2018 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 Pfam PF00005 ABC transporter 16 159 1.0E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 Pfam PF03459 TOBE domain 281 343 2.9E-17 T 23-10-2018 IPR005116 Transport-associated OB, type 1 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 SUPERFAMILY SSF52540 1 237 8.87E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 Gene3D G3DSA:2.40.50.140 245 343 2.1E-29 T 23-10-2018 TAM4_1544 afef8075aabbbe34599b46c24c98e573 344 SUPERFAMILY SSF50331 235 344 1.23E-23 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 Gene3D G3DSA:2.80.10.50 29 166 2.6E-8 T 23-10-2018 TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 Gene3D G3DSA:2.80.10.50 167 294 2.5E-5 T 23-10-2018 TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 91 130 5.1E-5 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 143 176 0.001 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 244 283 0.0045 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 SUPERFAMILY SSF50998 28 316 1.8E-21 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_1427 94f501168cf8b1a4ba04eb9c2f23cd34 481 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 100 130 0.002 T 23-10-2018 IPR013431 Delta-60 repeat TAM4_1418 a70844ca84c037599dd4525b64922e24 134 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 109 3.0E-21 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TAM4_1418 a70844ca84c037599dd4525b64922e24 134 Hamap MF_00585 UPF0216 protein . 4 134 27.085 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TAM4_1418 a70844ca84c037599dd4525b64922e24 134 Pfam PF01886 Protein of unknown function DUF61 6 131 1.0E-34 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TAM4_1418 a70844ca84c037599dd4525b64922e24 134 PIRSF PIRSF005264 1 134 4.7E-43 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 SUPERFAMILY SSF55287 2 70 2.35E-26 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 1 70 20.395 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 Gene3D G3DSA:3.90.940.20 1 72 1.3E-32 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 4 69 7.0E-18 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 2 69 1.5E-30 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_1695 ce5073ba391d924c6b119a4a68774460 72 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 2 15 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 8.7E-100 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 Gene3D G3DSA:3.40.50.10490 7 201 9.2E-72 T 23-10-2018 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 SUPERFAMILY SSF52313 3 192 2.75E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.577 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 Pfam PF00318 Ribosomal protein S2 110 174 3.1E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 Pfam PF00318 Ribosomal protein S2 12 103 9.6E-11 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_55 481f56dbee305ca45e7c5cb3155d03c9 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 7.7E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_890 34933274a31c4d1c77b97e7679d93612 339 Pfam PF00466 Ribosomal protein L10 5 105 3.3E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TAM4_890 34933274a31c4d1c77b97e7679d93612 339 SUPERFAMILY SSF160369 5 141 8.76E-26 T 23-10-2018 TAM4_890 34933274a31c4d1c77b97e7679d93612 339 Gene3D G3DSA:3.90.105.20 107 186 1.0E-74 T 23-10-2018 TAM4_890 34933274a31c4d1c77b97e7679d93612 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 36.577 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea TAM4_890 34933274a31c4d1c77b97e7679d93612 339 Gene3D G3DSA:3.30.70.1730 15 210 1.0E-74 T 23-10-2018 TAM4_890 34933274a31c4d1c77b97e7679d93612 339 Pfam PF00428 60s Acidic ribosomal protein 232 338 1.1E-6 T 23-10-2018 TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 SUPERFAMILY SSF47240 307 449 8.85E-12 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 SUPERFAMILY SSF47240 101 239 3.49E-11 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 Pfam PF09968 Uncharacterized protein domain (DUF2202) 100 260 1.7E-65 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 Pfam PF09968 Uncharacterized protein domain (DUF2202) 308 467 1.4E-68 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 Gene3D G3DSA:1.20.1260.10 95 268 1.6E-73 T 23-10-2018 IPR012347 Ferritin-like TAM4_1616 2fd693a09bb9ac1cfdaa41c5146d9033 480 Gene3D G3DSA:1.20.1260.10 303 476 7.2E-74 T 23-10-2018 IPR012347 Ferritin-like TAM4_1845 9c8746b44c7bf126202ffac31954a4d6 291 Pfam PF01875 Memo-like protein 5 288 1.8E-71 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TAM4_1845 9c8746b44c7bf126202ffac31954a4d6 291 SUPERFAMILY SSF53213 55 272 1.28E-9 T 23-10-2018 TAM4_1845 9c8746b44c7bf126202ffac31954a4d6 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 288 1.2E-88 T 23-10-2018 TAM4_1845 9c8746b44c7bf126202ffac31954a4d6 291 Gene3D G3DSA:3.40.830.10 1 291 8.1E-68 T 23-10-2018 TAM4_1845 9c8746b44c7bf126202ffac31954a4d6 291 Hamap MF_00055 MEMO1 family protein . 1 290 60.253 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TAM4_625 caa59d920800a9c0a0cd9341e22bc55d 207 SUPERFAMILY SSF75689 4 38 1.44E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_625 caa59d920800a9c0a0cd9341e22bc55d 207 Pfam PF01873 Domain found in IF2B/IF5 2 34 5.2E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_625 caa59d920800a9c0a0cd9341e22bc55d 207 PIRSF PIRSF015877 1 199 8.4E-66 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing TAM4_1234 96bec0816b0a8535c501978966cface5 104 Gene3D G3DSA:3.30.70.120 1 103 4.2E-35 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TAM4_1234 96bec0816b0a8535c501978966cface5 104 SUPERFAMILY SSF54913 3 100 7.04E-32 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TAM4_1234 96bec0816b0a8535c501978966cface5 104 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 4.1E-30 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TAM4_1624 afe08f5553b491157a21753abd4d6c7e 281 SMART SM01133 23 251 2.7E-44 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1624 afe08f5553b491157a21753abd4d6c7e 281 SUPERFAMILY SSF51569 8 266 6.23E-69 T 23-10-2018 TAM4_1624 afe08f5553b491157a21753abd4d6c7e 281 PIRSF PIRSF038992 4 280 1.2E-91 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_1624 afe08f5553b491157a21753abd4d6c7e 281 Gene3D G3DSA:3.20.20.70 3 279 4.9E-84 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1624 afe08f5553b491157a21753abd4d6c7e 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 1.8E-34 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 SUPERFAMILY SSF54768 62 125 4.5E-18 T 23-10-2018 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 7.3E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 Gene3D G3DSA:3.30.160.770 12 122 3.5E-37 T 23-10-2018 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 1.1E-20 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 SUPERFAMILY SSF54211 138 210 4.55E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_54 a2a8ffeba918cee186470af48c032c78 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 47.853 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_54 a2a8ffeba918cee186470af48c032c78 235 Gene3D G3DSA:3.30.230.10 123 214 1.7E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_54 a2a8ffeba918cee186470af48c032c78 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TAM4_54 a2a8ffeba918cee186470af48c032c78 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 6.4E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TAM4_1943 39a375296dc5d333f5415f43f20e2310 180 SUPERFAMILY SSF53335 35 122 1.3E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1943 39a375296dc5d333f5415f43f20e2310 180 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 88 9.7E-6 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TAM4_1943 39a375296dc5d333f5415f43f20e2310 180 Gene3D G3DSA:3.40.50.150 1 169 3.0E-19 T 23-10-2018 TAM4_1782 831851d9d89203f5872b6872a0be0554 359 SUPERFAMILY SSF52540 29 223 6.26E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1782 831851d9d89203f5872b6872a0be0554 359 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 35 215 6.7E-36 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TAM4_1782 831851d9d89203f5872b6872a0be0554 359 Gene3D G3DSA:3.40.50.300 14 219 1.4E-22 T 23-10-2018 TAM4_2473 c944035c022dc833e6defc6d9b18b415 248 Pfam PF05971 Protein of unknown function (DUF890) 20 163 6.0E-10 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 TAM4_2473 c944035c022dc833e6defc6d9b18b415 248 SUPERFAMILY SSF53335 14 229 2.92E-24 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_2473 c944035c022dc833e6defc6d9b18b415 248 Gene3D G3DSA:3.40.50.150 66 248 4.0E-43 T 23-10-2018 TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 PIRSF PIRSF006443 1 171 9.8E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 Pfam PF00994 Probable molybdopterin binding domain 17 160 1.0E-35 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 SMART SM00852 17 165 1.8E-28 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 3.9E-35 T 23-10-2018 IPR001453 MoaB/Mog domain TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 Gene3D G3DSA:3.40.980.10 12 170 1.2E-46 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_1663 9218f1d3873a2996a7015f80d0b02025 171 SUPERFAMILY SSF53218 12 168 6.28E-43 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 Gene3D G3DSA:3.90.660.50 83 359 3.1E-144 T 23-10-2018 TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 6.7E-6 T 23-10-2018 TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 6.7E-6 T 23-10-2018 TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 Pfam PF01593 Flavin containing amine oxidoreductase 10 240 1.4E-15 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 SUPERFAMILY SSF51905 1 392 3.08E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1446 1d97b4ba62ec232ddd8bf2fc3650e8a2 420 Gene3D G3DSA:3.50.50.60 4 403 3.1E-144 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_2050 b86225d806638282ad21d63d2c1c7450 210 Pfam PF00005 ABC transporter 20 144 2.7E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2050 b86225d806638282ad21d63d2c1c7450 210 Gene3D G3DSA:3.40.50.300 2 207 1.3E-54 T 23-10-2018 TAM4_2050 b86225d806638282ad21d63d2c1c7450 210 SUPERFAMILY SSF52540 6 191 1.03E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2050 b86225d806638282ad21d63d2c1c7450 210 SMART SM00382 29 209 4.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 Pfam PF14697 4Fe-4S dicluster domain 64 118 1.4E-12 T 23-10-2018 TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 Gene3D G3DSA:3.30.70.20 69 116 2.9E-10 T 23-10-2018 TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 SUPERFAMILY SSF54862 55 120 5.44E-18 T 23-10-2018 TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 266 1.3E-22 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 SUPERFAMILY SSF52540 2 294 7.11E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_847 4b92bb364267f53dd27c75f3203d2030 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1779 1d3374bc2149dec9499076191ad4e0fd 215 Pfam PF00156 Phosphoribosyl transferase domain 13 152 1.2E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TAM4_1779 1d3374bc2149dec9499076191ad4e0fd 215 Gene3D G3DSA:3.40.50.2020 5 182 7.3E-43 T 23-10-2018 TAM4_1779 1d3374bc2149dec9499076191ad4e0fd 215 SUPERFAMILY SSF53271 8 161 7.21E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_1301 91c86e87d3092c661a470369bcaa88f8 245 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 9 238 3.9E-73 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TAM4_1301 91c86e87d3092c661a470369bcaa88f8 245 PIRSF PIRSF019322 5 245 4.4E-92 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 630 7.6E-33 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1158 6.7E-82 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:3.40.50.300 1014 1185 8.2E-60 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:1.20.1060.20 507 660 3.6E-45 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:1.20.5.340 379 501 3.6E-5 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:1.20.5.340 774 872 6.6E-9 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 SUPERFAMILY SSF52540 952 1168 3.94E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1165 1.5E-236 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 SUPERFAMILY SSF75553 487 677 8.11E-50 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1165 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 PIRSF PIRSF005719 1 1172 1.1E-280 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 SUPERFAMILY SSF57997 668 932 3.27E-6 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 SUPERFAMILY SSF52540 3 297 9.15E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:3.40.50.300 2 233 2.2E-61 T 23-10-2018 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1167 21.506 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 SMART SM00968 520 632 1.6E-43 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TAM4_1857 ff4d8dabd57c3a48180e6cec650216ad 1192 Gene3D G3DSA:3.30.70.1620 581 658 3.6E-45 T 23-10-2018 TAM4_1140 50c628e6e280db5469357a59f4831987 310 SUPERFAMILY SSF161098 69 288 8.99E-9 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1140 50c628e6e280db5469357a59f4831987 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 304 2.2E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_871 f0a9970792d9c906f7b573a4d3f3f4b7 314 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 49 137 2.7E-8 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TAM4_871 f0a9970792d9c906f7b573a4d3f3f4b7 314 Gene3D G3DSA:3.90.1570.30 29 172 1.5E-5 T 23-10-2018 TAM4_234 119731fd72ab4dc68714bf47a5903061 216 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 7 207 2.6E-53 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TAM4_234 119731fd72ab4dc68714bf47a5903061 216 Gene3D G3DSA:3.40.50.11570 1 212 1.1E-58 T 23-10-2018 TAM4_682 8fa213e5d87d5e724c88b559858d086a 274 Pfam PF05763 Protein of unknown function (DUF835) 149 246 8.6E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1134 196951eb3f57b86f2c867459554e7e06 276 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 18 143 5.0E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1134 196951eb3f57b86f2c867459554e7e06 276 SUPERFAMILY SSF56770 5 157 2.75E-46 T 23-10-2018 TAM4_1134 196951eb3f57b86f2c867459554e7e06 276 Gene3D G3DSA:3.40.50.12280 2 167 1.8E-44 T 23-10-2018 TAM4_1623 53852991976a3ece79b041d260878e96 159 PIRSF PIRSF018660 7 159 1.1E-18 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C TAM4_1623 53852991976a3ece79b041d260878e96 159 Pfam PF05377 Flagella accessory protein C (FlaC) 50 103 2.6E-21 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C TAM4_1623 53852991976a3ece79b041d260878e96 159 Gene3D G3DSA:1.20.5.340 10 143 8.9E-7 T 23-10-2018 TAM4_562 2437393c9a569d69678d46a443fc36f7 109 Pfam PF01922 SRP19 protein 5 92 1.9E-11 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_562 2437393c9a569d69678d46a443fc36f7 109 SUPERFAMILY SSF69695 2 100 7.46E-20 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_562 2437393c9a569d69678d46a443fc36f7 109 Gene3D G3DSA:3.30.56.30 1 105 2.4E-31 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TAM4_1248 55bb39a1c98d464450f31913e61a48be 356 Gene3D G3DSA:1.10.1580.10 170 251 1.8E-13 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily TAM4_1248 55bb39a1c98d464450f31913e61a48be 356 Pfam PF01926 50S ribosome-binding GTPase 107 162 1.0E-12 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_1248 55bb39a1c98d464450f31913e61a48be 356 SUPERFAMILY SSF52540 4 168 4.06E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1248 55bb39a1c98d464450f31913e61a48be 356 Gene3D G3DSA:3.40.50.300 5 162 6.1E-45 T 23-10-2018 TAM4_1603 30595f6a9d8a9b512d878fb82b028c46 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.701 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1603 30595f6a9d8a9b512d878fb82b028c46 51 SUPERFAMILY SSF48662 4 50 1.15E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TAM4_1603 30595f6a9d8a9b512d878fb82b028c46 51 Gene3D G3DSA:1.10.1620.10 2 51 5.2E-20 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TAM4_1603 30595f6a9d8a9b512d878fb82b028c46 51 Pfam PF00832 Ribosomal L39 protein 9 50 7.2E-23 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1603 30595f6a9d8a9b512d878fb82b028c46 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 4.6E-49 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 Gene3D G3DSA:3.30.190.20 13 213 5.5E-78 T 23-10-2018 TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.223 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 Gene3D G3DSA:3.40.50.790 59 150 5.5E-78 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 SUPERFAMILY SSF56808 5 214 6.28E-66 T 23-10-2018 IPR023674 Ribosomal protein L1-like TAM4_949 9bbcae540693c22aec7fb2ff4fec73c4 216 PIRSF PIRSF002155 2 216 1.0E-67 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 SUPERFAMILY SSF52317 2 195 3.4E-48 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 195 9.3E-62 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 PIRSF PIRSF000495 1 196 7.2E-58 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 196 34.127 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 Gene3D G3DSA:3.40.50.880 1 196 4.7E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1776 b21e193fb4b4dccd83226a8dae855e53 196 Pfam PF00117 Glutamine amidotransferase class-I 34 185 9.9E-19 T 23-10-2018 IPR017926 Glutamine amidotransferase TAM4_2192 6e139d87ebf7ddc261dfb559bc93b998 425 Gene3D G3DSA:3.40.1710.10 42 202 8.7E-44 T 23-10-2018 TAM4_2192 6e139d87ebf7ddc261dfb559bc93b998 425 Pfam PF12698 ABC-2 family transporter protein 19 402 1.6E-36 T 23-10-2018 TAM4_733 da8938517b28317b7460a279183f0660 140 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 11 138 1.5E-35 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_733 da8938517b28317b7460a279183f0660 140 Pfam PF02996 Prefoldin subunit 21 138 8.2E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like TAM4_733 da8938517b28317b7460a279183f0660 140 SUPERFAMILY SSF46579 10 139 2.01E-29 T 23-10-2018 TAM4_733 da8938517b28317b7460a279183f0660 140 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 6 140 15.321 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_733 da8938517b28317b7460a279183f0660 140 Gene3D G3DSA:1.10.287.370 3 140 6.9E-41 T 23-10-2018 IPR009053 Prefoldin TAM4_1849 343acc00428299cc721d0e8b35856b1f 315 Gene3D G3DSA:2.20.28.30 1 36 7.2E-7 T 23-10-2018 TAM4_1849 343acc00428299cc721d0e8b35856b1f 315 Pfam PF13248 zinc-ribbon domain 2 28 8.3E-8 T 23-10-2018 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Pfam PF00009 Elongation factor Tu GTP binding domain 9 215 2.1E-32 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 SUPERFAMILY SSF50447 466 593 3.95E-26 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Pfam PF14578 Elongation factor Tu domain 4 468 554 1.2E-29 T 23-10-2018 IPR029459 Elongation factor Tu-type domain TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Gene3D G3DSA:2.40.30.10 467 557 6.2E-31 T 23-10-2018 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Pfam PF03144 Elongation factor Tu domain 2 248 326 1.1E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Pfam PF11987 Translation-initiation factor 2 351 447 8.7E-24 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 SUPERFAMILY SSF52540 6 289 1.82E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 SUPERFAMILY SSF52156 335 461 5.75E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 4 595 6.6E-247 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 3 597 44.055 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Gene3D G3DSA:3.40.50.10050 350 458 3.4E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Gene3D G3DSA:2.40.30.10 229 339 6.4E-41 T 23-10-2018 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 161 1.8E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_138 5914feb35e9f6f8f4d5970fa02d7f95c 598 Gene3D G3DSA:3.40.50.300 2 228 3.9E-65 T 23-10-2018 TAM4_512 40bd1733b6af2d34f7bfddd9888050ff 331 Pfam PF13421 SPFH domain-Band 7 family 16 204 8.7E-36 T 23-10-2018 IPR033880 SPFH domain, YdjI-like TAM4_512 40bd1733b6af2d34f7bfddd9888050ff 331 Pfam PF12773 Double zinc ribbon 286 327 1.4E-10 T 23-10-2018 IPR025874 Double zinc ribbon TAM4_512 40bd1733b6af2d34f7bfddd9888050ff 331 SUPERFAMILY SSF117892 75 203 2.48E-13 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TAM4_1610 dd62a3cb638ad6f80ece151a603391ac 249 Pfam PF05763 Protein of unknown function (DUF835) 129 243 7.1E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1288 77c47c8603588b2ea657759d8ef988d3 171 Pfam PF05683 Fumarase C-terminus 2 170 2.3E-41 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TAM4_1288 77c47c8603588b2ea657759d8ef988d3 171 SUPERFAMILY SSF117457 4 170 4.58E-54 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TAM4_1288 77c47c8603588b2ea657759d8ef988d3 171 Gene3D G3DSA:3.20.130.10 1 171 9.4E-68 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TAM4_1288 77c47c8603588b2ea657759d8ef988d3 171 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 171 2.1E-59 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TAM4_684 d2b2239639c0a69e3b066d53c42588d2 606 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 585 604 5.1E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 Gene3D G3DSA:3.40.50.920 253 391 2.6E-38 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 Gene3D G3DSA:3.40.50.970 3 252 5.6E-104 T 23-10-2018 TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 2.2E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 SUPERFAMILY SSF52518 5 251 1.64E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 8.5E-28 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TAM4_1335 849c32ca02c2a95be2912359f0f92571 394 SUPERFAMILY SSF52922 254 369 2.0E-31 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 Gene3D G3DSA:1.20.120.1190 1 161 4.0E-57 T 23-10-2018 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 Gene3D G3DSA:3.40.50.300 162 355 7.8E-58 T 23-10-2018 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 SUPERFAMILY SSF52540 77 282 4.43E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 SUPERFAMILY SSF52540 168 348 1.48E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 3.3E-23 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 TAM4_991 0086041c52111fc0ce2dedc60d25da96 356 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 328 1.9E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 SUPERFAMILY SSF75689 106 141 2.88E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 Gene3D G3DSA:3.30.70.3150 40 130 7.2E-33 T 23-10-2018 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 Pfam PF01873 Domain found in IF2B/IF5 23 135 1.3E-36 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 SMART SM00653 29 136 1.7E-58 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 8 142 33.625 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 9 141 2.5E-51 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TAM4_266 1a7629516ee377a58adc96957558fd6a 142 SUPERFAMILY SSF100966 8 109 7.06E-28 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TAM4_1292 c9af5fc69ca2f6ec20943c0b56d4ab21 143 Pfam PF01934 Protein of unknown function DUF86 18 133 9.5E-29 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TAM4_1292 c9af5fc69ca2f6ec20943c0b56d4ab21 143 Gene3D G3DSA:1.20.120.580 2 143 2.2E-25 T 23-10-2018 IPR037038 Bsu32300-like superfamily TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 Gene3D G3DSA:3.30.1430.10 77 188 7.4E-123 T 23-10-2018 TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 345 7.5E-137 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 Pfam PF00297 Ribosomal protein L3 3 346 1.3E-91 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 346 49.609 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 SUPERFAMILY SSF50447 3 346 5.21E-96 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 Gene3D G3DSA:2.40.30.10 39 326 7.4E-123 T 23-10-2018 TAM4_335 94f5a2abbd4f067108e8b38eb2bba2f1 346 Gene3D G3DSA:4.10.960.10 6 257 7.4E-123 T 23-10-2018 TAM4_719 454b7b64d0211a900d5b99668c1bd234 174 Pfam PF13247 4Fe-4S dicluster domain 42 134 1.9E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_719 454b7b64d0211a900d5b99668c1bd234 174 SUPERFAMILY SSF54862 1 149 2.2E-52 T 23-10-2018 TAM4_719 454b7b64d0211a900d5b99668c1bd234 174 Gene3D G3DSA:3.30.70.20 30 163 6.8E-40 T 23-10-2018 TAM4_719 454b7b64d0211a900d5b99668c1bd234 174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_1665 8b356b5a5a8fa014eaf9db807ce7f8a6 184 SUPERFAMILY SSF109604 1 169 3.81E-42 T 23-10-2018 TAM4_1665 8b356b5a5a8fa014eaf9db807ce7f8a6 184 Gene3D G3DSA:1.10.3210.10 1 181 6.6E-58 T 23-10-2018 TAM4_1665 8b356b5a5a8fa014eaf9db807ce7f8a6 184 Pfam PF13023 HD domain 9 149 4.8E-26 T 23-10-2018 IPR006674 HD domain TAM4_1665 8b356b5a5a8fa014eaf9db807ce7f8a6 184 SMART SM00471 26 144 4.5E-14 T 23-10-2018 IPR003607 HD/PDEase domain TAM4_838 076df348d0fb273166ab2ccc10aa6e71 128 Pfam PF11469 Ribonuclease III 10 127 1.7E-52 T 23-10-2018 IPR021568 Ribonuclease III, archaeal TAM4_838 076df348d0fb273166ab2ccc10aa6e71 128 SUPERFAMILY SSF69065 7 127 1.75E-43 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TAM4_838 076df348d0fb273166ab2ccc10aa6e71 128 Gene3D G3DSA:1.10.1520.20 2 128 1.3E-45 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal TAM4_1899 d78baff7630aea4450b1868df49abc38 277 Gene3D G3DSA:3.40.630.30 1 150 7.2E-24 T 23-10-2018 TAM4_1899 d78baff7630aea4450b1868df49abc38 277 Pfam PF00583 Acetyltransferase (GNAT) family 52 141 2.0E-15 T 23-10-2018 IPR000182 GNAT domain TAM4_1899 d78baff7630aea4450b1868df49abc38 277 SUPERFAMILY SSF55729 1 189 1.8E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1572 94c616e4da43320bd264a8e8a2c37c83 267 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 267 26.687 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 TAM4_1572 94c616e4da43320bd264a8e8a2c37c83 267 Gene3D G3DSA:3.10.270.10 1 266 2.8E-68 T 23-10-2018 TAM4_1572 94c616e4da43320bd264a8e8a2c37c83 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 4 263 1.6E-66 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 TAM4_1293 0ffc4df88710084de80aa3767d127383 302 Pfam PF03168 Late embryogenesis abundant protein 187 280 1.9E-8 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup TAM4_1293 0ffc4df88710084de80aa3767d127383 302 SMART SM00769 164 287 1.8E-5 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 TAM4_1293 0ffc4df88710084de80aa3767d127383 302 SUPERFAMILY SSF117070 151 253 1.05E-12 T 23-10-2018 TAM4_1293 0ffc4df88710084de80aa3767d127383 302 Gene3D G3DSA:2.60.40.10 29 148 2.0E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1293 0ffc4df88710084de80aa3767d127383 302 Gene3D G3DSA:2.60.40.10 163 298 1.1E-23 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_361 2261ab080d06dbb4a88586d9c179ebb5 890 SUPERFAMILY SSF103647 119 161 1.12E-5 T 23-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TAM4_1286 e2601200536704c53b6403dff2c9697d 325 SUPERFAMILY SSF52402 38 272 2.87E-54 T 23-10-2018 TAM4_1286 e2601200536704c53b6403dff2c9697d 325 Pfam PF01171 PP-loop family 52 230 7.4E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TAM4_1286 e2601200536704c53b6403dff2c9697d 325 PIRSF PIRSF004976 1 319 2.8E-111 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TAM4_1286 e2601200536704c53b6403dff2c9697d 325 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 206 307 2.5E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TAM4_1286 e2601200536704c53b6403dff2c9697d 325 Gene3D G3DSA:3.40.50.620 4 320 6.9E-86 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_518 3e2836167eafd7c95f34a68d5326f07a 211 SUPERFAMILY SSF46955 148 186 7.87E-5 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TAM4_518 3e2836167eafd7c95f34a68d5326f07a 211 Pfam PF14358 Domain of unknown function (DUF4405) 10 73 1.7E-15 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 TAM4_518 3e2836167eafd7c95f34a68d5326f07a 211 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 145 181 1.0E-6 T 23-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Gene3D G3DSA:1.10.10.1100 397 473 5.5E-143 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 256 1.3E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 259 351 9.3E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 87 2.9E-15 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 SUPERFAMILY SSF51905 109 368 1.88E-21 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 1.5E-6 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 1.5E-6 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 316 1.5E-6 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Gene3D G3DSA:3.10.20.440 1 95 1.6E-38 T 23-10-2018 TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Gene3D G3DSA:3.50.50.60 110 479 5.5E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_710 6ae019e1801956b5b8b1a28fd5cf3b79 492 Gene3D G3DSA:3.50.50.60 218 308 5.5E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_2091 d183d5917a4beaf93bdaf2a710ecec1a 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 70 81 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_2091 d183d5917a4beaf93bdaf2a710ecec1a 89 SUPERFAMILY SSF54862 20 88 2.3E-15 T 23-10-2018 TAM4_2091 d183d5917a4beaf93bdaf2a710ecec1a 89 Gene3D G3DSA:3.30.70.20 2 89 1.2E-16 T 23-10-2018 TAM4_2091 d183d5917a4beaf93bdaf2a710ecec1a 89 Pfam PF12838 4Fe-4S dicluster domain 33 81 3.1E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_2091 d183d5917a4beaf93bdaf2a710ecec1a 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_280 41affc07b633c341ed3eb074851f0b49 127 Pfam PF01655 Ribosomal protein L32 18 125 7.7E-41 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_280 41affc07b633c341ed3eb074851f0b49 127 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_280 41affc07b633c341ed3eb074851f0b49 127 SUPERFAMILY SSF52042 5 126 5.89E-47 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_280 41affc07b633c341ed3eb074851f0b49 127 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 21 125 5.0E-54 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_280 41affc07b633c341ed3eb074851f0b49 127 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.98 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 TAM4_280 41affc07b633c341ed3eb074851f0b49 127 SMART SM01393 18 125 1.2E-63 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1116 7f9d9c9a09642b2dd6f9e168a01b1a5c 468 SUPERFAMILY SSF50249 377 460 5.14E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1116 7f9d9c9a09642b2dd6f9e168a01b1a5c 468 Gene3D G3DSA:2.40.50.140 358 468 4.8E-6 T 23-10-2018 TAM4_1116 7f9d9c9a09642b2dd6f9e168a01b1a5c 468 SUPERFAMILY SSF50249 178 251 3.26E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_375 7396b869cb511cbbb484716e1e3027e9 152 Gene3D G3DSA:3.30.1440.10 2 148 1.6E-46 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_375 7396b869cb511cbbb484716e1e3027e9 152 Pfam PF01877 RNA binding 8 130 3.8E-39 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TAM4_375 7396b869cb511cbbb484716e1e3027e9 152 SUPERFAMILY SSF55282 6 148 7.06E-43 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 316 345 0.038 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 79 109 0.0062 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 Gene3D G3DSA:1.50.10.20 381 603 1.5E-10 T 23-10-2018 TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 SUPERFAMILY SSF48239 313 518 1.05E-19 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 SUPERFAMILY SSF48239 59 362 1.1E-24 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 Gene3D G3DSA:1.50.10.20 30 169 2.2E-15 T 23-10-2018 TAM4_814 4eda50fbd27127ca575048ef1fce3b42 754 Gene3D G3DSA:1.50.10.20 283 367 2.3E-7 T 23-10-2018 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 Pfam PF01912 eIF-6 family 5 206 4.7E-71 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 2.8E-65 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 PIRSF PIRSF006413 2 228 9.2E-80 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 Gene3D G3DSA:3.75.10.10 1 227 7.6E-81 T 23-10-2018 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 SMART SM00654 4 206 2.3E-102 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 98.678 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TAM4_1531 52baa2c2f5e557819f50e165d4fb1af9 228 SUPERFAMILY SSF55909 3 226 3.92E-76 T 23-10-2018 TAM4_2368 0b2f0c30356160a6981951cb0c714c7f 83 Pfam PF04457 Protein of unknown function (DUF504) 26 78 1.2E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TAM4_2368 0b2f0c30356160a6981951cb0c714c7f 83 Hamap MF_01245 UPF0248 protein . 10 79 19.386 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TAM4_1278 42d70d95abe949cfbe4f56393fb7bde5 277 Pfam PF05763 Protein of unknown function (DUF835) 137 264 5.1E-32 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 SUPERFAMILY SSF75217 1 174 1.07E-68 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 176 43.691 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 PIRSF PIRSF016123 1 178 1.4E-85 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 177 3.0E-58 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 174 1.4E-50 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TAM4_2086 d648350a29c5b4d8bd82829dc8891662 178 Gene3D G3DSA:3.40.1280.10 1 177 3.1E-79 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TAM4_1689 ca4e801ca54db85c952537b7189c5ec3 329 Gene3D G3DSA:3.40.1750.20 184 250 7.4E-56 T 23-10-2018 TAM4_1689 ca4e801ca54db85c952537b7189c5ec3 329 Pfam PF01343 Peptidase family S49 144 293 2.2E-39 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TAM4_1689 ca4e801ca54db85c952537b7189c5ec3 329 SUPERFAMILY SSF52096 81 279 3.42E-36 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TAM4_1689 ca4e801ca54db85c952537b7189c5ec3 329 Gene3D G3DSA:3.90.226.10 88 287 7.4E-56 T 23-10-2018 TAM4_1689 ca4e801ca54db85c952537b7189c5ec3 329 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 86 292 1.4E-64 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TAM4_1107 3aeac1fe55ae9860ac3397317a392d74 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 5.6E-80 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TAM4_1107 3aeac1fe55ae9860ac3397317a392d74 185 SUPERFAMILY SSF53323 1 179 2.09E-58 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_1107 3aeac1fe55ae9860ac3397317a392d74 185 Gene3D G3DSA:3.40.920.10 1 182 5.7E-74 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_1107 3aeac1fe55ae9860ac3397317a392d74 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 9.5E-44 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TAM4_639 ac812abf3226398a246e9e5c4451b924 110 Gene3D G3DSA:1.10.10.10 4 110 1.0E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_639 ac812abf3226398a246e9e5c4451b924 110 SUPERFAMILY SSF46785 7 109 9.52E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_639 ac812abf3226398a246e9e5c4451b924 110 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 15 86 3.5E-10 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 PIRSF PIRSF037420 290 369 8.9E-7 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 PIRSF PIRSF037420 21 220 3.1E-24 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 SUPERFAMILY SSF102114 28 341 2.49E-54 T 23-10-2018 TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 Pfam PF04055 Radical SAM superfamily 31 195 2.0E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 Gene3D G3DSA:3.20.20.70 22 316 3.3E-45 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 Pfam PF13394 4Fe-4S single cluster domain 34 118 8.9E-7 T 23-10-2018 TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 Pfam PF13186 Iron-sulfur cluster-binding domain 258 336 3.5E-17 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 25 371 7.8E-152 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase TAM4_35 9299c2a3a06d6b0d6260bddca616dd55 381 SMART SM00729 27 231 0.0098 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1826 dfcc75eb4fd3d703d8b561f00cd9ede3 442 Gene3D G3DSA:3.30.2290.10 3 184 2.3E-9 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_1826 dfcc75eb4fd3d703d8b561f00cd9ede3 442 PIRSF PIRSF004919 1 441 8.8E-114 T 23-10-2018 IPR025502 TldD TAM4_1826 dfcc75eb4fd3d703d8b561f00cd9ede3 442 Pfam PF01523 Putative modulator of DNA gyrase 37 297 1.5E-35 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_1826 dfcc75eb4fd3d703d8b561f00cd9ede3 442 SUPERFAMILY SSF111283 3 436 8.76E-78 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 Pfam PF02545 Maf-like protein 2 174 5.0E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 31.088 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 174 2.5E-48 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 PIRSF PIRSF006305 1 184 7.0E-60 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 Gene3D G3DSA:3.90.950.10 1 182 2.6E-65 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TAM4_57 f0ae3fac3722c8578396f0c1b4c9cb1e 186 SUPERFAMILY SSF52972 1 175 2.43E-58 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 SUPERFAMILY SSF56228 3 228 2.35E-44 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 SUPERFAMILY SSF48310 254 650 9.55E-66 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 1.8E-40 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 Gene3D G3DSA:1.10.569.10 280 473 6.7E-12 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 SMART SM00790 1 226 2.6E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 576 1.1E-17 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_1410 40ec5f43705a1c9e2ea4bfba9cb3ff55 652 Gene3D G3DSA:3.60.9.10 2 228 7.5E-24 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 SUPERFAMILY SSF47807 221 338 2.09E-33 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 Gene3D G3DSA:1.10.150.20 221 281 2.2E-20 T 23-10-2018 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 9.3E-157 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 SUPERFAMILY SSF88723 7 236 4.91E-66 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 1.0E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 1.0E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 1.0E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 1.0E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 1.0E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 Gene3D G3DSA:3.40.50.1010 1 220 2.8E-88 T 23-10-2018 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 Pfam PF00752 XPG N-terminal domain 12 101 4.7E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 SMART SM00485 1 101 6.9E-51 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 SMART SM00279 223 257 2.4E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 Pfam PF00867 XPG I-region 141 236 2.7E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 SMART SM00484 140 221 2.2E-37 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 339 147.257 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 TAM4_2204 29981379b78ae9e0692ed3df87aa81f7 339 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 TAM4_1251 99185380e3c3143db88df6a8701829e2 108 SUPERFAMILY SSF81301 2 108 7.2E-24 T 23-10-2018 TAM4_1251 99185380e3c3143db88df6a8701829e2 108 Pfam PF01909 Nucleotidyltransferase domain 13 89 1.1E-13 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1251 99185380e3c3143db88df6a8701829e2 108 Gene3D G3DSA:3.30.460.10 3 104 1.6E-19 T 23-10-2018 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Gene3D G3DSA:3.40.50.200 80 392 3.2E-138 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 151 161 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Gene3D G3DSA:3.30.70.80 1 79 5.5E-31 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 329 339 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 PRINTS PR00723 Subtilisin serine protease family (S8) signature 147 160 2.0E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 PRINTS PR00723 Subtilisin serine protease family (S8) signature 109 128 2.0E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 PRINTS PR00723 Subtilisin serine protease family (S8) signature 328 344 2.0E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Pfam PF00082 Subtilase family 109 380 2.1E-66 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 SUPERFAMILY SSF49785 403 476 4.0E-6 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 114 125 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 415 472 1.7E-5 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 532 597 9.5E-9 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 PIRSF PIRSF037907 1 616 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Gene3D G3DSA:2.60.120.380 518 614 2.8E-14 T 23-10-2018 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 Gene3D G3DSA:2.60.120.380 393 494 1.0E-23 T 23-10-2018 TAM4_1096 21e92751f2a2d7e82e22276ea049679d 616 SUPERFAMILY SSF52743 99 389 7.99E-91 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TAM4_2147 e512d0af6b35839b7d5ba7e4e6c4b333 166 SUPERFAMILY SSF47240 17 159 6.54E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_2147 e512d0af6b35839b7d5ba7e4e6c4b333 166 Pfam PF02915 Rubrerythrin 24 153 2.8E-18 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2147 e512d0af6b35839b7d5ba7e4e6c4b333 166 Gene3D G3DSA:1.20.1260.10 8 159 1.5E-35 T 23-10-2018 IPR012347 Ferritin-like TAM4_2477 94ca7cde3231eb9c9958816b76fb6518 211 Gene3D G3DSA:3.40.50.300 5 208 3.4E-34 T 23-10-2018 TAM4_2409 e31437d4cb37507c9cba67bdd594e690 140 SUPERFAMILY SSF117856 3 129 5.49E-37 T 23-10-2018 TAM4_2409 e31437d4cb37507c9cba67bdd594e690 140 PIRSF PIRSF016702 1 139 1.0E-44 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif TAM4_2409 e31437d4cb37507c9cba67bdd594e690 140 Gene3D G3DSA:3.30.1330.80 1 140 1.2E-51 T 23-10-2018 TAM4_2409 e31437d4cb37507c9cba67bdd594e690 140 Pfam PF03479 Domain of unknown function (DUF296) 8 119 4.0E-21 T 23-10-2018 IPR005175 PPC domain TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Gene3D G3DSA:3.90.1570.50 94 234 3.3E-18 T 23-10-2018 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 11 187 1.4E-34 T 23-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Pfam PF11867 Domain of unknown function (DUF3387) 689 954 7.8E-7 T 23-10-2018 IPR021810 Protein of unknown function DUF3387 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 11 682 1.6E-222 T 23-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 SUPERFAMILY SSF52540 200 459 4.85E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Pfam PF04851 Type III restriction enzyme, res subunit 242 417 1.4E-18 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 SMART SM00487 238 453 3.2E-14 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 SUPERFAMILY SSF52540 383 645 1.21E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Gene3D G3DSA:3.40.50.300 241 440 5.7E-44 T 23-10-2018 TAM4_1568 094ed654e25b20c81022b771a6a9cf18 983 Gene3D G3DSA:3.40.50.300 441 688 1.8E-40 T 23-10-2018 TAM4_658 73f8287a89c42bbca31a54496591b291 165 Gene3D G3DSA:3.30.428.10 1 163 3.8E-59 T 23-10-2018 IPR036265 HIT-like superfamily TAM4_658 73f8287a89c42bbca31a54496591b291 165 SUPERFAMILY SSF54197 2 158 3.4E-47 T 23-10-2018 IPR036265 HIT-like superfamily TAM4_658 73f8287a89c42bbca31a54496591b291 165 Pfam PF01230 HIT domain 35 125 2.7E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TAM4_92 03cefd5c3177b6c8976804286a86ce99 199 Pfam PF14544 Domain of unknown function (DUF4443) 80 188 1.0E-57 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 TAM4_92 03cefd5c3177b6c8976804286a86ce99 199 Gene3D G3DSA:1.10.10.10 1 81 2.2E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_92 03cefd5c3177b6c8976804286a86ce99 199 SUPERFAMILY SSF55261 88 197 1.7E-39 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TAM4_92 03cefd5c3177b6c8976804286a86ce99 199 Gene3D G3DSA:3.30.1360.30 82 190 8.8E-47 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TAM4_92 03cefd5c3177b6c8976804286a86ce99 199 SUPERFAMILY SSF46785 17 76 1.9E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1457 a743d417282096c5c4efb5e905cc18e6 623 Gene3D G3DSA:3.40.50.1820 353 623 3.8E-82 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_1457 a743d417282096c5c4efb5e905cc18e6 623 SUPERFAMILY SSF82171 23 339 7.59E-23 T 23-10-2018 TAM4_1457 a743d417282096c5c4efb5e905cc18e6 623 Gene3D G3DSA:2.120.10.30 17 135 5.0E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TAM4_1457 a743d417282096c5c4efb5e905cc18e6 623 SUPERFAMILY SSF53474 355 605 2.01E-57 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_1457 a743d417282096c5c4efb5e905cc18e6 623 Pfam PF00326 Prolyl oligopeptidase family 397 606 3.9E-53 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TAM4_1620 e361aee8ccf53c4966dcd136a2a76cf9 212 Gene3D G3DSA:3.40.630.30 1 141 2.3E-24 T 23-10-2018 TAM4_1620 e361aee8ccf53c4966dcd136a2a76cf9 212 SUPERFAMILY SSF55729 1 139 2.1E-26 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1620 e361aee8ccf53c4966dcd136a2a76cf9 212 Pfam PF00583 Acetyltransferase (GNAT) family 34 130 1.6E-16 T 23-10-2018 IPR000182 GNAT domain TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 Gene3D G3DSA:1.20.120.920 83 326 1.7E-67 T 23-10-2018 TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 311 25.39 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 Pfam PF01867 CRISPR associated protein Cas1 8 281 1.3E-85 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 Gene3D G3DSA:3.100.10.20 1 82 8.7E-29 T 23-10-2018 TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 325 4.7E-133 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 TAM4_1903 08eac4e35d177c833516cc8b52f7ff7b 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 321 3.6E-97 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TAM4_628 23044a592df4d7f167e6c3876f1686ec 112 PIRSF PIRSF016134 2 111 1.7E-46 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TAM4_628 23044a592df4d7f167e6c3876f1686ec 112 SMART SM01022 6 109 7.3E-12 T 23-10-2018 IPR007374 ASCH domain TAM4_628 23044a592df4d7f167e6c3876f1686ec 112 Gene3D G3DSA:2.30.130.30 1 111 5.6E-40 T 23-10-2018 TAM4_628 23044a592df4d7f167e6c3876f1686ec 112 Pfam PF04266 ASCH domain 7 108 5.7E-14 T 23-10-2018 IPR007374 ASCH domain TAM4_628 23044a592df4d7f167e6c3876f1686ec 112 SUPERFAMILY SSF88697 1 108 1.62E-32 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_1848 e5a28e33cac8b4e2c7d110fcedac3ddb 232 SUPERFAMILY SSF51366 1 224 3.61E-50 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TAM4_1848 e5a28e33cac8b4e2c7d110fcedac3ddb 232 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 225 29.143 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TAM4_1848 e5a28e33cac8b4e2c7d110fcedac3ddb 232 Pfam PF00977 Histidine biosynthesis protein 3 217 7.6E-54 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TAM4_1848 e5a28e33cac8b4e2c7d110fcedac3ddb 232 Gene3D G3DSA:3.20.20.70 1 228 5.5E-66 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Gene3D G3DSA:3.30.56.10 1 80 1.2E-22 T 23-10-2018 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Gene3D G3DSA:3.30.56.10 279 348 1.8E-26 T 23-10-2018 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 557 2.3E-176 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Gene3D G3DSA:3.50.40.10 81 278 3.0E-74 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SMART SM00873 100 259 1.7E-20 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SUPERFAMILY SSF46955 5 81 7.23E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 35.979 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SUPERFAMILY SSF55681 345 562 8.28E-44 T 23-10-2018 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Gene3D G3DSA:3.30.930.10 365 563 1.2E-51 T 23-10-2018 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SUPERFAMILY SSF56037 142 259 2.41E-5 T 23-10-2018 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 8.1E-14 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 Pfam PF03483 B3/4 domain 117 243 1.0E-15 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SMART SM00874 280 348 3.9E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TAM4_2117 d888a80c4c5c7d2065a2b76d5483d966 568 SUPERFAMILY SSF46955 281 352 5.13E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TAM4_1378 cc38f9b32d649f2d86512fa52f157802 827 Gene3D G3DSA:3.40.190.10 374 522 1.2E-5 T 23-10-2018 TAM4_1378 cc38f9b32d649f2d86512fa52f157802 827 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 807 826 5.7E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1378 cc38f9b32d649f2d86512fa52f157802 827 SUPERFAMILY SSF53850 408 730 9.77E-21 T 23-10-2018 TAM4_1378 cc38f9b32d649f2d86512fa52f157802 827 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 400 713 2.6E-15 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TAM4_1378 cc38f9b32d649f2d86512fa52f157802 827 Gene3D G3DSA:3.10.105.10 533 742 3.6E-15 T 23-10-2018 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 62 29.532 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 62 3.0E-17 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 SMART SM01389 4 62 9.4E-32 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 SUPERFAMILY SSF63393 3 62 1.75E-23 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 61 6.0E-15 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TAM4_736 c5a12e82e56db19f9c3b2ca9e2300eb8 62 Gene3D G3DSA:2.20.28.90 1 62 5.9E-33 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily TAM4_181 76a9b6fcd910cecb90ae281fa94cc9f8 326 Pfam PF00483 Nucleotidyl transferase 1 228 2.2E-34 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_181 76a9b6fcd910cecb90ae281fa94cc9f8 326 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 248 276 0.0017 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_181 76a9b6fcd910cecb90ae281fa94cc9f8 326 Gene3D G3DSA:2.160.10.10 234 324 1.2E-6 T 23-10-2018 TAM4_181 76a9b6fcd910cecb90ae281fa94cc9f8 326 Gene3D G3DSA:3.90.550.10 1 233 6.5E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_181 76a9b6fcd910cecb90ae281fa94cc9f8 326 SUPERFAMILY SSF53448 1 281 5.88E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_66 2430f913dd98a7017af7c7fc52903932 90 Pfam PF03683 Uncharacterised protein family (UPF0175) 18 85 8.6E-15 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 TAM4_929 f04c5c5706fb796b78da9e19def44265 263 Pfam PF00795 Carbon-nitrogen hydrolase 3 242 9.5E-57 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TAM4_929 f04c5c5706fb796b78da9e19def44265 263 Gene3D G3DSA:3.60.110.10 1 263 4.2E-102 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TAM4_929 f04c5c5706fb796b78da9e19def44265 263 SUPERFAMILY SSF56317 1 261 3.53E-75 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TAM4_1236 f77f1dfc581e1be18cbb40532e4e988b 204 Pfam PF01914 MarC family integral membrane protein 5 196 6.9E-32 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 390 2.9E-118 T 23-10-2018 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 SUPERFAMILY SSF51338 13 397 7.82E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 395 64.061 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 ProSitePatterns PS00483 Dihydroorotase signature 2. 274 285 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 Gene3D G3DSA:3.20.20.140 42 406 1.7E-106 T 23-10-2018 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 Pfam PF01979 Amidohydrolase family 49 217 4.2E-12 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TAM4_1240 963c1df5efd69a7fb0e32b941e91bc9c 407 SUPERFAMILY SSF51556 52 334 4.54E-73 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_932 eb8538f1ffcc7796784e929fe71bfc64 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 15.128 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG TAM4_932 eb8538f1ffcc7796784e929fe71bfc64 56 Pfam PF03911 Sec61beta family 11 51 1.4E-16 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_932 eb8538f1ffcc7796784e929fe71bfc64 56 ProDom PD048325 SUBUNIT PREPROTEIN TRANSLOCASE SECG HOMOLOG TRANSLOCATION MEMBRANE SEC61 TRANSMEMBRANE BETA 1 39 0.003 T 23-10-2018 TAM4_1357 ea41fafef5534c5eeecb07c658f8374a 285 Pfam PF08241 Methyltransferase domain 130 233 2.1E-10 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TAM4_1357 ea41fafef5534c5eeecb07c658f8374a 285 SUPERFAMILY SSF53335 81 261 5.63E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1357 ea41fafef5534c5eeecb07c658f8374a 285 Gene3D G3DSA:3.40.50.150 95 275 7.7E-27 T 23-10-2018 TAM4_1700 abf59079e0aabde9316861cdf2917d26 260 Pfam PF00696 Amino acid kinase family 2 231 1.4E-41 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TAM4_1700 abf59079e0aabde9316861cdf2917d26 260 SUPERFAMILY SSF53633 2 259 5.63E-33 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_1700 abf59079e0aabde9316861cdf2917d26 260 PIRSF PIRSF016496 1 260 5.6E-79 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 TAM4_1700 abf59079e0aabde9316861cdf2917d26 260 Gene3D G3DSA:3.40.1160.10 1 260 4.9E-59 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_554 317ea80e17d52d7ea7e195cd58ecd952 196 Gene3D G3DSA:1.10.10.10 1 103 3.4E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_554 317ea80e17d52d7ea7e195cd58ecd952 196 SMART SM00418 7 87 1.1E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_554 317ea80e17d52d7ea7e195cd58ecd952 196 SUPERFAMILY SSF46785 1 170 2.96E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_554 317ea80e17d52d7ea7e195cd58ecd952 196 Pfam PF01022 Bacterial regulatory protein, arsR family 14 59 2.5E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_675 7f948d764a03eff7e56120766435c753 242 SUPERFAMILY SSF52540 3 239 4.98E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_675 7f948d764a03eff7e56120766435c753 242 Pfam PF06745 KaiC 8 238 2.7E-31 T 23-10-2018 IPR014774 KaiC-like domain TAM4_675 7f948d764a03eff7e56120766435c753 242 Gene3D G3DSA:3.40.50.300 2 241 1.2E-36 T 23-10-2018 TAM4_979 9a3a3965abac0e22e6b8a7db1fbfbc09 199 Gene3D G3DSA:3.30.460.80 7 155 2.8E-27 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_979 9a3a3965abac0e22e6b8a7db1fbfbc09 199 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 111 152 8.0E-15 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_979 9a3a3965abac0e22e6b8a7db1fbfbc09 199 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 61 175 4.8E-31 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_979 9a3a3965abac0e22e6b8a7db1fbfbc09 199 SUPERFAMILY SSF143243 52 185 1.12E-34 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1505 2f19deca3cbe0e859a50deba2cac202d 250 SUPERFAMILY SSF161098 7 241 1.05E-46 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1505 2f19deca3cbe0e859a50deba2cac202d 250 Gene3D G3DSA:1.10.3720.10 5 249 1.9E-64 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1505 2f19deca3cbe0e859a50deba2cac202d 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 243 8.5E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 SUPERFAMILY SSF46785 237 315 3.24E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 SUPERFAMILY SSF52980 338 399 6.08E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 Pfam PF01637 ATPase domain predominantly from Archaea 6 197 2.3E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 SUPERFAMILY SSF52540 4 236 1.82E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 Pfam PF03008 Archaea bacterial proteins of unknown function 306 405 3.5E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_160 ecb791b559e9414e90a3dd4e003d64d6 460 Gene3D G3DSA:3.40.50.300 2 163 1.9E-25 T 23-10-2018 TAM4_1957 e0f63b7e8958aae1e9139cda43a00cc8 524 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 322 334 3.1E-7 T 23-10-2018 TAM4_1957 e0f63b7e8958aae1e9139cda43a00cc8 524 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 3.1E-7 T 23-10-2018 TAM4_1957 e0f63b7e8958aae1e9139cda43a00cc8 524 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 3.1E-7 T 23-10-2018 TAM4_1957 e0f63b7e8958aae1e9139cda43a00cc8 524 Pfam PF00361 Proton-conducting membrane transporter 132 431 6.8E-56 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 Gene3D G3DSA:3.40.50.1820 1 258 4.3E-68 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 SUPERFAMILY SSF53474 10 253 5.85E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 Pfam PF12146 Serine aminopeptidase, S33 14 240 2.3E-67 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 6.9E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 6.9E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 6.9E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TAM4_630 5b022e685fb600601a8f9e9020b39a3e 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 6.9E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TAM4_2116 42ca0ab79f5e8c26b35d71c13add85fa 91 Gene3D G3DSA:3.30.460.10 1 89 2.3E-15 T 23-10-2018 TAM4_2116 42ca0ab79f5e8c26b35d71c13add85fa 91 Pfam PF01909 Nucleotidyltransferase domain 7 50 1.8E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_2116 42ca0ab79f5e8c26b35d71c13add85fa 91 SUPERFAMILY SSF81301 7 91 1.19E-18 T 23-10-2018 TAM4_954 44cd617c5e51eec43dd279a445c0378b 371 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 171 210 3.0E-4 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TAM4_954 44cd617c5e51eec43dd279a445c0378b 371 Gene3D G3DSA:3.40.1280.30 92 269 2.9E-10 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily TAM4_954 44cd617c5e51eec43dd279a445c0378b 371 PIRSF PIRSF018978 3 371 8.9E-181 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 TAM4_1260 95879aa4b5fd7a61d60bcbbcb0666f76 75 SUPERFAMILY SSF54909 1 74 2.41E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_1260 95879aa4b5fd7a61d60bcbbcb0666f76 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.6E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_1260 95879aa4b5fd7a61d60bcbbcb0666f76 75 Gene3D G3DSA:3.30.70.920 1 74 9.6E-28 T 23-10-2018 TAM4_1305 16551f711109bb23b53883c6653c3e20 312 SUPERFAMILY SSF51556 3 311 8.39E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_1305 16551f711109bb23b53883c6653c3e20 312 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 3 309 3.5E-88 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TAM4_1305 16551f711109bb23b53883c6653c3e20 312 Gene3D G3DSA:3.20.20.140 1 311 1.2E-87 T 23-10-2018 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 SMART SM00919 158 388 2.4E-97 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 SUPERFAMILY SSF51735 158 415 8.74E-64 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 SUPERFAMILY SSF53223 11 156 5.18E-52 T 23-10-2018 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 ProSitePatterns PS00331 Malic enzymes signature. 154 170 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 Pfam PF03949 Malic enzyme, NAD binding domain 271 369 4.9E-9 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 Pfam PF03949 Malic enzyme, NAD binding domain 159 204 5.6E-7 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 Gene3D G3DSA:3.40.50.10380 1 155 5.0E-67 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 Gene3D G3DSA:3.40.50.720 156 428 5.6E-95 T 23-10-2018 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 PIRSF PIRSF000106 24 418 1.7E-77 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 SMART SM01274 14 146 3.5E-79 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TAM4_1317 15984bc1e9638c4286e1ed974010307e 428 Pfam PF00390 Malic enzyme, N-terminal domain 16 146 1.4E-27 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TAM4_1124 8ba4b24997dc746f791b041fbacc78dd 358 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 17 91 1.2E-23 T 23-10-2018 IPR010094 Transposase (putative), N-terminal TAM4_1701 1dc5321a787f54ab6182179953d130e6 502 Gene3D G3DSA:3.40.640.10 86 315 2.1E-59 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1701 1dc5321a787f54ab6182179953d130e6 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 60.765 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TAM4_1701 1dc5321a787f54ab6182179953d130e6 502 Pfam PF02347 Glycine cleavage system P-protein 33 306 7.6E-10 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TAM4_1701 1dc5321a787f54ab6182179953d130e6 502 Gene3D G3DSA:3.90.1150.10 340 475 8.0E-44 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1701 1dc5321a787f54ab6182179953d130e6 502 SUPERFAMILY SSF53383 12 488 7.84E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_2028 4d40703e9da0f6a732aba16cd6681e85 327 Pfam PF11741 AMIN domain 212 259 2.3E-4 T 23-10-2018 IPR021731 AMIN domain TAM4_2028 4d40703e9da0f6a732aba16cd6681e85 327 SMART SM00646 95 204 1.8E-39 T 23-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TAM4_2028 4d40703e9da0f6a732aba16cd6681e85 327 SUPERFAMILY SSF53187 35 209 5.65E-61 T 23-10-2018 TAM4_2028 4d40703e9da0f6a732aba16cd6681e85 327 Gene3D G3DSA:3.40.630.40 33 209 5.9E-64 T 23-10-2018 TAM4_2028 4d40703e9da0f6a732aba16cd6681e85 327 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 37 204 2.2E-55 T 23-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TAM4_831 24eb1dbebf2a7c8a3a23dda15c3207db 270 Pfam PF00753 Metallo-beta-lactamase superfamily 22 242 2.5E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_831 24eb1dbebf2a7c8a3a23dda15c3207db 270 SUPERFAMILY SSF56281 9 263 1.97E-34 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_831 24eb1dbebf2a7c8a3a23dda15c3207db 270 Gene3D G3DSA:3.60.15.10 1 269 7.5E-75 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_831 24eb1dbebf2a7c8a3a23dda15c3207db 270 SMART SM00849 21 242 1.0E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 SUPERFAMILY SSF55920 5 295 3.01E-66 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.624 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 3 295 1.8E-115 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 Gene3D G3DSA:1.10.10.10 196 272 1.7E-106 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 Pfam PF00557 Metallopeptidase family M24 6 287 3.2E-45 T 23-10-2018 IPR000994 Peptidase M24 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 Gene3D G3DSA:3.90.230.10 9 286 1.7E-106 T 23-10-2018 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 SUPERFAMILY SSF46785 196 271 4.08E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 1.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 1.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 1.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_975 560a5e5db70af7a78058df3b1cbfaa73 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 1.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TAM4_390 167caa3e0610185ab06e9c32904b7122 211 SMART SM00849 7 175 1.9E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_390 167caa3e0610185ab06e9c32904b7122 211 Pfam PF13483 Beta-lactamase superfamily domain 3 175 3.3E-28 T 23-10-2018 TAM4_390 167caa3e0610185ab06e9c32904b7122 211 SUPERFAMILY SSF56281 1 206 1.48E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_390 167caa3e0610185ab06e9c32904b7122 211 Gene3D G3DSA:3.60.15.10 1 197 9.1E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 Pfam PF02080 TrkA-C domain 118 176 1.0E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 Gene3D G3DSA:3.30.70.1450 111 190 8.3E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 SUPERFAMILY SSF116726 102 181 8.63E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 Gene3D G3DSA:1.20.58.220 1 109 2.5E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 Pfam PF01895 PhoU domain 11 95 5.0E-10 T 23-10-2018 IPR026022 PhoU domain TAM4_540 c4ba39dbcaf473d2cede473b8b3394d9 192 SUPERFAMILY SSF109755 2 97 4.06E-17 T 23-10-2018 TAM4_1824 ab3de74470b110cfe05a650f399b315d 650 Gene3D G3DSA:2.30.310.10 5 150 7.3E-32 T 23-10-2018 TAM4_1824 ab3de74470b110cfe05a650f399b315d 650 Pfam PF05670 Domain of unknown function (DUF814) 455 553 4.3E-25 T 23-10-2018 IPR008532 Domain of unknown function DUF814 TAM4_1824 ab3de74470b110cfe05a650f399b315d 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 436 4.5E-83 T 23-10-2018 TAM4_1685 1ed1b63b813418f11417941f938bb3dd 211 Gene3D G3DSA:3.40.50.10480 1 187 1.1E-32 T 23-10-2018 TAM4_1685 1ed1b63b813418f11417941f938bb3dd 211 SMART SM00879 3 190 4.6E-17 T 23-10-2018 IPR007109 Brix domain TAM4_1685 1ed1b63b813418f11417941f938bb3dd 211 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.223 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein TAM4_1685 1ed1b63b813418f11417941f938bb3dd 211 SUPERFAMILY SSF52954 1 193 5.43E-35 T 23-10-2018 TAM4_528 8737c2f1befe8883a781b10b8d1e4c78 187 Hamap MF_01842 Archaemetzincin [amzA]. 3 177 33.846 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TAM4_528 8737c2f1befe8883a781b10b8d1e4c78 187 Gene3D G3DSA:3.40.390.10 6 184 8.4E-50 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TAM4_528 8737c2f1befe8883a781b10b8d1e4c78 187 PIRSF PIRSF005785 1 186 5.1E-59 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TAM4_528 8737c2f1befe8883a781b10b8d1e4c78 187 Pfam PF07998 Peptidase family M54 2 177 1.2E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TAM4_528 8737c2f1befe8883a781b10b8d1e4c78 187 SUPERFAMILY SSF55486 65 172 1.37E-14 T 23-10-2018 TAM4_472 98c8a51a51d0967eb420276eaca73795 294 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 14 137 2.4E-19 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_472 98c8a51a51d0967eb420276eaca73795 294 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 176 279 3.4E-18 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_472 98c8a51a51d0967eb420276eaca73795 294 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 16 274 2.9E-42 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_2001 023e026b8f4c1679242f82e49b01e0a0 531 Gene3D G3DSA:3.40.190.10 153 388 1.5E-34 T 23-10-2018 TAM4_2001 023e026b8f4c1679242f82e49b01e0a0 531 Pfam PF13416 Bacterial extracellular solute-binding protein 158 401 2.8E-23 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TAM4_2001 023e026b8f4c1679242f82e49b01e0a0 531 SUPERFAMILY SSF53850 130 401 3.73E-44 T 23-10-2018 TAM4_2001 023e026b8f4c1679242f82e49b01e0a0 531 Gene3D G3DSA:3.40.190.10 222 341 1.5E-34 T 23-10-2018 TAM4_1290 dab448f1bf533857c90105a46b93dafe 127 Pfam PF03625 Domain of unknown function DUF302 43 96 6.7E-8 T 23-10-2018 IPR005180 Domain of unknown function DUF302 TAM4_1290 dab448f1bf533857c90105a46b93dafe 127 Gene3D G3DSA:3.30.310.70 6 126 5.5E-16 T 23-10-2018 IPR035923 TT1751-like domain superfamily TAM4_1290 dab448f1bf533857c90105a46b93dafe 127 SUPERFAMILY SSF103247 8 125 1.7E-20 T 23-10-2018 IPR035923 TT1751-like domain superfamily TAM4_290 68d78c643f9982ec8d9c966c94bf1dcd 212 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 187 1.3E-45 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TAM4_747 a6a43a2c94e235edcd2de266df758cf2 268 SUPERFAMILY SSF102114 9 185 5.49E-5 T 23-10-2018 TAM4_747 a6a43a2c94e235edcd2de266df758cf2 268 Pfam PF04055 Radical SAM superfamily 31 185 2.8E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 Gene3D G3DSA:3.40.50.1860 4 219 5.4E-89 T 23-10-2018 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 221 1.1E-62 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 SUPERFAMILY SSF53681 118 226 2.45E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 80 88 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 233 1.0E-110 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 Gene3D G3DSA:3.40.50.1860 106 213 5.4E-89 T 23-10-2018 TAM4_2057 8dd0cdfa3929e5f8f79fbac85c433a45 234 SUPERFAMILY SSF53681 3 116 3.11E-36 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_1529 c3667e0165394dfcf7643725b619f2d0 197 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 189 2.1E-52 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TAM4_1529 c3667e0165394dfcf7643725b619f2d0 197 Gene3D G3DSA:3.40.50.620 1 195 3.5E-52 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1529 c3667e0165394dfcf7643725b619f2d0 197 SUPERFAMILY SSF52402 2 156 1.4E-36 T 23-10-2018 TAM4_2139 ba73bfc2498bdcd67ba14222df883676 308 Pfam PF01699 Sodium/calcium exchanger protein 166 306 5.7E-29 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TAM4_2139 ba73bfc2498bdcd67ba14222df883676 308 Pfam PF01699 Sodium/calcium exchanger protein 8 146 1.3E-22 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TAM4_2139 ba73bfc2498bdcd67ba14222df883676 308 Gene3D G3DSA:1.20.58.1130 11 197 1.2E-79 T 23-10-2018 TAM4_2139 ba73bfc2498bdcd67ba14222df883676 308 Gene3D G3DSA:1.20.1420.30 38 299 1.2E-79 T 23-10-2018 TAM4_2139 ba73bfc2498bdcd67ba14222df883676 308 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 5 301 9.5E-62 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 TAM4_1310 1bf17736d341e422cf2819c2c881aedd 418 Gene3D G3DSA:2.120.10.30 19 223 6.3E-6 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TAM4_1310 1bf17736d341e422cf2819c2c881aedd 418 SUPERFAMILY SSF101898 14 284 4.45E-11 T 23-10-2018 TAM4_1932 49854682538aa1e5d284b972195e4eb6 249 Pfam PF01909 Nucleotidyltransferase domain 9 58 1.6E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1932 49854682538aa1e5d284b972195e4eb6 249 Gene3D G3DSA:3.30.460.10 4 117 4.4E-11 T 23-10-2018 TAM4_1932 49854682538aa1e5d284b972195e4eb6 249 SUPERFAMILY SSF81301 3 109 2.69E-10 T 23-10-2018 TAM4_2030 ece8120ec460613a7c0480516b05730a 252 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 14 246 35.582 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TAM4_2030 ece8120ec460613a7c0480516b05730a 252 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 20 237 2.0E-77 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TAM4_2030 ece8120ec460613a7c0480516b05730a 252 Gene3D G3DSA:3.20.20.390 3 250 5.8E-100 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily TAM4_2030 ece8120ec460613a7c0480516b05730a 252 SUPERFAMILY SSF51395 17 237 3.66E-47 T 23-10-2018 TAM4_2030 ece8120ec460613a7c0480516b05730a 252 Pfam PF01884 PcrB family 15 234 1.1E-66 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TAM4_2030 ece8120ec460613a7c0480516b05730a 252 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 227 7.8E-85 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 TAM4_1886 18fc53b04e36558d237ac2243be09830 460 SMART SM00382 54 185 3.1E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1886 18fc53b04e36558d237ac2243be09830 460 Gene3D G3DSA:3.40.50.300 36 190 1.0E-10 T 23-10-2018 TAM4_1886 18fc53b04e36558d237ac2243be09830 460 Pfam PF13173 AAA domain 55 188 5.6E-24 T 23-10-2018 TAM4_1886 18fc53b04e36558d237ac2243be09830 460 SUPERFAMILY SSF52540 40 234 4.24E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1886 18fc53b04e36558d237ac2243be09830 460 SUPERFAMILY SSF46785 281 328 5.99E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1828 e8e61e63e1d25c8e4fcfd897a6fc0d4f 393 Pfam PF07690 Major Facilitator Superfamily 18 201 3.4E-22 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1828 e8e61e63e1d25c8e4fcfd897a6fc0d4f 393 Pfam PF07690 Major Facilitator Superfamily 225 389 1.1E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1828 e8e61e63e1d25c8e4fcfd897a6fc0d4f 393 Gene3D G3DSA:1.20.1250.20 240 393 2.6E-22 T 23-10-2018 TAM4_1828 e8e61e63e1d25c8e4fcfd897a6fc0d4f 393 Gene3D G3DSA:1.20.1250.20 11 202 5.1E-25 T 23-10-2018 TAM4_1828 e8e61e63e1d25c8e4fcfd897a6fc0d4f 393 SUPERFAMILY SSF103473 1 391 1.7E-58 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1662 e2420477809c10689ade2442a97749bd 201 SUPERFAMILY SSF103039 62 182 1.12E-12 T 23-10-2018 IPR028976 CheC-like superfamily TAM4_1662 e2420477809c10689ade2442a97749bd 201 Gene3D G3DSA:3.40.1550.10 25 183 5.5E-11 T 23-10-2018 IPR028976 CheC-like superfamily TAM4_1444 b840573e19b0d411cebb6cf8c080be7e 225 Gene3D G3DSA:3.90.850.10 6 221 2.5E-89 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TAM4_1444 b840573e19b0d411cebb6cf8c080be7e 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 6.3E-70 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TAM4_1444 b840573e19b0d411cebb6cf8c080be7e 225 SUPERFAMILY SSF56529 13 221 8.24E-80 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TAM4_1376 8dde876ca8640d3884690a6f5a0f4cb3 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 4.0E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 SMART SM00790 4 207 6.6E-130 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 Gene3D G3DSA:1.10.599.10 240 601 7.4E-160 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 Gene3D G3DSA:1.10.569.10 242 427 7.4E-160 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 Gene3D G3DSA:3.60.9.10 1 211 5.4E-96 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 SUPERFAMILY SSF48310 211 604 1.44E-148 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 3.9E-82 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 601 2.1E-145 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TAM4_178 718a2a68da11ccd8ba3466a71d98db9d 605 SUPERFAMILY SSF56228 1 209 4.58E-79 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TAM4_460 c7ddce0c7abc86680f7ff4e65783bc53 215 Gene3D G3DSA:3.90.1490.10 117 213 2.4E-12 T 23-10-2018 TAM4_460 c7ddce0c7abc86680f7ff4e65783bc53 215 Pfam PF01902 Diphthamide synthase 1 209 3.5E-36 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_460 c7ddce0c7abc86680f7ff4e65783bc53 215 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 212 1.4E-34 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TAM4_460 c7ddce0c7abc86680f7ff4e65783bc53 215 SUPERFAMILY SSF52402 1 210 5.33E-52 T 23-10-2018 TAM4_460 c7ddce0c7abc86680f7ff4e65783bc53 215 Gene3D G3DSA:3.40.50.620 1 116 2.2E-14 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 3.7E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 Gene3D G3DSA:4.10.910.10 88 138 4.3E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 Gene3D G3DSA:1.10.8.50 1 76 9.3E-26 T 23-10-2018 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 5.3E-61 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 SUPERFAMILY SSF46946 9 148 1.18E-33 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 24.948 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_256 14ab1b5dc089fd8707ee5dc12fb62490 149 PIRSF PIRSF002134 1 149 3.2E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1472 e7f1709f305e377f6ef91db2e0008fd4 270 SUPERFAMILY SSF55729 1 132 6.32E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1472 e7f1709f305e377f6ef91db2e0008fd4 270 Pfam PF00583 Acetyltransferase (GNAT) family 25 124 1.3E-16 T 23-10-2018 IPR000182 GNAT domain TAM4_1472 e7f1709f305e377f6ef91db2e0008fd4 270 Gene3D G3DSA:3.40.630.30 1 188 1.8E-35 T 23-10-2018 TAM4_739 a50056b6bc08fa3211d03f1e5aad8389 221 Gene3D G3DSA:3.90.550.10 41 218 3.8E-11 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_739 a50056b6bc08fa3211d03f1e5aad8389 221 SUPERFAMILY SSF53448 27 155 2.22E-8 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_680 3cf88996b6fba63436a5f251e2f76d47 158 Pfam PF02915 Rubrerythrin 35 128 8.8E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_680 3cf88996b6fba63436a5f251e2f76d47 158 Gene3D G3DSA:1.20.1260.10 3 133 1.5E-12 T 23-10-2018 IPR012347 Ferritin-like TAM4_680 3cf88996b6fba63436a5f251e2f76d47 158 SUPERFAMILY SSF47240 7 135 1.7E-12 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1741 58022b69852822b30a10564d1d232e93 240 Gene3D G3DSA:3.40.50.150 12 210 1.1E-34 T 23-10-2018 TAM4_1741 58022b69852822b30a10564d1d232e93 240 SUPERFAMILY SSF53335 16 227 2.09E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1741 58022b69852822b30a10564d1d232e93 240 Pfam PF13649 Methyltransferase domain 50 144 5.0E-22 T 23-10-2018 TAM4_1513 902febcc6126b8cc55ef646d0610a1a4 84 Pfam PF04193 PQ loop repeat 4 55 4.4E-5 T 23-10-2018 IPR006603 PQ-loop repeat TAM4_1513 902febcc6126b8cc55ef646d0610a1a4 84 Gene3D G3DSA:1.20.1280.290 1 84 2.9E-10 T 23-10-2018 TAM4_895 856e0c4d63ef82ae608213057a09ca6b 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 124 9.629 T 23-10-2018 IPR022907 VapC family GO:0004540 TAM4_895 856e0c4d63ef82ae608213057a09ca6b 126 SUPERFAMILY SSF88723 1 122 4.49E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_895 856e0c4d63ef82ae608213057a09ca6b 126 Gene3D G3DSA:3.40.50.1010 1 122 2.8E-12 T 23-10-2018 TAM4_895 856e0c4d63ef82ae608213057a09ca6b 126 Pfam PF01850 PIN domain 2 117 5.8E-18 T 23-10-2018 IPR002716 PIN domain TAM4_866 41602d7034df4b765f524c6560a550a8 280 Gene3D G3DSA:3.80.30.30 52 255 8.7E-14 T 23-10-2018 TAM4_866 41602d7034df4b765f524c6560a550a8 280 SMART SM00729 19 226 1.4E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_866 41602d7034df4b765f524c6560a550a8 280 SUPERFAMILY SSF102114 11 219 2.09E-16 T 23-10-2018 TAM4_866 41602d7034df4b765f524c6560a550a8 280 Pfam PF04055 Radical SAM superfamily 24 188 6.1E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_589 a91f45dd11283ff2889c91ebbc1d6680 206 Gene3D G3DSA:1.20.58.2140 2 202 1.0E-64 T 23-10-2018 TAM4_589 a91f45dd11283ff2889c91ebbc1d6680 206 Pfam PF01997 Translin family 21 181 3.3E-11 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 TAM4_589 a91f45dd11283ff2889c91ebbc1d6680 206 SUPERFAMILY SSF74784 1 182 7.32E-39 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 SUPERFAMILY SSF103491 6 446 8.11E-110 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 PIRSF PIRSF004557 5 460 5.1E-102 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 424 442 8.7E-10 T 23-10-2018 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 8.7E-10 T 23-10-2018 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 144 169 8.7E-10 T 23-10-2018 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 170 193 8.7E-10 T 23-10-2018 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 Pfam PF10559 Plug domain of Sec61p 38 71 9.0E-9 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 ProSitePatterns PS00756 Protein secY signature 2. 163 180 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 Pfam PF00344 SecY translocase 72 439 6.2E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 Gene3D G3DSA:1.10.3370.10 26 461 1.4E-175 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 448 8.1E-90 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TAM4_183 8a1195a818aef00a87b9c5dfff6b822a 461 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 455 20.547 T 23-10-2018 IPR026593 Protein translocase subunit SecY TAM4_1941 44adf75b8062a822e71c0161716fd9df 286 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 204 1.9E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_1941 44adf75b8062a822e71c0161716fd9df 286 SUPERFAMILY SSF52518 18 272 4.42E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_1941 44adf75b8062a822e71c0161716fd9df 286 Gene3D G3DSA:3.40.50.970 67 260 1.4E-32 T 23-10-2018 TAM4_962 bcecd5faff4d0be2b275933f528ca289 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_962 bcecd5faff4d0be2b275933f528ca289 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.799 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal TAM4_962 bcecd5faff4d0be2b275933f528ca289 98 Pfam PF01157 Ribosomal protein L21e 6 96 1.0E-32 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_962 bcecd5faff4d0be2b275933f528ca289 98 SUPERFAMILY SSF50104 6 97 6.32E-32 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_962 bcecd5faff4d0be2b275933f528ca289 98 Gene3D G3DSA:2.30.30.70 2 97 1.0E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_627 88d913f1f174151fb4d2f7d6c8e4df92 353 PIRSF PIRSF002825 2 351 1.7E-62 T 23-10-2018 IPR026045 Ferric binding protein TAM4_627 88d913f1f174151fb4d2f7d6c8e4df92 353 Pfam PF13343 Bacterial extracellular solute-binding protein 96 339 2.3E-28 T 23-10-2018 TAM4_627 88d913f1f174151fb4d2f7d6c8e4df92 353 SUPERFAMILY SSF53850 43 343 7.95E-67 T 23-10-2018 TAM4_627 88d913f1f174151fb4d2f7d6c8e4df92 353 Gene3D G3DSA:3.40.190.10 48 321 4.4E-68 T 23-10-2018 TAM4_627 88d913f1f174151fb4d2f7d6c8e4df92 353 Gene3D G3DSA:3.40.190.10 148 336 4.4E-68 T 23-10-2018 TAM4_175 ce0c200952e485febc2f6fd68f64d0f1 389 SUPERFAMILY SSF103473 12 385 1.96E-44 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_175 ce0c200952e485febc2f6fd68f64d0f1 389 Gene3D G3DSA:1.20.1250.20 209 389 3.9E-16 T 23-10-2018 TAM4_175 ce0c200952e485febc2f6fd68f64d0f1 389 Pfam PF07690 Major Facilitator Superfamily 19 204 5.8E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_175 ce0c200952e485febc2f6fd68f64d0f1 389 Gene3D G3DSA:1.20.1250.20 11 202 2.0E-18 T 23-10-2018 TAM4_175 ce0c200952e485febc2f6fd68f64d0f1 389 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 250 285 3.1E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 218 226 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 145 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 SUPERFAMILY SSF63380 14 118 2.51E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Gene3D G3DSA:2.10.240.10 250 286 3.3E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Gene3D G3DSA:2.40.30.10 16 114 5.5E-20 T 23-10-2018 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Gene3D G3DSA:3.40.50.80 115 248 9.9E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Pfam PF00970 Oxidoreductase FAD-binding domain 36 113 6.2E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 PIRSF PIRSF006816 16 293 2.4E-81 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 SUPERFAMILY SSF52343 110 285 5.11E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_858 97806428dc2a66a344f9ebad6bbc979d 294 Pfam PF00175 Oxidoreductase NAD-binding domain 127 231 3.7E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 5.4E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 11 30 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 1.2E-16 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 SUPERFAMILY SSF55979 124 247 9.91E-31 T 23-10-2018 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 110 2.3E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 SUPERFAMILY SSF55979 3 117 4.35E-33 T 23-10-2018 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 3.1E-10 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 33.109 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TAM4_748 330d1da2570dbc2cb970ebbc57857cfb 249 Gene3D G3DSA:3.70.10.10 2 242 2.4E-79 T 23-10-2018 TAM4_1157 7b3bb2c15a18ffe3f74ff7ba87d2b222 666 Pfam PF01496 V-type ATPase 116kDa subunit family 561 651 3.5E-11 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1157 7b3bb2c15a18ffe3f74ff7ba87d2b222 666 Pfam PF01496 V-type ATPase 116kDa subunit family 152 435 4.4E-21 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1157 7b3bb2c15a18ffe3f74ff7ba87d2b222 666 Gene3D G3DSA:3.30.70.2750 149 224 2.1E-24 T 23-10-2018 TAM4_1157 7b3bb2c15a18ffe3f74ff7ba87d2b222 666 Gene3D G3DSA:3.30.70.2170 7 311 2.1E-24 T 23-10-2018 TAM4_1157 7b3bb2c15a18ffe3f74ff7ba87d2b222 666 Gene3D G3DSA:1.20.1460.20 47 290 2.1E-24 T 23-10-2018 TAM4_102 db524d007f1a857c804066de1f0d602a 333 SUPERFAMILY SSF51735 1 320 4.51E-94 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_102 db524d007f1a857c804066de1f0d602a 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 302 1.2E-82 T 23-10-2018 IPR016040 NAD(P)-binding domain TAM4_102 db524d007f1a857c804066de1f0d602a 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 4.3E-158 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TAM4_102 db524d007f1a857c804066de1f0d602a 333 Gene3D G3DSA:3.90.25.10 177 310 6.1E-131 T 23-10-2018 TAM4_102 db524d007f1a857c804066de1f0d602a 333 Gene3D G3DSA:3.40.50.720 4 294 6.1E-131 T 23-10-2018 TAM4_119 63d49dc821f0d32a118fa696ac1ddbb1 236 Pfam PF13367 Protease prsW family 31 203 5.3E-34 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Pfam PF08271 TFIIB zinc-binding 6 47 6.1E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Gene3D G3DSA:1.10.472.170 6 197 2.6E-67 T 23-10-2018 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Pfam PF00382 Transcription factor TFIIB repeat 212 282 7.5E-23 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Pfam PF00382 Transcription factor TFIIB repeat 117 186 7.3E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Gene3D G3DSA:1.10.472.10 207 300 3.8E-29 T 23-10-2018 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 SUPERFAMILY SSF57783 4 50 3.46E-17 T 23-10-2018 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 SUPERFAMILY SSF47954 206 298 2.18E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.865 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 2.7E-61 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 SUPERFAMILY SSF47954 108 199 5.35E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 SMART SM00385 114 195 2.0E-12 T 23-10-2018 IPR013763 Cyclin-like TAM4_2370 2d9d006eb80eb087db8fa58c8ebaebd8 300 SMART SM00385 210 291 4.1E-13 T 23-10-2018 IPR013763 Cyclin-like TAM4_1316 a7b432d035115a92349365efbd4ca014 293 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1316 a7b432d035115a92349365efbd4ca014 293 Pfam PF00005 ABC transporter 19 158 1.2E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1316 a7b432d035115a92349365efbd4ca014 293 SUPERFAMILY SSF52540 4 218 6.27E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1316 a7b432d035115a92349365efbd4ca014 293 SMART SM00382 28 214 2.0E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1316 a7b432d035115a92349365efbd4ca014 293 Gene3D G3DSA:3.40.50.300 3 268 1.7E-61 T 23-10-2018 TAM4_1270 f9097ca1b8f2c4361bf78938397bfa1c 347 Pfam PF04473 Transglutaminase-like domain 79 210 5.4E-28 T 23-10-2018 IPR007562 Transglutaminase-like domain TAM4_1270 f9097ca1b8f2c4361bf78938397bfa1c 347 SUPERFAMILY SSF54001 88 194 4.81E-5 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TAM4_819 93f3f70a96d48fd8c8c487797a9fdde3 354 Pfam PF13641 Glycosyltransferase like family 2 36 250 5.5E-36 T 23-10-2018 TAM4_819 93f3f70a96d48fd8c8c487797a9fdde3 354 SUPERFAMILY SSF53448 26 251 5.63E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_819 93f3f70a96d48fd8c8c487797a9fdde3 354 Gene3D G3DSA:3.90.550.10 24 240 3.9E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_648 519584f0795cf6f0c27c9bc73635c6e2 135 Pfam PF12838 4Fe-4S dicluster domain 12 60 2.7E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_648 519584f0795cf6f0c27c9bc73635c6e2 135 SUPERFAMILY SSF54862 8 88 3.28E-16 T 23-10-2018 TAM4_648 519584f0795cf6f0c27c9bc73635c6e2 135 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_648 519584f0795cf6f0c27c9bc73635c6e2 135 Gene3D G3DSA:3.30.70.20 7 63 7.0E-14 T 23-10-2018 TAM4_1912 54c2765bf34076c1ca34e6eca635afdb 316 Pfam PF01637 ATPase domain predominantly from Archaea 4 195 1.2E-27 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1912 54c2765bf34076c1ca34e6eca635afdb 316 Gene3D G3DSA:3.40.50.300 58 160 1.0E-15 T 23-10-2018 TAM4_1912 54c2765bf34076c1ca34e6eca635afdb 316 SUPERFAMILY SSF52540 3 232 2.33E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1912 54c2765bf34076c1ca34e6eca635afdb 316 SUPERFAMILY SSF46785 229 309 2.4E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1334 ed404f1df4ed66ed654897bf1a54b76a 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 TAM4_529 18b1baadacfd9e7c5011e5c0d3d964b6 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.84 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 TAM4_529 18b1baadacfd9e7c5011e5c0d3d964b6 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_529 18b1baadacfd9e7c5011e5c0d3d964b6 200 Pfam PF01015 Ribosomal S3Ae family 11 198 6.3E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_529 18b1baadacfd9e7c5011e5c0d3d964b6 200 SMART SM01397 8 198 2.8E-99 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_676 f8f7310f224c439c5408d5846ed43d62 330 Pfam PF02374 Anion-transporting ATPase 12 326 8.1E-72 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TAM4_676 f8f7310f224c439c5408d5846ed43d62 330 Gene3D G3DSA:3.40.50.300 3 330 1.7E-88 T 23-10-2018 TAM4_676 f8f7310f224c439c5408d5846ed43d62 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 1.3E-72 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 TAM4_676 f8f7310f224c439c5408d5846ed43d62 330 SUPERFAMILY SSF52540 11 321 7.66E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2031 6ae03b3e98e93b016dd204aa23cd3973 155 Pfam PF03551 Transcriptional regulator PadR-like family 18 91 5.1E-17 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TAM4_2031 6ae03b3e98e93b016dd204aa23cd3973 155 SUPERFAMILY SSF46785 4 96 6.0E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_2031 6ae03b3e98e93b016dd204aa23cd3973 155 Gene3D G3DSA:1.10.10.10 7 117 3.8E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1413 a19a2c974ef0835c38060a7b7c9a5ab6 163 Gene3D G3DSA:1.20.120.610 2 157 2.1E-39 T 23-10-2018 TAM4_1413 a19a2c974ef0835c38060a7b7c9a5ab6 163 SUPERFAMILY SSF81333 6 70 4.05E-11 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TAM4_1413 a19a2c974ef0835c38060a7b7c9a5ab6 163 SUPERFAMILY SSF81333 88 155 9.68E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TAM4_1413 a19a2c974ef0835c38060a7b7c9a5ab6 163 Pfam PF00137 ATP synthase subunit C 9 68 1.7E-13 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TAM4_1413 a19a2c974ef0835c38060a7b7c9a5ab6 163 Pfam PF00137 ATP synthase subunit C 96 154 2.9E-15 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TAM4_2072 9fde16382eb4298afaca7a3b3887c5f9 253 SUPERFAMILY SSF102114 30 213 8.5E-14 T 23-10-2018 TAM4_2072 9fde16382eb4298afaca7a3b3887c5f9 253 Pfam PF04055 Radical SAM superfamily 32 188 8.7E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_2072 9fde16382eb4298afaca7a3b3887c5f9 253 Gene3D G3DSA:3.20.20.70 4 253 4.5E-27 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_2072 9fde16382eb4298afaca7a3b3887c5f9 253 Pfam PF13353 4Fe-4S single cluster domain 29 136 8.7E-8 T 23-10-2018 TAM4_2072 9fde16382eb4298afaca7a3b3887c5f9 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 39.048 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TAM4_2075 908623c87d773902cd87d4e4e9bf0b70 181 SUPERFAMILY SSF52218 1 167 4.05E-33 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_2075 908623c87d773902cd87d4e4e9bf0b70 181 Gene3D G3DSA:3.40.50.360 1 180 6.8E-38 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_2075 908623c87d773902cd87d4e4e9bf0b70 181 Pfam PF03358 NADPH-dependent FMN reductase 1 130 1.1E-27 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TAM4_2177 c5802261af5a01eb7b463be0e51113f9 139 Pfam PF07849 Protein of unknown function (DUF1641) 99 133 7.9E-12 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 TAM4_151 0ca048b3e701762cd76d2fc4f3d6f5c1 292 Pfam PF00483 Nucleotidyl transferase 5 257 5.9E-32 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_151 0ca048b3e701762cd76d2fc4f3d6f5c1 292 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 261 1.0E-112 T 23-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 TAM4_151 0ca048b3e701762cd76d2fc4f3d6f5c1 292 Gene3D G3DSA:3.90.550.10 1 289 1.2E-91 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_151 0ca048b3e701762cd76d2fc4f3d6f5c1 292 SUPERFAMILY SSF53448 4 269 6.44E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 SUPERFAMILY SSF117892 53 186 5.36E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.6E-39 T 23-10-2018 IPR001107 Band 7 domain TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 Gene3D G3DSA:3.30.479.30 50 181 7.5E-52 T 23-10-2018 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 111 128 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 29 51 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 131 154 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 199 222 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 155 173 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 76 97 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 PRINTS PR00721 Stomatin signature 174 195 2.0E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TAM4_9 3b041d1940c5f8f36922d7c26ab086fc 267 SMART SM00244 22 179 2.7E-70 T 23-10-2018 IPR001107 Band 7 domain TAM4_1601 8a2aef02c8192e7261bba12d8a941c03 124 Pfam PF01909 Nucleotidyltransferase domain 9 67 2.8E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1601 8a2aef02c8192e7261bba12d8a941c03 124 Gene3D G3DSA:3.30.460.10 2 117 4.6E-14 T 23-10-2018 TAM4_1601 8a2aef02c8192e7261bba12d8a941c03 124 SUPERFAMILY SSF81301 3 95 1.43E-17 T 23-10-2018 TAM4_2027 c7f66590460c8f6b53d9bf6f9e7760e0 158 Pfam PF02915 Rubrerythrin 5 137 1.6E-15 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2027 c7f66590460c8f6b53d9bf6f9e7760e0 158 SUPERFAMILY SSF47240 1 146 5.5E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_2027 c7f66590460c8f6b53d9bf6f9e7760e0 158 Gene3D G3DSA:1.20.1260.10 1 142 9.8E-27 T 23-10-2018 IPR012347 Ferritin-like TAM4_1575 b6978468bdd271a060fc7c6b5bb5668a 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 20.884 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1575 b6978468bdd271a060fc7c6b5bb5668a 77 Gene3D G3DSA:3.10.20.10 3 76 2.1E-28 T 23-10-2018 TAM4_1575 b6978468bdd271a060fc7c6b5bb5668a 77 SUPERFAMILY SSF160374 1 73 6.8E-25 T 23-10-2018 TAM4_1575 b6978468bdd271a060fc7c6b5bb5668a 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 51 5.0E-14 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 TAM4_1575 b6978468bdd271a060fc7c6b5bb5668a 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 4.4E-12 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1553 c778a48b859de595bd6be6aa769b64e4 240 Pfam PF01904 Protein of unknown function DUF72 14 234 2.7E-38 T 23-10-2018 IPR002763 Protein of unknown function DUF72 TAM4_1553 c778a48b859de595bd6be6aa769b64e4 240 Gene3D G3DSA:3.20.20.410 1 238 2.9E-41 T 23-10-2018 IPR036520 UPF0759 superfamily TAM4_1553 c778a48b859de595bd6be6aa769b64e4 240 SUPERFAMILY SSF117396 1 238 1.11E-47 T 23-10-2018 IPR036520 UPF0759 superfamily TAM4_634 dc6516219197df4aad959ad1ce82fc85 398 Pfam PF01979 Amidohydrolase family 50 393 3.0E-59 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TAM4_634 dc6516219197df4aad959ad1ce82fc85 398 Gene3D G3DSA:2.30.40.10 12 395 1.8E-116 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TAM4_634 dc6516219197df4aad959ad1ce82fc85 398 Gene3D G3DSA:3.20.20.140 54 339 1.8E-116 T 23-10-2018 TAM4_634 dc6516219197df4aad959ad1ce82fc85 398 SUPERFAMILY SSF51556 53 342 1.04E-83 T 23-10-2018 IPR032466 Metal-dependent hydrolase TAM4_634 dc6516219197df4aad959ad1ce82fc85 398 SUPERFAMILY SSF51338 12 395 8.65E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TAM4_519 a9a4582e2330a6534f6c0af7bf6aa277 385 Pfam PF13173 AAA domain 44 175 4.7E-23 T 23-10-2018 TAM4_519 a9a4582e2330a6534f6c0af7bf6aa277 385 Gene3D G3DSA:3.40.50.300 33 142 4.1E-5 T 23-10-2018 TAM4_519 a9a4582e2330a6534f6c0af7bf6aa277 385 SUPERFAMILY SSF52540 39 209 1.52E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_336 f5a41ebb86b82d0869cc940574139c82 416 Pfam PF04894 Archaeal Nre, N-terminal 19 284 1.1E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal TAM4_336 f5a41ebb86b82d0869cc940574139c82 416 Hamap MF_02096 DNA repair protein. 1 406 40.299 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 TAM4_336 f5a41ebb86b82d0869cc940574139c82 416 Pfam PF04895 Archaeal Nre, C-terminal 296 406 3.2E-38 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal TAM4_2386 0150fd839f54f6e9832325ce6956bb0c 108 Pfam PF03966 Trm112p-like protein 2 55 1.3E-4 T 23-10-2018 IPR005651 Trm112-like TAM4_2386 0150fd839f54f6e9832325ce6956bb0c 108 Gene3D G3DSA:1.10.10.1220 1 88 1.3E-53 T 23-10-2018 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 SUPERFAMILY SSF57802 2 53 3.7E-25 T 23-10-2018 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 Gene3D G3DSA:2.20.28.10 2 53 5.4E-30 T 23-10-2018 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 PRINTS PR00163 Rubredoxin signature 3 19 3.3E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 PRINTS PR00163 Rubredoxin signature 33 49 3.3E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 Pfam PF00301 Rubredoxin 3 49 1.1E-25 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 PIRSF PIRSF000071 1 53 4.4E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 TAM4_2042 a696af39c14a7b16e10d0d7e6c738a6f 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TAM4_609 72bb5e39af55ed8bc2653015cb5149d2 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.7E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TAM4_609 72bb5e39af55ed8bc2653015cb5149d2 80 SUPERFAMILY SSF54909 2 76 5.09E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TAM4_609 72bb5e39af55ed8bc2653015cb5149d2 80 Gene3D G3DSA:3.30.70.920 2 74 2.3E-20 T 23-10-2018 TAM4_440 3214ae5cd6c2e2e9d20690665feba08d 124 Gene3D G3DSA:3.40.140.10 3 124 3.9E-26 T 23-10-2018 TAM4_440 3214ae5cd6c2e2e9d20690665feba08d 124 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 102 1.8E-8 T 23-10-2018 IPR028090 JAB domain, prokaryotic TAM4_440 3214ae5cd6c2e2e9d20690665feba08d 124 SUPERFAMILY SSF102712 5 122 5.62E-28 T 23-10-2018 TAM4_1422 7e16da1d5fc21362f84b804900d5a1f0 183 Gene3D G3DSA:3.40.220.10 1 182 4.4E-54 T 23-10-2018 TAM4_1422 7e16da1d5fc21362f84b804900d5a1f0 183 SMART SM00506 2 145 3.2E-50 T 23-10-2018 IPR002589 Macro domain TAM4_1422 7e16da1d5fc21362f84b804900d5a1f0 183 Pfam PF01661 Macro domain 19 144 7.7E-35 T 23-10-2018 IPR002589 Macro domain TAM4_1422 7e16da1d5fc21362f84b804900d5a1f0 183 SUPERFAMILY SSF52949 2 179 2.02E-51 T 23-10-2018 TAM4_1582 6301171daf599c47e264801c07c35c77 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.295 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TAM4_1582 6301171daf599c47e264801c07c35c77 533 Gene3D G3DSA:3.40.50.300 1 283 1.3E-139 T 23-10-2018 TAM4_1582 6301171daf599c47e264801c07c35c77 533 SUPERFAMILY SSF52317 287 529 3.67E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1582 6301171daf599c47e264801c07c35c77 533 Gene3D G3DSA:3.40.50.880 284 533 2.9E-107 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1582 6301171daf599c47e264801c07c35c77 533 Pfam PF06418 CTP synthase N-terminus 3 265 1.3E-127 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TAM4_1582 6301171daf599c47e264801c07c35c77 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 6.9E-57 T 23-10-2018 IPR017926 Glutamine amidotransferase TAM4_1582 6301171daf599c47e264801c07c35c77 533 SUPERFAMILY SSF52540 2 265 1.29E-121 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1582 6301171daf599c47e264801c07c35c77 533 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 7.1E-254 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TAM4_1136 fe1c8919c04d10171e60fe482e238099 430 Pfam PF13173 AAA domain 43 160 1.3E-24 T 23-10-2018 TAM4_1136 fe1c8919c04d10171e60fe482e238099 430 Pfam PF13635 Domain of unknown function (DUF4143) 213 362 3.9E-15 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1136 fe1c8919c04d10171e60fe482e238099 430 SUPERFAMILY SSF52540 30 234 1.08E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 1.3E-87 T 23-10-2018 IPR011903 Glutaredoxin-like domain TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 SUPERFAMILY SSF52833 5 116 1.97E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 Gene3D G3DSA:3.40.30.10 121 225 3.5E-26 T 23-10-2018 TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 SUPERFAMILY SSF52833 121 223 3.25E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 Pfam PF00085 Thioredoxin 13 92 6.7E-5 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 Pfam PF13192 Thioredoxin domain 137 222 1.2E-14 T 23-10-2018 IPR012336 Thioredoxin-like fold TAM4_1905 c3ac69201ac5fef2b0e0785569128227 226 Gene3D G3DSA:3.40.30.10 1 116 2.4E-37 T 23-10-2018 TAM4_2038 193a60aebb4ba84094913214a72c5a1e 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 4.3E-8 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TAM4_1759 687f4f2b76c043ea84358679e91a1f6c 310 Gene3D G3DSA:3.20.20.70 16 240 3.0E-24 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1759 687f4f2b76c043ea84358679e91a1f6c 310 SMART SM00729 24 237 1.0E-18 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_1759 687f4f2b76c043ea84358679e91a1f6c 310 SUPERFAMILY SSF102114 15 281 2.88E-40 T 23-10-2018 TAM4_1759 687f4f2b76c043ea84358679e91a1f6c 310 Pfam PF04055 Radical SAM superfamily 36 193 1.6E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 SUPERFAMILY SSF54862 3 61 8.38E-15 T 23-10-2018 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 Gene3D G3DSA:3.30.70.20 2 63 2.3E-21 T 23-10-2018 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 58 7.9E-16 T 23-10-2018 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.6E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.6E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TAM4_1091 b3c0c7d257ab55249d5fc606163b19f7 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 2.6E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TAM4_2183 199f8edf3fc77bfb68284a46c1973a62 312 SUPERFAMILY SSF81345 5 306 1.22E-69 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_2183 199f8edf3fc77bfb68284a46c1973a62 312 Pfam PF01032 FecCD transport family 12 306 1.3E-78 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TAM4_2183 199f8edf3fc77bfb68284a46c1973a62 312 Gene3D G3DSA:1.10.3470.10 2 310 4.1E-86 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_464 45fd9874740f04e63261a83efada32b0 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 5.7E-46 T 23-10-2018 IPR015207 Protein of unknown function DUF1931 TAM4_464 45fd9874740f04e63261a83efada32b0 153 SUPERFAMILY SSF47113 1 153 2.32E-52 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_464 45fd9874740f04e63261a83efada32b0 153 Gene3D G3DSA:1.10.20.10 5 153 8.2E-37 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 1.3E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 292 2.4E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 SMART SM00849 19 207 0.0018 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 Gene3D G3DSA:3.60.15.10 1 299 2.1E-83 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.708 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 SUPERFAMILY SSF56281 3 297 2.51E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_2092 c0dc977d6d2f539cee4f26c197604de9 314 Pfam PF00753 Metallo-beta-lactamase superfamily 18 76 3.0E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_2437 6f672b15a1856738bab6a92259804852 88 SUPERFAMILY SSF54285 1 86 3.36E-24 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TAM4_2437 6f672b15a1856738bab6a92259804852 88 Pfam PF02597 ThiS family 5 88 5.0E-22 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TAM4_2437 6f672b15a1856738bab6a92259804852 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.9E-28 T 23-10-2018 IPR010038 MoaD, archaeal-type TAM4_2437 6f672b15a1856738bab6a92259804852 88 Gene3D G3DSA:3.10.20.30 1 88 9.0E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TAM4_1454 cfafea9102fb00f0eb4a72be261b4317 71 Gene3D G3DSA:2.40.50.140 7 71 4.2E-26 T 23-10-2018 TAM4_1454 cfafea9102fb00f0eb4a72be261b4317 71 SUPERFAMILY SSF50249 10 71 2.23E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1454 cfafea9102fb00f0eb4a72be261b4317 71 Pfam PF01938 TRAM domain 15 71 3.2E-15 T 23-10-2018 IPR002792 TRAM domain TAM4_976 57dab4b898331ba37cc65019163fbf28 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PIRSF PIRSF000097 6 123 9.2E-17 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PIRSF PIRSF000097 121 273 2.3E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 SUPERFAMILY SSF51430 14 269 3.01E-77 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TAM4_976 57dab4b898331ba37cc65019163fbf28 275 Pfam PF00248 Aldo/keto reductase family 18 273 5.5E-63 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PRINTS PR00069 Aldo-keto reductase signature 102 120 2.5E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PRINTS PR00069 Aldo-keto reductase signature 209 233 2.5E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PRINTS PR00069 Aldo-keto reductase signature 134 151 2.5E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 PRINTS PR00069 Aldo-keto reductase signature 46 70 2.5E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TAM4_976 57dab4b898331ba37cc65019163fbf28 275 Gene3D G3DSA:3.20.20.100 11 273 4.1E-88 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 28.29 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 Pfam PF00276 Ribosomal protein L23 5 72 5.6E-20 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.873 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 Gene3D G3DSA:3.30.70.330 1 86 8.1E-37 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 1.2E-39 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_208 9c89d6650ce164b0ad568c1cdc7996c8 86 SUPERFAMILY SSF54189 1 80 3.6E-28 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TAM4_1071 1d1238d4fdfb063e1286e07e223591fb 293 Pfam PF00146 NADH dehydrogenase 8 290 1.5E-52 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1071 1d1238d4fdfb063e1286e07e223591fb 293 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 188 201 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_548 c4f9a71d4f7679ccd8531022b87c1c56 285 TIGRFAM TIGR01230 agmatinase: agmatinase 20 281 1.8E-69 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TAM4_548 c4f9a71d4f7679ccd8531022b87c1c56 285 PIRSF PIRSF036979 2 285 1.4E-84 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TAM4_548 c4f9a71d4f7679ccd8531022b87c1c56 285 Pfam PF00491 Arginase family 22 279 3.9E-63 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TAM4_548 c4f9a71d4f7679ccd8531022b87c1c56 285 Gene3D G3DSA:3.40.800.10 6 285 6.5E-78 T 23-10-2018 TAM4_548 c4f9a71d4f7679ccd8531022b87c1c56 285 SUPERFAMILY SSF52768 16 283 1.19E-73 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TAM4_1885 c6bd16cbc76cb956694d65140ddd02c2 359 SUPERFAMILY SSF109604 1 344 1.0E-80 T 23-10-2018 TAM4_1885 c6bd16cbc76cb956694d65140ddd02c2 359 SMART SM00471 46 156 3.9E-13 T 23-10-2018 IPR003607 HD/PDEase domain TAM4_1885 c6bd16cbc76cb956694d65140ddd02c2 359 Pfam PF01966 HD domain 50 108 7.4E-9 T 23-10-2018 IPR006674 HD domain TAM4_1885 c6bd16cbc76cb956694d65140ddd02c2 359 Gene3D G3DSA:1.10.3210.10 1 257 2.0E-70 T 23-10-2018 TAM4_846 9f980b6b4cbb5abe7d95862cd34685da 199 Hamap MF_01078 UPF0278 protein . 1 193 30.415 T 23-10-2018 IPR014856 PIN-domain ribonuclease TAM4_846 9f980b6b4cbb5abe7d95862cd34685da 199 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 3.0E-71 T 23-10-2018 IPR014856 PIN-domain ribonuclease TAM4_846 9f980b6b4cbb5abe7d95862cd34685da 199 SUPERFAMILY SSF88723 75 192 3.36E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_846 9f980b6b4cbb5abe7d95862cd34685da 199 Pfam PF08745 PINc domain ribonuclease 2 190 1.4E-67 T 23-10-2018 IPR014856 PIN-domain ribonuclease TAM4_1969 3856cbe95819e38a8e36343deac00b50 393 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 296 1.2E-66 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TAM4_1969 3856cbe95819e38a8e36343deac00b50 393 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 7 391 2.0E-82 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap TAM4_1969 3856cbe95819e38a8e36343deac00b50 393 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 316 5.2E-69 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TAM4_2148 8399463d08de1f6cb0b393abac99321a 87 SUPERFAMILY SSF143011 1 82 5.49E-27 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_2148 8399463d08de1f6cb0b393abac99321a 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 83 1.2E-11 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TAM4_2148 8399463d08de1f6cb0b393abac99321a 87 Gene3D G3DSA:3.30.2310.20 1 84 2.0E-25 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_809 d355badf653054446a72f49576e0e046 156 Gene3D G3DSA:3.40.50.1450 12 155 2.6E-17 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_809 d355badf653054446a72f49576e0e046 156 SUPERFAMILY SSF53163 15 146 4.71E-10 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_2469 de30d8b107981cc69fd0f25d8ec395b1 84 Gene3D G3DSA:2.10.260.10 2 48 1.7E-13 T 23-10-2018 TAM4_2469 de30d8b107981cc69fd0f25d8ec395b1 84 SMART SM00966 4 48 4.2E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2469 de30d8b107981cc69fd0f25d8ec395b1 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 43 1.1E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2469 de30d8b107981cc69fd0f25d8ec395b1 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 3.2E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_2469 de30d8b107981cc69fd0f25d8ec395b1 84 SUPERFAMILY SSF89447 3 44 1.44E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_1546 1da0843d3d1b53c39327d936b58cbc82 513 SUPERFAMILY SSF51717 158 382 2.35E-22 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TAM4_1546 1da0843d3d1b53c39327d936b58cbc82 513 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 500 1.3E-96 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein TAM4_681 057b5db58be10bbacd8b2115497fa128 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 9.1E-8 T 23-10-2018 TAM4_681 057b5db58be10bbacd8b2115497fa128 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 9.1E-8 T 23-10-2018 TAM4_681 057b5db58be10bbacd8b2115497fa128 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 9.1E-8 T 23-10-2018 TAM4_681 057b5db58be10bbacd8b2115497fa128 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 9.1E-8 T 23-10-2018 TAM4_681 057b5db58be10bbacd8b2115497fa128 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 9.1E-8 T 23-10-2018 TAM4_681 057b5db58be10bbacd8b2115497fa128 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 1.4E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_156 ee2fce3bcfcfc7dce4b944cb2532a0cf 311 SUPERFAMILY SSF53686 3 288 1.44E-79 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TAM4_156 ee2fce3bcfcfc7dce4b944cb2532a0cf 311 Gene3D G3DSA:3.40.50.1100 26 121 7.3E-96 T 23-10-2018 TAM4_156 ee2fce3bcfcfc7dce4b944cb2532a0cf 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 284 4.4E-66 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TAM4_156 ee2fce3bcfcfc7dce4b944cb2532a0cf 311 Gene3D G3DSA:3.40.50.1100 4 289 7.3E-96 T 23-10-2018 TAM4_156 ee2fce3bcfcfc7dce4b944cb2532a0cf 311 TIGRFAM TIGR00260 thrC: threonine synthase 10 287 2.2E-52 T 23-10-2018 IPR004450 Threonine synthase-like TAM4_1681 70e2d5c3ad8d00f50f40180f7514c77c 423 Gene3D G3DSA:3.40.50.300 4 72 2.0E-5 T 23-10-2018 TAM4_1681 70e2d5c3ad8d00f50f40180f7514c77c 423 Pfam PF13173 AAA domain 34 161 1.7E-31 T 23-10-2018 TAM4_1681 70e2d5c3ad8d00f50f40180f7514c77c 423 Pfam PF13635 Domain of unknown function (DUF4143) 217 367 1.1E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1681 70e2d5c3ad8d00f50f40180f7514c77c 423 SUPERFAMILY SSF52540 13 196 1.45E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1185 54bd932b916abc7f061bb2ffe056019f 67 SUPERFAMILY SSF141004 11 67 2.35E-8 T 23-10-2018 TAM4_1087 1aa86562494e8169033b889487c45ea4 187 Gene3D G3DSA:3.40.50.12280 1 153 9.0E-42 T 23-10-2018 TAM4_1087 1aa86562494e8169033b889487c45ea4 187 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 135 2.1E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1087 1aa86562494e8169033b889487c45ea4 187 SUPERFAMILY SSF56770 4 152 8.11E-42 T 23-10-2018 TAM4_1877 fde4d2ddea19d6d532e7a0bea3f5371e 145 Pfam PF01986 Domain of unknown function DUF123 24 110 5.4E-22 T 23-10-2018 IPR002837 Protein of unknown function DUF123 TAM4_1877 fde4d2ddea19d6d532e7a0bea3f5371e 145 SMART SM00465 12 113 5.4E-7 T 23-10-2018 IPR000305 GIY-YIG endonuclease TAM4_843 9402b26d59740409eb4054b02f0576d5 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 207 2.6E-60 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TAM4_843 9402b26d59740409eb4054b02f0576d5 213 Pfam PF01914 MarC family integral membrane protein 6 211 4.8E-60 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TAM4_360 f1ed5316e25663880315c5363b6d5446 137 Pfam PF00892 EamA-like transporter family 4 136 3.2E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_360 f1ed5316e25663880315c5363b6d5446 137 SUPERFAMILY SSF103481 38 136 1.57E-10 T 23-10-2018 TAM4_1223 76d7d838d0f978b5d08ac3fd278cc8e6 258 Pfam PF05763 Protein of unknown function (DUF835) 134 255 9.7E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 PIRSF PIRSF005644 2 328 9.5E-62 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 141 5.7E-12 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 153 305 2.3E-15 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 SUPERFAMILY SSF55326 5 146 6.28E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 SUPERFAMILY SSF56042 152 312 1.2E-25 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 Gene3D G3DSA:3.30.1330.10 3 145 2.4E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TAM4_2163 91eba2b3bcbdc5dbfa079ea8854e89b2 331 Gene3D G3DSA:3.90.650.10 151 325 3.1E-31 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TAM4_1358 887249dfb36813ba9b95b85f4c62dc58 246 Gene3D G3DSA:3.20.20.70 4 182 2.7E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1358 887249dfb36813ba9b95b85f4c62dc58 246 Pfam PF04055 Radical SAM superfamily 26 169 4.1E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_1358 887249dfb36813ba9b95b85f4c62dc58 246 Pfam PF13353 4Fe-4S single cluster domain 18 93 1.1E-8 T 23-10-2018 TAM4_1358 887249dfb36813ba9b95b85f4c62dc58 246 SUPERFAMILY SSF102114 26 169 4.84E-19 T 23-10-2018 TAM4_1358 887249dfb36813ba9b95b85f4c62dc58 246 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 4 191 5.6E-52 T 23-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein TAM4_597 a84c86beaeadf272b03b90975646e88a 310 Gene3D G3DSA:1.10.3720.10 94 309 1.1E-22 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_597 a84c86beaeadf272b03b90975646e88a 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 309 3.9E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_597 a84c86beaeadf272b03b90975646e88a 310 SUPERFAMILY SSF161098 99 289 2.22E-23 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_522 24fe80d52193c0d9c43caa958abda274 213 PIRSF PIRSF019202 1 213 5.8E-50 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TAM4_522 24fe80d52193c0d9c43caa958abda274 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 4.1E-28 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TAM4_1654 23b824aec80e3d9a9a8bb045e37692dd 409 Pfam PF12698 ABC-2 family transporter protein 24 398 5.8E-35 T 23-10-2018 TAM4_2107 9109ac6d94a55db2753e007c211c8895 94 SUPERFAMILY SSF50346 4 79 1.44E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TAM4_2107 9109ac6d94a55db2753e007c211c8895 94 Pfam PF05239 PRC-barrel domain 1 82 1.3E-13 T 23-10-2018 IPR027275 PRC-barrel domain TAM4_2107 9109ac6d94a55db2753e007c211c8895 94 Gene3D G3DSA:2.30.30.240 3 81 6.4E-5 T 23-10-2018 TAM4_271 d4596ff6e6c8e0bfd21ac0c783cbc374 150 Pfam PF05763 Protein of unknown function (DUF835) 41 147 1.6E-23 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_864 c5aef88d65ef8cbdf9282cfc527ee859 132 Pfam PF03334 Na+/H+ antiporter subunit 11 95 6.6E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_864 c5aef88d65ef8cbdf9282cfc527ee859 132 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 3.9E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 PRINTS PR00446 Hydrogen uptake protein signature 51 61 1.8E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 PRINTS PR00446 Hydrogen uptake protein signature 15 26 1.8E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 PRINTS PR00446 Hydrogen uptake protein signature 63 79 1.8E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 PRINTS PR00446 Hydrogen uptake protein signature 3 15 1.8E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 Gene3D G3DSA:3.40.50.1450 1 147 1.6E-34 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 SUPERFAMILY SSF53163 2 146 9.42E-30 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 1.4E-31 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_478 984b2f47b3d65f30e5f48c51a4444374 147 Pfam PF01750 Hydrogenase maturation protease 27 145 1.9E-22 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TAM4_1252 94e488cb3803a2d9b137f4f83e4fb7ca 169 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 1 156 2.3E-30 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 TAM4_1252 94e488cb3803a2d9b137f4f83e4fb7ca 169 SUPERFAMILY SSF56399 1 167 2.66E-55 T 23-10-2018 TAM4_1252 94e488cb3803a2d9b137f4f83e4fb7ca 169 Gene3D G3DSA:3.20.170.30 84 169 1.5E-29 T 23-10-2018 TAM4_1252 94e488cb3803a2d9b137f4f83e4fb7ca 169 Gene3D G3DSA:1.10.10.970 1 64 7.3E-20 T 23-10-2018 TAM4_1252 94e488cb3803a2d9b137f4f83e4fb7ca 169 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 1 165 30.158 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 Pfam PF00361 Proton-conducting membrane transporter 137 424 1.2E-43 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 4.9E-25 T 23-10-2018 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 4.9E-25 T 23-10-2018 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 4.9E-25 T 23-10-2018 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 4.9E-25 T 23-10-2018 TAM4_1922 1e8c8f26e5dc2441a016da99a051ab09 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 4.9E-25 T 23-10-2018 TAM4_1730 11b3750788994f72e312320b6043a2d9 377 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 377 8.1E-8 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1372 7e805c07b5d9df67ef4d5c4f503f75a8 46 Gene3D G3DSA:3.30.160.250 19 46 2.0E-6 T 23-10-2018 TAM4_1372 7e805c07b5d9df67ef4d5c4f503f75a8 46 SUPERFAMILY SSF143100 10 45 3.66E-7 T 23-10-2018 IPR035069 TTHA1013/TTHA0281-like TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 Gene3D G3DSA:1.20.1270.30 70 243 6.1E-72 T 23-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 Gene3D G3DSA:3.40.50.2030 244 411 1.3E-70 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 SUPERFAMILY SSF56821 11 630 3.01E-209 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 17 629 3.1E-236 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 Pfam PF03063 Prismane/CO dehydrogenase family 53 610 9.9E-176 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 PIRSF PIRSF005023 6 631 2.0E-262 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TAM4_1067 0a6cd8ddf73d1b890d55d2a4e1e69d98 632 Gene3D G3DSA:3.40.50.2030 414 627 1.3E-93 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TAM4_880 c279612585130a60f9fdbdeff37cb3d4 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 14 197 5.6E-9 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TAM4_880 c279612585130a60f9fdbdeff37cb3d4 212 Gene3D G3DSA:3.40.50.11570 4 207 6.5E-11 T 23-10-2018 TAM4_2089 47f66d69d0adf322b3d9ec727d45b892 251 Pfam PF00005 ABC transporter 18 161 4.9E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_2089 47f66d69d0adf322b3d9ec727d45b892 251 SUPERFAMILY SSF52540 3 226 5.73E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_2089 47f66d69d0adf322b3d9ec727d45b892 251 Gene3D G3DSA:3.40.50.300 1 243 7.7E-70 T 23-10-2018 TAM4_2089 47f66d69d0adf322b3d9ec727d45b892 251 SMART SM00382 27 219 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Pfam PF03129 Anticodon binding domain 340 429 1.5E-18 T 23-10-2018 IPR004154 Anticodon-binding TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Gene3D G3DSA:3.40.50.800 337 431 5.9E-25 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 15 382 26.456 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Pfam PF13393 Histidyl-tRNA synthetase 8 322 1.4E-65 T 23-10-2018 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 SUPERFAMILY SSF55681 4 332 2.59E-88 T 23-10-2018 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Gene3D G3DSA:3.30.930.10 1 327 6.3E-111 T 23-10-2018 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 PIRSF PIRSF001549 1 431 1.7E-141 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 421 1.8E-128 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 10 325 2.2E-86 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 SUPERFAMILY SSF52954 339 433 1.06E-22 T 23-10-2018 TAM4_1318 abcce864d0f5f5ebc6ac57f1e1d3b05f 435 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 431 31.299 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TAM4_758 37ba0b7034b5a79a38adda30d4448ca2 441 Pfam PF01523 Putative modulator of DNA gyrase 14 304 1.8E-47 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_758 37ba0b7034b5a79a38adda30d4448ca2 441 Gene3D G3DSA:3.30.2290.10 1 206 7.7E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_758 37ba0b7034b5a79a38adda30d4448ca2 441 SUPERFAMILY SSF111283 2 439 7.19E-98 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_327 830c3f0ec7fab51ee5dbc76f50e741c4 239 Pfam PF00005 ABC transporter 17 154 8.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_327 830c3f0ec7fab51ee5dbc76f50e741c4 239 Gene3D G3DSA:3.40.50.300 4 235 1.2E-62 T 23-10-2018 TAM4_327 830c3f0ec7fab51ee5dbc76f50e741c4 239 SUPERFAMILY SSF52540 6 211 1.67E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_327 830c3f0ec7fab51ee5dbc76f50e741c4 239 SMART SM00382 26 201 2.0E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_247 392558af90149e7b98e1bb0709db82cc 153 Gene3D G3DSA:3.30.54.20 79 121 3.1E-24 T 23-10-2018 TAM4_247 392558af90149e7b98e1bb0709db82cc 153 Gene3D G3DSA:3.30.980.10 4 78 1.1E-33 T 23-10-2018 TAM4_247 392558af90149e7b98e1bb0709db82cc 153 SUPERFAMILY SSF55186 6 151 3.14E-38 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Gene3D G3DSA:1.10.275.40 229 366 1.0E-113 T 23-10-2018 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Pfam PF13307 Helicase C-terminal domain 444 616 7.3E-37 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 323 627 2.0E-78 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Gene3D G3DSA:3.40.50.300 19 398 1.0E-113 T 23-10-2018 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Pfam PF06733 DEAD_2 63 232 5.9E-32 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 SUPERFAMILY SSF52540 29 600 1.49E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Gene3D G3DSA:1.10.30.20 94 170 1.0E-113 T 23-10-2018 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 SMART SM00488 3 253 5.2E-69 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 SMART SM00487 7 276 1.3E-8 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 SUPERFAMILY SSF52540 6 232 5.41E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Pfam PF06777 Helical and beta-bridge domain 239 430 7.5E-64 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 SMART SM00491 461 603 4.0E-45 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TAM4_942 55dc4d4d080272c76aa05788f2aab6f8 640 Gene3D G3DSA:3.40.50.300 413 628 4.3E-43 T 23-10-2018 TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 Gene3D G3DSA:3.40.50.970 1 199 2.1E-84 T 23-10-2018 TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 Gene3D G3DSA:3.40.50.920 274 381 1.1E-24 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 SUPERFAMILY SSF52518 12 264 1.86E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 SUPERFAMILY SSF52922 275 378 2.36E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 3.2E-20 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TAM4_2160 45cebac9c45b9c90fc61ada865d26032 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 257 3.6E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 SUPERFAMILY SSF89124 126 366 2.62E-80 T 23-10-2018 IPR036070 Nop domain superfamily TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 Gene3D G3DSA:3.30.420.220 1 125 4.7E-45 T 23-10-2018 TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 Gene3D G3DSA:1.10.287.660 131 243 2.0E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 4.6E-72 T 23-10-2018 IPR002687 Nop domain TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 Gene3D G3DSA:1.10.246.90 244 368 7.6E-52 T 23-10-2018 TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 SMART SM00931 130 182 1.0E-27 T 23-10-2018 IPR012976 NOSIC TAM4_971 f642f1f9c57a64bcc44e46f9851c0302 422 Gene3D G3DSA:1.10.150.460 161 212 2.0E-39 T 23-10-2018 TAM4_103 57da6a6c8c99c8ab6e435906baccffc0 73 SUPERFAMILY SSF50182 8 73 6.87E-28 T 23-10-2018 IPR010920 LSM domain superfamily TAM4_103 57da6a6c8c99c8ab6e435906baccffc0 73 Gene3D G3DSA:2.30.30.100 4 73 3.1E-32 T 23-10-2018 TAM4_203 35558358d75050680a62fe1abb886210 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 6 292 1.9E-39 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TAM4_203 35558358d75050680a62fe1abb886210 300 SUPERFAMILY SSF55681 9 295 1.59E-51 T 23-10-2018 TAM4_203 35558358d75050680a62fe1abb886210 300 Gene3D G3DSA:3.30.930.10 1 299 1.3E-71 T 23-10-2018 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 SUPERFAMILY SSF55307 238 352 2.15E-33 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 PRINTS PR00423 Cell division protein FtsZ signature 122 142 6.0E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 PRINTS PR00423 Cell division protein FtsZ signature 220 242 6.0E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 PRINTS PR00423 Cell division protein FtsZ signature 243 264 6.0E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 PRINTS PR00423 Cell division protein FtsZ signature 158 179 6.0E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 SUPERFAMILY SSF52490 36 239 3.53E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 Gene3D G3DSA:3.40.50.1440 35 347 1.6E-98 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 402 33.353 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 SMART SM00864 37 236 3.7E-81 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 35 357 1.2E-109 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 SMART SM00865 238 355 2.6E-35 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 9.5E-42 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TAM4_370 b5693f1d1b861443c22d33f453314be4 417 Pfam PF12327 FtsZ family, C-terminal domain 253 347 3.2E-23 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 Gene3D G3DSA:1.10.10.10 2 82 1.5E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 1.0E-35 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 SUPERFAMILY SSF46785 3 78 6.23E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 PIRSF PIRSF019345 2 194 5.5E-46 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 Gene3D G3DSA:1.10.10.10 83 163 2.4E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 6.6E-32 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TAM4_1675 76a1702c124dc9aa64b82ebc7bd62cef 195 SUPERFAMILY SSF46785 85 152 2.79E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_304 41ef2965d1d3c878c9c12b050a5d7835 252 Gene3D G3DSA:3.60.21.10 2 252 9.1E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_304 41ef2965d1d3c878c9c12b050a5d7835 252 PIRSF PIRSF000883 1 252 3.6E-27 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 TAM4_304 41ef2965d1d3c878c9c12b050a5d7835 252 SUPERFAMILY SSF56300 3 251 1.27E-55 T 23-10-2018 TAM4_1939 5062f9b21e221f8d5119dba31302c73e 275 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 45 2.0E-15 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TAM4_1939 5062f9b21e221f8d5119dba31302c73e 275 Gene3D G3DSA:3.30.70.2660 3 238 4.2E-7 T 23-10-2018 TAM4_1939 5062f9b21e221f8d5119dba31302c73e 275 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 4 182 1.2E-30 T 23-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type TAM4_1939 5062f9b21e221f8d5119dba31302c73e 275 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 178 2.1E-20 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 Gene3D G3DSA:2.30.130.10 502 568 3.8E-24 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 Gene3D G3DSA:3.40.50.10630 252 423 1.5E-46 T 23-10-2018 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 SUPERFAMILY SSF52141 265 421 1.57E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 SMART SM00359 502 568 7.1E-8 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 SUPERFAMILY SSF88697 512 566 1.74E-12 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 Pfam PF01472 PUA domain 513 566 5.5E-10 T 23-10-2018 IPR002478 PUA domain GO:0003723 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 SUPERFAMILY SSF88802 247 500 9.81E-16 T 23-10-2018 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 SUPERFAMILY SSF51713 1 243 2.25E-20 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TAM4_168 f6c8de6fb5f1991268d0e29523e61d9d 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 6.1E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TAM4_2178 469ee9cf641fee2f0e1a8702e2c6e3df 306 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 187 199 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TAM4_2178 469ee9cf641fee2f0e1a8702e2c6e3df 306 SUPERFAMILY SSF48576 8 290 3.2E-68 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TAM4_2178 469ee9cf641fee2f0e1a8702e2c6e3df 306 Pfam PF00348 Polyprenyl synthetase 19 243 2.1E-51 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TAM4_2178 469ee9cf641fee2f0e1a8702e2c6e3df 306 Gene3D G3DSA:1.10.600.10 1 297 1.3E-72 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TAM4_631 bd0a2f8965af269f0ba9bdaafe6ec20a 166 Pfam PF01842 ACT domain 105 158 2.7E-7 T 23-10-2018 IPR002912 ACT domain TAM4_631 bd0a2f8965af269f0ba9bdaafe6ec20a 166 PIRSF PIRSF004897 1 166 7.2E-71 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TAM4_631 bd0a2f8965af269f0ba9bdaafe6ec20a 166 Gene3D G3DSA:3.30.70.260 104 165 4.1E-5 T 23-10-2018 TAM4_631 bd0a2f8965af269f0ba9bdaafe6ec20a 166 SUPERFAMILY SSF55021 105 164 8.02E-9 T 23-10-2018 TAM4_596 ef65343d8ac8a0f7b5d8971502407907 210 Gene3D G3DSA:3.90.320.10 3 203 3.5E-23 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TAM4_596 ef65343d8ac8a0f7b5d8971502407907 210 Pfam PF12705 PD-(D/E)XK nuclease superfamily 53 200 7.3E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TAM4_596 ef65343d8ac8a0f7b5d8971502407907 210 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 6 202 6.9E-30 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 TAM4_1066 d08b8d5f388007966d7571b210076270 161 Pfam PF01899 Na+/H+ ion antiporter subunit 9 159 1.1E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_1066 d08b8d5f388007966d7571b210076270 161 PIRSF PIRSF019239 1 161 1.9E-45 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_1893 aa075aa1e27ad3d17ac5ad1b852c4dfa 125 Gene3D G3DSA:1.20.120.330 2 124 2.2E-33 T 23-10-2018 TAM4_1893 aa075aa1e27ad3d17ac5ad1b852c4dfa 125 SUPERFAMILY SSF81593 8 123 4.32E-5 T 23-10-2018 TAM4_1893 aa075aa1e27ad3d17ac5ad1b852c4dfa 125 Pfam PF05168 HEPN domain 7 121 8.0E-27 T 23-10-2018 IPR007842 HEPN domain TAM4_663 39b5b61f24ea124a842026cd1aeffacc 660 SUPERFAMILY SSF52540 171 640 2.53E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_663 39b5b61f24ea124a842026cd1aeffacc 660 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 19 653 1.5E-250 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 TAM4_663 39b5b61f24ea124a842026cd1aeffacc 660 Pfam PF13087 AAA domain 429 630 8.2E-55 T 23-10-2018 TAM4_663 39b5b61f24ea124a842026cd1aeffacc 660 Pfam PF13086 AAA domain 175 424 1.1E-55 T 23-10-2018 TAM4_663 39b5b61f24ea124a842026cd1aeffacc 660 Gene3D G3DSA:3.40.50.300 452 656 1.5E-60 T 23-10-2018 TAM4_527 70d7c4ddf62dbc067dcf4007323d859e 398 Gene3D G3DSA:1.20.1250.20 2 192 5.1E-11 T 23-10-2018 TAM4_527 70d7c4ddf62dbc067dcf4007323d859e 398 Gene3D G3DSA:1.20.1250.20 193 391 2.0E-8 T 23-10-2018 TAM4_527 70d7c4ddf62dbc067dcf4007323d859e 398 SUPERFAMILY SSF103473 4 389 1.57E-31 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_527 70d7c4ddf62dbc067dcf4007323d859e 398 Pfam PF07690 Major Facilitator Superfamily 33 355 1.0E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Gene3D G3DSA:3.40.50.1980 213 339 4.0E-33 T 23-10-2018 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Pfam PF01497 Periplasmic binding protein 368 587 7.2E-39 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Pfam PF01497 Periplasmic binding protein 98 314 2.6E-33 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Gene3D G3DSA:3.40.50.1980 349 479 1.3E-35 T 23-10-2018 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Gene3D G3DSA:3.40.50.1980 80 209 5.3E-33 T 23-10-2018 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 Gene3D G3DSA:3.40.50.1980 486 613 3.4E-31 T 23-10-2018 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 SUPERFAMILY SSF53807 82 344 3.92E-67 T 23-10-2018 TAM4_686 cb71cbcf1599fd35c1910f6f2ae137d2 629 SUPERFAMILY SSF53807 352 616 2.84E-70 T 23-10-2018 TAM4_1870 638f552fd604de3992b6afc1ea91a147 140 Pfam PF01909 Nucleotidyltransferase domain 6 73 5.2E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1870 638f552fd604de3992b6afc1ea91a147 140 SUPERFAMILY SSF81301 5 105 5.54E-16 T 23-10-2018 TAM4_1870 638f552fd604de3992b6afc1ea91a147 140 Gene3D G3DSA:3.30.460.10 2 102 2.4E-16 T 23-10-2018 TAM4_1966 62ee22138d4f0e69e7522965283c79b8 61 Pfam PF04021 Class III signal peptide 3 26 1.8E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Gene3D G3DSA:2.60.40.1190 414 645 3.0E-62 T 23-10-2018 TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 SUPERFAMILY SSF49344 416 643 3.84E-67 T 23-10-2018 TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 416 641 1.1E-69 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 SUPERFAMILY SSF50998 67 343 4.71E-8 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Pfam PF08308 PEGA domain 861 928 9.3E-20 T 23-10-2018 IPR013229 PEGA TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Pfam PF08308 PEGA domain 653 717 3.9E-17 T 23-10-2018 IPR013229 PEGA TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Pfam PF08308 PEGA domain 721 788 2.6E-17 T 23-10-2018 IPR013229 PEGA TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Pfam PF08308 PEGA domain 791 858 1.6E-17 T 23-10-2018 IPR013229 PEGA TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 952 970 3.2E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_913 59f092a25e5f6bb79293e6d14f7a08c8 971 Gene3D G3DSA:2.80.10.50 81 200 5.1E-5 T 23-10-2018 TAM4_668 ca62f3188e432b1330e4bf6820d51029 193 SUPERFAMILY SSF53335 3 180 4.48E-42 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_668 ca62f3188e432b1330e4bf6820d51029 193 Gene3D G3DSA:3.40.50.150 13 193 2.3E-44 T 23-10-2018 TAM4_668 ca62f3188e432b1330e4bf6820d51029 193 Pfam PF05175 Methyltransferase small domain 22 163 2.0E-18 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TAM4_668 ca62f3188e432b1330e4bf6820d51029 193 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 188 2.0E-55 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 TAM4_998 711a5eaa5025b05b0ad55941f3c6eff5 217 SUPERFAMILY SSF56300 21 165 1.2E-17 T 23-10-2018 TAM4_998 711a5eaa5025b05b0ad55941f3c6eff5 217 Pfam PF00149 Calcineurin-like phosphoesterase 21 109 4.4E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_998 711a5eaa5025b05b0ad55941f3c6eff5 217 PIRSF PIRSF000887 7 215 6.8E-36 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TAM4_998 711a5eaa5025b05b0ad55941f3c6eff5 217 Gene3D G3DSA:3.60.21.10 21 126 1.5E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_1844 2b7e222f20162059d8a839903819bf3a 223 Gene3D G3DSA:3.60.110.10 1 221 1.7E-31 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TAM4_1844 2b7e222f20162059d8a839903819bf3a 223 Pfam PF00795 Carbon-nitrogen hydrolase 2 167 7.2E-16 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TAM4_1844 2b7e222f20162059d8a839903819bf3a 223 SUPERFAMILY SSF56317 1 191 4.71E-35 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TAM4_318 4664618ac12dbfb3f78e93f7839f9253 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TAM4_318 4664618ac12dbfb3f78e93f7839f9253 343 Gene3D G3DSA:1.10.600.10 1 343 7.3E-136 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TAM4_318 4664618ac12dbfb3f78e93f7839f9253 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TAM4_318 4664618ac12dbfb3f78e93f7839f9253 343 SUPERFAMILY SSF48576 3 342 2.59E-98 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TAM4_318 4664618ac12dbfb3f78e93f7839f9253 343 Pfam PF00348 Polyprenyl synthetase 32 270 6.0E-72 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TAM4_96 e162992c1a4ded1334f3f427d17a6aee 343 Pfam PF05763 Protein of unknown function (DUF835) 213 336 3.0E-27 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 Pfam PF00571 CBS domain 122 176 5.5E-13 T 23-10-2018 IPR000644 CBS domain TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 Pfam PF00571 CBS domain 47 97 2.0E-11 T 23-10-2018 IPR000644 CBS domain TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 SMART SM00116 129 177 3.4E-9 T 23-10-2018 IPR000644 CBS domain TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 SMART SM00116 51 98 2.0E-5 T 23-10-2018 IPR000644 CBS domain TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 SUPERFAMILY SSF54631 32 176 9.27E-30 T 23-10-2018 TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 Gene3D G3DSA:3.10.580.10 8 98 2.8E-12 T 23-10-2018 TAM4_1382 0ccf17aa2dcb20a0f11a7cb820782bf8 181 Gene3D G3DSA:3.10.580.10 101 178 2.8E-16 T 23-10-2018 TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 Gene3D G3DSA:3.90.550.10 1 220 3.5E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 317 4.4E-10 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 Pfam PF12804 MobA-like NTP transferase domain 6 113 3.0E-17 T 23-10-2018 IPR025877 MobA-like NTP transferase TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 SUPERFAMILY SSF53448 2 221 3.83E-34 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_5 2b9ea5e7172e8c2900cb82b5f9db4c75 432 Gene3D G3DSA:1.20.120.1760 230 424 7.1E-56 T 23-10-2018 TAM4_1636 fc437bcabdd4e18dc067b928c9026b78 232 SUPERFAMILY SSF52540 3 221 2.13E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1636 fc437bcabdd4e18dc067b928c9026b78 232 Pfam PF06745 KaiC 15 220 7.6E-20 T 23-10-2018 IPR014774 KaiC-like domain TAM4_1636 fc437bcabdd4e18dc067b928c9026b78 232 Gene3D G3DSA:3.40.50.300 2 232 6.2E-45 T 23-10-2018 TAM4_2015 526ffd06f91feaa5a96618a327624a6c 261 Gene3D G3DSA:3.40.50.720 1 248 1.1E-30 T 23-10-2018 TAM4_2015 526ffd06f91feaa5a96618a327624a6c 261 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 160 4.8E-9 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TAM4_2015 526ffd06f91feaa5a96618a327624a6c 261 SUPERFAMILY SSF51735 2 244 6.13E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_671 78a719d64eba2dd7012fb77332b34c04 148 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 1.9E-24 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 TAM4_1653 97345d6580ed6627f1f0f728b7d395ea 221 Pfam PF01980 Uncharacterised protein family UPF0066 16 125 2.4E-31 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TAM4_1653 97345d6580ed6627f1f0f728b7d395ea 221 SUPERFAMILY SSF118196 4 134 8.11E-40 T 23-10-2018 IPR036413 YaeB-like superfamily TAM4_1653 97345d6580ed6627f1f0f728b7d395ea 221 ProSitePatterns PS01318 TsaA-like domain signature. 73 84 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TAM4_1653 97345d6580ed6627f1f0f728b7d395ea 221 Gene3D G3DSA:2.40.30.70 3 143 8.5E-34 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily TAM4_1653 97345d6580ed6627f1f0f728b7d395ea 221 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 16 129 4.8E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TAM4_534 fbf3d10daff4ae8864ff0b2c35af469c 179 SUPERFAMILY SSF53448 2 174 1.51E-20 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_534 fbf3d10daff4ae8864ff0b2c35af469c 179 Pfam PF12804 MobA-like NTP transferase domain 3 112 3.1E-18 T 23-10-2018 IPR025877 MobA-like NTP transferase TAM4_534 fbf3d10daff4ae8864ff0b2c35af469c 179 Gene3D G3DSA:3.90.550.10 2 175 6.9E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1058 2f323dbd10377e85e8be141b50c2ae64 123 SUPERFAMILY SSF53146 1 109 6.41E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_1058 2f323dbd10377e85e8be141b50c2ae64 123 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 2.8E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TAM4_1058 2f323dbd10377e85e8be141b50c2ae64 123 Gene3D G3DSA:3.30.420.130 1 104 1.7E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_1669 d3ed5b89a01432ba9045ad653f815691 185 SUPERFAMILY SSF52540 2 183 2.71E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1669 d3ed5b89a01432ba9045ad653f815691 185 SMART SM00382 1 183 5.6E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_1669 d3ed5b89a01432ba9045ad653f815691 185 Gene3D G3DSA:3.40.50.300 1 185 4.0E-52 T 23-10-2018 TAM4_1669 d3ed5b89a01432ba9045ad653f815691 185 Pfam PF00005 ABC transporter 2 134 4.2E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_1669 d3ed5b89a01432ba9045ad653f815691 185 ProSitePatterns PS00211 ABC transporters family signature. 106 120 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_1387 7d50f6f44d45d56479d6c9fb371611ae 617 SUPERFAMILY SSF161098 406 598 1.02E-21 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1387 7d50f6f44d45d56479d6c9fb371611ae 617 Gene3D G3DSA:1.10.3720.10 400 616 9.5E-21 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1387 7d50f6f44d45d56479d6c9fb371611ae 617 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 53 1.2E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TAM4_1387 7d50f6f44d45d56479d6c9fb371611ae 617 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 429 616 1.5E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1878 c6f92e5796465af9a20fce102db500d2 472 Gene3D G3DSA:3.30.2290.10 1 194 6.9E-25 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_1878 c6f92e5796465af9a20fce102db500d2 472 SUPERFAMILY SSF111283 2 467 3.92E-103 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_1878 c6f92e5796465af9a20fce102db500d2 472 PIRSF PIRSF004919 1 471 1.1E-152 T 23-10-2018 IPR025502 TldD TAM4_1878 c6f92e5796465af9a20fce102db500d2 472 Pfam PF01523 Putative modulator of DNA gyrase 18 324 1.7E-57 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_2055 67ba0b8c9b195881801fa25cdc5e4ee9 131 SUPERFAMILY SSF54637 13 119 7.21E-25 T 23-10-2018 IPR029069 HotDog domain superfamily TAM4_2055 67ba0b8c9b195881801fa25cdc5e4ee9 131 Pfam PF03061 Thioesterase superfamily 40 108 5.0E-7 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TAM4_2055 67ba0b8c9b195881801fa25cdc5e4ee9 131 Gene3D G3DSA:3.10.129.10 1 129 2.5E-39 T 23-10-2018 TAM4_2055 67ba0b8c9b195881801fa25cdc5e4ee9 131 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 119 3.2E-10 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TAM4_492 3392fadc3e7331d16060130a0e97010c 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 1.4E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_492 3392fadc3e7331d16060130a0e97010c 271 SUPERFAMILY SSF56281 3 252 2.44E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_492 3392fadc3e7331d16060130a0e97010c 271 Gene3D G3DSA:3.60.15.10 1 253 6.7E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1839 875fc4d5deaf8df8b52216015a571220 153 Gene3D G3DSA:1.25.40.10 49 153 3.4E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1839 875fc4d5deaf8df8b52216015a571220 153 SUPERFAMILY SSF48452 21 144 4.14E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_17 0cbf12886ac76f296981e791cecda802 638 SUPERFAMILY SSF54211 47 233 2.12E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_17 0cbf12886ac76f296981e791cecda802 638 Gene3D G3DSA:3.30.230.10 33 225 1.9E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_17 0cbf12886ac76f296981e791cecda802 638 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 619 638 1.6E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_17 0cbf12886ac76f296981e791cecda802 638 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 110 129 3.3E-8 T 23-10-2018 TAM4_17 0cbf12886ac76f296981e791cecda802 638 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 140 159 3.3E-8 T 23-10-2018 TAM4_17 0cbf12886ac76f296981e791cecda802 638 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 163 181 3.3E-8 T 23-10-2018 TAM4_17 0cbf12886ac76f296981e791cecda802 638 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 94 181 3.8E-14 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TAM4_1121 7b69a67b6364c0ba03c6b09ffce136cd 233 SUPERFAMILY SSF75217 3 175 1.57E-32 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_1121 7b69a67b6364c0ba03c6b09ffce136cd 233 PIRSF PIRSF004808 1 233 7.5E-73 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TAM4_1121 7b69a67b6364c0ba03c6b09ffce136cd 233 Gene3D G3DSA:3.40.1280.10 1 157 3.5E-51 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TAM4_1121 7b69a67b6364c0ba03c6b09ffce136cd 233 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 229 3.2E-62 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TAM4_1121 7b69a67b6364c0ba03c6b09ffce136cd 233 Pfam PF00588 SpoU rRNA Methylase family 2 150 2.8E-33 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TAM4_494 e33d32ff38af134f63e65e9bb53ac4bc 436 Pfam PF08494 DEAD/H associated 205 392 1.3E-55 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TAM4_455 41fc673e8aa7975afa8223303c0b17fa 67 SUPERFAMILY SSF47113 3 66 3.18E-19 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_455 41fc673e8aa7975afa8223303c0b17fa 67 SMART SM00803 12 66 0.0046 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 TAM4_455 41fc673e8aa7975afa8223303c0b17fa 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 9.3E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TAM4_455 41fc673e8aa7975afa8223303c0b17fa 67 Gene3D G3DSA:1.10.20.10 1 67 3.1E-22 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TAM4_2174 e036065a8373bf1b9f0dc5756c8f151f 174 Gene3D G3DSA:1.20.1260.10 12 161 3.5E-49 T 23-10-2018 IPR012347 Ferritin-like TAM4_2174 e036065a8373bf1b9f0dc5756c8f151f 174 Pfam PF02915 Rubrerythrin 22 157 1.1E-30 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_2174 e036065a8373bf1b9f0dc5756c8f151f 174 SUPERFAMILY SSF47240 14 163 1.04E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_2346 c4e244ab7fde0ebe5789dec9f6414bf4 177 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TAM4_2346 c4e244ab7fde0ebe5789dec9f6414bf4 177 SUPERFAMILY SSF53927 22 147 3.9E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TAM4_2346 c4e244ab7fde0ebe5789dec9f6414bf4 177 Gene3D G3DSA:3.40.140.10 18 165 1.8E-48 T 23-10-2018 TAM4_2346 c4e244ab7fde0ebe5789dec9f6414bf4 177 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 2.9E-29 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TAM4_2346 c4e244ab7fde0ebe5789dec9f6414bf4 177 PIRSF PIRSF006019 12 168 2.4E-57 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TAM4_626 03fb2f0d0f7542a0d70c22d897521952 419 SUPERFAMILY SSF53383 15 411 1.5E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_626 03fb2f0d0f7542a0d70c22d897521952 419 Gene3D G3DSA:3.90.1150.10 34 409 2.0E-164 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_626 03fb2f0d0f7542a0d70c22d897521952 419 Pfam PF00155 Aminotransferase class I and II 45 405 2.5E-42 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TAM4_626 03fb2f0d0f7542a0d70c22d897521952 419 Gene3D G3DSA:3.40.640.10 79 304 2.0E-164 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_2080 d6819d18d5194dbdc8231ac3e0d3a842 169 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 166 3.9E-65 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TAM4_2080 d6819d18d5194dbdc8231ac3e0d3a842 169 Pfam PF01936 NYN domain 31 162 1.7E-17 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TAM4_2080 d6819d18d5194dbdc8231ac3e0d3a842 169 Gene3D G3DSA:3.40.50.1010 23 164 2.6E-8 T 23-10-2018 TAM4_2080 d6819d18d5194dbdc8231ac3e0d3a842 169 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 32 104 1.0E-31 T 23-10-2018 TAM4_1628 2679dfd51a200bcf7bbc3556a1a0251d 614 SUPERFAMILY SSF52540 20 328 1.78E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1628 2679dfd51a200bcf7bbc3556a1a0251d 614 Pfam PF07693 KAP family P-loop domain 20 331 1.8E-41 T 23-10-2018 IPR011646 KAP family P-loop domain TAM4_1398 3393b5e410c50fd29883c41012a6a22e 311 SUPERFAMILY SSF52518 16 309 2.42E-73 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_1398 3393b5e410c50fd29883c41012a6a22e 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 1.8E-20 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_1398 3393b5e410c50fd29883c41012a6a22e 311 Gene3D G3DSA:3.40.50.970 11 101 1.3E-5 T 23-10-2018 TAM4_1398 3393b5e410c50fd29883c41012a6a22e 311 Gene3D G3DSA:3.40.50.970 102 310 1.6E-68 T 23-10-2018 TAM4_2372 ed93a83b5689f66d06bce9029230634a 65 Pfam PF05168 HEPN domain 2 63 1.0E-7 T 23-10-2018 IPR007842 HEPN domain TAM4_2372 ed93a83b5689f66d06bce9029230634a 65 Gene3D G3DSA:1.20.120.330 1 64 2.7E-13 T 23-10-2018 TAM4_885 245f1adc09c3bf066b75eac1eebd82f3 489 Pfam PF02386 Cation transport protein 58 480 1.1E-66 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TAM4_885 245f1adc09c3bf066b75eac1eebd82f3 489 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 1.5E-113 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TAM4_2000 14e5320832d87fe8a6d378ea46649875 507 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 485 1.2E-147 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TAM4_2000 14e5320832d87fe8a6d378ea46649875 507 PIRSF PIRSF006446 1 503 8.0E-132 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TAM4_524 1bd132e316cb5a11f0b166e81076e3c3 304 Gene3D G3DSA:1.20.58.220 134 232 1.1E-9 T 23-10-2018 IPR038078 PhoU-like domain superfamily TAM4_524 1bd132e316cb5a11f0b166e81076e3c3 304 SMART SM00966 8 54 6.7E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_524 1bd132e316cb5a11f0b166e81076e3c3 304 SUPERFAMILY SSF109755 125 301 8.5E-16 T 23-10-2018 TAM4_524 1bd132e316cb5a11f0b166e81076e3c3 304 Pfam PF01895 PhoU domain 139 230 1.1E-11 T 23-10-2018 IPR026022 PhoU domain TAM4_524 1bd132e316cb5a11f0b166e81076e3c3 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 1.2E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 PIRSF PIRSF005590 1 180 2.6E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 Gene3D G3DSA:3.90.1170.10 1 180 2.5E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 SUPERFAMILY SSF54686 4 166 1.19E-55 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 1.1E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TAM4_239 19d7d2a96805ed56762eef22a3ad3f21 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.785 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea TAM4_1997 9860b72adb173d0c7487288ecd6f2862 386 Gene3D G3DSA:1.10.10.10 255 323 4.3E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1997 9860b72adb173d0c7487288ecd6f2862 386 SUPERFAMILY SSF46785 258 320 4.17E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1997 9860b72adb173d0c7487288ecd6f2862 386 SUPERFAMILY SSF46785 333 382 1.09E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1997 9860b72adb173d0c7487288ecd6f2862 386 Gene3D G3DSA:1.10.10.10 324 386 4.1E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1997 9860b72adb173d0c7487288ecd6f2862 386 Pfam PF13936 Helix-turn-helix domain 339 368 7.2E-9 T 23-10-2018 IPR025246 Transposase IS30-like HTH domain TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 Pfam PF01861 Protein of unknown function DUF43 106 350 1.2E-120 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.436 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 Gene3D G3DSA:3.40.50.150 101 326 1.1E-84 T 23-10-2018 TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 Gene3D G3DSA:1.10.10.10 1 83 1.0E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 PIRSF PIRSF005895 1 351 1.2E-156 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TAM4_1077 2b22e3f89a0bba6754f80ea6741bd518 351 SUPERFAMILY SSF53335 166 285 3.21E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_822 996ddd0722dda9f15ceca226df58a3ad 66 Gene3D G3DSA:4.10.1150.10 1 63 1.1E-10 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_822 996ddd0722dda9f15ceca226df58a3ad 66 SUPERFAMILY SSF141694 1 41 1.88E-11 T 23-10-2018 TAM4_822 996ddd0722dda9f15ceca226df58a3ad 66 Pfam PF01954 Protein of unknown function DUF104 1 49 2.1E-12 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_64 de005bed52604f8b369605e33160ffc0 170 SUPERFAMILY SSF54814 39 96 8.5E-9 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TAM4_64 de005bed52604f8b369605e33160ffc0 170 Pfam PF13184 NusA-like KH domain 57 124 5.7E-11 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TAM4_64 de005bed52604f8b369605e33160ffc0 170 SMART SM00322 57 158 3.7E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TAM4_64 de005bed52604f8b369605e33160ffc0 170 Gene3D G3DSA:3.30.300.20 47 97 4.2E-8 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_1598 2c9d3a15b55cdd438066be7d3ff98883 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 135 1.7E-8 T 23-10-2018 TAM4_1598 2c9d3a15b55cdd438066be7d3ff98883 226 Gene3D G3DSA:1.10.150.240 14 83 1.4E-10 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TAM4_1598 2c9d3a15b55cdd438066be7d3ff98883 226 SUPERFAMILY SSF56784 1 185 2.0E-18 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_1598 2c9d3a15b55cdd438066be7d3ff98883 226 Gene3D G3DSA:3.40.50.1000 3 136 1.4E-10 T 23-10-2018 IPR023214 HAD superfamily TAM4_368 842e631cab05d9fcd17deb83d06846a7 83 Gene3D G3DSA:3.10.20.30 1 83 1.6E-24 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TAM4_368 842e631cab05d9fcd17deb83d06846a7 83 Pfam PF02597 ThiS family 4 83 1.1E-19 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TAM4_368 842e631cab05d9fcd17deb83d06846a7 83 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 83 1.9E-24 T 23-10-2018 IPR010038 MoaD, archaeal-type TAM4_368 842e631cab05d9fcd17deb83d06846a7 83 SUPERFAMILY SSF54285 2 83 1.74E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TAM4_1362 19f56d500234013762a8944a33082f67 295 SUPERFAMILY SSF53613 1 272 1.45E-63 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1362 19f56d500234013762a8944a33082f67 295 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 226 239 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TAM4_1362 19f56d500234013762a8944a33082f67 295 PRINTS PR00990 Ribokinase signature 196 207 7.3E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TAM4_1362 19f56d500234013762a8944a33082f67 295 PRINTS PR00990 Ribokinase signature 103 116 7.3E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TAM4_1362 19f56d500234013762a8944a33082f67 295 PRINTS PR00990 Ribokinase signature 6 27 7.3E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TAM4_1362 19f56d500234013762a8944a33082f67 295 PRINTS PR00990 Ribokinase signature 164 179 7.3E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TAM4_1362 19f56d500234013762a8944a33082f67 295 PRINTS PR00990 Ribokinase signature 33 52 7.3E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TAM4_1362 19f56d500234013762a8944a33082f67 295 Pfam PF00294 pfkB family carbohydrate kinase 3 271 7.6E-43 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TAM4_1362 19f56d500234013762a8944a33082f67 295 Gene3D G3DSA:3.40.1190.20 1 281 7.6E-63 T 23-10-2018 IPR029056 Ribokinase-like TAM4_1265 d42a9a5bcc49d09c2e1ac826f8864418 335 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 321 3.5E-63 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_1265 d42a9a5bcc49d09c2e1ac826f8864418 335 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 10 330 6.3E-69 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_883 dadb40c6acad6d89a2391edcfe3bb5be 406 Gene3D G3DSA:1.20.120.1220 56 183 1.8E-14 T 23-10-2018 TAM4_883 dadb40c6acad6d89a2391edcfe3bb5be 406 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 261 370 3.0E-30 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea TAM4_1816 e7713be4b8bd09a3414c1760b247d571 97 Gene3D G3DSA:3.30.70.930 1 94 6.2E-35 T 23-10-2018 IPR029756 MTH1187/YkoF-like TAM4_1816 e7713be4b8bd09a3414c1760b247d571 97 Pfam PF01910 Thiamine-binding protein 1 90 1.3E-32 T 23-10-2018 IPR002767 Thiamine-binding protein TAM4_1816 e7713be4b8bd09a3414c1760b247d571 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 93 2.2E-27 T 23-10-2018 IPR002767 Thiamine-binding protein TAM4_1816 e7713be4b8bd09a3414c1760b247d571 97 SUPERFAMILY SSF89957 1 92 3.92E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like TAM4_984 68bf105888be0608308573fbffc75e2d 441 Gene3D G3DSA:3.50.50.60 43 241 4.9E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_984 68bf105888be0608308573fbffc75e2d 441 Gene3D G3DSA:3.50.50.60 320 441 1.4E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 5.3E-22 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 5.3E-22 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 5.3E-22 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 5.3E-22 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 5.3E-22 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 303 2.6E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_984 68bf105888be0608308573fbffc75e2d 441 SUPERFAMILY SSF51905 4 344 1.4E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_984 68bf105888be0608308573fbffc75e2d 441 Gene3D G3DSA:3.50.50.60 4 314 4.9E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_984 68bf105888be0608308573fbffc75e2d 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 427 9.6E-19 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TAM4_984 68bf105888be0608308573fbffc75e2d 441 SUPERFAMILY SSF55424 320 438 6.53E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.3E-28 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.3E-28 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.3E-28 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.3E-28 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.3E-28 T 23-10-2018 TAM4_984 68bf105888be0608308573fbffc75e2d 441 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 4 436 7.3E-181 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 TAM4_1421 56c709b8d67a4ee313345f2fdba1839a 177 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 20 171 5.3E-13 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 34.034 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 PIRSF PIRSF018644 5 471 1.7E-189 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 SUPERFAMILY SSF159234 319 471 2.09E-29 T 23-10-2018 IPR035930 FomD-like superfamily TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 Gene3D G3DSA:2.40.380.10 374 471 1.2E-9 T 23-10-2018 IPR035930 FomD-like superfamily TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 Pfam PF10150 Ribonuclease E/G family 152 262 1.5E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TAM4_49 68bcabcb0b742288ed01a304ac1044fe 471 Pfam PF04167 Protein of unknown function (DUF402) 377 443 9.6E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TAM4_11 71ded419ed79afac59fd4258787b3d3f 127 Pfam PF01850 PIN domain 4 121 3.2E-19 T 23-10-2018 IPR002716 PIN domain TAM4_11 71ded419ed79afac59fd4258787b3d3f 127 Gene3D G3DSA:3.40.50.1010 1 125 5.0E-14 T 23-10-2018 TAM4_11 71ded419ed79afac59fd4258787b3d3f 127 SUPERFAMILY SSF88723 4 124 8.69E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 Gene3D G3DSA:3.40.190.10 208 444 2.7E-128 T 23-10-2018 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 203 220 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 PRINTS PR00181 Maltose binding protein signature 429 448 4.9E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 PRINTS PR00181 Maltose binding protein signature 138 156 4.9E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 PRINTS PR00181 Maltose binding protein signature 200 219 4.9E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 PRINTS PR00181 Maltose binding protein signature 298 317 4.9E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 Gene3D G3DSA:3.40.190.10 101 429 2.7E-128 T 23-10-2018 TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 Pfam PF13416 Bacterial extracellular solute-binding protein 116 413 8.7E-55 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TAM4_967 b1c46207b31c5325dd9d2c10081a40a4 472 SUPERFAMILY SSF53850 95 467 1.09E-93 T 23-10-2018 TAM4_449 c24ff0a3f9938c5a4f63a503842ec12e 190 Gene3D G3DSA:3.40.50.300 2 183 1.9E-44 T 23-10-2018 TAM4_449 c24ff0a3f9938c5a4f63a503842ec12e 190 Pfam PF13207 AAA domain 6 137 6.4E-19 T 23-10-2018 TAM4_449 c24ff0a3f9938c5a4f63a503842ec12e 190 Hamap MF_01111 UPF0200 protein . 2 182 31.489 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related TAM4_449 c24ff0a3f9938c5a4f63a503842ec12e 190 SUPERFAMILY SSF52540 1 178 1.21E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1604 3e7662cfeed97fe7bb1e11694c22564f 168 Pfam PF04434 SWIM zinc finger 35 61 8.1E-6 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 SUPERFAMILY SSF54631 8 153 1.94E-21 T 23-10-2018 TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 SMART SM00116 106 153 0.0011 T 23-10-2018 IPR000644 CBS domain TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 SMART SM00116 25 73 15.0 T 23-10-2018 IPR000644 CBS domain TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 Pfam PF00571 CBS domain 26 72 8.4E-5 T 23-10-2018 IPR000644 CBS domain TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 Pfam PF00571 CBS domain 99 150 1.4E-7 T 23-10-2018 IPR000644 CBS domain TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 Gene3D G3DSA:3.10.580.10 78 157 2.7E-10 T 23-10-2018 TAM4_1597 848b8020c755c2f6b70a3cdba03e5677 175 Gene3D G3DSA:3.10.580.10 1 76 6.0E-6 T 23-10-2018 TAM4_1992 492e672567827cf5c85fc5d02fa36064 352 Gene3D G3DSA:3.40.50.1980 24 352 4.2E-55 T 23-10-2018 TAM4_1992 492e672567827cf5c85fc5d02fa36064 352 Pfam PF01497 Periplasmic binding protein 57 304 7.1E-25 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TAM4_1992 492e672567827cf5c85fc5d02fa36064 352 SUPERFAMILY SSF53807 37 334 8.24E-45 T 23-10-2018 TAM4_317 d52b94957c2c7943812a778c8fded415 76 SMART SM00966 3 44 2.1E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_317 d52b94957c2c7943812a778c8fded415 76 SUPERFAMILY SSF89447 2 56 5.62E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_317 d52b94957c2c7943812a778c8fded415 76 Gene3D G3DSA:2.40.330.20 1 75 5.8E-6 T 23-10-2018 IPR038619 MraZ superfamily TAM4_2355 e41b17b26162f698ffe232dbacb79067 183 Pfam PF00857 Isochorismatase family 5 178 1.1E-45 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 TAM4_2355 e41b17b26162f698ffe232dbacb79067 183 SUPERFAMILY SSF52499 4 180 4.06E-56 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TAM4_2355 e41b17b26162f698ffe232dbacb79067 183 Gene3D G3DSA:3.40.50.850 1 180 5.8E-74 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TAM4_2016 99bf64bd2aab3ef5f44ed58d2a1837ca 97 Gene3D G3DSA:1.10.287.1080 1 79 2.2E-29 T 23-10-2018 TAM4_2016 99bf64bd2aab3ef5f44ed58d2a1837ca 97 SUPERFAMILY SSF101386 1 79 5.56E-22 T 23-10-2018 TAM4_2016 99bf64bd2aab3ef5f44ed58d2a1837ca 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 82 1.4E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 SUPERFAMILY SSF55920 123 347 3.53E-84 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 Gene3D G3DSA:3.40.350.10 1 122 5.3E-30 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 7.3E-25 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 SUPERFAMILY SSF53092 6 124 9.42E-26 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 Pfam PF00557 Metallopeptidase family M24 133 334 5.2E-70 T 23-10-2018 IPR000994 Peptidase M24 TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 Gene3D G3DSA:3.90.230.10 123 348 5.3E-89 T 23-10-2018 TAM4_2152 f14ee48686cd57223d70eeddd1181491 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TAM4_141 895f374ff49bc9e862862933b151d4dd 282 PIRSF PIRSF006593 1 282 1.3E-100 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 TAM4_141 895f374ff49bc9e862862933b151d4dd 282 Gene3D G3DSA:1.10.8.380 1 67 5.1E-24 T 23-10-2018 TAM4_141 895f374ff49bc9e862862933b151d4dd 282 Gene3D G3DSA:1.10.285.20 68 131 1.3E-20 T 23-10-2018 TAM4_141 895f374ff49bc9e862862933b151d4dd 282 Pfam PF01937 Protein of unknown function DUF89 4 276 3.1E-55 T 23-10-2018 IPR002791 Domain of unknown function DUF89 TAM4_141 895f374ff49bc9e862862933b151d4dd 282 SUPERFAMILY SSF111321 1 281 5.89E-82 T 23-10-2018 IPR036075 AF1104-like superfamily TAM4_141 895f374ff49bc9e862862933b151d4dd 282 Gene3D G3DSA:3.40.50.10880 132 282 1.9E-59 T 23-10-2018 TAM4_2188 579f1fe6bec691531ee1c7750f116de8 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 1.9E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TAM4_2188 579f1fe6bec691531ee1c7750f116de8 281 SUPERFAMILY SSF52518 19 273 8.94E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TAM4_2188 579f1fe6bec691531ee1c7750f116de8 281 Gene3D G3DSA:3.40.50.970 86 277 3.8E-28 T 23-10-2018 TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 SUPERFAMILY SSF53448 1 379 2.94E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 Pfam PF00483 Nucleotidyl transferase 4 253 7.2E-40 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 Gene3D G3DSA:3.90.550.10 1 263 7.7E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 Gene3D G3DSA:2.160.10.10 264 411 7.2E-17 T 23-10-2018 TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 342 369 3.4E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_860 8c4931ddd53f1ceb90afe835a72ed5fb 413 SUPERFAMILY SSF51161 297 391 4.1E-16 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TAM4_1341 79a3a0e7037ef7bed295d4e395acccc6 209 SUPERFAMILY SSF111278 2 183 2.09E-48 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_1341 79a3a0e7037ef7bed295d4e395acccc6 209 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 26.48 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TAM4_1341 79a3a0e7037ef7bed295d4e395acccc6 209 Gene3D G3DSA:3.30.1960.10 1 188 3.2E-47 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_1341 79a3a0e7037ef7bed295d4e395acccc6 209 Pfam PF02676 Methyltransferase TYW3 4 184 4.8E-37 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TAM4_1471 b593d795466c624da3b7935109e46423 220 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 5.2E-48 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TAM4_1471 b593d795466c624da3b7935109e46423 220 Gene3D G3DSA:3.40.1280.10 1 219 1.1E-74 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TAM4_1471 b593d795466c624da3b7935109e46423 220 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.702 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 TAM4_1471 b593d795466c624da3b7935109e46423 220 SUPERFAMILY SSF75217 1 215 4.84E-61 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TAM4_1306 8f5eca43e9dd3db98dbbce4c3007a962 358 SUPERFAMILY SSF52540 3 283 1.33E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1306 8f5eca43e9dd3db98dbbce4c3007a962 358 Gene3D G3DSA:1.10.8.60 210 287 1.9E-15 T 23-10-2018 TAM4_1306 8f5eca43e9dd3db98dbbce4c3007a962 358 Gene3D G3DSA:3.40.50.300 3 209 4.0E-23 T 23-10-2018 TAM4_1198 531d74b07f07cd43864bbaa6aca6e61a 368 SUPERFAMILY SSF52540 15 194 1.45E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1198 531d74b07f07cd43864bbaa6aca6e61a 368 Pfam PF13173 AAA domain 27 159 1.1E-20 T 23-10-2018 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 47.323 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 PIRSF PIRSF006815 3 448 2.4E-156 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 Pfam PF02347 Glycine cleavage system P-protein 7 444 8.9E-123 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 Gene3D G3DSA:3.40.640.10 81 351 5.4E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 Gene3D G3DSA:3.90.1150.10 70 444 5.4E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_1744 e231371a26298f2ccd82189cc2b7a2d7 450 SUPERFAMILY SSF53383 3 447 3.27E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_508 084cb1b0594e50de87eca158a0736635 97 Gene3D G3DSA:1.10.10.10 5 94 8.8E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_508 084cb1b0594e50de87eca158a0736635 97 Pfam PF12840 Helix-turn-helix domain 10 64 1.4E-14 T 23-10-2018 TAM4_508 084cb1b0594e50de87eca158a0736635 97 SUPERFAMILY SSF46785 5 86 4.12E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_508 084cb1b0594e50de87eca158a0736635 97 SMART SM00418 10 91 2.0E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_718 9bd3c544b1f5c776d95c4090b07ff713 752 SUPERFAMILY SSF63825 6 107 5.23E-7 T 23-10-2018 TAM4_938 10596230b140e9675ea6d420fb20842d 317 Pfam PF04055 Radical SAM superfamily 25 192 1.4E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_938 10596230b140e9675ea6d420fb20842d 317 SMART SM00729 15 228 0.003 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TAM4_938 10596230b140e9675ea6d420fb20842d 317 SUPERFAMILY SSF102114 25 227 1.57E-20 T 23-10-2018 TAM4_938 10596230b140e9675ea6d420fb20842d 317 Gene3D G3DSA:3.20.20.70 19 242 2.3E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 TIGRFAM TIGR00746 arcC: carbamate kinase 2 312 2.2E-147 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 183 201 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 76 94 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 268 283 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 160 179 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 111 130 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PRINTS PR01469 Bacterial carbamate kinase signature 213 228 5.1E-69 T 23-10-2018 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 Gene3D G3DSA:3.40.1160.10 1 312 1.1E-137 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 SUPERFAMILY SSF53633 1 312 9.82E-91 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 Pfam PF00696 Amino acid kinase family 2 294 4.2E-31 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TAM4_1238 6791fde09f370d634ecfe4615b275d86 313 PIRSF PIRSF000723 1 313 1.9E-143 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TAM4_214 c50cd7a35350e6e3de3816498ebb4b1c 379 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 373 4.3E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TAM4_214 c50cd7a35350e6e3de3816498ebb4b1c 379 PIRSF PIRSF015658 1 379 2.7E-167 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TAM4_214 c50cd7a35350e6e3de3816498ebb4b1c 379 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 377 5.7E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TAM4_1934 87f4693ae3c70b7c1d5a722b33460cdc 263 PIRSF PIRSF036670 3 263 1.1E-121 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related TAM4_1934 87f4693ae3c70b7c1d5a722b33460cdc 263 Gene3D G3DSA:3.40.50.620 21 215 1.1E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_1934 87f4693ae3c70b7c1d5a722b33460cdc 263 SUPERFAMILY SSF52402 22 206 1.15E-32 T 23-10-2018 TAM4_1934 87f4693ae3c70b7c1d5a722b33460cdc 263 Pfam PF06508 Queuosine biosynthesis protein QueC 24 84 1.5E-7 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TAM4_454 deed81795518aad66a9503950d59069b 165 Gene3D G3DSA:3.40.630.30 2 158 1.1E-51 T 23-10-2018 TAM4_454 deed81795518aad66a9503950d59069b 165 Pfam PF00583 Acetyltransferase (GNAT) family 40 140 2.2E-22 T 23-10-2018 IPR000182 GNAT domain TAM4_454 deed81795518aad66a9503950d59069b 165 SUPERFAMILY SSF55729 2 153 3.16E-31 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1586 a1541a7088aaf6329ea54af4771e3820 235 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 68 6.8E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_1586 a1541a7088aaf6329ea54af4771e3820 235 Gene3D G3DSA:3.40.120.10 143 216 1.9E-5 T 23-10-2018 TAM4_1586 a1541a7088aaf6329ea54af4771e3820 235 Gene3D G3DSA:3.40.120.10 3 77 5.9E-6 T 23-10-2018 TAM4_1586 a1541a7088aaf6329ea54af4771e3820 235 SUPERFAMILY SSF53738 7 70 2.47E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_1586 a1541a7088aaf6329ea54af4771e3820 235 SUPERFAMILY SSF53738 127 208 4.0E-9 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TAM4_2157 29adc6d3a218c05fceeb1a7a5ac818db 128 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 119 4.4E-24 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TAM4_1478 24e5ed6788ccfa2385f3b38a928d40d6 288 PIRSF PIRSF016175 7 287 1.2E-124 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related TAM4_1478 24e5ed6788ccfa2385f3b38a928d40d6 288 SUPERFAMILY SSF48239 14 269 1.26E-14 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TAM4_2349 3d1d31deb5138d1c68a76810ee5b46dd 205 Gene3D G3DSA:1.20.58.290 61 181 2.8E-12 T 23-10-2018 TAM4_2349 3d1d31deb5138d1c68a76810ee5b46dd 205 PIRSF PIRSF018747 3 194 8.2E-35 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 TAM4_2349 3d1d31deb5138d1c68a76810ee5b46dd 205 SUPERFAMILY SSF50475 7 182 7.36E-35 T 23-10-2018 TAM4_2349 3d1d31deb5138d1c68a76810ee5b46dd 205 Pfam PF04289 Protein of unknown function (DUF447) 14 182 1.7E-25 T 23-10-2018 IPR007386 Protein of unknown function DUF447 TAM4_2349 3d1d31deb5138d1c68a76810ee5b46dd 205 Gene3D G3DSA:2.30.110.10 13 133 2.8E-12 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TAM4_1737 b26b2badfa4050d4c69d3b3949e1cdd5 450 SUPERFAMILY SSF56731 198 309 2.88E-11 T 23-10-2018 TAM4_1737 b26b2badfa4050d4c69d3b3949e1cdd5 450 SMART SM00493 199 268 1.3E-12 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1737 b26b2badfa4050d4c69d3b3949e1cdd5 450 Hamap MF_00007 DNA primase DnaG [dnaG]. 35 449 36.675 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 TAM4_1737 b26b2badfa4050d4c69d3b3949e1cdd5 450 Pfam PF13662 Toprim domain 200 283 4.6E-13 T 23-10-2018 IPR006171 TOPRIM domain TAM4_1737 b26b2badfa4050d4c69d3b3949e1cdd5 450 Gene3D G3DSA:3.40.1360.10 197 290 8.8E-13 T 23-10-2018 TAM4_59 68d83fe7493f7957c5c0bd9172a07b83 187 Pfam PF06197 Protein of unknown function (DUF998) 13 180 2.7E-23 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TAM4_796 3512127b47c750bca05157d45b30aa7a 223 SUPERFAMILY SSF52540 7 203 1.18E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_796 3512127b47c750bca05157d45b30aa7a 223 Gene3D G3DSA:3.40.50.300 1 222 6.6E-44 T 23-10-2018 TAM4_796 3512127b47c750bca05157d45b30aa7a 223 SMART SM00382 25 198 0.0018 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_796 3512127b47c750bca05157d45b30aa7a 223 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TAM4_796 3512127b47c750bca05157d45b30aa7a 223 Pfam PF00005 ABC transporter 17 151 3.2E-19 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TAM4_8 9efddacbb35f77aa492be06d57494db0 392 Gene3D G3DSA:3.40.50.300 1 207 6.2E-77 T 23-10-2018 TAM4_8 9efddacbb35f77aa492be06d57494db0 392 Gene3D G3DSA:3.40.50.300 211 389 2.7E-53 T 23-10-2018 TAM4_8 9efddacbb35f77aa492be06d57494db0 392 SMART SM00490 252 333 1.4E-36 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_8 9efddacbb35f77aa492be06d57494db0 392 SMART SM00487 20 218 3.5E-63 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_8 9efddacbb35f77aa492be06d57494db0 392 SUPERFAMILY SSF52540 71 350 2.78E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_8 9efddacbb35f77aa492be06d57494db0 392 Pfam PF00271 Helicase conserved C-terminal domain 227 333 1.8E-30 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_8 9efddacbb35f77aa492be06d57494db0 392 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TAM4_8 9efddacbb35f77aa492be06d57494db0 392 Pfam PF00270 DEAD/DEAH box helicase 25 186 4.5E-50 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TAM4_968 60400af1a321f6ea5460d42f38ec5d0b 282 Gene3D G3DSA:1.20.1260.10 52 225 1.3E-70 T 23-10-2018 IPR012347 Ferritin-like TAM4_968 60400af1a321f6ea5460d42f38ec5d0b 282 Pfam PF09968 Uncharacterized protein domain (DUF2202) 57 218 1.4E-67 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TAM4_968 60400af1a321f6ea5460d42f38ec5d0b 282 SUPERFAMILY SSF47240 56 198 9.27E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1579 bf14601500caa0dab0443d789c923d29 462 Pfam PF00271 Helicase conserved C-terminal domain 309 404 6.6E-11 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_1579 bf14601500caa0dab0443d789c923d29 462 Pfam PF04851 Type III restriction enzyme, res subunit 93 231 6.7E-18 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TAM4_1579 bf14601500caa0dab0443d789c923d29 462 Gene3D G3DSA:3.40.50.300 84 261 5.5E-35 T 23-10-2018 TAM4_1579 bf14601500caa0dab0443d789c923d29 462 SUPERFAMILY SSF52540 27 209 1.23E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1579 bf14601500caa0dab0443d789c923d29 462 SMART SM00490 328 406 2.8E-12 T 23-10-2018 IPR001650 Helicase, C-terminal TAM4_1579 bf14601500caa0dab0443d789c923d29 462 SUPERFAMILY SSF52540 136 420 5.53E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1579 bf14601500caa0dab0443d789c923d29 462 SMART SM00487 91 272 4.4E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TAM4_1579 bf14601500caa0dab0443d789c923d29 462 Gene3D G3DSA:3.40.50.300 274 457 2.0E-33 T 23-10-2018 TAM4_1086 dc9b4a122c0abb6670d8ec0c34014800 575 SUPERFAMILY SSF88713 5 219 6.0E-13 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_2181 b6f3ebe9ec1d87831a37cd2338c4b0d7 128 Hamap MF_01223 UPF0212 protein . 1 112 32.903 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TAM4_2181 b6f3ebe9ec1d87831a37cd2338c4b0d7 128 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 1.0E-50 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TAM4_2181 b6f3ebe9ec1d87831a37cd2338c4b0d7 128 PIRSF PIRSF016934 1 124 1.9E-54 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TAM4_2181 b6f3ebe9ec1d87831a37cd2338c4b0d7 128 Pfam PF04475 Protein of unknown function (DUF555) 3 104 1.0E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TAM4_598 e56b83fb6b7eba6fbf92a736d14e2f23 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 28 278 41.386 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 TAM4_598 e56b83fb6b7eba6fbf92a736d14e2f23 279 SUPERFAMILY SSF53335 21 277 4.67E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_598 e56b83fb6b7eba6fbf92a736d14e2f23 279 Gene3D G3DSA:3.30.300.110 21 88 1.6E-29 T 23-10-2018 TAM4_598 e56b83fb6b7eba6fbf92a736d14e2f23 279 Pfam PF02475 Met-10+ like-protein 31 225 1.2E-68 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TAM4_598 e56b83fb6b7eba6fbf92a736d14e2f23 279 Gene3D G3DSA:3.40.50.150 89 279 5.7E-58 T 23-10-2018 TAM4_1642 f17bb6cd1bd569d0eef335b8ae60c06d 107 Pfam PF01909 Nucleotidyltransferase domain 10 57 1.8E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1642 f17bb6cd1bd569d0eef335b8ae60c06d 107 SUPERFAMILY SSF81301 3 105 9.16E-21 T 23-10-2018 TAM4_1642 f17bb6cd1bd569d0eef335b8ae60c06d 107 Gene3D G3DSA:3.30.460.10 1 103 2.4E-18 T 23-10-2018 TAM4_840 244e977592460526130e9333d4ca5b3c 149 SUPERFAMILY SSF88723 6 147 1.12E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_840 244e977592460526130e9333d4ca5b3c 149 Gene3D G3DSA:3.40.50.1010 1 149 3.6E-38 T 23-10-2018 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 Gene3D G3DSA:3.40.50.1860 4 215 1.2E-72 T 23-10-2018 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 224 1.8E-53 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 Gene3D G3DSA:3.40.50.1860 102 211 1.2E-72 T 23-10-2018 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 3.0E-49 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 SUPERFAMILY SSF53681 116 224 3.92E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_1926 775a3cc251c8207055e12608f85f3505 226 SUPERFAMILY SSF53681 1 114 4.25E-27 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_1919 954a4f8caa125f41e99e1bc2a0ec487f 166 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 13 152 1.3E-15 T 23-10-2018 IPR019127 Exosortase TAM4_1919 954a4f8caa125f41e99e1bc2a0ec487f 166 TIGRFAM TIGR04293 archaeo_artF: archaeosortase family protein ArtF 1 166 2.5E-108 T 23-10-2018 IPR027557 Archaeosortase ArtF TAM4_1919 954a4f8caa125f41e99e1bc2a0ec487f 166 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 70 152 1.3E-15 T 23-10-2018 IPR026392 Exosortase/Archaeosortase domain TAM4_307 4550b6f9f78c017013775554ed48b7e9 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_307 4550b6f9f78c017013775554ed48b7e9 334 SUPERFAMILY SSF46548 225 331 1.1E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_307 4550b6f9f78c017013775554ed48b7e9 334 Pfam PF17179 4Fe-4S dicluster domain 228 320 5.2E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_307 4550b6f9f78c017013775554ed48b7e9 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_114 46c602006b82836677ae698bdf780e73 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 279 4.0E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 4.5E-12 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 39 51 4.5E-12 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 146 4.5E-12 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 112 131 4.5E-12 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 112 131 7.6E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 221 7.6E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 149 160 7.6E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 7.6E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 Pfam PF00970 Oxidoreductase FAD-binding domain 13 99 7.7E-5 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TAM4_114 46c602006b82836677ae698bdf780e73 288 SUPERFAMILY SSF52343 96 279 3.14E-30 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_114 46c602006b82836677ae698bdf780e73 288 PIRSF PIRSF006816 3 288 2.3E-79 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TAM4_114 46c602006b82836677ae698bdf780e73 288 Gene3D G3DSA:2.40.30.10 2 100 4.2E-18 T 23-10-2018 TAM4_114 46c602006b82836677ae698bdf780e73 288 SUPERFAMILY SSF63380 2 104 1.72E-20 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TAM4_114 46c602006b82836677ae698bdf780e73 288 Pfam PF00175 Oxidoreductase NAD-binding domain 113 226 1.7E-11 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TAM4_114 46c602006b82836677ae698bdf780e73 288 Gene3D G3DSA:2.10.240.10 246 280 2.5E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TAM4_114 46c602006b82836677ae698bdf780e73 288 Gene3D G3DSA:3.40.50.80 105 245 2.3E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 SUPERFAMILY SSF50249 82 179 2.01E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 SMART SM00316 80 166 1.1E-17 T 23-10-2018 IPR022967 RNA-binding domain, S1 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 Pfam PF00575 S1 RNA binding domain 79 154 2.3E-16 T 23-10-2018 IPR003029 S1 domain GO:0003676 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.6E-19 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 Gene3D G3DSA:3.30.1490.120 1 80 6.9E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 Gene3D G3DSA:2.40.50.140 82 186 2.1E-33 T 23-10-2018 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 SUPERFAMILY SSF88798 1 77 5.62E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TAM4_1013 cae0e2809f28380e40efb051aca00a19 186 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 4.3E-69 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 81 7.2E-29 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 SMART SM01152 7 82 8.2E-37 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 SUPERFAMILY SSF69786 2 91 7.32E-29 T 23-10-2018 IPR036591 YggU-like superfamily TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 93 21.16 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 80 1.6E-25 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TAM4_1794 33ac4dc4b5a33425772566515c4db840 93 Gene3D G3DSA:3.30.1200.10 1 93 2.1E-32 T 23-10-2018 IPR036591 YggU-like superfamily TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 173 7.4E-45 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 SUPERFAMILY SSF55154 1 179 1.8E-36 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 Gene3D G3DSA:2.40.320.10 1 178 6.9E-57 T 23-10-2018 TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 Pfam PF01928 CYTH domain 1 169 6.1E-35 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 7.0E-61 T 23-10-2018 TAM4_820 2fbf6f5f2e973b80934f56597fb75e3f 182 SMART SM01118 1 175 2.6E-25 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TAM4_1884 c58a0c8d3cf138b1324c2b7c91615ed9 188 SUPERFAMILY SSF88697 4 107 9.44E-20 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_1884 c58a0c8d3cf138b1324c2b7c91615ed9 188 SMART SM01022 7 108 1.2E-18 T 23-10-2018 IPR007374 ASCH domain TAM4_1884 c58a0c8d3cf138b1324c2b7c91615ed9 188 Pfam PF04266 ASCH domain 10 108 9.9E-20 T 23-10-2018 IPR007374 ASCH domain TAM4_1595 28881dd6ea9d7d5df5fc8ef0db105c96 224 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 7 30 4.2E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TAM4_1595 28881dd6ea9d7d5df5fc8ef0db105c96 224 Pfam PF01917 Archaebacterial flagellin 9 210 2.1E-52 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_618 ce0fb60f44c49f5e629b8576a34e607a 231 Pfam PF12686 Protein of unknown function (DUF3800) 13 212 7.2E-15 T 23-10-2018 IPR024524 Protein of unknown function DUF3800 TAM4_166 ad1670d4eeb7b542ad4717f558638e07 93 Gene3D G3DSA:3.30.460.10 2 87 6.7E-18 T 23-10-2018 TAM4_166 ad1670d4eeb7b542ad4717f558638e07 93 Pfam PF01909 Nucleotidyltransferase domain 8 58 5.2E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_166 ad1670d4eeb7b542ad4717f558638e07 93 SUPERFAMILY SSF81301 3 91 2.57E-21 T 23-10-2018 TAM4_416 16a6bb16e0860ed4f6739a7891a49181 166 SUPERFAMILY SSF52317 1 165 1.38E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_416 16a6bb16e0860ed4f6739a7891a49181 166 Pfam PF01965 DJ-1/PfpI family 1 163 1.0E-57 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TAM4_416 16a6bb16e0860ed4f6739a7891a49181 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 1.1E-65 T 23-10-2018 IPR006286 Deglycase PfpI TAM4_416 16a6bb16e0860ed4f6739a7891a49181 166 Gene3D G3DSA:3.40.50.880 1 166 7.4E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1976 a230d1370ce08f8ca09605a75654c7e9 157 Hamap MF_00263 UPF0127 protein . 2 116 29.089 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 TAM4_1976 a230d1370ce08f8ca09605a75654c7e9 157 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 1.4E-16 T 23-10-2018 IPR003795 Protein of unknown function DUF192 TAM4_1976 a230d1370ce08f8ca09605a75654c7e9 157 Gene3D G3DSA:2.60.120.1140 1 123 2.3E-12 T 23-10-2018 IPR038695 Saro_0823-like superfamily TAM4_1271 a6f5d244015730367feb0e15ab1a24be 303 Gene3D G3DSA:1.20.81.30 91 210 2.5E-8 T 23-10-2018 TAM4_1271 a6f5d244015730367feb0e15ab1a24be 303 Pfam PF00482 Type II secretion system (T2SS), protein F 105 226 5.2E-17 T 23-10-2018 IPR018076 Type II secretion system F domain TAM4_958 0a43b1af26a5dc58733bfd7511d58c10 256 SUPERFAMILY SSF53335 32 215 2.79E-13 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_958 0a43b1af26a5dc58733bfd7511d58c10 256 Gene3D G3DSA:3.40.50.150 4 193 2.8E-11 T 23-10-2018 TAM4_958 0a43b1af26a5dc58733bfd7511d58c10 256 Pfam PF13649 Methyltransferase domain 47 147 1.8E-6 T 23-10-2018 TAM4_2124 fa21c5fb5dc42ebb898c7e2864a8540c 177 Gene3D G3DSA:3.40.630.30 2 173 3.6E-48 T 23-10-2018 TAM4_2124 fa21c5fb5dc42ebb898c7e2864a8540c 177 SUPERFAMILY SSF55729 2 174 2.75E-44 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_2124 fa21c5fb5dc42ebb898c7e2864a8540c 177 Pfam PF13302 Acetyltransferase (GNAT) domain 16 149 7.0E-31 T 23-10-2018 IPR000182 GNAT domain TAM4_709 eb7d4c50a3adf75eeafb8f81f464fdb7 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_709 eb7d4c50a3adf75eeafb8f81f464fdb7 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.311 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_709 eb7d4c50a3adf75eeafb8f81f464fdb7 67 Gene3D G3DSA:1.10.60.20 1 62 5.2E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_709 eb7d4c50a3adf75eeafb8f81f464fdb7 67 Pfam PF00833 Ribosomal S17 1 64 1.1E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_709 eb7d4c50a3adf75eeafb8f81f464fdb7 67 SUPERFAMILY SSF116820 1 60 1.44E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_602 6e73fcc5249209516de5857a589d9bce 379 Pfam PF05763 Protein of unknown function (DUF835) 229 364 2.1E-32 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 Gene3D G3DSA:3.40.50.10300 187 402 2.2E-71 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 SUPERFAMILY SSF52507 18 217 9.68E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 397 1.4E-129 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 SUPERFAMILY SSF102645 180 401 3.92E-67 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 Pfam PF02441 Flavoprotein 19 188 9.1E-42 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 Gene3D G3DSA:3.40.50.1950 15 186 1.2E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TAM4_1495 1877771d949568a4a7b2122568a99f30 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 372 9.3E-58 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TAM4_1213 f8b898e395247bea9f61ccb2e7800207 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 115 2.9E-26 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TAM4_1518 e4b10ff3dfe25a42256512a36bd2ee6d 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 47 3.6E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1518 e4b10ff3dfe25a42256512a36bd2ee6d 83 SMART SM00966 4 49 3.0E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1518 e4b10ff3dfe25a42256512a36bd2ee6d 83 SUPERFAMILY SSF89447 1 47 3.49E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_1518 e4b10ff3dfe25a42256512a36bd2ee6d 83 Gene3D G3DSA:2.10.260.10 1 42 3.5E-15 T 23-10-2018 TAM4_1518 e4b10ff3dfe25a42256512a36bd2ee6d 83 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 45 1.7E-18 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_443 35c3f247e21bde72424a9882c16710cd 88 SUPERFAMILY SSF46785 1 85 1.12E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_443 35c3f247e21bde72424a9882c16710cd 88 Gene3D G3DSA:2.20.28.10 1 86 2.3E-30 T 23-10-2018 TAM4_1503 6c9eca75554e36cbd53608b98715a6b3 360 Gene3D G3DSA:3.90.550.10 2 248 1.5E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1503 6c9eca75554e36cbd53608b98715a6b3 360 SUPERFAMILY SSF53448 5 227 1.35E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_1503 6c9eca75554e36cbd53608b98715a6b3 360 Pfam PF04138 GtrA-like protein 244 359 4.0E-27 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TAM4_1503 6c9eca75554e36cbd53608b98715a6b3 360 Pfam PF00535 Glycosyl transferase family 2 10 177 6.3E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_2411 9733a6d846b676be4f266319b9c46b06 83 Gene3D G3DSA:2.30.30.30 2 83 9.7E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TAM4_2411 9733a6d846b676be4f266319b9c46b06 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 27.667 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 TAM4_2411 9733a6d846b676be4f266319b9c46b06 83 Pfam PF01929 Ribosomal protein L14 44 81 1.3E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_2411 9733a6d846b676be4f266319b9c46b06 83 SUPERFAMILY SSF50104 2 80 6.62E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TAM4_232 0756f83406d1b45be87442188d2328a8 130 SUPERFAMILY SSF143870 11 103 1.31E-16 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TAM4_232 0756f83406d1b45be87442188d2328a8 130 Gene3D G3DSA:3.30.2380.10 2 130 2.4E-35 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TAM4_1128 f2ffe9ef55d1c47b6bd79e6408763c2d 78 Gene3D G3DSA:2.10.260.10 2 42 1.6E-16 T 23-10-2018 TAM4_1128 f2ffe9ef55d1c47b6bd79e6408763c2d 78 SUPERFAMILY SSF89447 1 66 1.26E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily TAM4_1128 f2ffe9ef55d1c47b6bd79e6408763c2d 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 44 8.8E-17 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1128 f2ffe9ef55d1c47b6bd79e6408763c2d 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 44 2.8E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1128 f2ffe9ef55d1c47b6bd79e6408763c2d 78 SMART SM00966 4 49 7.1E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 Gene3D G3DSA:3.30.540.10 5 143 5.4E-36 T 23-10-2018 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 Gene3D G3DSA:3.40.190.80 146 258 2.0E-27 T 23-10-2018 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.5E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 168 189 1.5E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.5E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 1.5E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 1.5E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 SUPERFAMILY SSF56655 11 252 1.44E-54 T 23-10-2018 TAM4_1800 9dc7b93bfb13721514c3e1d2fbf90103 261 Pfam PF00459 Inositol monophosphatase family 12 258 8.5E-37 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 SUPERFAMILY SSF54843 8 153 3.14E-47 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 Gene3D G3DSA:3.90.470.10 6 156 9.6E-53 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 1.4E-34 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.81 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_37 814aedb0311f9c17adeaaa8efa2edb19 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 2.0E-67 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1148 7dc586badf982e1fa6dfa0624e4e493e 171 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 151 170 3.8E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1980 9f384d84964f091ea09a24a1572376a1 183 Gene3D G3DSA:1.20.1260.10 4 160 4.4E-62 T 23-10-2018 IPR012347 Ferritin-like TAM4_1980 9f384d84964f091ea09a24a1572376a1 183 SUPERFAMILY SSF47240 3 159 7.0E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1980 9f384d84964f091ea09a24a1572376a1 183 PIRSF PIRSF018063 1 168 1.7E-67 T 23-10-2018 IPR014490 DNA-binding protein from starved cells-like TAM4_1980 9f384d84964f091ea09a24a1572376a1 183 Pfam PF00210 Ferritin-like domain 21 160 1.0E-21 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TAM4_1758 537a39a046395ba94122b9a9199cdae9 453 Pfam PF07690 Major Facilitator Superfamily 12 261 3.2E-33 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1758 537a39a046395ba94122b9a9199cdae9 453 Pfam PF07690 Major Facilitator Superfamily 282 433 2.2E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1758 537a39a046395ba94122b9a9199cdae9 453 Gene3D G3DSA:1.20.1250.20 4 273 3.5E-35 T 23-10-2018 TAM4_1758 537a39a046395ba94122b9a9199cdae9 453 Gene3D G3DSA:1.20.1250.20 274 444 9.5E-18 T 23-10-2018 TAM4_1758 537a39a046395ba94122b9a9199cdae9 453 SUPERFAMILY SSF103473 8 438 2.35E-59 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_325 4829fd73f09136cc43a6c933a91bbd5f 158 Pfam PF01230 HIT domain 10 100 9.6E-25 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TAM4_325 4829fd73f09136cc43a6c933a91bbd5f 158 Gene3D G3DSA:3.30.428.10 1 147 2.1E-40 T 23-10-2018 IPR036265 HIT-like superfamily TAM4_325 4829fd73f09136cc43a6c933a91bbd5f 158 SUPERFAMILY SSF54197 2 148 5.88E-38 T 23-10-2018 IPR036265 HIT-like superfamily TAM4_325 4829fd73f09136cc43a6c933a91bbd5f 158 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site TAM4_122 275a57e6a2b2d36f476f5a890c16786e 195 Gene3D G3DSA:3.40.50.150 5 193 3.0E-49 T 23-10-2018 TAM4_122 275a57e6a2b2d36f476f5a890c16786e 195 Pfam PF05175 Methyltransferase small domain 28 191 1.1E-44 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TAM4_122 275a57e6a2b2d36f476f5a890c16786e 195 SUPERFAMILY SSF53335 6 190 3.29E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_1425 c1d43d87f42b2476e2dda6574948f060 130 Gene3D G3DSA:1.20.120.330 3 123 1.1E-33 T 23-10-2018 TAM4_1425 c1d43d87f42b2476e2dda6574948f060 130 SUPERFAMILY SSF81593 8 121 7.85E-6 T 23-10-2018 TAM4_1425 c1d43d87f42b2476e2dda6574948f060 130 Pfam PF05168 HEPN domain 4 120 1.7E-24 T 23-10-2018 IPR007842 HEPN domain TAM4_1320 c71a3f7fb88f12597e92c9d178ed677a 253 Gene3D G3DSA:3.40.50.300 3 253 9.4E-62 T 23-10-2018 TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 Gene3D G3DSA:3.40.1350.10 2 129 1.9E-39 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 PIRSF PIRSF004985 1 129 7.6E-41 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 8.4E-31 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 126 6.0E-31 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 SUPERFAMILY SSF52980 3 95 9.25E-27 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_584 360fd6fc8ebc7cb03463d8b40c5836a8 137 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 126 38.725 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TAM4_1250 908867ea24c308c14cb0fd77bd2bb35e 183 Pfam PF04407 Protein of unknown function (DUF531) 1 169 2.3E-77 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TAM4_1250 908867ea24c308c14cb0fd77bd2bb35e 183 PIRSF PIRSF006006 1 178 2.0E-84 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TAM4_1917 eb4c609526a52f49f84d1a476eaec83d 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.962 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TAM4_1917 eb4c609526a52f49f84d1a476eaec83d 255 Pfam PF03746 LamB/YcsF family 3 241 1.0E-107 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TAM4_1917 eb4c609526a52f49f84d1a476eaec83d 255 SUPERFAMILY SSF88713 1 252 3.11E-106 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TAM4_1917 eb4c609526a52f49f84d1a476eaec83d 255 Gene3D G3DSA:3.20.20.370 1 255 2.7E-114 T 23-10-2018 TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 Gene3D G3DSA:1.10.3720.10 4 261 1.0E-61 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 Gene3D G3DSA:1.10.3720.10 282 537 2.7E-48 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 SUPERFAMILY SSF161098 285 533 4.03E-47 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 SUPERFAMILY SSF161098 4 254 2.06E-52 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 357 531 8.7E-8 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1694 c1d4516f4689acce14d5a1ece27c7e88 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 250 3.3E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_487 f0b2ec7b9e0710320afd109a45070a5d 333 SUPERFAMILY SSF161098 94 320 1.08E-18 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_487 f0b2ec7b9e0710320afd109a45070a5d 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 3.8E-44 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1326 547938d0c79c58d42e8316e11f121323 152 SMART SM00318 25 151 1.9E-6 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TAM4_1326 547938d0c79c58d42e8316e11f121323 152 SUPERFAMILY SSF50199 27 144 3.79E-21 T 23-10-2018 TAM4_1326 547938d0c79c58d42e8316e11f121323 152 Gene3D G3DSA:2.40.50.90 24 148 9.0E-20 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily TAM4_1326 547938d0c79c58d42e8316e11f121323 152 Pfam PF00565 Staphylococcal nuclease homologue 55 142 1.2E-9 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TAM4_530 633ff6971947fdb12310ac079682db33 267 Pfam PF13630 SdpI/YhfL protein family 27 88 7.0E-9 T 23-10-2018 IPR025962 SdpI/YhfL protein family TAM4_530 633ff6971947fdb12310ac079682db33 267 Pfam PF07853 Protein of unknown function (DUF1648) 134 180 3.8E-16 T 23-10-2018 IPR012867 Domain of unknown function DUF1648 TAM4_530 633ff6971947fdb12310ac079682db33 267 Pfam PF11239 Protein of unknown function (DUF3040) 190 254 2.2E-5 T 23-10-2018 IPR021401 Protein of unknown function DUF3040 TAM4_1345 6a65efd938d9a03d9beb7c3affea7120 215 Pfam PF01865 Protein of unknown function DUF47 7 211 1.9E-45 T 23-10-2018 IPR018445 Putative phosphate transport regulator TAM4_1345 6a65efd938d9a03d9beb7c3affea7120 215 SUPERFAMILY SSF109755 19 209 5.41E-9 T 23-10-2018 TAM4_1345 6a65efd938d9a03d9beb7c3affea7120 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 12 214 1.1E-43 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TAM4_1345 6a65efd938d9a03d9beb7c3affea7120 215 Gene3D G3DSA:1.20.58.220 2 211 9.5E-51 T 23-10-2018 IPR038078 PhoU-like domain superfamily TAM4_1350 23452d70db73fa239cb1575a59c80e3b 80 Pfam PF03683 Uncharacterised protein family (UPF0175) 18 75 4.2E-22 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 TAM4_2012 e9d07a87745022d3423e10519233197b 346 PRINTS PR00164 ABC-2 type transport system membrane protein signature 227 251 2.0E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TAM4_2012 e9d07a87745022d3423e10519233197b 346 PRINTS PR00164 ABC-2 type transport system membrane protein signature 264 283 2.0E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TAM4_2012 e9d07a87745022d3423e10519233197b 346 PRINTS PR00164 ABC-2 type transport system membrane protein signature 284 303 2.0E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TAM4_2012 e9d07a87745022d3423e10519233197b 346 Pfam PF01061 ABC-2 type transporter 115 307 2.2E-14 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TAM4_507 c0b01250a09dd5d8d8662d70b9af7a76 131 SUPERFAMILY SSF141322 68 130 1.96E-11 T 23-10-2018 TAM4_507 c0b01250a09dd5d8d8662d70b9af7a76 131 Pfam PF01957 NfeD-like C-terminal, partner-binding 22 131 1.8E-16 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TAM4_507 c0b01250a09dd5d8d8662d70b9af7a76 131 Gene3D G3DSA:2.40.50.140 69 131 7.1E-20 T 23-10-2018 TAM4_1652 39a013689b26526ede43a3c38be0de66 74 Gene3D G3DSA:3.30.310.50 1 74 2.8E-23 T 23-10-2018 TAM4_1652 39a013689b26526ede43a3c38be0de66 74 Pfam PF09341 Transcription factor Pcc1 2 72 4.5E-12 T 23-10-2018 IPR015419 CTAG/Pcc1 family TAM4_850 3ed9f5938227199d893eade9f58f53f7 270 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 34 230 1.9E-46 T 23-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 TAM4_850 3ed9f5938227199d893eade9f58f53f7 270 Pfam PF02361 Cobalt transport protein 31 234 1.7E-34 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TAM4_827 3da30faf58f483b76e96b55b9a8730a9 135 Pfam PF02566 OsmC-like protein 32 127 1.1E-16 T 23-10-2018 IPR003718 OsmC/Ohr family TAM4_827 3da30faf58f483b76e96b55b9a8730a9 135 SUPERFAMILY SSF82784 8 133 1.16E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TAM4_827 3da30faf58f483b76e96b55b9a8730a9 135 Gene3D G3DSA:3.30.300.20 6 133 3.7E-34 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TAM4_1488 25d96b2a31a6c7d7caaf4e30fbf8a7e5 142 Hamap MF_01222 Protein archease. 2 142 41.425 T 23-10-2018 IPR022952 Archease, archaea TAM4_1488 25d96b2a31a6c7d7caaf4e30fbf8a7e5 142 SUPERFAMILY SSF69819 2 142 1.96E-48 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TAM4_1488 25d96b2a31a6c7d7caaf4e30fbf8a7e5 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 6.0E-48 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TAM4_1488 25d96b2a31a6c7d7caaf4e30fbf8a7e5 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 3.6E-46 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TAM4_1488 25d96b2a31a6c7d7caaf4e30fbf8a7e5 142 Gene3D G3DSA:3.55.10.10 1 142 1.4E-52 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TAM4_1212 f8badf8510f5a99aa4f7a594efb96d43 64 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 2 64 4.6E-26 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 TAM4_425 2a0f8914997765c6b25b9af76abfa80e 122 SUPERFAMILY SSF46785 17 116 2.12E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_425 2a0f8914997765c6b25b9af76abfa80e 122 Pfam PF03965 Penicillinase repressor 19 111 9.4E-17 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 TAM4_425 2a0f8914997765c6b25b9af76abfa80e 122 Gene3D G3DSA:1.10.10.10 19 85 4.6E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_246 944dbfc2c5dcdd31eaac654b1f1d1260 140 Pfam PF13470 PIN domain 1 98 2.2E-9 T 23-10-2018 IPR002716 PIN domain TAM4_246 944dbfc2c5dcdd31eaac654b1f1d1260 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 96 6.8E-8 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TAM4_665 db44d7c4a7702a3353589eacf07dee3f 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 1.2E-62 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TAM4_665 db44d7c4a7702a3353589eacf07dee3f 310 Gene3D G3DSA:3.90.25.10 172 300 1.6E-106 T 23-10-2018 TAM4_665 db44d7c4a7702a3353589eacf07dee3f 310 Gene3D G3DSA:3.40.50.720 6 236 1.6E-106 T 23-10-2018 TAM4_665 db44d7c4a7702a3353589eacf07dee3f 310 SUPERFAMILY SSF51735 1 307 2.01E-100 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_775 505abb1747cc92b3397e99111db66c5f 180 Pfam PF04019 Protein of unknown function (DUF359) 53 174 1.3E-38 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TAM4_775 505abb1747cc92b3397e99111db66c5f 180 PIRSF PIRSF006533 5 178 8.5E-54 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TAM4_775 505abb1747cc92b3397e99111db66c5f 180 Hamap MF_00590 UPF0218 protein . 9 176 30.068 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TAM4_77 47a9fae26e542e4db2ffb8ab11514632 316 PIRSF PIRSF004884 1 316 2.2E-75 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TAM4_77 47a9fae26e542e4db2ffb8ab11514632 316 Gene3D G3DSA:3.30.230.10 12 136 1.6E-5 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TAM4_77 47a9fae26e542e4db2ffb8ab11514632 316 SUPERFAMILY SSF54211 2 138 2.81E-12 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TAM4_77 47a9fae26e542e4db2ffb8ab11514632 316 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 3 313 2.1E-43 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TAM4_1801 13c6b30d2eec771b562e654363dc6265 102 Pfam PF11419 Protein of unknown function (DUF3194) 11 93 4.5E-28 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 TAM4_1801 13c6b30d2eec771b562e654363dc6265 102 Gene3D G3DSA:3.30.300.100 1 102 8.1E-38 T 23-10-2018 IPR035954 MTH677-like superfamily TAM4_1125 02fc3514f199808cedfd90962159a591 499 Gene3D G3DSA:1.10.1370.30 1 499 9.2E-199 T 23-10-2018 TAM4_1125 02fc3514f199808cedfd90962159a591 499 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 498 1.8E-106 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 SUPERFAMILY SSF55486 8 499 1.36E-116 T 23-10-2018 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PIRSF PIRSF006615 5 499 1.4E-199 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 450 468 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_1125 02fc3514f199808cedfd90962159a591 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 3.5E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TAM4_2046 8518b1c876c2180daeed0c5794dc03be 178 Gene3D G3DSA:3.90.320.10 18 178 3.1E-9 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TAM4_2046 8518b1c876c2180daeed0c5794dc03be 178 Pfam PF01930 Domain of unknown function DUF83 21 177 8.7E-54 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 TAM4_2046 8518b1c876c2180daeed0c5794dc03be 178 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 20 177 1.6E-24 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 TAM4_1998 1fdb32788469ecf5c3f6b5381a16c8cc 153 Pfam PF00583 Acetyltransferase (GNAT) family 25 108 3.0E-13 T 23-10-2018 IPR000182 GNAT domain TAM4_1998 1fdb32788469ecf5c3f6b5381a16c8cc 153 Gene3D G3DSA:3.40.630.30 4 151 3.7E-25 T 23-10-2018 TAM4_1998 1fdb32788469ecf5c3f6b5381a16c8cc 153 SUPERFAMILY SSF55729 13 151 6.42E-22 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_468 f821e78e654fa2e1159075442baa9e27 108 SUPERFAMILY SSF88723 3 98 4.21E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_468 f821e78e654fa2e1159075442baa9e27 108 Gene3D G3DSA:3.40.50.1010 1 106 5.6E-11 T 23-10-2018 TAM4_342 84940b513d69514f600f0b5a87c94b3b 58 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 2 58 1.0E-25 T 23-10-2018 IPR020199 Uncharacterised protein family PYRAB06030 TAM4_2058 d0b70739150692ea0b5f54502273e787 229 Gene3D G3DSA:3.90.320.10 8 221 4.9E-22 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TAM4_229 e9ae24498cc4309109869c8df0193a93 393 Gene3D G3DSA:3.40.50.2000 173 374 2.7E-31 T 23-10-2018 TAM4_229 e9ae24498cc4309109869c8df0193a93 393 SUPERFAMILY SSF53756 27 389 3.77E-40 T 23-10-2018 TAM4_229 e9ae24498cc4309109869c8df0193a93 393 Pfam PF00534 Glycosyl transferases group 1 198 369 3.3E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TAM4_229 e9ae24498cc4309109869c8df0193a93 393 Gene3D G3DSA:3.40.50.2000 28 384 2.7E-31 T 23-10-2018 TAM4_882 2b39380533252f1eb6825122687694b8 438 PIRSF PIRSF009445 1 434 8.7E-194 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TAM4_882 2b39380533252f1eb6825122687694b8 438 Gene3D G3DSA:3.40.50.300 131 319 4.2E-7 T 23-10-2018 TAM4_882 2b39380533252f1eb6825122687694b8 438 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 433 49.422 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TAM4_1918 eeb6135bc50c331fd30490ff120f297f 707 SUPERFAMILY SSF52980 17 129 1.39E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_1918 eeb6135bc50c331fd30490ff120f297f 707 Pfam PF04471 Restriction endonuclease 9 124 1.5E-13 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 Hamap MF_00325 DNA polymerase II small subunit [polB]. 1 641 32.353 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 Gene3D G3DSA:2.40.50.140 282 357 6.0E-6 T 23-10-2018 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 Gene3D G3DSA:3.60.21.50 369 623 1.2E-24 T 23-10-2018 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 PIRSF PIRSF000803 20 648 3.2E-177 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 Gene3D G3DSA:1.10.8.800 1 66 7.7E-25 T 23-10-2018 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 385 589 3.6E-16 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 TAM4_2440 8ebc3172aa112b0544e936a8a29685e8 651 SUPERFAMILY SSF56300 385 612 7.08E-21 T 23-10-2018 TAM4_1995 3eb32e336bf965fa705ba2fe3bbd6743 347 SUPERFAMILY SSF51445 37 339 1.16E-26 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TAM4_1995 3eb32e336bf965fa705ba2fe3bbd6743 347 Gene3D G3DSA:3.20.20.80 48 335 7.4E-26 T 23-10-2018 TAM4_1995 3eb32e336bf965fa705ba2fe3bbd6743 347 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 89 276 2.2E-9 T 23-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 TAM4_1343 d177712511ab457b390525ef52e2ad8f 164 Gene3D G3DSA:2.40.50.100 97 163 7.8E-31 T 23-10-2018 TAM4_1343 d177712511ab457b390525ef52e2ad8f 164 PIRSF PIRSF019115 1 164 1.5E-67 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TAM4_1343 d177712511ab457b390525ef52e2ad8f 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 2 163 1.1E-52 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TAM4_99 c5562dd4d2c68b3bdb496a0171d3ad59 414 Pfam PF00374 Nickel-dependent hydrogenase 234 410 4.0E-17 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TAM4_99 c5562dd4d2c68b3bdb496a0171d3ad59 414 Pfam PF00374 Nickel-dependent hydrogenase 39 121 9.0E-16 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TAM4_99 c5562dd4d2c68b3bdb496a0171d3ad59 414 Gene3D G3DSA:1.10.645.10 2 410 1.9E-98 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_99 c5562dd4d2c68b3bdb496a0171d3ad59 414 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 401 410 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TAM4_99 c5562dd4d2c68b3bdb496a0171d3ad59 414 SUPERFAMILY SSF56762 7 410 4.58E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_797 732810d69126e53cf7485f4921b31d70 215 Pfam PF00149 Calcineurin-like phosphoesterase 4 177 5.3E-18 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_797 732810d69126e53cf7485f4921b31d70 215 SUPERFAMILY SSF56300 2 212 1.47E-68 T 23-10-2018 TAM4_797 732810d69126e53cf7485f4921b31d70 215 Gene3D G3DSA:3.60.21.10 2 214 9.0E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_1937 b7ef79dbb7fcb7132b302225a89f0294 68 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 7.0E-15 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 TAM4_1438 a8dc5d4637ed765ab11b047930ed227d 440 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 8 415 1.5E-50 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TAM4_1872 fb30646bd46483b7de7d9060e0d514c2 177 Pfam PF13238 AAA domain 3 116 2.2E-21 T 23-10-2018 TAM4_1872 fb30646bd46483b7de7d9060e0d514c2 177 Gene3D G3DSA:3.40.50.300 1 177 5.2E-59 T 23-10-2018 TAM4_1872 fb30646bd46483b7de7d9060e0d514c2 177 SUPERFAMILY SSF52540 1 154 4.55E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1872 fb30646bd46483b7de7d9060e0d514c2 177 Hamap MF_00039 Putative adenylate kinase. 1 160 25.426 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TAM4_521 5a4d6d877827e39bdd6af8af575dd46f 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 2.2E-58 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TAM4_834 ea8dd95f8054f5a0e7bd4b8cb2808b5a 371 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 361 4.8E-45 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 52.261 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 Gene3D G3DSA:3.30.70.2510 162 275 3.4E-31 T 23-10-2018 TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 Gene3D G3DSA:3.30.70.3190 276 384 7.4E-30 T 23-10-2018 TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 SUPERFAMILY SSF55120 272 383 1.01E-11 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 384 6.7E-146 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TAM4_636 db76eac907bcfa6deba262189ab4a7c0 385 Pfam PF02926 THUMP domain 51 162 1.1E-12 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TAM4_282 71e2d7f957b5ba142537ec884c82ea8d 351 Pfam PF13641 Glycosyltransferase like family 2 116 275 2.7E-9 T 23-10-2018 TAM4_282 71e2d7f957b5ba142537ec884c82ea8d 351 SUPERFAMILY SSF53448 2 330 6.7E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TAM4_282 71e2d7f957b5ba142537ec884c82ea8d 351 Pfam PF00535 Glycosyl transferase family 2 6 70 7.5E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TAM4_72 ea5b6c498329651eb2bb9b99248781b0 174 Pfam PF04266 ASCH domain 6 108 4.6E-7 T 23-10-2018 IPR007374 ASCH domain TAM4_72 ea5b6c498329651eb2bb9b99248781b0 174 SMART SM01022 5 125 2.0E-7 T 23-10-2018 IPR007374 ASCH domain TAM4_72 ea5b6c498329651eb2bb9b99248781b0 174 SUPERFAMILY SSF88697 3 143 2.32E-15 T 23-10-2018 IPR015947 PUA-like superfamily TAM4_779 62a606f7dd9220435ebc6659b5c38022 143 Gene3D G3DSA:3.40.50.1010 1 128 1.3E-6 T 23-10-2018 TAM4_779 62a606f7dd9220435ebc6659b5c38022 143 SUPERFAMILY SSF88723 3 125 2.33E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_779 62a606f7dd9220435ebc6659b5c38022 143 Pfam PF10130 PIN domain 4 119 3.8E-17 T 23-10-2018 IPR002716 PIN domain TAM4_855 49abe3aa3e18c298ddd7d8534f015fb5 92 SUPERFAMILY SSF82649 4 86 8.89E-12 T 23-10-2018 TAM4_855 49abe3aa3e18c298ddd7d8534f015fb5 92 Gene3D G3DSA:3.30.390.50 1 88 1.3E-25 T 23-10-2018 TAM4_855 49abe3aa3e18c298ddd7d8534f015fb5 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 57 1.1E-8 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 TAM4_1228 de9615085c1ac19d72d27c2e88787cc8 156 Gene3D G3DSA:3.10.50.80 2 155 9.1E-54 T 23-10-2018 TAM4_1228 de9615085c1ac19d72d27c2e88787cc8 156 SUPERFAMILY SSF54534 2 151 1.53E-46 T 23-10-2018 TAM4_1228 de9615085c1ac19d72d27c2e88787cc8 156 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 8.7E-20 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TAM4_505 d8282121c434bc7acda8f1896f02935e 381 Gene3D G3DSA:3.40.50.2000 2 206 7.4E-39 T 23-10-2018 TAM4_505 d8282121c434bc7acda8f1896f02935e 381 Pfam PF13439 Glycosyltransferase Family 4 18 184 9.7E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TAM4_505 d8282121c434bc7acda8f1896f02935e 381 SUPERFAMILY SSF53756 5 375 1.49E-94 T 23-10-2018 TAM4_505 d8282121c434bc7acda8f1896f02935e 381 Pfam PF00534 Glycosyl transferases group 1 193 351 6.2E-43 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TAM4_505 d8282121c434bc7acda8f1896f02935e 381 Gene3D G3DSA:3.40.50.2000 207 357 3.2E-46 T 23-10-2018 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 PIRSF PIRSF005622 1 369 3.6E-143 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 5 366 9.5E-133 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 Gene3D G3DSA:3.40.50.11750 17 262 4.5E-110 T 23-10-2018 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 Pfam PF01924 Hydrogenase formation hypA family 12 366 3.0E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 Gene3D G3DSA:3.40.50.11740 61 302 4.5E-110 T 23-10-2018 TAM4_1331 3d56aa276e10415493547e2a819199a1 369 Gene3D G3DSA:1.10.10.2140 317 369 2.2E-25 T 23-10-2018 TAM4_147 ddfc99f7bcad1ca3c412063d6377ffab 395 SUPERFAMILY SSF48452 121 330 3.79E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_147 ddfc99f7bcad1ca3c412063d6377ffab 395 SMART SM00028 10 43 220.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_147 ddfc99f7bcad1ca3c412063d6377ffab 395 SMART SM00028 127 160 33.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_147 ddfc99f7bcad1ca3c412063d6377ffab 395 SMART SM00028 289 322 4.7 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TAM4_147 ddfc99f7bcad1ca3c412063d6377ffab 395 Gene3D G3DSA:1.25.40.10 88 375 4.1E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_2076 1fee72f96e07a4cada8436f5dfd4e870 207 Gene3D G3DSA:3.40.50.360 3 105 1.1E-12 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_2076 1fee72f96e07a4cada8436f5dfd4e870 207 Pfam PF12724 Flavodoxin domain 4 143 1.1E-15 T 23-10-2018 IPR026816 Flavodoxin domain TAM4_2076 1fee72f96e07a4cada8436f5dfd4e870 207 SUPERFAMILY SSF52218 2 149 6.85E-17 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 Pfam PF13353 4Fe-4S single cluster domain 73 166 1.1E-6 T 23-10-2018 TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 341 8.7E-113 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 PIRSF PIRSF004869 1 313 2.9E-97 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 Pfam PF04055 Radical SAM superfamily 78 235 6.2E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 Gene3D G3DSA:3.20.20.70 62 286 4.4E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TAM4_924 5522ba9bc9b1c5c63ca8a1185ca58476 349 SUPERFAMILY SSF102114 58 315 2.88E-36 T 23-10-2018 TAM4_578 b7f75e9627fbda5bdad5729bdbe77610 111 ProDom PD074023 BIOSYNTHESIS COBALAMIN CBIM COBALT PRECURSOR SIGNAL NICKEL MEMBRANE ABC PROTEIN 7 107 2.0E-26 T 23-10-2018 IPR020486 Probable fused nickel transport protein LarMN-like TAM4_578 b7f75e9627fbda5bdad5729bdbe77610 111 Pfam PF13190 PDGLE domain 30 100 2.5E-8 T 23-10-2018 IPR025937 PDGLE domain TAM4_346 a06d81f1c8b22da4dce06f2f04ac2ef6 394 Pfam PF00266 Aminotransferase class-V 81 235 2.1E-22 T 23-10-2018 IPR000192 Aminotransferase class V domain TAM4_346 a06d81f1c8b22da4dce06f2f04ac2ef6 394 Gene3D G3DSA:3.90.1150.10 13 381 4.4E-63 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TAM4_346 a06d81f1c8b22da4dce06f2f04ac2ef6 394 SUPERFAMILY SSF53383 1 391 7.71E-61 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TAM4_346 a06d81f1c8b22da4dce06f2f04ac2ef6 394 Gene3D G3DSA:3.40.640.10 25 298 4.4E-63 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 185 496 1.7E-93 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 496 37.677 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 Gene3D G3DSA:1.10.10.10 6 80 2.6E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 SUPERFAMILY SSF46785 71 143 2.26E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 Pfam PF01409 tRNA synthetases class II core domain (F) 223 494 6.3E-83 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 SUPERFAMILY SSF55681 223 496 4.98E-60 T 23-10-2018 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 Gene3D G3DSA:3.30.930.10 191 499 6.2E-91 T 23-10-2018 TAM4_1935 8487cf3a2ca57e8941485f61706391d4 499 SUPERFAMILY SSF46785 11 83 5.09E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1838 ec4fccdbee6fa1f409eea68dfbef1103 223 Gene3D G3DSA:3.40.50.2020 1 218 1.2E-58 T 23-10-2018 TAM4_1838 ec4fccdbee6fa1f409eea68dfbef1103 223 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 41.213 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TAM4_1838 ec4fccdbee6fa1f409eea68dfbef1103 223 SUPERFAMILY SSF53271 13 217 7.21E-56 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TAM4_1838 ec4fccdbee6fa1f409eea68dfbef1103 223 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 1.6E-74 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TAM4_1838 ec4fccdbee6fa1f409eea68dfbef1103 223 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 9.3E-50 T 23-10-2018 TAM4_1080 8bc4338996a9304bf4792126b756336f 61 SMART SM00355 17 40 0.0016 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TAM4_1080 8bc4338996a9304bf4792126b756336f 61 SUPERFAMILY SSF57667 12 41 6.4E-6 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily TAM4_1080 8bc4338996a9304bf4792126b756336f 61 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 19 40 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TAM4_1080 8bc4338996a9304bf4792126b756336f 61 Pfam PF00096 Zinc finger, C2H2 type 17 40 6.5E-6 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TAM4_33 f2eba609d117e39d5d268502578e31a5 153 SUPERFAMILY SSF51230 74 152 6.28E-27 T 23-10-2018 IPR011053 Single hybrid motif TAM4_33 f2eba609d117e39d5d268502578e31a5 153 Gene3D G3DSA:2.40.50.100 80 153 2.3E-30 T 23-10-2018 TAM4_33 f2eba609d117e39d5d268502578e31a5 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TAM4_33 f2eba609d117e39d5d268502578e31a5 153 Pfam PF00364 Biotin-requiring enzyme 86 152 3.0E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TAM4_1661 f69100932a3cc76e4c3a96a5cd69c59b 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 1.5E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TAM4_1661 f69100932a3cc76e4c3a96a5cd69c59b 85 SUPERFAMILY SSF47598 4 41 5.56E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TAM4_845 779b0d536270ca84cbaebf824b8f9858 139 Pfam PF10130 PIN domain 4 120 1.1E-21 T 23-10-2018 IPR002716 PIN domain TAM4_845 779b0d536270ca84cbaebf824b8f9858 139 Gene3D G3DSA:3.40.50.1010 1 127 7.6E-7 T 23-10-2018 TAM4_845 779b0d536270ca84cbaebf824b8f9858 139 SUPERFAMILY SSF88723 2 129 2.8E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 SUPERFAMILY SSF55785 324 422 1.23E-8 T 23-10-2018 IPR035965 PAS domain superfamily TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 Pfam PF04282 Family of unknown function (DUF438) 15 80 1.1E-23 T 23-10-2018 IPR007380 Domain of unknown function DUF438 TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 Pfam PF13596 PAS domain 326 429 2.0E-22 T 23-10-2018 TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 Gene3D G3DSA:3.30.450.20 307 442 8.4E-45 T 23-10-2018 TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 Pfam PF01814 Hemerythrin HHE cation binding domain 101 233 1.4E-15 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TAM4_2100 6a623fa06d4de002b517373c45a9ed74 446 Gene3D G3DSA:1.20.120.520 87 306 2.8E-53 T 23-10-2018 TAM4_431 1a804c7a5715fef86c6c0af1a2f100fe 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 1.7E-42 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 TAM4_431 1a804c7a5715fef86c6c0af1a2f100fe 105 Pfam PF00428 60s Acidic ribosomal protein 16 104 1.9E-19 T 23-10-2018 TAM4_431 1a804c7a5715fef86c6c0af1a2f100fe 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 14.664 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_431 1a804c7a5715fef86c6c0af1a2f100fe 105 Gene3D G3DSA:1.10.10.1410 1 58 1.2E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1707 8dda9b9d1b0f9cf7322bc58254d4d4df 365 Pfam PF01882 Protein of unknown function DUF58 141 224 5.9E-21 T 23-10-2018 IPR002881 Domain of unknown function DUF58 TAM4_575 c30da11f4c49b75c65bd175ac705afac 121 SUPERFAMILY SSF53146 1 109 2.49E-25 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_575 c30da11f4c49b75c65bd175ac705afac 121 Gene3D G3DSA:3.30.420.130 1 103 5.7E-25 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_575 c30da11f4c49b75c65bd175ac705afac 121 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 101 2.3E-17 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TAM4_252 32fb2555ffce649ce6434fd521d12176 426 Pfam PF03600 Citrate transporter 16 366 2.5E-53 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TAM4_252 32fb2555ffce649ce6434fd521d12176 426 PRINTS PR00758 Arsenical pump membrane protein signature 322 344 1.1E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TAM4_252 32fb2555ffce649ce6434fd521d12176 426 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 1.1E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TAM4_252 32fb2555ffce649ce6434fd521d12176 426 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.1E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TAM4_252 32fb2555ffce649ce6434fd521d12176 426 PRINTS PR00758 Arsenical pump membrane protein signature 221 246 1.1E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TAM4_252 32fb2555ffce649ce6434fd521d12176 426 PRINTS PR00758 Arsenical pump membrane protein signature 362 387 1.1E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TAM4_1153 8e28ac687c8f22c637b8c9e2766c1435 284 Pfam PF00892 EamA-like transporter family 3 136 1.0E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1153 8e28ac687c8f22c637b8c9e2766c1435 284 Pfam PF00892 EamA-like transporter family 148 274 1.4E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1153 8e28ac687c8f22c637b8c9e2766c1435 284 SUPERFAMILY SSF103481 38 137 1.5E-14 T 23-10-2018 TAM4_1153 8e28ac687c8f22c637b8c9e2766c1435 284 SUPERFAMILY SSF103481 184 280 5.75E-18 T 23-10-2018 TAM4_129 67afb1751a97ddda2e5cdde9e03d0a77 104 SUPERFAMILY SSF81301 9 90 5.36E-17 T 23-10-2018 TAM4_129 67afb1751a97ddda2e5cdde9e03d0a77 104 Pfam PF01909 Nucleotidyltransferase domain 9 60 2.4E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_129 67afb1751a97ddda2e5cdde9e03d0a77 104 Gene3D G3DSA:3.30.460.10 3 104 1.1E-17 T 23-10-2018 TAM4_210 465243d73592102c1360cf2485ddd540 107 Pfam PF05763 Protein of unknown function (DUF835) 8 103 1.4E-19 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1218 28892ed1143bc84eb391cf5090a2ae57 255 Gene3D G3DSA:3.60.15.10 1 255 5.0E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1218 28892ed1143bc84eb391cf5090a2ae57 255 Pfam PF12706 Beta-lactamase superfamily domain 46 223 5.8E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_1218 28892ed1143bc84eb391cf5090a2ae57 255 SUPERFAMILY SSF56281 1 255 1.17E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TAM4_1218 28892ed1143bc84eb391cf5090a2ae57 255 SMART SM00849 36 222 9.2E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TAM4_281 e00e4180f55a5d8080b34f4449097e96 173 Pfam PF01956 Integral membrane protein DUF106 17 171 2.4E-28 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TAM4_281 e00e4180f55a5d8080b34f4449097e96 173 SMART SM01415 21 172 1.2E-17 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TAM4_2434 079cdc1c533142e935facdc996ea7647 248 Gene3D G3DSA:3.40.50.300 5 247 1.2E-67 T 23-10-2018 TAM4_1186 89a793c363afb7865a229c8fcb689f4a 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 337 8.7E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_1186 89a793c363afb7865a229c8fcb689f4a 341 Gene3D G3DSA:1.10.3720.10 91 338 5.1E-6 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1608 71d7c7532e9ea8ea1897431d1dcac822 368 Gene3D G3DSA:1.20.1250.20 2 188 2.5E-40 T 23-10-2018 TAM4_1608 71d7c7532e9ea8ea1897431d1dcac822 368 SUPERFAMILY SSF103473 5 358 2.62E-66 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1608 71d7c7532e9ea8ea1897431d1dcac822 368 Pfam PF07690 Major Facilitator Superfamily 10 186 5.7E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1608 71d7c7532e9ea8ea1897431d1dcac822 368 Pfam PF07690 Major Facilitator Superfamily 198 355 2.1E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1608 71d7c7532e9ea8ea1897431d1dcac822 368 Gene3D G3DSA:1.20.1250.20 196 364 2.8E-24 T 23-10-2018 TAM4_2423 27fb359e5e01abfd65f505d1859c5957 164 Gene3D G3DSA:1.20.58.2050 1 164 1.7E-77 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 TAM4_2423 27fb359e5e01abfd65f505d1859c5957 164 Pfam PF05916 GINS complex protein 27 147 1.7E-6 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 TAM4_2161 7445c2fdde5a9e3431f13f6f4943c714 130 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 7 129 5.7E-65 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 TAM4_2195 9b0043603c045b582e6a52dd30d43816 133 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 8 128 1.8E-6 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 TAM4_1592 b3dce300a4fc06d6e1e3fa8f2e366eeb 416 Pfam PF04409 Protein of unknown function (DUF530) 5 257 4.8E-23 T 23-10-2018 IPR007503 Protein of unknown function DUF530 TAM4_1592 b3dce300a4fc06d6e1e3fa8f2e366eeb 416 PIRSF PIRSF018863 1 406 2.9E-182 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 TAM4_2077 32d9533ba7827a5ca52cdde8aae94538 232 Gene3D G3DSA:3.30.1490.20 39 116 7.1E-92 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TAM4_2077 32d9533ba7827a5ca52cdde8aae94538 232 Gene3D G3DSA:3.30.470.20 21 230 7.1E-92 T 23-10-2018 TAM4_2077 32d9533ba7827a5ca52cdde8aae94538 232 SUPERFAMILY SSF56059 23 232 5.13E-52 T 23-10-2018 TAM4_2077 32d9533ba7827a5ca52cdde8aae94538 232 Pfam PF13549 ATP-grasp domain 16 231 1.7E-84 T 23-10-2018 TAM4_293 19e2cfc8790ac7748fa5e1a40879aee9 306 PIRSF PIRSF004976 1 305 2.2E-97 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TAM4_293 19e2cfc8790ac7748fa5e1a40879aee9 306 SUPERFAMILY SSF52402 26 247 2.21E-51 T 23-10-2018 TAM4_293 19e2cfc8790ac7748fa5e1a40879aee9 306 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 194 293 5.1E-25 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TAM4_293 19e2cfc8790ac7748fa5e1a40879aee9 306 Pfam PF01171 PP-loop family 52 222 2.5E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TAM4_293 19e2cfc8790ac7748fa5e1a40879aee9 306 Gene3D G3DSA:3.40.50.620 3 305 2.6E-92 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_857 e1c9845e3d8ffec0af298df0eb94ccb0 387 Pfam PF04981 NMD3 family 4 274 2.8E-63 T 23-10-2018 IPR007064 Nmd3, N-terminal TAM4_857 e1c9845e3d8ffec0af298df0eb94ccb0 387 Gene3D G3DSA:2.40.50.140 330 382 1.1E-6 T 23-10-2018 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SUPERFAMILY SSF50998 2 262 2.51E-44 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 141 177 33.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 14 52 0.041 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 219 258 14.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 179 217 100.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 95 137 51.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00320 54 92 0.007 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00564 30 62 0.09 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00564 117 147 42.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00564 195 227 0.075 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00564 156 187 44.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 SMART SM00564 70 103 4.8E-5 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 Gene3D G3DSA:2.130.10.10 1 303 5.0E-40 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 Pfam PF13360 PQQ-like domain 6 150 2.2E-13 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TAM4_970 9ef1d8c10f55dc955c0610cff8daf47e 1135 Pfam PF13360 PQQ-like domain 162 300 1.3E-7 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TAM4_2129 a05175227c5633b2e0fd332c819024f0 223 Pfam PF04256 Protein of unknown function (DUF434) 2 56 2.3E-23 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TAM4_2129 a05175227c5633b2e0fd332c819024f0 223 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 53 1.0E-15 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TAM4_2132 76740a82b6fdf8b8a4073ead6c16d9eb 242 Gene3D G3DSA:1.10.3720.10 37 238 5.8E-12 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_2132 76740a82b6fdf8b8a4073ead6c16d9eb 242 SUPERFAMILY SSF161098 43 228 1.31E-13 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_310 cc67cbb5e7938bc95edde5865bcc617e 148 Pfam PF08905 Domain of unknown function (DUF1850) 41 120 1.7E-12 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 TAM4_1507 aea067d2d89d4c421f0698306596350c 119 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 11 110 26.056 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TAM4_1507 aea067d2d89d4c421f0698306596350c 119 PIRSF PIRSF004878 1 117 5.4E-42 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TAM4_1507 aea067d2d89d4c421f0698306596350c 119 Gene3D G3DSA:1.20.5.420 6 64 1.5E-21 T 23-10-2018 TAM4_1507 aea067d2d89d4c421f0698306596350c 119 Gene3D G3DSA:2.20.25.200 65 119 2.4E-25 T 23-10-2018 TAM4_1507 aea067d2d89d4c421f0698306596350c 119 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 22 101 2.2E-16 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TAM4_704 7876898676daa4649d04f5f2cd07eb98 209 Gene3D G3DSA:3.40.50.1000 1 199 5.5E-54 T 23-10-2018 IPR023214 HAD superfamily TAM4_704 7876898676daa4649d04f5f2cd07eb98 209 SUPERFAMILY SSF56784 1 206 2.0E-43 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_704 7876898676daa4649d04f5f2cd07eb98 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 173 1.1E-21 T 23-10-2018 TAM4_704 7876898676daa4649d04f5f2cd07eb98 209 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 174 8.8E-34 T 23-10-2018 TAM4_704 7876898676daa4649d04f5f2cd07eb98 209 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 3 184 1.1E-55 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal TAM4_1264 165fd37188d14a74fb0f91e84c7f62d6 403 Pfam PF01384 Phosphate transporter family 19 392 1.1E-110 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TAM4_2390 31382467fa259fd8b581375a1e01e96f 487 SUPERFAMILY SSF52402 109 188 4.19E-6 T 23-10-2018 TAM4_2390 31382467fa259fd8b581375a1e01e96f 487 Gene3D G3DSA:3.40.50.620 147 365 6.4E-8 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TAM4_2338 fdc75c70ab9b70bf9e51a476ce152b99 250 Gene3D G3DSA:3.40.50.300 8 244 2.9E-58 T 23-10-2018 TAM4_1542 bc35cc59fcb4445bc2b33f1ecc59c749 207 Pfam PF01694 Rhomboid family 56 191 7.6E-30 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TAM4_1542 bc35cc59fcb4445bc2b33f1ecc59c749 207 SUPERFAMILY SSF144091 11 194 1.11E-39 T 23-10-2018 TAM4_1542 bc35cc59fcb4445bc2b33f1ecc59c749 207 Gene3D G3DSA:1.20.1540.10 7 200 3.3E-39 T 23-10-2018 IPR035952 Rhomboid-like superfamily TAM4_1484 f3c49b6402f9b030cf77518d6b5178f2 571 SUPERFAMILY SSF63829 78 318 7.52E-8 T 23-10-2018 TAM4_1484 f3c49b6402f9b030cf77518d6b5178f2 571 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 553 571 7.6E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 SMART SM00116 102 149 4.8E-10 T 23-10-2018 IPR000644 CBS domain TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 SMART SM00116 25 71 2.4 T 23-10-2018 IPR000644 CBS domain TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 Gene3D G3DSA:3.10.580.10 4 150 8.0E-24 T 23-10-2018 TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 Pfam PF00571 CBS domain 95 148 6.7E-12 T 23-10-2018 IPR000644 CBS domain TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 Pfam PF00571 CBS domain 22 71 5.7E-7 T 23-10-2018 IPR000644 CBS domain TAM4_1315 fbf269fdf57568fbec56e43321e9d4d6 153 SUPERFAMILY SSF54631 9 148 8.12E-24 T 23-10-2018 TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 SUPERFAMILY SSF161093 226 393 8.5E-25 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 Pfam PF01769 Divalent cation transporter 265 389 4.9E-19 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 Pfam PF01769 Divalent cation transporter 61 184 3.0E-16 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 SUPERFAMILY SSF161093 18 192 3.66E-26 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 Gene3D G3DSA:1.10.357.20 224 396 2.1E-13 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TAM4_2037 a3d4df96463d0e179c9c16710a09553d 396 Gene3D G3DSA:1.10.357.20 20 192 1.5E-7 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TAM4_1168 a62da4aa08f6c04f308aeda6a7f02589 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 2.7E-71 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1168 a62da4aa08f6c04f308aeda6a7f02589 214 Pfam PF01813 ATP synthase subunit D 13 206 3.7E-62 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1168 a62da4aa08f6c04f308aeda6a7f02589 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.788 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_738 6d1e63087301eba477842032eae451c0 451 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 22 445 7.2E-90 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TAM4_738 6d1e63087301eba477842032eae451c0 451 Gene3D G3DSA:3.30.1110.20 30 202 1.9E-146 T 23-10-2018 TAM4_738 6d1e63087301eba477842032eae451c0 451 SUPERFAMILY SSF53613 2 450 2.84E-148 T 23-10-2018 IPR029056 Ribokinase-like TAM4_738 6d1e63087301eba477842032eae451c0 451 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 451 59.167 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 TAM4_738 6d1e63087301eba477842032eae451c0 451 Gene3D G3DSA:3.40.1190.20 23 445 1.9E-146 T 23-10-2018 IPR029056 Ribokinase-like TAM4_2011 02df5db119893ab31725afb1baf69ba0 808 Gene3D G3DSA:3.40.50.880 515 698 8.7E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_2011 02df5db119893ab31725afb1baf69ba0 808 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 65 680 2.3E-63 T 23-10-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain TAM4_2011 02df5db119893ab31725afb1baf69ba0 808 SUPERFAMILY SSF52317 530 681 1.1E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_1763 fd0f5ee6a875667cdefff61e6f44f8ca 127 Pfam PF02641 Uncharacterized ACR, COG1993 11 105 4.8E-39 T 23-10-2018 IPR003793 Domain of unknown function DUF190 TAM4_1763 fd0f5ee6a875667cdefff61e6f44f8ca 127 Gene3D G3DSA:3.30.70.120 1 127 2.4E-56 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TAM4_1763 fd0f5ee6a875667cdefff61e6f44f8ca 127 SUPERFAMILY SSF54913 8 107 1.06E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TAM4_1379 2cb1061973a6b914da71bef3cbf98976 283 Pfam PF05681 Fumarate hydratase (Fumerase) 3 269 2.0E-95 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TAM4_1379 2cb1061973a6b914da71bef3cbf98976 283 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 2 273 3.1E-119 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TAM4_233 09ec9be41e0d12151ab1e94f6bd1e36e 194 Gene3D G3DSA:3.40.920.10 1 194 1.0E-34 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_233 09ec9be41e0d12151ab1e94f6bd1e36e 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 188 3.6E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TAM4_233 09ec9be41e0d12151ab1e94f6bd1e36e 194 SUPERFAMILY SSF53323 2 193 7.59E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 Gene3D G3DSA:1.10.3720.10 19 315 2.3E-50 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 Gene3D G3DSA:1.10.3720.10 483 733 5.9E-42 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 543 728 3.0E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 304 1.5E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 SUPERFAMILY SSF161098 333 730 4.39E-40 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_2118 c9edd0d5884406f96dbfc1707a388d0f 738 SUPERFAMILY SSF161098 22 311 3.74E-42 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1692 25f8a1124973f62e5e9815bde5fb2b57 202 Pfam PF00881 Nitroreductase family 7 181 1.8E-37 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TAM4_1692 25f8a1124973f62e5e9815bde5fb2b57 202 SUPERFAMILY SSF55469 1 201 2.09E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TAM4_1692 25f8a1124973f62e5e9815bde5fb2b57 202 Gene3D G3DSA:3.40.109.10 1 200 5.4E-53 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TAM4_612 48f4dee1bdc85956f8e207db77e5b576 101 SUPERFAMILY SSF81301 4 100 7.95E-23 T 23-10-2018 TAM4_612 48f4dee1bdc85956f8e207db77e5b576 101 Pfam PF01909 Nucleotidyltransferase domain 10 90 1.1E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_612 48f4dee1bdc85956f8e207db77e5b576 101 Gene3D G3DSA:3.30.460.10 2 98 5.7E-22 T 23-10-2018 TAM4_456 be127c62787438a9567f9b0bfa16255b 210 SUPERFAMILY SSF53335 3 190 6.72E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TAM4_456 be127c62787438a9567f9b0bfa16255b 210 Gene3D G3DSA:3.40.50.150 1 205 2.1E-68 T 23-10-2018 TAM4_456 be127c62787438a9567f9b0bfa16255b 210 Pfam PF05175 Methyltransferase small domain 45 126 2.3E-16 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TAM4_456 be127c62787438a9567f9b0bfa16255b 210 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TAM4_715 698c3da7be1be8f9f88230bd72b0fe3c 86 Pfam PF03683 Uncharacterised protein family (UPF0175) 9 81 1.4E-27 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 5.7E-46 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 28.162 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 SUPERFAMILY SSF82704 5 90 1.7E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 7.0E-40 T 23-10-2018 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 Gene3D G3DSA:3.30.110.20 2 90 7.1E-39 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 PIRSF PIRSF028732 1 91 1.8E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TAM4_1802 36cc600d57fe44d50ea57cd36346cba7 91 Pfam PF01918 Alba 6 66 1.6E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 TAM4_1026 670e8fe833a6e81743497e615d05b628 780 Gene3D G3DSA:3.40.50.12610 482 607 2.2E-11 T 23-10-2018 TAM4_1026 670e8fe833a6e81743497e615d05b628 780 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 55 271 1.0E-11 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 TAM4_1668 8c25fb746620df0c3bfcf7e92d3f69e4 154 SUPERFAMILY SSF88723 5 146 4.77E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1668 8c25fb746620df0c3bfcf7e92d3f69e4 154 Pfam PF01850 PIN domain 7 140 1.2E-11 T 23-10-2018 IPR002716 PIN domain TAM4_1668 8c25fb746620df0c3bfcf7e92d3f69e4 154 Gene3D G3DSA:3.40.50.1010 6 142 6.8E-10 T 23-10-2018 TAM4_1719 eef5f495ba2eb0c7f93d31ac01a89c98 255 Pfam PF12679 ABC-2 family transporter protein 75 249 1.1E-10 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TAM4_1477 f20f1a653482f7916b27c496e392e213 326 Gene3D G3DSA:3.40.50.1980 25 185 4.8E-29 T 23-10-2018 TAM4_1477 f20f1a653482f7916b27c496e392e213 326 SUPERFAMILY SSF53807 22 288 6.38E-44 T 23-10-2018 TAM4_1477 f20f1a653482f7916b27c496e392e213 326 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 281 4.0E-33 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TAM4_1313 7609316b2eb08b0cb20d99dea593ef68 127 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 92 1.0E-29 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TAM4_1313 7609316b2eb08b0cb20d99dea593ef68 127 Pfam PF04322 Protein of unknown function (DUF473) 1 111 1.9E-31 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TAM4_453 6e59b1d8056a79649904db31440c01cd 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 380 2.9E-124 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 TAM4_453 6e59b1d8056a79649904db31440c01cd 421 Gene3D G3DSA:3.20.20.140 3 233 4.5E-13 T 23-10-2018 TAM4_453 6e59b1d8056a79649904db31440c01cd 421 SUPERFAMILY SSF89550 5 227 4.71E-13 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TAM4_28 f29a4340142c047464992fd7c8deeeb9 547 SUPERFAMILY SSF52096 27 282 2.2E-78 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TAM4_28 f29a4340142c047464992fd7c8deeeb9 547 Pfam PF01039 Carboxyl transferase domain 53 545 8.9E-202 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TAM4_28 f29a4340142c047464992fd7c8deeeb9 547 SUPERFAMILY SSF52096 269 547 8.66E-94 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TAM4_28 f29a4340142c047464992fd7c8deeeb9 547 Gene3D G3DSA:3.90.226.10 287 547 1.0E-96 T 23-10-2018 TAM4_28 f29a4340142c047464992fd7c8deeeb9 547 Gene3D G3DSA:3.90.226.10 24 285 6.4E-97 T 23-10-2018 TAM4_702 02dc427c7b954578b59ef87f338e4463 69 SUPERFAMILY SSF141694 1 60 1.78E-15 T 23-10-2018 TAM4_702 02dc427c7b954578b59ef87f338e4463 69 Pfam PF01954 Protein of unknown function DUF104 1 55 3.0E-18 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_702 02dc427c7b954578b59ef87f338e4463 69 Gene3D G3DSA:4.10.1150.10 1 65 8.6E-16 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_1585 d0d6ccae3a916c5a26464a2f761bf04a 215 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 5.4E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TAM4_1585 d0d6ccae3a916c5a26464a2f761bf04a 215 Pfam PF01917 Archaebacterial flagellin 8 201 7.4E-49 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_110 509208dd4c84657d08ef2c2bbe7ef91c 608 Pfam PF00149 Calcineurin-like phosphoesterase 389 554 3.1E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_110 509208dd4c84657d08ef2c2bbe7ef91c 608 Gene3D G3DSA:3.60.21.10 380 602 1.3E-14 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_110 509208dd4c84657d08ef2c2bbe7ef91c 608 SUPERFAMILY SSF56300 389 607 1.86E-30 T 23-10-2018 TAM4_1805 20085ff16be73ad9d4fcd62c3c357e11 443 Gene3D G3DSA:1.20.1530.20 3 412 1.6E-66 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_1805 20085ff16be73ad9d4fcd62c3c357e11 443 Pfam PF00999 Sodium/hydrogen exchanger family 9 403 1.0E-45 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_2155 f6c65fe587574bbb899e02e7decf2d06 128 SMART SM00530 20 73 6.3E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TAM4_2155 f6c65fe587574bbb899e02e7decf2d06 128 Pfam PF01022 Bacterial regulatory protein, arsR family 17 51 1.5E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TAM4_2155 f6c65fe587574bbb899e02e7decf2d06 128 SUPERFAMILY SSF47413 14 53 1.15E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TAM4_2155 f6c65fe587574bbb899e02e7decf2d06 128 Gene3D G3DSA:1.10.260.40 9 62 2.0E-7 T 23-10-2018 TAM4_1527 da7973af0207416b7872c9b8f6b8de7e 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 4.8E-243 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TAM4_1527 da7973af0207416b7872c9b8f6b8de7e 562 SUPERFAMILY SSF51703 9 556 9.42E-233 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TAM4_1527 da7973af0207416b7872c9b8f6b8de7e 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 2.3E-294 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TAM4_1527 da7973af0207416b7872c9b8f6b8de7e 562 Gene3D G3DSA:3.20.20.240 1 562 7.1E-271 T 23-10-2018 TAM4_1166 42139614ebeb1d0e2f9f7320bb249b3f 396 SUPERFAMILY SSF52540 56 305 7.2E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1166 42139614ebeb1d0e2f9f7320bb249b3f 396 Gene3D G3DSA:3.40.50.300 46 235 1.4E-9 T 23-10-2018 TAM4_1715 e204fa72948c95f59faa1be232b1c548 439 SUPERFAMILY SSF52540 34 194 4.32E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1715 e204fa72948c95f59faa1be232b1c548 439 Pfam PF13173 AAA domain 35 161 1.6E-34 T 23-10-2018 TAM4_1715 e204fa72948c95f59faa1be232b1c548 439 Pfam PF13635 Domain of unknown function (DUF4143) 218 367 1.2E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1581 965a438066f5d78f0c33b550b75eece5 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 27 215 1.2E-11 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TAM4_1581 965a438066f5d78f0c33b550b75eece5 237 PIRSF PIRSF015736 1 237 3.6E-87 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TAM4_1581 965a438066f5d78f0c33b550b75eece5 237 Gene3D G3DSA:3.40.50.12500 6 237 1.8E-86 T 23-10-2018 TAM4_1950 565f76aca928754716e7520b86c09ada 187 SUPERFAMILY SSF48371 33 147 2.55E-13 T 23-10-2018 IPR016024 Armadillo-type fold TAM4_1950 565f76aca928754716e7520b86c09ada 187 Gene3D G3DSA:1.25.10.10 14 130 7.5E-10 T 23-10-2018 IPR011989 Armadillo-like helical TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 Gene3D G3DSA:1.20.1250.20 1 375 6.9E-49 T 23-10-2018 TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 SUPERFAMILY SSF103473 2 378 6.93E-56 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 Pfam PF07690 Major Facilitator Superfamily 9 343 1.5E-43 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 PRINTS PR01035 Tetracycline resistance protein signature 13 29 3.9E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.9E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1629 361db61a206abcb84bb89e1a48bb635f 386 PRINTS PR01035 Tetracycline resistance protein signature 293 313 3.9E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TAM4_1841 82096e4ba931b9f6bd81d732b2bd34d9 216 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 27 1.0E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TAM4_1841 82096e4ba931b9f6bd81d732b2bd34d9 216 Pfam PF01917 Archaebacterial flagellin 6 202 1.2E-47 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_2316 83953f957a13f7219b58798162af4459 160 Pfam PF03773 Predicted permease 28 159 8.1E-12 T 23-10-2018 IPR005524 Predicted permease DUF318 TAM4_1328 cc6a9aa1e28a7253556c3c8f3eb97060 102 SUPERFAMILY SSF159468 3 100 3.01E-19 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1328 cc6a9aa1e28a7253556c3c8f3eb97060 102 Gene3D G3DSA:3.40.50.10580 1 102 6.1E-33 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1328 cc6a9aa1e28a7253556c3c8f3eb97060 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.043 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TAM4_1328 cc6a9aa1e28a7253556c3c8f3eb97060 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 1.1E-18 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TAM4_1409 69e9061c6973675fb6d8f7b57c2e38dd 411 SUPERFAMILY SSF161098 197 396 2.62E-16 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1409 69e9061c6973675fb6d8f7b57c2e38dd 411 Gene3D G3DSA:1.10.3720.10 195 405 6.9E-16 T 23-10-2018 IPR035906 MetI-like superfamily TAM4_1409 69e9061c6973675fb6d8f7b57c2e38dd 411 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 222 398 9.0E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TAM4_2164 035fe398d882db5215655550a1bd309b 187 Pfam PF00881 Nitroreductase family 8 165 2.0E-26 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TAM4_2164 035fe398d882db5215655550a1bd309b 187 Gene3D G3DSA:3.40.109.10 2 185 3.0E-44 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TAM4_2164 035fe398d882db5215655550a1bd309b 187 SUPERFAMILY SSF55469 1 187 1.83E-43 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TAM4_2416 4c2b8acfe13c7afd41e3c5d7a9728ef7 475 SUPERFAMILY SSF50998 22 191 2.79E-10 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TAM4_2416 4c2b8acfe13c7afd41e3c5d7a9728ef7 475 Gene3D G3DSA:2.130.10.10 14 255 1.6E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TAM4_2416 4c2b8acfe13c7afd41e3c5d7a9728ef7 475 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 357 6.8E-143 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TAM4_776 e6a38c3235a86d262dbf5603b4fc296b 141 SUPERFAMILY SSF111038 4 131 3.79E-40 T 23-10-2018 IPR035917 YjbQ-like superfamily TAM4_776 e6a38c3235a86d262dbf5603b4fc296b 141 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 1.7E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_776 e6a38c3235a86d262dbf5603b4fc296b 141 Gene3D G3DSA:2.60.120.460 1 132 7.3E-48 T 23-10-2018 IPR035917 YjbQ-like superfamily TAM4_776 e6a38c3235a86d262dbf5603b4fc296b 141 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 6 131 7.5E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_776 e6a38c3235a86d262dbf5603b4fc296b 141 PIRSF PIRSF004681 1 133 4.8E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TAM4_1053 4b940cb2425952c9f6c9caaedf131faf 252 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 109 231 9.5E-21 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1152 1171 3.2E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 SUPERFAMILY SSF49899 418 596 7.45E-21 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 Gene3D G3DSA:2.60.120.200 840 942 1.6E-21 T 23-10-2018 TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 Gene3D G3DSA:2.60.120.200 417 531 1.2E-23 T 23-10-2018 TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 Gene3D G3DSA:2.60.120.200 943 1021 4.3E-8 T 23-10-2018 TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 Pfam PF08308 PEGA domain 1032 1098 1.2E-14 T 23-10-2018 IPR013229 PEGA TAM4_1876 ab46dec69ad7f1d46c8fa9e14fd8fe43 1173 SUPERFAMILY SSF49899 844 1019 5.74E-20 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TAM4_2186 cccfbb273a6475a497f2ed5988f49328 331 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 320 6.6E-79 T 23-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TAM4_2186 cccfbb273a6475a497f2ed5988f49328 331 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 203 3.8E-43 T 23-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TAM4_1502 f682c90933dc65a621673f449fdc84ce 736 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 716 735 4.0E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_1502 f682c90933dc65a621673f449fdc84ce 736 SUPERFAMILY SSF56300 131 424 4.8E-28 T 23-10-2018 TAM4_1502 f682c90933dc65a621673f449fdc84ce 736 Gene3D G3DSA:3.60.21.10 182 436 1.3E-16 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_1502 f682c90933dc65a621673f449fdc84ce 736 Pfam PF00149 Calcineurin-like phosphoesterase 131 367 3.1E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TAM4_714 fc20beb77f3467a3fb3c545e7f0d1570 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 1.1E-9 T 23-10-2018 IPR001451 Hexapeptide repeat TAM4_714 fc20beb77f3467a3fb3c545e7f0d1570 174 Gene3D G3DSA:2.160.10.10 1 172 2.2E-64 T 23-10-2018 TAM4_714 fc20beb77f3467a3fb3c545e7f0d1570 174 SUPERFAMILY SSF51161 4 169 6.38E-52 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TAM4_322 1432e808fafd45da10dc5bba15000ebe 79 Gene3D G3DSA:3.30.920.30 6 74 1.0E-15 T 23-10-2018 IPR038570 HicA superfamily TAM4_322 1432e808fafd45da10dc5bba15000ebe 79 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 67 2.4E-14 T 23-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TAM4_322 1432e808fafd45da10dc5bba15000ebe 79 SUPERFAMILY SSF54786 4 74 1.37E-13 T 23-10-2018 TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.2E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.2E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.2E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.2E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.2E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 5.7E-50 T 23-10-2018 TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 SUPERFAMILY SSF51735 8 258 2.0E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_2165 d8c64f50663746d9b19f21e6da434f84 263 Gene3D G3DSA:3.40.50.720 3 258 1.8E-64 T 23-10-2018 TAM4_115 07ecaa5dae469488b6e2332f71af4f7a 152 Pfam PF04021 Class III signal peptide 2 25 2.8E-6 T 23-10-2018 IPR007166 Class III signal peptide motif TAM4_61 3549331032ef7e97dddecb36df01ef84 334 Gene3D G3DSA:1.10.3470.10 2 331 2.3E-93 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_61 3549331032ef7e97dddecb36df01ef84 334 Pfam PF01032 FecCD transport family 13 326 6.4E-86 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TAM4_61 3549331032ef7e97dddecb36df01ef84 334 SUPERFAMILY SSF81345 3 326 6.02E-77 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TAM4_884 ca1a3648fe990d9f1e53b563d1dadfb7 246 Gene3D G3DSA:3.30.390.100 29 100 6.5E-23 T 23-10-2018 TAM4_884 ca1a3648fe990d9f1e53b563d1dadfb7 246 Pfam PF13938 Putative heavy-metal chelation 17 89 7.7E-11 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 TAM4_884 ca1a3648fe990d9f1e53b563d1dadfb7 246 Pfam PF04016 Putative heavy-metal chelation 103 242 2.4E-34 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain TAM4_884 ca1a3648fe990d9f1e53b563d1dadfb7 246 SUPERFAMILY SSF159713 12 242 1.96E-58 T 23-10-2018 TAM4_884 ca1a3648fe990d9f1e53b563d1dadfb7 246 Gene3D G3DSA:3.40.50.11590 101 214 6.5E-23 T 23-10-2018 TAM4_1384 e4cc6c2315735bac531afc17e78c2680 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 2.3E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_1384 e4cc6c2315735bac531afc17e78c2680 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 1.9E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TAM4_2008 c255b4c9c118cc80044d0d97b6a10b77 96 SUPERFAMILY SSF46579 5 95 4.18E-8 T 23-10-2018 TAM4_2008 c255b4c9c118cc80044d0d97b6a10b77 96 Pfam PF01920 Prefoldin subunit 6 96 1.7E-7 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TAM4_2008 c255b4c9c118cc80044d0d97b6a10b77 96 Gene3D G3DSA:1.10.287.370 1 96 3.7E-40 T 23-10-2018 IPR009053 Prefoldin TAM4_1047 18f547720f5d46cafbdde64f3f839e92 144 Gene3D G3DSA:1.20.1260.10 1 144 1.3E-13 T 23-10-2018 IPR012347 Ferritin-like TAM4_1047 18f547720f5d46cafbdde64f3f839e92 144 SUPERFAMILY SSF47240 3 143 1.94E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1047 18f547720f5d46cafbdde64f3f839e92 144 Pfam PF02915 Rubrerythrin 92 143 1.7E-5 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TAM4_1064 c24c92bccef7472b02bcaf4885b2e880 588 SUPERFAMILY SSF46785 389 454 4.23E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1064 c24c92bccef7472b02bcaf4885b2e880 588 Gene3D G3DSA:1.10.10.10 380 441 4.7E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1064 c24c92bccef7472b02bcaf4885b2e880 588 Pfam PF13412 Winged helix-turn-helix DNA-binding 391 437 6.6E-6 T 23-10-2018 TAM4_2066 07b5d564477d8ea712d8935cff8eb522 150 SUPERFAMILY SSF56784 13 131 9.43E-12 T 23-10-2018 IPR036412 HAD-like superfamily TAM4_2066 07b5d564477d8ea712d8935cff8eb522 150 Gene3D G3DSA:3.40.50.1000 10 143 1.2E-8 T 23-10-2018 IPR023214 HAD superfamily TAM4_2007 729e3abbfd66f6f9152c1399b94edd7f 66 SUPERFAMILY SSF141694 1 39 3.14E-11 T 23-10-2018 TAM4_2007 729e3abbfd66f6f9152c1399b94edd7f 66 Gene3D G3DSA:4.10.1150.10 1 64 9.0E-10 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_2007 729e3abbfd66f6f9152c1399b94edd7f 66 Pfam PF01954 Protein of unknown function DUF104 2 56 1.1E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_2365 c31d57410759b6c78db6ae2addd23d3c 114 Pfam PF11848 Domain of unknown function (DUF3368) 64 109 6.2E-18 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_1671 e9da79ead022a81821f867730da49ee4 429 SUPERFAMILY SSF161070 13 408 1.31E-9 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TAM4_981 e2801654d17f98266a70aeeddd949b1a 571 Pfam PF02554 Carbon starvation protein CstA 1 352 1.1E-110 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TAM4_981 e2801654d17f98266a70aeeddd949b1a 571 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 403 520 4.0E-30 T 23-10-2018 IPR025299 CstA, C-terminal domain TAM4_387 5a42d7316b69fc9d87104cfebbf643dd 440 Pfam PF07282 Putative transposase DNA-binding domain 320 388 3.6E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_387 5a42d7316b69fc9d87104cfebbf643dd 440 Pfam PF01385 Probable transposase 180 299 4.5E-34 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TAM4_387 5a42d7316b69fc9d87104cfebbf643dd 440 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 269 346 3.4E-9 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_1732 694b011604941f36c85484250374d55d 431 Gene3D G3DSA:1.10.575.10 23 179 6.1E-12 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TAM4_1732 694b011604941f36c85484250374d55d 431 SMART SM00770 1 256 2.1E-65 T 23-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 TAM4_1732 694b011604941f36c85484250374d55d 431 SUPERFAMILY SSF48537 30 265 1.21E-37 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TAM4_1732 694b011604941f36c85484250374d55d 431 Pfam PF00882 Zinc dependent phospholipase C 37 186 1.2E-6 T 23-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 TAM4_1359 c05d99d57362de783d35f101b5fadde2 167 Gene3D G3DSA:3.10.450.220 1 93 2.3E-44 T 23-10-2018 TAM4_1359 c05d99d57362de783d35f101b5fadde2 167 Pfam PF03657 Uncharacterised protein family (UPF0113) 6 165 1.5E-10 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 TAM4_1359 c05d99d57362de783d35f101b5fadde2 167 Gene3D G3DSA:2.30.130.10 94 165 1.3E-19 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TAM4_844 349258c6185dc02e2643a0e095a349d4 136 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 114 1.3E-16 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TAM4_844 349258c6185dc02e2643a0e095a349d4 136 SUPERFAMILY SSF53146 3 117 2.75E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_844 349258c6185dc02e2643a0e095a349d4 136 Gene3D G3DSA:3.30.420.130 2 126 8.1E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_1143 a9cc37e91f4244a9be2000deeaf3c612 188 SUPERFAMILY SSF143243 21 173 3.66E-28 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1143 a9cc37e91f4244a9be2000deeaf3c612 188 Gene3D G3DSA:3.30.460.80 20 147 1.6E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1143 a9cc37e91f4244a9be2000deeaf3c612 188 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 103 164 8.0E-26 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1143 a9cc37e91f4244a9be2000deeaf3c612 188 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 49 164 4.8E-19 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1402 0ab53422f77e04e80f3c9046f9df8d5b 162 SUPERFAMILY SSF103165 2 160 3.53E-60 T 23-10-2018 IPR036902 Ta1353-like superfamily TAM4_1402 0ab53422f77e04e80f3c9046f9df8d5b 162 Gene3D G3DSA:3.40.1520.10 1 162 1.1E-72 T 23-10-2018 IPR036902 Ta1353-like superfamily TAM4_1402 0ab53422f77e04e80f3c9046f9df8d5b 162 Pfam PF04008 Adenosine specific kinase 7 159 3.1E-62 T 23-10-2018 IPR007153 Adenosine specific kinase TAM4_2189 3044b44815482e71d995ef156fd57542 119 Pfam PF01883 Iron-sulfur cluster assembly protein 16 54 8.1E-6 T 23-10-2018 IPR002744 MIP18 family-like TAM4_2189 3044b44815482e71d995ef156fd57542 119 SUPERFAMILY SSF117916 16 58 1.24E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TAM4_2189 3044b44815482e71d995ef156fd57542 119 Gene3D G3DSA:3.30.300.130 12 94 5.6E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TAM4_652 4e92f17d1df241c41c3fe86a9ed532fb 169 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 1 162 1.5E-50 T 23-10-2018 IPR005268 Conserved hypothetical protein CHP00725 TAM4_652 4e92f17d1df241c41c3fe86a9ed532fb 169 Gene3D G3DSA:3.40.50.450 1 165 2.5E-34 T 23-10-2018 TAM4_652 4e92f17d1df241c41c3fe86a9ed532fb 169 SUPERFAMILY SSF102405 1 162 7.33E-31 T 23-10-2018 TAM4_209 d8f67e57db53ba6d62b139ed33dd7ddf 123 Gene3D G3DSA:3.40.50.1010 2 122 1.6E-10 T 23-10-2018 TAM4_209 d8f67e57db53ba6d62b139ed33dd7ddf 123 Pfam PF01850 PIN domain 2 111 3.0E-13 T 23-10-2018 IPR002716 PIN domain TAM4_209 d8f67e57db53ba6d62b139ed33dd7ddf 123 SUPERFAMILY SSF88723 1 116 5.33E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_915 d59d6f7c37a6c6f75ba1bcc70c6d6ea6 623 SUPERFAMILY SSF69322 37 343 2.75E-6 T 23-10-2018 TAM4_915 d59d6f7c37a6c6f75ba1bcc70c6d6ea6 623 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 599 616 1.5E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_915 d59d6f7c37a6c6f75ba1bcc70c6d6ea6 623 Pfam PF08308 PEGA domain 484 550 7.8E-16 T 23-10-2018 IPR013229 PEGA TAM4_915 d59d6f7c37a6c6f75ba1bcc70c6d6ea6 623 Pfam PF08308 PEGA domain 440 480 5.8E-5 T 23-10-2018 IPR013229 PEGA TAM4_2109 5ffd94bd16a931437b9dd0f4a8a1a008 237 Pfam PF01963 TraB family 9 220 3.8E-13 T 23-10-2018 IPR002816 Pheromone shutdown, TraB TAM4_2197 23ad453e5c9b53737a75279ac4162cbc 382 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 243 4.0E-16 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TAM4_2197 23ad453e5c9b53737a75279ac4162cbc 382 Gene3D G3DSA:3.50.50.100 1 381 3.8E-68 T 23-10-2018 TAM4_2197 23ad453e5c9b53737a75279ac4162cbc 382 SUPERFAMILY SSF51905 2 150 3.89E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_2197 23ad453e5c9b53737a75279ac4162cbc 382 SUPERFAMILY SSF51905 119 247 6.49E-21 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TAM4_1483 f964accb8b281dc170bbf1b02aa4a04d 165 Pfam PF00583 Acetyltransferase (GNAT) family 60 154 1.3E-10 T 23-10-2018 IPR000182 GNAT domain TAM4_1483 f964accb8b281dc170bbf1b02aa4a04d 165 Gene3D G3DSA:3.40.630.30 14 154 1.2E-25 T 23-10-2018 TAM4_1483 f964accb8b281dc170bbf1b02aa4a04d 165 SUPERFAMILY SSF55729 28 158 4.12E-18 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 Pfam PF00571 CBS domain 72 124 6.7E-16 T 23-10-2018 IPR000644 CBS domain TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 Pfam PF00571 CBS domain 10 62 3.1E-11 T 23-10-2018 IPR000644 CBS domain TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 SUPERFAMILY SSF54631 9 128 5.94E-34 T 23-10-2018 TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 SMART SM00116 14 62 8.5E-9 T 23-10-2018 IPR000644 CBS domain TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 SMART SM00116 79 126 2.7E-9 T 23-10-2018 IPR000644 CBS domain TAM4_994 88e8288bb7a8c8f4f40ffc2d6057f70f 136 Gene3D G3DSA:3.10.580.10 1 136 2.6E-45 T 23-10-2018 TAM4_537 381de4fee5493b13c802563a51e428c6 267 Gene3D G3DSA:3.40.50.720 2 265 6.4E-49 T 23-10-2018 TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TAM4_537 381de4fee5493b13c802563a51e428c6 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 261 6.8E-31 T 23-10-2018 TAM4_537 381de4fee5493b13c802563a51e428c6 267 SUPERFAMILY SSF51735 9 262 8.92E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_1246 1fd38b02d7d9d757dbea871979321024 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 1.5E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TAM4_1246 1fd38b02d7d9d757dbea871979321024 175 SUPERFAMILY SSF52540 4 175 2.28E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1246 1fd38b02d7d9d757dbea871979321024 175 PIRSF PIRSF015617 1 175 5.4E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TAM4_1246 1fd38b02d7d9d757dbea871979321024 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 1.4E-70 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TAM4_1246 1fd38b02d7d9d757dbea871979321024 175 Gene3D G3DSA:3.40.50.300 1 175 3.8E-67 T 23-10-2018 TAM4_1440 fd536eee8f94b9fd7006f9de343e7ddf 134 SUPERFAMILY SSF81301 10 95 3.27E-12 T 23-10-2018 TAM4_1440 fd536eee8f94b9fd7006f9de343e7ddf 134 Pfam PF01909 Nucleotidyltransferase domain 14 83 5.7E-5 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1440 fd536eee8f94b9fd7006f9de343e7ddf 134 Gene3D G3DSA:3.30.460.10 5 93 4.2E-9 T 23-10-2018 TAM4_27 4148e4cd684c689a962cc7f9e21a05d1 258 SUPERFAMILY SSF55307 156 244 1.17E-11 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TAM4_27 4148e4cd684c689a962cc7f9e21a05d1 258 Gene3D G3DSA:3.40.50.1440 112 246 5.9E-11 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TAM4_1933 4225cb52ed1d43caa540d68f32bf1e91 176 Pfam PF00583 Acetyltransferase (GNAT) family 33 160 8.7E-14 T 23-10-2018 IPR000182 GNAT domain TAM4_1933 4225cb52ed1d43caa540d68f32bf1e91 176 Gene3D G3DSA:3.40.630.30 2 144 1.8E-54 T 23-10-2018 TAM4_1933 4225cb52ed1d43caa540d68f32bf1e91 176 SUPERFAMILY SSF55729 14 166 2.19E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TAM4_1933 4225cb52ed1d43caa540d68f32bf1e91 176 Gene3D G3DSA:3.30.1990.20 145 176 1.5E-8 T 23-10-2018 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 Pfam PF01368 DHH family 165 315 6.1E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 Pfam PF02272 DHHA1 domain 355 474 1.4E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 SUPERFAMILY SSF64182 162 453 4.06E-56 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 Gene3D G3DSA:3.90.1640.10 162 348 2.1E-26 T 23-10-2018 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 Gene3D G3DSA:3.40.50.720 1 144 2.4E-21 T 23-10-2018 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 Pfam PF02254 TrkA-N domain 3 107 6.7E-20 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TAM4_607 6fe0ed16c0b98d921999f8f15a5dfc4b 488 SUPERFAMILY SSF51735 1 138 2.37E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TAM4_486 4cbd4462326f8044a52a769b9b50e697 112 SUPERFAMILY SSF88723 4 104 1.99E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_486 4cbd4462326f8044a52a769b9b50e697 112 Pfam PF01850 PIN domain 4 104 1.2E-11 T 23-10-2018 IPR002716 PIN domain TAM4_2468 f155e7d6c3dbd0fbf2fad2176e1b373a 95 SUPERFAMILY SSF88723 3 82 9.25E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_2468 f155e7d6c3dbd0fbf2fad2176e1b373a 95 Gene3D G3DSA:3.40.50.1010 2 81 5.0E-7 T 23-10-2018 TAM4_2468 f155e7d6c3dbd0fbf2fad2176e1b373a 95 Pfam PF01850 PIN domain 14 75 2.2E-8 T 23-10-2018 IPR002716 PIN domain TAM4_201 2fa8f7b11ac3cfa25907e2b26be9c190 168 Pfam PF11848 Domain of unknown function (DUF3368) 113 158 1.9E-18 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_891 1bf1c053db3ce9c5c1f17166fcf5c9c3 264 Pfam PF13230 Glutamine amidotransferases class-II 31 122 3.5E-7 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 TAM4_891 1bf1c053db3ce9c5c1f17166fcf5c9c3 264 SUPERFAMILY SSF56235 40 249 1.98E-16 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_891 1bf1c053db3ce9c5c1f17166fcf5c9c3 264 Gene3D G3DSA:3.60.20.10 20 251 3.7E-14 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TAM4_1773 328546fb323ee31e2d56a8c001a6ec03 329 Pfam PF01594 AI-2E family transporter 10 323 4.7E-38 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TAM4_1515 aaf79608bc42e4af282cec97a1e38fe0 466 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 423 22.414 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 TAM4_1515 aaf79608bc42e4af282cec97a1e38fe0 466 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 236 8.1E-16 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TAM4_1515 aaf79608bc42e4af282cec97a1e38fe0 466 Gene3D G3DSA:3.30.110.80 233 332 8.1E-92 T 23-10-2018 TAM4_1515 aaf79608bc42e4af282cec97a1e38fe0 466 Gene3D G3DSA:3.60.21.10 1 278 8.1E-92 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TAM4_1515 aaf79608bc42e4af282cec97a1e38fe0 466 SUPERFAMILY SSF56300 1 315 3.8E-52 T 23-10-2018 TAM4_1670 4c658e62616311ab4792acf1eb75938a 70 Gene3D G3DSA:1.10.10.10 2 65 4.0E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1670 4c658e62616311ab4792acf1eb75938a 70 SUPERFAMILY SSF46785 4 52 2.26E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_799 ffe2ee25288ab801bfdc0a8496a47d49 263 SUPERFAMILY SSF55961 1 131 3.72E-6 T 23-10-2018 TAM4_1103 1ae6f771626b693ec5652930c79a2eb7 297 Pfam PF07690 Major Facilitator Superfamily 10 288 4.1E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1103 1ae6f771626b693ec5652930c79a2eb7 297 SUPERFAMILY SSF103473 10 279 2.75E-24 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1103 1ae6f771626b693ec5652930c79a2eb7 297 Gene3D G3DSA:1.20.1250.20 9 296 3.0E-23 T 23-10-2018 TAM4_743 2e0acb9c58335812c1348484a911337a 197 Pfam PF01955 Adenosylcobinamide amidohydrolase 8 181 1.9E-46 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ TAM4_937 42d4690e793cec5c0b944b6a2f41811c 236 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 5 236 37.535 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TAM4_937 42d4690e793cec5c0b944b6a2f41811c 236 Pfam PF03749 Sugar fermentation stimulation protein 16 219 2.7E-46 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TAM4_937 42d4690e793cec5c0b944b6a2f41811c 236 Gene3D G3DSA:2.40.50.580 3 80 2.7E-25 T 23-10-2018 TAM4_937 42d4690e793cec5c0b944b6a2f41811c 236 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 9 234 8.1E-51 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TAM4_937 42d4690e793cec5c0b944b6a2f41811c 236 Gene3D G3DSA:3.40.1350.60 81 236 1.6E-38 T 23-10-2018 TAM4_418 5895ecd890cc7ec8c60b3f6e2d229597 146 Pfam PF04024 PspC domain 6 64 1.2E-19 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TAM4_640 a399b81b7ed064ba113bd6e608b6eb17 221 Gene3D G3DSA:1.10.1760.20 1 210 6.7E-69 T 23-10-2018 TAM4_640 a399b81b7ed064ba113bd6e608b6eb17 221 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 210 8.3E-60 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 TAM4_740 09320861ac9ab4949335a16557cb644a 184 Pfam PF03729 Short repeat of unknown function (DUF308) 73 142 7.2E-10 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane TAM4_740 09320861ac9ab4949335a16557cb644a 184 Pfam PF03729 Short repeat of unknown function (DUF308) 16 86 1.7E-11 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane TAM4_353 7dff3974a2de4bd86d2975a3d229c204 154 Pfam PF01850 PIN domain 5 136 1.9E-21 T 23-10-2018 IPR002716 PIN domain TAM4_353 7dff3974a2de4bd86d2975a3d229c204 154 SUPERFAMILY SSF88723 1 136 4.49E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_353 7dff3974a2de4bd86d2975a3d229c204 154 SMART SM00670 2 133 3.1E-12 T 23-10-2018 IPR002716 PIN domain TAM4_353 7dff3974a2de4bd86d2975a3d229c204 154 Gene3D G3DSA:3.40.50.1010 4 144 6.6E-9 T 23-10-2018 TAM4_889 937ce9305022176df3a26cce0f5c6eeb 289 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 289 42.666 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 TAM4_889 937ce9305022176df3a26cce0f5c6eeb 289 Pfam PF03477 ATP cone domain 5 86 1.3E-8 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TAM4_889 937ce9305022176df3a26cce0f5c6eeb 289 SUPERFAMILY SSF52540 92 259 1.33E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_889 937ce9305022176df3a26cce0f5c6eeb 289 Gene3D G3DSA:3.40.50.300 92 280 9.6E-9 T 23-10-2018 TAM4_1056 9585261283409d39bb8db262b7a62e4e 63 Pfam PF10133 Predicted RNA-binding protein 1 61 7.0E-14 T 23-10-2018 IPR019300 RNA-binding protein, predicted TAM4_1736 daec6ebe88735c2650c9896d36326eca 272 Pfam PF01889 Membrane protein of unknown function DUF63 3 270 4.2E-88 T 23-10-2018 IPR002749 Protein of unknown function DUF63 TAM4_302 de154eb96c565437bbba92e419781f5e 395 Gene3D G3DSA:1.20.1530.20 1 394 5.7E-77 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TAM4_302 de154eb96c565437bbba92e419781f5e 395 Pfam PF00999 Sodium/hydrogen exchanger family 8 382 3.0E-53 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TAM4_474 168008a0df448c10fd0be44df72925ad 177 Pfam PF01899 Na+/H+ ion antiporter subunit 15 160 2.5E-45 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_474 168008a0df448c10fd0be44df72925ad 177 PIRSF PIRSF019239 4 177 3.2E-54 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 SUPERFAMILY SSF46785 252 310 8.88E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 Gene3D G3DSA:3.40.50.300 12 164 3.4E-8 T 23-10-2018 TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 Gene3D G3DSA:1.10.10.10 251 309 1.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 SMART SM00382 46 166 2.1E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 SUPERFAMILY SSF52540 47 198 7.63E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_948 a7869e0f1619c1a1649124227d4ae1ac 430 Pfam PF13173 AAA domain 47 171 1.1E-24 T 23-10-2018 TAM4_2337 e5e3737df869bfd4233a94dca51d660f 211 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 198 9.2E-52 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 Pfam PF00209 Sodium:neurotransmitter symporter family 159 520 4.4E-22 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 8.7E-19 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 SUPERFAMILY SSF161070 4 535 5.62E-98 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 381 400 1.3E-10 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.3E-10 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TAM4_1590 8b74bfcf9c7b1a1ba2a8dae52818d57d 562 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.3E-10 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TAM4_1393 076b2e1f15de9845016773f06f5a3d80 505 Gene3D G3DSA:1.25.10.10 2 262 2.8E-22 T 23-10-2018 IPR011989 Armadillo-like helical TAM4_1393 076b2e1f15de9845016773f06f5a3d80 505 SUPERFAMILY SSF48371 30 436 3.41E-33 T 23-10-2018 IPR016024 Armadillo-type fold TAM4_1393 076b2e1f15de9845016773f06f5a3d80 505 Gene3D G3DSA:1.25.10.10 279 467 2.7E-7 T 23-10-2018 IPR011989 Armadillo-like helical TAM4_1817 cb343a5e92ae7861a1889b7fd3768ee6 325 Pfam PF12679 ABC-2 family transporter protein 6 324 8.0E-32 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TAM4_388 dbacb2155299a79522c2b80e9b194507 171 Pfam PF05763 Protein of unknown function (DUF835) 40 165 1.9E-38 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_1785 4d47e05f9e61f51a2efeb01b2cf068d0 399 Pfam PF07690 Major Facilitator Superfamily 18 345 1.3E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1785 4d47e05f9e61f51a2efeb01b2cf068d0 399 Gene3D G3DSA:1.20.1250.20 5 383 1.2E-24 T 23-10-2018 TAM4_1785 4d47e05f9e61f51a2efeb01b2cf068d0 399 SUPERFAMILY SSF103473 11 380 8.11E-27 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_1032 57aa575312292aeff609b06de5ce8da9 66 Pfam PF10133 Predicted RNA-binding protein 1 61 1.4E-15 T 23-10-2018 IPR019300 RNA-binding protein, predicted TAM4_557 ac38c6719f6038cebbe356c9715586fe 136 SUPERFAMILY SSF101307 6 134 2.35E-34 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 TAM4_557 ac38c6719f6038cebbe356c9715586fe 136 Pfam PF04608 Phosphatidylglycerophosphatase A 15 133 5.4E-10 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 TAM4_557 ac38c6719f6038cebbe356c9715586fe 136 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 8 134 3.8E-53 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ TAM4_557 ac38c6719f6038cebbe356c9715586fe 136 Gene3D G3DSA:1.10.3760.10 2 135 3.1E-11 T 23-10-2018 TAM4_1743 55877238c9cf1d2fa9da279463391722 535 Pfam PF03553 Na+/H+ antiporter family 156 490 8.0E-77 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TAM4_974 7ff898c967e825a5f31e60a86f1a46df 237 Gene3D G3DSA:3.40.50.300 7 235 4.1E-57 T 23-10-2018 TAM4_974 7ff898c967e825a5f31e60a86f1a46df 237 Pfam PF06745 KaiC 13 234 1.5E-49 T 23-10-2018 IPR014774 KaiC-like domain TAM4_974 7ff898c967e825a5f31e60a86f1a46df 237 SUPERFAMILY SSF52540 8 233 1.46E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_982 890beb2840d4a04e63f3cc29a121d925 99 SUPERFAMILY SSF88723 23 85 7.29E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_982 890beb2840d4a04e63f3cc29a121d925 99 Pfam PF01850 PIN domain 4 72 1.7E-5 T 23-10-2018 IPR002716 PIN domain TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 Pfam PF01280 Ribosomal protein L19e 2 143 4.3E-59 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 Gene3D G3DSA:1.10.1200.240 56 147 2.6E-30 T 23-10-2018 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 SUPERFAMILY SSF48140 1 141 9.55E-58 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 SMART SM01416 1 144 2.3E-89 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 26.067 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_283 5e5984390038e5b08b7650ba9c61aade 148 Gene3D G3DSA:1.10.1650.10 1 54 1.6E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_1404 b1fa71de4f4d7bd5d8043b500c5198c0 144 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 4 130 6.2E-27 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TAM4_879 f9546d3def486394064261bad39c6505 401 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 398 2.1E-66 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_879 f9546d3def486394064261bad39c6505 401 PIRSF PIRSF006603 3 401 9.9E-137 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_879 f9546d3def486394064261bad39c6505 401 Pfam PF01554 MatE 28 188 1.9E-30 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_879 f9546d3def486394064261bad39c6505 401 Pfam PF01554 MatE 249 393 6.3E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TAM4_1059 85851147e5d39e86814add89c1a24771 269 Gene3D G3DSA:3.40.50.300 1 261 2.9E-53 T 23-10-2018 TAM4_1059 85851147e5d39e86814add89c1a24771 269 PIRSF PIRSF005647 1 264 2.3E-61 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type TAM4_1059 85851147e5d39e86814add89c1a24771 269 SUPERFAMILY SSF52540 3 262 1.74E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1059 85851147e5d39e86814add89c1a24771 269 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 237 3.6E-14 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TAM4_1609 f1f7f6b504ae5c42d7dd44243ae1c8b4 347 Gene3D G3DSA:3.60.70.12 1 346 5.3E-136 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TAM4_1609 f1f7f6b504ae5c42d7dd44243ae1c8b4 347 SUPERFAMILY SSF56266 2 344 1.15E-98 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TAM4_1609 f1f7f6b504ae5c42d7dd44243ae1c8b4 347 Pfam PF03576 Peptidase family S58 19 324 9.9E-109 T 23-10-2018 IPR005321 Peptidase S58, DmpA TAM4_1543 53738994a39c7df3ad17ff83d1edefcf 289 SUPERFAMILY SSF103481 46 146 1.96E-12 T 23-10-2018 TAM4_1543 53738994a39c7df3ad17ff83d1edefcf 289 SUPERFAMILY SSF103481 188 287 6.93E-15 T 23-10-2018 TAM4_1543 53738994a39c7df3ad17ff83d1edefcf 289 Pfam PF00892 EamA-like transporter family 153 287 4.8E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1543 53738994a39c7df3ad17ff83d1edefcf 289 Pfam PF00892 EamA-like transporter family 6 141 6.4E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TAM4_1383 58152fb71c94df2785eceb872d5ebe26 349 Gene3D G3DSA:3.40.50.300 4 198 3.0E-31 T 23-10-2018 TAM4_1383 58152fb71c94df2785eceb872d5ebe26 349 Gene3D G3DSA:1.10.8.60 199 275 6.3E-16 T 23-10-2018 TAM4_1383 58152fb71c94df2785eceb872d5ebe26 349 Pfam PF01637 ATPase domain predominantly from Archaea 17 238 5.7E-15 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TAM4_1383 58152fb71c94df2785eceb872d5ebe26 349 SUPERFAMILY SSF52540 4 250 2.7E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1874 b70a41e26b1237c68534b25a413583fa 116 Pfam PF03008 Archaea bacterial proteins of unknown function 1 66 1.7E-23 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TAM4_1874 b70a41e26b1237c68534b25a413583fa 116 SUPERFAMILY SSF52980 2 77 1.47E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TAM4_457 e15b4bb41d4765490bdd58787f4e4ca2 204 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 44 200 8.9E-38 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family TAM4_457 e15b4bb41d4765490bdd58787f4e4ca2 204 Gene3D G3DSA:3.90.1720.10 44 202 1.1E-14 T 23-10-2018 TAM4_457 e15b4bb41d4765490bdd58787f4e4ca2 204 SUPERFAMILY SSF54001 43 201 1.44E-25 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TAM4_1808 4a44586ad0d61af2def1801ae646ae47 383 Gene3D G3DSA:1.10.390.60 180 383 8.4E-11 T 23-10-2018 TAM4_1808 4a44586ad0d61af2def1801ae646ae47 383 SUPERFAMILY SSF55486 188 383 8.06E-13 T 23-10-2018 TAM4_1754 65dc6fa2548869ab07d7330bd1a52dac 194 SUPERFAMILY SSF52833 28 109 1.12E-8 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TAM4_1754 65dc6fa2548869ab07d7330bd1a52dac 194 Gene3D G3DSA:3.40.30.10 26 116 1.9E-6 T 23-10-2018 TAM4_1754 65dc6fa2548869ab07d7330bd1a52dac 194 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 174 193 1.1E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_2029 ff94523b42ee7078f88d41058df4ffa5 165 Pfam PF01899 Na+/H+ ion antiporter subunit 11 163 1.1E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_2029 ff94523b42ee7078f88d41058df4ffa5 165 PIRSF PIRSF019239 1 165 1.2E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_1075 b0bdeffc5ae4eb228b80c61791fd61d6 176 Gene3D G3DSA:3.30.300.130 72 176 2.2E-36 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TAM4_1075 b0bdeffc5ae4eb228b80c61791fd61d6 176 SUPERFAMILY SSF117916 77 174 1.6E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TAM4_1075 b0bdeffc5ae4eb228b80c61791fd61d6 176 Pfam PF01883 Iron-sulfur cluster assembly protein 80 153 1.3E-21 T 23-10-2018 IPR002744 MIP18 family-like TAM4_69 01b90272d63276ca822d21d049e7a3b1 152 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 141 8.3E-9 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TAM4_1131 45d7f1413703c308a1024a206181ccf9 231 Pfam PF00899 ThiF family 10 230 3.2E-55 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TAM4_1131 45d7f1413703c308a1024a206181ccf9 231 Gene3D G3DSA:3.40.50.720 2 231 2.1E-70 T 23-10-2018 TAM4_1131 45d7f1413703c308a1024a206181ccf9 231 SUPERFAMILY SSF69572 3 226 7.72E-78 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TAM4_1144 d36f78a2b1237813048e5f6853a394bc 181 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 101 1.2E-25 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative TAM4_1144 d36f78a2b1237813048e5f6853a394bc 181 Gene3D G3DSA:1.10.10.60 55 83 5.1E-6 T 23-10-2018 TAM4_649 49e582b31d70c6438e99995dd7a98e3f 198 Gene3D G3DSA:3.30.420.130 1 116 4.9E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_649 49e582b31d70c6438e99995dd7a98e3f 198 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 105 3.6E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TAM4_649 49e582b31d70c6438e99995dd7a98e3f 198 SUPERFAMILY SSF53146 1 113 1.01E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TAM4_430 0687d6aaa9bee9909a7eb3c7a2d16094 217 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 198 217 3.9E-8 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_533 a1d263920f649ca15f59000c8326fd5c 138 Gene3D G3DSA:3.30.1440.10 1 137 6.0E-44 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_533 a1d263920f649ca15f59000c8326fd5c 138 SUPERFAMILY SSF55282 7 137 1.85E-39 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_533 a1d263920f649ca15f59000c8326fd5c 138 Hamap MF_01112 UPF0201 protein . 6 135 24.819 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TAM4_533 a1d263920f649ca15f59000c8326fd5c 138 Pfam PF01877 RNA binding 7 116 8.5E-17 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TAM4_587 ac02940e5bac578e925b9f110f0e6dcd 263 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 139 261 4.0E-44 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TAM4_587 ac02940e5bac578e925b9f110f0e6dcd 263 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 6 93 1.0E-21 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TAM4_587 ac02940e5bac578e925b9f110f0e6dcd 263 Pfam PF10869 Protein of unknown function (DUF2666) 6 121 9.2E-13 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TAM4_587 ac02940e5bac578e925b9f110f0e6dcd 263 Pfam PF10869 Protein of unknown function (DUF2666) 139 261 1.8E-41 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TAM4_563 478e25c48becdd7565254f1df7ac2d1c 189 Pfam PF01944 Stage II sporulation protein M 23 184 3.0E-29 T 23-10-2018 IPR002798 Stage II sporulation protein M-like TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 93 1.7E-15 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 96 134 6.3E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 45.444 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 1.7E-11 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 Gene3D G3DSA:3.30.420.100 1 197 1.3E-72 T 23-10-2018 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 SUPERFAMILY SSF53137 2 195 9.94E-64 T 23-10-2018 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 2.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 2.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_319 e7449a7e14061ec6ac1b1eec46df21d2 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 2.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TAM4_242 8339594c37e6ab0c7126b849c8f7d544 84 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 61 1.8E-10 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal TAM4_1956 bd8e39df8324b0e008e363e6bd22ef7b 440 Gene3D G3DSA:3.30.2290.10 2 208 3.7E-15 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TAM4_1956 bd8e39df8324b0e008e363e6bd22ef7b 440 Pfam PF01523 Putative modulator of DNA gyrase 22 303 3.5E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TAM4_1956 bd8e39df8324b0e008e363e6bd22ef7b 440 SUPERFAMILY SSF111283 2 436 1.22E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TAM4_1584 30d1d44e94e2ad1138ff57470300a394 129 SUPERFAMILY SSF143100 56 106 6.8E-6 T 23-10-2018 IPR035069 TTHA1013/TTHA0281-like TAM4_1042 ebb201950d6df384ba3e7c5eb98b9272 578 SUPERFAMILY SSF48239 33 469 7.49E-24 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TAM4_1042 ebb201950d6df384ba3e7c5eb98b9272 578 Gene3D G3DSA:1.50.10.20 26 143 2.7E-10 T 23-10-2018 TAM4_1526 91a104015f9387acb4f04914a7d0ee8e 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 330 4.0E-43 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TAM4_654 53cde4b94de66fdd28fa865f912cd225 126 Gene3D G3DSA:1.20.120.330 1 125 1.8E-35 T 23-10-2018 TAM4_654 53cde4b94de66fdd28fa865f912cd225 126 Pfam PF05168 HEPN domain 11 120 2.6E-24 T 23-10-2018 IPR007842 HEPN domain TAM4_1959 14fc76d51a559670fb4ff43d05e0a3df 74 Pfam PF10049 Protein of unknown function (DUF2283) 4 50 3.6E-17 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 TAM4_2123 e865ca2775d412148dd3d8d7ad04b244 192 SMART SM00014 82 185 1.9E-5 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TAM4_2123 e865ca2775d412148dd3d8d7ad04b244 192 Gene3D G3DSA:1.20.144.10 117 188 4.6E-11 T 23-10-2018 TAM4_2123 e865ca2775d412148dd3d8d7ad04b244 192 SUPERFAMILY SSF48317 9 184 2.49E-28 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TAM4_2123 e865ca2775d412148dd3d8d7ad04b244 192 Pfam PF01569 PAP2 superfamily 83 177 1.2E-14 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TAM4_2201 e78e77651840753348c2eab69aa4c9ee 255 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 115 239 1.7E-16 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TAM4_620 b2d43a7546a553582672557ab59223c5 54 Pfam PF04021 Class III signal peptide 2 27 8.7E-9 T 23-10-2018 IPR007166 Class III signal peptide motif TAM4_1904 3760a3651d2a150f15149c2f5c00154e 335 Pfam PF01594 AI-2E family transporter 12 324 3.0E-40 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TAM4_1139 bd6fe63964f7bc3c339f73c78f0aba3c 305 Pfam PF00146 NADH dehydrogenase 14 293 2.1E-43 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1139 bd6fe63964f7bc3c339f73c78f0aba3c 305 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 191 204 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1336 ebf0294ff6251b5649ee2f11b0254127 171 Pfam PF03692 Putative zinc- or iron-chelating domain 16 126 2.6E-18 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TAM4_320 6f2ca87a9f7b7a077915a1c74b68c825 765 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 144 473 3.9E-55 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TAM4_320 6f2ca87a9f7b7a077915a1c74b68c825 765 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 61 478 1.9E-110 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TAM4_269 e87ad82a921a53a7b4060db3ed438f21 439 Gene3D G3DSA:1.25.40.10 8 270 2.4E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_269 e87ad82a921a53a7b4060db3ed438f21 439 Gene3D G3DSA:1.25.40.10 295 412 2.8E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_836 f3db092a17e65356d54739a9493450c1 258 SUPERFAMILY SSF52317 19 240 2.59E-29 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_836 f3db092a17e65356d54739a9493450c1 258 Pfam PF07722 Peptidase C26 11 218 1.2E-47 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TAM4_836 f3db092a17e65356d54739a9493450c1 258 Gene3D G3DSA:3.40.50.880 1 247 1.5E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TAM4_2367 92a27e5ddcb818d2255c7d8927fb32fc 73 Gene3D G3DSA:3.30.300.130 1 66 1.5E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TAM4_297 8681904f8d9e61f2916e06d96fbc97ef 171 Pfam PF01864 CDP-archaeol synthase 7 171 4.7E-59 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TAM4_297 8681904f8d9e61f2916e06d96fbc97ef 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 27.906 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TAM4_1555 20e9f25b46067843cc618f13fbb99f92 364 Pfam PF05763 Protein of unknown function (DUF835) 235 362 7.4E-26 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TAM4_144 d5c4efde9f6ac17803e8ab83348e8423 388 Gene3D G3DSA:3.40.50.300 2 185 5.9E-14 T 23-10-2018 TAM4_448 18abfa9ce336aa9b956177cb07a5b6df 432 Pfam PF13173 AAA domain 34 164 4.1E-33 T 23-10-2018 TAM4_448 18abfa9ce336aa9b956177cb07a5b6df 432 SUPERFAMILY SSF52540 33 167 4.13E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_448 18abfa9ce336aa9b956177cb07a5b6df 432 Pfam PF13635 Domain of unknown function (DUF4143) 252 359 1.1E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TAM4_1156 1822f870ae54591e8aacabc4e1c7ea32 467 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 306 384 7.9E-8 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TAM4_34 ecb67f9b1c519b0cb37ceb37a495cfdc 191 SUPERFAMILY SSF52540 1 187 2.88E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_34 ecb67f9b1c519b0cb37ceb37a495cfdc 191 Pfam PF13238 AAA domain 3 138 3.5E-18 T 23-10-2018 TAM4_34 ecb67f9b1c519b0cb37ceb37a495cfdc 191 Gene3D G3DSA:3.40.50.300 1 189 2.4E-43 T 23-10-2018 TAM4_2073 1a05750ae558ec0f98e850c6e9627f2f 85 Pfam PF13244 Domain of unknown function (DUF4040) 18 80 7.1E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TAM4_413 7745e78965b41b8d49732bd77b828274 194 SUPERFAMILY SSF54001 38 190 1.47E-29 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TAM4_413 7745e78965b41b8d49732bd77b828274 194 Gene3D G3DSA:3.90.1720.10 50 167 2.0E-15 T 23-10-2018 TAM4_413 7745e78965b41b8d49732bd77b828274 194 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 38 190 3.0E-27 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family TAM4_699 f92d6e50f9b95062e382f2d6277f4d25 97 SUPERFAMILY SSF88723 13 80 5.05E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_699 f92d6e50f9b95062e382f2d6277f4d25 97 Gene3D G3DSA:3.40.50.1010 2 78 1.5E-6 T 23-10-2018 TAM4_1731 55c35b561608d25ce9c3cc0a6085d950 157 Pfam PF01917 Archaebacterial flagellin 5 152 2.0E-23 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_1815 0511f22dee12687773e755d0532c6b56 412 PIRSF PIRSF018871 179 412 3.0E-34 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TAM4_1815 0511f22dee12687773e755d0532c6b56 412 PIRSF PIRSF018871 1 189 4.1E-40 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TAM4_1815 0511f22dee12687773e755d0532c6b56 412 SMART SM00933 45 377 2.6E-16 T 23-10-2018 IPR018977 NurA domain TAM4_1815 0511f22dee12687773e755d0532c6b56 412 Pfam PF09376 NurA domain 46 377 1.1E-33 T 23-10-2018 IPR018977 NurA domain TAM4_148 539f4ed8edebb86c545aa739e7513af1 196 Pfam PF13207 AAA domain 8 145 1.7E-35 T 23-10-2018 TAM4_148 539f4ed8edebb86c545aa739e7513af1 196 SUPERFAMILY SSF52540 1 188 1.49E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_148 539f4ed8edebb86c545aa739e7513af1 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.084 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TAM4_148 539f4ed8edebb86c545aa739e7513af1 196 Gene3D G3DSA:3.40.50.300 3 189 1.6E-55 T 23-10-2018 TAM4_1258 6cc55111d656f0bdfc9ea528adcf6461 911 Gene3D G3DSA:2.60.40.10 488 569 4.0E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1780 af4cd4241d74feae61de30861ec88ea5 163 SUPERFAMILY SSF159234 3 163 2.22E-37 T 23-10-2018 IPR035930 FomD-like superfamily TAM4_1780 af4cd4241d74feae61de30861ec88ea5 163 Gene3D G3DSA:2.40.380.10 7 163 1.0E-15 T 23-10-2018 IPR035930 FomD-like superfamily TAM4_1780 af4cd4241d74feae61de30861ec88ea5 163 Pfam PF04167 Protein of unknown function (DUF402) 56 122 7.2E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TAM4_1770 6e75acd57939e3d445699700502412b2 165 Gene3D G3DSA:1.25.40.10 15 157 3.3E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_167 32fead7bd48aea172ce5bf06bf67c29a 386 SUPERFAMILY SSF103473 9 367 1.31E-26 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_167 32fead7bd48aea172ce5bf06bf67c29a 386 Gene3D G3DSA:1.20.1250.20 207 378 1.5E-7 T 23-10-2018 TAM4_167 32fead7bd48aea172ce5bf06bf67c29a 386 Pfam PF07690 Major Facilitator Superfamily 13 343 2.0E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_167 32fead7bd48aea172ce5bf06bf67c29a 386 Gene3D G3DSA:1.20.1250.20 2 198 1.9E-13 T 23-10-2018 TAM4_1928 7e1ed57d3399d08caa3a4edcc31b04a5 172 Gene3D G3DSA:3.30.460.10 44 136 6.0E-14 T 23-10-2018 TAM4_1928 7e1ed57d3399d08caa3a4edcc31b04a5 172 SUPERFAMILY SSF81301 56 138 8.05E-16 T 23-10-2018 TAM4_1928 7e1ed57d3399d08caa3a4edcc31b04a5 172 Pfam PF01909 Nucleotidyltransferase domain 50 117 1.2E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TAM4_1204 2ebc582a7f23e2a3eeaf0946b0a37ab6 662 Pfam PF04312 Protein of unknown function (DUF460) 209 349 2.1E-49 T 23-10-2018 IPR007408 Protein of unknown function DUF460 TAM4_726 11fa73f0d8d330c73820635eacdb9d40 265 ProDom PD039347 PF1398 MJ0538 PH1392 9 246 6.0E-23 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 TAM4_225 5bacf842d426e14292822d41e3796d74 137 Gene3D G3DSA:3.30.110.150 53 137 4.9E-27 T 23-10-2018 IPR038594 SepF-like superfamily TAM4_225 5bacf842d426e14292822d41e3796d74 137 Pfam PF04472 Cell division protein SepF 60 135 5.9E-15 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TAM4_225 5bacf842d426e14292822d41e3796d74 137 PIRSF PIRSF019313 1 137 1.5E-28 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea TAM4_2093 31c12f7ab33531bd37885838ed3d57c7 57 SUPERFAMILY SSF141694 1 54 2.38E-14 T 23-10-2018 TAM4_2093 31c12f7ab33531bd37885838ed3d57c7 57 Gene3D G3DSA:4.10.1150.10 1 56 2.8E-13 T 23-10-2018 IPR024069 AF2212-like domain superfamily TAM4_2093 31c12f7ab33531bd37885838ed3d57c7 57 Pfam PF01954 Protein of unknown function DUF104 1 34 4.2E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 SUPERFAMILY SSF103473 7 400 4.05E-40 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 9 374 1.8E-102 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 Gene3D G3DSA:1.20.1250.20 5 397 1.5E-35 T 23-10-2018 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 48 66 3.2E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 137 158 3.2E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 74 92 3.2E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 164 181 3.2E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 295 318 3.2E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TAM4_2071 d45d02ca1f20253d0d6d260cf17afc13 420 Pfam PF07690 Major Facilitator Superfamily 13 364 5.6E-29 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_1804 563e2f1638f950221e3303e6a4580634 93 SUPERFAMILY SSF88723 2 91 3.64E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily TAM4_1804 563e2f1638f950221e3303e6a4580634 93 Gene3D G3DSA:3.40.50.1010 1 89 4.3E-14 T 23-10-2018 TAM4_1804 563e2f1638f950221e3303e6a4580634 93 Pfam PF01850 PIN domain 2 85 3.2E-11 T 23-10-2018 IPR002716 PIN domain TAM4_1996 bcfd223841cccd9dea16cece401c1bfb 442 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 348 2.6E-16 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_1996 bcfd223841cccd9dea16cece401c1bfb 442 Pfam PF07282 Putative transposase DNA-binding domain 323 391 4.5E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TAM4_1283 4a8671e4163ad95a287fc2b218adcf3c 93 SUPERFAMILY SSF143011 2 89 2.49E-14 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_1283 4a8671e4163ad95a287fc2b218adcf3c 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 46 92 1.0E-5 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TAM4_1283 4a8671e4163ad95a287fc2b218adcf3c 93 Gene3D G3DSA:3.30.2310.20 1 93 1.7E-23 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TAM4_359 5a03842cf87a073cefa7c79547e2d70b 110 Pfam PF14333 Domain of unknown function (DUF4389) 5 77 9.7E-18 T 23-10-2018 IPR025498 Protein of unknown function DUF4389 TAM4_509 d9ae09dd1034ef58ff5808d84b754791 249 Gene3D G3DSA:3.40.50.300 1 249 2.3E-74 T 23-10-2018 TAM4_1522 7ccc43e185bbd5707f91ed9d385796fb 362 Pfam PF01988 VIT family 145 351 1.8E-46 T 23-10-2018 IPR008217 Ccc1 family TAM4_1522 7ccc43e185bbd5707f91ed9d385796fb 362 SUPERFAMILY SSF47240 4 139 4.4E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily TAM4_1005 abfc0a4e7bfa5f0a19078561afaa12c6 445 SUPERFAMILY SSF50965 85 371 2.88E-5 T 23-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller TAM4_1563 921b6144865bd5d1ce531352cd258250 652 SUPERFAMILY SSF49464 375 437 1.73E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TAM4_1244 430f5b3876d22a9052054bcace4b2a9c 246 Hamap MF_02040 Iron-sulfur cluster carrier protein. 11 240 28.239 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TAM4_1244 430f5b3876d22a9052054bcace4b2a9c 246 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 15 235 5.9E-58 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TAM4_1244 430f5b3876d22a9052054bcace4b2a9c 246 Gene3D G3DSA:3.40.50.300 1 228 2.6E-70 T 23-10-2018 TAM4_1244 430f5b3876d22a9052054bcace4b2a9c 246 SUPERFAMILY SSF52540 17 228 4.54E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TAM4_1169 34824ea588d359cc1cd27a20e8c71cae 279 SUPERFAMILY SSF55681 30 276 1.12E-68 T 23-10-2018 TAM4_1169 34824ea588d359cc1cd27a20e8c71cae 279 Gene3D G3DSA:3.30.930.10 37 279 4.1E-62 T 23-10-2018 TAM4_1169 34824ea588d359cc1cd27a20e8c71cae 279 Pfam PF03099 Biotin/lipoate A/B protein ligase family 80 187 4.9E-13 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TAM4_2120 4569e1e5e7ee77ba7257bb1540a2f306 217 Pfam PF13349 Putative adhesin 100 214 8.1E-10 T 23-10-2018 IPR025164 Putative adhesin TAM4_2006 2b581aab82765e6a92667889d4953186 319 SUPERFAMILY SSF50952 4 309 5.75E-11 T 23-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TAM4_2006 2b581aab82765e6a92667889d4953186 319 Gene3D G3DSA:2.130.10.10 8 311 4.7E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TAM4_2207 b109fa5369fe5e84a48e15c68159ce76 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 77 3.3E-24 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 TAM4_497 20308301af88ef091ef46624b1be4e66 428 SUPERFAMILY SSF48452 9 211 5.48E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_497 20308301af88ef091ef46624b1be4e66 428 Gene3D G3DSA:1.25.40.10 2 223 5.4E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_497 20308301af88ef091ef46624b1be4e66 428 Gene3D G3DSA:1.25.40.10 230 407 1.0E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_187 cb7edbbebb99e3ec13b37dbc678f49d0 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 1.3E-121 T 23-10-2018 IPR008482 Protein of unknown function DUF763 TAM4_977 b7d2603edad21ab7eceb2c90a8ed41e3 137 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 1 66 3.6E-21 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 TAM4_84 e59d277b87faa56876ff6da3ff95cdf3 208 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 187 205 1.7E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_579 9543c039a63d9e6e2bcd4aaf859d8f40 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_579 9543c039a63d9e6e2bcd4aaf859d8f40 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TAM4_579 9543c039a63d9e6e2bcd4aaf859d8f40 367 Pfam PF17179 4Fe-4S dicluster domain 232 326 9.6E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TAM4_579 9543c039a63d9e6e2bcd4aaf859d8f40 367 SUPERFAMILY SSF46548 217 330 5.75E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TAM4_555 bff0e6ef22c00975db4f5ccb62ec9d3c 701 SUPERFAMILY SSF51126 207 434 6.59E-5 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor TAM4_919 1c72a8346aea5d77c0a0722a5380f254 197 Pfam PF03773 Predicted permease 58 183 1.1E-11 T 23-10-2018 IPR005524 Predicted permease DUF318 TAM4_1806 a2f8adda78f9612497f728e17759dcb1 256 Pfam PF13559 Domain of unknown function (DUF4129) 183 248 1.1E-7 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 TAM4_674 5ea9a9dd5c46eba500506dfbb85424c0 102 Gene3D G3DSA:3.30.720.70 1 102 1.1E-51 T 23-10-2018 TAM4_415 de64c102f5bdf6551ea17f0d79613704 425 Pfam PF13529 Peptidase_C39 like family 248 381 9.7E-6 T 23-10-2018 IPR039564 Peptidase C39-like TAM4_235 b3a77553ba9524ec821ba42bb1ca7b2b 233 Pfam PF07758 Protein of unknown function (DUF1614) 55 232 1.9E-55 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 TAM4_1000 1f3a9119042f223bcef2ee9d53e9df46 325 Pfam PF13026 Protein of unknown function (DUF3887) 24 110 4.6E-7 T 23-10-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 TAM4_1894 080f5f2714455883503a82bd7c1001ce 629 Pfam PF00361 Proton-conducting membrane transporter 121 409 1.4E-26 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_693 000e6487a3c2fcd805d488ae5e149e03 525 Gene3D G3DSA:2.60.40.10 307 383 2.5E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_693 000e6487a3c2fcd805d488ae5e149e03 525 Pfam PF13620 Carboxypeptidase regulatory-like domain 316 392 5.5E-9 T 23-10-2018 TAM4_693 000e6487a3c2fcd805d488ae5e149e03 525 SUPERFAMILY SSF49464 319 395 1.29E-9 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TAM4_1846 b79127356323e526b002c41f1fbc55d4 229 Gene3D G3DSA:1.10.10.10 9 94 7.4E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TAM4_1846 b79127356323e526b002c41f1fbc55d4 229 SUPERFAMILY SSF46785 16 98 3.89E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1846 b79127356323e526b002c41f1fbc55d4 229 Pfam PF12840 Helix-turn-helix domain 17 71 2.8E-10 T 23-10-2018 TAM4_1414 ef50d44aa1c9df9f42f194c2389e1053 148 SUPERFAMILY SSF81301 3 120 3.2E-8 T 23-10-2018 TAM4_1414 ef50d44aa1c9df9f42f194c2389e1053 148 Gene3D G3DSA:3.30.460.10 1 121 5.2E-9 T 23-10-2018 TAM4_1282 78be515d33617a52afed619476a4c289 151 Pfam PF11848 Domain of unknown function (DUF3368) 103 142 7.7E-15 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_752 c93b81dd3d704f53ad7bb2cb5b4a7a66 241 Pfam PF01940 Integral membrane protein DUF92 14 219 5.0E-48 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 TAM4_31 5820f394ef4b3c46f39c1d85703c6725 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 6 90 5.8E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding TAM4_1289 7183e0716109cdcd29f7c9174ad283ba 167 PIRSF PIRSF019239 1 165 5.3E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_1289 7183e0716109cdcd29f7c9174ad283ba 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 164 1.8E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TAM4_2314 654bd8f1384b45b6e5cb9bcbc09abf31 252 Pfam PF12730 ABC-2 family transporter protein 71 190 1.2E-6 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TAM4_2446 b47f7f06b5d48f7ce91de457e7a20473 320 Pfam PF01384 Phosphate transporter family 19 307 1.6E-69 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TAM4_1832 f12ae37881d0841ff25877e0f66243f9 220 Pfam PF01863 Protein of unknown function DUF45 13 203 1.6E-45 T 23-10-2018 IPR002725 Protein of unknown function DUF45 TAM4_1832 f12ae37881d0841ff25877e0f66243f9 220 Gene3D G3DSA:3.30.2010.10 113 206 7.7E-20 T 23-10-2018 TAM4_1048 33b20746e46e1eb749d6741e2acc5847 521 Pfam PF00361 Proton-conducting membrane transporter 132 438 4.6E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1291 1bd628d35301124d79c5d9fd02eac9b3 414 Pfam PF01882 Protein of unknown function DUF58 194 273 1.3E-21 T 23-10-2018 IPR002881 Domain of unknown function DUF58 TAM4_1079 16297c62f858ee831fad665acc0d209c 2607 Gene3D G3DSA:2.60.40.10 2222 2301 2.5E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold TAM4_1079 16297c62f858ee831fad665acc0d209c 2607 SUPERFAMILY SSF49464 2306 2392 1.49E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TAM4_1093 a6a00dd78791a75a4ad380d8f957fbb3 145 SUPERFAMILY SSF46785 3 58 2.83E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TAM4_1011 d4f9071dd985c63a6f7b39d5b589f0c8 168 Pfam PF06510 Protein of unknown function (DUF1102) 27 166 2.5E-51 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 TAM4_749 3b9caaec070c3be6d1ee63dd4cac208d 187 Pfam PF06195 Protein of unknown function (DUF996) 92 157 1.0E-11 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TAM4_749 3b9caaec070c3be6d1ee63dd4cac208d 187 Pfam PF06195 Protein of unknown function (DUF996) 42 89 1.8E-8 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TAM4_560 74f205b9b8db7fdf24ed0f42cb304a27 476 Pfam PF10102 Domain of unknown function (DUF2341) 193 273 1.7E-19 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TAM4_236 3d0d7925c0565433065606bac65f8bc2 87 Pfam PF01169 Uncharacterized protein family UPF0016 9 79 1.0E-22 T 23-10-2018 IPR001727 Gdt1 family TAM4_1565 864fb904520e907c2c21bcaac9e5022f 387 SUPERFAMILY SSF48452 56 132 1.14E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1565 864fb904520e907c2c21bcaac9e5022f 387 Gene3D G3DSA:1.25.40.10 1 350 4.1E-60 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TAM4_1576 8a61ad881b4b342093067b4ce164359f 478 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 457 476 1.2E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TAM4_918 777a401ce81b7e9f2b105e6edcff8c69 118 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 115 3.7E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TAM4_1381 fd06fa207a2eb14d7592529fcb9e7b1a 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 1.2E-20 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TAM4_729 7240b3db0894eb943cef7103836d4d95 243 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 2.5E-54 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TAM4_2458 2159b305af75e543c4a23fa54d68863f 84 Pfam PF13244 Domain of unknown function (DUF4040) 17 80 3.5E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TAM4_1577 d8dda151b22fb7a434b74bae276390f0 107 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 16 48 7.3E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 TAM4_2348 3a7836f8860426f0f4cca36fa9ad766d 187 Pfam PF02163 Peptidase family M50 123 167 1.9E-6 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_1363 49fb3026a57affe388dfd6563d0b0bf5 103 SUPERFAMILY SSF81573 35 88 1.11E-6 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TAM4_1363 49fb3026a57affe388dfd6563d0b0bf5 103 Gene3D G3DSA:1.20.5.620 41 91 1.5E-5 T 23-10-2018 TAM4_1363 49fb3026a57affe388dfd6563d0b0bf5 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 2.3E-17 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H TAM4_458 3dd1310da195eaf137ecfb65767d1a85 567 Pfam PF04458 Protein of unknown function (DUF505) 1 300 1.7E-74 T 23-10-2018 IPR007548 Protein of unknown function DUF505 TAM4_458 3dd1310da195eaf137ecfb65767d1a85 567 Pfam PF04458 Protein of unknown function (DUF505) 306 566 1.2E-80 T 23-10-2018 IPR007548 Protein of unknown function DUF505 TAM4_936 4b25ac29edb57f9f0dbe96e7ecb57ee0 207 Pfam PF01925 Sulfite exporter TauE/SafE 2 199 2.4E-37 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TAM4_945 e1a43283905ce59d4ba031fe5958472c 291 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 276 5.3E-13 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TAM4_1430 4bdb5b11d9ceade78f22038e8a03b984 812 SUPERFAMILY SSF103647 57 100 5.62E-5 T 23-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TAM4_708 39fc9f1b98ebaa7848d89c41b1968d1a 216 Pfam PF02673 Bacitracin resistance protein BacA 7 207 1.0E-13 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TAM4_900 499d913ebde3f6273fce10554a58c2f2 213 Pfam PF04021 Class III signal peptide 3 28 8.1E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TAM4_143 ce1fd2fe089eb4aafc2b9afe97b55577 122 Gene3D G3DSA:3.40.50.11630 1 122 2.9E-78 T 23-10-2018 TAM4_2465 86f38a105cd490a8813b8b32e6352318 69 Pfam PF10047 Protein of unknown function (DUF2281) 4 59 8.9E-16 T 23-10-2018 IPR018739 Domain of unknown function DUF2281 TAM4_1921 263f1b86c6f42cb789a6f30b148ee645 168 Pfam PF06195 Protein of unknown function (DUF996) 22 144 6.4E-26 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TAM4_808 9ca041f39c04daf86ad465a0bb074023 323 Pfam PF17231 Family of unknown function (DUF5305) 133 320 6.7E-8 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 TAM4_1327 483569145861fa18b611c05d7d6c81f2 481 Pfam PF04415 Protein of unknown function (DUF515) 30 470 6.9E-109 T 23-10-2018 IPR007509 Protein of unknown function DUF515 TAM4_482 e1f599cf726a71cfe90972f05662aa54 251 Pfam PF09874 Predicted membrane protein (DUF2101) 25 232 2.4E-74 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane TAM4_901 403b4060995a726df66876b14da07cfe 196 Pfam PF03956 Lysine exporter LysO 9 191 2.2E-60 T 23-10-2018 IPR005642 Lysine exporter LysO TAM4_901 403b4060995a726df66876b14da07cfe 196 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 7.0E-55 T 23-10-2018 IPR005642 Lysine exporter LysO TAM4_2145 d4885bd9e5876df591a9c8a3f1d9855d 393 SUPERFAMILY SSF103473 23 385 3.53E-30 T 23-10-2018 IPR036259 MFS transporter superfamily TAM4_2145 d4885bd9e5876df591a9c8a3f1d9855d 393 Pfam PF07690 Major Facilitator Superfamily 25 345 3.1E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TAM4_2145 d4885bd9e5876df591a9c8a3f1d9855d 393 Gene3D G3DSA:1.20.1250.20 18 384 5.9E-26 T 23-10-2018 TAM4_1302 902e21b027b7421da9fa7b1e10543fcc 189 SUPERFAMILY SSF57903 134 185 1.8E-5 T 23-10-2018 IPR011011 Zinc finger, FYVE/PHD-type TAM4_543 528ba69f5a089c2928642e6ac4722087 60 Pfam PF04021 Class III signal peptide 2 27 6.6E-7 T 23-10-2018 IPR007166 Class III signal peptide motif TAM4_192 74ab27cd51c387fdf5c00bef8d88ebd5 112 Pfam PF03788 LrgA family 15 106 2.2E-30 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 TAM4_65 bccf71be0a3e113c13194ec0b7c28c10 102 Pfam PF11491 Protein of unknown function (DUF3213) 15 97 3.6E-35 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 TAM4_65 bccf71be0a3e113c13194ec0b7c28c10 102 Gene3D G3DSA:3.30.70.1750 6 101 2.2E-29 T 23-10-2018 TAM4_202 ff768867cd0a07b8a2fde1bf444f34e0 199 Pfam PF12389 Camelysin metallo-endopeptidase 1 98 2.1E-5 T 23-10-2018 IPR022121 Peptidase M73, camelysin TAM4_2173 30124f6a6d97153cab3eafd5289caae1 413 Pfam PF02163 Peptidase family M50 300 341 4.3E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TAM4_794 5f4073f0b7026d79277e1048593a9c51 793 Pfam PF10102 Domain of unknown function (DUF2341) 363 433 2.0E-13 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TAM4_767 c83824c573c807e7a759ce899bf767c6 160 Pfam PF11848 Domain of unknown function (DUF3368) 111 154 7.6E-11 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_422 d8fea81e50fb1d17b251fca9ba6ccbee 120 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 5.8E-24 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 TAM4_1504 36b044a5ee9c074761d33a356a1c01ea 576 Pfam PF00482 Type II secretion system (T2SS), protein F 339 462 7.6E-10 T 23-10-2018 IPR018076 Type II secretion system F domain TAM4_1504 36b044a5ee9c074761d33a356a1c01ea 576 Pfam PF00482 Type II secretion system (T2SS), protein F 89 216 6.0E-9 T 23-10-2018 IPR018076 Type II secretion system F domain TAM4_2354 5a8813f0c555a7ee2d51311eb3657f72 126 Pfam PF09946 Predicted membrane protein (DUF2178) 14 116 1.1E-12 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane TAM4_2385 4ca15f733a6881632a5cce2aed98a331 164 Pfam PF09622 Putative integral membrane protein (DUF2391) 38 159 1.4E-9 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 TAM4_1564 5d94bad8b968817869e06f3e20a2165f 166 Pfam PF01917 Archaebacterial flagellin 4 141 2.2E-8 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TAM4_1229 1ced7147c6bc6511efbe9ee0e29614c7 207 Pfam PF02517 CAAX protease self-immunity 102 193 2.9E-13 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TAM4_677 8c99fbf016d7b0244d7707f9d97bd6f9 258 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 31 157 1.0E-15 T 23-10-2018 TAM4_1063 d4b9af361a72b7ed1ef5880ad24d7811 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 86 4.6E-10 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TAM4_1176 58a047cb2742a50db63990eb77f20040 198 PIRSF PIRSF004897 1 165 6.1E-46 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TAM4_477 42ddb09ec1f23ba69ee476254ccb16c5 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 3.4E-22 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TAM4_2302 d55dddae563cfdfd06e4f2c417009a22 297 Pfam PF00146 NADH dehydrogenase 12 296 9.1E-62 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_1640 988c264270331cca0fea00f62cc2317e 636 Pfam PF16286 Domain of unknown function (DUF4932) 50 229 8.1E-13 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 TAM4_338 0810fb2549bdd6a26b4a43fe73b5922b 68 Pfam PF11848 Domain of unknown function (DUF3368) 19 62 1.1E-9 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 TAM4_963 e62c2d8474aa2c0277c91b15681ab86f 268 Pfam PF02535 ZIP Zinc transporter 123 263 3.8E-19 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TAM4_897 7e6d24f5ca0742acb50f310996c645b4 491 SUPERFAMILY SSF161070 77 411 9.68E-14 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TAM4_1304 6ec605013d3874cfa2156805a138bb34 90 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 2 80 5.2E-15 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 TAM4_2162 9f9a50e7caa95febfd59ea882f8e7366 398 Pfam PF03222 Tryptophan/tyrosine permease family 65 387 5.1E-27 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 TAM4_1275 be4d82324d5d1c2093f65c659c92ce38 328 Pfam PF00146 NADH dehydrogenase 17 321 6.3E-59 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TAM4_130 2431dd7039b057c3203cc008f3ca3f10 713 Pfam PF05753 Translocon-associated protein beta (TRAPB) 344 449 4.0E-6 T 23-10-2018 TAM4_2099 c43672afca5288d0c1506cc456bf46c1 149 Pfam PF06146 Phosphate-starvation-inducible E 60 124 6.1E-15 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like