locus-tag	class	description
A3L12_00005	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3L12_00010	ENOG4105E5K	Alpha-amylase
A3L12_00030	ENOG4105CD5	CoA-binding domain protein
A3L12_00035	ENOG4105C31	Tryptophanyl-tRNA synthetase
A3L12_00045	ENOG4105ERH	Fumarylacetoacetate hydrolase
A3L12_00055	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A3L12_00060	ENOG4105E2Z	phosphate ABC transporter (Permease
A3L12_00075	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
A3L12_00080	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3L12_00085	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L12_00120	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A3L12_00140	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L12_00160	ENOG4105CTD	carboxy-peptidase
A3L12_00175	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3L12_00185	ENOG4107R56	PP-loop domain protein
A3L12_00190	ENOG4105C0H	protease
A3L12_00195	ENOG4105CVK	Glutamate decarboxylase
A3L12_00200	ENOG4107RWR	Sodium hydrogen exchanger
A3L12_00225	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A3L12_00230	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L12_00245	ENOG4105DZ0	fad dependent oxidoreductase
A3L12_00255	ENOG4107RWR	Sodium hydrogen exchanger
A3L12_00260	ENOG4107RWR	Sodium hydrogen exchanger
A3L12_00270	ENOG4105CUT	histidyl-tRNA synthetase
A3L12_00280	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L12_00305	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L12_00335	ENOG4105NBF	ammecr1 domain protein
A3L12_00340	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L12_00365	ENOG4107STW	synthase
A3L12_00375	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L12_00395	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L12_00405	ENOG4108RWI	nicotinamidase
A3L12_00455	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L12_00460	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L12_00465	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A3L12_00490	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L12_00495	ENOG4105D9Q	decarboxylase (Beta subunit)
A3L12_00500	ENOG4107QSA	Oxaloacetate decarboxylase
A3L12_00510	ENOG4105D8K	carboxyl transferase
A3L12_00545	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A3L12_00570	ENOG4105C5R	Aminotransferase
A3L12_00590	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3L12_00600	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3L12_00605	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L12_00610	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3L12_00620	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3L12_00625	ENOG41082SA	50s ribosomal protein l29
A3L12_00630	ENOG4108ZJT	translation initiation factor, Sui1
A3L12_00640	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3L12_00645	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3L12_00650	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3L12_00660	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L12_00670	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3L12_00695	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3L12_00700	ENOG4105VPB	50S ribosomal protein L30
A3L12_00705	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3L12_00730	ENOG4107RB4	Cytidine monophosphate kinase
A3L12_00740	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3L12_00745	ENOG4107Y49	methyltransferase
A3L12_00755	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L12_00760	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3L12_00765	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3L12_00785	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3L12_00790	ENOG4108UJD	30S ribosomal protein S9
A3L12_00810	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L12_00815	ENOG4105CE9	30S ribosomal protein S2
A3L12_00855	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L12_00870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L12_00885	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A3L12_00895	ENOG4108YXU	transcriptional regulator AsnC family
A3L12_00915	ENOG4108I5U	Uridine phosphorylase
A3L12_00920	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A3L12_00935	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
A3L12_00945	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A3L12_00950	ENOG4105CN5	Metallo-Beta-Lactamase
A3L12_00955	ENOG4105EAH	synthase
A3L12_00965	ENOG4105C8T	Leucyl-tRNA synthetase
A3L12_00990	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A3L12_01000	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L12_01015	ENOG4107RFW	hydrolase family 57
A3L12_01020	ENOG4108YZA	Nitrogen regulatory protein pii
A3L12_01030	ENOG4105C8J	)-transporter
A3L12_01035	ENOG4105D82	Glutamate dehydrogenase
A3L12_01055	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L12_01060	ENOG4105CY0	Metallo-Beta-Lactamase
A3L12_01075	ENOG4105E66	phosphoriboisomerase A
A3L12_01085	ENOG4105UQX	Mate efflux family protein
A3L12_01125	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L12_01145	ENOG4107G87	m6 family metalloprotease domain protein
A3L12_01175	ENOG4108JQ7	(ABC) transporter
A3L12_01180	ENOG4105C3U	ABC transporter
A3L12_01185	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L12_01190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L12_01195	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L12_01220	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L12_01240	ENOG4105CHR	reductase
A3L12_01250	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L12_01255	ENOG4105VG1	fes assembly suf system protein
A3L12_01265	ENOG4108JVH	Protein of unknown function DUF43
A3L12_01275	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L12_01280	ENOG4105TMB	Formate nitrite transporter
A3L12_01285	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A3L12_01290	ENOG4108393	oxidoreductase Fe-S subunit
A3L12_01295	ENOG4105WGB	oxidoreductase, delta subunit
A3L12_01300	ENOG4105BZ8	glutamate synthase
A3L12_01305	ENOG4108RC0	Electron transport protein
A3L12_01315	ENOG4105CJ1	ABC, transporter
A3L12_01335	ENOG4105DZR	Type I site-specific deoxyribonuclease
A3L12_01340	ENOG4105EKX	Restriction modification system DNA (Specificity
A3L12_01350	ENOG4105CVR	type I restriction-modification system
A3L12_01365	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L12_01370	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3L12_01385	ENOG4108R3D	Electron transport complex
A3L12_01390	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
A3L12_01395	ENOG41080HI	glycine oxidase
A3L12_01420	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
A3L12_01425	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A3L12_01430	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L12_01435	ENOG4108I5D	sulfate abc transporter
A3L12_01440	ENOG41066FR	extracellular solute-binding protein
A3L12_01450	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L12_01475	ENOG4105K4P	CoA-binding domain protein
A3L12_01480	ENOG4105D1Z	hydroxypyruvate reductase
A3L12_01490	ENOG4108IJ9	(ABC) transporter
A3L12_01520	ENOG4106J7S	Glycosyl transferase, family 2
A3L12_01525	ENOG4105D7K	pfkb domain protein
A3L12_01560	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A3L12_01585	ENOG4105CX6	glutaminyL-tRNA synthetase
A3L12_01595	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A3L12_01605	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3L12_01615	ENOG4105CT4	transporter
A3L12_01625	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L12_01630	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L12_01665	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L12_01670	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L12_01675	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L12_01680	ENOG4105CJ1	ABC, transporter
A3L12_01710	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L12_01720	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L12_01740	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3L12_01745	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L12_01770	ENOG4105CHM	Aminotransferase
A3L12_01785	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L12_01810	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A3L12_01830	ENOG4108Y83	glucose-6-phosphate isomerase
A3L12_01835	ENOG4108Z4T	Peptidase M50
A3L12_01855	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L12_01870	ENOG4105D1F	ATP-binding protein
A3L12_01880	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
A3L12_01885	ENOG4105CQS	hydrogenase expression formation protein HypD
A3L12_01895	ENOG4105C45	hydrogenase expression formation protein (HypE)
A3L12_01910	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L12_01955	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L12_01970	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A3L12_01975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3L12_02000	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L12_02015	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3L12_02020	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3L12_02040	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L12_02080	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3L12_02095	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3L12_02105	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L12_02110	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L12_02125	ENOG4105CHM	Aminotransferase
A3L12_02160	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L12_02165	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A3L12_02180	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L12_02200	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A3L12_02250	ENOG4105CHU	acetyl-coa acetyltransferase
A3L12_02255	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A3L12_02265	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A3L12_02275	ENOG4107XMU	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L12_02280	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L12_02285	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L12_02290	ENOG4108Z86	Glutamine amidotransferase
A3L12_02300	ENOG4108UKZ	OsmC family
A3L12_02305	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L12_02325	ENOG4108Z0Z	intracellular protease Pfpi family
A3L12_02350	ENOG4105CK7	Sodium proline symporter
A3L12_02365	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A3L12_02370	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3L12_02380	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A3L12_02410	ENOG4105EHU	Circadian clock protein KaiC
A3L12_02420	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A3L12_02425	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L12_02435	ENOG4105C1A	potassium transporter peripheral membrane
A3L12_02455	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L12_02470	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A3L12_02485	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L12_02500	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L12_02505	ENOG4105CD3	dihydroorotase
A3L12_02520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L12_02525	ENOG4105C3U	ABC transporter
A3L12_02530	ENOG4108JQ7	(ABC) transporter
A3L12_02540	ENOG4105C4K	Nad synthetase
A3L12_02550	ENOG4105C5F	glutamine synthetase
A3L12_02585	ENOG4105EHU	Circadian clock protein KaiC
A3L12_02595	ENOG4105DR4	Methyltransferase
A3L12_02600	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L12_02605	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L12_02610	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L12_02615	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L12_02635	ENOG4105EG2	ABC transporter, permease
A3L12_02645	ENOG4107FKK	extracellular solute-binding protein family 1
A3L12_02655	ENOG4108NGU	Transcriptional regulator
A3L12_02660	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L12_02675	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3L12_02680	ENOG4105D6J	arsenicaL-resistance protein
A3L12_02705	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L12_02735	ENOG4105M7V	2'-5' rna ligase
A3L12_02745	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
A3L12_02770	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L12_02770	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L12_02820	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L12_02865	ENOG4107TSN	permease
A3L12_02870	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A3L12_02895	ENOG4107RIQ	Sulfate adenylate transferase
A3L12_02940	ENOG4105J5G	Transferase hexapeptide repeat containing protein
A3L12_02950	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L12_02955	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3L12_02960	ENOG4107RA4	Glycosyl transferase (Group 1
A3L12_02965	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L12_02975	ENOG4105D7V	transposase
A3L12_02995	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L12_03035	ENOG4108IYU	L-aspartate oxidase
A3L12_03040	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A3L12_03045	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A3L12_03050	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A3L12_03055	ENOG4108R6K	riboflavin synthase, subunit alpha
A3L12_03060	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A3L12_03065	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A3L12_03080	ENOG4105C8V	SAICAR synthetase
A3L12_03085	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A3L12_03095	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
A3L12_03100	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A3L12_03105	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A3L12_03115	ENOG4105C8V	SAICAR synthetase
A3L12_03125	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A3L12_03130	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A3L12_03135	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A3L12_03140	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A3L12_03155	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A3L12_03160	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A3L12_03170	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L12_03175	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L12_03180	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L12_03245	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A3L12_03270	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A3L12_03275	ENOG4105F0N	pyrophosphate phospho-hydrolase
A3L12_03330	ENOG4105EHU	Circadian clock protein KaiC
A3L12_03340	ENOG4105IIU	Aminopeptidase
A3L12_03360	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A3L12_03370	ENOG4105K8R	UPF0145 protein
A3L12_03390	ENOG4105EHU	Circadian clock protein KaiC
A3L12_03395	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L12_03400	ENOG4105D64	Mechanosensitive ion channel
A3L12_03440	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A3L12_03460	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3L12_03465	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3L12_03475	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A3L12_03515	ENOG4105D7N	magnesium and cobalt transport protein CorA
A3L12_03530	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A3L12_03535	ENOG4105EAC	phosphoserine phosphatase
A3L12_03590	ENOG4105BZ1	(ABC) transporter
A3L12_03595	ENOG4105BZ1	(ABC) transporter
A3L12_03615	ENOG4105CJ1	ABC, transporter
A3L12_03635	ENOG4105D0M	Protease HtpX homolog
A3L12_03640	ENOG4108UK2	deaminase
A3L12_03650	ENOG4105CKK	Glycosyl transferase, family 2
A3L12_03655	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A3L12_03665	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L12_03690	ENOG4105D44	asparaginase
A3L12_03705	ENOG4105DK7	lysyl-tRNA synthetase
A3L12_03730	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3L12_03760	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L12_03770	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L12_03775	ENOG4105C6E	dna polymerase iii
A3L12_03780	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A3L12_03790	ENOG4108J2R	molybdopterin oxidoreductase
A3L12_03830	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A3L12_03835	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L12_03865	ENOG4107ZCS	Phosphomethylpyrimidine kinase
A3L12_03870	ENOG4105CXT	aspartate transcarbamylase
A3L12_03875	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A3L12_03890	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A3L12_03900	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L12_03920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L12_03945	ENOG4107R3E	Citrate transporter
A3L12_03960	ENOG4105CWC	Acetylornithine deacetylase
A3L12_03970	ENOG4108JQ1	Dehydrogenase
A3L12_03980	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A3L12_04005	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3L12_04010	ENOG4107QXV	Phosphate transporter
A3L12_04025	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L12_04030	ENOG4105DDK	oxidoreductase, beta subunit
A3L12_04040	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L12_04045	ENOG4105DDK	oxidoreductase, beta subunit
A3L12_04050	ENOG4105D1F	ATP-binding protein
A3L12_04075	ENOG4108RVA	ribokinase
A3L12_04085	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A3L12_04090	ENOG4108UUC	Protein of unknown function DUF99
A3L12_04095	ENOG4107YZX	Universal stress protein
A3L12_04115	ENOG4107NFR	Fructose-1,6-bisphosphatase
A3L12_04120	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A3L12_04130	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L12_04145	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A3L12_04170	ENOG4105CIG	ABC transporter
A3L12_04215	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A3L12_04225	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A3L12_04230	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L12_04240	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A3L12_04250	ENOG4107QIM	DNA ligase
A3L12_04265	ENOG4105CJ1	ABC, transporter
A3L12_04270	ENOG4107S6Z	Na H antiporter
A3L12_04305	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L12_04310	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L12_04315	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L12_04320	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L12_04330	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L12_04355	ENOG4107W7X	Aldolase
A3L12_04365	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A3L12_04380	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A3L12_04385	ENOG4105VFR	signal peptidase
A3L12_04410	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L12_04450	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L12_04455	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L12_04460	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L12_04465	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L12_04470	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L12_04495	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L12_04505	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L12_04510	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L12_04515	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L12_04520	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L12_04525	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L12_04550	ENOG4105C3M	thioredoxin reductase
A3L12_04555	ENOG4108JPW	Aminotransferase
A3L12_04570	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A3L12_04575	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L12_04585	ENOG4108VVK	transcriptional Regulator, AsnC
A3L12_04590	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A3L12_04610	ENOG4108ZAF	Molybdopterin
A3L12_04620	ENOG4105D06	uba thif-type nad fad binding protein
A3L12_04640	ENOG4105E7W	lamb ycsf family protein
A3L12_04645	ENOG4105P4J	Allophanate hydrolase, subunit 1
A3L12_04695	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L12_04700	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L12_04705	ENOG4105CD5	CoA-binding domain protein
A3L12_04740	ENOG4105C9M	aspartyl-trna synthetase
A3L12_04765	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
A3L12_04780	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A3L12_04785	ENOG4105DM4	PTS System
A3L12_04790	ENOG4105DM4	PTS System
A3L12_04795	ENOG4105DE4	1-phosphofructokinase
A3L12_04835	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L12_04850	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L12_04855	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A3L12_04865	ENOG4108K7V	UPF0284 protein
A3L12_04870	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A3L12_04875	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L12_04880	ENOG4105KST	dependent repressor
A3L12_04895	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A3L12_04910	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L12_04915	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A3L12_04920	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A3L12_04925	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3L12_04935	ENOG4108JPW	Aminotransferase
A3L12_04940	ENOG4108TVJ	Nitroreductase
A3L12_04955	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L12_04970	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L12_04990	ENOG4105CG9	aspartate racemase
A3L12_04995	ENOG4105C3G	gtp-binding protein
A3L12_05010	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A3L12_05030	ENOG4105CE1	Ferrous iron transport protein b
A3L12_05055	ENOG4105DC7	peptidase M24
A3L12_05065	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L12_05075	ENOG4105UQX	Mate efflux family protein
A3L12_05095	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A3L12_05105	ENOG4105VZ9	UPF0235 protein
A3L12_05120	ENOG4108I62	cina-like protein
A3L12_05125	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L12_05135	ENOG4108WBT	adenosyltransferase
A3L12_05165	ENOG4105DER	m42 family
A3L12_05190	ENOG4105CND	Glycosyl transferase, family 2
A3L12_05195	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A3L12_05200	ENOG4107QRT	dEAD DEAH box helicase
A3L12_05205	ENOG4105EHU	Circadian clock protein KaiC
A3L12_05215	ENOG4105DWF	phosphomethylpyrimidine kinase
A3L12_05220	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A3L12_05230	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A3L12_05235	ENOG4105C8N	cysteinyl-tRNA synthetase
A3L12_05240	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3L12_05260	ENOG4105UIB	(ABC) transporter
A3L12_05265	ENOG4108JQ9	ABC transporter
A3L12_05270	ENOG4105DIH	basic membrane
A3L12_05295	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A3L12_05300	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A3L12_05315	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L12_05320	ENOG4105DQU	oxidoreductase, subunit beta
A3L12_05330	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L12_05335	ENOG4105DQU	oxidoreductase, subunit beta
A3L12_05350	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A3L12_05370	ENOG4105HF0	Membrane
A3L12_05380	ENOG4105C5I	Dehydrogenase
A3L12_05385	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L12_05395	ENOG4105CHM	Aminotransferase
A3L12_05405	ENOG4107RB4	Cytidine monophosphate kinase
A3L12_05415	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A3L12_05425	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A3L12_05465	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A3L12_05475	ENOG4107SHJ	sulfite reductase subunit b
A3L12_05495	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A3L12_05515	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A3L12_05520	ENOG4105F7P	transcriptional regulator AsnC family
A3L12_05530	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L12_05550	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3L12_05615	ENOG4105C75	arginyL-tRNA synthetase
A3L12_05635	ENOG4108IJ1	Dehydrogenase
A3L12_05640	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3L12_05645	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L12_05655	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L12_05665	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L12_05675	ENOG4105D65	subunit l
A3L12_05680	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L12_05685	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L12_05690	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L12_05695	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A3L12_05700	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L12_05705	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L12_05710	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L12_05745	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A3L12_05770	ENOG4108V1U	phospholipid-binding protein
A3L12_05785	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L12_05790	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L12_05835	ENOG4105BZR	domain protein
A3L12_05850	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L12_05855	ENOG4105CV8	reductase
A3L12_05860	ENOG4105E3H	phosphoglycerate mutase
A3L12_05870	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A3L12_05880	ENOG4105DBV	ornithine carbamoyltransferase
A3L12_05885	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L12_05915	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A3L12_05945	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A3L12_06000	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A3L12_06010	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3L12_06040	ENOG4105HDK	L-asparaginase
A3L12_06045	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3L12_06060	ENOG4105CPQ	Dehydrogenase
A3L12_06065	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3L12_06075	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3L12_06080	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3L12_06085	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L12_06145	ENOG4105C22	threonyL-tRNA synthetase
A3L12_06160	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L12_06165	ENOG4108Z0R	Transferase
A3L12_06180	ENOG4105CN9	Peptidase m42 family protein
A3L12_06195	ENOG4108JJB	ABC transporter
A3L12_06200	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A3L12_06205	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3L12_06215	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L12_06225	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L12_06235	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L12_06245	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3L12_06270	ENOG4105CH2	amidohydrolase
A3L12_06280	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A3L12_06295	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L12_06315	ENOG4107XGZ	Hydrolase
A3L12_06325	ENOG4108VA3	3-hexulose-6-phosphate synthase
A3L12_06350	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A3L12_06370	ENOG4105CD5	CoA-binding domain protein
A3L12_06395	ENOG4105DTT	CRISPR-associated helicase, cas3
A3L12_06405	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3L12_06445	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L12_06450	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L12_06460	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A3L12_06495	ENOG4107Y70	Heat shock protein
A3L12_06500	ENOG4107T0X	DNA ligase
A3L12_06575	ENOG4105CD5	CoA-binding domain protein
A3L12_06590	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L12_06600	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L12_06605	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3L12_06625	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L12_06630	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L12_06640	ENOG4105CAQ	asparagine synthetase
A3L12_06650	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L12_06655	ENOG4108Z03	MAF-like protein
A3L12_06670	ENOG4105D5P	Methylmalonyl-coA mutase
A3L12_06690	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3L12_06700	ENOG4105C1J	atp-dependent rna helicase
A3L12_06710	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A3L12_06725	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A3L12_06735	ENOG4107QMS	site-determining protein
A3L12_06740	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L12_06780	ENOG4107QW4	alcohol dehydrogenase
A3L12_06790	ENOG4105ECY	inositol monophosphatase
A3L12_06815	ENOG4105C1J	atp-dependent rna helicase
A3L12_06840	ENOG4105CN9	Peptidase m42 family protein
A3L12_06850	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A3L12_06860	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3L12_06895	ENOG4105CD5	CoA-binding domain protein
A3L12_06905	ENOG4105CSM	endonuclease III
A3L12_06930	ENOG4105BZA	Phosphoglycerate kinase
A3L12_06945	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L12_06950	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
A3L12_06970	ENOG4105EW9	transcriptional regulator AsnC family
A3L12_06975	ENOG4105C1J	atp-dependent rna helicase
A3L12_06995	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A3L12_07000	ENOG4108JJB	ABC transporter
A3L12_07005	ENOG4105VKD	bioY protein
A3L12_07015	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L12_07020	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A3L12_07040	ENOG4105DP9	ABC transporter
A3L12_07050	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L12_07090	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A3L12_07095	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A3L12_07105	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L12_07115	ENOG4105F8V	Hydrolase, tatD family
A3L12_07130	ENOG4107VMB	Beta-lactamase domain protein
A3L12_07135	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L12_07155	ENOG4107QRT	dEAD DEAH box helicase
A3L12_07170	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L12_07175	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A3L12_07195	ENOG4105C83	adenylosuccinate lyase
A3L12_07200	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A3L12_07220	ENOG4105VYW	UPF0251 protein
A3L12_07245	ENOG4105CHR	reductase
A3L12_07280	ENOG4107QMS	site-determining protein
A3L12_07285	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L12_07305	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A3L12_07310	ENOG4105E5G	Alpha beta hydrolase fold
A3L12_07315	ENOG4107QSA	Oxaloacetate decarboxylase
A3L12_07320	ENOG41061GT	Aldolase
A3L12_07325	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L12_07330	ENOG4105CK2	sodium dicarboxylate symporter
A3L12_07340	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L12_07360	ENOG4105C0D	helicase
A3L12_07450	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L12_07465	ENOG4105PGM	cation diffusion facilitator family transporter
A3L12_07505	ENOG4105EHG	Permease protein
A3L12_07510	ENOG4105DIK	(ABC) transporter
A3L12_07585	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
A3L12_07595	ENOG4105C3K	feS assembly ATPase SufC
A3L12_07600	ENOG4105DIW	FeS assembly protein SUFB
A3L12_07610	ENOG4105D3R	alkyl hydroperoxide reductase
A3L12_07645	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3L12_07665	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
A3L12_07675	ENOG4105DCI	Phosphohydrolase
A3L12_07695	ENOG4105E0R	Deoxyhypusine synthase
A3L12_07700	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A3L12_07705	ENOG4105D0M	Protease HtpX homolog
A3L12_07715	ENOG4108V5V	Serine Threonine protein kinase
A3L12_07720	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L12_07735	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L12_07745	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A3L12_07775	ENOG4108JJB	ABC transporter
A3L12_07840	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L12_07845	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L12_07860	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3L12_07865	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3L12_07870	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3L12_07875	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A3L12_07900	ENOG41065SU	Two-component system sensor kinase
A3L12_07925	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3L12_07930	ENOG4105DIK	(ABC) transporter
A3L12_07940	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3L12_07950	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L12_07960	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L12_07970	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A3L12_08000	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L12_08030	ENOG4105WMR	Protein CrcB homolog
A3L12_08035	ENOG4105KJJ	Uncharacterized ACR, COG1993
A3L12_08040	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3L12_08045	ENOG4105D64	Mechanosensitive ion channel
A3L12_08075	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A3L12_08100	ENOG4105CIG	ABC transporter
A3L12_08110	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L12_08140	ENOG4108F3G	Type I restriction-modification system, R subunit
A3L12_08145	ENOG4108F3G	Type I restriction-modification system, R subunit
A3L12_08150	ENOG4105D1H	recombination factor protein RarA
A3L12_08160	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)