locus-tag	class	description
K1720_00005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1720_00040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K1720_00045	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
K1720_00050	COG1757	Na H antiporter
K1720_00060	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
K1720_00070	COG1573	uracil-dna glycosylase
K1720_00085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K1720_00095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K1720_00095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K1720_00120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K1720_00125	COG0051	transcription antitermination factor activity, RNA binding
K1720_00140	COG0697	spore germination
K1720_00145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1720_00160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K1720_00160	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
K1720_00185	COG1131	(ABC) transporter
K1720_00195	COG0393	Putative heavy-metal-binding
K1720_00200	COG0315	cyclic pyranopterin monophosphate synthase activity
K1720_00205	COG1193	negative regulation of DNA recombination
K1720_00220	COG1335	isochorismatase
K1720_00225	COG0515	serine threonine protein kinase
K1720_00250	COG1739	Uncharacterized protein family UPF0029
K1720_00255	COG0459	protein refolding
K1720_00260	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K1720_00265	COG5016	pyruvate
K1720_00265	COG0511	ligase activity, forming carbon-carbon bonds
K1720_00275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K1720_00285	COG0305	Participates in initiation and elongation during chromosome replication
K1720_00285	COG1372	Participates in initiation and elongation during chromosome replication
K1720_00305	COG0430	RNA-3'-phosphate cyclase activity
K1720_00355	COG0543	2 iron, 2 sulfur cluster binding
K1720_00360	COG0493	'glutamate synthase
K1720_00360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
K1720_00365	COG0778	Nitroreductase
K1720_00375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K1720_00380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K1720_00420	COG1122	ATPase activity
K1720_00425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K1720_00430	COG0024	Methionine aminopeptidase
K1720_00470	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
K1720_00475	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
K1720_00485	COG1518	maintenance of DNA repeat elements
K1720_00495	COG1203	CRISPR-associated helicase, Cas3
K1720_00550	COG1435	thymidine kinase activity
K1720_00555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K1720_00565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1720_00570	COG0083	homoserine kinase activity
K1720_00575	COG0527	aspartate kinase activity
K1720_00590	COG0165	Argininosuccinate lyase
K1720_00595	COG0505	Belongs to the CarA family
K1720_00615	COG0189	ligase activity
K1720_00620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K1720_00625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K1720_00630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K1720_00635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1720_00640	COG1373	ATPase (AAA superfamily
K1720_00650	COG2379	hydroxypyruvate reductase
K1720_00670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1720_00705	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K1720_00720	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
K1720_00745	COG0574	Belongs to the PEP-utilizing enzyme family
K1720_00745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1720_00755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
K1720_00760	COG2414	aldehyde ferredoxin oxidoreductase
K1720_00770	COG2414	aldehyde ferredoxin oxidoreductase
K1720_00780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K1720_00795	COG0039	L-malate dehydrogenase activity
K1720_00800	COG5441	Belongs to the UPF0261 family
K1720_00805	COG0574	Belongs to the PEP-utilizing enzyme family
K1720_00805	COG3848	Pyruvate phosphate dikinase
K1720_00815	COG0022	dehydrogenase e1 component
K1720_00820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K1720_00830	COG0508	dehydrogenase complex catalyzes the overall conversion of
K1720_00840	COG3199	ATP-NAD kinase
K1720_00845	COG0095	Lipoate-protein ligase
K1720_00855	COG0022	dehydrogenase e1 component
K1720_00860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K1720_00890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1720_00940	COG1160	GTP binding
K1720_00985	COG1606	tRNA processing
K1720_01005	COG1335	isochorismatase
K1720_01020	COG2050	protein possibly involved in aromatic compounds catabolism
K1720_01020	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K1720_01025	COG1695	Transcriptional regulator
K1720_01035	COG0252	asparaginase activity
K1720_01055	COG1185	polyribonucleotide nucleotidyltransferase activity
K1720_01090	COG0463	Glycosyl transferase, family 2
K1720_01095	COG0673	inositol 2-dehydrogenase activity
K1720_01115	COG1176	ABC-type spermidine putrescine transport system, permease component I
K1720_01120	COG3842	ATPase activity
K1720_01140	COG1980	fructose-bisphosphate aldolase activity
K1720_01165	COG1012	belongs to the aldehyde dehydrogenase family
K1720_01185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K1720_01195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K1720_01265	COG0626	cystathionine gamma-synthase activity
K1720_01295	COG2217	Heavy metal translocating P-type atpase
K1720_01325	COG2217	Heavy metal translocating P-type atpase
K1720_01380	COG0450	alkyl hydroperoxide reductase
K1720_01395	COG1522	sequence-specific DNA binding
K1720_01430	COG0719	Fe-S assembly protein
K1720_01440	COG0396	ATPase activity
K1720_01445	COG1528	Iron-storage protein
K1720_01455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K1720_01495	COG0006	proline dipeptidase activity
K1720_01510	COG0426	domain, Protein
K1720_01520	COG1151	hydroxylamine reductase activity
K1720_01580	COG0601	transmembrane transport
K1720_01585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1720_01590	COG0444	Belongs to the ABC transporter superfamily
K1720_01595	COG4608	Belongs to the ABC transporter superfamily
K1720_01615	COG0174	glutamine synthetase
K1720_01655	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K1720_01695	COG2890	protein-(glutamine-N5) methyltransferase activity
K1720_01700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1720_01705	COG1297	OPT oligopeptide transporter protein
K1720_01715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K1720_01725	COG3842	ATPase activity
K1720_01745	COG2182	Extracellular solute-binding protein
K1720_01755	COG1378	Sugar-specific transcriptional regulator TrmB
K1720_01760	COG0297	glycogen (starch) synthase activity
K1720_01770	COG0442	prolyl-tRNA aminoacylation
K1720_01805	COG0482	sulfurtransferase activity
K1720_01810	COG3842	ATPase activity
K1720_01815	COG0395	ABC-type sugar transport system, permease component
K1720_01820	COG1175	transmembrane transport
K1720_01840	COG1394	ATPase activity, coupled to movement of substances
K1720_01850	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
K1720_01855	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
K1720_01875	COG1269	ATP hydrolysis coupled proton transport
K1720_01885	COG0569	domain protein
K1720_01890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K1720_01895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K1720_01895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K1720_01900	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K1720_01910	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K1720_01920	COG1522	sequence-specific DNA binding
K1720_01925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K1720_01945	COG0314	molybdopterin synthase activity
K1720_01950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K1720_01965	COG1510	regulation of RNA biosynthetic process
K1720_02000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K1720_02005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K1720_02015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1720_02015	COG0045	succinate-CoA ligase (ADP-forming) activity
K1720_02015	COG1042	CoA-binding domain protein
K1720_02070	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K1720_02110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K1720_02140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K1720_02190	COG0735	belongs to the Fur family
K1720_02210	COG1174	glycine betaine transport
K1720_02215	COG1174	glycine betaine transport
K1720_02220	COG1125	glycine betaine transport
K1720_02220	COG0517	IMP dehydrogenase activity
K1720_02245	COG2033	superoxide reductase activity
K1720_02250	COG1773	rubredoxin
K1720_02255	COG1592	Rubrerythrin
K1720_02275	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1720_02285	COG0450	alkyl hydroperoxide reductase
K1720_02300	COG0649	NAD binding
K1720_02305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1720_02305	COG0649	NAD binding
K1720_02310	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1720_02315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K1720_02320	COG0651	ATP synthesis coupled electron transport
K1720_02325	COG0651	ATP synthesis coupled electron transport
K1720_02330	COG1006	Multisubunit Na H antiporter MnhC subunit
K1720_02335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K1720_02335	COG2111	Na H antiporter
K1720_02345	COG1320	monovalent cation:proton antiporter activity
K1720_02350	COG2212	antiporter activity
K1720_02355	COG1863	multisubunit Na H antiporter MnhE subunit
K1720_02365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K1720_02380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K1720_02405	COG0018	arginyl-trna synthetase
K1720_02410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K1720_02495	COG0714	Associated with various cellular activities
K1720_02520	COG1047	Peptidyl-prolyl cis-trans
K1720_02565	COG4662	Binding-protein-dependent transport system inner membrane component
K1720_02580	COG0179	Fumarylacetoacetate (FAA) hydrolase
K1720_02595	COG0045	succinate-CoA ligase (ADP-forming) activity
K1720_02595	COG1042	CoA-binding domain protein
K1720_02595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1720_02615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K1720_02615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K1720_02625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K1720_02630	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
K1720_02630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K1720_02635	COG0402	S-adenosylhomocysteine deaminase activity
K1720_02640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K1720_02660	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
K1720_02670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K1720_02695	COG1881	PFAM PEBP family protein
K1720_02740	COG1522	sequence-specific DNA binding
K1720_02755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K1720_02815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K1720_02825	COG0457	Tetratricopeptide repeat
K1720_02830	COG2244	polysaccharide biosynthetic process
K1720_02860	COG3119	arylsulfatase activity
K1720_02865	COG0297	glycogen (starch) synthase activity
K1720_02865	COG0438	transferase activity, transferring glycosyl groups
K1720_02895	COG0673	inositol 2-dehydrogenase activity
K1720_02910	COG2046	Belongs to the sulfate adenylyltransferase family
K1720_02925	COG0529	Catalyzes the synthesis of activated sulfate
K1720_02930	COG0730	response to heat
K1720_03020	COG0438	transferase activity, transferring glycosyl groups
K1720_03045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K1720_03055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K1720_03110	COG0714	Associated with various cellular activities
K1720_03145	COG2442	InterPro IPR007367
K1720_03180	COG0647	UMP catabolic process
K1720_03190	COG0539	negative regulation of cytoplasmic translation
K1720_03215	COG2890	protein-(glutamine-N5) methyltransferase activity
K1720_03290	COG0519	Catalyzes the synthesis of GMP from XMP
K1720_03290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K1720_03300	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K1720_03305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K1720_03305	COG0519	Catalyzes the synthesis of GMP from XMP
K1720_03310	COG0516	GMP reductase activity
K1720_03310	COG0517	IMP dehydrogenase activity
K1720_03335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K1720_03340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K1720_03345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K1720_03355	COG0047	phosphoribosylformylglycinamidine synthase activity
K1720_03370	COG0151	Belongs to the GarS family
K1720_03375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K1720_03380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K1720_03385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K1720_03390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K1720_03395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K1720_03400	COG3383	formate dehydrogenase (NAD+) activity
K1720_03430	COG0668	transmembrane transport
K1720_03450	COG2264	protein methyltransferase activity
K1720_03475	COG0124	histidyl-tRNA synthetase
K1720_03495	COG1346	cytolysis
K1720_03500	COG1380	Effector of murein hydrolase LrgA
K1720_03530	COG1215	transferase activity, transferring glycosyl groups
K1720_03555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K1720_03565	COG0456	acetyltransferase
K1720_03575	COG0156	8-amino-7-oxononanoate synthase activity
K1720_03585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K1720_03590	COG2255	four-way junction helicase activity
K1720_03605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K1720_03615	COG1530	ribonuclease E activity
K1720_03620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K1720_03625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1720_03640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K1720_03705	COG0281	malic enzyme
K1720_03720	COG2151	metal-sulfur cluster biosynthetic enzyme
K1720_03725	COG1141	Ferredoxin
K1720_03740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_03740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_03755	COG0730	response to heat
K1720_03760	COG0730	response to heat
K1720_03765	COG1363	Peptidase, m42
K1720_03775	COG0123	including yeast histone deacetylase and acetoin utilization protein
K1720_03780	COG0123	including yeast histone deacetylase and acetoin utilization protein
K1720_03785	COG1131	(ABC) transporter
K1720_03810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K1720_03820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K1720_03825	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
K1720_03850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K1720_03855	COG0517	IMP dehydrogenase activity
K1720_03865	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
K1720_03880	COG1201	RNA secondary structure unwinding
K1720_03890	COG1505	serine-type exopeptidase activity
K1720_03910	COG1047	Peptidyl-prolyl cis-trans
K1720_03915	COG0215	cysteine-tRNA ligase activity
K1720_03920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1720_03930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K1720_03940	COG0803	Belongs to the bacterial solute-binding protein 9 family
K1720_03945	COG1079	Belongs to the binding-protein-dependent transport system permease family
K1720_03950	COG4603	Belongs to the binding-protein-dependent transport system permease family
K1720_03955	COG3845	ABC transporter
K1720_03960	COG1744	ABC transporter substrate-binding protein PnrA-like
K1720_03970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K1720_03985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1720_03995	COG0237	dephospho-CoA kinase activity
K1720_04025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1720_04050	COG0432	Pfam Uncharacterised protein family UPF0047
K1720_04055	COG1234	tRNA 3'-trailer cleavage
K1720_04065	COG2814	Major facilitator Superfamily
K1720_04080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1720_04080	COG1042	CoA-binding domain protein
K1720_04080	COG0045	succinate-CoA ligase (ADP-forming) activity
K1720_04100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K1720_04115	COG1131	(ABC) transporter
K1720_04125	COG0126	phosphoglycerate kinase activity
K1720_04150	COG3842	ATPase activity
K1720_04155	COG1178	ABC-type Fe3 transport system permease component
K1720_04205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K1720_04220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K1720_04220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K1720_04225	COG1830	Aldolase
K1720_04235	COG1966	Carbon starvation protein
K1720_04250	COG0003	Pfam Anion-transporting ATPase
K1720_04265	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
K1720_04265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K1720_04305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1720_04310	COG0438	transferase activity, transferring glycosyl groups
K1720_04320	COG3842	ATPase activity
K1720_04325	COG3833	ABC-type maltose transport systems, permease component
K1720_04350	COG1554	hydrolase, family 65, central catalytic
K1720_04355	COG0010	Belongs to the arginase family
K1720_04365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K1720_04375	COG3769	mannosylglycerate metabolic process
K1720_04390	COG1793	dna ligase
K1720_04390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K1720_04395	COG0509	glycine decarboxylation via glycine cleavage system
K1720_04410	COG0495	leucyl-tRNA aminoacylation
K1720_04445	COG0446	pyridine nucleotide-disulphide oxidoreductase
K1720_04465	COG1404	Belongs to the peptidase S8 family
K1720_04470	COG1473	amidohydrolase
K1720_04485	COG0574	Belongs to the PEP-utilizing enzyme family
K1720_04485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K1720_04490	COG0534	Mate efflux family protein
K1720_04495	COG0534	Mate efflux family protein
K1720_04510	COG2814	Major facilitator Superfamily
K1720_04530	COG2814	Major facilitator Superfamily
K1720_04545	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
K1720_04565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K1720_04575	COG0089	rRNA binding
K1720_04580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K1720_04585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K1720_04590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K1720_04595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K1720_04600	COG0255	Belongs to the universal ribosomal protein uL29 family
K1720_04615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K1720_04620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K1720_04625	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K1720_04635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K1720_04645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K1720_04650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K1720_04665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K1720_04670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K1720_04680	COG0200	Binds to the 23S rRNA
K1720_04705	COG1102	Psort location Cytoplasmic, score
K1720_04720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K1720_04725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K1720_04730	COG2813	Specifically methylates the guanine in position
K1720_04740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K1720_04745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K1720_04750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K1720_04770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K1720_04775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K1720_04795	COG0148	phosphopyruvate hydratase activity
K1720_04800	COG0052	Belongs to the universal ribosomal protein uS2 family
K1720_04825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K1720_04835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1720_04840	COG1653	transport
K1720_04845	COG1175	transmembrane transport
K1720_04850	COG0395	ABC-type sugar transport system, permease component
K1720_04855	COG0438	transferase activity, transferring glycosyl groups
K1720_04865	COG3842	ATPase activity
K1720_04885	COG4208	sulfate ABC transporter
K1720_04890	COG3842	ATPase activity
K1720_04895	COG4143	(ABC) transporter
K1720_04915	COG0434	BtpA family
K1720_04925	COG1458	PINc domain ribonuclease
K1720_04950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K1720_04965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K1720_04970	COG0081	regulation of translation
K1720_04985	COG0717	Belongs to the dCTP deaminase family
K1720_05025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K1720_05030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K1720_05050	COG0049	tRNA binding
K1720_05065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K1720_05105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1720_05110	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
K1720_05160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K1720_05175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K1720_05195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K1720_05250	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
K1720_05275	COG1418	mRNA catabolic process
K1720_05285	COG0017	Asparaginyl-tRNA synthetase
K1720_05300	COG0585	pseudouridine synthase activity
K1720_05310	COG0284	orotidine-5'-phosphate decarboxylase activity
K1720_05315	COG0167	dihydroorotate dehydrogenase activity
K1720_05325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K1720_05330	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
K1720_05335	COG0540	Belongs to the ATCase OTCase family
K1720_05340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K1720_05350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K1720_05355	COG1522	sequence-specific DNA binding
K1720_05370	COG0475	glutathione-regulated potassium exporter activity
K1720_05375	COG0475	glutathione-regulated potassium exporter activity
K1720_05390	COG0037	tRNA processing
K1720_05400	COG1449	Belongs to the glycosyl hydrolase 57 family
K1720_05435	COG0351	phosphomethylpyrimidine kinase
K1720_05450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
K1720_05460	COG2890	protein-(glutamine-N5) methyltransferase activity
K1720_05470	COG1058	Belongs to the CinA family
K1720_05470	COG1546	Belongs to the CinA family
K1720_05475	COG0469	pyruvate kinase activity
K1720_05525	COG2414	aldehyde ferredoxin oxidoreductase
K1720_05535	COG0463	Glycosyl transferase, family 2
K1720_05550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K1720_05555	COG1993	acr, cog1993
K1720_05575	COG0668	transmembrane transport
K1720_05580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K1720_05590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K1720_05615	COG1082	Xylose isomerase domain protein TIM barrel
K1720_05620	COG0616	signal peptide processing
K1720_05645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K1720_05645	COG1918	ferrous iron import across plasma membrane
K1720_05660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K1720_05670	COG0163	prenyltransferase activity
K1720_05675	COG1522	sequence-specific DNA binding
K1720_05685	COG0012	GTP binding
K1720_05710	COG0534	Mate efflux family protein
K1720_05715	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
K1720_05730	COG0071	Belongs to the small heat shock protein (HSP20) family
K1720_05735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1720_05745	COG0693	protein deglycase activity
K1720_05780	COG1042	CoA-binding domain protein
K1720_05780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K1720_05780	COG0045	succinate-CoA ligase (ADP-forming) activity
K1720_05785	COG1110	DNA topoisomerase II activity
K1720_05805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K1720_05810	COG0105	UTP biosynthetic process
K1720_05825	COG0312	modulator of DNA gyrase
K1720_05830	COG0312	modulator of DNA gyrase
K1720_05845	COG1794	racemase activity, acting on amino acids and derivatives
K1720_05850	COG0598	Magnesium transport protein CorA
K1720_05870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K1720_05875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1720_05925	COG0243	molybdopterin cofactor binding
K1720_05940	COG0656	L-ascorbic acid biosynthetic process
K1720_05965	COG1185	polyribonucleotide nucleotidyltransferase activity
K1720_05985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K1720_05990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K1720_05995	COG1085	galactose-1-phosphate uridylyltransferase
K1720_06000	COG2723	6-phospho-beta-galactosidase activity
K1720_06015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K1720_06020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K1720_06070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K1720_06080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K1720_06110	COG0252	asparaginase activity
K1720_06115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K1720_06135	COG2894	cell division
K1720_06145	COG1063	alcohol dehydrogenase
K1720_06155	COG0072	phenylalanine-tRNA ligase activity
K1720_06160	COG0101	tRNA pseudouridine synthase activity
K1720_06165	COG0556	nucleotide-excision repair
K1720_06175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K1720_06185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1720_06190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K1720_06190	COG0140	phosphoribosyl-ATP diphosphatase activity
K1720_06195	COG0107	imidazoleglycerol-phosphate synthase activity
K1720_06200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K1720_06205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K1720_06210	COG0131	Imidazoleglycerol-phosphate dehydratase
K1720_06220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K1720_06245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K1720_06255	COG1011	Hydrolase
K1720_06270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K1720_06275	COG0733	neurotransmitter:sodium symporter activity
K1720_06295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K1720_06295	COG2022	thiamine diphosphate biosynthetic process
K1720_06370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K1720_06390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K1720_06440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K1720_06445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
K1720_06455	COG0589	response to stress
K1720_06475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K1720_06495	COG1121	(ABC) transporter
K1720_06500	COG1205	dead DEAH box helicase
K1720_06500	COG1111	helicase
K1720_06515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K1720_06530	COG0330	HflC and HflK could
K1720_06535	COG2894	cell division
K1720_06545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K1720_06560	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
K1720_06570	COG2362	D-Aminopeptidase
K1720_06585	COG0513	Belongs to the DEAD box helicase family
K1720_06590	COG1342	Belongs to the UPF0251 family
K1720_06610	COG0489	protein tyrosine kinase activity
K1720_06635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K1720_06640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K1720_06640	COG0731	radical SAM domain protein
K1720_06660	COG2226	methyltransferase
K1720_06700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K1720_06710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K1720_06715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K1720_06765	COG1196	nuclear chromosome segregation
K1720_06770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K1720_06785	COG0483	inositol monophosphate 1-phosphatase activity
K1720_06795	COG1454	alcohol dehydrogenase
K1720_06805	COG1984	allophanate hydrolase subunit 2
K1720_06810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K1720_06815	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K1720_06845	COG0864	Transcriptional regulator
K1720_06870	COG1192	Involved in chromosome partitioning
K1720_06940	COG1983	PspC domain protein
K1720_06945	COG0588	phosphoglycerate mutase activity
K1720_06980	COG0709	Synthesizes selenophosphate from selenide and ATP
K1720_06985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K1720_06995	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
K1720_07000	COG0579	oxidoreductase
K1720_07010	COG0277	FAD linked oxidase domain protein
K1720_07015	COG0436	Aminotransferase
K1720_07020	COG2192	nodulation
K1720_07120	COG0148	phosphopyruvate hydratase activity
K1720_07135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K1720_07140	COG0183	Belongs to the thiolase family
K1720_07185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1720_07185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1720_07190	COG2140	Oxalate decarboxylase
K1720_07195	COG1994	Peptidase M50
K1720_07210	COG1473	amidohydrolase
K1720_07215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K1720_07220	COG1522	sequence-specific DNA binding
K1720_07235	COG1234	tRNA 3'-trailer cleavage
K1720_07255	COG0746	molybdenum cofactor guanylyltransferase activity
K1720_07260	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
K1720_07275	COG1120	ATPase activity
K1720_07280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1720_07310	COG0563	adenylate kinase activity
K1720_07330	COG1863	multisubunit Na H antiporter MnhE subunit
K1720_07335	COG2212	antiporter activity
K1720_07340	COG1320	monovalent cation:proton antiporter activity
K1720_07365	COG0651	ATP synthesis coupled electron transport
K1720_07385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K1720_07390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K1720_07405	COG0438	transferase activity, transferring glycosyl groups
K1720_07435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K1720_07440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1720_07450	COG1476	TRANSCRIPTIONal
K1720_07470	COG1444	tRNA N-acetyltransferase activity
K1720_07475	COG0823	Involved in the tonB-independent uptake of proteins
K1720_07475	COG1506	peptidase
K1720_07475	COG4946	Tricorn protease homolog
K1720_07485	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
K1720_07500	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K1720_07510	COG1573	uracil-dna glycosylase
K1720_07515	COG1757	Na H antiporter
K1720_07540	COG1793	dna ligase
K1720_07615	COG0546	phosphoglycolate phosphatase activity
K1720_07625	COG0436	Aminotransferase
K1720_07635	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K1720_07640	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K1720_07645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1720_07655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K1720_07670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K1720_07680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K1720_07690	COG0235	Class ii aldolase
K1720_07700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
K1720_07710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1720_07730	COG0011	TIGRFAM Protein of
K1720_07735	COG2078	PFAM AMMECR1 domain protein
K1720_07745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K1720_07745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K1720_07770	COG4608	Belongs to the ABC transporter superfamily
K1720_07775	COG0444	Belongs to the ABC transporter superfamily
K1720_07780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K1720_07785	COG0601	transmembrane transport
K1720_07790	COG0747	negative chemotaxis
K1720_07815	COG0543	2 iron, 2 sulfur cluster binding
K1720_07820	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
K1720_07820	COG0493	'glutamate synthase
K1720_07825	COG0312	modulator of DNA gyrase
K1720_07835	COG0312	modulator of DNA gyrase
K1720_07840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K1720_07905	COG0579	oxidoreductase
K1720_07915	COG0584	glycerophosphoryl diester phosphodiesterase
K1720_07930	COG1192	Involved in chromosome partitioning
K1720_07935	COG2211	Major facilitator Superfamily
K1720_07945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K1720_07950	COG0384	phenazine biosynthesis protein PhzF
K1720_07965	COG1872	DUF167
K1720_07980	COG0423	glycine-tRNA ligase activity
K1720_08005	COG1899	peptidyl-lysine modification to peptidyl-hypusine
K1720_08010	COG0303	'Molybdopterin
K1720_08020	COG2226	methyltransferase
K1720_08025	COG0525	valine-tRNA ligase activity
K1720_08045	COG0501	Belongs to the peptidase M48B family
K1720_08050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K1720_08060	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
K1720_08070	COG1515	deoxyribonuclease V activity
K1720_08105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K1720_08130	COG0402	S-adenosylhomocysteine deaminase activity
K1720_08135	COG0017	Asparaginyl-tRNA synthetase
K1720_08150	COG0489	protein tyrosine kinase activity
K1720_08160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1720_08165	COG1115	amino acid carrier protein
K1720_08170	COG1213	nucleotidyl transferase
K1720_08170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K1720_08175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K1720_08190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K1720_08195	COG0442	prolyl-tRNA aminoacylation
K1720_08205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K1720_08210	COG1392	Phosphate transport regulator
K1720_08215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K1720_08240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K1720_08250	COG0006	proline dipeptidase activity
K1720_08255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K1720_08295	COG0306	phosphate transporter
K1720_08320	COG4946	Tricorn protease homolog
K1720_08320	COG1506	peptidase
K1720_08320	COG0823	Involved in the tonB-independent uptake of proteins
K1720_08340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K1720_08380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K1720_08385	COG1373	ATPase (AAA superfamily
K1720_08395	COG0010	Belongs to the arginase family
K1720_08400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_08400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_08430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K1720_08450	COG2264	protein methyltransferase activity
K1720_08485	COG2226	methyltransferase
K1720_08525	COG4912	Dna alkylation repair
K1720_08540	COG1056	cytidyltransferase-related domain
K1720_08540	COG1051	belongs to the nudix hydrolase family
K1720_08560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K1720_08590	COG0560	Phosphoserine phosphatase
K1720_08595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K1720_08635	COG1469	GTP cyclohydrolase I activity
K1720_08660	COG2205	protein histidine kinase activity
K1720_08665	COG1185	polyribonucleotide nucleotidyltransferase activity
K1720_08685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K1720_08690	COG0733	neurotransmitter:sodium symporter activity
K1720_08700	COG0347	Belongs to the P(II) protein family
K1720_08705	COG1543	Belongs to the glycosyl hydrolase 57 family
K1720_08710	COG1293	RNA-binding protein homologous to eukaryotic snRNP
K1720_08750	COG0493	'glutamate synthase
K1720_08750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
K1720_08790	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K1720_08800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K1720_08830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K1720_08845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K1720_08850	COG0492	ferredoxin-NADP+ reductase activity
K1720_08870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K1720_08885	COG1628	Protein of unknown function DUF99
K1720_08890	COG1324	tolerance protein
K1720_08895	COG1254	Belongs to the acylphosphatase family
K1720_08940	COG0750	zinc metalloprotease
K1720_08945	COG0095	Lipoate-protein ligase
K1720_08950	COG0681	Belongs to the peptidase S26 family
K1720_08970	COG2226	methyltransferase
K1720_09015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K1720_09020	COG1078	dGTPase activity
K1720_09040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K1720_09055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K1720_09055	COG0517	IMP dehydrogenase activity
K1720_09080	COG2814	Major facilitator Superfamily
K1720_09100	COG1028	Short-chain dehydrogenase reductase Sdr
K1720_09130	COG0667	Aldo Keto reductase
K1720_09170	COG1489	DNA binding
K1720_09180	COG4974	Belongs to the 'phage' integrase family
K1720_09190	COG3473	Maleate cis-trans isomerase
K1720_09210	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K1720_09215	COG1355	regulation of microtubule-based process
K1720_09230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K1720_09235	COG1304	FMN binding
K1720_09240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K1720_09270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K1720_09305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K1720_09310	COG1522	sequence-specific DNA binding
K1720_09370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K1720_09375	COG1122	ATPase activity
K1720_09385	COG1268	BioY protein
K1720_09410	COG1694	Mazg nucleotide pyrophosphohydrolase
K1720_09415	COG1522	sequence-specific DNA binding
K1720_09435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K1720_09435	COG0301	tRNA thio-modification
K1720_09455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K1720_09465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K1720_09470	COG0463	Glycosyl transferase, family 2
K1720_09480	COG2131	deaminase
K1720_09485	COG0501	Belongs to the peptidase M48B family
K1720_09505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K1720_09510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K1720_09520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1720_09525	COG0650	Formate hydrogenlyase subunit 4
K1720_09535	COG0649	NAD binding
K1720_09535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K1720_09540	COG3260	NADH ubiquinone oxidoreductase 20
K1720_09550	COG0651	ATP synthesis coupled electron transport
K1720_09575	COG1320	monovalent cation:proton antiporter activity
K1720_09580	COG2212	antiporter activity
K1720_09595	COG0650	Formate hydrogenlyase subunit 4
K1720_09605	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
K1720_09605	COG3261	NADH dehydrogenase
K1720_09610	COG3260	NADH ubiquinone oxidoreductase 20
K1720_09620	COG0651	ATP synthesis coupled electron transport
K1720_09625	COG1006	Multisubunit Na H antiporter MnhC subunit
K1720_09645	COG1320	monovalent cation:proton antiporter activity
K1720_09650	COG2212	antiporter activity
K1720_09655	COG1863	multisubunit Na H antiporter MnhE subunit
K1720_09665	COG1968	undecaprenyl-diphosphatase activity
K1720_09670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K1720_09680	COG0517	IMP dehydrogenase activity
K1720_09680	COG0516	GMP reductase activity
K1720_09695	COG0310	cobalt ion transport
K1720_09710	COG1122	ATPase activity
K1720_09715	COG0058	SHG alpha-glucan phosphorylase activity
K1720_09720	COG0528	UMP kinase activity
K1720_09730	COG0733	neurotransmitter:sodium symporter activity
K1720_09735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K1720_09740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K1720_09750	COG2119	membrane
K1720_09755	COG0436	Aminotransferase
K1720_09770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K1720_09775	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K1720_09775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K1720_09795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_09795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K1720_09810	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K1720_09845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K1720_09850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K1720_09855	COG1185	polyribonucleotide nucleotidyltransferase activity
K1720_09865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
K1720_09900	COG0504	CTP synthase activity
K1720_09920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K1720_09935	COG0312	modulator of DNA gyrase
K1720_09940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K1720_09955	COG1131	(ABC) transporter
K1720_09980	COG0489	protein tyrosine kinase activity
K1720_09985	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1720_09990	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1720_10000	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1720_10005	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1720_10010	COG1144	Oxidoreductase
K1720_10020	COG0306	phosphate transporter
K1720_10030	COG1131	(ABC) transporter
K1720_10035	COG1476	TRANSCRIPTIONal
K1720_10055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K1720_10070	COG0303	'Molybdopterin
K1720_10075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K1720_10105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1720_10105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K1720_10110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K1720_10115	COG0424	maF-like protein
K1720_10120	COG4956	integral membrane protein (PIN domain superfamily)
K1720_10125	COG2894	cell division
K1720_10135	COG0367	asparagine synthase
K1720_10145	COG0297	glycogen (starch) synthase activity
K1720_10150	COG0009	L-threonylcarbamoyladenylate synthase
K1720_10250	COG0251	oxidation-reduction process
K1720_10260	COG0733	neurotransmitter:sodium symporter activity
K1720_10265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K1720_10275	COG1522	sequence-specific DNA binding
K1720_10285	COG1757	Na H antiporter
K1720_10300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K1720_10320	COG0477	Major facilitator Superfamily
K1720_10325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K1720_10340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K1720_10350	COG1522	sequence-specific DNA binding
K1720_10380	COG0409	Hydrogenase expression formation protein
K1720_10385	COG0298	carbon dioxide binding
K1720_10415	COG1131	(ABC) transporter
K1720_10430	COG0084	hydrolase, TatD family'
K1720_10445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K1720_10450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K1720_10460	COG1201	RNA secondary structure unwinding
K1720_10470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K1720_10490	COG1120	ATPase activity
K1720_10495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K1720_10505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K1720_10520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K1720_10525	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1720_10530	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1720_10530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K1720_10540	COG1013	pyruvate-flavodoxin oxidoreductase activity
K1720_10545	COG0674	pyruvate-flavodoxin oxidoreductase activity
K1720_10545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K1720_10565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K1720_10585	COG0460	homoserine dehydrogenase