A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 3 273 41.75 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 Gene3D G3DSA:1.10.443.10 90 280 3.4E-74 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 Gene3D G3DSA:1.10.150.130 2 89 4.1E-19 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 76 2.7E-7 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 SUPERFAMILY SSF56349 2 269 6.18E-61 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L12_06860 9a87217a186230bee2c38a15ee8a6562 280 Pfam PF00589 Phage integrase family 98 261 3.2E-50 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L12_04655 9370ff581aee4c9d0bdd854923b03d82 168 Hamap MF_01117 CDP-archaeol synthase [carS]. 11 168 28.411 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L12_04655 9370ff581aee4c9d0bdd854923b03d82 168 Pfam PF01864 CDP-archaeol synthase 4 168 1.6E-60 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 SMART SM00116 139 187 1.2E-9 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 SMART SM00116 75 123 0.75 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 SMART SM00116 217 265 6.9E-6 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Gene3D G3DSA:3.10.580.10 208 303 3.2E-13 T 23-10-2018 A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Gene3D G3DSA:3.10.580.10 127 207 7.1E-18 T 23-10-2018 A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 PIRSF PIRSF036983 2 390 8.9E-134 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Pfam PF00571 CBS domain 6 55 0.0033 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Pfam PF00571 CBS domain 132 183 1.6E-16 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Pfam PF00571 CBS domain 74 121 2.1E-5 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Pfam PF00571 CBS domain 211 261 4.5E-10 T 23-10-2018 IPR000644 CBS domain A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 Gene3D G3DSA:3.10.580.10 1 126 4.9E-18 T 23-10-2018 A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 SUPERFAMILY SSF54631 3 121 4.3E-18 T 23-10-2018 A3L12_06215 a77f8cd24fc351924a7c31587ada061f 391 SUPERFAMILY SSF54631 126 261 1.53E-33 T 23-10-2018 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.9E-93 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 SUPERFAMILY SSF54821 86 186 4.19E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.436 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 SMART SM00322 38 104 1.4E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 SUPERFAMILY SSF54814 7 93 6.54E-26 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 Gene3D G3DSA:3.30.1140.32 87 206 5.5E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 2.0E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 Pfam PF07650 KH domain 17 88 2.2E-14 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00620 7b9fa2f61ef93032f863dde5897803e4 206 Gene3D G3DSA:3.30.300.20 1 86 1.2E-28 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_03545 4a924bc3fc24844614429def6f7f3f07 112 SUPERFAMILY SSF88697 1 108 1.62E-31 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_03545 4a924bc3fc24844614429def6f7f3f07 112 PIRSF PIRSF016134 2 111 9.4E-43 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L12_03545 4a924bc3fc24844614429def6f7f3f07 112 Pfam PF04266 ASCH domain 7 107 9.1E-12 T 23-10-2018 IPR007374 ASCH domain A3L12_03545 4a924bc3fc24844614429def6f7f3f07 112 Gene3D G3DSA:2.30.130.30 1 112 5.6E-38 T 23-10-2018 A3L12_03545 4a924bc3fc24844614429def6f7f3f07 112 SMART SM01022 6 109 8.6E-9 T 23-10-2018 IPR007374 ASCH domain A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 1.1E-60 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 SMART SM01210 328 418 1.0E-19 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 SMART SM01209 102 296 9.6E-99 T 23-10-2018 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 SUPERFAMILY SSF56059 103 323 1.33E-47 T 23-10-2018 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 2.6E-22 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Gene3D G3DSA:3.90.600.10 329 418 1.7E-9 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 SUPERFAMILY SSF52440 1 102 5.04E-25 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 1.5E-147 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Gene3D G3DSA:3.40.50.20 2 94 1.2E-21 T 23-10-2018 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 37.011 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 SUPERFAMILY SSF51246 327 417 9.42E-17 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 4.1E-13 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Gene3D G3DSA:3.30.1490.20 122 187 1.0E-14 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_03140 3926cdcc9104f5cb07983d04d4c32834 437 Gene3D G3DSA:3.30.470.20 189 328 1.0E-47 T 23-10-2018 A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 PIRSF PIRSF006443 1 171 2.1E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 SMART SM00852 17 165 1.4E-30 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 Pfam PF00994 Probable molybdopterin binding domain 17 160 3.7E-37 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 SUPERFAMILY SSF53218 13 167 1.26E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 Gene3D G3DSA:3.40.980.10 12 170 2.4E-48 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_04855 7a57e5f952068856b445012f9cf6ac87 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 2.3E-36 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_05455 d2986a8826975756612e62012d347730 289 SUPERFAMILY SSF103481 48 145 1.96E-13 T 23-10-2018 A3L12_05455 d2986a8826975756612e62012d347730 289 Pfam PF00892 EamA-like transporter family 6 141 5.0E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_05455 d2986a8826975756612e62012d347730 289 Pfam PF00892 EamA-like transporter family 154 288 1.0E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_05455 d2986a8826975756612e62012d347730 289 SUPERFAMILY SSF103481 188 288 2.62E-10 T 23-10-2018 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 366 7.8E-105 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Gene3D G3DSA:3.40.50.620 177 374 1.0E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Pfam PF02926 THUMP domain 28 167 2.0E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 376 123.663 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Gene3D G3DSA:3.30.70.1510 1 83 4.3E-30 T 23-10-2018 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 SUPERFAMILY SSF143437 1 175 1.1E-47 T 23-10-2018 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Gene3D G3DSA:3.30.2300.10 84 165 1.9E-29 T 23-10-2018 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 369 1.4E-64 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 SUPERFAMILY SSF52402 177 336 3.75E-49 T 23-10-2018 A3L12_06880 d84f25731ceda05301f16461ca56baf5 376 SMART SM00981 73 167 1.2E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.681 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 SUPERFAMILY SSF53633 1 224 3.27E-50 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 Gene3D G3DSA:3.40.1160.10 1 225 1.1E-58 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 PIRSF PIRSF005650 1 225 4.4E-60 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 Pfam PF00696 Amino acid kinase family 1 202 2.2E-32 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L12_02370 625bbdda8ee9319bbf24081856f77147 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 9.9E-85 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 SUPERFAMILY SSF53335 14 266 2.43E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 Gene3D G3DSA:3.40.50.150 1 194 1.5E-61 T 23-10-2018 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 SMART SM00650 30 193 1.4E-76 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 263 1.5E-70 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 44.133 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 Gene3D G3DSA:1.10.8.100 195 272 7.0E-8 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A3L12_06010 4bdc81c1fa029655df247611ec7eedd5 284 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 224 3.9E-51 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A3L12_06690 557327e016a41e5903499a36ce13e365 1187 SUPERFAMILY SSF75553 484 675 2.35E-49 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:1.20.5.340 772 973 5.0E-6 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:1.20.5.340 373 490 2.4E-5 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:3.40.50.300 2 233 4.8E-60 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1160 5.8E-233 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 PIRSF PIRSF005719 1 1167 1.8E-275 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A3L12_06690 557327e016a41e5903499a36ce13e365 1187 SMART SM00968 520 631 1.3E-41 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:3.30.70.1620 580 657 4.4E-45 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1162 21.102 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 SUPERFAMILY SSF57997 299 509 1.44E-6 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 SUPERFAMILY SSF52540 1 1168 4.8E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:1.20.1060.20 515 659 4.4E-45 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1153 1.9E-80 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 629 4.0E-32 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 Gene3D G3DSA:3.40.50.300 1009 1180 8.6E-60 T 23-10-2018 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1160 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L12_06690 557327e016a41e5903499a36ce13e365 1187 SUPERFAMILY SSF57997 731 961 6.28E-5 T 23-10-2018 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Pfam PF02824 TGS domain 314 385 5.4E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 SUPERFAMILY SSF52540 83 322 5.41E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Gene3D G3DSA:3.40.50.300 70 203 6.2E-35 T 23-10-2018 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Pfam PF16897 C-terminal region of MMR_HSR1 domain 204 309 1.8E-18 T 23-10-2018 IPR031662 GTP binding protein, second domain A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 149 167 4.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 105 123 4.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 84 104 4.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 132 147 4.8E-29 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 82 189 2.2E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Gene3D G3DSA:3.10.20.30 311 387 5.3E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 SUPERFAMILY SSF81271 308 385 1.7E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Pfam PF01926 50S ribosome-binding GTPase 83 183 2.4E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_02335 b3f42479867f2c84d75d2cfe4a1e7d29 387 Gene3D G3DSA:3.40.50.300 204 310 2.3E-8 T 23-10-2018 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.0 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 Gene3D G3DSA:3.30.1370.30 1 69 1.2E-31 T 23-10-2018 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 SUPERFAMILY SSF56047 3 130 2.09E-39 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 Pfam PF00410 Ribosomal protein S8 5 130 8.5E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00670 34a65cbc6f1178f73830e57787586464 130 Gene3D G3DSA:3.30.1490.10 70 128 5.8E-27 T 23-10-2018 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.412 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 3.9E-110 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 1.1E-124 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 SUPERFAMILY SSF100950 12 349 3.56E-110 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 Gene3D G3DSA:3.40.50.10470 159 357 2.4E-58 T 23-10-2018 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 Pfam PF01008 Initiation factor 2 subunit family 55 343 3.7E-78 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L12_07170 c872ab7827cc5b25a6bd55add08692cf 357 Gene3D G3DSA:1.20.120.420 11 156 6.0E-45 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 SUPERFAMILY SSF55060 182 328 4.52E-36 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 Gene3D G3DSA:3.30.230.10 1 181 1.6E-49 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 PRINTS PR00959 Mevalonate kinase family signature 149 168 7.6E-29 T 23-10-2018 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 PRINTS PR00959 Mevalonate kinase family signature 7 31 7.6E-29 T 23-10-2018 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 PRINTS PR00959 Mevalonate kinase family signature 106 128 7.6E-29 T 23-10-2018 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 PRINTS PR00959 Mevalonate kinase family signature 282 299 7.6E-29 T 23-10-2018 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 Gene3D G3DSA:3.30.70.890 186 317 3.0E-40 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 Pfam PF08544 GHMP kinases C terminal 242 310 1.0E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 297 1.3E-83 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 Pfam PF00288 GHMP kinases N terminal domain 102 168 2.0E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 108 119 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 SUPERFAMILY SSF54211 3 179 7.36E-45 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_00925 8c23b47e12889bcc724f8e6c815569d0 333 Hamap MF_00217 Mevalonate kinase [mvk]. 3 326 58.534 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A3L12_06370 b90e09f7e34e7e82bad2251a888171a7 232 Pfam PF13549 ATP-grasp domain 16 231 1.6E-83 T 23-10-2018 A3L12_06370 b90e09f7e34e7e82bad2251a888171a7 232 Gene3D G3DSA:3.30.470.20 21 230 1.7E-90 T 23-10-2018 A3L12_06370 b90e09f7e34e7e82bad2251a888171a7 232 SUPERFAMILY SSF56059 23 232 3.01E-50 T 23-10-2018 A3L12_06370 b90e09f7e34e7e82bad2251a888171a7 232 Gene3D G3DSA:3.30.1490.20 39 116 1.7E-90 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 3 250 1.1E-93 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 PRINTS PR00419 Adrenodoxin reductase family signature 48 61 9.8E-8 T 23-10-2018 A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 PRINTS PR00419 Adrenodoxin reductase family signature 25 47 9.8E-8 T 23-10-2018 A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 Pfam PF01946 Thi4 family 7 231 2.8E-81 T 23-10-2018 A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 250 44.439 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 SUPERFAMILY SSF51905 4 242 3.66E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_03095 670d341b7e52a64220fdbd655f78a24a 251 Gene3D G3DSA:3.50.50.60 1 251 7.7E-101 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Gene3D G3DSA:2.60.120.380 558 655 5.5E-16 T 23-10-2018 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Gene3D G3DSA:2.60.120.380 439 539 5.4E-22 T 23-10-2018 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 573 640 2.5E-7 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A3L12_01275 9b621a866105210137b3074b12a0d97e 658 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 375 385 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L12_01275 9b621a866105210137b3074b12a0d97e 658 PIRSF PIRSF037907 1 658 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Pfam PF00082 Subtilase family 157 426 2.0E-68 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Gene3D G3DSA:3.40.50.200 131 438 3.7E-133 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 SUPERFAMILY SSF52743 141 436 1.31E-95 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L12_01275 9b621a866105210137b3074b12a0d97e 658 Gene3D G3DSA:3.30.70.80 39 130 4.2E-39 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A3L12_01275 9b621a866105210137b3074b12a0d97e 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 3.2E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_01275 9b621a866105210137b3074b12a0d97e 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 374 390 3.2E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_01275 9b621a866105210137b3074b12a0d97e 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 3.2E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_01275 9b621a866105210137b3074b12a0d97e 658 SUPERFAMILY SSF49785 446 522 4.85E-6 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A3L12_02955 610f4a9ff825bc6acdf420a18102a0a1 358 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 354 5.3E-120 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L12_02955 610f4a9ff825bc6acdf420a18102a0a1 358 Gene3D G3DSA:3.40.50.2000 183 341 1.8E-139 T 23-10-2018 A3L12_02955 610f4a9ff825bc6acdf420a18102a0a1 358 SUPERFAMILY SSF53756 1 355 8.79E-120 T 23-10-2018 A3L12_02955 610f4a9ff825bc6acdf420a18102a0a1 358 Gene3D G3DSA:3.40.50.2000 6 351 1.8E-139 T 23-10-2018 A3L12_02955 610f4a9ff825bc6acdf420a18102a0a1 358 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 354 1.1E-117 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 351 1.8E-41 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 SUPERFAMILY SSF52374 2 363 2.11E-65 T 23-10-2018 A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 Gene3D G3DSA:1.10.240.10 227 375 1.0E-53 T 23-10-2018 A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 Gene3D G3DSA:3.40.50.620 1 226 1.3E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.258 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L12_06965 9e228cae8ef72ab93659d6a478ac4f51 375 PIRSF PIRSF006588 1 375 1.4E-127 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 SUPERFAMILY SSF52210 138 297 1.7E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 SUPERFAMILY SSF51735 6 136 1.87E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 Pfam PF13380 CoA binding domain 12 141 6.9E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 6 454 8.0E-183 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 Gene3D G3DSA:3.40.50.261 137 298 1.3E-63 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 SUPERFAMILY SSF52210 301 457 9.03E-32 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 Gene3D G3DSA:3.40.50.720 3 136 5.6E-45 T 23-10-2018 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 158 295 1.4E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 Gene3D G3DSA:3.40.50.261 299 462 3.1E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06575 ea82589f8f4837c017fe02d6b0b7fbb8 464 SMART SM00881 8 107 2.1E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Pfam PF00391 PEP-utilising enzyme, mobile domain 231 297 8.8E-12 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 SUPERFAMILY SSF51621 334 608 1.15E-91 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PIRSF PIRSF000732 91 618 2.9E-140 T 23-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 568 580 4.8E-21 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 362 381 4.8E-21 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 532 547 4.8E-21 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 515 530 4.8E-21 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Gene3D G3DSA:3.50.30.10 99 307 6.2E-31 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 82 2.6E-25 T 23-10-2018 IPR000032 Phosphocarrier protein HPr-like A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 336 609 7.0E-95 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 515 533 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR00107 Phosphocarrier protein signature 39 54 6.3E-14 T 23-10-2018 IPR000032 Phosphocarrier protein HPr-like A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR00107 Phosphocarrier protein signature 54 71 6.3E-14 T 23-10-2018 IPR000032 Phosphocarrier protein HPr-like A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 PRINTS PR00107 Phosphocarrier protein signature 14 30 6.3E-14 T 23-10-2018 IPR000032 Phosphocarrier protein HPr-like A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Gene3D G3DSA:1.10.274.10 113 223 6.2E-31 T 23-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 SUPERFAMILY SSF47831 127 219 9.29E-7 T 23-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Pfam PF00381 PTS HPr component phosphorylation site 4 82 5.7E-23 T 23-10-2018 IPR000032 Phosphocarrier protein HPr-like A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Gene3D G3DSA:3.30.1340.10 2 83 1.2E-24 T 23-10-2018 IPR035895 HPr-like superfamily A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 SUPERFAMILY SSF55594 4 85 5.76E-22 T 23-10-2018 IPR035895 HPr-like superfamily A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 23-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 Gene3D G3DSA:3.20.20.60 308 619 7.5E-102 T 23-10-2018 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 SUPERFAMILY SSF52009 207 320 6.15E-16 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L12_04780 77e3a93baf4a799382304a76dc5b4bae 628 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 127 609 2.7E-122 T 23-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A3L12_05300 84b7d42e9d97b22d3364deaef6252cef 256 Gene3D G3DSA:3.40.1210.10 3 255 1.8E-82 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L12_05300 84b7d42e9d97b22d3364deaef6252cef 256 SUPERFAMILY SSF64167 3 252 4.19E-71 T 23-10-2018 A3L12_05300 84b7d42e9d97b22d3364deaef6252cef 256 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 244 4.2E-68 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L12_05300 84b7d42e9d97b22d3364deaef6252cef 256 Pfam PF01975 Survival protein SurE 4 194 3.9E-54 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L12_05300 84b7d42e9d97b22d3364deaef6252cef 256 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 256 31.562 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L12_07590 5465d0a06cd75432e7ebe9497accffa9 106 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 7 95 2.9E-34 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 A3L12_07590 5465d0a06cd75432e7ebe9497accffa9 106 Gene3D G3DSA:1.10.10.10 9 103 1.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07590 5465d0a06cd75432e7ebe9497accffa9 106 SUPERFAMILY SSF46785 15 104 1.36E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01420 7010a0bdb7758b601e052c849274909d 189 Gene3D G3DSA:3.50.30.50 1 188 1.4E-57 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L12_01420 7010a0bdb7758b601e052c849274909d 189 Pfam PF04199 Putative cyclase 3 134 6.1E-23 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L12_01420 7010a0bdb7758b601e052c849274909d 189 SUPERFAMILY SSF102198 2 188 1.44E-53 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L12_03395 1a393fc3b3ade8edd5171cef31d24c0a 203 Gene3D G3DSA:3.40.50.150 1 203 2.3E-65 T 23-10-2018 A3L12_03395 1a393fc3b3ade8edd5171cef31d24c0a 203 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 40 119 2.0E-12 T 23-10-2018 A3L12_03395 1a393fc3b3ade8edd5171cef31d24c0a 203 SUPERFAMILY SSF53335 3 201 2.17E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03395 1a393fc3b3ade8edd5171cef31d24c0a 203 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 327 4.3E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 5.9E-25 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 Gene3D G3DSA:3.40.50.300 162 356 2.6E-56 T 23-10-2018 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 Gene3D G3DSA:1.20.120.1190 1 161 1.6E-51 T 23-10-2018 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 SUPERFAMILY SSF52540 168 350 1.11E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 2.4E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 2.4E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_06235 d613ecbc776f5a886ccfebca4479a1dd 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 2.4E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_01310 98acd3faca29bf0df3ca71574ea9be7c 388 SMART SM00320 100 138 9.5E-4 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L12_01310 98acd3faca29bf0df3ca71574ea9be7c 388 Pfam PF13360 PQQ-like domain 78 218 1.9E-6 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L12_01310 98acd3faca29bf0df3ca71574ea9be7c 388 Gene3D G3DSA:2.130.10.10 18 332 1.3E-21 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L12_01310 98acd3faca29bf0df3ca71574ea9be7c 388 SUPERFAMILY SSF50978 35 345 6.8E-20 T 23-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 2.1E-36 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 SUPERFAMILY SSF56276 3 117 6.08E-41 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 Gene3D G3DSA:3.30.160.750 63 125 1.8E-23 T 23-10-2018 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 30.956 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 5.6E-43 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L12_02420 ec8c2125ccb4037cb5d177e97e067142 134 Gene3D G3DSA:3.30.360.110 1 62 3.5E-18 T 23-10-2018 A3L12_04920 bf8b2748f37b17cbc5b2cced7e79d917 324 Gene3D G3DSA:3.90.1150.10 19 318 7.0E-63 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_04920 bf8b2748f37b17cbc5b2cced7e79d917 324 SUPERFAMILY SSF53383 13 320 5.71E-52 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_04920 bf8b2748f37b17cbc5b2cced7e79d917 324 Pfam PF00155 Aminotransferase class I and II 65 318 2.6E-29 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_04920 bf8b2748f37b17cbc5b2cced7e79d917 324 Gene3D G3DSA:3.40.640.10 31 236 7.0E-63 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_04920 bf8b2748f37b17cbc5b2cced7e79d917 324 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 191 200 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L12_02845 08c241956039f3171479f160913605db 382 Gene3D G3DSA:3.40.50.2000 4 219 4.8E-14 T 23-10-2018 A3L12_02845 08c241956039f3171479f160913605db 382 Gene3D G3DSA:3.40.50.2000 220 372 5.8E-20 T 23-10-2018 A3L12_02845 08c241956039f3171479f160913605db 382 Pfam PF13439 Glycosyltransferase Family 4 23 203 6.2E-13 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L12_02845 08c241956039f3171479f160913605db 382 Pfam PF13692 Glycosyl transferases group 1 224 353 1.3E-21 T 23-10-2018 A3L12_02845 08c241956039f3171479f160913605db 382 SUPERFAMILY SSF53756 21 373 1.1E-35 T 23-10-2018 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 Pfam PF00677 Lumazine binding domain 4 75 1.3E-13 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 Pfam PF00677 Lumazine binding domain 88 171 6.5E-22 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 SUPERFAMILY SSF63380 2 81 1.7E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 SUPERFAMILY SSF63380 81 183 4.34E-28 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 PIRSF PIRSF000498 1 192 5.4E-57 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 Gene3D G3DSA:2.40.30.20 90 187 2.8E-27 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 25 187 9.1E-52 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03055 5f0568e2f232c84f9b130f5970d7eb37 197 Gene3D G3DSA:2.40.30.20 1 77 1.4E-16 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 SUPERFAMILY SSF50249 4 100 1.63E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 Gene3D G3DSA:2.40.50.140 1 102 2.3E-29 T 23-10-2018 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 2.4E-125 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 Gene3D G3DSA:3.30.930.10 105 430 2.2E-116 T 23-10-2018 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 4.4E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 110 424 5.1E-87 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_07050 3b9a1fa080124d88237708fef456e19a 430 SUPERFAMILY SSF55681 110 425 2.6E-88 T 23-10-2018 A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 Gene3D G3DSA:1.10.10.460 162 208 3.7E-24 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 Pfam PF01351 Ribonuclease HII 4 200 1.7E-53 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 SUPERFAMILY SSF53098 3 207 5.46E-60 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 Gene3D G3DSA:3.30.420.10 2 161 4.3E-58 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.567 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A3L12_07940 1d05e55595d152c0cdd82e2f70d1845c 231 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 205 1.3E-77 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A3L12_06580 4de506c88f03cad54dfde182ef91de6c 235 SUPERFAMILY SSF56300 1 235 4.43E-62 T 23-10-2018 A3L12_06580 4de506c88f03cad54dfde182ef91de6c 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 5.0E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_06580 4de506c88f03cad54dfde182ef91de6c 235 Gene3D G3DSA:3.60.21.10 2 235 1.8E-68 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_06580 4de506c88f03cad54dfde182ef91de6c 235 PIRSF PIRSF000883 1 235 3.0E-68 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L12_01190 d44bcc8061ecc7377b95b4491d7b99c0 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 1.3E-43 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_01190 d44bcc8061ecc7377b95b4491d7b99c0 333 Gene3D G3DSA:1.10.3720.10 94 327 3.7E-25 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01190 d44bcc8061ecc7377b95b4491d7b99c0 333 SUPERFAMILY SSF161098 96 320 2.94E-19 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 SUPERFAMILY SSF52540 133 438 2.78E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 Pfam PF00437 Type II/IV secretion system protein 214 370 2.6E-8 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 SUPERFAMILY SSF54814 465 522 3.14E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 SMART SM00670 2 115 2.3E-21 T 23-10-2018 IPR002716 PIN domain A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 Gene3D G3DSA:3.40.50.1010 1 127 1.2E-32 T 23-10-2018 A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 Gene3D G3DSA:3.40.50.300 235 392 1.4E-17 T 23-10-2018 A3L12_06650 71c0ebcf616ca0505125e1bae5d64631 602 SUPERFAMILY SSF88723 3 131 1.34E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_03565 c938e80403ea3d253c805a008088f06b 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L12_03565 c938e80403ea3d253c805a008088f06b 188 Gene3D G3DSA:1.20.120.1760 7 187 5.4E-49 T 23-10-2018 A3L12_03565 c938e80403ea3d253c805a008088f06b 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 1.1E-15 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 SUPERFAMILY SSF55120 8 413 4.46E-92 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 Gene3D G3DSA:1.10.1510.30 171 256 1.6E-113 T 23-10-2018 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 Gene3D G3DSA:3.30.2350.20 126 410 1.6E-113 T 23-10-2018 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 411 2.7E-129 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 PIRSF PIRSF037016 21 392 5.8E-60 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 PIRSF PIRSF037016 388 415 0.014 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 414 2.9E-82 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 415 29.164 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06280 8f62da588426f5e2dc10eea34d5eaec4 415 Gene3D G3DSA:3.30.70.3160 43 125 1.6E-113 T 23-10-2018 A3L12_06915 a936c3cab416feeb2d90b0f9b8db244e 149 Gene3D G3DSA:1.10.10.10 1 100 2.6E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06915 a936c3cab416feeb2d90b0f9b8db244e 149 SUPERFAMILY SSF46785 6 94 6.57E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06915 a936c3cab416feeb2d90b0f9b8db244e 149 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.7E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L12_03065 b97c3df6bdce1c80f2ce619753e4b9a1 148 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 145 1.7E-48 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03065 b97c3df6bdce1c80f2ce619753e4b9a1 148 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 11 146 1.3E-51 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03065 b97c3df6bdce1c80f2ce619753e4b9a1 148 SUPERFAMILY SSF52121 2 147 1.57E-53 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03065 b97c3df6bdce1c80f2ce619753e4b9a1 148 Gene3D G3DSA:3.40.50.960 1 148 2.4E-55 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03065 b97c3df6bdce1c80f2ce619753e4b9a1 148 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 148 26.735 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_06230 bfff2f587622aa1f367e3e113cded606 258 Pfam PF02673 Bacitracin resistance protein BacA 11 234 6.4E-20 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 Pfam PF01199 Ribosomal protein L34e 3 83 2.6E-23 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 Gene3D G3DSA:3.40.1800.40 29 87 2.5E-8 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 PRINTS PR01250 Ribosomal protein L34 signature 5 18 1.5E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 PRINTS PR01250 Ribosomal protein L34 signature 18 35 1.5E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 PRINTS PR01250 Ribosomal protein L34 signature 56 78 1.5E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 PRINTS PR01250 Ribosomal protein L34 signature 36 46 1.5E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 28.343 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00725 ca152bbe21a0b3b943d1406de6724abf 89 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 SUPERFAMILY SSF56784 7 264 1.68E-71 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 2.0E-29 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 Gene3D G3DSA:3.40.50.1000 72 188 5.8E-95 T 23-10-2018 IPR023214 HAD superfamily A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 Gene3D G3DSA:3.40.50.1000 8 256 5.8E-95 T 23-10-2018 IPR023214 HAD superfamily A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 238 4.1E-48 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 PIRSF PIRSF000915 4 268 9.0E-67 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L12_02780 c4e127e870de390ebe38e8cd933119ef 274 Pfam PF13242 HAD-hyrolase-like 188 262 1.3E-20 T 23-10-2018 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 SMART SM00790 4 205 1.1E-118 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 Gene3D G3DSA:3.60.9.10 1 209 5.7E-91 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 SUPERFAMILY SSF48310 211 619 8.76E-127 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 1.4E-77 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 SUPERFAMILY SSF56228 1 209 1.1E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 Gene3D G3DSA:1.10.599.10 237 606 7.1E-131 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 Gene3D G3DSA:1.10.569.10 239 418 7.1E-131 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L12_07845 24d4571dabbfc58f4efc253eb7cb687b 620 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 606 2.8E-113 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07225 473a94095622dd9a32e94a3ba0775526 153 SUPERFAMILY SSF55620 10 150 1.22E-34 T 23-10-2018 A3L12_07225 473a94095622dd9a32e94a3ba0775526 153 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 8.0E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L12_07225 473a94095622dd9a32e94a3ba0775526 153 Gene3D G3DSA:3.30.479.10 12 150 1.1E-30 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 SUPERFAMILY SSF52540 2 222 1.57E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 Gene3D G3DSA:3.40.50.300 1 225 1.9E-50 T 23-10-2018 A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 Pfam PF06745 KaiC 4 223 2.0E-51 T 23-10-2018 IPR014774 KaiC-like domain A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 Pfam PF06745 KaiC 239 448 4.1E-31 T 23-10-2018 IPR014774 KaiC-like domain A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 PIRSF PIRSF039117 1 449 5.8E-120 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 SUPERFAMILY SSF52540 234 447 5.54E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 Gene3D G3DSA:3.40.50.300 227 449 2.1E-50 T 23-10-2018 A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 SMART SM00382 21 194 0.21 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 SMART SM00382 256 428 0.0084 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 PRINTS PR01874 DNA repair protein radA signature 154 182 1.6E-9 T 23-10-2018 A3L12_03390 8a57f9d67cf81a10e5ad7844996f61cd 449 PRINTS PR01874 DNA repair protein radA signature 13 41 1.6E-9 T 23-10-2018 A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 Gene3D G3DSA:3.30.70.20 36 67 1.1E-6 T 23-10-2018 A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 SUPERFAMILY SSF54862 3 64 1.38E-17 T 23-10-2018 A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 Gene3D G3DSA:3.30.70.20 1 35 1.3E-6 T 23-10-2018 A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 Pfam PF00037 4Fe-4S binding domain 7 30 3.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 Pfam PF00037 4Fe-4S binding domain 38 58 1.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01965 83ff61710c4ab8ddc6b24a0d2e18b8d0 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 SUPERFAMILY SSF52540 259 494 1.47E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 Pfam PF00005 ABC transporter 23 173 3.4E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 Gene3D G3DSA:3.40.50.300 256 500 4.7E-44 T 23-10-2018 A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 SMART SM00382 32 221 5.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 Pfam PF00005 ABC transporter 278 434 9.5E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 Gene3D G3DSA:3.40.50.300 1 240 3.3E-57 T 23-10-2018 A3L12_05265 aab59c09614ec1c808e266e50f05406e 512 SUPERFAMILY SSF52540 5 231 3.76E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00830 09d10ce125023a4e67214be325f849bd 113 SUPERFAMILY SSF46785 3 100 2.38E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00830 09d10ce125023a4e67214be325f849bd 113 Pfam PF03551 Transcriptional regulator PadR-like family 17 89 6.2E-17 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L12_00830 09d10ce125023a4e67214be325f849bd 113 Gene3D G3DSA:1.10.10.10 1 113 5.2E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 SUPERFAMILY SSF143437 31 132 2.09E-8 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 Gene3D G3DSA:3.30.2130.30 12 139 1.2E-5 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 SMART SM00981 56 143 4.1E-6 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 Pfam PF02926 THUMP domain 41 140 3.9E-9 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 SUPERFAMILY SSF53335 145 292 2.07E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 250 256 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 Gene3D G3DSA:3.40.50.150 153 330 2.5E-35 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 2.0E-6 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 269 293 2.0E-6 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 247 259 2.0E-6 T 23-10-2018 A3L12_07345 e36df335947ca4524fcd33bc47da36ba 330 Pfam PF01170 Putative RNA methylase family UPF0020 155 296 2.8E-29 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L12_02435 700b4234151924c29fab71586bbf71be 230 Pfam PF02254 TrkA-N domain 3 124 1.9E-28 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L12_02435 700b4234151924c29fab71586bbf71be 230 Pfam PF02080 TrkA-C domain 153 221 1.7E-11 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L12_02435 700b4234151924c29fab71586bbf71be 230 Gene3D G3DSA:3.30.70.1450 140 223 3.1E-14 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_02435 700b4234151924c29fab71586bbf71be 230 SUPERFAMILY SSF51735 1 145 9.53E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02435 700b4234151924c29fab71586bbf71be 230 Gene3D G3DSA:3.40.50.720 3 137 5.8E-41 T 23-10-2018 A3L12_02435 700b4234151924c29fab71586bbf71be 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 5.9E-15 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L12_02435 700b4234151924c29fab71586bbf71be 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 5.9E-15 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L12_02435 700b4234151924c29fab71586bbf71be 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 5.9E-15 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L12_02435 700b4234151924c29fab71586bbf71be 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 5.9E-15 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L12_02435 700b4234151924c29fab71586bbf71be 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 5.9E-15 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L12_02435 700b4234151924c29fab71586bbf71be 230 SUPERFAMILY SSF116726 135 221 5.75E-11 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 SUPERFAMILY SSF53271 233 440 3.41E-70 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 Pfam PF13537 Glutamine amidotransferase domain 72 199 3.0E-16 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 Pfam PF00156 Phosphoribosyl transferase domain 265 369 2.9E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 438 4.8E-157 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 Gene3D G3DSA:3.40.50.2020 258 422 1.6E-139 T 23-10-2018 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 PIRSF PIRSF000485 1 443 7.0E-153 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 437 44.355 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 Gene3D G3DSA:3.60.20.10 5 438 1.6E-139 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_03110 0d841fe67e5793b547d14c82cc1a4938 446 SUPERFAMILY SSF56235 5 240 2.14E-53 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 Pfam PF00557 Metallopeptidase family M24 131 333 8.2E-71 T 23-10-2018 IPR000994 Peptidase M24 A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 SUPERFAMILY SSF55920 123 347 2.75E-84 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 3.9E-22 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 Gene3D G3DSA:3.90.230.10 123 348 1.9E-90 T 23-10-2018 A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 Gene3D G3DSA:3.40.350.10 1 122 4.0E-28 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L12_05055 27e8a62b1074881b632b99c80d55bfc0 348 SUPERFAMILY SSF53092 6 124 1.92E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 15 570 3.4E-265 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 Pfam PF16199 Radical_SAM C-terminal domain 333 412 4.5E-26 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 PIRSF PIRSF005669 1 571 2.0E-250 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 Pfam PF00583 Acetyltransferase (GNAT) family 454 559 6.0E-8 T 23-10-2018 IPR000182 GNAT domain A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 SUPERFAMILY SSF102114 83 379 1.44E-34 T 23-10-2018 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 Gene3D G3DSA:3.40.630.30 420 571 1.0E-8 T 23-10-2018 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 SUPERFAMILY SSF55729 442 566 7.21E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 Pfam PF04055 Radical SAM superfamily 85 317 1.1E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 SMART SM00729 78 372 3.8E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_02385 8f7fb1382745a40299264e31606c86e3 590 Gene3D G3DSA:3.80.30.20 226 379 6.3E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L12_05060 7997e37ca1296464201b6a813e9aa46e 217 Gene3D G3DSA:1.10.150.520 15 84 4.7E-9 T 23-10-2018 A3L12_05060 7997e37ca1296464201b6a813e9aa46e 217 SUPERFAMILY SSF56784 4 187 1.07E-15 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_05060 7997e37ca1296464201b6a813e9aa46e 217 Gene3D G3DSA:3.40.50.1000 4 134 4.7E-9 T 23-10-2018 IPR023214 HAD superfamily A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Gene3D G3DSA:2.30.130.10 87 161 3.1E-15 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 SMART SM00359 90 164 5.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Pfam PF01189 16S rRNA methyltransferase RsmB/F 192 381 7.4E-55 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 SUPERFAMILY SSF88697 89 160 1.16E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Gene3D G3DSA:3.30.70.3130 2 84 7.0E-12 T 23-10-2018 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 77 1.5E-6 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 84 159 3.5E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 SUPERFAMILY SSF53335 5 383 2.07E-57 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Pfam PF01472 PUA domain 93 159 2.0E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 Gene3D G3DSA:3.40.50.150 189 383 1.6E-61 T 23-10-2018 A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 1.8E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 1.8E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 1.8E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 1.8E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_04685 eb05da0fcf2f98cdd0ba4d4ffcd3d9ef 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 1.8E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_06680 c20b0367ccb7d4dad970886bcf7be348 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 2.4E-24 T 23-10-2018 A3L12_06680 c20b0367ccb7d4dad970886bcf7be348 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 6.2E-52 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A3L12_06680 c20b0367ccb7d4dad970886bcf7be348 133 Gene3D G3DSA:3.10.180.10 1 132 5.1E-42 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L12_06680 c20b0367ccb7d4dad970886bcf7be348 133 SUPERFAMILY SSF54593 1 131 1.17E-33 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 SUPERFAMILY SSF52490 38 235 2.88E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 Gene3D G3DSA:3.30.1330.20 254 363 1.4E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 3.1E-46 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 SUPERFAMILY SSF55307 233 347 1.56E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 PRINTS PR00423 Cell division protein FtsZ signature 128 148 5.5E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 PRINTS PR00423 Cell division protein FtsZ signature 156 177 5.5E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 PRINTS PR00423 Cell division protein FtsZ signature 218 240 5.5E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 PRINTS PR00423 Cell division protein FtsZ signature 241 262 5.5E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 Gene3D G3DSA:3.40.50.1440 34 249 1.1E-82 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 SMART SM00864 43 234 3.0E-106 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 370 38.164 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 Pfam PF12327 FtsZ family, C-terminal domain 251 343 2.8E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 355 1.4E-135 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 SMART SM00865 236 352 9.2E-50 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L12_02000 a72718746ea2fa72faa615c74a02b239 372 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 156 240 8.1E-11 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 511 530 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 433 445 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 3.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 SUPERFAMILY SSF52954 460 565 2.72E-31 T 23-10-2018 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Gene3D G3DSA:1.10.30.30 351 424 2.4E-135 T 23-10-2018 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Pfam PF03129 Anticodon binding domain 473 563 4.4E-23 T 23-10-2018 IPR004154 Anticodon-binding A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 SUPERFAMILY SSF55681 3 476 9.1E-115 T 23-10-2018 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 563 4.7E-209 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Gene3D G3DSA:3.30.930.10 12 456 2.4E-135 T 23-10-2018 A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Gene3D G3DSA:3.40.50.800 471 567 1.6E-30 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L12_05095 f43f55c8583e0fd64db58ff911626b4b 567 Gene3D G3DSA:1.20.1430.20 82 145 2.4E-135 T 23-10-2018 A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 31.315 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 1.6E-55 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 SUPERFAMILY SSF50104 6 116 3.1E-37 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 7.0E-34 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 SMART SM00739 45 72 2.1E-6 T 23-10-2018 IPR005824 KOW A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 Pfam PF00467 KOW motif 48 79 1.7E-9 T 23-10-2018 IPR005824 KOW A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 Gene3D G3DSA:2.30.30.30 1 121 8.7E-51 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_00650 da96b8dcf7f98efeec549fbcc6342d83 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 Gene3D G3DSA:3.40.50.720 95 286 1.5E-107 T 23-10-2018 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 Gene3D G3DSA:3.40.50.720 14 318 1.5E-107 T 23-10-2018 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 7.5E-51 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 SUPERFAMILY SSF52283 1 132 4.46E-33 T 23-10-2018 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 SUPERFAMILY SSF51735 100 286 4.13E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L12_05380 ac1820a00795a3cc23df2efa65fcc856 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 318 9.3E-32 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 SMART SM00849 19 235 8.8E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 Pfam PF00753 Metallo-beta-lactamase superfamily 18 79 2.6E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 Pfam PF12706 Beta-lactamase superfamily domain 197 263 8.4E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 SUPERFAMILY SSF56281 3 275 2.64E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 276 1.3E-93 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 Hamap MF_01818 Ribonuclease BN [rbn]. 2 297 33.962 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L12_01855 10ecae7e0e560fa03caf7d8a791068d1 312 Gene3D G3DSA:3.60.15.10 1 296 2.4E-81 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_05015 abb69c374bde0bd34f3daab8b505d933 267 Gene3D G3DSA:3.40.1700.10 178 265 1.6E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L12_05015 abb69c374bde0bd34f3daab8b505d933 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 33.748 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L12_05015 abb69c374bde0bd34f3daab8b505d933 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 5.6E-20 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A3L12_05015 abb69c374bde0bd34f3daab8b505d933 267 SUPERFAMILY SSF143597 89 260 2.22E-30 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L12_05015 abb69c374bde0bd34f3daab8b505d933 267 PIRSF PIRSF019073 3 267 4.6E-77 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 SMART SM00962 104 299 8.0E-113 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 297 2.9E-107 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 58.329 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 SUPERFAMILY SSF52540 101 299 8.22E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 SUPERFAMILY SSF47364 2 89 1.74E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 Pfam PF02881 SRP54-type protein, helical bundle domain 5 80 6.8E-15 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 SMART SM00382 103 298 1.1E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 9.4E-78 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 Gene3D G3DSA:1.20.120.140 3 87 2.4E-22 T 23-10-2018 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 Gene3D G3DSA:3.40.50.300 90 298 3.0E-85 T 23-10-2018 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 SMART SM00963 1 85 5.0E-16 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_05295 a8ecd25c9321637ed596bda49c045e88 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_06670 7551792a2f7023bce11f336f77223a89 142 Pfam PF02310 B12 binding domain 8 121 2.0E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L12_06670 7551792a2f7023bce11f336f77223a89 142 SUPERFAMILY SSF52242 5 133 1.31E-49 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L12_06670 7551792a2f7023bce11f336f77223a89 142 Gene3D G3DSA:3.40.50.280 1 141 1.2E-57 T 23-10-2018 A3L12_06670 7551792a2f7023bce11f336f77223a89 142 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 5 138 7.5E-61 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L12_02885 a3c7dc105c4688e3d6105902ad42af80 144 Gene3D G3DSA:3.40.50.1010 1 127 1.5E-9 T 23-10-2018 A3L12_02885 a3c7dc105c4688e3d6105902ad42af80 144 SUPERFAMILY SSF88723 1 140 1.01E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_02885 a3c7dc105c4688e3d6105902ad42af80 144 Pfam PF01850 PIN domain 2 116 3.9E-8 T 23-10-2018 IPR002716 PIN domain A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1340 1359 1.6E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 SUPERFAMILY SSF49344 1035 1265 3.73E-79 T 23-10-2018 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 SUPERFAMILY SSF49344 791 1025 1.1E-78 T 23-10-2018 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 SUPERFAMILY SSF88713 32 576 2.28E-66 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Gene3D G3DSA:3.20.110.20 230 501 7.9E-25 T 23-10-2018 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Pfam PF03065 Glycosyl hydrolase family 57 36 537 4.0E-130 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 792 1024 1.3E-77 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1036 1264 4.8E-78 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Gene3D G3DSA:2.60.40.1190 789 1028 8.3E-67 T 23-10-2018 A3L12_02630 2ac9124a7669e80683f17e5aeb8ef2ec 1359 Gene3D G3DSA:2.60.40.1190 1034 1267 6.0E-66 T 23-10-2018 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 Pfam PF00005 ABC transporter 355 503 1.3E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 Gene3D G3DSA:3.40.50.300 335 578 6.6E-89 T 23-10-2018 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 Pfam PF00664 ABC transporter transmembrane region 24 294 6.2E-58 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 SUPERFAMILY SSF52540 331 575 1.11E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 Gene3D G3DSA:1.20.1560.10 1 326 1.2E-93 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 SUPERFAMILY SSF90123 11 322 6.15E-82 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L12_03595 b38249b40017a7b74880fdee08aa5ef8 578 SMART SM00382 364 550 3.1E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.202 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 244 299 9.4E-9 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 Pfam PF01680 SOR/SNZ family 13 210 4.4E-95 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 SUPERFAMILY SSF51366 24 312 1.04E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 PIRSF PIRSF029271 3 335 7.8E-149 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 Gene3D G3DSA:3.20.20.70 1 316 3.0E-153 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03100 34548b11f888d5df7f13aba3f2867e56 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 1.1E-144 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Gene3D G3DSA:3.10.28.10 364 530 7.9E-29 T 23-10-2018 IPR027434 Homing endonuclease A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 584 608 3.0E-5 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SMART SM00306 153 275 3.4E-18 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SUPERFAMILY SSF102114 127 163 9.03E-8 T 23-10-2018 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Pfam PF14890 Intein splicing domain 203 603 6.6E-28 T 23-10-2018 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 PRINTS PR00379 Intein signature 238 251 4.3E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 PRINTS PR00379 Intein signature 492 507 4.3E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 PRINTS PR00379 Intein signature 368 380 4.3E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 PRINTS PR00379 Intein signature 462 474 4.3E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 PRINTS PR00379 Intein signature 582 599 4.3E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Pfam PF04055 Radical SAM superfamily 608 754 3.6E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SMART SM00305 565 613 1.0E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SUPERFAMILY SSF55608 365 420 1.98E-5 T 23-10-2018 IPR027434 Homing endonuclease A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Pfam PF14528 LAGLIDADG-like domain 461 540 7.0E-13 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 155 251 1.4E-11 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SUPERFAMILY SSF102114 608 846 1.31E-31 T 23-10-2018 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SUPERFAMILY SSF55608 445 541 1.81E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 SUPERFAMILY SSF51294 155 608 1.81E-33 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Gene3D G3DSA:2.170.16.10 156 309 7.0E-24 T 23-10-2018 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Gene3D G3DSA:2.170.16.10 531 606 1.6E-6 T 23-10-2018 A3L12_04330 878a2e52bc4b1801c562c53de62c9bef 1045 Gene3D G3DSA:3.20.20.70 607 853 7.3E-23 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04525 1d38adee8f94eee57eb539053d0522e8 133 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_04525 1d38adee8f94eee57eb539053d0522e8 133 Pfam PF12838 4Fe-4S dicluster domain 45 91 1.5E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_04525 1d38adee8f94eee57eb539053d0522e8 133 SUPERFAMILY SSF54862 27 110 2.16E-23 T 23-10-2018 A3L12_04525 1d38adee8f94eee57eb539053d0522e8 133 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_04525 1d38adee8f94eee57eb539053d0522e8 133 Gene3D G3DSA:3.30.70.3270 23 133 9.2E-22 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Gene3D G3DSA:1.10.1410.30 9 276 2.3E-82 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Gene3D G3DSA:3.30.460.10 16 152 2.3E-82 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Gene3D G3DSA:3.30.70.1550 357 396 1.8E-22 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 SUPERFAMILY SSF81301 1 150 1.24E-31 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 SUPERFAMILY SSF81631 153 277 3.53E-36 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 SUPERFAMILY SSF55003 264 446 1.53E-38 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Pfam PF01909 Nucleotidyltransferase domain 35 141 3.9E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 276 6.6E-38 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Gene3D G3DSA:3.30.70.590 288 424 1.8E-22 T 23-10-2018 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 415 1.7E-134 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 PIRSF PIRSF005335 1 451 1.9E-146 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L12_02730 f36ee29809a7104c3858f6c4bf35ee42 452 Hamap MF_01264 CCA-adding enzyme [cca]. 1 452 154.69 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 Gene3D G3DSA:2.40.50.140 58 158 5.3E-21 T 23-10-2018 A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 SUPERFAMILY SSF50249 53 175 1.84E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 SUPERFAMILY SSF50249 179 342 1.58E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 Pfam PF01336 OB-fold nucleic acid binding domain 79 151 1.7E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 Pfam PF08646 Replication factor-A C terminal domain 193 284 2.2E-10 T 23-10-2018 IPR013955 Replication factor A, C-terminal A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 Gene3D G3DSA:2.40.50.140 166 345 1.1E-13 T 23-10-2018 A3L12_03495 6735226c8c23165bbd9246dbd1c02e91 354 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 7 55 3.8E-4 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 SUPERFAMILY SSF55681 3 169 1.56E-47 T 23-10-2018 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 Pfam PF02237 Biotin protein ligase C terminal domain 185 230 7.9E-5 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 7 230 1.6E-51 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 Gene3D G3DSA:2.30.30.100 184 231 2.8E-11 T 23-10-2018 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 Pfam PF03099 Biotin/lipoate A/B protein ligase family 22 123 1.4E-16 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 SUPERFAMILY SSF50037 185 230 2.56E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L12_07325 fb98bc6129fa205f89e212901121c0d5 232 Gene3D G3DSA:3.30.930.10 1 183 1.1E-53 T 23-10-2018 A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 SUPERFAMILY SSF56024 129 213 6.43E-5 T 23-10-2018 A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 SMART SM00487 263 438 0.0012 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 Gene3D G3DSA:3.40.50.300 644 854 1.4E-36 T 23-10-2018 A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 Gene3D G3DSA:3.40.50.10810 266 471 6.1E-14 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 SMART SM00490 729 820 7.5E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 Pfam PF00271 Helicase conserved C-terminal domain 702 820 4.0E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 SUPERFAMILY SSF52540 265 473 1.17E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 Pfam PF13091 PLD-like domain 35 207 8.0E-10 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A3L12_05745 eeea2bc31affc02907865ce65e0ddc73 1139 SUPERFAMILY SSF52540 374 863 5.32E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 Gene3D G3DSA:3.40.50.920 284 395 2.7E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 SUPERFAMILY SSF52922 286 393 5.71E-24 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 SUPERFAMILY SSF52518 23 278 1.23E-64 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 5.9E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 7.8E-74 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_05315 99a94aa8cc1229769c6f8eed56c82803 396 Gene3D G3DSA:3.40.50.970 14 211 2.5E-75 T 23-10-2018 A3L12_06385 5c3bd51d0988b5e7611f73208b0663ca 362 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 21 266 2.4E-39 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L12_06385 5c3bd51d0988b5e7611f73208b0663ca 362 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 27 262 3.2E-14 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L12_06385 5c3bd51d0988b5e7611f73208b0663ca 362 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 14 350 1.6E-78 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 40 213 3.7E-68 T 23-10-2018 IPR019964 KH domain protein, archaea A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 SMART SM00322 34 104 3.6E-10 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 SMART SM00322 118 192 2.6E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 Pfam PF00013 KH domain 141 188 5.0E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 Pfam PF00013 KH domain 38 85 2.5E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 SUPERFAMILY SSF54791 38 112 1.31E-12 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 Gene3D G3DSA:3.30.1370.10 34 116 4.8E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 SUPERFAMILY SSF54791 133 203 3.36E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_07905 08a7ef552014bb06b9ecd2a2fabdb321 229 Gene3D G3DSA:3.30.1370.10 117 221 2.4E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 PIRSF PIRSF001109 1 421 4.6E-195 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.35 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 418 3.9E-30 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 SMART SM00996 6 420 1.4E-143 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 SMART SM00997 188 349 1.6E-110 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Gene3D G3DSA:3.40.50.1480 9 410 7.1E-177 T 23-10-2018 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 SUPERFAMILY SSF51735 188 350 1.85E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 1.1E-207 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Gene3D G3DSA:3.40.50.720 190 349 7.1E-177 T 23-10-2018 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.2E-51 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 9.7E-33 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L12_01425 bf54e7b9e2ae9f1c8c970c0b061e0ade 421 SUPERFAMILY SSF52283 5 421 7.37E-101 T 23-10-2018 A3L12_00505 00290c25b49940ac380c2ff7fa96a249 120 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 77 6.3E-13 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L12_00505 00290c25b49940ac380c2ff7fa96a249 120 PIRSF PIRSF018867 1 117 7.5E-30 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit A3L12_00505 00290c25b49940ac380c2ff7fa96a249 120 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 80 1.2E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L12_01325 767429707d4684fab36675b881fdd129 645 Gene3D G3DSA:3.60.21.10 123 407 8.3E-19 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_01325 767429707d4684fab36675b881fdd129 645 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 625 644 1.6E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L12_01325 767429707d4684fab36675b881fdd129 645 SUPERFAMILY SSF56300 124 404 8.23E-34 T 23-10-2018 A3L12_01325 767429707d4684fab36675b881fdd129 645 Pfam PF00149 Calcineurin-like phosphoesterase 124 355 9.6E-13 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Gene3D G3DSA:3.40.120.10 161 342 8.1E-45 T 23-10-2018 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 436 1.2E-143 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 SUPERFAMILY SSF53738 146 247 3.3E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Gene3D G3DSA:3.40.120.10 245 325 8.1E-45 T 23-10-2018 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Gene3D G3DSA:3.30.310.50 352 451 1.8E-16 T 23-10-2018 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 128 2.1E-39 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 87 96 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 355 8.6E-6 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 148 244 9.1E-26 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 SUPERFAMILY SSF53738 250 346 5.89E-9 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Gene3D G3DSA:3.40.120.10 1 144 5.8E-46 T 23-10-2018 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 SUPERFAMILY SSF55957 353 447 1.96E-18 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 432 4.5E-10 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 SUPERFAMILY SSF53738 2 168 2.79E-42 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 196 209 4.5E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 239 4.5E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 86 100 4.5E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_02615 39367eee46561e44d75f85c40420a3ff 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 162 181 4.5E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_00300 703cc0be49edb65a08d315bb4886ef30 445 Pfam PF00860 Permease family 20 402 1.9E-46 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L12_00300 703cc0be49edb65a08d315bb4886ef30 445 PIRSF PIRSF005353 1 442 4.9E-166 T 23-10-2018 IPR026033 Purine permease PbuG-like A3L12_01525 9185d71d2cfd91b5b48db5c478f9b3dd 316 SUPERFAMILY SSF53613 2 303 2.65E-74 T 23-10-2018 IPR029056 Ribokinase-like A3L12_01525 9185d71d2cfd91b5b48db5c478f9b3dd 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L12_01525 9185d71d2cfd91b5b48db5c478f9b3dd 316 Gene3D G3DSA:3.40.1190.20 1 316 2.2E-105 T 23-10-2018 IPR029056 Ribokinase-like A3L12_01525 9185d71d2cfd91b5b48db5c478f9b3dd 316 Pfam PF00294 pfkB family carbohydrate kinase 2 293 7.0E-59 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L12_07465 02427d3c795fad53643a6f078e8763db 294 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 2 270 1.8E-91 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L12_07465 02427d3c795fad53643a6f078e8763db 294 Pfam PF16916 Dimerisation domain of Zinc Transporter 200 269 1.5E-9 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L12_07465 02427d3c795fad53643a6f078e8763db 294 Gene3D G3DSA:1.20.1510.10 1 192 4.1E-47 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L12_07465 02427d3c795fad53643a6f078e8763db 294 SUPERFAMILY SSF160240 196 270 4.45E-14 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L12_07465 02427d3c795fad53643a6f078e8763db 294 Pfam PF01545 Cation efflux family 2 192 3.4E-50 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L12_07465 02427d3c795fad53643a6f078e8763db 294 Gene3D G3DSA:3.30.70.1350 193 271 1.0E-6 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L12_07465 02427d3c795fad53643a6f078e8763db 294 SUPERFAMILY SSF161111 2 193 5.62E-56 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 Pfam PF13353 4Fe-4S single cluster domain 18 105 4.3E-10 T 23-10-2018 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 SMART SM00729 12 228 1.6E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 42.887 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 SUPERFAMILY SSF102114 4 301 5.76E-70 T 23-10-2018 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 Gene3D G3DSA:3.20.20.70 1 306 4.9E-78 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 Pfam PF04055 Radical SAM superfamily 16 172 3.3E-33 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 4 308 7.2E-124 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L12_03760 d85a9f208585ca75c8480a4b6583e55f 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 306 4.0E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 SUPERFAMILY SSF52540 5 263 1.69E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 1.1E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 SMART SM00382 45 249 1.8E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 Pfam PF00005 ABC transporter 37 191 4.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 Gene3D G3DSA:3.40.50.300 3 334 1.8E-96 T 23-10-2018 A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 1.4E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_02530 654e1f9c2338441c90cd81d60b992909 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_00085 df69781f624e8397a860d3a1acd9eb33 357 Gene3D G3DSA:1.10.1580.10 168 252 7.1E-13 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A3L12_00085 df69781f624e8397a860d3a1acd9eb33 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 2.6E-14 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_00085 df69781f624e8397a860d3a1acd9eb33 357 Gene3D G3DSA:3.40.50.300 5 162 1.8E-46 T 23-10-2018 A3L12_00085 df69781f624e8397a860d3a1acd9eb33 357 SUPERFAMILY SSF52540 4 171 7.41E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02200 246ef595c03c3c90f8f048e27bbab792 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 39.045 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A3L12_02200 246ef595c03c3c90f8f048e27bbab792 224 SMART SM00849 8 189 4.1E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_02200 246ef595c03c3c90f8f048e27bbab792 224 Pfam PF13483 Beta-lactamase superfamily domain 4 189 1.6E-31 T 23-10-2018 A3L12_02200 246ef595c03c3c90f8f048e27bbab792 224 SUPERFAMILY SSF56281 1 223 3.01E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_02200 246ef595c03c3c90f8f048e27bbab792 224 Gene3D G3DSA:3.60.15.10 2 224 2.5E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_04970 7732bbaf40c8bcf81ad497344868a00b 331 SUPERFAMILY SSF53335 72 330 1.91E-69 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_04970 7732bbaf40c8bcf81ad497344868a00b 331 Gene3D G3DSA:3.40.50.150 143 331 2.8E-56 T 23-10-2018 A3L12_04970 7732bbaf40c8bcf81ad497344868a00b 331 Gene3D G3DSA:3.30.300.110 56 142 3.9E-24 T 23-10-2018 A3L12_04970 7732bbaf40c8bcf81ad497344868a00b 331 Pfam PF02475 Met-10+ like-protein 82 277 2.5E-68 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L12_03360 de963929f31aa184ec27b3fa242e0c0d 264 Gene3D G3DSA:3.60.110.10 1 263 1.3E-104 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L12_03360 de963929f31aa184ec27b3fa242e0c0d 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 243 1.2E-60 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L12_03360 de963929f31aa184ec27b3fa242e0c0d 264 SUPERFAMILY SSF56317 1 264 9.94E-78 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 SUPERFAMILY SSF52540 4 239 1.94E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 250 2.1E-104 T 23-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 Pfam PF00005 ABC transporter 20 177 4.0E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 Gene3D G3DSA:3.40.50.300 2 250 1.7E-71 T 23-10-2018 A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_00055 8c19134f45adc66de8ddcda737a26b1d 251 SMART SM00382 28 224 4.8E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Gene3D G3DSA:3.40.50.300 209 478 2.5E-99 T 23-10-2018 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Pfam PF00270 DEAD/DEAH box helicase 14 146 7.8E-18 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SMART SM00891 564 644 6.6E-30 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SMART SM00490 372 461 5.2E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Pfam PF00271 Helicase conserved C-terminal domain 343 460 1.0E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SMART SM00487 6 201 1.6E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SUPERFAMILY SSF47781 702 771 8.15E-16 T 23-10-2018 IPR010994 RuvA domain 2-like A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Gene3D G3DSA:1.20.1320.20 212 338 2.5E-99 T 23-10-2018 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Gene3D G3DSA:3.40.50.10130 561 701 3.3E-49 T 23-10-2018 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SMART SM00278 715 734 1500.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SMART SM00278 747 766 0.036 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Gene3D G3DSA:3.40.50.300 1 199 3.9E-71 T 23-10-2018 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Pfam PF12826 Helix-hairpin-helix motif 719 770 1.6E-9 T 23-10-2018 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Pfam PF02732 ERCC4 domain 567 684 8.4E-27 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SUPERFAMILY SSF52980 564 692 3.49E-36 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 SUPERFAMILY SSF52540 52 480 5.74E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06700 8f4bfb81557af8e161d86f85d1f6d99a 781 Gene3D G3DSA:1.10.150.20 702 775 2.3E-23 T 23-10-2018 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 SUPERFAMILY SSF50465 321 424 4.68E-40 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.7E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 2.7E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 2.7E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 2.7E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.7E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 1.5E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Gene3D G3DSA:2.40.30.10 320 425 5.9E-42 T 23-10-2018 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 7.4E-38 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Gene3D G3DSA:2.40.30.10 216 310 5.7E-41 T 23-10-2018 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.3E-58 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 2.7E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 SUPERFAMILY SSF50447 213 315 3.33E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.128 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 2.4E-212 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 SUPERFAMILY SSF52540 3 236 3.44E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07865 e5a4a469ce00870d14ffd8f7dff8556c 428 Gene3D G3DSA:3.40.50.300 1 212 2.7E-86 T 23-10-2018 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Gene3D G3DSA:2.40.30.10 203 317 1.7E-45 T 23-10-2018 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Pfam PF03144 Elongation factor Tu domain 2 230 311 3.4E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 SUPERFAMILY SSF52540 4 208 3.22E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 323 407 1.3E-30 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 7 408 1.4E-204 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Pfam PF00009 Elongation factor Tu GTP binding domain 11 198 1.9E-36 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 SUPERFAMILY SSF50465 316 408 1.33E-32 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 SUPERFAMILY SSF50447 202 315 6.03E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 PRINTS PR00315 GTP-binding elongation factor signature 102 113 6.5E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 PRINTS PR00315 GTP-binding elongation factor signature 139 148 6.5E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 PRINTS PR00315 GTP-binding elongation factor signature 86 96 6.5E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.5E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Gene3D G3DSA:2.40.30.10 318 409 1.3E-33 T 23-10-2018 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Gene3D G3DSA:3.40.50.300 2 202 8.0E-69 T 23-10-2018 A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 3 408 61.405 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L12_03440 e3f1abef2510649976e479e21796cf6e 409 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 194 9.1E-19 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 217 2.5E-93 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 Gene3D G3DSA:3.20.20.70 2 224 5.3E-110 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 Pfam PF01791 DeoC/LacD family aldolase 13 216 7.9E-22 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 SMART SM01133 6 219 3.2E-118 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 SUPERFAMILY SSF51569 4 220 2.51E-95 T 23-10-2018 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 PIRSF PIRSF001357 2 225 1.0E-92 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_04570 1eec9f988d0ffc6bb081ae75ce02528a 225 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 5 221 40.032 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 SUPERFAMILY SSF53474 358 611 3.05E-58 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 SUPERFAMILY SSF82171 14 350 1.01E-22 T 23-10-2018 A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 Pfam PF07676 WD40-like Beta Propeller Repeat 62 88 0.067 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 Gene3D G3DSA:2.120.10.30 7 203 1.3E-13 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 Gene3D G3DSA:3.40.50.1820 358 628 4.3E-86 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_04410 130e0b7301c7c1572c04f8353f22eb3e 629 Pfam PF00326 Prolyl oligopeptidase family 401 611 4.4E-54 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L12_04865 fea49f7a099234980b22e4236bc2d760 337 Gene3D G3DSA:3.40.50.10210 1 333 9.9E-125 T 23-10-2018 A3L12_04865 fea49f7a099234980b22e4236bc2d760 337 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 6.0E-98 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L12_04865 fea49f7a099234980b22e4236bc2d760 337 Hamap MF_01086 UPF0284 protein . 1 337 136.748 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L12_04865 fea49f7a099234980b22e4236bc2d760 337 SUPERFAMILY SSF52733 18 328 7.06E-42 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L12_04450 552f25323d83a9f266699400670a7965 424 SMART SM00729 138 355 7.1E-58 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_04450 552f25323d83a9f266699400670a7965 424 SUPERFAMILY SSF102114 128 355 3.53E-54 T 23-10-2018 A3L12_04450 552f25323d83a9f266699400670a7965 424 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 6.4E-22 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A3L12_04450 552f25323d83a9f266699400670a7965 424 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A3L12_04450 552f25323d83a9f266699400670a7965 424 Pfam PF01938 TRAM domain 367 424 1.5E-8 T 23-10-2018 IPR002792 TRAM domain A3L12_04450 552f25323d83a9f266699400670a7965 424 Gene3D G3DSA:3.80.30.20 136 369 1.6E-74 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L12_04450 552f25323d83a9f266699400670a7965 424 Pfam PF04055 Radical SAM superfamily 142 314 1.2E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_04450 552f25323d83a9f266699400670a7965 424 Gene3D G3DSA:3.40.50.12160 2 124 1.9E-25 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A3L12_04450 552f25323d83a9f266699400670a7965 424 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 3.3E-129 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A3L12_04450 552f25323d83a9f266699400670a7965 424 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 421 4.1E-137 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 Pfam PF13424 Tetratricopeptide repeat 92 165 8.2E-10 T 23-10-2018 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 Pfam PF13432 Tetratricopeptide repeat 178 237 1.2E-5 T 23-10-2018 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 SMART SM00028 174 207 32.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 SMART SM00028 93 126 0.006 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 SMART SM00028 134 167 52.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 SMART SM00028 211 244 400.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 SUPERFAMILY SSF48452 51 289 1.9E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_03010 4c0fcc908d82efb59163e16f4b624459 339 Gene3D G3DSA:1.25.40.10 52 312 1.3E-26 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 329 3.0E-28 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 Gene3D G3DSA:3.90.870.10 2 211 8.3E-86 T 23-10-2018 A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 Pfam PF01300 Telomere recombination 22 196 6.8E-60 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 207 1.0E-65 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 SUPERFAMILY SSF55821 8 209 3.97E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 PIRSF PIRSF004930 1 335 6.0E-128 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A3L12_06625 1ab4bd70acc9017f72cd163785398fcc 335 Gene3D G3DSA:3.40.50.11030 212 335 1.9E-37 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.26 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 SUPERFAMILY SSF55326 2 164 2.09E-39 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 SUPERFAMILY SSF56042 167 325 1.64E-42 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 Gene3D G3DSA:3.30.1330.10 2 165 2.9E-51 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 325 8.5E-24 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 Gene3D G3DSA:3.90.650.10 166 332 1.8E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 2.8E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_03125 292499a65bfa96ef5d3aac1f4f0c3e25 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 320 6.1E-122 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_01260 d35961f8c0a9f12e9dba827e9e73139f 246 Gene3D G3DSA:3.40.50.620 56 199 3.5E-13 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_01260 d35961f8c0a9f12e9dba827e9e73139f 246 PIRSF PIRSF006601 1 246 2.6E-92 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A3L12_01260 d35961f8c0a9f12e9dba827e9e73139f 246 SUPERFAMILY SSF52402 52 189 4.85E-17 T 23-10-2018 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 Gene3D G3DSA:3.40.430.10 150 347 2.2E-43 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 SUPERFAMILY SSF53927 3 147 4.89E-48 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 337 3.3E-95 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 91 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 Pfam PF01872 RibD C-terminal domain 150 334 9.8E-25 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 SUPERFAMILY SSF53597 150 341 2.66E-41 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 2.1E-24 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 Gene3D G3DSA:3.40.140.10 1 148 2.3E-53 T 23-10-2018 A3L12_03050 9691b4bbca55d308cea776205c5f5708 347 PIRSF PIRSF006769 1 345 8.2E-108 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 SMART SM00984 322 413 9.6E-35 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 Gene3D G3DSA:3.40.50.720 10 206 3.8E-72 T 23-10-2018 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 190 2.0E-50 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 408 6.3E-125 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 295 1.8E-23 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 PIRSF PIRSF000124 10 416 2.9E-81 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 PIRSF PIRSF500136 1 425 2.5E-140 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 SUPERFAMILY SSF52413 313 412 8.37E-25 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 SUPERFAMILY SSF48179 209 298 7.31E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 Gene3D G3DSA:3.40.50.720 240 428 8.8E-66 T 23-10-2018 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 412 6.0E-23 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_05635 9df31e9b6c0c391b7a4f01c0c9455ad6 428 SUPERFAMILY SSF51735 11 201 3.26E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.20.70.20 63 171 3.6E-6 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF55608 528 630 6.24E-19 T 23-10-2018 IPR027434 Homing endonuclease A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR00379 Intein signature 733 750 1.8E-8 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR00379 Intein signature 440 452 1.8E-8 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR00379 Intein signature 391 404 1.8E-8 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR00379 Intein signature 542 554 1.8E-8 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR00379 Intein signature 569 584 1.8E-8 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SMART SM00305 720 765 1.4E-5 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.10.28.10 526 639 8.6E-169 T 23-10-2018 IPR027434 Homing endonuclease A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF51998 759 1240 2.87E-140 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF55608 430 527 1.43E-38 T 23-10-2018 IPR027434 Homing endonuclease A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SMART SM00306 300 429 2.4E-18 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF03477 ATP cone domain 5 93 9.4E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF51998 234 302 3.66E-6 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF51294 302 760 2.16E-36 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 736 760 4.0E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF09061 Stirrup 637 719 5.5E-34 T 23-10-2018 IPR015146 Ribonucleotide reductase, stirrup GO:0016788 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF54786 637 719 2.31E-29 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.20.70.20 190 303 3.2E-19 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF14890 Intein splicing domain 309 759 6.4E-37 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 7.0E-27 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.30.160.90 640 719 8.6E-169 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF14528 LAGLIDADG-like domain 543 615 1.2E-10 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 760 1238 4.9E-201 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.10.28.10 439 525 8.6E-169 T 23-10-2018 IPR027434 Homing endonuclease A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR01183 Ribonucleotide reductase large chain signature 804 823 1.5E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR01183 Ribonucleotide reductase large chain signature 1082 1109 1.5E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR01183 Ribonucleotide reductase large chain signature 951 974 1.5E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR01183 Ribonucleotide reductase large chain signature 1017 1040 1.5E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 PRINTS PR01183 Ribonucleotide reductase large chain signature 989 1011 1.5E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 SUPERFAMILY SSF48168 9 154 2.88E-12 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:3.20.70.20 757 1244 1.6E-179 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Gene3D G3DSA:2.170.16.10 322 756 8.6E-169 T 23-10-2018 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF02867 Ribonucleotide reductase, barrel domain 760 1229 1.6E-221 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 302 403 7.0E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_02770 ce39db679befbbcde56b8a2a07f757df 1360 Pfam PF09062 PI-PfuI Endonuclease subdomain 430 527 9.5E-47 T 23-10-2018 IPR015147 PI-PfuI intein endonuclease, subdomain KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 PIRSF PIRSF001589 1 374 7.7E-59 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 PIRSF PIRSF001589 364 464 6.1E-21 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 Pfam PF00733 Asparagine synthase 226 358 3.3E-32 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 Pfam PF00733 Asparagine synthase 365 457 5.0E-22 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 SUPERFAMILY SSF52402 217 460 3.31E-59 T 23-10-2018 A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 Gene3D G3DSA:3.40.50.620 214 478 8.0E-75 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 SUPERFAMILY SSF56235 11 204 2.23E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 Pfam PF13537 Glutamine amidotransferase domain 61 179 5.8E-26 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L12_06640 08709cc57e2e990bd2f70df3cc76d55a 479 Gene3D G3DSA:3.60.20.10 2 213 2.2E-43 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_02045 d91269a09757ef881e2659fc6ba5603d 67 SMART SM00803 12 66 9.9E-4 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L12_02045 d91269a09757ef881e2659fc6ba5603d 67 SUPERFAMILY SSF47113 3 66 8.81E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_02045 d91269a09757ef881e2659fc6ba5603d 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 2.4E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L12_02045 d91269a09757ef881e2659fc6ba5603d 67 Gene3D G3DSA:1.10.20.10 1 67 3.9E-23 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_01565 d91269a09757ef881e2659fc6ba5603d 67 SMART SM00803 12 66 9.9E-4 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L12_01565 d91269a09757ef881e2659fc6ba5603d 67 SUPERFAMILY SSF47113 3 66 8.81E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_01565 d91269a09757ef881e2659fc6ba5603d 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 2.4E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L12_01565 d91269a09757ef881e2659fc6ba5603d 67 Gene3D G3DSA:1.10.20.10 1 67 3.9E-23 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 SMART SM00487 245 491 5.0E-10 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Pfam PF00176 SNF2 family N-terminal domain 268 503 3.3E-8 T 23-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Gene3D G3DSA:3.30.870.10 5 208 1.8E-27 T 23-10-2018 A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Pfam PF00271 Helicase conserved C-terminal domain 816 942 8.4E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 SMART SM00490 847 942 3.4E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 SUPERFAMILY SSF52540 420 988 2.48E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Gene3D G3DSA:3.40.50.300 772 973 2.3E-36 T 23-10-2018 A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Gene3D G3DSA:3.40.50.10810 248 560 3.4E-24 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 SUPERFAMILY SSF52540 248 506 1.45E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 SUPERFAMILY SSF56024 112 195 4.97E-7 T 23-10-2018 A3L12_07360 4b6db4f62f1680adf6bbffc01052c765 1259 Pfam PF13091 PLD-like domain 55 190 3.0E-15 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A3L12_05785 339d152ae22015804f9e787d55e8de92 440 SUPERFAMILY SSF50249 126 207 1.71E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_05785 339d152ae22015804f9e787d55e8de92 440 Gene3D G3DSA:2.40.50.360 119 243 6.5E-112 T 23-10-2018 A3L12_05785 339d152ae22015804f9e787d55e8de92 440 SUPERFAMILY SSF52540 35 430 6.32E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05785 339d152ae22015804f9e787d55e8de92 440 Gene3D G3DSA:1.10.8.60 354 438 3.3E-24 T 23-10-2018 A3L12_05785 339d152ae22015804f9e787d55e8de92 440 Pfam PF06068 TIP49 C-terminus 14 403 7.3E-160 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A3L12_05785 339d152ae22015804f9e787d55e8de92 440 Gene3D G3DSA:3.40.50.300 18 349 6.5E-112 T 23-10-2018 A3L12_05785 339d152ae22015804f9e787d55e8de92 440 SMART SM00382 62 353 3.6E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 SUPERFAMILY SSF56235 5 202 2.24E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 Gene3D G3DSA:3.60.20.10 2 203 4.7E-68 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 189 5.9E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 Pfam PF00227 Proteasome subunit 6 185 1.1E-54 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 34.903 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 PRINTS PR00141 Proteasome component signature 146 157 1.5E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 PRINTS PR00141 Proteasome component signature 15 30 1.5E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 PRINTS PR00141 Proteasome component signature 135 146 1.5E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_01055 8b7719540d08ed2dc5b376d97976f606 203 PRINTS PR00141 Proteasome component signature 171 182 1.5E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_06905 29305355a898d0ba4b453827ee990805 238 Gene3D G3DSA:1.10.340.30 40 153 3.4E-63 T 23-10-2018 A3L12_06905 29305355a898d0ba4b453827ee990805 238 Pfam PF00633 Helix-hairpin-helix motif 121 149 3.7E-7 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 SMART SM00478 57 207 2.4E-55 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 SUPERFAMILY SSF48150 29 228 1.05E-62 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 PIRSF PIRSF001435 20 231 8.0E-40 T 23-10-2018 A3L12_06905 29305355a898d0ba4b453827ee990805 238 ProSitePatterns PS01155 Endonuclease III family signature. 123 152 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 190 8.5E-18 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 Hamap MF_00942 Endonuclease III [nth]. 21 231 33.053 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A3L12_06905 29305355a898d0ba4b453827ee990805 238 SMART SM00525 208 228 1.2E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 Gene3D G3DSA:1.10.1670.10 38 225 3.4E-63 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L12_06905 29305355a898d0ba4b453827ee990805 238 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 SUPERFAMILY SSF53613 62 143 4.36E-15 T 23-10-2018 IPR029056 Ribokinase-like A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 SUPERFAMILY SSF64153 4 61 1.7E-15 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 Pfam PF01256 Carbohydrate kinase 64 125 1.8E-11 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 84 94 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 Pfam PF03853 YjeF-related protein N-terminus 22 61 5.4E-9 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 Gene3D G3DSA:3.40.50.10260 10 64 1.8E-12 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L12_08160 f718275e7af8875a8e4704334de6d3ca 149 Gene3D G3DSA:3.40.1190.20 65 146 1.6E-18 T 23-10-2018 IPR029056 Ribokinase-like A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Pfam PF02978 Signal peptide binding domain 328 425 2.3E-33 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SUPERFAMILY SSF47364 1 94 1.1E-22 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SUPERFAMILY SSF47446 297 429 9.94E-42 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 37.621 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SMART SM00963 2 87 2.4E-23 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SUPERFAMILY SSF52540 96 297 7.16E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Gene3D G3DSA:1.20.120.140 6 305 1.0E-119 T 23-10-2018 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SMART SM00962 100 295 2.1E-98 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 8.7E-74 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Gene3D G3DSA:1.10.260.30 312 435 2.3E-44 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 7.6E-19 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 SMART SM00382 99 300 6.8E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_00870 437e1e906fe6838b76e69c574499bed1 448 Gene3D G3DSA:3.40.50.300 91 284 1.0E-119 T 23-10-2018 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 1.8E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.154 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 SUPERFAMILY SSF52540 79 355 1.2E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 SUPERFAMILY SSF50615 5 67 3.45E-5 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 SUPERFAMILY SSF47917 362 452 5.23E-10 T 23-10-2018 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 PIRSF PIRSF039114 1 463 5.1E-254 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 2.2E-68 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 461 2.3E-263 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A3L12_02475 37fb152c50f0e198839bd42e4fdc5b5e 463 Gene3D G3DSA:3.40.50.12240 2 459 7.7E-195 T 23-10-2018 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 SUPERFAMILY SSF55979 3 117 8.22E-32 T 23-10-2018 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 112 5.2E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 SUPERFAMILY SSF55979 125 249 1.45E-29 T 23-10-2018 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.184 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 3.2E-10 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 6.4E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 1.5E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 1.5E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 1.5E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 1.5E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 1.5E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L12_07620 1846dedcae6dbfa2d632abfed12e2c9b 249 Gene3D G3DSA:3.70.10.10 2 242 9.6E-76 T 23-10-2018 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.74 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 1.1E-15 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 SUPERFAMILY SSF55174 52 96 3.01E-8 T 23-10-2018 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Gene3D G3DSA:3.10.290.40 1 118 1.8E-48 T 23-10-2018 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 SMART SM00363 44 107 4.4E-11 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Pfam PF01479 S4 domain 45 91 5.0E-14 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 1.0E-38 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Gene3D G3DSA:2.40.50.740 123 177 1.2E-16 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Pfam PF00900 Ribosomal family S4e 96 173 8.5E-22 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 PIRSF PIRSF002116 2 243 4.8E-99 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00655 e234dbb8f587aaee5e5fbb2eb95f9ae5 243 Gene3D G3DSA:2.30.30.30 179 243 3.6E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 1.3E-137 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 Gene3D G3DSA:3.40.50.280 3 126 1.9E-22 T 23-10-2018 A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 SUPERFAMILY SSF102114 153 376 1.16E-38 T 23-10-2018 A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 SMART SM00729 164 382 3.9E-45 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 Pfam PF02310 B12 binding domain 18 112 1.4E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 Gene3D G3DSA:3.80.30.20 163 388 3.5E-36 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L12_01570 0eee40b304fc5cf05c9dc9b1a84874fe 424 Pfam PF04055 Radical SAM superfamily 168 334 2.3E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_01385 f32efd404fff00b4c2f0c725f554fed2 167 SUPERFAMILY SSF54862 5 137 1.85E-20 T 23-10-2018 A3L12_01385 f32efd404fff00b4c2f0c725f554fed2 167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_01385 f32efd404fff00b4c2f0c725f554fed2 167 Pfam PF00037 4Fe-4S binding domain 67 88 3.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01385 f32efd404fff00b4c2f0c725f554fed2 167 Pfam PF12798 4Fe-4S binding domain 46 57 0.066 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01385 f32efd404fff00b4c2f0c725f554fed2 167 Gene3D G3DSA:3.30.70.20 36 106 5.7E-14 T 23-10-2018 A3L12_07930 cb9ea77821f7774d5a04746493ab5764 262 Pfam PF00005 ABC transporter 20 165 1.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07930 cb9ea77821f7774d5a04746493ab5764 262 SMART SM00382 28 222 4.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07930 cb9ea77821f7774d5a04746493ab5764 262 SUPERFAMILY SSF52540 3 228 1.33E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07930 cb9ea77821f7774d5a04746493ab5764 262 Gene3D G3DSA:3.40.50.300 1 245 7.2E-64 T 23-10-2018 A3L12_07930 cb9ea77821f7774d5a04746493ab5764 262 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_05405 dac3dad3887e7650873180a8d276ee77 179 SUPERFAMILY SSF52540 1 155 3.99E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05405 dac3dad3887e7650873180a8d276ee77 179 Hamap MF_00039 Putative adenylate kinase. 1 160 25.197 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_05405 dac3dad3887e7650873180a8d276ee77 179 Gene3D G3DSA:3.40.50.300 1 179 6.7E-57 T 23-10-2018 A3L12_05405 dac3dad3887e7650873180a8d276ee77 179 Pfam PF13238 AAA domain 3 116 4.2E-21 T 23-10-2018 A3L12_02970 d210d0f8d0ccaddf8d53323eaaeeada7 331 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 280 5.4E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_02970 d210d0f8d0ccaddf8d53323eaaeeada7 331 Pfam PF00483 Nucleotidyl transferase 3 234 8.3E-37 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L12_02970 d210d0f8d0ccaddf8d53323eaaeeada7 331 Gene3D G3DSA:2.160.10.10 240 330 3.4E-7 T 23-10-2018 A3L12_02970 d210d0f8d0ccaddf8d53323eaaeeada7 331 Gene3D G3DSA:3.90.550.10 1 239 5.9E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02970 d210d0f8d0ccaddf8d53323eaaeeada7 331 SUPERFAMILY SSF53448 1 286 2.82E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01615 dccc69eb68c6f645200e196a2c839230 433 Gene3D G3DSA:1.20.1250.20 230 429 4.7E-19 T 23-10-2018 A3L12_01615 dccc69eb68c6f645200e196a2c839230 433 SUPERFAMILY SSF103473 8 427 9.68E-41 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_01615 dccc69eb68c6f645200e196a2c839230 433 Gene3D G3DSA:1.20.1250.20 5 222 6.1E-13 T 23-10-2018 A3L12_01615 dccc69eb68c6f645200e196a2c839230 433 Pfam PF07690 Major Facilitator Superfamily 21 265 4.2E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 223 248 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 1.6E-15 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L12_03945 44c6925dc891952237133ae8e5a2c2b4 428 Pfam PF03600 Citrate transporter 18 368 7.0E-54 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L12_04345 1a5981fcbd689bba92e64c9113bfa3fa 145 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 133 2.9E-54 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A3L12_04345 1a5981fcbd689bba92e64c9113bfa3fa 145 Pfam PF14601 DNA_binding protein, TFX, C-term 52 131 1.2E-20 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A3L12_04345 1a5981fcbd689bba92e64c9113bfa3fa 145 SUPERFAMILY SSF89915 17 109 6.28E-24 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L12_04345 1a5981fcbd689bba92e64c9113bfa3fa 145 Gene3D G3DSA:3.30.1190.10 17 134 1.7E-34 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L12_04345 1a5981fcbd689bba92e64c9113bfa3fa 145 PIRSF PIRSF004932 3 144 1.3E-60 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:2.20.20.30 681 723 1.1E-6 T 23-10-2018 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SMART SM00437 916 1172 1.3E-93 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:1.10.460.10 825 1213 2.6E-143 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Pfam PF00270 DEAD/DEAH box helicase 88 222 3.8E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:3.40.50.300 546 629 2.3E-13 T 23-10-2018 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:3.40.50.300 320 497 8.9E-33 T 23-10-2018 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SUPERFAMILY SSF52540 43 241 1.44E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SUPERFAMILY SSF52540 326 625 6.84E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SMART SM00493 642 795 1.6E-42 T 23-10-2018 IPR006171 TOPRIM domain A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1218 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:1.10.290.10 926 1050 2.6E-143 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 64.554 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SMART SM00436 796 883 4.7E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SMART SM00382 98 333 0.0031 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 2.1E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 2.1E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 2.1E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 2.1E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 2.1E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:3.40.50.140 729 821 2.4E-20 T 23-10-2018 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Pfam PF01751 Toprim domain 644 805 2.0E-27 T 23-10-2018 IPR006171 TOPRIM domain A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Pfam PF01131 DNA topoisomerase 820 1209 1.3E-83 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SUPERFAMILY SSF56712 637 1218 6.8E-143 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:2.60.510.20 877 1117 2.6E-143 T 23-10-2018 A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 SMART SM00487 81 329 7.5E-20 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06350 b5d178cf93f3fc067b3b9f59c69a0152 1221 Gene3D G3DSA:3.40.50.300 64 319 3.4E-81 T 23-10-2018 A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 8.6E-86 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 Gene3D G3DSA:3.30.70.3130 4 96 1.1E-17 T 23-10-2018 A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 97 5.1E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 SUPERFAMILY SSF53335 22 306 1.81E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 4.5E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 4.5E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 4.5E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 4.5E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 4.5E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 Gene3D G3DSA:3.40.50.150 98 311 1.7E-66 T 23-10-2018 A3L12_07735 1f784bf0f5845e202795e8f3f6fcfe99 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 2.6E-47 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 SUPERFAMILY SSF52540 115 358 1.29E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Gene3D G3DSA:3.40.50.300 323 536 1.0E-52 T 23-10-2018 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 SUPERFAMILY SSF52540 264 510 4.82E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 7 112 1.9E-7 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Gene3D G3DSA:2.60.40.1120 550 632 1.6E-7 T 23-10-2018 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Pfam PF13620 Carboxypeptidase regulatory-like domain 550 614 4.3E-10 T 23-10-2018 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Gene3D G3DSA:3.40.50.300 134 322 1.6E-72 T 23-10-2018 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Pfam PF00271 Helicase conserved C-terminal domain 395 508 5.7E-6 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Pfam PF04851 Type III restriction enzyme, res subunit 151 306 6.5E-42 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 Gene3D G3DSA:3.90.1570.30 1 130 7.4E-50 T 23-10-2018 A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 SUPERFAMILY SSF49464 549 615 1.57E-9 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L12_08145 bceb55e07f1fb86c46a432fad63defd2 668 SMART SM00487 149 340 2.2E-20 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 355 4.1E-73 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 PIRSF PIRSF038945 32 379 7.3E-84 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 SUPERFAMILY SSF53686 2 365 1.24E-86 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 Gene3D G3DSA:3.40.50.1100 44 360 3.8E-105 T 23-10-2018 A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 Gene3D G3DSA:3.40.50.1100 93 188 3.8E-105 T 23-10-2018 A3L12_06455 930c0c9c983ea5c6ed16b4a1fc37d1af 382 TIGRFAM TIGR00260 thrC: threonine synthase 55 360 1.7E-57 T 23-10-2018 IPR004450 Threonine synthase-like A3L12_02195 7a6c056aef81ba429f46c2c45dff6225 332 Gene3D G3DSA:1.10.10.10 264 329 3.0E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_02195 7a6c056aef81ba429f46c2c45dff6225 332 SUPERFAMILY SSF46785 264 328 6.15E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_02195 7a6c056aef81ba429f46c2c45dff6225 332 Pfam PF04122 Putative cell wall binding repeat 2 112 190 7.2E-7 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L12_02195 7a6c056aef81ba429f46c2c45dff6225 332 Pfam PF01047 MarR family 275 315 3.2E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L12_05645 5ec7e8f325230ff7f336a3aed0d6cc26 420 Gene3D G3DSA:3.20.20.70 111 357 1.0E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_05645 5ec7e8f325230ff7f336a3aed0d6cc26 420 SUPERFAMILY SSF102114 110 334 1.96E-37 T 23-10-2018 A3L12_05645 5ec7e8f325230ff7f336a3aed0d6cc26 420 SMART SM00729 115 333 7.0E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_05645 5ec7e8f325230ff7f336a3aed0d6cc26 420 Pfam PF04055 Radical SAM superfamily 123 287 1.2E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_05810 aefcecbf761370e212e086332954f4d6 49 Gene3D G3DSA:2.20.28.30 1 49 1.0E-24 T 23-10-2018 A3L12_05810 aefcecbf761370e212e086332954f4d6 49 SMART SM00659 4 49 3.3E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_05810 aefcecbf761370e212e086332954f4d6 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.912 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_05810 aefcecbf761370e212e086332954f4d6 49 SUPERFAMILY SSF63393 4 48 4.18E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L12_05810 aefcecbf761370e212e086332954f4d6 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 1.6E-11 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 5.9E-27 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.9E-27 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 5.9E-27 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 5.9E-27 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 5.9E-27 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 Gene3D G3DSA:3.50.50.60 5 315 1.2E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 437 6.3E-180 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 293 2.1E-56 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 Gene3D G3DSA:3.50.50.60 321 442 8.8E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 1.4E-18 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 3.9E-21 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 3.9E-21 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 3.9E-21 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.9E-21 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 3.9E-21 T 23-10-2018 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 SUPERFAMILY SSF55424 321 439 6.01E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 Gene3D G3DSA:3.50.50.60 44 242 1.2E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01910 e6e13736c2c207c909d2ca02b8a75d00 442 SUPERFAMILY SSF51905 3 344 2.02E-49 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_06500 e4edfb32651bac14567636183cf84f61 287 Gene3D G3DSA:3.40.50.10890 128 190 3.8E-22 T 23-10-2018 A3L12_06500 e4edfb32651bac14567636183cf84f61 287 Gene3D G3DSA:3.60.15.10 50 127 3.8E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_06500 e4edfb32651bac14567636183cf84f61 287 SUPERFAMILY SSF56281 14 275 1.9E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 Gene3D G3DSA:3.40.640.10 35 280 5.3E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 Pfam PF00266 Aminotransferase class-V 45 370 9.6E-42 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 PIRSF PIRSF000524 17 384 1.4E-104 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 Gene3D G3DSA:3.90.1150.10 26 379 5.3E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 SUPERFAMILY SSF53383 22 382 4.26E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_00570 52fb1dd2c317afd19af82c9168daca6f 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A3L12_08010 7753f1c89c74c538d21f00d6b04ad685 282 SUPERFAMILY SSF48239 13 258 1.44E-15 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L12_08010 7753f1c89c74c538d21f00d6b04ad685 282 PIRSF PIRSF016175 7 282 2.2E-112 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A3L12_08010 7753f1c89c74c538d21f00d6b04ad685 282 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 244 278 0.14 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L12_08010 7753f1c89c74c538d21f00d6b04ad685 282 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 13 32 0.44 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 6 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 1.9E-28 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:1.10.274.100 491 671 9.1E-62 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:3.30.1490.180 354 418 1.9E-80 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 698 804 7.5E-30 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:1.20.120.1280 235 284 9.3E-12 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:1.20.120.1280 1 121 1.7E-31 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:1.10.132.30 672 813 2.7E-42 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:2.40.40.20 311 482 1.9E-80 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 SMART SM00663 211 515 1.5E-205 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 4.7E-107 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Gene3D G3DSA:2.20.25.410 850 900 1.7E-21 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 SUPERFAMILY SSF64484 4 886 0.0 T 23-10-2018 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 5.2E-36 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01715 7f53c29c037c0c79b3d5a52881ede408 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 2.8E-74 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00045 7f3b2b35e79e6c8d328e06f8b8321cc5 225 SUPERFAMILY SSF56529 13 218 5.63E-82 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L12_00045 7f3b2b35e79e6c8d328e06f8b8321cc5 225 Gene3D G3DSA:3.90.850.10 4 221 3.3E-91 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L12_00045 7f3b2b35e79e6c8d328e06f8b8321cc5 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 3.5E-69 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A3L12_06665 1ff4fc24552b4fe91da0ef4a1c6c7654 218 Pfam PF02811 PHP domain 7 118 1.3E-7 T 23-10-2018 IPR004013 PHP domain GO:0003824 A3L12_06665 1ff4fc24552b4fe91da0ef4a1c6c7654 218 SMART SM00481 6 78 7.8E-10 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A3L12_06665 1ff4fc24552b4fe91da0ef4a1c6c7654 218 SUPERFAMILY SSF89550 6 214 3.66E-37 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L12_06665 1ff4fc24552b4fe91da0ef4a1c6c7654 218 Gene3D G3DSA:3.20.20.140 2 217 1.3E-47 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 SUPERFAMILY SSF51905 5 347 1.62E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 299 4.9E-35 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 1.3E-23 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-23 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.3E-23 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.3E-23 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.3E-23 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.3E-16 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 2.3E-16 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.3E-16 T 23-10-2018 A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 Gene3D G3DSA:3.50.50.60 5 299 1.9E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04130 7421f4aa9a88adb531f79f4b6e50fcb9 416 Gene3D G3DSA:3.50.50.60 124 258 1.9E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_06695 6c60618981941125120e7d395a746166 224 Gene3D G3DSA:1.10.10.580 148 217 2.0E-30 T 23-10-2018 IPR023093 ScpA-like, C-terminal A3L12_06695 6c60618981941125120e7d395a746166 224 Pfam PF02616 Segregation and condensation protein ScpA 19 158 2.4E-12 T 23-10-2018 IPR003768 Segregation and condensation protein A A3L12_05620 f9d0162bdce798be6ae325d519272a44 94 Gene3D G3DSA:3.30.390.50 3 90 1.1E-25 T 23-10-2018 A3L12_05620 f9d0162bdce798be6ae325d519272a44 94 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 9 59 3.1E-6 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A3L12_05620 f9d0162bdce798be6ae325d519272a44 94 SUPERFAMILY SSF82649 7 88 1.78E-9 T 23-10-2018 A3L12_07120 444f13d4e9b1666cd6fc0082436b8d5b 319 SUPERFAMILY SSF47240 22 162 1.43E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_07120 444f13d4e9b1666cd6fc0082436b8d5b 319 Pfam PF02915 Rubrerythrin 25 159 3.5E-21 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07120 444f13d4e9b1666cd6fc0082436b8d5b 319 Pfam PF05763 Protein of unknown function (DUF835) 182 315 8.9E-25 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_07120 444f13d4e9b1666cd6fc0082436b8d5b 319 Gene3D G3DSA:1.20.1260.10 15 163 6.6E-32 T 23-10-2018 IPR012347 Ferritin-like A3L12_06075 8376089600de7cc4389e3c7110a97422 267 Gene3D G3DSA:3.30.70.580 1 103 1.5E-25 T 23-10-2018 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 SUPERFAMILY SSF55120 1 232 1.17E-63 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 Gene3D G3DSA:3.30.70.660 104 226 2.4E-24 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 222 7.2E-51 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 PIRSF PIRSF001430 1 243 1.9E-72 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 5.2E-20 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06075 8376089600de7cc4389e3c7110a97422 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 31.042 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_01440 38ba32df33837285385844f01de10621 341 SUPERFAMILY SSF53850 31 333 8.42E-50 T 23-10-2018 A3L12_01440 38ba32df33837285385844f01de10621 341 Gene3D G3DSA:3.40.190.10 34 334 2.9E-129 T 23-10-2018 A3L12_01440 38ba32df33837285385844f01de10621 341 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 33 303 1.7E-118 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 A3L12_01440 38ba32df33837285385844f01de10621 341 Pfam PF13531 Bacterial extracellular solute-binding protein 34 315 1.3E-36 T 23-10-2018 A3L12_01440 38ba32df33837285385844f01de10621 341 Gene3D G3DSA:3.40.190.10 119 285 2.9E-129 T 23-10-2018 A3L12_07480 5787caccb742a941b67e2d035de0262e 316 SUPERFAMILY SSF101960 64 315 7.85E-46 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L12_07480 5787caccb742a941b67e2d035de0262e 316 Pfam PF01458 Uncharacterized protein family (UPF0051) 95 312 2.5E-32 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L12_02965 65aae5ec74178f2178fbb6b77c9c98e0 528 Gene3D G3DSA:3.40.720.10 412 502 1.8E-12 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_02965 65aae5ec74178f2178fbb6b77c9c98e0 528 Gene3D G3DSA:3.40.720.10 2 273 9.4E-50 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_02965 65aae5ec74178f2178fbb6b77c9c98e0 528 SUPERFAMILY SSF53649 5 272 5.07E-37 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_02965 65aae5ec74178f2178fbb6b77c9c98e0 528 SUPERFAMILY SSF53649 352 472 3.99E-9 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_02965 65aae5ec74178f2178fbb6b77c9c98e0 528 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 7 422 2.0E-44 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 SUPERFAMILY SSF56059 103 332 2.53E-78 T 23-10-2018 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Gene3D G3DSA:3.30.470.20 89 332 1.7E-99 T 23-10-2018 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Pfam PF06973 Domain of unknown function (DUF1297) 157 332 1.1E-72 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Gene3D G3DSA:3.30.1490.20 116 176 1.7E-99 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 SUPERFAMILY SSF52440 2 99 5.66E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 3 333 48.914 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Pfam PF06849 Protein of unknown function (DUF1246) 5 118 2.1E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 PIRSF PIRSF004602 1 333 3.1E-131 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03165 58ac58787dc74b8d08d97100507119a1 333 Gene3D G3DSA:3.40.50.20 1 86 1.1E-29 T 23-10-2018 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 PIRSF PIRSF006487 1 398 6.0E-105 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Gene3D G3DSA:3.30.1360.120 8 255 5.8E-90 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 2.9E-96 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Gene3D G3DSA:3.30.70.1400 52 143 5.8E-90 T 23-10-2018 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 382 6.9E-24 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.243 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 5.8E-92 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 SUPERFAMILY SSF103025 2 308 2.51E-93 T 23-10-2018 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Gene3D G3DSA:4.10.1250.10 256 304 9.3E-8 T 23-10-2018 A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 SUPERFAMILY SSF101790 311 392 2.13E-24 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A3L12_04100 a34a64a8b4f92dc96c67faec185181e5 398 Gene3D G3DSA:2.40.30.110 310 383 3.8E-30 T 23-10-2018 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 SMART SM01193 7 135 5.3E-93 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 Hamap MF_00318 Enolase [eno]. 5 414 45.548 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PIRSF PIRSF001400 3 427 7.6E-194 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.5E-195 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 Gene3D G3DSA:3.30.390.10 2 127 3.7E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 Gene3D G3DSA:3.20.20.120 129 428 2.9E-131 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 SUPERFAMILY SSF54826 6 140 3.2E-56 T 23-10-2018 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 SUPERFAMILY SSF51604 139 428 1.83E-124 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 6.8E-129 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 SMART SM01192 140 428 1.4E-206 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 162 175 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 108 124 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 337 351 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 39 53 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 314 325 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 PRINTS PR00148 Enolase signature 366 383 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_04575 96e2ad26b8a85b07e9775722426c7559 430 Pfam PF03952 Enolase, N-terminal domain 7 135 3.2E-59 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_06140 a2509632af7a88577768452b22507a90 195 SMART SM00316 68 148 9.6E-10 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L12_06140 a2509632af7a88577768452b22507a90 195 Gene3D G3DSA:2.20.70.10 155 188 1.2E-16 T 23-10-2018 A3L12_06140 a2509632af7a88577768452b22507a90 195 Gene3D G3DSA:2.40.50.100 11 60 4.1E-17 T 23-10-2018 A3L12_06140 a2509632af7a88577768452b22507a90 195 SUPERFAMILY SSF50249 64 185 3.86E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_06140 a2509632af7a88577768452b22507a90 195 SUPERFAMILY SSF110324 11 63 5.23E-12 T 23-10-2018 A3L12_06140 a2509632af7a88577768452b22507a90 195 Gene3D G3DSA:2.40.50.140 66 154 2.7E-24 T 23-10-2018 A3L12_06140 a2509632af7a88577768452b22507a90 195 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 192 28.123 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A3L12_06140 a2509632af7a88577768452b22507a90 195 Pfam PF10447 Exosome component EXOSC1/CSL4 66 122 2.6E-5 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_06140 a2509632af7a88577768452b22507a90 195 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 1.0E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 Gene3D G3DSA:1.20.58.100 374 461 1.1E-18 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 SUPERFAMILY SSF51905 6 365 1.09E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 SUPERFAMILY SSF56425 205 309 4.64E-32 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 SUPERFAMILY SSF46977 387 453 9.42E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 176 5.2E-6 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 5.2E-6 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 5.2E-6 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 Gene3D G3DSA:3.90.700.10 213 303 2.2E-108 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 448 2.5E-152 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 9.8E-9 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.8E-9 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 9.8E-9 T 23-10-2018 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 424 449 2.3E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 Pfam PF00890 FAD binding domain 6 348 2.3E-65 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L12_03035 e6ccc0e0f31cb15811070769baf63ccf 466 Gene3D G3DSA:3.50.50.60 6 355 2.2E-108 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04925 b728966f3a454184596c4850b1f22f33 890 SUPERFAMILY SSF50677 187 335 4.19E-50 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 SUPERFAMILY SSF47323 588 825 1.85E-58 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Gene3D G3DSA:1.10.730.10 2 752 9.0E-239 T 23-10-2018 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Gene3D G3DSA:3.40.50.620 22 537 9.0E-239 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_04925 b728966f3a454184596c4850b1f22f33 890 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 867 3.3E-266 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 SUPERFAMILY SSF52374 3 581 2.29E-126 T 23-10-2018 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Gene3D G3DSA:3.90.740.10 170 337 9.0E-239 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Pfam PF08264 Anticodon-binding domain of tRNA 616 763 1.3E-34 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 795 28.805 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 5.0E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 PRINTS PR00986 Valyl-tRNA synthetase signature 488 506 5.0E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 5.0E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 5.0E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 5.0E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_04925 b728966f3a454184596c4850b1f22f33 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 572 2.8E-137 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 SUPERFAMILY SSF48163 323 523 2.09E-45 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 37.538 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Gene3D G3DSA:1.10.10.770 319 433 8.4E-37 T 23-10-2018 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Gene3D G3DSA:1.10.10.860 271 318 1.0E-22 T 23-10-2018 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 1.7E-155 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Gene3D G3DSA:3.40.50.620 4 270 1.0E-107 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Gene3D G3DSA:1.10.10.350 434 526 8.2E-24 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Gene3D G3DSA:2.30.30.300 170 213 1.0E-107 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 SUPERFAMILY SSF52374 3 319 7.68E-64 T 23-10-2018 A3L12_03705 77f22f4046604232ebc1436086e33b47 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 9.9E-134 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 Gene3D G3DSA:3.40.50.10860 36 181 5.2E-69 T 23-10-2018 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 Gene3D G3DSA:3.40.50.720 182 418 1.8E-98 T 23-10-2018 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 SUPERFAMILY SSF53223 3 184 4.8E-70 T 23-10-2018 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 9.2E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 9.2E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 9.2E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 9.2E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 SMART SM00839 184 415 9.6E-102 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 8.8E-78 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 1.3E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 SUPERFAMILY SSF51735 182 417 8.94E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01035 d3ed5f0f011f33059c87fff668e0f8bb 419 PIRSF PIRSF000185 1 418 3.6E-177 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A3L12_01905 ac51c779ad7de73ac8dc979eab42e4b4 378 Pfam PF01513 ATP-NAD kinase 4 377 1.0E-44 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L12_01905 ac51c779ad7de73ac8dc979eab42e4b4 378 SUPERFAMILY SSF111331 88 176 3.92E-7 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L12_01905 ac51c779ad7de73ac8dc979eab42e4b4 378 PIRSF PIRSF016907 1 378 8.2E-147 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A3L12_01905 ac51c779ad7de73ac8dc979eab42e4b4 378 Gene3D G3DSA:3.40.50.10330 80 173 4.2E-5 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L12_02255 431067418d323f60707d13c67e665b94 350 SUPERFAMILY SSF53901 11 169 1.49E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_02255 431067418d323f60707d13c67e665b94 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 349 1.2E-189 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L12_02255 431067418d323f60707d13c67e665b94 350 Hamap MF_01409 UPF0219 protein . 10 350 61.198 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L12_02255 431067418d323f60707d13c67e665b94 350 Gene3D G3DSA:3.40.47.10 9 349 3.2E-71 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_02255 431067418d323f60707d13c67e665b94 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 9.6E-12 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L12_02255 431067418d323f60707d13c67e665b94 350 SUPERFAMILY SSF53901 174 348 1.29E-46 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:3.10.28.10 479 579 2.8E-12 T 23-10-2018 IPR027434 Homing endonuclease A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SMART SM00305 635 682 1.5E-15 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:2.170.16.10 336 477 2.4E-34 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SUPERFAMILY SSF50249 9 248 1.52E-62 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF14551 MCM N-terminal domain 8 82 1.5E-12 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR00379 Intein signature 520 535 1.2E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR00379 Intein signature 420 433 1.2E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR00379 Intein signature 653 670 1.2E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR00379 Intein signature 495 507 1.2E-12 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF00493 MCM2/3/5 family 266 336 3.4E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF00493 MCM2/3/5 family 668 933 1.4E-106 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF17207 MCM OB domain 105 230 7.2E-35 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 773 785 2.1E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 800 808 2.1E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 749 762 2.1E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 320 335 2.1E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 721 735 2.1E-28 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SUPERFAMILY SSF52540 677 930 1.38E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:3.40.50.300 660 938 1.2E-110 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:3.40.50.300 263 335 1.5E-23 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SUPERFAMILY SSF55608 482 576 8.5E-12 T 23-10-2018 IPR027434 Homing endonuclease A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF14890 Intein splicing domain 343 676 3.6E-31 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SMART SM00350 101 935 2.4E-137 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 336 433 4.2E-20 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:1.10.10.10 939 1024 1.2E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SMART SM00306 334 457 9.4E-32 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Pfam PF14528 LAGLIDADG-like domain 494 565 1.6E-10 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:3.30.1640.10 1 100 7.5E-36 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 655 677 3.2E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 Gene3D G3DSA:2.20.28.10 134 180 1.9E-26 T 23-10-2018 A3L12_00520 8ad3b4bbe01dd3329193db2b12967936 1024 SUPERFAMILY SSF51294 335 676 7.72E-40 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 2 559 4.4E-173 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 35.451 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SUPERFAMILY SSF46955 5 81 3.94E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Gene3D G3DSA:3.50.40.10 81 278 6.7E-71 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SUPERFAMILY SSF56037 142 255 6.02E-5 T 23-10-2018 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SMART SM00874 280 348 1.6E-17 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Gene3D G3DSA:3.30.930.10 365 564 4.9E-51 T 23-10-2018 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Gene3D G3DSA:3.30.56.10 1 80 1.8E-22 T 23-10-2018 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SMART SM00873 100 259 9.5E-19 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Gene3D G3DSA:3.30.56.10 279 348 1.7E-24 T 23-10-2018 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Pfam PF01409 tRNA synthetases class II core domain (F) 329 555 1.6E-6 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 1.2E-11 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SUPERFAMILY SSF55681 345 562 1.29E-47 T 23-10-2018 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 Pfam PF03483 B3/4 domain 120 244 1.8E-15 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L12_06070 92d812d8b213f8ccd0dbce40835cadcb 568 SUPERFAMILY SSF46955 281 352 2.66E-15 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L12_06720 e16aa84e42eafb182bbeaccaedba9ed4 128 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 5 127 1.8E-63 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Gene3D G3DSA:2.60.40.10 571 661 8.3E-30 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Gene3D G3DSA:2.60.40.10 1749 1835 5.3E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 283 326 1.2E-8 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 460 504 4.6E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 306 347 5.9E-12 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 260 303 8.0E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 239 280 5.8E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 414 457 1.4E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SUPERFAMILY SSF51126 144 380 1.82E-44 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SUPERFAMILY SSF51126 347 560 1.29E-17 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Gene3D G3DSA:2.160.20.10 155 283 8.6E-24 T 23-10-2018 IPR012334 Pectin lyase fold A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Gene3D G3DSA:2.160.20.10 294 382 1.1E-9 T 23-10-2018 IPR012334 Pectin lyase fold A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00089 579 662 3.3E-31 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00722 177 333 9.6E-6 T 23-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00722 408 553 24.0 T 23-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Gene3D G3DSA:2.160.20.10 383 567 1.7E-14 T 23-10-2018 IPR012334 Pectin lyase fold A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 420 442 0.67 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 289 311 29.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 1706 1744 4100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 398 419 1100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 312 334 6.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 335 354 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 443 465 2.1 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 1068 1104 5300.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 218 243 480.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 466 488 7.4 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 266 288 7.6 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SMART SM00710 244 265 0.18 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Pfam PF13229 Right handed beta helix region 239 374 3.6E-20 T 23-10-2018 IPR039448 Right handed beta helix domain A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Pfam PF05048 Periplasmic copper-binding protein (NosD) 391 570 9.0E-45 T 23-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 Pfam PF00801 PKD domain 586 651 2.9E-18 T 23-10-2018 IPR000601 PKD domain A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SUPERFAMILY SSF49299 575 661 1.44E-25 T 23-10-2018 IPR035986 PKD domain superfamily A3L12_01145 cbeb9cf360bbf10a465f8ed17d7d766d 2054 SUPERFAMILY SSF49464 60 128 5.89E-7 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 Gene3D G3DSA:3.30.230.70 1 268 7.8E-88 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 1.8E-29 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 SUPERFAMILY SSF54211 10 212 2.18E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 Pfam PF03725 3' exoribonuclease family, domain 2 189 252 6.7E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 SUPERFAMILY SSF55666 184 266 7.43E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00465 7db64f2ef4c27dd48ea9998d3dea93a8 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 45.141 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A3L12_02380 70108b19126dfc80b2dbb74f74b2a2fb 251 SUPERFAMILY SSF102705 2 246 1.15E-68 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A3L12_02380 70108b19126dfc80b2dbb74f74b2a2fb 251 Gene3D G3DSA:3.40.1390.30 97 222 4.9E-76 T 23-10-2018 A3L12_02380 70108b19126dfc80b2dbb74f74b2a2fb 251 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 249 1.7E-59 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L12_02380 70108b19126dfc80b2dbb74f74b2a2fb 251 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 238 2.9E-56 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L12_02380 70108b19126dfc80b2dbb74f74b2a2fb 251 Gene3D G3DSA:3.40.1390.30 7 239 4.9E-76 T 23-10-2018 A3L12_01130 5582182241d28dfaa78618f9c11dd17c 100 Pfam PF04242 Protein of unknown function (DUF424) 7 97 7.1E-32 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A3L12_01130 5582182241d28dfaa78618f9c11dd17c 100 Gene3D G3DSA:3.30.1860.10 1 97 7.5E-34 T 23-10-2018 A3L12_02870 e5114ab3e735890d0137243640e93706 174 Gene3D G3DSA:3.40.50.300 1 174 5.6E-61 T 23-10-2018 A3L12_02870 e5114ab3e735890d0137243640e93706 174 Pfam PF01583 Adenylylsulphate kinase 3 153 2.2E-59 T 23-10-2018 A3L12_02870 e5114ab3e735890d0137243640e93706 174 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 2 164 2.1E-65 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L12_02870 e5114ab3e735890d0137243640e93706 174 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 1 171 36.615 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L12_02870 e5114ab3e735890d0137243640e93706 174 SUPERFAMILY SSF52540 2 170 8.52E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 Gene3D G3DSA:3.30.479.30 51 182 9.4E-51 T 23-10-2018 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 Pfam PF01145 SPFH domain / Band 7 family 27 197 7.3E-39 T 23-10-2018 IPR001107 Band 7 domain A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 156 174 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 200 223 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 112 129 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 30 52 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 175 196 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 132 155 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 PRINTS PR00721 Stomatin signature 77 98 4.8E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 SMART SM00244 23 180 1.5E-68 T 23-10-2018 IPR001107 Band 7 domain A3L12_06740 d1da2e687e544c594060708dbcc6e6ed 270 SUPERFAMILY SSF117892 54 187 1.7E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L12_06245 8e74961d76fd73475569896cb066eefc 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 525 5.2E-249 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L12_06245 8e74961d76fd73475569896cb066eefc 533 SUPERFAMILY SSF52540 3 265 2.15E-119 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06245 8e74961d76fd73475569896cb066eefc 533 Gene3D G3DSA:3.40.50.880 284 532 5.2E-105 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_06245 8e74961d76fd73475569896cb066eefc 533 Gene3D G3DSA:3.40.50.300 1 283 6.7E-137 T 23-10-2018 A3L12_06245 8e74961d76fd73475569896cb066eefc 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 2.3E-56 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L12_06245 8e74961d76fd73475569896cb066eefc 533 Pfam PF06418 CTP synthase N-terminus 3 264 1.9E-125 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L12_06245 8e74961d76fd73475569896cb066eefc 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 52.591 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L12_06245 8e74961d76fd73475569896cb066eefc 533 SUPERFAMILY SSF52317 288 528 1.07E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02245 457d402852b9f95a156ad5d320520399 134 Gene3D G3DSA:1.10.12.20 3 51 2.4E-6 T 23-10-2018 A3L12_02245 457d402852b9f95a156ad5d320520399 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 48 112 8.2E-23 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A3L12_02245 457d402852b9f95a156ad5d320520399 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 4.9E-11 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A3L12_02245 457d402852b9f95a156ad5d320520399 134 SUPERFAMILY SSF50249 7 116 2.4E-34 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 Pfam PF02769 AIR synthase related protein, C-terminal domain 143 287 4.0E-7 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 PIRSF PIRSF005303 2 304 1.7E-87 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 SUPERFAMILY SSF56042 136 291 4.78E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 Gene3D G3DSA:3.30.1330.10 1 137 1.5E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 304 9.6E-84 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 Gene3D G3DSA:3.90.650.10 138 304 3.2E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 SUPERFAMILY SSF55326 7 133 2.09E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 Pfam PF00586 AIR synthase related protein, N-terminal domain 23 132 2.9E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_05945 12c6302e6d7abfafa4c71f3e0066785f 312 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 304 26.825 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 450 4.6E-185 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 289 301 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 481 79.908 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 PIRSF PIRSF000130 3 482 2.2E-191 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 Gene3D G3DSA:3.20.20.70 4 481 1.0E-193 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 SMART SM00116 100 147 7.9E-10 T 23-10-2018 IPR000644 CBS domain A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 SMART SM00116 157 205 3.8E-14 T 23-10-2018 IPR000644 CBS domain A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 SMART SM01240 13 468 1.9E-254 T 23-10-2018 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 SUPERFAMILY SSF51412 5 479 2.22E-124 T 23-10-2018 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 468 1.0E-150 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 SUPERFAMILY SSF54631 98 201 1.43E-31 T 23-10-2018 A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 Pfam PF00571 CBS domain 150 203 3.8E-18 T 23-10-2018 IPR000644 CBS domain A3L12_03170 d867a2e00153302fdb9b9a793b49edd0 483 Pfam PF00571 CBS domain 100 143 3.8E-11 T 23-10-2018 IPR000644 CBS domain A3L12_01455 34cde92f7bf6dcc19b03709f191a3bf2 134 PIRSF PIRSF004681 1 134 1.5E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_01455 34cde92f7bf6dcc19b03709f191a3bf2 134 SUPERFAMILY SSF111038 3 131 2.22E-41 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L12_01455 34cde92f7bf6dcc19b03709f191a3bf2 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 131 1.1E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_01455 34cde92f7bf6dcc19b03709f191a3bf2 134 Gene3D G3DSA:2.60.120.460 1 133 9.8E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L12_01455 34cde92f7bf6dcc19b03709f191a3bf2 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 133 8.9E-41 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_03445 06485f25095826575c4afa0ae761251d 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03445 06485f25095826575c4afa0ae761251d 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.673 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L12_03445 06485f25095826575c4afa0ae761251d 125 SMART SM01405 4 124 1.2E-49 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03445 06485f25095826575c4afa0ae761251d 125 Pfam PF01092 Ribosomal protein S6e 4 124 9.5E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06195 3f3028198141ab1cfae9b9597cda75c5 284 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_06195 3f3028198141ab1cfae9b9597cda75c5 284 Gene3D G3DSA:3.40.50.300 2 277 1.9E-71 T 23-10-2018 A3L12_06195 3f3028198141ab1cfae9b9597cda75c5 284 Pfam PF00005 ABC transporter 21 178 6.3E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06195 3f3028198141ab1cfae9b9597cda75c5 284 SUPERFAMILY SSF52540 3 239 4.78E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06195 3f3028198141ab1cfae9b9597cda75c5 284 SMART SM00382 30 227 9.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 SMART SM00316 10 83 2.1E-23 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 3.2E-22 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 SUPERFAMILY SSF116742 85 174 1.22E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Pfam PF00575 S1 RNA binding domain 9 83 4.1E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 SUPERFAMILY SSF110993 176 260 6.67E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Gene3D G3DSA:1.10.150.190 86 171 6.3E-33 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Gene3D G3DSA:2.40.50.140 3 85 2.3E-31 T 23-10-2018 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 SUPERFAMILY SSF50249 7 87 5.15E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Gene3D G3DSA:3.30.70.1130 173 262 2.4E-31 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L12_01785 a844c5b56e2e449dc7c6e509b7a3853b 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.718 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 SUPERFAMILY SSF100950 77 233 7.44E-32 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 Gene3D G3DSA:1.10.10.10 1 56 6.4E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 SMART SM00420 6 58 6.8E-21 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.5E-8 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.5E-8 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 23-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 SMART SM01134 73 232 9.0E-69 T 23-10-2018 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.5E-19 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.7E-52 T 23-10-2018 IPR014036 DeoR C-terminal sensor domain A3L12_04800 ad03b95aaab9387b25e87e38ee6694c2 256 SUPERFAMILY SSF46785 4 69 2.62E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 SUPERFAMILY SSF47648 86 153 1.31E-15 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Gene3D G3DSA:3.90.1170.30 413 493 1.6E-28 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.069 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 SUPERFAMILY SSF52418 155 404 5.36E-68 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 1.3E-238 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 4.2E-15 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 PIRSF PIRSF000478 84 502 2.6E-123 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 1.1E-226 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Gene3D G3DSA:1.20.970.10 84 151 4.2E-24 T 23-10-2018 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Gene3D G3DSA:2.40.40.20 1 83 1.3E-34 T 23-10-2018 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 2.3E-14 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 6.8E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 Gene3D G3DSA:3.40.1030.10 152 412 2.0E-100 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 SUPERFAMILY SSF54680 412 495 1.57E-18 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_06725 1d434fe155d8d6f040083ef253fb9204 503 SMART SM00941 424 491 3.9E-24 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 SMART SM01130 1 289 5.0E-99 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 PIRSF PIRSF001365 1 291 6.0E-87 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 SUPERFAMILY SSF51569 3 290 1.05E-87 T 23-10-2018 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 6.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 6.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 6.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 6.9E-21 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 Gene3D G3DSA:3.20.20.70 1 290 4.3E-95 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 4.7E-68 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 287 3.4E-63 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L12_07105 9c4454f65ede11f271eaff1bf5ec35f1 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 162 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 Gene3D G3DSA:3.50.50.60 237 367 4.6E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 1.2E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 SUPERFAMILY SSF54292 17 98 1.48E-19 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 1.5E-26 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 1.5E-26 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 1.5E-26 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 1.5E-26 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 1.5E-26 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 1.1E-27 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 SUPERFAMILY SSF51905 97 433 8.98E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 3.7E-21 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 3.7E-21 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 3.7E-21 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 3.7E-21 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 3.7E-21 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 Gene3D G3DSA:3.10.20.440 6 99 2.5E-31 T 23-10-2018 A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 Gene3D G3DSA:3.50.50.60 118 451 4.6E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01380 dafb97ecc5cad579ee3c2ec811a8b6b1 478 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 Gene3D G3DSA:1.10.3270.10 1 74 1.6E-5 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 SUPERFAMILY SSF56542 4 398 7.32E-91 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 Gene3D G3DSA:3.90.770.10 75 395 1.8E-132 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 408 8.3E-166 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 275 301 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 1.5E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 SUPERFAMILY SSF55035 129 244 1.83E-40 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 Gene3D G3DSA:3.30.70.420 129 244 1.8E-132 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_06050 9a3aa36e48f1f3993711cbc91e799597 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 7.2E-138 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 SUPERFAMILY SSF81573 22 82 4.18E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 6.2E-35 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 14.868 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 SUPERFAMILY SSF160527 82 203 3.27E-23 T 23-10-2018 A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 Gene3D G3DSA:1.20.5.620 18 98 2.4E-23 T 23-10-2018 A3L12_02455 c614ee4b27b2c123652624efc02e9c77 203 Gene3D G3DSA:3.30.2320.30 100 203 1.0E-20 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1117 9.9E-32 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 6.7E-41 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 1.0E-18 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 SUPERFAMILY SSF64484 12 1119 0.0 T 23-10-2018 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:3.90.1110.10 177 335 3.3E-58 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:2.40.270.10 653 1011 6.5E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 6.8E-10 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 3.6E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:2.40.50.150 683 874 6.5E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:3.90.1100.10 336 506 1.4E-55 T 23-10-2018 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 9.3E-42 T 23-10-2018 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Gene3D G3DSA:3.90.1100.10 21 176 1.6E-12 T 23-10-2018 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 4.1E-133 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01710 3501a2f0e9e94dca52cc5caaf2f6118b 1122 Pfam PF04563 RNA polymerase beta subunit 29 380 3.4E-53 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 SMART SM00344 4 105 2.0E-8 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 SUPERFAMILY SSF46785 3 58 4.82E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 Gene3D G3DSA:1.10.10.10 1 56 4.5E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 Gene3D G3DSA:3.30.70.920 57 160 3.4E-32 T 23-10-2018 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 1.0E-13 T 23-10-2018 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.3E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.3E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05005 459836d2cf4f2691c79ca5e626be5ab7 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.3E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05475 66aaa014f421859069c7253bf721175d 295 Pfam PF00970 Oxidoreductase FAD-binding domain 38 114 1.4E-7 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L12_05475 66aaa014f421859069c7253bf721175d 295 Gene3D G3DSA:2.40.30.10 16 115 5.5E-19 T 23-10-2018 A3L12_05475 66aaa014f421859069c7253bf721175d 295 PIRSF PIRSF006816 17 294 9.2E-81 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L12_05475 66aaa014f421859069c7253bf721175d 295 Pfam PF00175 Oxidoreductase NAD-binding domain 128 232 2.2E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L12_05475 66aaa014f421859069c7253bf721175d 295 Gene3D G3DSA:3.40.50.80 118 249 5.0E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_05475 66aaa014f421859069c7253bf721175d 295 SUPERFAMILY SSF52343 111 286 3.8E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_05475 66aaa014f421859069c7253bf721175d 295 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 251 287 9.0E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L12_05475 66aaa014f421859069c7253bf721175d 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 127 146 1.6E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L12_05475 66aaa014f421859069c7253bf721175d 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 53 65 1.6E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L12_05475 66aaa014f421859069c7253bf721175d 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 219 227 1.6E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L12_05475 66aaa014f421859069c7253bf721175d 295 Gene3D G3DSA:2.10.240.10 251 288 2.3E-7 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L12_05475 66aaa014f421859069c7253bf721175d 295 SUPERFAMILY SSF63380 15 119 1.68E-23 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 Gene3D G3DSA:3.30.1250.10 8 87 1.8E-30 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 Pfam PF09377 SBDS protein C-terminal domain 102 200 1.2E-15 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 SUPERFAMILY SSF89895 4 87 3.14E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 Gene3D G3DSA:1.10.10.900 88 162 1.3E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 Gene3D G3DSA:3.30.70.240 163 235 1.3E-27 T 23-10-2018 A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 SUPERFAMILY SSF109728 88 161 5.62E-24 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 8.7E-25 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 SUPERFAMILY SSF54980 157 228 4.32E-21 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L12_00450 d54f7f6fc5677bf7fd5b9b2fffa45c3c 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 1.1E-86 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 A3L12_06020 5ed3f51b041ae0a13ba6beee9925458c 120 Gene3D G3DSA:1.10.150.80 55 120 3.3E-25 T 23-10-2018 A3L12_06020 5ed3f51b041ae0a13ba6beee9925458c 120 SUPERFAMILY SSF47819 1 115 9.59E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A3L12_06020 5ed3f51b041ae0a13ba6beee9925458c 120 PIRSF PIRSF005053 1 120 1.2E-30 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A3L12_06020 5ed3f51b041ae0a13ba6beee9925458c 120 Gene3D G3DSA:1.10.287.420 1 54 7.2E-34 T 23-10-2018 A3L12_06020 5ed3f51b041ae0a13ba6beee9925458c 120 Pfam PF03874 RNA polymerase Rpb4 11 118 4.0E-6 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 Pfam PF00574 Clp protease 53 190 2.6E-8 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 Pfam PF01957 NfeD-like C-terminal, partner-binding 293 439 6.4E-37 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 Gene3D G3DSA:2.40.50.140 376 445 7.1E-25 T 23-10-2018 A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 Gene3D G3DSA:3.90.226.10 20 244 6.6E-66 T 23-10-2018 A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 SUPERFAMILY SSF141322 371 439 1.07E-16 T 23-10-2018 A3L12_06745 78d9f2dd61790494e2203c3c8182ae33 445 SUPERFAMILY SSF52096 9 189 4.61E-30 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 Pfam PF13343 Bacterial extracellular solute-binding protein 77 300 1.4E-30 T 23-10-2018 A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 SUPERFAMILY SSF53850 24 332 1.68E-79 T 23-10-2018 A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 Gene3D G3DSA:3.40.190.10 30 306 2.3E-115 T 23-10-2018 A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 Gene3D G3DSA:3.40.190.10 131 331 2.3E-115 T 23-10-2018 A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 4.8E-97 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 378 9.0E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L12_07040 7f26f57a2c069bcd9c7f3810106cba72 378 PIRSF PIRSF002825 1 335 1.3E-52 T 23-10-2018 IPR026045 Ferric binding protein A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.565 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Pfam PF00679 Elongation factor G C-terminus 621 706 4.9E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SUPERFAMILY SSF54211 463 623 2.02E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 4.9E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SUPERFAMILY SSF50447 259 375 2.75E-32 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SUPERFAMILY SSF52540 10 261 4.6E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Gene3D G3DSA:3.30.70.240 466 718 1.9E-73 T 23-10-2018 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Gene3D G3DSA:2.40.30.10 259 386 2.2E-26 T 23-10-2018 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SUPERFAMILY SSF54980 624 718 7.19E-24 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SMART SM00838 621 708 1.1E-43 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Pfam PF14492 Elongation Factor G, domain II 387 459 6.2E-26 T 23-10-2018 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Gene3D G3DSA:3.40.50.300 7 222 6.9E-73 T 23-10-2018 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 9.0E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Pfam PF03764 Elongation factor G, domain IV 513 618 4.0E-26 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SUPERFAMILY SSF54980 388 463 4.32E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Gene3D G3DSA:3.30.70.870 388 465 4.9E-27 T 23-10-2018 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 SMART SM00889 505 619 1.5E-18 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 Gene3D G3DSA:3.30.230.10 472 720 1.9E-73 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_07870 abdb271bfd9179b3811d55703a9279ae 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 2.8E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 136 23.577 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 15 131 7.9E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 Gene3D G3DSA:3.30.420.80 3 139 1.4E-64 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 SUPERFAMILY SSF53137 11 137 4.9E-39 T 23-10-2018 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 PIRSF PIRSF002131 1 138 2.1E-35 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L12_00765 98f727dfb9e70336107a7a34d93faafc 139 Pfam PF00411 Ribosomal protein S11 17 135 1.7E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L12_07175 84dd245ca840674e2a78d7a8eab6f9c4 180 Gene3D G3DSA:3.40.50.300 3 176 1.1E-38 T 23-10-2018 A3L12_07175 84dd245ca840674e2a78d7a8eab6f9c4 180 SMART SM00382 1 178 5.7E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07175 84dd245ca840674e2a78d7a8eab6f9c4 180 SUPERFAMILY SSF52540 5 153 6.68E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07175 84dd245ca840674e2a78d7a8eab6f9c4 180 Pfam PF03266 NTPase 4 167 1.5E-50 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L12_07175 84dd245ca840674e2a78d7a8eab6f9c4 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 28.545 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 Pfam PF07705 CARDB 445 542 2.1E-19 T 23-10-2018 IPR011635 CARDB domain A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 Gene3D G3DSA:2.60.40.10 428 549 2.0E-32 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 Gene3D G3DSA:2.60.40.1190 23 233 2.3E-5 T 23-10-2018 A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 Gene3D G3DSA:2.60.40.1190 234 411 2.1E-6 T 23-10-2018 A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 SUPERFAMILY SSF49344 233 428 1.41E-11 T 23-10-2018 A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 SUPERFAMILY SSF49344 931 1097 3.02E-12 T 23-10-2018 A3L12_00220 1b2d341f3b1170fe9f5c779271bae511 1138 SUPERFAMILY SSF49344 24 214 3.92E-11 T 23-10-2018 A3L12_06585 308fedb6990ed062014b6ff614cfe41c 108 Pfam PF05239 PRC-barrel domain 3 82 1.8E-13 T 23-10-2018 IPR027275 PRC-barrel domain A3L12_06585 308fedb6990ed062014b6ff614cfe41c 108 Gene3D G3DSA:2.30.30.240 3 81 8.9E-6 T 23-10-2018 A3L12_06585 308fedb6990ed062014b6ff614cfe41c 108 SUPERFAMILY SSF50346 4 79 1.7E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L12_07425 39486134e6ff266ff7b98b7dde9b98e2 188 Gene3D G3DSA:3.40.50.360 1 188 7.1E-39 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L12_07425 39486134e6ff266ff7b98b7dde9b98e2 188 Pfam PF03358 NADPH-dependent FMN reductase 1 135 1.3E-27 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A3L12_07425 39486134e6ff266ff7b98b7dde9b98e2 188 SUPERFAMILY SSF52218 1 168 1.45E-32 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L12_07490 fc9a4079d8f198dc2cae438f078260ee 137 SUPERFAMILY SSF82784 5 124 2.75E-27 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L12_07490 fc9a4079d8f198dc2cae438f078260ee 137 Pfam PF02566 OsmC-like protein 35 128 1.8E-18 T 23-10-2018 IPR003718 OsmC/Ohr family A3L12_07490 fc9a4079d8f198dc2cae438f078260ee 137 Gene3D G3DSA:3.30.300.20 1 122 7.8E-25 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_06295 98b329cde6fbaecff03d006663521a12 438 SUPERFAMILY SSF50249 1 101 9.71E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_06295 98b329cde6fbaecff03d006663521a12 438 Gene3D G3DSA:2.40.50.140 1 107 1.2E-26 T 23-10-2018 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 Gene3D G3DSA:3.30.930.10 108 438 1.8E-121 T 23-10-2018 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 4.2E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 4.2E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 4.2E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 4.2E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 2.1E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 3.0E-181 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 SUPERFAMILY SSF55681 96 437 1.03E-100 T 23-10-2018 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.69 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_06295 98b329cde6fbaecff03d006663521a12 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 9.1E-94 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 SMART SM00382 28 213 3.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 Gene3D G3DSA:2.40.50.100 239 286 4.2E-9 T 23-10-2018 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 Gene3D G3DSA:3.40.50.300 1 238 1.6E-78 T 23-10-2018 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 Gene3D G3DSA:2.40.50.140 287 350 1.4E-32 T 23-10-2018 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 Pfam PF00005 ABC transporter 20 161 2.2E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 Pfam PF08402 TOBE domain 280 357 5.2E-8 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 SUPERFAMILY SSF50331 237 365 2.92E-26 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L12_01490 11e3a11eb3672d71547a3e14d2f7aaae 366 SUPERFAMILY SSF52540 4 243 1.58E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Pfam PF01568 Molydopterin dinucleotide binding domain 537 631 4.4E-18 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 9 52 7.7E-6 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 SMART SM00926 4 58 1.1E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Gene3D G3DSA:3.40.228.10 138 510 6.1E-121 T 23-10-2018 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 SUPERFAMILY SSF53706 7 524 5.37E-134 T 23-10-2018 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Gene3D G3DSA:2.40.40.20 525 644 2.8E-24 T 23-10-2018 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 SUPERFAMILY SSF50692 529 641 2.07E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Pfam PF00384 Molybdopterin oxidoreductase 61 433 3.0E-44 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Gene3D G3DSA:3.40.50.740 72 455 6.1E-121 T 23-10-2018 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Gene3D G3DSA:2.20.25.90 2 63 1.1E-10 T 23-10-2018 A3L12_03790 38c87d655947b1e9bc997e0324fd5799 644 Gene3D G3DSA:3.30.2070.10 412 491 6.1E-121 T 23-10-2018 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Pfam PF01472 PUA domain 251 323 9.0E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Gene3D G3DSA:2.30.130.70 23 332 2.4E-147 T 23-10-2018 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 SUPERFAMILY SSF88697 249 332 9.39E-24 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 2.4E-23 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.756 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 17 334 6.4E-136 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 239 320 1.4E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 SMART SM01136 4 63 1.8E-23 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 6.7E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Gene3D G3DSA:3.30.2350.10 40 243 2.4E-147 T 23-10-2018 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 SUPERFAMILY SSF55120 19 247 4.32E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 119 2.4E-15 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 120 180 1.1E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L12_00740 202d43639528be10ff9162e9f44b5f04 334 SMART SM00359 251 325 6.8E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 SUPERFAMILY SSF53774 88 436 5.1E-119 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 SUPERFAMILY SSF141300 4 73 3.53E-18 T 23-10-2018 IPR037222 GatD, N-terminal A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 Gene3D G3DSA:2.30.30.520 2 79 2.2E-22 T 23-10-2018 IPR037222 GatD, N-terminal A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 93 429 7.3E-145 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 4.7E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 4.7E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 4.7E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 48.803 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 Gene3D G3DSA:3.40.50.40 302 439 3.2E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 2.2E-195 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 Pfam PF00710 Asparaginase, N-terminal 95 288 3.4E-63 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 SMART SM00870 94 417 5.7E-153 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 PIRSF PIRSF500175 13 437 3.5E-189 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 PIRSF PIRSF001220 90 428 2.2E-109 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 Gene3D G3DSA:3.40.50.1170 81 301 1.1E-86 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L12_06040 723b80cf081cbc8d055b2055b6925d08 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L12_01720 3cccb853ee2e401523dd3df28950f197 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 383 8.0E-151 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01720 3cccb853ee2e401523dd3df28950f197 391 SUPERFAMILY SSF64484 32 385 1.56E-104 T 23-10-2018 A3L12_01720 3cccb853ee2e401523dd3df28950f197 391 Gene3D G3DSA:1.10.150.390 333 378 2.1E-23 T 23-10-2018 A3L12_01720 3cccb853ee2e401523dd3df28950f197 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 29 332 2.2E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_01720 3cccb853ee2e401523dd3df28950f197 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.15 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 SUPERFAMILY SSF63380 4 91 2.51E-12 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 218 226 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 SUPERFAMILY SSF52343 116 249 3.74E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 Gene3D G3DSA:3.40.50.80 99 204 8.3E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 249 5.7E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 Gene3D G3DSA:2.40.30.10 2 91 9.0E-11 T 23-10-2018 A3L12_02160 fe78bd7319ce25c7bf763a4fa1c19dc7 282 PIRSF PIRSF006816 1 256 1.5E-40 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 102 3.7E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 2.2E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 1.3E-85 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 Gene3D G3DSA:3.40.50.150 103 309 4.4E-69 T 23-10-2018 A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 2.8E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 2.8E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 2.8E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 2.8E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 2.8E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 SUPERFAMILY SSF53335 8 308 1.35E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_05885 aabcd4ebefe7986abffb26ffa8361287 309 Gene3D G3DSA:3.30.70.3130 1 101 1.9E-32 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 2.0E-10 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 2.0E-10 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 2.0E-10 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 2.0E-10 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 2.0E-10 T 23-10-2018 A3L12_05685 cf183ff93cca9ee9c3bfaf58c31a65b2 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 3.2E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 Pfam PF04055 Radical SAM superfamily 80 235 1.4E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 SMART SM00729 72 278 0.0048 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 Pfam PF13353 4Fe-4S single cluster domain 76 165 1.7E-7 T 23-10-2018 A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 PIRSF PIRSF004869 1 313 2.6E-100 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 SUPERFAMILY SSF102114 50 315 2.35E-38 T 23-10-2018 A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 345 4.2E-115 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A3L12_05980 4347a45f3c2634f6fe1823a812a20162 347 Gene3D G3DSA:3.20.20.70 63 286 1.8E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04255 fd38c0e6579fde2fe80b40c7ed759c7b 300 Gene3D G3DSA:3.30.230.10 27 158 1.3E-6 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_04255 fd38c0e6579fde2fe80b40c7ed759c7b 300 SUPERFAMILY SSF54211 1 158 5.31E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_04255 fd38c0e6579fde2fe80b40c7ed759c7b 300 PIRSF PIRSF016896 1 296 2.1E-89 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A3L12_04255 fd38c0e6579fde2fe80b40c7ed759c7b 300 Pfam PF00288 GHMP kinases N terminal domain 92 151 1.9E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L12_02450 9febd0e5e6e4099131bb9e21ce6a85cd 162 SUPERFAMILY SSF81333 6 70 2.62E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L12_02450 9febd0e5e6e4099131bb9e21ce6a85cd 162 SUPERFAMILY SSF81333 89 156 6.02E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L12_02450 9febd0e5e6e4099131bb9e21ce6a85cd 162 Gene3D G3DSA:1.20.120.610 2 158 2.2E-40 T 23-10-2018 A3L12_02450 9febd0e5e6e4099131bb9e21ce6a85cd 162 Pfam PF00137 ATP synthase subunit C 9 68 4.5E-12 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L12_02450 9febd0e5e6e4099131bb9e21ce6a85cd 162 Pfam PF00137 ATP synthase subunit C 97 155 1.6E-15 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L12_02670 18c3e7a65b177c9ea121571e646370d8 361 Gene3D G3DSA:3.20.20.70 24 286 3.0E-14 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_02670 18c3e7a65b177c9ea121571e646370d8 361 ProSitePatterns PS01087 Radical activating enzymes signature. 23 45 - T 23-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 A3L12_02670 18c3e7a65b177c9ea121571e646370d8 361 Pfam PF04055 Radical SAM superfamily 33 179 2.7E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_02670 18c3e7a65b177c9ea121571e646370d8 361 SUPERFAMILY SSF102114 27 206 3.53E-21 T 23-10-2018 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 92 - T 23-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 Pfam PF00459 Inositol monophosphatase family 6 250 6.9E-35 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 SUPERFAMILY SSF56655 6 247 4.71E-54 T 23-10-2018 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 Gene3D G3DSA:3.40.190.80 145 252 1.4E-28 T 23-10-2018 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 2.0E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 2.0E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 2.0E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 163 184 2.0E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 220 2.0E-28 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L12_06790 c06f923e2f06cdd06efc869bb1bcf8ae 252 Gene3D G3DSA:3.30.540.10 1 138 8.5E-36 T 23-10-2018 A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 PIRSF PIRSF018644 5 471 1.8E-186 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 SUPERFAMILY SSF159234 321 471 6.54E-30 T 23-10-2018 IPR035930 FomD-like superfamily A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 Gene3D G3DSA:2.40.380.10 340 471 1.7E-9 T 23-10-2018 IPR035930 FomD-like superfamily A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 34.034 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 Pfam PF10150 Ribonuclease E/G family 152 248 1.3E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A3L12_03750 3e85f0e0a2971a0b4383488c16808867 471 Pfam PF04167 Protein of unknown function (DUF402) 379 443 2.8E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L12_01255 534946b93f571411640c6d94f944f7d0 177 Gene3D G3DSA:3.30.300.130 72 176 2.4E-36 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_01255 534946b93f571411640c6d94f944f7d0 177 Pfam PF01883 Iron-sulfur cluster assembly protein 81 154 1.7E-21 T 23-10-2018 IPR002744 MIP18 family-like A3L12_01255 534946b93f571411640c6d94f944f7d0 177 SUPERFAMILY SSF117916 78 175 6.54E-33 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 3.0E-11 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 Gene3D G3DSA:2.40.50.140 70 135 1.2E-28 T 23-10-2018 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 2.3E-48 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 PIRSF PIRSF003025 1 136 1.6E-45 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 Gene3D G3DSA:2.30.30.30 2 69 1.1E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.631 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 SUPERFAMILY SSF50104 5 78 4.16E-21 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 5.1E-5 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 SUPERFAMILY SSF50249 71 133 2.83E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_05915 a325e817b77057870a7a094f3a0bfd70 136 SMART SM01376 70 134 6.1E-15 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 SMART SM00419 21 72 8.4E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 Pfam PF12802 MarR family 6 65 7.5E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 2.7E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 Gene3D G3DSA:3.30.70.920 83 154 4.0E-10 T 23-10-2018 A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 Gene3D G3DSA:1.10.10.10 6 82 2.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03465 d5ee46dec3914fd24e5fd91e6830c6cf 154 SUPERFAMILY SSF46785 31 138 1.9E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 Pfam PF00571 CBS domain 70 121 3.9E-12 T 23-10-2018 IPR000644 CBS domain A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 Pfam PF00571 CBS domain 134 184 2.2E-5 T 23-10-2018 IPR000644 CBS domain A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 Gene3D G3DSA:3.10.580.10 65 186 4.7E-27 T 23-10-2018 A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 SMART SM00116 77 124 6.0E-7 T 23-10-2018 IPR000644 CBS domain A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 SMART SM00116 141 187 0.37 T 23-10-2018 IPR000644 CBS domain A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 Pfam PF01381 Helix-turn-helix 13 60 8.7E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 SUPERFAMILY SSF54631 68 184 2.53E-26 T 23-10-2018 A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 SUPERFAMILY SSF47413 11 60 2.17E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 Gene3D G3DSA:1.10.260.40 10 63 8.3E-16 T 23-10-2018 A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 PIRSF PIRSF037253 2 187 5.6E-78 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A3L12_05460 93a4be1614b84f365d664db3d2489e90 187 SMART SM00530 12 68 2.2E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_00785 5615bc99469783f2e44914783de5899f 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 1.6E-61 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A3L12_00785 5615bc99469783f2e44914783de5899f 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A3L12_00785 5615bc99469783f2e44914783de5899f 142 SUPERFAMILY SSF52161 2 142 1.16E-42 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00785 5615bc99469783f2e44914783de5899f 142 Gene3D G3DSA:3.90.1180.10 1 142 9.1E-56 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00785 5615bc99469783f2e44914783de5899f 142 Pfam PF00572 Ribosomal protein L13 3 103 6.6E-12 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L12_00785 5615bc99469783f2e44914783de5899f 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.689 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L12_00785 5615bc99469783f2e44914783de5899f 142 PIRSF PIRSF002181 1 142 1.2E-42 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 SUPERFAMILY SSF52540 412 695 8.31E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Gene3D G3DSA:3.90.1570.50 104 279 3.5E-22 T 23-10-2018 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 12 701 2.9E-225 T 23-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Gene3D G3DSA:3.40.50.300 474 709 1.9E-41 T 23-10-2018 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 SMART SM00487 282 486 9.5E-20 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Pfam PF04851 Type III restriction enzyme, res subunit 297 455 3.9E-23 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 SUPERFAMILY SSF52540 247 511 1.1E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 212 6.7E-38 T 23-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Pfam PF11867 Domain of unknown function (DUF3387) 700 1004 3.0E-75 T 23-10-2018 IPR021810 Protein of unknown function DUF3387 A3L12_01335 e838567c0c7150cc5fefee772aeee377 1031 Gene3D G3DSA:3.40.50.300 285 473 7.3E-49 T 23-10-2018 A3L12_06850 a87b875eb8f09c83c3c5d2fceed4f844 237 Gene3D G3DSA:2.40.50.580 1 77 8.2E-25 T 23-10-2018 A3L12_06850 a87b875eb8f09c83c3c5d2fceed4f844 237 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 6 231 1.0E-53 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L12_06850 a87b875eb8f09c83c3c5d2fceed4f844 237 Gene3D G3DSA:3.40.1350.60 78 233 2.3E-41 T 23-10-2018 A3L12_06850 a87b875eb8f09c83c3c5d2fceed4f844 237 Pfam PF03749 Sugar fermentation stimulation protein 13 220 3.5E-48 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L12_06850 a87b875eb8f09c83c3c5d2fceed4f844 237 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 232 39.007 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L12_05590 bc60509e26245c2e126a9473448ff425 61 Pfam PF04021 Class III signal peptide 3 26 1.8E-5 T 23-10-2018 IPR007166 Class III signal peptide motif A3L12_01545 b6f0423c15e2eec8437321e9f53eace8 138 Gene3D G3DSA:2.60.120.630 1 138 1.4E-49 T 23-10-2018 IPR023131 Mth639-like domain superfamily A3L12_01545 b6f0423c15e2eec8437321e9f53eace8 138 Pfam PF04027 Domain of unknown function (DUF371) 6 137 1.4E-48 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A3L12_01555 18245782f73f789fda3b01e73461af96 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 62 5.9E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_01555 18245782f73f789fda3b01e73461af96 198 Gene3D G3DSA:1.10.10.10 4 105 6.5E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01555 18245782f73f789fda3b01e73461af96 198 SUPERFAMILY SSF46785 7 172 2.29E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01555 18245782f73f789fda3b01e73461af96 198 SMART SM00418 9 89 2.7E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 SUPERFAMILY SSF82861 77 160 5.23E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 Gene3D G3DSA:3.30.70.100 228 320 6.8E-29 T 23-10-2018 A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 Pfam PF00924 Mechanosensitive ion channel 117 316 8.4E-60 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 SUPERFAMILY SSF82689 229 326 2.48E-32 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 Gene3D G3DSA:2.30.30.60 177 226 2.6E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L12_03400 b07d8b324172212c0bbe7e0b09486158 336 SUPERFAMILY SSF50182 162 226 1.37E-18 T 23-10-2018 IPR010920 LSM domain superfamily A3L12_04765 21ac911d534b98f7bd02a6e1f1ed7832 232 Gene3D G3DSA:3.40.1350.10 107 218 1.2E-41 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L12_04765 21ac911d534b98f7bd02a6e1f1ed7832 232 Gene3D G3DSA:2.70.180.20 1 106 1.3E-37 T 23-10-2018 A3L12_04765 21ac911d534b98f7bd02a6e1f1ed7832 232 Pfam PF01939 Endonuclease NucS 9 220 4.1E-84 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L12_04765 21ac911d534b98f7bd02a6e1f1ed7832 232 Hamap MF_00722 Endonuclease NucS [nucS]. 10 223 38.002 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 SUPERFAMILY SSF55154 1 179 8.34E-36 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 Gene3D G3DSA:2.40.320.10 1 179 7.5E-56 T 23-10-2018 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 2.0E-57 T 23-10-2018 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 SMART SM01118 1 175 3.2E-26 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 173 2.6E-44 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L12_06185 6958a59b57fa1becdb10c9f64e3d7eb6 183 Pfam PF01928 CYTH domain 1 169 8.6E-35 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 Gene3D G3DSA:3.40.50.720 219 449 7.6E-66 T 23-10-2018 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 21 199 5.3E-41 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 SMART SM00984 335 431 2.2E-29 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 SUPERFAMILY SSF52413 322 442 2.88E-26 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 PIRSF PIRSF000124 20 446 2.6E-77 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 21 427 2.5E-129 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 Gene3D G3DSA:3.40.50.720 8 215 2.1E-59 T 23-10-2018 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 SUPERFAMILY SSF48179 220 314 1.09E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 308 4.1E-21 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 SUPERFAMILY SSF51735 21 213 5.1E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 PIRSF PIRSF500136 10 447 8.1E-143 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L12_02915 1f27471a6e12091ff503423f3fef1b25 450 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 335 431 7.1E-22 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L12_05395 27ed39ac48b604a4622aab200d9f2f0a 389 Pfam PF00155 Aminotransferase class I and II 28 378 5.0E-71 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_05395 27ed39ac48b604a4622aab200d9f2f0a 389 SUPERFAMILY SSF53383 2 385 4.71E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_05395 27ed39ac48b604a4622aab200d9f2f0a 389 Gene3D G3DSA:3.90.1150.10 29 378 2.0E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_05395 27ed39ac48b604a4622aab200d9f2f0a 389 Gene3D G3DSA:3.40.640.10 58 280 2.0E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_05395 27ed39ac48b604a4622aab200d9f2f0a 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 Pfam PF07998 Peptidase family M54 17 137 6.6E-20 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 Pfam PF07998 Peptidase family M54 159 221 5.0E-23 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 Gene3D G3DSA:3.40.390.10 77 220 6.1E-18 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 SUPERFAMILY SSF55486 170 217 1.62E-9 T 23-10-2018 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 PIRSF PIRSF005785 9 151 1.8E-10 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L12_08005 f197b0079e51bb705ba31f143a6b9243 228 PIRSF PIRSF005785 151 227 3.8E-25 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Pfam PF14520 Helix-hairpin-helix domain 601 650 8.8E-10 T 23-10-2018 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 SUPERFAMILY SSF47794 602 651 4.87E-8 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 SUPERFAMILY SSF88713 2 416 3.11E-121 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 SUPERFAMILY SSF88688 416 532 7.52E-29 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Gene3D G3DSA:1.20.1430.10 417 564 3.4E-54 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Gene3D G3DSA:1.10.150.20 590 654 5.0E-12 T 23-10-2018 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Pfam PF09210 Domain of unknown function (DUF1957) 428 526 2.1E-25 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Pfam PF03065 Glycosyl hydrolase family 57 6 391 2.2E-71 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L12_01015 dbbef50b5132c47ace5ad807e4aaea4f 654 Gene3D G3DSA:3.20.110.10 1 416 3.0E-179 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A3L12_00895 9193cbfca3e611827e928bccc2582384 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 2.8E-16 T 23-10-2018 A3L12_00895 9193cbfca3e611827e928bccc2582384 149 SUPERFAMILY SSF46785 1 61 1.02E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00895 9193cbfca3e611827e928bccc2582384 149 SMART SM00344 1 107 1.6E-41 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_00895 9193cbfca3e611827e928bccc2582384 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 9.5E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_00895 9193cbfca3e611827e928bccc2582384 149 Gene3D G3DSA:1.10.10.10 1 51 1.2E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_00895 9193cbfca3e611827e928bccc2582384 149 Gene3D G3DSA:3.30.70.920 53 146 5.2E-21 T 23-10-2018 A3L12_00895 9193cbfca3e611827e928bccc2582384 149 SUPERFAMILY SSF54909 61 144 8.58E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_00895 9193cbfca3e611827e928bccc2582384 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_00895 9193cbfca3e611827e928bccc2582384 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_00895 9193cbfca3e611827e928bccc2582384 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 Gene3D G3DSA:3.40.50.1000 3 216 5.8E-67 T 23-10-2018 IPR023214 HAD superfamily A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 219 1.0E-16 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 68 1.4E-8 T 23-10-2018 A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 SUPERFAMILY SSF56784 1 226 2.16E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 Gene3D G3DSA:3.30.980.20 94 176 5.8E-67 T 23-10-2018 A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 3 228 5.7E-66 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L12_01815 f9cdc9d36ebb1a11b2750eac3883f90a 243 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 3 222 9.4E-77 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L12_01330 7ab5b7add239cbfda1c988ea5334bb49 152 Gene3D G3DSA:3.40.50.360 1 149 1.7E-29 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L12_01330 7ab5b7add239cbfda1c988ea5334bb49 152 Pfam PF12682 Flavodoxin 2 139 1.4E-4 T 23-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A3L12_01330 7ab5b7add239cbfda1c988ea5334bb49 152 SUPERFAMILY SSF52218 2 127 1.44E-18 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 PIRSF PIRSF001123 1 344 1.1E-99 T 23-10-2018 IPR008007 Peptidase M42 A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 Gene3D G3DSA:2.40.30.40 68 160 4.0E-129 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 330 7.7E-95 T 23-10-2018 IPR008007 Peptidase M42 A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 Gene3D G3DSA:3.40.630.10 7 331 4.0E-129 T 23-10-2018 A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 SUPERFAMILY SSF53187 4 340 2.79E-62 T 23-10-2018 A3L12_06180 7b59e5a80dc68b12f65c4465e0ae6332 345 SUPERFAMILY SSF101821 68 176 4.43E-27 T 23-10-2018 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 SUPERFAMILY SSF55666 154 241 7.33E-25 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 2.5E-35 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 1.0E-117 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 Gene3D G3DSA:3.30.230.70 5 245 1.1E-76 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 60.331 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 2.6E-16 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00460 433a33cb76e8c17da5c84825dd40a53d 249 SUPERFAMILY SSF54211 10 180 1.06E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_00875 484b5725bdd95e701c8effcf164ce52c 79 Gene3D G3DSA:3.30.70.920 1 74 4.6E-19 T 23-10-2018 A3L12_00875 484b5725bdd95e701c8effcf164ce52c 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.4E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_00875 484b5725bdd95e701c8effcf164ce52c 79 SUPERFAMILY SSF54909 2 74 6.17E-14 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 Gene3D G3DSA:3.30.70.330 1 98 4.3E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 SUPERFAMILY SSF54189 1 97 3.06E-32 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 Pfam PF01282 Ribosomal protein S24e 21 97 4.3E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.321 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03255 c049599e5f0b6ab37c56603cbe760bac 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 2.0E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.2E-18 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 SUPERFAMILY SSF50249 80 179 3.58E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 Pfam PF00575 S1 RNA binding domain 78 154 2.1E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 SMART SM00316 80 166 4.2E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 Gene3D G3DSA:3.30.1490.120 1 81 4.7E-31 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 2.7E-68 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 SUPERFAMILY SSF88798 1 78 2.22E-20 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L12_03270 a3a7807b667ef830d2d90f8fd472ac03 186 Gene3D G3DSA:2.40.50.140 82 186 3.7E-33 T 23-10-2018 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 Pfam PF01472 PUA domain 89 161 6.1E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 SMART SM00359 88 163 1.7E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 SUPERFAMILY SSF88697 88 169 7.73E-24 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 76 1.7E-6 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 52 164 1.1E-29 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 1.6E-55 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 Gene3D G3DSA:3.10.450.120 1 78 3.0E-30 T 23-10-2018 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 PIRSF PIRSF005067 1 172 2.7E-43 T 23-10-2018 IPR016437 MCT-1/Tma20 A3L12_02100 dbe5207d3111f703ff2ea360a010c0dc 172 Gene3D G3DSA:2.30.130.10 79 171 3.2E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_07235 e3928b45c1c61357c777f4a627868c09 140 PIRSF PIRSF016702 1 139 2.7E-42 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A3L12_07235 e3928b45c1c61357c777f4a627868c09 140 SUPERFAMILY SSF117856 4 129 2.62E-36 T 23-10-2018 A3L12_07235 e3928b45c1c61357c777f4a627868c09 140 Gene3D G3DSA:3.30.1330.80 1 140 1.4E-46 T 23-10-2018 A3L12_07235 e3928b45c1c61357c777f4a627868c09 140 Pfam PF03479 Domain of unknown function (DUF296) 8 117 1.0E-19 T 23-10-2018 IPR005175 PPC domain A3L12_00660 a70feb67ffabcf96073624a302242421 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 1.6E-25 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00660 a70feb67ffabcf96073624a302242421 183 Pfam PF00281 Ribosomal protein L5 16 68 9.1E-19 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00660 a70feb67ffabcf96073624a302242421 183 Gene3D G3DSA:3.30.1440.10 10 182 1.5E-70 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00660 a70feb67ffabcf96073624a302242421 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.543 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00660 a70feb67ffabcf96073624a302242421 183 PIRSF PIRSF002161 2 180 6.7E-54 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00660 a70feb67ffabcf96073624a302242421 183 SUPERFAMILY SSF55282 15 180 6.36E-55 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 186 197 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 Gene3D G3DSA:3.40.50.200 163 283 1.2E-6 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 SUPERFAMILY SSF52743 84 726 1.67E-61 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 574 584 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 Pfam PF00082 Subtilase family 181 626 6.2E-59 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 380 390 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 Gene3D G3DSA:3.40.50.200 315 643 6.3E-69 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 PRINTS PR00723 Subtilisin serine protease family (S8) signature 181 200 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 PRINTS PR00723 Subtilisin serine protease family (S8) signature 376 389 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_01125 6b5b02f10979d5046727e41f03beb6a0 1423 PRINTS PR00723 Subtilisin serine protease family (S8) signature 573 589 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 Pfam PF00106 short chain dehydrogenase 6 194 1.8E-56 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 0.009 T 23-10-2018 A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 SUPERFAMILY SSF51735 4 239 1.46E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L12_05775 f144add8acc4f37cf38415b41c9216c3 240 Gene3D G3DSA:3.40.50.720 2 239 1.2E-77 T 23-10-2018 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 SUPERFAMILY SSF50249 225 294 7.54E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Gene3D G3DSA:2.10.230.10 1 87 2.3E-7 T 23-10-2018 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 SUPERFAMILY SSF57938 5 32 5.89E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 SUPERFAMILY SSF50249 125 193 1.25E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Gene3D G3DSA:3.90.1640.30 333 542 1.2E-7 T 23-10-2018 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 291 1.8E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Gene3D G3DSA:2.40.50.140 128 202 6.2E-13 T 23-10-2018 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Pfam PF00575 S1 RNA binding domain 131 193 1.9E-10 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 SMART SM00316 131 196 3.2E-13 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 SUPERFAMILY SSF64182 337 734 7.33E-40 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L12_00375 97f2482d543b46456b6f81e2221c03d9 741 Gene3D G3DSA:2.40.50.140 213 299 1.2E-6 T 23-10-2018 A3L12_03300 b255e2528af1557c42e6fc0bb8fed668 177 Pfam PF06510 Protein of unknown function (DUF1102) 38 174 2.1E-43 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L12_01495 b54f2fc855d7dce339e1df40dbbeb8bb 277 SUPERFAMILY SSF161098 9 269 1.44E-52 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01495 b54f2fc855d7dce339e1df40dbbeb8bb 277 Gene3D G3DSA:1.10.3720.10 3 270 4.9E-50 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01495 b54f2fc855d7dce339e1df40dbbeb8bb 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 1.9E-20 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 SMART SM00418 44 118 5.9E-28 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 Gene3D G3DSA:1.10.10.10 28 123 1.8E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 4.0E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 2.4E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 2.4E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.4E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.4E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05510 e340a1ee6c56539c6b95d5918da47fad 125 SUPERFAMILY SSF46785 42 119 2.18E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_02595 275db09b3c300c3c349232d726903b66 396 SUPERFAMILY SSF88697 1 70 8.95E-18 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_02595 275db09b3c300c3c349232d726903b66 396 Gene3D G3DSA:3.40.50.150 179 396 1.0E-70 T 23-10-2018 A3L12_02595 275db09b3c300c3c349232d726903b66 396 SMART SM00359 2 87 7.9E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_02595 275db09b3c300c3c349232d726903b66 396 SUPERFAMILY SSF53335 78 389 2.45E-67 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_02595 275db09b3c300c3c349232d726903b66 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 331 1.1E-18 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A3L12_02595 275db09b3c300c3c349232d726903b66 396 Gene3D G3DSA:3.30.750.80 72 178 5.7E-37 T 23-10-2018 A3L12_02595 275db09b3c300c3c349232d726903b66 396 Gene3D G3DSA:2.30.130.10 1 71 1.8E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_02595 275db09b3c300c3c349232d726903b66 396 Pfam PF01472 PUA domain 3 64 3.7E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_06505 6a80153b2069bd8cfe8dc8926c9b5816 312 Pfam PF00005 ABC transporter 23 165 4.7E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06505 6a80153b2069bd8cfe8dc8926c9b5816 312 Gene3D G3DSA:3.40.50.300 2 236 2.0E-59 T 23-10-2018 A3L12_06505 6a80153b2069bd8cfe8dc8926c9b5816 312 SUPERFAMILY SSF52540 4 225 1.6E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06505 6a80153b2069bd8cfe8dc8926c9b5816 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_06505 6a80153b2069bd8cfe8dc8926c9b5816 312 SMART SM00382 30 230 1.4E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 SUPERFAMILY SSF51246 339 410 9.26E-18 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 49.386 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 SUPERFAMILY SSF52440 8 115 5.32E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 Gene3D G3DSA:3.30.1490.20 129 200 3.6E-31 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 SUPERFAMILY SSF56059 118 324 9.26E-53 T 23-10-2018 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 Pfam PF02222 ATP-grasp domain 127 303 2.2E-56 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 Gene3D G3DSA:3.30.470.20 201 430 6.4E-79 T 23-10-2018 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 7.7E-189 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L12_03130 75efde252946256ede723b7d1b8c44e7 430 Gene3D G3DSA:3.40.50.20 1 128 4.0E-56 T 23-10-2018 A3L12_04640 baa5ed1f196db2610173a31d0e8faee2 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.665 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L12_04640 baa5ed1f196db2610173a31d0e8faee2 255 SUPERFAMILY SSF88713 1 252 1.11E-103 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_04640 baa5ed1f196db2610173a31d0e8faee2 255 Gene3D G3DSA:3.20.20.370 1 255 4.4E-111 T 23-10-2018 A3L12_04640 baa5ed1f196db2610173a31d0e8faee2 255 Pfam PF03746 LamB/YcsF family 3 241 4.4E-105 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 Gene3D G3DSA:3.90.1150.10 5 420 3.2E-143 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 Gene3D G3DSA:3.40.640.10 59 324 3.2E-143 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 SUPERFAMILY SSF53383 22 426 8.76E-125 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 Pfam PF00202 Aminotransferase class-III 23 424 1.1E-110 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 PIRSF PIRSF000521 28 130 1.2E-4 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 PIRSF PIRSF000521 122 427 2.6E-32 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04935 3ad6a91c5f8505e2272d516063690315 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_01825 c16d60424fc5b94526b55b0919d260c3 453 Gene3D G3DSA:3.40.1190.20 24 447 3.1E-150 T 23-10-2018 IPR029056 Ribokinase-like A3L12_01825 c16d60424fc5b94526b55b0919d260c3 453 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 23 447 1.0E-93 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L12_01825 c16d60424fc5b94526b55b0919d260c3 453 SUPERFAMILY SSF53613 2 451 3.33E-150 T 23-10-2018 IPR029056 Ribokinase-like A3L12_01825 c16d60424fc5b94526b55b0919d260c3 453 Gene3D G3DSA:3.30.1110.20 31 203 3.1E-150 T 23-10-2018 A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 Gene3D G3DSA:3.40.50.920 253 391 1.8E-39 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 SUPERFAMILY SSF52518 4 251 1.65E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 Gene3D G3DSA:3.40.50.970 2 252 4.7E-104 T 23-10-2018 A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 364 2.5E-28 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 1.1E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_04040 f6afa7b8e31b5734d72d038f1a47bd1b 394 SUPERFAMILY SSF52922 254 370 1.96E-31 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 Pfam PF01381 Helix-turn-helix 15 62 1.6E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 SUPERFAMILY SSF47413 13 62 5.96E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 SMART SM00530 13 68 1.5E-4 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 SUPERFAMILY SSF53271 76 237 1.84E-32 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 Pfam PF00156 Phosphoribosyl transferase domain 99 214 1.9E-11 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_00885 6c4a1a7889cff919d2d07c40e01226af 238 Gene3D G3DSA:3.40.50.2020 63 238 8.3E-38 T 23-10-2018 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Gene3D G3DSA:1.10.472.170 5 201 7.9E-65 T 23-10-2018 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 SUPERFAMILY SSF57783 4 49 9.07E-15 T 23-10-2018 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Pfam PF00382 Transcription factor TFIIB repeat 122 191 2.9E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Pfam PF00382 Transcription factor TFIIB repeat 215 285 7.0E-18 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 SUPERFAMILY SSF47954 210 301 6.05E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 SMART SM00385 213 294 2.2E-10 T 23-10-2018 IPR013763 Cyclin-like A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 SMART SM00385 119 200 9.1E-11 T 23-10-2018 IPR013763 Cyclin-like A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 53 74 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 161 180 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 214 232 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 40 53 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 280 294 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 18 38 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 248 264 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 PRINTS PR00685 Transcription initiation factor IIB signature 187 202 2.0E-54 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Gene3D G3DSA:1.10.472.10 210 302 1.3E-25 T 23-10-2018 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 247 262 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 300 44.429 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 Pfam PF08271 TFIIB zinc-binding 5 46 5.7E-16 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 SUPERFAMILY SSF47954 113 206 4.02E-24 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L12_02055 e506e2ee82a568a02aacb9b25d751a1b 302 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 153 168 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L12_07415 ce19bfd2d3a6e48d58f50c63556d6d26 176 Pfam PF06197 Protein of unknown function (DUF998) 9 174 1.3E-24 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L12_02230 2c8c44226e94c7cfc75721b4183a3635 178 SMART SM00530 91 146 7.6E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_02230 2c8c44226e94c7cfc75721b4183a3635 178 Pfam PF01381 Helix-turn-helix 96 145 3.5E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_02230 2c8c44226e94c7cfc75721b4183a3635 178 Gene3D G3DSA:1.10.260.40 80 178 4.1E-11 T 23-10-2018 A3L12_02230 2c8c44226e94c7cfc75721b4183a3635 178 SUPERFAMILY SSF47413 81 145 5.91E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_02230 2c8c44226e94c7cfc75721b4183a3635 178 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 172 7.2E-19 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A3L12_03245 f1fd5d61b59b4427ccfb8739d3746760 192 SUPERFAMILY SSF53335 3 180 1.32E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03245 f1fd5d61b59b4427ccfb8739d3746760 192 Pfam PF05175 Methyltransferase small domain 22 163 2.8E-16 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L12_03245 f1fd5d61b59b4427ccfb8739d3746760 192 Gene3D G3DSA:3.40.50.150 4 181 7.1E-37 T 23-10-2018 A3L12_03245 f1fd5d61b59b4427ccfb8739d3746760 192 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 188 6.0E-57 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A3L12_07185 a23875fb3c486dd5ea568b09ae0e8fe3 199 Gene3D G3DSA:1.10.10.10 10 92 1.6E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07185 a23875fb3c486dd5ea568b09ae0e8fe3 199 SMART SM00418 15 94 0.0026 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_07185 a23875fb3c486dd5ea568b09ae0e8fe3 199 Pfam PF12840 Helix-turn-helix domain 15 70 9.1E-12 T 23-10-2018 A3L12_07185 a23875fb3c486dd5ea568b09ae0e8fe3 199 SUPERFAMILY SSF46785 7 95 7.61E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 SUPERFAMILY SSF53706 4 566 6.67E-217 T 23-10-2018 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Pfam PF00384 Molybdopterin oxidoreductase 58 477 3.9E-103 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Pfam PF01568 Molydopterin dinucleotide binding domain 564 665 2.2E-30 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Gene3D G3DSA:2.20.25.90 5 54 1.7E-11 T 23-10-2018 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 8 670 2.3E-270 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Gene3D G3DSA:3.40.50.740 63 521 1.8E-194 T 23-10-2018 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 53 1.3E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 SUPERFAMILY SSF50692 526 672 4.07E-48 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Gene3D G3DSA:2.40.40.20 554 673 2.4E-42 T 23-10-2018 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 SMART SM00926 2 55 3.2E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_01285 94c4baa92f895e166ef320a8259caf1b 674 Gene3D G3DSA:3.40.228.10 135 333 1.8E-194 T 23-10-2018 A3L12_06610 ee67413b3ef00bef5e3063c2452412dc 233 Gene3D G3DSA:3.30.460.10 21 93 1.7E-7 T 23-10-2018 A3L12_06610 ee67413b3ef00bef5e3063c2452412dc 233 SUPERFAMILY SSF81301 21 74 3.45E-9 T 23-10-2018 A3L12_06610 ee67413b3ef00bef5e3063c2452412dc 233 PIRSF PIRSF005928 10 232 1.6E-98 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A3L12_06610 ee67413b3ef00bef5e3063c2452412dc 233 Pfam PF01909 Nucleotidyltransferase domain 31 72 7.4E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Gene3D G3DSA:3.40.120.10 257 364 4.8E-74 T 23-10-2018 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Gene3D G3DSA:3.40.120.10 169 357 4.8E-74 T 23-10-2018 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Gene3D G3DSA:3.40.120.10 1 152 2.0E-60 T 23-10-2018 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 440 6.6E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 SUPERFAMILY SSF53738 2 145 5.1E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 SUPERFAMILY SSF53738 244 372 9.03E-25 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 368 4.1E-26 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 SUPERFAMILY SSF53738 155 259 6.67E-30 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 SUPERFAMILY SSF55957 358 454 1.7E-21 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 4.7E-47 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Gene3D G3DSA:3.30.310.50 370 454 1.4E-29 T 23-10-2018 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.3E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 1.3E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.3E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.3E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 446 1.2E-174 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01800 be825108caebb45130ad1c0fb072c898 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 1.3E-29 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 1.3E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 581 710 3.6E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:1.10.8.60 434 533 8.9E-15 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:1.10.8.60 379 417 1.3E-5 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 2.5E-31 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SMART SM01072 116 200 1.1E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:2.40.40.20 8 98 2.9E-34 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 ProSitePatterns PS00674 AAA-protein family signature. 681 699 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:3.40.50.300 203 378 3.6E-75 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:3.40.50.300 535 710 3.9E-75 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SUPERFAMILY SSF54585 98 213 1.11E-16 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Gene3D G3DSA:1.10.8.60 712 820 3.8E-31 T 23-10-2018 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SUPERFAMILY SSF50692 10 96 1.1E-28 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 820 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SMART SM00382 577 713 1.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SMART SM00382 244 380 1.0E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 121 200 2.2E-13 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SMART SM01073 14 98 3.8E-38 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SUPERFAMILY SSF52540 539 816 7.99E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06590 5d8d237757d1112be47408d889ff0bed 834 SUPERFAMILY SSF52540 206 529 5.9E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SUPERFAMILY SSF50692 2 91 2.98E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 2.2E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SUPERFAMILY SSF52540 511 790 9.4E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 792 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:1.10.8.60 684 792 1.9E-33 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:2.40.40.20 1 92 2.0E-37 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SMART SM01072 107 170 1.9E-17 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SMART SM00382 215 351 1.7E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SMART SM00382 549 685 4.0E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SUPERFAMILY SSF54585 92 184 3.92E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:3.40.50.300 179 349 1.1E-82 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 1.6E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:3.10.330.10 93 173 4.6E-7 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:1.10.8.60 426 505 9.1E-18 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SMART SM01073 8 92 2.1E-43 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:1.10.8.60 350 406 1.1E-82 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.7E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 553 682 3.2E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 ProSitePatterns PS00674 AAA-protein family signature. 653 671 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 Gene3D G3DSA:3.40.50.300 507 682 3.2E-74 T 23-10-2018 A3L12_06490 01dd94d312519e5c1623c6633a88b720 796 SUPERFAMILY SSF52540 179 502 1.04E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07285 6fef580b10d8bdce45f0a41990909861 317 SMART SM00729 15 228 2.1E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_07285 6fef580b10d8bdce45f0a41990909861 317 Pfam PF04055 Radical SAM superfamily 25 188 2.1E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_07285 6fef580b10d8bdce45f0a41990909861 317 SUPERFAMILY SSF102114 25 228 8.63E-21 T 23-10-2018 A3L12_07285 6fef580b10d8bdce45f0a41990909861 317 Gene3D G3DSA:3.20.20.70 18 259 3.6E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 Gene3D G3DSA:2.40.50.1000 1 111 3.0E-38 T 23-10-2018 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 SUPERFAMILY SSF50249 29 109 5.83E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 Pfam PF00366 Ribosomal protein S17 35 102 5.3E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.909 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 7.0E-32 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00640 ca9cdbc0d7b7578faabc5ddb6bd2b693 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 2.9E-48 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05125 a3897dc49b3ad4967b77f83f62c3b1f4 275 Pfam PF01008 Initiation factor 2 subunit family 18 271 1.1E-50 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L12_05125 a3897dc49b3ad4967b77f83f62c3b1f4 275 SUPERFAMILY SSF100950 4 272 4.5E-66 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L12_05125 a3897dc49b3ad4967b77f83f62c3b1f4 275 Gene3D G3DSA:3.40.50.10470 96 275 4.1E-61 T 23-10-2018 A3L12_05125 a3897dc49b3ad4967b77f83f62c3b1f4 275 Gene3D G3DSA:1.20.120.420 1 95 2.0E-33 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 Gene3D G3DSA:1.10.510.10 95 215 8.3E-33 T 23-10-2018 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 Pfam PF01163 RIO1 family 40 147 3.3E-15 T 23-10-2018 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 SMART SM00220 1 220 0.0021 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 3 214 4.0E-73 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 124 136 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 SUPERFAMILY SSF56112 2 154 6.56E-28 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L12_07715 2818fcb8dd703adaf0b636aca9bb074f 221 Gene3D G3DSA:3.30.200.20 9 88 8.4E-25 T 23-10-2018 A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 Pfam PF09202 Rio2, N-terminal 13 92 3.5E-22 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 Pfam PF01163 RIO1 family 111 289 2.1E-44 T 23-10-2018 A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 Gene3D G3DSA:1.10.510.10 204 297 5.3E-15 T 23-10-2018 A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 Gene3D G3DSA:3.30.200.20 96 196 8.2E-23 T 23-10-2018 A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 SUPERFAMILY SSF56112 103 273 6.42E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 SUPERFAMILY SSF46785 8 94 3.96E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 Gene3D G3DSA:1.10.10.10 5 94 3.6E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03670 ff5e756bfed3ebe49e9c04d414d97cbc 312 SMART SM00090 68 299 7.4E-75 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 5.8E-20 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 5.8E-20 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 5.8E-20 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 Gene3D G3DSA:3.30.860.20 2 133 3.0E-54 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 Pfam PF00203 Ribosomal protein S19 35 116 1.5E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 PIRSF PIRSF002144 1 133 9.4E-40 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.658 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 SUPERFAMILY SSF54570 34 117 4.45E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 5.6E-66 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00610 0aa137aec593e72100740f3196dda0c9 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 1.4E-27 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 Gene3D G3DSA:3.40.50.300 212 384 2.8E-51 T 23-10-2018 A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 SUPERFAMILY SSF52540 71 352 1.48E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 Pfam PF00271 Helicase conserved C-terminal domain 241 333 7.1E-26 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 SMART SM00490 252 333 5.0E-32 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 Pfam PF00270 DEAD/DEAH box helicase 25 192 1.4E-46 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 Gene3D G3DSA:3.40.50.300 1 207 8.1E-75 T 23-10-2018 A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 SMART SM00487 20 218 2.2E-63 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06815 d05a3dbc11ad23fc15aa5c838821ef6d 388 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Gene3D G3DSA:1.10.730.10 669 852 3.7E-55 T 23-10-2018 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 5 1065 13.766 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Gene3D G3DSA:3.40.50.620 16 651 3.0E-231 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 3.6E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 3.6E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 3.6E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 3.6E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 3.6E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 SUPERFAMILY SSF47323 983 1048 1.16E-5 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Pfam PF08264 Anticodon-binding domain of tRNA 710 859 2.2E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 1.2E-189 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 SUPERFAMILY SSF52374 9 674 5.18E-130 T 23-10-2018 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 SUPERFAMILY SSF47323 677 910 4.67E-60 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 874 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 Gene3D G3DSA:3.90.740.10 199 405 3.0E-231 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_02675 197d2bf63498cc266d6f928a9c5a7e04 1066 SUPERFAMILY SSF50677 203 401 2.09E-54 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 Gene3D G3DSA:3.30.56.70 318 375 5.6E-19 T 23-10-2018 A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 376 41.641 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 SUPERFAMILY SSF53335 6 374 4.41E-102 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 11 374 1.0E-105 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 Gene3D G3DSA:3.40.50.150 2 317 1.2E-94 T 23-10-2018 A3L12_05065 2a2977405707545449bc5e1491bf0b59 376 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 374 4.5E-90 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 3.9E-31 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 SUPERFAMILY SSF55315 4 120 1.47E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 34.756 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 3.5E-56 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 Gene3D G3DSA:3.30.1330.30 1 123 3.3E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 3.8E-29 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 3.8E-29 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 3.8E-29 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 3.8E-29 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07070 9c0a2cf553c3bdadde02dcb61f06136a 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 3.8E-29 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_03435 c050d178cbb1b4e96ee4ecc2291f5536 137 SUPERFAMILY SSF88723 6 129 2.19E-25 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_03435 c050d178cbb1b4e96ee4ecc2291f5536 137 Pfam PF04900 Fcf1 32 129 3.5E-7 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A3L12_03435 c050d178cbb1b4e96ee4ecc2291f5536 137 Gene3D G3DSA:3.40.50.1010 6 135 4.0E-29 T 23-10-2018 A3L12_03435 c050d178cbb1b4e96ee4ecc2291f5536 137 SMART SM00670 6 112 1.5E-8 T 23-10-2018 IPR002716 PIN domain A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 SUPERFAMILY SSF52540 327 571 4.7E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 Pfam PF00005 ABC transporter 354 502 4.6E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 Gene3D G3DSA:1.20.1560.10 3 326 2.6E-80 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 Gene3D G3DSA:3.40.50.300 328 577 1.9E-93 T 23-10-2018 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 SUPERFAMILY SSF90123 10 326 2.22E-72 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 Pfam PF00664 ABC transporter transmembrane region 24 293 5.1E-44 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L12_03590 34b8edb6db0c35fae430a47e641f499b 578 SMART SM00382 363 549 6.5E-20 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 Gene3D G3DSA:3.90.1170.20 1 106 3.0E-46 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 PIRSF PIRSF000484 9 71 8.6 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 PIRSF PIRSF000484 69 387 4.0E-47 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 SUPERFAMILY SSF51690 112 386 6.93E-74 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 SUPERFAMILY SSF54675 2 115 2.75E-32 T 23-10-2018 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 Gene3D G3DSA:3.20.140.10 300 388 2.2E-5 T 23-10-2018 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 53 113 2.4E-5 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 2.8E-24 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L12_01245 e2e5ff7ba3aafe1b57a59dc62c93a9c4 390 Gene3D G3DSA:3.20.20.70 107 297 2.1E-61 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 SUPERFAMILY SSF52166 1 252 1.3E-70 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 Gene3D G3DSA:3.40.1370.10 1 255 1.8E-97 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 4.1E-114 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.017 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00595 56637e24e48f3c9ab26b7a21e7f769c0 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 8.4E-48 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A3L12_03105 271284357e2f41c4396275db9dca86b9 197 PIRSF PIRSF005639 1 197 6.5E-68 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03105 271284357e2f41c4396275db9dca86b9 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 194 2.8E-74 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03105 271284357e2f41c4396275db9dca86b9 197 SUPERFAMILY SSF52317 2 195 2.07E-47 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_03105 271284357e2f41c4396275db9dca86b9 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03105 271284357e2f41c4396275db9dca86b9 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 2.5E-56 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_03105 271284357e2f41c4396275db9dca86b9 197 Gene3D G3DSA:3.40.50.880 1 197 3.3E-68 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_03105 271284357e2f41c4396275db9dca86b9 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.494 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 SUPERFAMILY SSF53137 2 191 2.78E-60 T 23-10-2018 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 7.3E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 93 2.1E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 Gene3D G3DSA:3.30.420.100 1 194 2.3E-70 T 23-10-2018 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 189 44.346 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 Pfam PF14204 Ribosomal L18 C-terminal region 143 191 1.3E-8 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 PRINTS PR00058 Ribosomal protein L5 signature 1 12 4.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 PRINTS PR00058 Ribosomal protein L5 signature 103 122 4.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00690 b5f88810bb6ff776f72fa664a1e35eab 198 PRINTS PR00058 Ribosomal protein L5 signature 123 142 4.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07380 faddb5c81e87f154b0ff700b1346fbea 187 Pfam PF00583 Acetyltransferase (GNAT) family 34 159 6.5E-12 T 23-10-2018 IPR000182 GNAT domain A3L12_07380 faddb5c81e87f154b0ff700b1346fbea 187 Gene3D G3DSA:3.40.630.30 2 143 1.1E-58 T 23-10-2018 A3L12_07380 faddb5c81e87f154b0ff700b1346fbea 187 SUPERFAMILY SSF55729 14 164 1.71E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_07380 faddb5c81e87f154b0ff700b1346fbea 187 Gene3D G3DSA:3.30.1990.20 144 178 4.3E-7 T 23-10-2018 A3L12_00395 c2cc85a5ae337a9b44454a178324e8cf 128 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 119 2.9E-10 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A3L12_00395 c2cc85a5ae337a9b44454a178324e8cf 128 Gene3D G3DSA:3.10.129.10 1 128 1.4E-41 T 23-10-2018 A3L12_00395 c2cc85a5ae337a9b44454a178324e8cf 128 Pfam PF03061 Thioesterase superfamily 40 111 1.0E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A3L12_00395 c2cc85a5ae337a9b44454a178324e8cf 128 SUPERFAMILY SSF54637 14 119 3.87E-26 T 23-10-2018 IPR029069 HotDog domain superfamily A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 SUPERFAMILY SSF51366 2 208 1.51E-58 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 36.531 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 SMART SM00934 3 203 1.4E-61 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 203 8.2E-48 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 202 1.6E-34 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 Gene3D G3DSA:3.20.20.70 3 208 4.9E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_02095 e4a79e36b7e14cb2cf3ba83bfe99b5c0 212 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 Gene3D G3DSA:3.30.200.20 21 230 1.7E-94 T 23-10-2018 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 SUPERFAMILY SSF56104 6 232 1.96E-78 T 23-10-2018 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 32.615 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 Gene3D G3DSA:3.30.470.20 84 219 1.7E-94 T 23-10-2018 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 Pfam PF01259 SAICAR synthetase 7 226 1.9E-65 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 210 2.3E-73 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_03115 0f4b96979f7d337ee99b880dd08a8f8d 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_03520 44ffc40c87d42922a7b7238d30313eaf 273 Pfam PF00753 Metallo-beta-lactamase superfamily 22 98 2.0E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_03520 44ffc40c87d42922a7b7238d30313eaf 273 Gene3D G3DSA:3.60.15.10 1 270 9.9E-87 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_03520 44ffc40c87d42922a7b7238d30313eaf 273 SMART SM00849 21 242 6.7E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_03520 44ffc40c87d42922a7b7238d30313eaf 273 SUPERFAMILY SSF56281 4 271 9.57E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 SUPERFAMILY SSF51338 1 423 1.4E-35 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 Pfam PF01979 Amidohydrolase family 52 397 2.1E-74 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 SUPERFAMILY SSF51556 54 347 2.16E-105 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 Gene3D G3DSA:2.30.40.10 4 415 3.3E-155 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 47.84 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A3L12_08110 c15f53cd9608410f4d362ab64cbd14fa 425 Gene3D G3DSA:3.20.20.140 55 344 3.3E-155 T 23-10-2018 A3L12_06390 e56ba95ee305e354d6cc772d651ebc16 204 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 193 2.7E-55 T 23-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type A3L12_06390 e56ba95ee305e354d6cc772d651ebc16 204 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 43 1.9E-16 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal A3L12_06390 e56ba95ee305e354d6cc772d651ebc16 204 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 2 43 3.5E-5 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 A3L12_02620 010f35743bebf1d3e7c5aaa869e3d7b7 134 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 5.0E-33 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L12_02620 010f35743bebf1d3e7c5aaa869e3d7b7 134 SUPERFAMILY SSF53335 4 88 1.15E-5 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_02620 010f35743bebf1d3e7c5aaa869e3d7b7 134 Hamap MF_00341 UPF0146 protein . 3 132 24.343 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L12_02620 010f35743bebf1d3e7c5aaa869e3d7b7 134 Pfam PF03686 Uncharacterised protein family (UPF0146) 5 130 1.4E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L12_02620 010f35743bebf1d3e7c5aaa869e3d7b7 134 Gene3D G3DSA:3.40.50.150 2 133 1.3E-22 T 23-10-2018 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 SUPERFAMILY SSF50447 1 83 6.71E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 Pfam PF01411 tRNA synthetases class II (A) 13 86 2.4E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 SMART SM00863 164 207 3.3E-7 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 Gene3D G3DSA:2.40.30.130 13 83 1.0E-28 T 23-10-2018 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 SUPERFAMILY SSF55186 84 209 7.46E-33 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 Gene3D G3DSA:3.30.980.10 84 211 1.2E-40 T 23-10-2018 A3L12_07340 cd414171e0c1288415232e2e20daadfd 212 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 207 5.7E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 Gene3D G3DSA:3.20.20.100 8 270 1.3E-84 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PIRSF PIRSF000097 119 270 2.1E-17 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PIRSF PIRSF000097 2 125 6.8E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 Pfam PF00248 Aldo/keto reductase family 15 271 3.6E-58 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.3E-16 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PRINTS PR00069 Aldo-keto reductase signature 131 148 1.3E-16 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.3E-16 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 PRINTS PR00069 Aldo-keto reductase signature 206 230 1.3E-16 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L12_05855 0f7bfb8e7d8947c332b28c92dc5eb1ce 272 SUPERFAMILY SSF51430 10 267 2.23E-74 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SUPERFAMILY SSF158702 493 700 1.86E-58 T 23-10-2018 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SMART SM00487 20 204 2.1E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Gene3D G3DSA:1.10.3380.30 411 640 8.1E-73 T 23-10-2018 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Gene3D G3DSA:1.10.150.20 642 698 2.4E-20 T 23-10-2018 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 699 30.64 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SUPERFAMILY SSF46785 405 492 3.81E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SMART SM00278 677 696 12.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SMART SM00278 644 663 0.073 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Pfam PF00270 DEAD/DEAH box helicase 26 180 7.6E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SUPERFAMILY SSF52540 36 386 4.52E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Gene3D G3DSA:3.40.50.300 8 200 2.7E-72 T 23-10-2018 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 SMART SM00490 288 374 7.6E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Pfam PF00271 Helicase conserved C-terminal domain 233 374 2.8E-10 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Pfam PF14520 Helix-hairpin-helix domain 645 686 1.8E-9 T 23-10-2018 A3L12_01165 6e34c61b626eefe97dff8c7ea41c96c0 718 Gene3D G3DSA:3.40.50.300 201 399 8.8E-63 T 23-10-2018 A3L12_06420 be78c074f620f9b6c4fb17806976115c 254 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 33 194 2.1E-13 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type A3L12_06420 be78c074f620f9b6c4fb17806976115c 254 Gene3D G3DSA:3.30.70.3120 26 251 7.7E-20 T 23-10-2018 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 Pfam PF00682 HMGL-like 2 232 2.8E-41 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 Pfam PF00364 Biotin-requiring enzyme 524 589 4.7E-23 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 SUPERFAMILY SSF51569 2 299 8.06E-86 T 23-10-2018 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 SUPERFAMILY SSF51230 515 589 3.8E-25 T 23-10-2018 IPR011053 Single hybrid motif A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 Pfam PF02436 Conserved carboxylase domain 290 472 2.0E-57 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 546 563 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 Gene3D G3DSA:2.40.50.100 516 590 3.8E-29 T 23-10-2018 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 Gene3D G3DSA:3.20.20.70 1 455 9.5E-168 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_07315 9f953b0683ee621a5987bde4fd910f5e 590 SUPERFAMILY SSF89000 295 445 1.26E-53 T 23-10-2018 A3L12_02150 444d569ec7d31c4176722a96a67e967a 243 Pfam PF01381 Helix-turn-helix 28 75 6.9E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_02150 444d569ec7d31c4176722a96a67e967a 243 SMART SM00530 26 81 5.0E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_02150 444d569ec7d31c4176722a96a67e967a 243 SUPERFAMILY SSF47413 22 75 6.4E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_02150 444d569ec7d31c4176722a96a67e967a 243 Gene3D G3DSA:1.10.260.40 24 80 1.2E-10 T 23-10-2018 A3L12_02150 444d569ec7d31c4176722a96a67e967a 243 PIRSF PIRSF037724 1 237 7.6E-104 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 1.1E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 SUPERFAMILY SSF53748 2 398 3.89E-113 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 Gene3D G3DSA:3.40.50.1260 189 390 1.9E-135 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.425 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 PIRSF PIRSF000724 1 407 3.4E-128 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 Gene3D G3DSA:3.40.50.1260 9 397 1.9E-135 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_06930 1052d8521cb3c8c08e60b2f9545f588c 411 Pfam PF00162 Phosphoglycerate kinase 5 389 3.3E-105 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_00805 632105c546ec076340b070e327ff66cb 57 Gene3D G3DSA:3.90.940.50 1 57 6.8E-28 T 23-10-2018 A3L12_00805 632105c546ec076340b070e327ff66cb 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.618 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00805 632105c546ec076340b070e327ff66cb 57 Pfam PF01192 RNA polymerase Rpb6 5 51 4.5E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00805 632105c546ec076340b070e327ff66cb 57 PIRSF PIRSF000778 1 56 4.4E-23 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00805 632105c546ec076340b070e327ff66cb 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00805 632105c546ec076340b070e327ff66cb 57 SUPERFAMILY SSF63562 4 55 2.49E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 Pfam PF01472 PUA domain 511 565 2.1E-11 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 510 564 1.2E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 SUPERFAMILY SSF88802 249 498 2.35E-17 T 23-10-2018 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 Gene3D G3DSA:3.40.50.10630 252 422 5.9E-49 T 23-10-2018 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 SUPERFAMILY SSF52141 265 420 6.8E-42 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 SUPERFAMILY SSF88697 510 565 1.49E-13 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_04165 3aac75991e24464d00406251c6e7da90 567 Gene3D G3DSA:2.30.130.10 501 567 6.7E-25 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 SUPERFAMILY SSF51713 1 243 2.09E-19 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L12_04165 3aac75991e24464d00406251c6e7da90 567 SMART SM00359 501 567 1.3E-9 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 1.2E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 2.2E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 SUPERFAMILY SSF55021 53 133 2.17E-28 T 23-10-2018 A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 Gene3D G3DSA:1.10.1220.10 10 50 7.2E-21 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 SUPERFAMILY SSF47598 2 48 3.0E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 Gene3D G3DSA:3.30.70.1150 52 138 5.3E-37 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L12_01000 cfa811533fb4d25a96ed09f95df4e7cd 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.429 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 Gene3D G3DSA:3.30.360.20 182 276 1.9E-123 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 181 275 4.4E-26 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 SUPERFAMILY SSF52913 181 277 1.07E-25 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 11 326 1.9E-74 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 SUPERFAMILY SSF55205 4 215 4.25E-62 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 325 7.9E-124 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 PIRSF PIRSF005378 1 341 2.1E-109 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 Gene3D G3DSA:3.65.10.20 5 320 1.9E-123 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A3L12_00545 2d11c09da7aa838f5b05f97214cbbe71 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 39.208 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L12_02905 62674f07031d8da41bd18dd3e0040eee 387 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 6 373 4.5E-38 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 876 1.3E-10 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 880 13.436 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 SUPERFAMILY SSF75712 395 491 1.22E-17 T 23-10-2018 A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Gene3D G3DSA:3.40.50.300 678 882 4.5E-45 T 23-10-2018 A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Gene3D G3DSA:3.40.50.300 1 211 3.7E-47 T 23-10-2018 A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Gene3D G3DSA:1.10.287.510 392 506 1.3E-22 T 23-10-2018 A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 Pfam PF04423 Rad50 zinc hook motif 422 465 1.5E-13 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 SMART SM00382 22 873 0.0012 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03815 6328fe92b5362c61dfa8153cfc55230a 885 SUPERFAMILY SSF52540 1 870 2.5E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05600 67052f2ceb4dacdd72d24712cfbee6bc 197 SUPERFAMILY SSF48371 32 171 1.03E-11 T 23-10-2018 IPR016024 Armadillo-type fold A3L12_05600 67052f2ceb4dacdd72d24712cfbee6bc 197 Gene3D G3DSA:1.25.10.10 13 161 3.7E-8 T 23-10-2018 IPR011989 Armadillo-like helical A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 1.4E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 3.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 SUPERFAMILY SSF46924 1 63 8.11E-28 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 Gene3D G3DSA:1.10.10.60 1 65 6.4E-33 T 23-10-2018 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.804 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_00795 695ffc165fb21f6aee95f62540268fcf 65 PIRSF PIRSF005653 1 65 4.0E-32 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 174 1.3E-49 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 SUPERFAMILY SSF52972 1 174 3.27E-57 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 Gene3D G3DSA:3.90.950.10 1 179 2.3E-63 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 PIRSF PIRSF006305 1 182 5.3E-58 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 Pfam PF02545 Maf-like protein 2 174 3.4E-56 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L12_06655 4afc834e4cec60d502850c0ed613f999 185 Hamap MF_00528 Septum formation protein Maf [maf]. 1 182 31.576 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L12_04715 06cde59f4ca430399371e3b54d3d182d 162 Pfam PF01467 Cytidylyltransferase-like 8 144 7.7E-15 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_04715 06cde59f4ca430399371e3b54d3d182d 162 SUPERFAMILY SSF52374 2 146 2.56E-19 T 23-10-2018 A3L12_04715 06cde59f4ca430399371e3b54d3d182d 162 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 5 155 33.254 T 23-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A3L12_04715 06cde59f4ca430399371e3b54d3d182d 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 7 61 1.2E-11 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_04715 06cde59f4ca430399371e3b54d3d182d 162 Gene3D G3DSA:3.40.50.620 5 152 5.0E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03990 e8d9125e5e434c560f7674918338bcf0 342 Pfam PF13174 Tetratricopeptide repeat 159 182 0.0084 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_03990 e8d9125e5e434c560f7674918338bcf0 342 SUPERFAMILY SSF48452 130 327 1.2E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_03990 e8d9125e5e434c560f7674918338bcf0 342 Gene3D G3DSA:1.25.40.10 110 333 9.1E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_05000 5828b0737956e471736096f592e87b95 172 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 164 3.0E-31 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L12_05000 5828b0737956e471736096f592e87b95 172 Pfam PF01928 CYTH domain 2 160 7.7E-24 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L12_05000 5828b0737956e471736096f592e87b95 172 Gene3D G3DSA:2.40.320.10 1 170 1.0E-49 T 23-10-2018 A3L12_05000 5828b0737956e471736096f592e87b95 172 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 3.0E-44 T 23-10-2018 A3L12_05000 5828b0737956e471736096f592e87b95 172 SUPERFAMILY SSF55154 1 164 8.99E-40 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L12_05000 5828b0737956e471736096f592e87b95 172 SMART SM01118 1 166 2.1E-12 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 SMART SM00652 27 110 1.1E-41 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 17 109 7.9E-34 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 Gene3D G3DSA:2.40.50.140 9 119 4.8E-38 T 23-10-2018 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 SUPERFAMILY SSF50249 16 113 1.89E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 16 110 28.222 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 40 62 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 Pfam PF01176 Translation initiation factor 1A / IF-1 32 94 3.4E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A3L12_07915 1aba8d759d8a0244c643ec8f3fcb4236 121 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 52 109 3.0E-24 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L12_04690 27fb65bcd911f93ff087fd375a817e63 335 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 13 332 3.0E-60 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L12_04690 27fb65bcd911f93ff087fd375a817e63 335 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 321 2.4E-54 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 Gene3D G3DSA:3.40.50.7700 2 143 1.6E-62 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 26.195 T 23-10-2018 IPR033747 Class I PurE A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 SMART SM01001 1 143 5.7E-74 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 PIRSF PIRSF001338 1 143 1.4E-59 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 SUPERFAMILY SSF52255 1 141 8.37E-54 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 Pfam PF00731 AIR carboxylase 2 142 6.3E-57 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L12_03135 7b7a729ffc085f588cb5acba6b570f50 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 142 1.1E-55 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L12_02260 07a1f6ae6ca53a4938f32d23203e55aa 222 Pfam PF01987 Mitochondrial biogenesis AIM24 3 205 5.7E-63 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L12_02260 07a1f6ae6ca53a4938f32d23203e55aa 222 SUPERFAMILY SSF51219 1 221 1.65E-73 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A3L12_02260 07a1f6ae6ca53a4938f32d23203e55aa 222 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 220 4.5E-84 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L12_02260 07a1f6ae6ca53a4938f32d23203e55aa 222 Gene3D G3DSA:3.60.160.10 1 222 8.3E-82 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 SMART SM00729 27 231 0.0053 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 Pfam PF13353 4Fe-4S single cluster domain 34 119 3.0E-7 T 23-10-2018 A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 Pfam PF04055 Radical SAM superfamily 31 195 2.7E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 25 371 6.9E-151 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 Gene3D G3DSA:3.20.20.70 22 317 8.7E-45 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 SUPERFAMILY SSF102114 28 341 5.76E-53 T 23-10-2018 A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 Pfam PF13186 Iron-sulfur cluster-binding domain 258 336 1.2E-16 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 PIRSF PIRSF037420 22 223 1.5E-24 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L12_07455 5b1620ecb61c01b0290670af1bf29bf1 381 PIRSF PIRSF037420 287 362 2.6E-7 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L12_07830 363f8e5c893e88c4a948a79479ab900f 209 Gene3D G3DSA:3.90.320.10 2 207 6.7E-22 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L12_07830 363f8e5c893e88c4a948a79479ab900f 209 Pfam PF12705 PD-(D/E)XK nuclease superfamily 53 204 8.7E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L12_07830 363f8e5c893e88c4a948a79479ab900f 209 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 12 206 1.5E-25 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 SMART SM00322 146 211 8.1E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Gene3D G3DSA:2.40.50.100 1 57 1.1E-20 T 23-10-2018 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 SUPERFAMILY SSF110324 3 58 8.11E-14 T 23-10-2018 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 SMART SM00316 63 137 1.0E-6 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Gene3D G3DSA:3.30.1370.10 149 234 3.3E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 1.3E-6 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 40.027 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Pfam PF15985 KH domain 149 196 1.0E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 SUPERFAMILY SSF50249 59 152 2.29E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 Gene3D G3DSA:2.40.50.140 58 142 5.3E-20 T 23-10-2018 A3L12_00455 27114b2fc7108ed78eb71b49bc0e460f 254 SUPERFAMILY SSF54791 148 227 3.48E-17 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 SMART SM00418 56 130 1.7E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 Gene3D G3DSA:1.10.10.10 40 134 5.8E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 Pfam PF12840 Helix-turn-helix domain 56 111 3.1E-12 T 23-10-2018 A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 5.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 5.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_05155 3b43b9859e98ed191ae808fc91e683f8 136 SUPERFAMILY SSF46785 48 123 3.56E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01770 d91a62c63dd65c1edcae31dfa7628a13 399 PIRSF PIRSF000517 3 399 1.3E-78 T 23-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 A3L12_01770 d91a62c63dd65c1edcae31dfa7628a13 399 Gene3D G3DSA:3.40.640.10 53 294 8.7E-139 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_01770 d91a62c63dd65c1edcae31dfa7628a13 399 Gene3D G3DSA:3.90.1150.10 25 390 8.7E-139 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_01770 d91a62c63dd65c1edcae31dfa7628a13 399 Pfam PF00155 Aminotransferase class I and II 31 388 1.3E-56 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_01770 d91a62c63dd65c1edcae31dfa7628a13 399 SUPERFAMILY SSF53383 12 395 5.05E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_04675 5be102de8b59f7673823a1b2db853f59 299 SMART SM00769 165 282 4.9E-11 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L12_04675 5be102de8b59f7673823a1b2db853f59 299 Pfam PF03168 Late embryogenesis abundant protein 186 255 3.6E-10 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A3L12_04675 5be102de8b59f7673823a1b2db853f59 299 SUPERFAMILY SSF117070 160 265 2.09E-14 T 23-10-2018 A3L12_04675 5be102de8b59f7673823a1b2db853f59 299 Gene3D G3DSA:2.60.40.10 30 150 4.8E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_04675 5be102de8b59f7673823a1b2db853f59 299 Gene3D G3DSA:2.60.40.10 164 295 2.8E-27 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 Gene3D G3DSA:3.50.50.60 135 256 1.8E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 1.1E-38 T 23-10-2018 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.1E-38 T 23-10-2018 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 1.1E-38 T 23-10-2018 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.1E-38 T 23-10-2018 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 1.1E-38 T 23-10-2018 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 271 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 301 320 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 228 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 158 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 71 81 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 153 173 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 309 1.6E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 Gene3D G3DSA:3.50.50.60 18 314 1.8E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 19 320 1.7E-118 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A3L12_04550 d465d3beafb403c2dbc8c0de03927420 329 SUPERFAMILY SSF51905 16 319 8.19E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 SUPERFAMILY SSF56784 1 206 3.95E-50 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 185 6.7E-15 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 3.8E-32 T 23-10-2018 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 80 179 4.4E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 Gene3D G3DSA:1.10.150.520 15 86 1.8E-48 T 23-10-2018 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 4.3E-15 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 4.3E-15 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 4.3E-15 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 4.3E-15 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06315 b9a6fdd41b4bddd5a8e569dd8172a76e 214 Gene3D G3DSA:3.40.50.1000 2 206 1.8E-48 T 23-10-2018 IPR023214 HAD superfamily A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 Gene3D G3DSA:3.20.20.110 137 438 5.5E-124 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 1.4E-217 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 4.4E-46 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 SUPERFAMILY SSF51649 136 441 1.96E-105 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 Gene3D G3DSA:3.30.70.150 1 136 3.1E-46 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 SUPERFAMILY SSF54966 4 137 1.83E-39 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.466 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_01560 804843b41a44e7d019fe73d93c6774de 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 5.6E-94 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 24.936 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 1.0E-12 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 SUPERFAMILY SSF50249 3 69 6.43E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 Pfam PF01200 Ribosomal protein S28e 4 66 1.6E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07075 4b246631b3b68f891eca2b1edf07bddc 70 Gene3D G3DSA:2.40.50.140 1 70 3.7E-32 T 23-10-2018 A3L12_01320 ed2419b5df16d9981c31e13c96779531 239 PIRSF PIRSF006648 3 239 5.6E-22 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_01320 ed2419b5df16d9981c31e13c96779531 239 Pfam PF01061 ABC-2 type transporter 6 204 6.4E-25 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L12_05825 4bb0d325646f0b9acfed37e40e279923 116 Gene3D G3DSA:1.10.287.370 1 116 3.0E-39 T 23-10-2018 IPR009053 Prefoldin A3L12_05825 4bb0d325646f0b9acfed37e40e279923 116 SUPERFAMILY SSF46579 6 110 4.97E-23 T 23-10-2018 A3L12_05825 4bb0d325646f0b9acfed37e40e279923 116 Pfam PF01920 Prefoldin subunit 9 111 2.1E-24 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L12_05825 4bb0d325646f0b9acfed37e40e279923 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 48.172 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L12_05825 4bb0d325646f0b9acfed37e40e279923 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 8.6E-39 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L12_07110 f0ccdd68f43b662f3b80c706351a779a 99 Pfam PF11505 Protein of unknown function (DUF3216) 8 97 4.5E-29 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A3L12_07110 f0ccdd68f43b662f3b80c706351a779a 99 Gene3D G3DSA:1.20.120.460 3 99 4.9E-29 T 23-10-2018 IPR038317 Pf1176-like superfamily A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 Gene3D G3DSA:3.40.50.300 223 374 3.4E-29 T 23-10-2018 A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 SUPERFAMILY SSF52540 28 349 1.06E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 Pfam PF00270 DEAD/DEAH box helicase 18 182 1.8E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 Pfam PF08494 DEAD/H associated 583 750 3.7E-16 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 Gene3D G3DSA:3.40.50.300 4 200 1.4E-45 T 23-10-2018 A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 SMART SM00490 259 341 3.2E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 SMART SM00487 12 210 3.6E-35 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_07155 0aa0e613a6e4f7ed9301007372c86955 926 Pfam PF00271 Helicase conserved C-terminal domain 238 337 3.9E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 Gene3D G3DSA:3.10.440.10 3 89 6.8E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 12 57 1.0E-17 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 89 21.865 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 SUPERFAMILY SSF54575 6 83 1.7E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 ProSitePatterns PS01144 Ribosomal protein L31e signature. 47 61 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 SMART SM01380 7 81 1.6E-19 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06525 932a83471afa414c15cd3034e4cb318f 89 Pfam PF01198 Ribosomal protein L31e 12 77 1.4E-9 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Pfam PF13718 GNAT acetyltransferase 2 499 615 6.3E-33 T 23-10-2018 IPR000182 GNAT domain A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Gene3D G3DSA:3.40.630.30 456 662 8.4E-54 T 23-10-2018 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Gene3D G3DSA:3.40.50.11040 25 244 1.6E-9 T 23-10-2018 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 47.08 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 SUPERFAMILY SSF55729 503 644 4.37E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 1.9E-31 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 SUPERFAMILY SSF52540 259 397 3.64E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Gene3D G3DSA:3.40.50.12320 281 448 5.1E-34 T 23-10-2018 A3L12_07020 f4af69b43a73ae5fb97e014a02031e4f 813 Pfam PF05127 Helicase 285 458 2.1E-54 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 1.4E-170 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 Gene3D G3DSA:3.40.1380.20 337 474 3.4E-168 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 SUPERFAMILY SSF50800 75 166 5.06E-23 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 SUPERFAMILY SSF51621 4 339 2.27E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 Gene3D G3DSA:3.20.20.60 7 336 3.4E-168 T 23-10-2018 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 SUPERFAMILY SSF52935 324 478 2.75E-33 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 9.3E-66 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 2.3E-24 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 2.7E-119 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_07995 ff8dc8655b6b1267140131ac6af51ced 478 Gene3D G3DSA:2.40.33.10 74 170 3.4E-168 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L12_05690 237f4cb33ea34beb214c1d2f332f0c28 619 Pfam PF00361 Proton-conducting membrane transporter 118 425 1.4E-58 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_00735 7ac02183b45e366722cc67c76feed88f 83 Pfam PF01929 Ribosomal protein L14 44 81 1.1E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00735 7ac02183b45e366722cc67c76feed88f 83 SUPERFAMILY SSF50104 2 80 3.01E-19 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_00735 7ac02183b45e366722cc67c76feed88f 83 Gene3D G3DSA:2.30.30.30 2 83 2.9E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_00735 7ac02183b45e366722cc67c76feed88f 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.676 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A3L12_03350 13f8933854d6a47c7ef5f3771229f0b2 220 Pfam PF00149 Calcineurin-like phosphoesterase 17 110 3.1E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_03350 13f8933854d6a47c7ef5f3771229f0b2 220 SUPERFAMILY SSF56300 17 154 2.35E-17 T 23-10-2018 A3L12_03350 13f8933854d6a47c7ef5f3771229f0b2 220 Gene3D G3DSA:3.60.21.10 12 115 1.2E-12 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_03350 13f8933854d6a47c7ef5f3771229f0b2 220 PIRSF PIRSF000887 4 215 3.9E-40 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Gene3D G3DSA:3.30.420.40 9 312 4.9E-61 T 23-10-2018 A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Gene3D G3DSA:3.30.420.350 95 305 4.9E-61 T 23-10-2018 A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Gene3D G3DSA:3.90.870.20 330 535 1.9E-71 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Pfam PF16861 Carbamoyltransferase C-terminus 368 535 4.9E-60 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 SUPERFAMILY SSF53067 10 313 1.04E-10 T 23-10-2018 A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Pfam PF02543 Carbamoyltransferase N-terminus 2 65 5.8E-8 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L12_05390 21b2122541af8645408ddf7c2985df9f 537 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 7.0E-34 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 SUPERFAMILY SSF56300 401 629 1.23E-18 T 23-10-2018 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 657 32.513 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 Gene3D G3DSA:3.60.21.50 385 642 2.9E-23 T 23-10-2018 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 PIRSF PIRSF000803 86 664 1.6E-176 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 Gene3D G3DSA:2.40.50.140 304 373 3.1E-5 T 23-10-2018 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 402 602 5.2E-15 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 A3L12_04740 88fa4178289a272701e5c0f21ef0bff8 667 Gene3D G3DSA:1.10.8.800 2 68 4.2E-22 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Gene3D G3DSA:1.10.10.1100 398 474 5.5E-145 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Gene3D G3DSA:3.50.50.60 219 309 5.5E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Gene3D G3DSA:3.10.20.440 1 94 3.3E-37 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Gene3D G3DSA:3.50.50.60 109 480 5.5E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 317 3.9E-7 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 207 225 3.9E-7 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 129 3.9E-7 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 109 256 1.2E-12 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 SUPERFAMILY SSF51905 104 277 7.34E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 12 87 6.4E-15 T 23-10-2018 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 131 3.9E-5 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_02355 1c9ddf96d3b1051a02c5e110fb084ca4 497 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 208 216 3.9E-5 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_07625 94ddef338644522830f93db27b6a969c 110 PIRSF PIRSF005586 1 110 1.3E-38 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A3L12_07625 94ddef338644522830f93db27b6a969c 110 Gene3D G3DSA:2.20.25.10 56 110 3.0E-27 T 23-10-2018 A3L12_07625 94ddef338644522830f93db27b6a969c 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 2.2E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L12_07625 94ddef338644522830f93db27b6a969c 110 SMART SM00440 69 108 1.9E-23 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L12_07625 94ddef338644522830f93db27b6a969c 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L12_07625 94ddef338644522830f93db27b6a969c 110 SUPERFAMILY SSF57783 48 109 2.21E-23 T 23-10-2018 A3L12_07625 94ddef338644522830f93db27b6a969c 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 1.2E-37 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A3L12_07625 94ddef338644522830f93db27b6a969c 110 SMART SM00661 2 56 6.7E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L12_07625 94ddef338644522830f93db27b6a969c 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A3L12_07625 94ddef338644522830f93db27b6a969c 110 SUPERFAMILY SSF57783 1 35 1.96E-6 T 23-10-2018 A3L12_07625 94ddef338644522830f93db27b6a969c 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 7.9E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 Pfam PF13360 PQQ-like domain 216 402 1.1E-9 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SUPERFAMILY SSF50998 73 403 1.33E-14 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 Gene3D G3DSA:2.130.10.10 20 410 6.0E-18 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SMART SM00564 327 374 280.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SMART SM00564 245 279 68.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SMART SM00564 62 90 130.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SMART SM00564 197 237 0.8 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L12_07515 d41d966553bbec9b74978a0c40ebb184 431 SMART SM00564 286 320 160.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L12_06035 5c4926656be849d65ac3fd2cbf0a4945 97 Gene3D G3DSA:2.20.28.10 1 97 8.0E-33 T 23-10-2018 A3L12_06035 5c4926656be849d65ac3fd2cbf0a4945 97 SUPERFAMILY SSF46785 2 96 1.71E-33 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 Gene3D G3DSA:3.40.50.720 6 140 9.7E-44 T 23-10-2018 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 SUPERFAMILY SSF52210 143 304 5.76E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 Gene3D G3DSA:3.40.50.261 310 471 1.1E-48 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 SMART SM00881 12 111 4.4E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 SUPERFAMILY SSF52210 311 468 2.09E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 Pfam PF13380 CoA binding domain 16 145 6.8E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 SUPERFAMILY SSF51735 10 141 3.54E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 Gene3D G3DSA:3.40.50.261 142 306 7.2E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_06900 58c4c8ce7565de4a4785e3dcd1616367 471 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 5.4E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 SUPERFAMILY SSF52540 2 225 2.38E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 SMART SM00382 26 217 4.8E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 Gene3D G3DSA:3.40.50.300 1 241 1.7E-57 T 23-10-2018 A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 Pfam PF00005 ABC transporter 17 167 3.3E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07595 e865ea38b22c8d70fe0f869fd929a5b1 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 237 7.0E-88 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A3L12_02050 95b118e37a2a73b1e8b340ff6b5ba6df 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 3.4E-22 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_02050 95b118e37a2a73b1e8b340ff6b5ba6df 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 157 8.8E-32 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L12_02050 95b118e37a2a73b1e8b340ff6b5ba6df 164 Gene3D G3DSA:3.60.21.10 1 163 2.3E-36 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_02050 95b118e37a2a73b1e8b340ff6b5ba6df 164 SUPERFAMILY SSF56300 2 162 3.32E-33 T 23-10-2018 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 Gene3D G3DSA:3.40.50.1860 3 215 1.5E-73 T 23-10-2018 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 6.7E-52 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 225 1.6E-52 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 SUPERFAMILY SSF53681 116 225 4.36E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 SUPERFAMILY SSF53681 1 114 3.05E-28 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_08055 66ef283d47a4efb4559710bdb35dc90d 227 Gene3D G3DSA:3.40.50.1860 102 211 1.5E-73 T 23-10-2018 A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 Pfam PF00271 Helicase conserved C-terminal domain 245 348 8.7E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 Gene3D G3DSA:3.40.50.300 215 425 1.1E-16 T 23-10-2018 A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 39 379 3.2E-85 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 SMART SM00487 17 229 7.4E-11 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 Gene3D G3DSA:3.40.50.300 18 214 1.8E-14 T 23-10-2018 A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 Pfam PF04851 Type III restriction enzyme, res subunit 33 196 7.1E-8 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 SMART SM00490 268 348 3.3E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06430 f6aa863d826c29f7b044e1aa7ee40e2e 519 SUPERFAMILY SSF52540 35 361 1.77E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02025 76e47f984d25ca5772f00a900b2d75af 339 Pfam PF00466 Ribosomal protein L10 5 105 5.1E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A3L12_02025 76e47f984d25ca5772f00a900b2d75af 339 SUPERFAMILY SSF160369 5 141 1.83E-22 T 23-10-2018 A3L12_02025 76e47f984d25ca5772f00a900b2d75af 339 Gene3D G3DSA:3.30.70.1730 15 211 1.5E-72 T 23-10-2018 A3L12_02025 76e47f984d25ca5772f00a900b2d75af 339 Gene3D G3DSA:3.90.105.20 107 186 1.5E-72 T 23-10-2018 A3L12_02025 76e47f984d25ca5772f00a900b2d75af 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 35.822 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 Pfam PF02926 THUMP domain 31 182 7.6E-26 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 SUPERFAMILY SSF53335 177 359 2.2E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 Gene3D G3DSA:3.30.2130.30 1 189 1.3E-78 T 23-10-2018 A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 SMART SM00981 86 182 5.5E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 SUPERFAMILY SSF143437 98 182 6.28E-11 T 23-10-2018 A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 6.2E-33 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L12_00080 015eb34c2f207025353fa13a9ea4709b 365 Gene3D G3DSA:3.40.50.150 190 365 1.0E-47 T 23-10-2018 A3L12_01150 87852a9b112051b321ae8db21f68bd29 137 Hamap MF_01112 UPF0201 protein . 5 134 24.819 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L12_01150 87852a9b112051b321ae8db21f68bd29 137 Pfam PF01877 RNA binding 6 115 1.7E-18 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L12_01150 87852a9b112051b321ae8db21f68bd29 137 SUPERFAMILY SSF55282 6 136 7.65E-39 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01150 87852a9b112051b321ae8db21f68bd29 137 Gene3D G3DSA:3.30.1440.10 1 136 1.6E-42 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 SUPERFAMILY SSF52343 89 256 4.65E-16 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 Gene3D G3DSA:2.40.30.10 1 92 2.2E-18 T 23-10-2018 A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 SUPERFAMILY SSF63380 2 93 7.03E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 PIRSF PIRSF006816 1 263 2.4E-64 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 Gene3D G3DSA:3.40.50.80 100 211 2.9E-24 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_01220 50d0b4e935eccfa3a07e378f0d5efce4 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 256 1.3E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L12_01185 c2d25d5c879dd460929a88eda2faacab 392 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 44 98 4.2E-6 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L12_01185 c2d25d5c879dd460929a88eda2faacab 392 Gene3D G3DSA:1.10.3720.10 132 373 8.8E-29 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01185 c2d25d5c879dd460929a88eda2faacab 392 SUPERFAMILY SSF161098 137 355 8.76E-31 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01185 c2d25d5c879dd460929a88eda2faacab 392 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 375 1.1E-32 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 SUPERFAMILY SSF53092 2 129 1.92E-17 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 131 1.5E-19 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 Pfam PF00557 Metallopeptidase family M24 139 339 6.3E-69 T 23-10-2018 IPR000994 Peptidase M24 A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 SUPERFAMILY SSF55920 130 356 6.8E-77 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 Gene3D G3DSA:3.90.230.10 131 356 1.7E-82 T 23-10-2018 A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L12_00970 fa83192f4eb96d9639bb83d800eb5086 356 Gene3D G3DSA:3.40.350.10 1 129 5.7E-33 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 Pfam PF00344 SecY translocase 72 460 2.7E-70 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 SUPERFAMILY SSF103491 9 467 2.88E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 476 20.045 T 23-10-2018 IPR026593 Protein translocase subunit SecY A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 PIRSF PIRSF004557 5 481 3.3E-101 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 Gene3D G3DSA:1.10.3370.10 26 481 4.2E-177 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 469 4.3E-91 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 445 463 3.1E-6 T 23-10-2018 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 3.1E-6 T 23-10-2018 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 3.1E-6 T 23-10-2018 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 Pfam PF10559 Plug domain of Sec61p 38 71 2.6E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_00710 c8ff451850d6fac788e2085e086d3542 481 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Gene3D G3DSA:3.30.1360.30 270 400 1.1E-50 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 625 330.835 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Pfam PF02934 GatB/GatE catalytic domain 9 440 1.6E-65 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 SUPERFAMILY SSF89095 478 620 7.19E-28 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Gene3D G3DSA:1.10.10.410 562 620 3.9E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 173 187 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Gene3D G3DSA:1.10.150.380 449 542 9.2E-24 T 23-10-2018 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Pfam PF02938 GAD domain 294 386 8.7E-18 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 SUPERFAMILY SSF55931 2 449 1.5E-100 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 Pfam PF02637 GatB domain 481 620 1.2E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 SUPERFAMILY SSF55261 275 400 6.38E-44 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 1 623 9.4E-239 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 SMART SM00845 480 620 3.7E-38 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L12_06045 1767ede5bbf2aa734fa90143c9cf689b 625 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 278 402 1.0E-50 T 23-10-2018 A3L12_01850 1eac8b0fe8bb07bf8194b2161f4533f4 221 Pfam PF01963 TraB family 156 216 1.2E-7 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A3L12_08000 04c13e904c22fc140f3cd7c5e291b6e9 159 PIRSF PIRSF000239 4 159 3.7E-21 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L12_08000 04c13e904c22fc140f3cd7c5e291b6e9 159 SUPERFAMILY SSF52833 6 149 6.01E-42 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L12_08000 04c13e904c22fc140f3cd7c5e291b6e9 159 Gene3D G3DSA:3.40.30.10 2 150 5.6E-42 T 23-10-2018 A3L12_08000 04c13e904c22fc140f3cd7c5e291b6e9 159 Pfam PF00578 AhpC/TSA family 7 128 2.9E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L12_04515 38465f4f140d20401aaf7eb1dae58f54 431 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 47 72 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L12_04515 38465f4f140d20401aaf7eb1dae58f54 431 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 380 1.1E-59 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04515 38465f4f140d20401aaf7eb1dae58f54 431 SUPERFAMILY SSF56762 18 380 5.63E-103 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04515 38465f4f140d20401aaf7eb1dae58f54 431 Pfam PF00374 Nickel-dependent hydrogenase 47 114 1.3E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L12_04515 38465f4f140d20401aaf7eb1dae58f54 431 Gene3D G3DSA:1.10.645.20 9 380 1.9E-122 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_03660 44d20a28d247e68fbe5ea4e70d571199 249 Gene3D G3DSA:3.30.70.1890 1 121 3.4E-41 T 23-10-2018 A3L12_03660 44d20a28d247e68fbe5ea4e70d571199 249 Gene3D G3DSA:3.30.70.1900 122 242 5.0E-36 T 23-10-2018 A3L12_03660 44d20a28d247e68fbe5ea4e70d571199 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 4.8E-42 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_03660 44d20a28d247e68fbe5ea4e70d571199 249 Pfam PF01881 CRISPR associated protein Cas6 95 237 1.4E-31 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_03660 44d20a28d247e68fbe5ea4e70d571199 249 PIRSF PIRSF005054 1 242 6.2E-62 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_05485 e003cdd186c953c4d53228f4e83c7198 427 Gene3D G3DSA:1.10.645.10 6 423 2.3E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05485 e003cdd186c953c4d53228f4e83c7198 427 SUPERFAMILY SSF56762 8 423 2.49E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05485 e003cdd186c953c4d53228f4e83c7198 427 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 414 423 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L12_05485 e003cdd186c953c4d53228f4e83c7198 427 Pfam PF00374 Nickel-dependent hydrogenase 43 121 1.3E-11 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L12_05485 e003cdd186c953c4d53228f4e83c7198 427 Pfam PF00374 Nickel-dependent hydrogenase 216 423 1.2E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L12_02600 065c56f4e2c7a94df74c3dda95d053fb 250 Pfam PF05971 Protein of unknown function (DUF890) 82 164 1.0E-5 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A3L12_02600 065c56f4e2c7a94df74c3dda95d053fb 250 SUPERFAMILY SSF53335 8 233 4.03E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_02600 065c56f4e2c7a94df74c3dda95d053fb 250 Gene3D G3DSA:3.40.50.150 66 249 7.6E-38 T 23-10-2018 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 PIRSF PIRSF002133 19 147 1.7E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.994 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01735 5246d79370499f0a6bec68e7d785e5d4 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 23-10-2018 A3L12_07025 95d9a832186615fbbe3063a3b02f68a3 168 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 5.0E-28 T 23-10-2018 A3L12_07025 95d9a832186615fbbe3063a3b02f68a3 168 Pfam PF01936 NYN domain 32 163 8.7E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L12_07025 95d9a832186615fbbe3063a3b02f68a3 168 Gene3D G3DSA:3.40.50.1010 24 166 1.2E-8 T 23-10-2018 A3L12_07025 95d9a832186615fbbe3063a3b02f68a3 168 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 166 3.2E-61 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 PIRSF PIRSF003092 1 259 1.0E-64 T 23-10-2018 IPR025501 ATP binding protein MinD A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 SMART SM00382 3 163 0.0028 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.0E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 6.6E-24 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 SUPERFAMILY SSF52540 3 236 1.82E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06735 57b81f1bd0ec8328ccbb3b11aee3cabe 259 Gene3D G3DSA:3.40.50.300 4 233 3.8E-67 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 SUPERFAMILY SSF52009 353 461 2.22E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Gene3D G3DSA:3.20.20.60 462 783 3.2E-103 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 511 530 1.3E-12 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 728 740 1.3E-12 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 675 690 1.3E-12 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 692 707 1.3E-12 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 351 7.9E-118 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 472 768 3.0E-93 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 2.7E-27 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 770 3.4E-287 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 SUPERFAMILY SSF56059 4 381 5.42E-106 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Gene3D G3DSA:3.30.1490.20 3 197 5.3E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 PIRSF PIRSF000854 1 774 1.4E-205 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 SUPERFAMILY SSF51621 484 777 1.99E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 675 693 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Gene3D G3DSA:3.50.30.10 355 461 5.6E-44 T 23-10-2018 A3L12_01100 f4d343add1c2afa04e056bad12b5aa32 783 Gene3D G3DSA:3.30.470.20 198 354 3.3E-53 T 23-10-2018 A3L12_05205 d4037201945336b524350935f5ca098a 234 PRINTS PR01874 DNA repair protein radA signature 15 43 1.6E-9 T 23-10-2018 A3L12_05205 d4037201945336b524350935f5ca098a 234 PRINTS PR01874 DNA repair protein radA signature 57 74 1.6E-9 T 23-10-2018 A3L12_05205 d4037201945336b524350935f5ca098a 234 SUPERFAMILY SSF52540 4 228 3.51E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05205 d4037201945336b524350935f5ca098a 234 Pfam PF06745 KaiC 6 228 5.2E-48 T 23-10-2018 IPR014774 KaiC-like domain A3L12_05205 d4037201945336b524350935f5ca098a 234 Gene3D G3DSA:3.40.50.300 1 230 1.9E-55 T 23-10-2018 A3L12_04005 831ade1d427318a577ea29782961736f 442 Pfam PF01926 50S ribosome-binding GTPase 188 307 4.4E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 Hamap MF_00900 GTPase HflX [hflX]. 17 391 41.627 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 Gene3D G3DSA:3.40.50.300 187 363 2.0E-43 T 23-10-2018 A3L12_04005 831ade1d427318a577ea29782961736f 442 SUPERFAMILY SSF52540 188 362 8.8E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04005 831ade1d427318a577ea29782961736f 442 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 7.5E-18 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A3L12_04005 831ade1d427318a577ea29782961736f 442 Gene3D G3DSA:3.40.50.11060 11 129 1.4E-33 T 23-10-2018 A3L12_04005 831ade1d427318a577ea29782961736f 442 Pfam PF13167 GTP-binding GTPase N-terminal 18 100 1.6E-23 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A3L12_04005 831ade1d427318a577ea29782961736f 442 PIRSF PIRSF006809 1 422 1.1E-119 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 344 4.0E-94 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 328 1.3E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 3.6E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04005 831ade1d427318a577ea29782961736f 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 3.6E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_01670 66206652f08b9ff8f4a77ded9933e96b 502 Pfam PF02347 Glycine cleavage system P-protein 34 310 1.7E-9 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L12_01670 66206652f08b9ff8f4a77ded9933e96b 502 SUPERFAMILY SSF53383 12 488 2.29E-125 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_01670 66206652f08b9ff8f4a77ded9933e96b 502 Gene3D G3DSA:3.40.640.10 86 315 4.5E-60 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_01670 66206652f08b9ff8f4a77ded9933e96b 502 Gene3D G3DSA:3.90.1150.10 341 475 4.5E-43 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_01670 66206652f08b9ff8f4a77ded9933e96b 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 61.558 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A3L12_06920 a64feca1b39c54ee46060b44441da562 322 SUPERFAMILY SSF52540 3 224 1.38E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06920 a64feca1b39c54ee46060b44441da562 322 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_06920 a64feca1b39c54ee46060b44441da562 322 SMART SM00382 28 212 3.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06920 a64feca1b39c54ee46060b44441da562 322 Pfam PF13732 Domain of unknown function (DUF4162) 217 303 2.8E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L12_06920 a64feca1b39c54ee46060b44441da562 322 Pfam PF00005 ABC transporter 20 162 1.6E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06920 a64feca1b39c54ee46060b44441da562 322 Gene3D G3DSA:3.40.50.300 1 232 7.4E-76 T 23-10-2018 A3L12_06920 a64feca1b39c54ee46060b44441da562 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 305 3.5E-122 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L12_02005 7f696de2965d692bfca8469aa27089ed 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_02005 7f696de2965d692bfca8469aa27089ed 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 4 60 7.4E-18 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_02005 7f696de2965d692bfca8469aa27089ed 61 SUPERFAMILY SSF103456 3 58 6.41E-19 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_02005 7f696de2965d692bfca8469aa27089ed 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.044 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_02005 7f696de2965d692bfca8469aa27089ed 61 Gene3D G3DSA:1.20.5.820 1 61 3.2E-22 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_05250 b77fb312c79b3d885504e2a4ef3fb7c3 332 SUPERFAMILY SSF53807 30 294 7.85E-44 T 23-10-2018 A3L12_05250 b77fb312c79b3d885504e2a4ef3fb7c3 332 Pfam PF01297 Zinc-uptake complex component A periplasmic 34 271 5.3E-34 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A3L12_05250 b77fb312c79b3d885504e2a4ef3fb7c3 332 Gene3D G3DSA:3.40.50.1980 30 193 2.0E-30 T 23-10-2018 A3L12_08030 bda1da1656816f49c17a339615ec28ae 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.349 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L12_08030 bda1da1656816f49c17a339615ec28ae 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 5.9E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L12_08030 bda1da1656816f49c17a339615ec28ae 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 5.2E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 Gene3D G3DSA:3.40.50.720 3 354 8.4E-130 T 23-10-2018 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 Gene3D G3DSA:3.30.360.10 216 319 8.4E-130 T 23-10-2018 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 SUPERFAMILY SSF55347 211 316 1.31E-28 T 23-10-2018 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 SUPERFAMILY SSF51735 1 379 3.74E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 120 211 3.3E-7 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 4.1E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L12_02085 d1d9c7e25cca4dc15a8841ad6f7c8931 382 PIRSF PIRSF015578 1 379 3.7E-93 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 PIRSF PIRSF000164 1 300 5.0E-86 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 Gene3D G3DSA:3.20.20.70 12 289 2.8E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 SUPERFAMILY SSF51395 3 298 5.33E-81 T 23-10-2018 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 2.6E-125 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 2.9E-61 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.225 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A3L12_01370 0864589831cea52ea1a66f41107b290d 301 Gene3D G3DSA:2.30.26.10 55 212 2.8E-91 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A3L12_07115 9a9c77d5267ea7943f5e16c3120fd9c8 254 SUPERFAMILY SSF51556 1 251 5.87E-59 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L12_07115 9a9c77d5267ea7943f5e16c3120fd9c8 254 Gene3D G3DSA:3.20.20.140 1 251 2.4E-65 T 23-10-2018 A3L12_07115 9a9c77d5267ea7943f5e16c3120fd9c8 254 PIRSF PIRSF005902 1 253 1.1E-58 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L12_07115 9a9c77d5267ea7943f5e16c3120fd9c8 254 Pfam PF01026 TatD related DNase 2 248 1.5E-59 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L12_07115 9a9c77d5267ea7943f5e16c3120fd9c8 254 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 1.2E-69 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 393 411 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 447 466 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 528 543 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 419 443 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 473 493 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 546 568 1.8E-48 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 Pfam PF00326 Prolyl oligopeptidase family 410 612 5.3E-53 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 Gene3D G3DSA:3.40.50.1820 2 608 2.1E-132 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 SUPERFAMILY SSF50993 2 364 1.46E-39 T 23-10-2018 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 SUPERFAMILY SSF53474 366 612 4.5E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 357 2.1E-17 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A3L12_05210 89038628bb97069dd08a6fee36b821e6 612 Gene3D G3DSA:2.130.10.120 49 360 2.1E-132 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 Gene3D G3DSA:3.40.50.300 160 318 2.3E-42 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 Gene3D G3DSA:3.40.50.300 18 132 1.5E-30 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 568 586 2.4E-29 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 438 454 2.4E-29 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 545 564 2.4E-29 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 65 84 2.4E-29 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 515 534 2.4E-29 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 22 627 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A3L12_05495 71893c785a6545efc7240354e1699eac 633 Gene3D G3DSA:3.30.230.10 430 633 1.4E-78 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_05495 71893c785a6545efc7240354e1699eac 633 SUPERFAMILY SSF52540 34 412 1.19E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05495 71893c785a6545efc7240354e1699eac 633 Pfam PF01078 Magnesium chelatase, subunit ChlI 39 91 3.2E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain A3L12_05495 71893c785a6545efc7240354e1699eac 633 Gene3D G3DSA:1.10.8.60 319 411 4.1E-44 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 Pfam PF13654 AAA domain 181 409 5.9E-23 T 23-10-2018 A3L12_05495 71893c785a6545efc7240354e1699eac 633 SMART SM00382 57 320 1.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_05495 71893c785a6545efc7240354e1699eac 633 SUPERFAMILY SSF54211 438 611 5.31E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_05495 71893c785a6545efc7240354e1699eac 633 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 432 613 3.5E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 8.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 8.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 8.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 8.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 Pfam PF02163 Peptidase family M50 115 292 1.7E-11 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 SUPERFAMILY SSF50156 203 292 5.65E-24 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 SMART SM00228 190 263 2.0E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 Gene3D G3DSA:2.30.42.10 203 290 5.5E-24 T 23-10-2018 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 Pfam PF02163 Peptidase family M50 305 364 1.6E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_00190 853be3401e065ccc346c21dc7c384be2 377 Pfam PF13180 PDZ domain 205 272 1.1E-14 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 425 431 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 Pfam PF07669 Eco57I restriction-modification methylase 422 560 2.5E-9 T 23-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 422 434 3.1E-16 T 23-10-2018 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 143 159 3.1E-16 T 23-10-2018 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 204 218 3.1E-16 T 23-10-2018 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 489 513 3.1E-16 T 23-10-2018 A3L12_05725 ab2845d11b231c4c1ad0c989902b0d8f 1005 SUPERFAMILY SSF53335 53 585 2.04E-56 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_04565 a79f181a638556984379fe6c3c722ebc 97 Pfam PF08967 Domain of unknown function (DUF1884) 5 81 2.6E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L12_04565 a79f181a638556984379fe6c3c722ebc 97 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 7 79 1.0E-20 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L12_04565 a79f181a638556984379fe6c3c722ebc 97 Gene3D G3DSA:3.30.2320.10 3 80 2.3E-20 T 23-10-2018 A3L12_04565 a79f181a638556984379fe6c3c722ebc 97 PIRSF PIRSF004604 3 96 4.5E-30 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L12_04565 a79f181a638556984379fe6c3c722ebc 97 SUPERFAMILY SSF111057 6 79 1.22E-22 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L12_02950 8301c755c02d4bf95fe7a3de3c2d098b 362 Gene3D G3DSA:3.40.50.2000 187 345 1.1E-19 T 23-10-2018 A3L12_02950 8301c755c02d4bf95fe7a3de3c2d098b 362 Gene3D G3DSA:3.40.50.2000 15 186 3.0E-25 T 23-10-2018 A3L12_02950 8301c755c02d4bf95fe7a3de3c2d098b 362 Pfam PF13524 Glycosyl transferases group 1 276 351 1.7E-10 T 23-10-2018 A3L12_02950 8301c755c02d4bf95fe7a3de3c2d098b 362 Pfam PF13439 Glycosyltransferase Family 4 17 177 1.1E-20 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L12_02950 8301c755c02d4bf95fe7a3de3c2d098b 362 SUPERFAMILY SSF53756 18 359 1.02E-50 T 23-10-2018 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 Gene3D G3DSA:3.40.50.620 164 373 1.5E-89 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 1.5E-117 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 SUPERFAMILY SSF52374 164 372 1.13E-76 T 23-10-2018 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 SUPERFAMILY SSF88697 5 157 5.57E-48 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.269 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 Pfam PF01747 ATP-sulfurylase 164 372 3.5E-86 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 Pfam PF14306 PUA-like domain 4 156 5.7E-50 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L12_02895 25fdb6041a805f9071d36e58de1c7524 379 Gene3D G3DSA:3.10.400.10 1 159 3.7E-48 T 23-10-2018 A3L12_06520 406b577ceea25ca1eca74cece6418e06 51 SUPERFAMILY SSF48662 4 50 4.97E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L12_06520 406b577ceea25ca1eca74cece6418e06 51 Pfam PF00832 Ribosomal L39 protein 9 50 2.7E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_06520 406b577ceea25ca1eca74cece6418e06 51 Gene3D G3DSA:1.10.1620.10 2 51 1.6E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L12_06520 406b577ceea25ca1eca74cece6418e06 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 18.546 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 Gene3D G3DSA:3.60.9.10 1 223 5.4E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 237 607 3.8E-79 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 Gene3D G3DSA:1.10.599.10 251 607 2.3E-76 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 218 4.2E-63 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 SMART SM00790 4 220 8.4E-96 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 SUPERFAMILY SSF56228 1 222 5.1E-60 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 SUPERFAMILY SSF48310 225 609 1.09E-87 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_02705 d112f8f13f32eb68c8c9630bb231f633 623 Gene3D G3DSA:1.10.569.10 252 446 2.3E-76 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 Gene3D G3DSA:3.40.50.261 290 457 2.6E-63 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 SMART SM00881 6 100 6.5E-29 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 SUPERFAMILY SSF52210 292 450 2.09E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 SUPERFAMILY SSF51735 3 130 1.58E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 SUPERFAMILY SSF52210 132 288 2.75E-46 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 Gene3D G3DSA:3.40.50.261 130 289 6.8E-62 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 Pfam PF13380 CoA binding domain 12 135 3.1E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 Gene3D G3DSA:3.40.50.720 3 129 3.7E-43 T 23-10-2018 A3L12_02205 bf868e4480226cd4ea84faa3290676e5 457 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 6.8E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L12_00185 fbd2544f9d68970b4a69c16f52874ef6 323 SUPERFAMILY SSF52402 25 257 7.06E-55 T 23-10-2018 A3L12_00185 fbd2544f9d68970b4a69c16f52874ef6 323 Pfam PF01171 PP-loop family 50 228 6.6E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L12_00185 fbd2544f9d68970b4a69c16f52874ef6 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 3.4E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L12_00185 fbd2544f9d68970b4a69c16f52874ef6 323 Gene3D G3DSA:3.40.50.620 1 318 1.3E-87 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_00185 fbd2544f9d68970b4a69c16f52874ef6 323 PIRSF PIRSF004976 1 317 1.5E-112 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L12_01990 46e0e89703573be706010e1422a7185c 402 SUPERFAMILY SSF53743 1 280 8.89E-36 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L12_08070 2e01d22914bae4aee931b6af32e9e643 472 SUPERFAMILY SSF111283 2 467 2.09E-103 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L12_08070 2e01d22914bae4aee931b6af32e9e643 472 PIRSF PIRSF004919 1 471 1.1E-149 T 23-10-2018 IPR025502 TldD A3L12_08070 2e01d22914bae4aee931b6af32e9e643 472 Pfam PF01523 Putative modulator of DNA gyrase 18 324 2.7E-57 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L12_08070 2e01d22914bae4aee931b6af32e9e643 472 Gene3D G3DSA:3.30.2290.10 1 194 3.8E-25 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L12_04695 e8b4b7ad663faa4c2d5f45b240d79c21 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 29.967 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L12_04695 e8b4b7ad663faa4c2d5f45b240d79c21 278 Gene3D G3DSA:2.60.200.30 121 254 3.6E-71 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L12_04695 e8b4b7ad663faa4c2d5f45b240d79c21 278 SUPERFAMILY SSF111331 3 267 2.22E-72 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L12_04695 e8b4b7ad663faa4c2d5f45b240d79c21 278 Pfam PF01513 ATP-NAD kinase 2 261 1.3E-68 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L12_04695 e8b4b7ad663faa4c2d5f45b240d79c21 278 Gene3D G3DSA:3.40.50.10330 20 267 3.6E-71 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L12_05940 4efed6ec6776fe060fda203d9667eede 421 Pfam PF13263 PHP-associated 175 225 2.8E-5 T 23-10-2018 A3L12_05940 4efed6ec6776fe060fda203d9667eede 421 Gene3D G3DSA:3.20.20.140 2 230 1.1E-15 T 23-10-2018 A3L12_05940 4efed6ec6776fe060fda203d9667eede 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 381 3.9E-124 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A3L12_05940 4efed6ec6776fe060fda203d9667eede 421 SUPERFAMILY SSF89550 5 227 1.14E-14 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L12_05535 1222beef0fb60159adf12d7ad4f607cc 199 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 7 197 36.538 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A3L12_05535 1222beef0fb60159adf12d7ad4f607cc 199 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 46 58 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05535 1222beef0fb60159adf12d7ad4f607cc 199 Pfam PF01015 Ribosomal S3Ae family 10 197 1.1E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05535 1222beef0fb60159adf12d7ad4f607cc 199 SMART SM01397 7 197 5.7E-100 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 Gene3D G3DSA:3.40.50.10800 171 255 1.4E-119 T 23-10-2018 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 Hamap MF_00568 Quinolinate synthase A [nadA]. 2 299 45.2 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 300 1.9E-114 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 Pfam PF02445 Quinolinate synthetase A protein 7 298 5.3E-109 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 SUPERFAMILY SSF142754 3 299 9.02E-113 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 Gene3D G3DSA:3.40.50.10800 6 280 1.4E-119 T 23-10-2018 A3L12_03040 b6e7ed85ed79e127b49bae0f003cee45 301 Gene3D G3DSA:3.40.50.10800 86 298 1.4E-119 T 23-10-2018 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 123 2.2E-18 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 1.1E-20 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 Gene3D G3DSA:1.10.10.10 3 66 1.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 SUPERFAMILY SSF47979 63 122 2.09E-17 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 Gene3D G3DSA:1.10.60.10 67 122 7.0E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 SMART SM00529 24 123 5.2E-40 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L12_04880 7b0cf23c5a1b2ac0a789e3e03054b79a 150 SUPERFAMILY SSF46785 3 62 4.49E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04360 f13b7139b77b63514c0e461cfa7a8f38 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 1.0E-31 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L12_04360 f13b7139b77b63514c0e461cfa7a8f38 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 6.0E-31 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L12_04360 f13b7139b77b63514c0e461cfa7a8f38 83 SUPERFAMILY SSF158436 3 83 4.97E-29 T 23-10-2018 A3L12_04360 f13b7139b77b63514c0e461cfa7a8f38 83 Gene3D G3DSA:1.20.1440.50 2 83 6.8E-30 T 23-10-2018 IPR023130 Ta0600-like superfamily A3L12_04360 f13b7139b77b63514c0e461cfa7a8f38 83 Hamap MF_00342 UPF0147 protein . 1 83 28.487 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L12_01940 9c4bf95d9da1a2e73d6c0cd11142a2d8 355 PIRSF PIRSF009433 1 354 1.1E-139 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L12_01940 9c4bf95d9da1a2e73d6c0cd11142a2d8 355 SUPERFAMILY SSF53067 1 302 3.74E-7 T 23-10-2018 A3L12_01940 9c4bf95d9da1a2e73d6c0cd11142a2d8 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 350 3.9E-127 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L12_04135 c6667eed7d96c696f7e592e74c904039 120 Pfam PF07892 Protein of unknown function (DUF1667) 37 118 6.8E-32 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A3L12_04135 c6667eed7d96c696f7e592e74c904039 120 Gene3D G3DSA:3.10.530.10 50 118 6.5E-23 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L12_04135 c6667eed7d96c696f7e592e74c904039 120 SUPERFAMILY SSF53706 5 52 1.3E-6 T 23-10-2018 A3L12_04135 c6667eed7d96c696f7e592e74c904039 120 Gene3D G3DSA:2.20.25.90 1 44 2.7E-5 T 23-10-2018 A3L12_04135 c6667eed7d96c696f7e592e74c904039 120 SUPERFAMILY SSF160148 49 119 3.53E-23 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 174 192 5.2E-46 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 230 250 5.2E-46 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 354 377 5.2E-46 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 47 67 5.2E-46 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 121 138 5.2E-46 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 Gene3D G3DSA:1.10.10.10 9 153 8.5E-51 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 Gene3D G3DSA:3.40.1360.10 154 383 1.8E-63 T 23-10-2018 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 SUPERFAMILY SSF56726 79 381 4.45E-78 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 256 272 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 224 245 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 105 116 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 127 144 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 145 160 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 200 217 5.4E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 Pfam PF04406 Type IIB DNA topoisomerase 81 149 5.1E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A3L12_07895 55b250bec77c71cd739b3835d9e6fe52 384 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 15 383 39.73 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 2.1E-177 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 Gene3D G3DSA:3.90.180.10 21 338 9.4E-134 T 23-10-2018 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 53.961 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 3.7E-27 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 SUPERFAMILY SSF50129 3 177 4.72E-54 T 23-10-2018 IPR011032 GroES-like superfamily A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 SUPERFAMILY SSF51735 146 310 5.6E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 Gene3D G3DSA:3.40.50.720 157 291 9.4E-134 T 23-10-2018 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 SMART SM00829 16 345 2.8E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A3L12_06060 9aa0248adc6206398cbccb3b29372a90 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 4.9E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L12_07920 f6ead5e289ee0aa6422aec636f00cde2 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 423 8.1E-99 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L12_07920 f6ead5e289ee0aa6422aec636f00cde2 427 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 341 361 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L12_07920 f6ead5e289ee0aa6422aec636f00cde2 427 Pfam PF00860 Permease family 17 393 3.2E-98 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 443 1.3E-53 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 PIRSF PIRSF000538 4 494 5.7E-176 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 Hamap MF_00186 Glycerol kinase [glpK]. 4 490 56.519 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 489 9.8E-211 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 SUPERFAMILY SSF53067 6 250 1.02E-91 T 23-10-2018 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 Gene3D G3DSA:3.30.420.40 3 249 1.9E-110 T 23-10-2018 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 Gene3D G3DSA:3.30.420.40 250 497 2.7E-92 T 23-10-2018 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 357 377 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 248 4.0E-82 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A3L12_04120 4f6264d37064001c0533fd19d92d2652 501 SUPERFAMILY SSF53067 251 489 5.18E-82 T 23-10-2018 A3L12_06250 874ada3e1f21ac5b98083a56568160c6 129 Pfam PF04475 Protein of unknown function (DUF555) 3 104 1.6E-39 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L12_06250 874ada3e1f21ac5b98083a56568160c6 129 PIRSF PIRSF016934 1 123 5.5E-53 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L12_06250 874ada3e1f21ac5b98083a56568160c6 129 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 7.0E-50 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L12_06250 874ada3e1f21ac5b98083a56568160c6 129 Hamap MF_01223 UPF0212 protein . 1 112 32.256 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 Pfam PF00128 Alpha amylase, catalytic domain 329 634 7.8E-61 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 77 126 1.7E-10 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 SUPERFAMILY SSF51011 675 739 5.33E-5 T 23-10-2018 A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 Pfam PF11941 Domain of unknown function (DUF3459) 657 738 2.0E-7 T 23-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 Gene3D G3DSA:2.60.40.10 61 160 8.7E-19 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 SUPERFAMILY SSF81296 69 158 2.01E-15 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 SUPERFAMILY SSF51445 228 671 2.18E-103 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 SMART SM00642 275 664 3.3E-99 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L12_05090 803b5ea75c54f5fbc4a21ad8db5d6b46 742 Gene3D G3DSA:3.20.20.80 261 666 4.6E-118 T 23-10-2018 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Gene3D G3DSA:3.30.230.10 352 562 4.1E-71 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 SUPERFAMILY SSF54211 352 513 9.1E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Gene3D G3DSA:3.30.565.10 1 231 1.1E-65 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 531 7.1E-224 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 549 31.316 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 138 6.5E-12 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Gene3D G3DSA:1.10.8.50 232 307 8.2E-7 T 23-10-2018 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 352 549 4.0E-95 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 PIRSF PIRSF006553 1 563 1.3E-207 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 SMART SM00387 31 151 2.5E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 SUPERFAMILY SSF55874 18 228 2.75E-26 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L12_07900 27b3089558e975cb2e2912f9d33ec8ad 563 Pfam PF09239 Topoisomerase VI B subunit, transducer 353 508 1.1E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L12_07220 ba0de635f352a1b96eb3cc35abdbc128 116 Pfam PF02001 Protein of unknown function DUF134 13 108 4.7E-27 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L12_07220 ba0de635f352a1b96eb3cc35abdbc128 116 Gene3D G3DSA:1.10.10.10 47 96 6.1E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07220 ba0de635f352a1b96eb3cc35abdbc128 116 Hamap MF_00674 UPF0251 protein . 14 111 24.108 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L12_07220 ba0de635f352a1b96eb3cc35abdbc128 116 SUPERFAMILY SSF88659 48 95 3.92E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L12_04535 52d845f09d8d111dee49e78698fcc86e 161 SUPERFAMILY SSF143437 40 149 9.42E-16 T 23-10-2018 A3L12_04535 52d845f09d8d111dee49e78698fcc86e 161 Gene3D G3DSA:3.30.2130.30 11 152 1.4E-12 T 23-10-2018 A3L12_04535 52d845f09d8d111dee49e78698fcc86e 161 Pfam PF02926 THUMP domain 29 149 1.3E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_04535 52d845f09d8d111dee49e78698fcc86e 161 SMART SM00981 63 150 3.1E-15 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_00050 96ed39afcb24a21b836711dba866a86b 200 SUPERFAMILY SSF109755 1 198 2.51E-29 T 23-10-2018 A3L12_00050 96ed39afcb24a21b836711dba866a86b 200 Pfam PF01895 PhoU domain 117 188 1.3E-11 T 23-10-2018 IPR026022 PhoU domain A3L12_00050 96ed39afcb24a21b836711dba866a86b 200 Pfam PF01895 PhoU domain 9 96 1.7E-6 T 23-10-2018 IPR026022 PhoU domain A3L12_00050 96ed39afcb24a21b836711dba866a86b 200 Gene3D G3DSA:1.20.58.220 1 200 1.4E-28 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_04025 140e013dff133ce3980e73fdf941997f 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 266 369 8.2E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L12_04025 140e013dff133ce3980e73fdf941997f 396 SUPERFAMILY SSF52518 8 254 5.59E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_04025 140e013dff133ce3980e73fdf941997f 396 Gene3D G3DSA:3.40.50.970 7 255 4.7E-97 T 23-10-2018 A3L12_04025 140e013dff133ce3980e73fdf941997f 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 242 1.4E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_04025 140e013dff133ce3980e73fdf941997f 396 SUPERFAMILY SSF52922 257 377 1.31E-35 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_04025 140e013dff133ce3980e73fdf941997f 396 Gene3D G3DSA:3.40.50.920 256 396 9.1E-44 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 Gene3D G3DSA:1.20.1090.10 156 345 7.8E-67 T 23-10-2018 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 Gene3D G3DSA:3.40.50.1970 1 155 5.0E-33 T 23-10-2018 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 346 47.029 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 SUPERFAMILY SSF56796 3 339 4.58E-72 T 23-10-2018 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 PIRSF PIRSF000112 1 343 1.5E-67 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L12_06780 498e580299cb5b375cc270481a0f53c0 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 18 268 9.8E-73 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 Gene3D G3DSA:3.40.50.620 1 305 7.3E-148 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.759 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 Pfam PF09190 DALR domain 356 415 2.1E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 SUPERFAMILY SSF52374 4 314 8.7E-111 T 23-10-2018 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 SMART SM00840 356 417 9.7E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 1.6E-136 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 SUPERFAMILY SSF47323 316 473 3.05E-33 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 473 1.1E-178 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L12_05235 a503d9ffec12f78980ce9628c18b3942 476 Gene3D G3DSA:1.20.120.640 306 473 2.0E-36 T 23-10-2018 A3L12_02495 97c3c266a0dca20a0db6a37c37e25ff5 305 Pfam PF04055 Radical SAM superfamily 102 209 9.7E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_02495 97c3c266a0dca20a0db6a37c37e25ff5 305 Gene3D G3DSA:3.20.20.70 49 269 3.1E-29 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_02495 97c3c266a0dca20a0db6a37c37e25ff5 305 SUPERFAMILY SSF102114 54 260 4.45E-31 T 23-10-2018 A3L12_02495 97c3c266a0dca20a0db6a37c37e25ff5 305 SMART SM00729 55 252 1.9E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_07970 5100d680155e54f8bca15c62ce70cf8b 223 Pfam PF08241 Methyltransferase domain 44 132 2.3E-26 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L12_07970 5100d680155e54f8bca15c62ce70cf8b 223 SUPERFAMILY SSF53335 2 210 1.02E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07970 5100d680155e54f8bca15c62ce70cf8b 223 Gene3D G3DSA:3.40.50.150 1 190 2.8E-54 T 23-10-2018 A3L12_07475 f6bda038102bb7690347c02e143fa91c 239 SUPERFAMILY SSF52540 2 222 4.49E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07475 f6bda038102bb7690347c02e143fa91c 239 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_07475 f6bda038102bb7690347c02e143fa91c 239 Gene3D G3DSA:3.40.50.300 1 228 8.2E-52 T 23-10-2018 A3L12_07475 f6bda038102bb7690347c02e143fa91c 239 Pfam PF00005 ABC transporter 18 160 6.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07475 f6bda038102bb7690347c02e143fa91c 239 SMART SM00382 26 214 1.0E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 212 3.0E-7 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 SUPERFAMILY SSF51735 3 140 1.43E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 Gene3D G3DSA:3.40.50.720 3 308 2.9E-85 T 23-10-2018 A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 SUPERFAMILY SSF55347 126 305 4.58E-23 T 23-10-2018 A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 Gene3D G3DSA:3.30.360.10 122 321 2.9E-85 T 23-10-2018 A3L12_01515 f2b91e40fb7a04c6ea0d8af2a6188d1d 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 1.6E-28 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 SUPERFAMILY SSF54843 8 153 1.1E-45 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 3.3E-65 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.607 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 1.0E-33 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A3L12_00615 fe78b91aca673636774cb9f7799165a2 156 Gene3D G3DSA:3.90.470.10 6 156 1.6E-50 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 PIRSF PIRSF006293 1 237 6.6E-69 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 3.7E-49 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 SUPERFAMILY SSF52402 1 234 6.17E-52 T 23-10-2018 A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 2.1E-62 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 Gene3D G3DSA:3.40.50.620 1 235 9.4E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_01365 810f9b74fe7dc34e49184dd002166c5b 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 44.426 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L12_02655 00799fcd7e6a75651b040eb1e0f69ffd 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 3.8E-50 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L12_02655 00799fcd7e6a75651b040eb1e0f69ffd 340 SUPERFAMILY SSF159071 255 339 1.57E-17 T 23-10-2018 A3L12_02655 00799fcd7e6a75651b040eb1e0f69ffd 340 Gene3D G3DSA:1.10.10.10 1 101 1.3E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_02655 00799fcd7e6a75651b040eb1e0f69ffd 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 5.9E-25 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_02655 00799fcd7e6a75651b040eb1e0f69ffd 340 SUPERFAMILY SSF46785 1 94 2.65E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01540 fe478a60f52c25f6046f9a317418de62 304 Pfam PF05763 Protein of unknown function (DUF835) 166 258 2.9E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 1.0E-85 T 23-10-2018 IPR011903 Glutaredoxin-like domain A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 SUPERFAMILY SSF52833 121 221 1.09E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 Pfam PF13192 Thioredoxin domain 137 222 1.8E-14 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 Gene3D G3DSA:3.40.30.10 120 225 7.7E-26 T 23-10-2018 A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 Gene3D G3DSA:3.40.30.10 1 117 3.4E-34 T 23-10-2018 A3L12_01955 dece054d13160910b7dfd458f6f3323e 226 SUPERFAMILY SSF52833 5 116 1.87E-23 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 Gene3D G3DSA:3.50.20.10 44 156 4.3E-34 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 5.0E-67 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 SUPERFAMILY SSF56271 2 155 1.44E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 1.3E-39 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 Gene3D G3DSA:3.30.60.30 1 43 6.6E-18 T 23-10-2018 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 47.997 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 PIRSF PIRSF005216 2 157 1.2E-46 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_02175 b78a11f8f9ed9a2cce56caa1414c45ed 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 2.0E-39 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L12_04530 89ced0fdcc34aa6a6a56f9d521e50c9a 164 Pfam PF02915 Rubrerythrin 18 156 2.0E-19 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_04530 89ced0fdcc34aa6a6a56f9d521e50c9a 164 Gene3D G3DSA:1.20.1260.10 8 159 8.5E-33 T 23-10-2018 IPR012347 Ferritin-like A3L12_04530 89ced0fdcc34aa6a6a56f9d521e50c9a 164 SUPERFAMILY SSF47240 16 161 1.55E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_04590 3c523ac693fa1016550cedb438cc2214 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 1.3E-59 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L12_04590 3c523ac693fa1016550cedb438cc2214 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 41.156 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A3L12_04590 3c523ac693fa1016550cedb438cc2214 184 Gene3D G3DSA:3.90.950.10 1 184 1.5E-71 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L12_04590 3c523ac693fa1016550cedb438cc2214 184 Pfam PF01725 Ham1 family 3 178 9.0E-50 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L12_04590 3c523ac693fa1016550cedb438cc2214 184 SUPERFAMILY SSF52972 1 182 1.78E-61 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 SUPERFAMILY SSF75217 1 172 9.68E-70 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 Gene3D G3DSA:3.40.1280.10 1 175 2.6E-80 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 PIRSF PIRSF016123 1 175 6.1E-85 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 175 2.0E-43 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 174 44.131 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L12_03570 a7d222475048fa97fb7dc1c800074da6 175 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 171 1.4E-49 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Pfam PF08264 Anticodon-binding domain of tRNA 723 855 3.9E-32 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 7 964 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Gene3D G3DSA:3.90.740.10 204 450 1.1E-301 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 SUPERFAMILY SSF47323 712 908 3.92E-42 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 SUPERFAMILY SSF52374 3 692 2.29E-102 T 23-10-2018 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 SUPERFAMILY SSF50677 209 442 8.16E-35 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Gene3D G3DSA:1.10.10.720 863 914 5.6E-49 T 23-10-2018 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 11 687 1.4E-68 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Gene3D G3DSA:3.30.2320.20 832 964 5.6E-49 T 23-10-2018 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Gene3D G3DSA:3.40.50.620 8 686 1.1E-301 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 5 964 18.381 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00965 cd48b8b70d04b4c37856f9fae458b76f 964 Gene3D G3DSA:1.10.730.10 688 807 8.6E-34 T 23-10-2018 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 178 195 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 Gene3D G3DSA:3.40.190.10 183 417 2.2E-139 T 23-10-2018 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 Pfam PF13416 Bacterial extracellular solute-binding protein 91 386 7.5E-53 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 Gene3D G3DSA:3.40.190.10 76 402 2.2E-139 T 23-10-2018 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 SUPERFAMILY SSF53850 70 441 8.03E-94 T 23-10-2018 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 PRINTS PR00181 Maltose binding protein signature 196 215 2.7E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 PRINTS PR00181 Maltose binding protein signature 175 194 2.7E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 PRINTS PR00181 Maltose binding protein signature 402 421 2.7E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 PRINTS PR00181 Maltose binding protein signature 273 292 2.7E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L12_02645 7d1279f22185ac310174924b8268fb1e 447 PRINTS PR00181 Maltose binding protein signature 113 131 2.7E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Gene3D G3DSA:3.90.1020.10 356 425 1.3E-23 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Gene3D G3DSA:3.20.20.105 1 355 8.5E-122 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Pfam PF01472 PUA domain 505 576 1.2E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 356 425 4.7E-38 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 SUPERFAMILY SSF51713 3 353 3.27E-115 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 SUPERFAMILY SSF88697 503 577 4.75E-21 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 503 576 1.1E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Pfam PF01702 Queuine tRNA-ribosyltransferase 108 329 5.5E-41 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 SUPERFAMILY SSF88802 356 501 1.77E-41 T 23-10-2018 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 SMART SM00359 504 578 2.3E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 336 6.4E-87 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Gene3D G3DSA:2.30.130.10 501 578 5.1E-32 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 5 386 1.6E-168 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 434 502 7.7E-24 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 5 530 48.295 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_05185 573f45db40211aebb8e47eb301345e1e 579 Gene3D G3DSA:3.10.450.90 428 500 1.8E-28 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PIRSF PIRSF001529 1 446 7.1E-152 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 SUPERFAMILY SSF46589 2 115 1.99E-24 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 Gene3D G3DSA:3.30.930.10 108 455 4.7E-134 T 23-10-2018 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 Gene3D G3DSA:1.10.287.40 1 107 9.0E-31 T 23-10-2018 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.6E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.6E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.6E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.6E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.6E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 SUPERFAMILY SSF55681 154 445 4.75E-88 T 23-10-2018 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 438 1.9E-158 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 8.8E-25 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 420 1.6E-36 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06605 e6df817cd2339675c12687dd3680b2af 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.363 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L12_02840 1221184ca3ff6f6742ebd49e71d7bd90 303 SUPERFAMILY SSF53448 8 252 4.46E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02840 1221184ca3ff6f6742ebd49e71d7bd90 303 TIGRFAM TIGR04182 glyco_TIGR04182: glycosyltransferase, TIGR04182 family 8 294 2.2E-117 T 23-10-2018 IPR026456 Glycosyltransferase AglJ GO:0016757 A3L12_02840 1221184ca3ff6f6742ebd49e71d7bd90 303 Gene3D G3DSA:3.90.550.10 2 232 4.1E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02840 1221184ca3ff6f6742ebd49e71d7bd90 303 Pfam PF00535 Glycosyl transferase family 2 10 164 2.4E-21 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_06240 f6cf2917318f69e6b531d4168387dc51 131 Pfam PF01201 Ribosomal protein S8e 3 125 2.5E-32 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A3L12_06240 f6cf2917318f69e6b531d4168387dc51 131 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 31.589 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_06240 f6cf2917318f69e6b531d4168387dc51 131 Gene3D G3DSA:2.40.10.310 60 131 9.3E-30 T 23-10-2018 A3L12_06240 f6cf2917318f69e6b531d4168387dc51 131 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 1.8E-45 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06240 f6cf2917318f69e6b531d4168387dc51 131 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00920 417bc4b8f35fb34bcb96c66b2f004377 294 Gene3D G3DSA:3.40.830.10 3 293 1.3E-66 T 23-10-2018 A3L12_00920 417bc4b8f35fb34bcb96c66b2f004377 294 Hamap MF_00055 MEMO1 family protein . 3 292 58.024 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L12_00920 417bc4b8f35fb34bcb96c66b2f004377 294 Pfam PF01875 Memo-like protein 7 290 2.4E-71 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L12_00920 417bc4b8f35fb34bcb96c66b2f004377 294 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 290 4.4E-88 T 23-10-2018 A3L12_01315 3123048ee5be8979416a91ee329004a3 313 Pfam PF00005 ABC transporter 20 156 1.3E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01315 3123048ee5be8979416a91ee329004a3 313 Gene3D G3DSA:3.40.50.300 2 220 9.5E-60 T 23-10-2018 A3L12_01315 3123048ee5be8979416a91ee329004a3 313 SMART SM00382 28 214 1.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01315 3123048ee5be8979416a91ee329004a3 313 SUPERFAMILY SSF52540 3 217 1.58E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00550 df91db79cb4192662dc45d2f3727ea84 281 SUPERFAMILY SSF51556 1 278 2.64E-33 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L12_00550 df91db79cb4192662dc45d2f3727ea84 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 278 8.0E-80 T 23-10-2018 A3L12_00550 df91db79cb4192662dc45d2f3727ea84 281 Gene3D G3DSA:3.20.20.140 3 279 2.9E-27 T 23-10-2018 A3L12_00550 df91db79cb4192662dc45d2f3727ea84 281 Pfam PF01026 TatD related DNase 5 275 2.4E-29 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L12_00550 df91db79cb4192662dc45d2f3727ea84 281 PIRSF PIRSF004961 1 280 5.8E-118 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 Gene3D G3DSA:3.100.10.20 1 82 6.8E-30 T 23-10-2018 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 311 24.847 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 325 8.4E-133 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 Gene3D G3DSA:1.20.120.920 83 326 1.6E-64 T 23-10-2018 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 321 8.5E-95 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L12_06405 42b25d453882025cdee860c9a4ef811c 326 Pfam PF01867 CRISPR associated protein Cas1 8 280 3.6E-83 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A3L12_01650 7332480ad3b501652c460f8666dbe233 226 SUPERFAMILY SSF56300 17 146 6.65E-15 T 23-10-2018 A3L12_01650 7332480ad3b501652c460f8666dbe233 226 PIRSF PIRSF000887 2 224 3.9E-61 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L12_01650 7332480ad3b501652c460f8666dbe233 226 Pfam PF00149 Calcineurin-like phosphoesterase 16 115 3.6E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_01650 7332480ad3b501652c460f8666dbe233 226 Gene3D G3DSA:3.60.21.10 16 161 1.3E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_01650 7332480ad3b501652c460f8666dbe233 226 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 6 221 6.2E-49 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A3L12_05880 c30a58a533392d8a311c792086420524 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.365 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A3L12_05880 c30a58a533392d8a311c792086420524 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 308 5.7E-66 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 Gene3D G3DSA:3.40.50.1370 10 307 1.5E-137 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.8E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 SUPERFAMILY SSF53671 4 313 1.1E-115 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.1E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.1E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 2.1E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.1E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 2.1E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.6E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.6E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.6E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.6E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 Gene3D G3DSA:3.40.50.1370 138 297 1.5E-137 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_05880 c30a58a533392d8a311c792086420524 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 1.1E-144 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 Gene3D G3DSA:3.30.1020.10 145 216 1.8E-34 T 23-10-2018 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 Hamap MF_00401 Peroxiredoxin. 2 215 50.802 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 PIRSF PIRSF000239 1 215 6.0E-67 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 Pfam PF00578 AhpC/TSA family 4 134 4.9E-31 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 Gene3D G3DSA:3.40.30.10 1 144 1.5E-43 T 23-10-2018 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 1.3E-7 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L12_07610 6a7defcec7ed0bc9b6d7082afd51ff29 216 SUPERFAMILY SSF52833 1 215 4.71E-62 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 SMART SM01384 2 191 1.5E-134 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 42.736 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 Pfam PF00827 Ribosomal L15 2 189 2.4E-89 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 Gene3D G3DSA:3.40.1120.10 1 193 1.4E-89 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00975 5dd11d5828d67b3c899c00ae8efae4df 194 SUPERFAMILY SSF54189 1 192 1.2E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07300 16c301e90bb88b79da855dc913d9b740 308 Gene3D G3DSA:3.90.25.10 168 301 4.9E-106 T 23-10-2018 A3L12_07300 16c301e90bb88b79da855dc913d9b740 308 SUPERFAMILY SSF51735 1 304 1.96E-101 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_07300 16c301e90bb88b79da855dc913d9b740 308 Gene3D G3DSA:3.40.50.720 8 289 4.9E-106 T 23-10-2018 A3L12_07300 16c301e90bb88b79da855dc913d9b740 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 2.8E-61 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Gene3D G3DSA:3.30.420.360 383 755 3.1E-107 T 23-10-2018 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 SUPERFAMILY SSF55821 175 390 5.8E-46 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 SUPERFAMILY SSF53067 422 754 2.07E-5 T 23-10-2018 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Pfam PF07503 HypF finger 158 191 8.3E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Pfam PF07503 HypF finger 108 141 1.4E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Pfam PF00708 Acylphosphatase 4 87 1.5E-22 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Gene3D G3DSA:3.90.870.50 6 362 3.3E-142 T 23-10-2018 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Pfam PF01300 Telomere recombination 208 383 3.5E-46 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 PIRSF PIRSF006256 1 765 3.4E-283 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 SUPERFAMILY SSF54975 1 88 1.05E-25 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Gene3D G3DSA:3.30.110.120 252 371 3.3E-142 T 23-10-2018 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 Gene3D G3DSA:3.30.420.350 486 743 3.1E-107 T 23-10-2018 A3L12_01890 7e3299c4aaea82810eb2aa3045a6333e 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 755 3.3E-263 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L12_02715 029cd93aa36dd767fab2e3819fdc568e 73 Gene3D G3DSA:3.10.20.30 1 73 1.2E-15 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_02715 029cd93aa36dd767fab2e3819fdc568e 73 Pfam PF02597 ThiS family 5 73 3.4E-13 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L12_02715 029cd93aa36dd767fab2e3819fdc568e 73 SUPERFAMILY SSF54285 15 73 1.05E-11 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L12_06025 869e36cd76d18506e2f373fc60396117 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.021 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A3L12_06025 869e36cd76d18506e2f373fc60396117 98 Gene3D G3DSA:2.30.30.70 2 97 1.2E-35 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06025 869e36cd76d18506e2f373fc60396117 98 SUPERFAMILY SSF50104 6 97 9.02E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_06025 869e36cd76d18506e2f373fc60396117 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06025 869e36cd76d18506e2f373fc60396117 98 Pfam PF01157 Ribosomal protein L21e 6 96 1.4E-31 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 Pfam PF00347 Ribosomal protein L6 13 85 2.4E-18 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 Pfam PF00347 Ribosomal protein L6 97 171 1.5E-15 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 PIRSF PIRSF002162 5 182 9.7E-40 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 1.1E-78 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 SUPERFAMILY SSF56053 8 85 2.76E-22 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.26 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 Gene3D G3DSA:3.90.930.12 6 85 1.3E-30 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 Gene3D G3DSA:3.90.930.12 86 182 2.1E-37 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00675 a8de35e9cd3ab07612ccab23e464aee5 184 SUPERFAMILY SSF56053 86 177 1.99E-29 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 Gene3D G3DSA:3.30.1430.10 77 188 6.1E-121 T 23-10-2018 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 Pfam PF00297 Ribosomal protein L3 3 347 1.6E-89 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.197 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 Gene3D G3DSA:4.10.960.10 6 257 6.1E-121 T 23-10-2018 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 SUPERFAMILY SSF50447 3 347 7.24E-95 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 2.5E-133 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00590 0759c3a5241cab4e1823b9081896d214 347 Gene3D G3DSA:2.40.30.10 39 327 6.1E-121 T 23-10-2018 A3L12_07065 7975fec9bd6e7dc37f47162088a9a1d3 204 PIRSF PIRSF015877 1 199 1.9E-64 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 8.4E-28 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 SUPERFAMILY SSF54999 3 100 1.96E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 SMART SM01403 5 99 2.9E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 1.9E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 Gene3D G3DSA:3.30.70.600 1 101 1.9E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07860 aca8ba92c3d1893b70433adee83a204d 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.731 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06820 16c2b972b7544af05da0e9eadf4eee68 361 SUPERFAMILY SSF54001 134 194 2.35E-6 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L12_06820 16c2b972b7544af05da0e9eadf4eee68 361 Pfam PF04473 Transglutaminase-like domain 77 224 2.4E-38 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L12_06820 16c2b972b7544af05da0e9eadf4eee68 361 Gene3D G3DSA:3.10.620.30 86 225 1.2E-5 T 23-10-2018 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 PRINTS PR00112 Acylphosphatase signature 5 20 9.3E-11 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 PRINTS PR00112 Acylphosphatase signature 26 51 9.3E-11 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 Gene3D G3DSA:3.30.70.100 1 91 1.2E-36 T 23-10-2018 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 Pfam PF00708 Acylphosphatase 6 88 4.9E-27 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 SUPERFAMILY SSF54975 2 90 4.14E-31 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_04085 47085153c98828bead4e5af31edaa5fc 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L12_00360 cf10f9cfc4f89e26fa6ce1dbc4922284 487 Pfam PF05124 S-layer like family, C-terminal region 399 485 9.4E-8 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L12_01960 6826ac40f7ae24f8cf68607dda851046 241 SMART SM00418 5 86 2.1E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_01960 6826ac40f7ae24f8cf68607dda851046 241 SUPERFAMILY SSF46785 3 94 1.25E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01960 6826ac40f7ae24f8cf68607dda851046 241 Gene3D G3DSA:1.10.10.10 2 77 1.1E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01960 6826ac40f7ae24f8cf68607dda851046 241 Gene3D G3DSA:1.10.10.10 165 233 3.8E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01960 6826ac40f7ae24f8cf68607dda851046 241 Pfam PF12840 Helix-turn-helix domain 5 59 5.5E-8 T 23-10-2018 A3L12_03470 c1aa1685ad3d298dc7f015d215e2774c 352 Gene3D G3DSA:3.40.50.300 16 216 4.9E-28 T 23-10-2018 A3L12_03470 c1aa1685ad3d298dc7f015d215e2774c 352 SUPERFAMILY SSF52540 6 169 3.99E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03470 c1aa1685ad3d298dc7f015d215e2774c 352 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 210 2.7E-38 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A3L12_03740 f87a49079dfbc5b3ea08dcdfc8e25cbc 211 Gene3D G3DSA:3.60.15.10 1 201 2.8E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_03740 f87a49079dfbc5b3ea08dcdfc8e25cbc 211 SUPERFAMILY SSF56281 1 197 1.97E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_03740 f87a49079dfbc5b3ea08dcdfc8e25cbc 211 SMART SM00849 7 175 2.4E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_03740 f87a49079dfbc5b3ea08dcdfc8e25cbc 211 Pfam PF13483 Beta-lactamase superfamily domain 3 175 9.6E-29 T 23-10-2018 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 14 148 33.134 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 15 147 1.3E-50 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 SUPERFAMILY SSF100966 14 115 3.14E-26 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 SMART SM00653 35 142 2.6E-56 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 Gene3D G3DSA:3.30.70.3150 46 136 5.3E-31 T 23-10-2018 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 Pfam PF01873 Domain found in IF2B/IF5 30 141 3.1E-35 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L12_00515 e44ca6899b03e9a4cba66ee9e2d752c9 148 SUPERFAMILY SSF75689 112 147 6.41E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L12_05570 90f992904b83340ce5d563ff71f271b1 130 PIRSF PIRSF004966 1 130 2.2E-53 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A3L12_05570 90f992904b83340ce5d563ff71f271b1 130 Hamap MF_00078 UPF0107 protein . 2 129 33.132 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A3L12_05570 90f992904b83340ce5d563ff71f271b1 130 Pfam PF01989 Protein of unknown function DUF126 24 102 4.9E-35 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A3L12_05570 90f992904b83340ce5d563ff71f271b1 130 SUPERFAMILY SSF52016 1 127 5.89E-44 T 23-10-2018 A3L12_05570 90f992904b83340ce5d563ff71f271b1 130 Gene3D G3DSA:3.50.30.10 1 130 3.9E-49 T 23-10-2018 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 SMART SM01400 2 110 9.2E-29 T 23-10-2018 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 Pfam PF00156 Phosphoribosyl transferase domain 141 239 2.5E-16 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 18 109 6.9E-19 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 16 277 1.8E-84 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 35.62 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 SUPERFAMILY SSF53271 62 268 1.13E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 Gene3D G3DSA:3.40.50.2020 139 263 1.3E-77 T 23-10-2018 A3L12_03730 17c5b74187fdb4835f76a1e63ee9b4ce 283 Gene3D G3DSA:3.40.50.2020 18 138 1.3E-77 T 23-10-2018 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Gene3D G3DSA:2.40.340.10 320 396 4.2E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 SMART SM00852 186 317 8.4E-28 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Gene3D G3DSA:3.40.980.10 20 314 9.0E-108 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Gene3D G3DSA:2.170.190.11 50 148 9.0E-108 T 23-10-2018 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 SUPERFAMILY SSF63867 327 396 8.63E-20 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 4.0E-45 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 SUPERFAMILY SSF53218 181 322 1.7E-34 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Pfam PF03454 MoeA C-terminal region (domain IV) 330 395 3.6E-17 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Gene3D G3DSA:3.90.105.10 27 181 9.0E-108 T 23-10-2018 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 SUPERFAMILY SSF63882 7 182 8.11E-56 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_04850 6249c525e5eac7fe800660bfbd64240f 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 1.3E-16 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Pfam PF09334 tRNA synthetases class I (M) 4 408 3.2E-158 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 SUPERFAMILY SSF50249 632 732 3.67E-39 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 SUPERFAMILY SSF57770 139 173 2.62E-11 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Pfam PF01588 Putative tRNA binding domain 639 731 1.5E-34 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Gene3D G3DSA:3.40.50.620 5 316 2.5E-143 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 8.4E-175 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Gene3D G3DSA:1.10.730.10 398 548 8.1E-97 T 23-10-2018 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 SUPERFAMILY SSF47323 398 647 1.2E-44 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.3E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Gene3D G3DSA:2.170.220.10 98 252 2.5E-143 T 23-10-2018 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 613 733 1.7E-41 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.508 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Pfam PF08264 Anticodon-binding domain of tRNA 434 523 1.6E-11 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 SUPERFAMILY SSF52374 3 395 2.84E-106 T 23-10-2018 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Gene3D G3DSA:1.10.730.10 341 579 8.1E-97 T 23-10-2018 A3L12_05355 85ebfc15fbe7a6f63bc15704007919bd 733 Gene3D G3DSA:2.40.50.140 627 733 9.1E-46 T 23-10-2018 A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 Gene3D G3DSA:3.40.50.1820 375 630 7.1E-73 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 Gene3D G3DSA:2.120.10.60 20 141 5.6E-15 T 23-10-2018 A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 Gene3D G3DSA:2.120.10.30 142 371 5.3E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 SUPERFAMILY SSF82171 20 367 9.55E-31 T 23-10-2018 A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 Pfam PF07676 WD40-like Beta Propeller Repeat 54 89 2.5E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 Pfam PF00326 Prolyl oligopeptidase family 419 630 4.2E-58 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L12_07015 68f540f68daa5dfe5c487ddbbf5819c8 631 SUPERFAMILY SSF53474 373 629 5.16E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 Gene3D G3DSA:3.40.640.10 55 291 4.3E-140 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 Pfam PF00155 Aminotransferase class I and II 39 383 1.3E-71 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 SUPERFAMILY SSF53383 4 391 1.77E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 Gene3D G3DSA:3.90.1150.10 35 385 4.3E-140 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_03780 f6d77d801ad7ba69bbc8c05a4130b9dd 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 4.9E-201 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 5.9E-37 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Gene3D G3DSA:3.30.70.2200 2 155 2.7E-58 T 23-10-2018 A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 425 36.057 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Gene3D G3DSA:3.90.600.20 156 251 1.5E-33 T 23-10-2018 A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Gene3D G3DSA:2.40.50.1010 252 401 6.3E-43 T 23-10-2018 A3L12_07690 187f1535be31a14d29aa864005d745eb 435 Pfam PF01336 OB-fold nucleic acid binding domain 269 341 3.6E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 SUPERFAMILY SSF53790 1 259 2.88E-60 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.5E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 35.096 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 Gene3D G3DSA:3.40.1010.10 1 114 2.9E-38 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 PIRSF PIRSF036432 2 260 1.2E-94 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 Gene3D G3DSA:3.30.950.10 115 264 2.2E-52 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A3L12_02145 68d811a08ff2641925ff44aa8e04a22a 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 3.0E-97 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L12_08115 8d41fab7ca7aed6cc3efe290e627ed77 141 Gene3D G3DSA:3.90.220.20 2 119 2.4E-26 T 23-10-2018 A3L12_08115 8d41fab7ca7aed6cc3efe290e627ed77 141 Gene3D G3DSA:3.90.220.20 120 138 2.4E-26 T 23-10-2018 A3L12_08115 8d41fab7ca7aed6cc3efe290e627ed77 141 SUPERFAMILY SSF116734 5 141 2.62E-25 T 23-10-2018 A3L12_08115 8d41fab7ca7aed6cc3efe290e627ed77 141 Pfam PF01420 Type I restriction modification DNA specificity domain 11 114 6.8E-12 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 314 8.6E-143 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 Pfam PF00696 Amino acid kinase family 2 296 6.3E-30 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PIRSF PIRSF000723 1 314 1.9E-138 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 3.8E-66 T 23-10-2018 A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 Gene3D G3DSA:3.40.1160.10 1 315 1.7E-134 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_04150 8c5e382e8241f0d0d9bc2ed2d8f8adfa 315 SUPERFAMILY SSF53633 1 313 2.49E-86 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_00160 522149641cd7be3d78be0e22721c149f 497 Gene3D G3DSA:1.10.1370.30 1 497 3.9E-196 T 23-10-2018 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 496 2.4E-103 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 SUPERFAMILY SSF55486 7 497 8.43E-112 T 23-10-2018 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PIRSF PIRSF006615 5 497 2.0E-197 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 295 311 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 448 466 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 231 247 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 404 425 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 268 287 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 248 267 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 335 354 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 149 169 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_00160 522149641cd7be3d78be0e22721c149f 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 381 398 1.6E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L12_07990 8cced26123208563ff26650308a0859d 148 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 2.0E-21 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 SUPERFAMILY SSF47979 64 124 2.75E-16 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 3.3E-16 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 Gene3D G3DSA:1.10.10.10 3 67 2.0E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 5.7E-20 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 SUPERFAMILY SSF46785 3 63 2.61E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 Gene3D G3DSA:1.10.60.10 68 125 5.9E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L12_00295 50c50d6ec23198bbd3f0dbaebcd0dee1 148 SMART SM00529 25 125 2.3E-42 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 338 8.1E-36 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Pfam PF02769 AIR synthase related protein, C-terminal domain 545 680 1.0E-20 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Pfam PF00586 AIR synthase related protein, N-terminal domain 68 172 3.1E-25 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Pfam PF00586 AIR synthase related protein, N-terminal domain 415 531 3.6E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 SUPERFAMILY SSF56042 540 694 1.12E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 709 259.595 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 3 702 1.3E-293 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Gene3D G3DSA:3.30.1330.10 27 176 1.5E-123 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Gene3D G3DSA:3.90.650.10 12 338 1.5E-123 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Gene3D G3DSA:3.30.1330.10 364 534 2.1E-57 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 SUPERFAMILY SSF55326 20 178 2.09E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 SUPERFAMILY SSF55326 374 532 2.22E-50 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 PIRSF PIRSF001587 1 709 1.2E-283 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 SUPERFAMILY SSF56042 184 400 6.13E-54 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03160 dabe3772db8e00e1e69a74c5788f6f4b 709 Gene3D G3DSA:3.90.650.10 537 706 1.2E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03610 3823597ce8331ad7c51941dd8872c444 424 Gene3D G3DSA:3.40.1710.10 42 202 4.6E-31 T 23-10-2018 A3L12_03610 3823597ce8331ad7c51941dd8872c444 424 Pfam PF12698 ABC-2 family transporter protein 21 403 3.7E-33 T 23-10-2018 A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 SMART SM00487 227 439 4.4E-14 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 SUPERFAMILY SSF52540 240 556 1.93E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 Pfam PF00270 DEAD/DEAH box helicase 235 410 6.6E-13 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 Pfam PF00271 Helicase conserved C-terminal domain 447 550 1.1E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 SMART SM00490 471 550 1.7E-10 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 207 1.2E-26 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 245 587 1.7E-97 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 Gene3D G3DSA:1.10.3210.30 1 143 5.4E-16 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 Gene3D G3DSA:3.40.50.300 226 420 4.5E-17 T 23-10-2018 A3L12_06395 5fdbdd286cd2a7b67f9ea76584593b8f 728 Gene3D G3DSA:3.40.50.300 428 623 7.0E-18 T 23-10-2018 A3L12_06310 b8e8d86ac8e6a09629f3aa66c3d6dd49 270 Gene3D G3DSA:3.90.1640.20 1 269 1.5E-96 T 23-10-2018 A3L12_06310 b8e8d86ac8e6a09629f3aa66c3d6dd49 270 Pfam PF14336 Domain of unknown function (DUF4392) 107 260 2.2E-47 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L12_06310 b8e8d86ac8e6a09629f3aa66c3d6dd49 270 Pfam PF14336 Domain of unknown function (DUF4392) 3 93 1.0E-14 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 SUPERFAMILY SSF50249 425 552 1.26E-39 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Gene3D G3DSA:3.30.470.30 221 422 2.4E-74 T 23-10-2018 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.781 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 1.0E-160 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Pfam PF04675 DNA ligase N terminus 3 176 1.4E-38 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 3.9E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 8.1E-65 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Gene3D G3DSA:2.40.50.140 423 559 2.0E-51 T 23-10-2018 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 SUPERFAMILY SSF56091 219 422 3.84E-55 T 23-10-2018 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 SUPERFAMILY SSF117018 1 242 6.15E-70 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L12_04250 ae47f803d1b9e1ee75faecf02fbd333b 559 Gene3D G3DSA:1.10.3260.10 1 220 5.1E-82 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 Gene3D G3DSA:3.40.640.10 81 349 1.8E-147 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 SUPERFAMILY SSF53383 3 445 8.23E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 PIRSF PIRSF006815 3 446 1.3E-154 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 Pfam PF02347 Glycine cleavage system P-protein 4 442 1.3E-118 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 Gene3D G3DSA:3.90.1150.10 70 442 1.8E-147 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_01665 049e369336021f4bbdebee46ba0a5a24 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 46.915 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 4.6E-153 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 Gene3D G3DSA:3.30.420.40 122 278 1.6E-113 T 23-10-2018 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.309 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 SUPERFAMILY SSF53067 1 293 3.67E-37 T 23-10-2018 A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 Pfam PF00814 Glycoprotease family 23 292 2.6E-94 T 23-10-2018 IPR000905 Gcp-like domain A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 2.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 3.5E-100 T 23-10-2018 IPR017861 Kae1/TsaD family A3L12_04700 427c9c83ecd20dfb15395ee96a87e334 325 Gene3D G3DSA:3.30.420.40 4 298 1.6E-113 T 23-10-2018 A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 Pfam PF09378 HAS barrel domain 11 112 3.2E-19 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 Pfam PF05872 Bacterial protein of unknown function (DUF853) 427 523 1.4E-4 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 Pfam PF01935 Domain of unknown function DUF87 152 378 1.8E-52 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 Gene3D G3DSA:3.40.50.300 326 546 2.2E-54 T 23-10-2018 A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 Gene3D G3DSA:3.40.50.300 138 257 1.0E-19 T 23-10-2018 A3L12_03805 c804ddc857b2a46dbd5537462011a0b7 583 SUPERFAMILY SSF52540 150 537 3.19E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.861 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 SUPERFAMILY SSF53649 4 406 5.02E-45 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 4.2E-52 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 Pfam PF01676 Metalloenzyme superfamily 5 400 7.7E-55 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 Gene3D G3DSA:3.30.70.2130 81 230 6.2E-141 T 23-10-2018 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 PIRSF PIRSF006392 1 407 2.8E-155 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 Gene3D G3DSA:3.40.720.10 7 397 6.2E-141 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_05860 77a166ef8ae6b984bb910256bd111631 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 2.7E-137 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 Gene3D G3DSA:3.30.70.20 52 132 1.2E-11 T 23-10-2018 A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 2.5E-23 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 SUPERFAMILY SSF52540 2 293 1.01E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 SUPERFAMILY SSF54862 56 120 4.95E-15 T 23-10-2018 A3L12_07280 4323e64968ab4e3bbfea95d282354369 295 Pfam PF00037 4Fe-4S binding domain 65 87 1.6E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_03745 a7c065279041072606b298faa7885895 225 PRINTS PR01874 DNA repair protein radA signature 189 215 4.0E-7 T 23-10-2018 A3L12_03745 a7c065279041072606b298faa7885895 225 PRINTS PR01874 DNA repair protein radA signature 11 39 4.0E-7 T 23-10-2018 A3L12_03745 a7c065279041072606b298faa7885895 225 SMART SM00382 19 178 0.0012 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03745 a7c065279041072606b298faa7885895 225 PIRSF PIRSF003336 1 219 9.6E-92 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L12_03745 a7c065279041072606b298faa7885895 225 Pfam PF08423 Rad51 2 164 2.9E-28 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L12_03745 a7c065279041072606b298faa7885895 225 SUPERFAMILY SSF52540 2 216 1.24E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03745 a7c065279041072606b298faa7885895 225 Gene3D G3DSA:3.40.50.300 7 218 1.6E-52 T 23-10-2018 A3L12_03745 a7c065279041072606b298faa7885895 225 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 216 6.0E-67 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L12_03745 a7c065279041072606b298faa7885895 225 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 216 35.534 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L12_02995 50cf15a40f6b6c2521ad43cd1b17f98f 358 Gene3D G3DSA:3.40.50.1100 48 349 5.1E-80 T 23-10-2018 A3L12_02995 50cf15a40f6b6c2521ad43cd1b17f98f 358 SUPERFAMILY SSF53686 2 357 5.5E-72 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L12_02995 50cf15a40f6b6c2521ad43cd1b17f98f 358 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 79 344 3.5E-57 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L12_02995 50cf15a40f6b6c2521ad43cd1b17f98f 358 Gene3D G3DSA:3.40.50.1100 93 186 5.1E-80 T 23-10-2018 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 PIRSF PIRSF500824 1 433 9.2E-212 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 41.976 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 PIRSF PIRSF001413 6 430 3.6E-155 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 SUPERFAMILY SSF53686 24 423 1.31E-109 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 2.5E-216 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 1.4E-43 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 Gene3D G3DSA:3.40.50.1100 11 236 5.8E-175 T 23-10-2018 A3L12_00990 d9413f8b0c3bf365ac05f89d384e3b52 441 Gene3D G3DSA:3.40.50.1100 10 417 5.8E-175 T 23-10-2018 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Gene3D G3DSA:2.40.50.100 113 184 8.4E-184 T 23-10-2018 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Gene3D G3DSA:2.40.30.20 1 69 7.8E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 SUPERFAMILY SSF52540 163 440 3.84E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 8.7E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.778 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Gene3D G3DSA:1.10.1140.10 435 585 1.4E-61 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 SUPERFAMILY SSF50615 1 68 1.41E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 SUPERFAMILY SSF47917 446 552 1.75E-27 T 23-10-2018 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Gene3D G3DSA:3.40.50.300 70 434 8.4E-184 T 23-10-2018 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 8.8E-48 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02470 dee49ecb9f046f8d4a8ebbdf414aef8b 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 1.4E-91 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 SUPERFAMILY SSF52490 36 239 6.93E-56 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 394 33.589 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 SUPERFAMILY SSF55307 238 352 3.89E-35 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 8.9E-41 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 SMART SM00864 37 236 1.1E-80 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 Pfam PF12327 FtsZ family, C-terminal domain 253 347 2.8E-24 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 SMART SM00865 238 355 3.6E-38 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 35 354 4.5E-110 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 PRINTS PR00423 Cell division protein FtsZ signature 122 142 1.1E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 PRINTS PR00423 Cell division protein FtsZ signature 158 179 1.1E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 PRINTS PR00423 Cell division protein FtsZ signature 220 242 1.1E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 PRINTS PR00423 Cell division protein FtsZ signature 243 264 1.1E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_02110 9536bbffa1115bb6e68dcc9adb6c9f27 410 Gene3D G3DSA:3.40.50.1440 35 347 3.2E-97 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 SUPERFAMILY SSF51735 12 262 4.05E-53 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.9E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 Gene3D G3DSA:3.40.50.720 4 265 2.4E-51 T 23-10-2018 A3L12_07700 9f4757635238ed674caaa84b0221ffc6 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 262 1.8E-34 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:3.30.420.10 131 347 4.9E-165 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:3.30.342.10 3 366 4.9E-165 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 ProSitePatterns PS00116 DNA polymerase family B signature. 897 905 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Pfam PF00136 DNA polymerase family B 763 1105 1.3E-64 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SMART SM00486 133 909 7.4E-111 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SUPERFAMILY SSF53098 1 346 1.71E-87 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:3.10.28.10 522 686 2.8E-9 T 23-10-2018 IPR027434 Homing endonuclease A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 746 768 4.3E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SUPERFAMILY SSF56672 350 407 2.78E-9 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00379 Intein signature 623 635 7.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00379 Intein signature 762 771 7.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00379 Intein signature 744 761 7.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00379 Intein signature 522 534 7.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 761 774 7.8E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 843 855 7.8E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 895 903 7.8E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 763 1104 1.7E-116 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:1.10.287.690 807 859 3.4E-63 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:3.90.1600.10 369 410 2.7E-9 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SUPERFAMILY SSF55608 611 721 1.09E-11 T 23-10-2018 IPR027434 Homing endonuclease A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:1.10.132.60 966 1132 4.4E-61 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Gene3D G3DSA:3.90.1600.10 763 954 3.4E-63 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Pfam PF03104 DNA polymerase family B, exonuclease domain 131 278 1.7E-34 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 Pfam PF03104 DNA polymerase family B, exonuclease domain 25 129 7.3E-12 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SUPERFAMILY SSF56672 767 1118 5.0E-107 T 23-10-2018 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SMART SM00306 406 489 8.2E-9 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SMART SM00305 727 773 5.3E-9 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_00345 cc76e2e3c78b15bddeb24eba96955b45 1134 SUPERFAMILY SSF51294 408 768 9.16E-20 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Pfam PF02540 NAD synthase 5 84 1.4E-6 T 23-10-2018 IPR022310 NAD/GMP synthase A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Pfam PF02540 NAD synthase 157 186 6.9E-5 T 23-10-2018 IPR022310 NAD/GMP synthase A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 SUPERFAMILY SSF52402 2 222 2.43E-54 T 23-10-2018 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Gene3D G3DSA:3.40.50.620 2 189 2.6E-77 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Pfam PF00958 GMP synthase C terminal domain 221 306 4.5E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 9.5E-149 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Gene3D G3DSA:3.30.300.10 190 307 1.8E-52 T 23-10-2018 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 SUPERFAMILY SSF54810 189 307 3.01E-44 T 23-10-2018 A3L12_03175 0a2716ad163b4bafe7cea6c28b3e8b5c 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.344 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L12_07705 28c95f85dd1bd71a3103fbb6b7759abd 290 Gene3D G3DSA:3.30.2010.10 61 150 1.1E-32 T 23-10-2018 A3L12_07705 28c95f85dd1bd71a3103fbb6b7759abd 290 Pfam PF01435 Peptidase family M48 67 282 1.6E-36 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L12_07705 28c95f85dd1bd71a3103fbb6b7759abd 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 29.857 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 SUPERFAMILY SSF53383 2 381 1.14E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 Gene3D G3DSA:3.90.1150.10 5 374 4.8E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 52.164 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 67 331 1.1E-31 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 378 2.3E-167 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L12_00195 248ea697808fb9ccecaae07bc856e0a8 385 Gene3D G3DSA:3.40.640.10 40 290 4.8E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 SUPERFAMILY SSF52029 215 381 1.05E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 Gene3D G3DSA:3.50.7.10 221 372 6.2E-215 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 SUPERFAMILY SSF48592 20 527 4.32E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 Gene3D G3DSA:1.10.560.10 31 525 6.2E-215 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 Gene3D G3DSA:3.30.260.10 150 408 6.2E-215 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 43 55 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 62 80 3.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 40 56 3.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 376 398 3.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 410 422 3.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 92 111 3.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 92 100 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 64 80 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 SUPERFAMILY SSF54849 152 408 2.08E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 Pfam PF00118 TCP-1/cpn60 chaperonin family 38 528 2.5E-184 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L12_07710 1c84ad3a0dbaa0a2b86de4bd3560c956 553 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 11 528 7.6E-240 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L12_03905 688ba7217a4baa628d4fe3f0a1e53837 261 Pfam PF03437 BtpA family 5 253 1.1E-102 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L12_03905 688ba7217a4baa628d4fe3f0a1e53837 261 SUPERFAMILY SSF51366 9 251 8.24E-27 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L12_03905 688ba7217a4baa628d4fe3f0a1e53837 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 3.5E-105 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L12_03905 688ba7217a4baa628d4fe3f0a1e53837 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 3.0E-69 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L12_03905 688ba7217a4baa628d4fe3f0a1e53837 261 PIRSF PIRSF005956 1 259 3.9E-96 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L12_02285 d85d2c8bc30795a7f3e1fd7364ee48d4 418 Gene3D G3DSA:3.90.1150.10 34 409 2.1E-163 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_02285 d85d2c8bc30795a7f3e1fd7364ee48d4 418 Pfam PF00155 Aminotransferase class I and II 57 405 6.2E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_02285 d85d2c8bc30795a7f3e1fd7364ee48d4 418 Gene3D G3DSA:3.40.640.10 79 304 2.1E-163 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_02285 d85d2c8bc30795a7f3e1fd7364ee48d4 418 SUPERFAMILY SSF53383 16 411 1.73E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 SMART SM00654 4 206 2.3E-101 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 7.0E-65 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 PIRSF PIRSF006413 2 228 3.1E-77 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 Gene3D G3DSA:3.75.10.10 1 227 5.3E-78 T 23-10-2018 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 93.827 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 SUPERFAMILY SSF55909 3 226 6.47E-73 T 23-10-2018 A3L12_06530 f29c3a88bb110af7768f362a6cf8e8ee 228 Pfam PF01912 eIF-6 family 5 206 3.3E-67 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L12_06015 d4a04c7bb9b2aff4733c4b179b6047fa 209 SUPERFAMILY SSF160975 26 202 5.62E-87 T 23-10-2018 A3L12_06015 d4a04c7bb9b2aff4733c4b179b6047fa 209 Gene3D G3DSA:2.40.50.140 26 95 7.7E-21 T 23-10-2018 A3L12_06015 d4a04c7bb9b2aff4733c4b179b6047fa 209 Pfam PF04919 Protein of unknown function (DUF655) 26 201 9.8E-69 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A3L12_06015 d4a04c7bb9b2aff4733c4b179b6047fa 209 Gene3D G3DSA:1.10.150.280 96 193 7.2E-41 T 23-10-2018 A3L12_07125 ddaa47e8e19dc1a51b4d6fe41b4d9d81 83 Pfam PF04457 Protein of unknown function (DUF504) 26 77 4.2E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L12_07125 ddaa47e8e19dc1a51b4d6fe41b4d9d81 83 Hamap MF_01245 UPF0248 protein . 10 79 19.026 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 2.1E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 SUPERFAMILY SSF54862 49 123 2.62E-17 T 23-10-2018 A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 Gene3D G3DSA:3.30.70.20 63 115 4.7E-9 T 23-10-2018 A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 Pfam PF13187 4Fe-4S dicluster domain 68 114 2.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_07275 e304827c8f8852cce26e3dd4f7005ab9 286 SUPERFAMILY SSF52540 3 284 8.14E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 251 427 1.3E-42 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Gene3D G3DSA:3.30.70.20 569 619 5.1E-10 T 23-10-2018 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Pfam PF01472 PUA domain 134 204 7.1E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 SUPERFAMILY SSF54862 565 620 1.2E-12 T 23-10-2018 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Gene3D G3DSA:3.40.50.620 212 464 3.1E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 SUPERFAMILY SSF52402 223 414 2.79E-46 T 23-10-2018 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 95 203 1.9E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 573 584 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Gene3D G3DSA:2.30.130.10 130 207 5.5E-16 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 Pfam PF12838 4Fe-4S dicluster domain 573 615 6.5E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 604 615 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 SUPERFAMILY SSF88697 132 204 2.32E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_07055 f846081a380de26bd193b7c7ee295cb5 628 SMART SM00359 133 207 7.3E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.524 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Gene3D G3DSA:1.10.8.60 310 381 1.7E-30 T 23-10-2018 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 SUPERFAMILY SSF52540 134 386 4.67E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Gene3D G3DSA:3.40.50.300 129 309 6.8E-70 T 23-10-2018 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 380 2.5E-198 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 SMART SM00382 172 311 2.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 6.2E-43 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 122 4.8E-8 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A3L12_03665 4ddf50114ff283d415c0bd2b5a6f5f69 398 Gene3D G3DSA:2.40.50.140 25 128 8.8E-27 T 23-10-2018 A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 Gene3D G3DSA:3.30.2130.30 1 149 1.3E-23 T 23-10-2018 A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 SMART SM00981 60 149 3.0E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 6.2E-80 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 SUPERFAMILY SSF75217 188 336 2.22E-19 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 Pfam PF02926 THUMP domain 33 148 2.5E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_05530 49f102d55c6c381f7c47948d3cb9b727 348 SUPERFAMILY SSF143437 4 147 5.76E-25 T 23-10-2018 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 11 456 1.4E-233 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 PIRSF PIRSF015883 1 456 4.9E-197 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 Gene3D G3DSA:3.30.1110.20 18 198 1.3E-156 T 23-10-2018 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 4 456 44.123 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 13 447 2.2E-109 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 SUPERFAMILY SSF53613 10 455 4.81E-155 T 23-10-2018 IPR029056 Ribokinase-like A3L12_06865 a86fba857b5fdefeb982ff8738d01f5c 459 Gene3D G3DSA:3.40.1190.20 13 446 1.3E-156 T 23-10-2018 IPR029056 Ribokinase-like A3L12_07665 849c8986f249558723cc3f7ca11bfb3c 214 SUPERFAMILY SSF48317 13 193 8.76E-30 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L12_07665 849c8986f249558723cc3f7ca11bfb3c 214 Pfam PF01569 PAP2 superfamily 80 188 2.7E-17 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L12_07665 849c8986f249558723cc3f7ca11bfb3c 214 Gene3D G3DSA:1.20.144.10 108 198 1.0E-14 T 23-10-2018 A3L12_07665 849c8986f249558723cc3f7ca11bfb3c 214 SMART SM00014 79 189 2.6E-4 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L12_03675 68cb2acb7301877f4be722c5d77f82ee 159 SUPERFAMILY SSF48452 8 100 1.26E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_03675 68cb2acb7301877f4be722c5d77f82ee 159 Gene3D G3DSA:1.25.40.10 12 137 4.9E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 390 2.7E-117 T 23-10-2018 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 65.303 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 Gene3D G3DSA:3.20.20.140 44 408 4.4E-105 T 23-10-2018 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 SUPERFAMILY SSF51338 17 62 2.59E-7 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 SUPERFAMILY SSF51556 53 335 3.58E-76 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 SUPERFAMILY SSF51338 336 400 6.61E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 Pfam PF01979 Amidohydrolase family 49 105 1.3E-11 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 Pfam PF01979 Amidohydrolase family 263 388 3.9E-9 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L12_02505 bce928eec0ecf98a76a455f923ec7e4e 410 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 73 379 7.2E-102 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 7.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 7.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 7.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 7.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 Gene3D G3DSA:1.10.240.10 256 381 8.8E-42 T 23-10-2018 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 45.812 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 SUPERFAMILY SSF52374 4 368 2.73E-89 T 23-10-2018 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 Pfam PF00579 tRNA synthetases class I (W and Y) 74 346 2.9E-24 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00035 b53224c3d1dff732c9af8df96b40a30a 383 Gene3D G3DSA:3.40.50.620 1 255 4.5E-100 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03850 6cca725a298304f339c01452d140ee2d 263 Gene3D G3DSA:3.40.830.10 1 262 1.9E-71 T 23-10-2018 A3L12_03850 6cca725a298304f339c01452d140ee2d 263 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 240 9.6E-13 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A3L12_03850 6cca725a298304f339c01452d140ee2d 263 SUPERFAMILY SSF53213 4 259 1.44E-25 T 23-10-2018 A3L12_00495 0a8cacb51a468b998eab063d7ffa6303 401 PIRSF PIRSF015658 1 401 4.9E-168 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L12_00495 0a8cacb51a468b998eab063d7ffa6303 401 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 399 6.9E-159 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L12_00495 0a8cacb51a468b998eab063d7ffa6303 401 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 395 4.2E-156 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L12_07685 e851e2112fc72dc405a24ff3e5d3f2a3 180 Pfam PF13302 Acetyltransferase (GNAT) domain 17 149 6.7E-27 T 23-10-2018 IPR000182 GNAT domain A3L12_07685 e851e2112fc72dc405a24ff3e5d3f2a3 180 SUPERFAMILY SSF55729 2 173 1.72E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_07685 e851e2112fc72dc405a24ff3e5d3f2a3 180 Gene3D G3DSA:3.40.630.30 1 179 1.0E-43 T 23-10-2018 A3L12_02635 4e87594844c9e9783d100cd0d860a44f 415 SUPERFAMILY SSF161098 9 67 3.14E-5 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02635 4e87594844c9e9783d100cd0d860a44f 415 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 224 404 1.9E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_02635 4e87594844c9e9783d100cd0d860a44f 415 Gene3D G3DSA:1.10.3720.10 167 402 8.7E-46 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02635 4e87594844c9e9783d100cd0d860a44f 415 Gene3D G3DSA:1.10.3720.10 2 80 7.8E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02635 4e87594844c9e9783d100cd0d860a44f 415 SUPERFAMILY SSF161098 172 414 1.44E-52 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01580 c44711423f926c11200b40bff7ef3c31 459 SMART SM00493 200 269 2.0E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01580 c44711423f926c11200b40bff7ef3c31 459 Gene3D G3DSA:3.40.1360.10 198 292 1.0E-12 T 23-10-2018 A3L12_01580 c44711423f926c11200b40bff7ef3c31 459 SUPERFAMILY SSF56731 199 312 2.88E-11 T 23-10-2018 A3L12_01580 c44711423f926c11200b40bff7ef3c31 459 Pfam PF13662 Toprim domain 201 286 8.3E-13 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01580 c44711423f926c11200b40bff7ef3c31 459 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 458 36.001 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 Gene3D G3DSA:2.40.50.970 1 74 3.5E-31 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 75 5.4E-27 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 Pfam PF01455 HupF/HypC family 1 65 3.0E-28 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 3.1E-11 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 3.1E-11 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 3.1E-11 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site A3L12_01880 3fcaa5c22bf6575569da5234b68b0f6d 82 SUPERFAMILY SSF159127 1 76 7.59E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 1.1E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 421 1.4E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 SMART SM00849 14 221 1.2E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 439 1.5E-161 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 Gene3D G3DSA:3.60.15.10 4 439 1.6E-137 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 50.078 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 SUPERFAMILY SSF56281 2 439 2.16E-68 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_00950 0a23be5310966b280a3e3009f337bfaf 440 Gene3D G3DSA:3.40.50.10710 215 374 1.6E-137 T 23-10-2018 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 SUPERFAMILY SSF56059 102 310 5.71E-64 T 23-10-2018 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 Pfam PF06849 Protein of unknown function (DUF1246) 4 113 1.4E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 Gene3D G3DSA:3.40.50.20 1 83 5.3E-29 T 23-10-2018 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 SUPERFAMILY SSF52440 3 96 2.4E-30 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 Gene3D G3DSA:3.30.470.20 85 308 1.1E-68 T 23-10-2018 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 Pfam PF06973 Domain of unknown function (DUF1297) 158 310 5.7E-41 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03075 22f1d7bafba1f7cc18cae70390caee28 310 Gene3D G3DSA:3.30.1490.20 112 165 1.1E-68 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 SUPERFAMILY SSF52540 135 419 9.24E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 Gene3D G3DSA:3.40.50.300 84 261 3.4E-34 T 23-10-2018 A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 Pfam PF00271 Helicase conserved C-terminal domain 305 404 1.7E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 Pfam PF04851 Type III restriction enzyme, res subunit 95 231 1.0E-15 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 SMART SM00490 328 406 1.4E-12 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 Gene3D G3DSA:3.40.50.300 273 452 3.5E-32 T 23-10-2018 A3L12_06080 cd83e1c098d0f9a315b8469de7b2918e 461 SMART SM00487 91 272 1.6E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06555 8f7198a3de69219f053fee3ab0e31120 112 PIRSF PIRSF015730 1 112 8.6E-35 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L12_06555 8f7198a3de69219f053fee3ab0e31120 112 Hamap MF_00026 DNA-binding protein . 3 112 15.783 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A3L12_06555 8f7198a3de69219f053fee3ab0e31120 112 Pfam PF01984 Double-stranded DNA-binding domain 8 110 5.9E-26 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L12_06555 8f7198a3de69219f053fee3ab0e31120 112 Gene3D G3DSA:1.10.8.140 22 112 7.3E-26 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L12_06555 8f7198a3de69219f053fee3ab0e31120 112 SUPERFAMILY SSF46950 8 111 1.02E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Pfam PF00005 ABC transporter 96 238 3.0E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 SUPERFAMILY SSF54862 4 127 6.41E-23 T 23-10-2018 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 SUPERFAMILY SSF52540 96 290 3.52E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Gene3D G3DSA:3.40.50.300 327 589 8.9E-68 T 23-10-2018 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Pfam PF00005 ABC transporter 360 482 1.3E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 48 72 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 150 176 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 75 95 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 20 35 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 103 128 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 PRINTS PR01868 ABC transporter family E signature 134 150 1.1E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 SMART SM00382 363 531 9.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 SMART SM00382 98 286 7.9E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Pfam PF00037 4Fe-4S binding domain 44 66 7.1E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 SUPERFAMILY SSF52540 359 529 5.5E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 1.2E-11 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A3L12_07775 18ef1580afeca7b3e899e4c4ed01ac9d 590 Gene3D G3DSA:3.40.50.300 1 326 9.6E-102 T 23-10-2018 A3L12_06330 8756ff1cb2f8084b3578cb53ce5bf310 241 Gene3D G3DSA:3.40.800.10 47 240 1.1E-17 T 23-10-2018 A3L12_06330 8756ff1cb2f8084b3578cb53ce5bf310 241 PIRSF PIRSF036979 35 231 7.3E-15 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_06330 8756ff1cb2f8084b3578cb53ce5bf310 241 SUPERFAMILY SSF52768 56 229 7.56E-24 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L12_06330 8756ff1cb2f8084b3578cb53ce5bf310 241 Pfam PF00491 Arginase family 56 224 4.6E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 Gene3D G3DSA:2.60.120.1040 74 199 1.3E-21 T 23-10-2018 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 SMART SM00709 25 185 5.4E-74 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 27 192 2.7E-65 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 Pfam PF03367 ZPR1 zinc-finger domain 26 182 2.3E-37 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 26 213 3.7E-59 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L12_00475 7ea04ab1ee144397a65d2ace76da911b 217 Gene3D G3DSA:2.20.25.420 15 70 3.5E-7 T 23-10-2018 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 SMART SM00881 4 98 1.3E-18 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 SUPERFAMILY SSF52210 290 436 1.06E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 1.7E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 Gene3D G3DSA:3.40.50.261 135 286 7.6E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 Gene3D G3DSA:3.40.50.720 1 125 1.2E-28 T 23-10-2018 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 SUPERFAMILY SSF51735 2 126 9.54E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 SUPERFAMILY SSF52210 128 284 5.76E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 Pfam PF13380 CoA binding domain 9 129 4.2E-15 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_04705 d2f1448dcd73f53e364d8e1c9d329b6f 444 Gene3D G3DSA:3.40.50.261 287 441 6.9E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 Pfam PF01918 Alba 6 66 6.4E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 28.076 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 Gene3D G3DSA:3.30.110.20 2 90 7.5E-39 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 SUPERFAMILY SSF82704 5 90 2.75E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 89 1.4E-45 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 6.0E-39 T 23-10-2018 A3L12_07190 f1e9142210408b1f7b646405b3e56cc6 91 PIRSF PIRSF028732 1 91 1.3E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 SUPERFAMILY SSF52156 334 460 1.02E-34 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Gene3D G3DSA:2.40.30.10 232 349 6.5E-41 T 23-10-2018 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 6.8E-31 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 1.3E-28 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 43.562 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 SUPERFAMILY SSF52540 5 288 1.99E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 145 2.6E-19 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 SUPERFAMILY SSF50447 465 592 3.53E-25 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Gene3D G3DSA:2.40.30.10 466 556 3.1E-30 T 23-10-2018 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Gene3D G3DSA:3.40.50.10050 350 457 3.5E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Gene3D G3DSA:3.40.50.300 2 226 1.6E-63 T 23-10-2018 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 1.6E-12 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 Pfam PF11987 Translation-initiation factor 2 344 446 1.8E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A3L12_07095 35b3c417fc0b27d51256499ac1035116 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 594 2.1E-241 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 SUPERFAMILY SSF50249 4 57 4.8E-8 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 Gene3D G3DSA:3.40.1350.30 112 257 2.3E-116 T 23-10-2018 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 Gene3D G3DSA:2.40.50.140 2 71 4.5E-14 T 23-10-2018 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 247 414 6.6E-23 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 3.2E-84 T 23-10-2018 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 Gene3D G3DSA:3.40.50.150 73 410 2.3E-116 T 23-10-2018 A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 SUPERFAMILY SSF53335 60 413 2.02E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_04230 4174dd22d298445f85aeae1188c966cc 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L12_05170 e1199aebb6646770658f38754c1f5365 222 Gene3D G3DSA:1.10.150.240 17 86 3.3E-32 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 190 5.1E-24 T 23-10-2018 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.7E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 5.7E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 5.7E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 5.7E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 188 1.2E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_05170 e1199aebb6646770658f38754c1f5365 222 Gene3D G3DSA:3.40.50.1000 6 194 3.3E-32 T 23-10-2018 IPR023214 HAD superfamily A3L12_05170 e1199aebb6646770658f38754c1f5365 222 SUPERFAMILY SSF56784 1 216 3.8E-41 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_05170 e1199aebb6646770658f38754c1f5365 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 184 3.8E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_06305 8b1235b8c764344c0c77799bb61051eb 206 Pfam PF01966 HD domain 35 137 1.7E-18 T 23-10-2018 IPR006674 HD domain A3L12_06305 8b1235b8c764344c0c77799bb61051eb 206 Gene3D G3DSA:1.10.3210.50 13 206 1.2E-62 T 23-10-2018 A3L12_06305 8b1235b8c764344c0c77799bb61051eb 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 106 1.2E-8 T 23-10-2018 IPR006675 HDIG domain A3L12_06305 8b1235b8c764344c0c77799bb61051eb 206 SUPERFAMILY SSF109604 14 204 6.02E-60 T 23-10-2018 A3L12_06305 8b1235b8c764344c0c77799bb61051eb 206 SMART SM00471 30 147 8.2E-12 T 23-10-2018 IPR003607 HD/PDEase domain A3L12_02330 da26c8181358b57de24f5781517e1647 150 Gene3D G3DSA:1.10.10.10 2 55 2.6E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_02330 da26c8181358b57de24f5781517e1647 150 SUPERFAMILY SSF54909 65 150 9.12E-22 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_02330 da26c8181358b57de24f5781517e1647 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.7E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_02330 da26c8181358b57de24f5781517e1647 150 SMART SM00344 5 111 1.8E-46 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_02330 da26c8181358b57de24f5781517e1647 150 SUPERFAMILY SSF46785 5 65 6.54E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_02330 da26c8181358b57de24f5781517e1647 150 Gene3D G3DSA:3.30.70.920 57 150 2.1E-27 T 23-10-2018 A3L12_02330 da26c8181358b57de24f5781517e1647 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 5.6E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_02330 da26c8181358b57de24f5781517e1647 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 5.6E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_02330 da26c8181358b57de24f5781517e1647 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 5.6E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_02330 da26c8181358b57de24f5781517e1647 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 1.5E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_02465 0742d4f88633a680f1bb85fb40ae9724 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 18.661 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A3L12_02465 0742d4f88633a680f1bb85fb40ae9724 102 Gene3D G3DSA:3.40.50.10580 1 102 2.0E-32 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02465 0742d4f88633a680f1bb85fb40ae9724 102 SUPERFAMILY SSF159468 3 100 2.35E-19 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02465 0742d4f88633a680f1bb85fb40ae9724 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 5.0E-18 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 Pfam PF01907 Ribosomal protein L37e 3 53 1.2E-19 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 58 19.759 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 7.0E-16 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 SUPERFAMILY SSF57829 1 55 4.39E-17 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_05080 82b9d8bb75298b542ff1a46a03140c0c 63 Gene3D G3DSA:2.20.25.30 1 58 1.8E-18 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_04895 eec57d796226c4a7fe580928865326e2 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 1.4E-47 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L12_04895 eec57d796226c4a7fe580928865326e2 231 Pfam PF02654 Cobalamin-5-phosphate synthase 6 221 9.1E-40 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L12_04895 eec57d796226c4a7fe580928865326e2 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 29.45 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L12_00780 f4df29f12b95268165e68f90130a6033 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.775 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A3L12_00780 f4df29f12b95268165e68f90130a6033 121 SUPERFAMILY SSF52080 6 120 1.96E-30 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L12_00780 f4df29f12b95268165e68f90130a6033 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 2.3E-16 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L12_00780 f4df29f12b95268165e68f90130a6033 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00780 f4df29f12b95268165e68f90130a6033 121 Gene3D G3DSA:3.100.10.10 6 121 3.6E-40 T 23-10-2018 A3L12_06535 f256f79244a4d998a2f573a7a9298bc7 76 SUPERFAMILY SSF160374 1 74 3.4E-23 T 23-10-2018 A3L12_06535 f256f79244a4d998a2f573a7a9298bc7 76 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 57 1.0E-14 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A3L12_06535 f256f79244a4d998a2f573a7a9298bc7 76 Gene3D G3DSA:3.10.20.10 3 75 5.2E-25 T 23-10-2018 A3L12_06535 f256f79244a4d998a2f573a7a9298bc7 76 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 17.572 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06535 f256f79244a4d998a2f573a7a9298bc7 76 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 4.4E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05515 fb4430acde34d89baa458923921c17e9 102 PIRSF PIRSF029904 1 102 1.2E-34 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A3L12_05515 fb4430acde34d89baa458923921c17e9 102 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 94 2.3E-13 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L12_05515 fb4430acde34d89baa458923921c17e9 102 Gene3D G3DSA:1.10.287.1080 1 102 9.2E-28 T 23-10-2018 A3L12_05515 fb4430acde34d89baa458923921c17e9 102 SUPERFAMILY SSF101386 1 91 1.13E-21 T 23-10-2018 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 SUPERFAMILY SSF52317 2 219 1.29E-75 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_03155 328f9f609091d4077448e220e097b0ae 222 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 218 44.477 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 PIRSF PIRSF001586 1 222 1.1E-82 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 219 5.9E-46 T 23-10-2018 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 3 218 4.1E-94 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 SMART SM01211 1 220 4.5E-126 T 23-10-2018 A3L12_03155 328f9f609091d4077448e220e097b0ae 222 Gene3D G3DSA:3.40.50.880 1 222 1.6E-76 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_04270 17212cc634f8625742f98cb248cbe017 531 Pfam PF03553 Na+/H+ antiporter family 156 486 9.0E-76 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A3L12_07140 56c6098f1189ff353983dc10771d6998 196 SUPERFAMILY SSF109755 3 98 2.22E-15 T 23-10-2018 A3L12_07140 56c6098f1189ff353983dc10771d6998 196 Gene3D G3DSA:1.20.58.220 1 110 3.6E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_07140 56c6098f1189ff353983dc10771d6998 196 SUPERFAMILY SSF116726 103 181 3.4E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_07140 56c6098f1189ff353983dc10771d6998 196 Pfam PF02080 TrkA-C domain 118 176 1.8E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L12_07140 56c6098f1189ff353983dc10771d6998 196 Pfam PF01895 PhoU domain 11 94 1.3E-10 T 23-10-2018 IPR026022 PhoU domain A3L12_07140 56c6098f1189ff353983dc10771d6998 196 Gene3D G3DSA:3.30.70.1450 111 190 1.2E-21 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 SMART SM00938 4 97 3.7E-39 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 PRINTS PR00340 P-II protein signature 2 17 7.5E-25 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 PRINTS PR00340 P-II protein signature 75 95 7.5E-25 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 PRINTS PR00340 P-II protein signature 44 67 7.5E-25 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 ProSitePatterns PS00638 P-II protein C-terminal region signature. 75 88 - T 23-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 Gene3D G3DSA:3.30.70.120 1 105 3.7E-37 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.6E-28 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L12_01020 72b793c88c07dce3dd71280dcc9a85d4 105 SUPERFAMILY SSF54913 1 104 5.08E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L12_05420 efd74803d841dc3ffc69a60a303383af 216 Gene3D G3DSA:1.20.58.2140 3 201 2.9E-64 T 23-10-2018 A3L12_05420 efd74803d841dc3ffc69a60a303383af 216 SUPERFAMILY SSF74784 2 182 1.01E-37 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A3L12_05420 efd74803d841dc3ffc69a60a303383af 216 Pfam PF01997 Translin family 21 181 1.3E-11 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 SMART SM00864 2 199 5.1E-31 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 Gene3D G3DSA:3.40.50.1440 2 363 2.4E-84 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 6 168 1.4E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 SUPERFAMILY SSF52490 2 199 4.32E-39 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.078 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.1E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.1E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_03230 57bcafb212045b9d3c3dff9af2b9a990 383 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.1E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 2.7E-74 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 Gene3D G3DSA:3.40.50.10490 213 406 3.1E-57 T 23-10-2018 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 Gene3D G3DSA:3.20.20.70 1 210 6.7E-77 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 SMART SM00934 2 203 8.8E-46 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 SUPERFAMILY SSF53697 215 404 4.45E-38 T 23-10-2018 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 5.8E-84 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 Pfam PF01380 SIS domain 246 347 2.7E-20 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 5.2E-29 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_06325 a4baf06b856f45033c9a92317378dec4 406 SUPERFAMILY SSF51366 2 214 8.08E-46 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L12_03855 a8d011b6186ba2693e43e5b4d4eef4b0 449 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 252 299 4.0E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A3L12_03855 a8d011b6186ba2693e43e5b4d4eef4b0 449 SUPERFAMILY SSF52540 125 292 9.11E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03855 a8d011b6186ba2693e43e5b4d4eef4b0 449 Gene3D G3DSA:3.40.50.720 3 132 1.1E-8 T 23-10-2018 A3L12_03855 a8d011b6186ba2693e43e5b4d4eef4b0 449 Gene3D G3DSA:3.40.50.300 207 304 6.0E-8 T 23-10-2018 A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 Pfam PF01871 AMMECR1 13 190 2.8E-53 T 23-10-2018 IPR002733 AMMECR1 domain A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 1.3E-56 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 198 3.0E-68 T 23-10-2018 IPR023473 AMMECR1 A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 SUPERFAMILY SSF143447 4 202 1.07E-68 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 Gene3D G3DSA:3.30.700.20 6 197 4.3E-72 T 23-10-2018 IPR027485 AMMECR1, N-terminal A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 Hamap MF_00645 Protein . 5 188 41.212 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A3L12_00335 2ad36809f83a9af3036fde5c65485911 205 Gene3D G3DSA:3.30.1490.150 113 186 4.3E-72 T 23-10-2018 A3L12_07890 1bfd5073204d16c673b61756aec11130 413 Pfam PF04409 Protein of unknown function (DUF530) 10 253 1.4E-21 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A3L12_08180 333c5783b9f28e34a2e6ed0132ad21d2 163 Gene3D G3DSA:3.30.70.20 91 146 1.3E-9 T 23-10-2018 A3L12_08180 333c5783b9f28e34a2e6ed0132ad21d2 163 Pfam PF12838 4Fe-4S dicluster domain 104 142 1.8E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_08180 333c5783b9f28e34a2e6ed0132ad21d2 163 SUPERFAMILY SSF54862 98 142 1.35E-12 T 23-10-2018 A3L12_08180 333c5783b9f28e34a2e6ed0132ad21d2 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_06065 defce41087aa335321d19a6605e53d23 500 Gene3D G3DSA:3.30.930.10 194 499 1.1E-90 T 23-10-2018 A3L12_06065 defce41087aa335321d19a6605e53d23 500 SUPERFAMILY SSF55681 224 497 4.98E-59 T 23-10-2018 A3L12_06065 defce41087aa335321d19a6605e53d23 500 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 179 497 2.8E-93 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L12_06065 defce41087aa335321d19a6605e53d23 500 Pfam PF01409 tRNA synthetases class II core domain (F) 224 495 4.7E-81 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L12_06065 defce41087aa335321d19a6605e53d23 500 Gene3D G3DSA:1.10.10.10 1 112 2.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06065 defce41087aa335321d19a6605e53d23 500 SUPERFAMILY SSF46785 2 72 5.93E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06065 defce41087aa335321d19a6605e53d23 500 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 497 37.527 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 Pfam PF01266 FAD dependent oxidoreductase 5 366 6.5E-66 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 SUPERFAMILY SSF54373 229 327 5.89E-10 T 23-10-2018 A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 SUPERFAMILY SSF51905 3 398 2.03E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 Gene3D G3DSA:3.30.9.10 90 328 1.1E-105 T 23-10-2018 A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 Gene3D G3DSA:1.10.10.1100 399 480 2.2E-15 T 23-10-2018 A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 Pfam PF04324 BFD-like [2Fe-2S] binding domain 413 471 2.9E-10 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L12_04125 3abe893ad8371fdfb66f8089cf238881 505 Gene3D G3DSA:3.50.50.60 5 362 1.1E-105 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 Gene3D G3DSA:1.10.1200.240 56 148 9.6E-31 T 23-10-2018 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 Gene3D G3DSA:1.10.1650.10 1 54 2.0E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 25.891 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 Pfam PF01280 Ribosomal protein L19e 2 143 8.4E-59 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 SMART SM01416 1 144 1.1E-87 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00685 a4124ae4206936111c4a9c6c60fcca8c 148 SUPERFAMILY SSF48140 1 141 1.83E-57 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_03615 654ded187d285b6a24bb30d89dae9291 252 SUPERFAMILY SSF52540 3 226 1.9E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03615 654ded187d285b6a24bb30d89dae9291 252 Pfam PF00005 ABC transporter 19 162 8.9E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_03615 654ded187d285b6a24bb30d89dae9291 252 SMART SM00382 28 220 6.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03615 654ded187d285b6a24bb30d89dae9291 252 Gene3D G3DSA:3.40.50.300 1 244 1.1E-67 T 23-10-2018 A3L12_02325 efdda0684159ee599830402ba27488da 166 SUPERFAMILY SSF52317 1 165 1.72E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02325 efdda0684159ee599830402ba27488da 166 Gene3D G3DSA:3.40.50.880 1 166 5.0E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02325 efdda0684159ee599830402ba27488da 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 1.5E-66 T 23-10-2018 IPR006286 Deglycase PfpI A3L12_02325 efdda0684159ee599830402ba27488da 166 Pfam PF01965 DJ-1/PfpI family 1 163 5.7E-59 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Hamap MF_01509 Replication factor C small subunit [rfcS]. 11 325 51.15 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 49 167 7.9E-18 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 SUPERFAMILY SSF48019 235 324 5.78E-24 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 SUPERFAMILY SSF52540 12 227 2.84E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 SMART SM00382 45 176 4.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Gene3D G3DSA:3.40.50.300 2 169 1.7E-62 T 23-10-2018 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Gene3D G3DSA:1.20.272.10 234 326 1.3E-36 T 23-10-2018 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Gene3D G3DSA:1.10.8.60 170 233 4.8E-25 T 23-10-2018 A3L12_03775 ce0d56c8f8ff5cb35f748b57cf06d0b7 326 Pfam PF08542 Replication factor C C-terminal domain 235 320 2.1E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A3L12_00205 9d86ff18280d6cb00d84ff77ee0dad61 81 Pfam PF01998 Protein of unknown function DUF131 33 74 3.6E-13 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.2E-14 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 SUPERFAMILY SSF55129 5 155 1.96E-47 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 1.1E-59 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 Gene3D G3DSA:3.30.1390.20 5 143 2.6E-52 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 Gene3D G3DSA:1.10.15.30 60 114 2.6E-52 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A3L12_00700 daa519399d8c72a1ed56a9e217e5982b 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 77.235 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L12_01050 70c6bc2adc3bfe7a3dc343f6ff560577 387 Gene3D G3DSA:3.40.50.300 1 183 5.0E-11 T 23-10-2018 A3L12_07545 4380fa7206f4b44485db6527af2b5d4c 232 SUPERFAMILY SSF52540 4 221 3.0E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07545 4380fa7206f4b44485db6527af2b5d4c 232 Gene3D G3DSA:3.40.50.300 4 232 1.8E-46 T 23-10-2018 A3L12_07545 4380fa7206f4b44485db6527af2b5d4c 232 Pfam PF06745 KaiC 15 225 5.0E-19 T 23-10-2018 IPR014774 KaiC-like domain A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.371 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 PIRSF PIRSF002122 1 215 1.3E-47 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 2.9E-88 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 Gene3D G3DSA:1.10.455.10 15 215 1.1E-78 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 Pfam PF00177 Ribosomal protein S7p/S5e 54 215 6.7E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A3L12_01740 c632f3f61adee74a4a0a15f1b53f7242 215 SUPERFAMILY SSF47973 16 215 2.35E-62 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L12_03830 0eaa48bf0e3630f1927db9465200b239 338 Pfam PF01032 FecCD transport family 13 330 2.1E-82 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L12_03830 0eaa48bf0e3630f1927db9465200b239 338 SUPERFAMILY SSF81345 3 330 1.03E-75 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L12_03830 0eaa48bf0e3630f1927db9465200b239 338 Gene3D G3DSA:1.10.3470.10 2 335 7.6E-90 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L12_00715 343d46550dc74bd7e1e0310dd0c4054e 196 Gene3D G3DSA:3.40.50.300 2 189 6.2E-56 T 23-10-2018 A3L12_00715 343d46550dc74bd7e1e0310dd0c4054e 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 42.938 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L12_00715 343d46550dc74bd7e1e0310dd0c4054e 196 SUPERFAMILY SSF52540 1 188 2.8E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00715 343d46550dc74bd7e1e0310dd0c4054e 196 Pfam PF13207 AAA domain 8 145 3.0E-36 T 23-10-2018 A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 Gene3D G3DSA:1.10.10.10 83 159 1.5E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 SUPERFAMILY SSF46785 3 81 1.06E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 7.9E-31 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 Gene3D G3DSA:1.10.10.10 2 82 9.5E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 5.8E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 SUPERFAMILY SSF46785 84 152 2.25E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03500 26227fc0c41acd0fce5531934c13b28a 191 PIRSF PIRSF019345 1 191 6.8E-48 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L12_02305 233cb02f56af1fe9aada5f6286b73e78 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 207 6.3E-63 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L12_02305 233cb02f56af1fe9aada5f6286b73e78 213 Pfam PF01914 MarC family integral membrane protein 6 211 4.0E-60 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 SUPERFAMILY SSF54631 7 153 8.73E-22 T 23-10-2018 A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 Gene3D G3DSA:3.10.580.10 11 156 1.4E-19 T 23-10-2018 A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 Pfam PF00571 CBS domain 98 152 2.0E-9 T 23-10-2018 IPR000644 CBS domain A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 Pfam PF00571 CBS domain 25 72 4.5E-4 T 23-10-2018 IPR000644 CBS domain A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 SMART SM00116 105 152 5.3E-6 T 23-10-2018 IPR000644 CBS domain A3L12_05925 a2d2c451c55c282aeee078bf459e5f67 164 SMART SM00116 24 72 4.8 T 23-10-2018 IPR000644 CBS domain A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 12 95 2.8E-33 T 23-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 SUPERFAMILY SSF52794 10 105 3.14E-36 T 23-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 136 463 2.3E-127 T 23-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 Pfam PF02378 Phosphotransferase system, EIIC 148 410 6.2E-17 T 23-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 Gene3D G3DSA:3.40.50.2300 2 109 1.9E-41 T 23-10-2018 A3L12_04785 7f88f22fa165dd64f7c48efbd372b9b9 476 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 13 101 2.2E-21 T 23-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A3L12_07100 fe4bcfa62e6b0da880c27b17b682378d 515 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 6 505 2.9E-95 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A3L12_07100 fe4bcfa62e6b0da880c27b17b682378d 515 Gene3D G3DSA:3.20.20.20 167 370 2.6E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L12_07100 fe4bcfa62e6b0da880c27b17b682378d 515 SUPERFAMILY SSF51717 164 386 3.01E-26 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 1.1E-8 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 Gene3D G3DSA:3.40.50.720 7 327 3.3E-89 T 23-10-2018 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 PIRSF PIRSF036497 1 335 1.3E-81 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 Pfam PF00742 Homoserine dehydrogenase 156 327 1.0E-45 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 SUPERFAMILY SSF55347 156 314 3.53E-38 T 23-10-2018 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 Gene3D G3DSA:3.30.360.10 167 310 3.3E-89 T 23-10-2018 A3L12_00485 ef2504fd4e1e6f257d4fb77924c90557 336 SUPERFAMILY SSF51735 3 177 2.91E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 Pfam PF00831 Ribosomal L29 protein 4 61 4.2E-18 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.578 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 SUPERFAMILY SSF46561 1 61 1.31E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 Gene3D G3DSA:1.10.287.310 1 66 1.3E-19 T 23-10-2018 A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00625 a689c639977c159f8e49f20f191f2f97 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 1.1E-19 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06055 4e073a6c0752eb21698b4dc6c3d5bf47 247 SUPERFAMILY SSF52540 1 244 5.1E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06055 4e073a6c0752eb21698b4dc6c3d5bf47 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 2.2E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L12_06055 4e073a6c0752eb21698b4dc6c3d5bf47 247 Gene3D G3DSA:3.40.50.300 2 241 1.4E-48 T 23-10-2018 A3L12_07755 2d3ccc2727518adffc2b99c912fac4d2 280 SUPERFAMILY SSF103481 182 273 1.57E-7 T 23-10-2018 A3L12_07755 2d3ccc2727518adffc2b99c912fac4d2 280 Pfam PF00892 EamA-like transporter family 6 139 5.0E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_07755 2d3ccc2727518adffc2b99c912fac4d2 280 Pfam PF00892 EamA-like transporter family 149 271 1.4E-12 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_07755 2d3ccc2727518adffc2b99c912fac4d2 280 SUPERFAMILY SSF103481 41 143 1.23E-12 T 23-10-2018 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 Pfam PF01048 Phosphorylase superfamily 3 237 2.1E-48 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.26 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 3 238 4.5E-101 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 Gene3D G3DSA:3.40.50.1580 1 257 3.2E-102 T 23-10-2018 A3L12_04835 7695c5adc0792b58ed8b5aa05273a745 257 SUPERFAMILY SSF53167 1 255 7.2E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L12_03865 b53b6f1e2cf4a4d2cb7ce5cc7419d691 296 Gene3D G3DSA:3.40.225.10 123 296 3.0E-43 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L12_03865 b53b6f1e2cf4a4d2cb7ce5cc7419d691 296 SUPERFAMILY SSF47413 14 66 3.55E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_03865 b53b6f1e2cf4a4d2cb7ce5cc7419d691 296 SUPERFAMILY SSF53639 125 294 1.41E-45 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L12_03865 b53b6f1e2cf4a4d2cb7ce5cc7419d691 296 Pfam PF10120 Thiamine-phosphate synthase 135 290 8.2E-45 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_03475 3a26eaec7dc27939bf24b1f9678162a4 276 Pfam PF01040 UbiA prenyltransferase family 22 259 8.0E-45 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L12_03475 3a26eaec7dc27939bf24b1f9678162a4 276 Gene3D G3DSA:1.10.357.140 9 156 5.1E-15 T 23-10-2018 A3L12_03475 3a26eaec7dc27939bf24b1f9678162a4 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.094 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A3L12_01920 e7c5372b260ca00ebd25224e2f29ca74 256 Gene3D G3DSA:3.40.210.20 5 222 5.0E-55 T 23-10-2018 A3L12_01920 e7c5372b260ca00ebd25224e2f29ca74 256 Pfam PF15515 MvaI/BcnI restriction endonuclease family 8 222 4.7E-46 T 23-10-2018 IPR029127 MvaI/BcnI restriction endonuclease A3L12_01920 e7c5372b260ca00ebd25224e2f29ca74 256 Gene3D G3DSA:2.60.40.2490 65 216 5.0E-55 T 23-10-2018 A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 PIRSF PIRSF038984 133 463 3.2E-25 T 23-10-2018 IPR028348 FAD dependent protein A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 PIRSF PIRSF038984 2 87 1.7E-9 T 23-10-2018 IPR028348 FAD dependent protein A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 41 7.7E-6 T 23-10-2018 A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 Gene3D G3DSA:3.50.50.60 416 456 1.4E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 SUPERFAMILY SSF51905 1 459 1.86E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 Gene3D G3DSA:3.50.50.60 133 232 3.1E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 Gene3D G3DSA:3.50.50.60 2 90 6.5E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 4.8E-10 T 23-10-2018 A3L12_00245 b712edfedc2e7b2dd22e9c21638cc844 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.8E-10 T 23-10-2018 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 Pfam PF00557 Metallopeptidase family M24 8 287 1.0E-45 T 23-10-2018 IPR000994 Peptidase M24 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.786 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 SUPERFAMILY SSF55920 3 295 7.46E-68 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 2.2E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 2.2E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.2E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 2.2E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 Gene3D G3DSA:1.10.10.10 196 272 4.8E-107 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 3 295 1.0E-118 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 SUPERFAMILY SSF46785 196 271 5.71E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06205 5334f61ac32e8345ecdb144866eed7d0 295 Gene3D G3DSA:3.90.230.10 9 286 4.8E-107 T 23-10-2018 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 SUPERFAMILY SSF52374 2 165 2.82E-37 T 23-10-2018 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 167 3.9E-69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 Pfam PF01467 Cytidylyltransferase-like 5 135 3.3E-17 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 61 2.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 186 90.69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L12_03585 c297f86117d9eee644f3761d008923c1 186 Gene3D G3DSA:3.40.50.620 1 177 2.5E-54 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_00230 a5e3338d1e62e748d9af30135b3d9c9f 307 Gene3D G3DSA:3.40.50.620 3 305 8.5E-88 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_00230 a5e3338d1e62e748d9af30135b3d9c9f 307 SUPERFAMILY SSF52402 26 247 5.07E-49 T 23-10-2018 A3L12_00230 a5e3338d1e62e748d9af30135b3d9c9f 307 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 194 293 1.9E-22 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L12_00230 a5e3338d1e62e748d9af30135b3d9c9f 307 Pfam PF01171 PP-loop family 52 223 1.1E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L12_00230 a5e3338d1e62e748d9af30135b3d9c9f 307 PIRSF PIRSF004976 1 303 1.2E-91 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 SUPERFAMILY SSF52540 4 244 2.93E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 Pfam PF00005 ABC transporter 19 161 4.0E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 Gene3D G3DSA:2.40.50.100 238 346 9.0E-8 T 23-10-2018 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 Gene3D G3DSA:3.40.50.300 1 237 5.6E-78 T 23-10-2018 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 SUPERFAMILY SSF50331 237 350 4.54E-14 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 Pfam PF08402 TOBE domain 275 349 6.3E-8 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 Gene3D G3DSA:2.40.50.140 293 340 9.0E-8 T 23-10-2018 A3L12_06945 f1d2deb74869a6f322a3db5facc4df82 354 SMART SM00382 28 211 4.2E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 PRINTS PR00990 Ribokinase signature 200 211 5.7E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 PRINTS PR00990 Ribokinase signature 161 176 5.7E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 PRINTS PR00990 Ribokinase signature 23 42 5.7E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 SUPERFAMILY SSF53613 4 273 2.34E-54 T 23-10-2018 IPR029056 Ribokinase-like A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 Pfam PF00294 pfkB family carbohydrate kinase 5 273 2.0E-40 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 Gene3D G3DSA:3.40.1190.20 2 275 2.0E-60 T 23-10-2018 IPR029056 Ribokinase-like A3L12_00155 6c8447b8860f9bdec2c100232ae13941 276 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 231 244 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L12_07840 1c7db4ef951d276dad9ff4a5791bd6c4 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 27 277 41.416 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A3L12_07840 1c7db4ef951d276dad9ff4a5791bd6c4 279 Gene3D G3DSA:3.40.50.150 88 278 2.3E-58 T 23-10-2018 A3L12_07840 1c7db4ef951d276dad9ff4a5791bd6c4 279 SUPERFAMILY SSF53335 22 277 1.08E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07840 1c7db4ef951d276dad9ff4a5791bd6c4 279 Gene3D G3DSA:3.30.300.110 21 87 3.4E-28 T 23-10-2018 A3L12_07840 1c7db4ef951d276dad9ff4a5791bd6c4 279 Pfam PF02475 Met-10+ like-protein 30 224 1.4E-68 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 SUPERFAMILY SSF53187 5 345 4.34E-69 T 23-10-2018 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 PIRSF PIRSF001123 1 347 1.5E-122 T 23-10-2018 IPR008007 Peptidase M42 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 Gene3D G3DSA:2.40.30.40 68 161 5.2E-137 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 Gene3D G3DSA:3.40.630.10 6 336 5.2E-137 T 23-10-2018 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 SUPERFAMILY SSF101821 68 177 1.18E-29 T 23-10-2018 A3L12_06840 1e6e09bb371065cb952584ac9fd1e4d9 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 7.4E-112 T 23-10-2018 IPR008007 Peptidase M42 A3L12_03020 94b1aac9bb4bc95b5a2fcee6bce4290f 200 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.601 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L12_03020 94b1aac9bb4bc95b5a2fcee6bce4290f 200 SUPERFAMILY SSF111278 7 191 3.14E-59 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_03020 94b1aac9bb4bc95b5a2fcee6bce4290f 200 Pfam PF02676 Methyltransferase TYW3 11 192 5.8E-44 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_03020 94b1aac9bb4bc95b5a2fcee6bce4290f 200 Gene3D G3DSA:3.30.1960.10 2 196 3.0E-65 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_04580 a54a892c09d8c48a6c16bfb0226687f2 276 SMART SM00729 15 214 0.0039 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_04580 a54a892c09d8c48a6c16bfb0226687f2 276 Gene3D G3DSA:3.20.20.70 7 224 2.7E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04580 a54a892c09d8c48a6c16bfb0226687f2 276 SUPERFAMILY SSF102114 14 241 1.96E-26 T 23-10-2018 A3L12_01575 8306266b96de3e179c2494162573ebf3 133 Pfam PF01751 Toprim domain 52 86 8.2E-5 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01575 8306266b96de3e179c2494162573ebf3 133 SMART SM00493 20 90 0.0015 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01575 8306266b96de3e179c2494162573ebf3 133 Gene3D G3DSA:3.40.1360.10 3 117 1.4E-21 T 23-10-2018 A3L12_01575 8306266b96de3e179c2494162573ebf3 133 SUPERFAMILY SSF110455 19 103 1.28E-5 T 23-10-2018 A3L12_01575 8306266b96de3e179c2494162573ebf3 133 Hamap MF_01095 UPF0292 protein . 3 123 31.876 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A3L12_02660 85c7d3c1a1730556982d8f7ae0bc0326 450 Gene3D G3DSA:3.40.50.2000 2 438 8.9E-110 T 23-10-2018 A3L12_02660 85c7d3c1a1730556982d8f7ae0bc0326 450 SUPERFAMILY SSF53756 1 441 7.14E-88 T 23-10-2018 A3L12_02660 85c7d3c1a1730556982d8f7ae0bc0326 450 Pfam PF00534 Glycosyl transferases group 1 255 420 5.7E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L12_02660 85c7d3c1a1730556982d8f7ae0bc0326 450 Pfam PF08323 Starch synthase catalytic domain 2 206 4.7E-34 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A3L12_02660 85c7d3c1a1730556982d8f7ae0bc0326 450 Gene3D G3DSA:3.40.50.2000 220 428 8.9E-110 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 296 2.3E-66 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 1.2E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 Gene3D G3DSA:3.50.50.60 107 431 3.5E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 Gene3D G3DSA:3.50.50.60 2 331 3.5E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 4.1E-16 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.1E-16 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.1E-16 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.1E-16 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 8.3E-24 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 8.3E-24 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 8.3E-24 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 8.3E-24 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 8.3E-24 T 23-10-2018 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 SUPERFAMILY SSF51905 142 307 2.51E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 SUPERFAMILY SSF55424 316 436 1.29E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L12_02365 7bd1ef49dafb205d516399fdb9042683 439 SUPERFAMILY SSF51905 2 191 1.6E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 SUPERFAMILY SSF52540 49 392 6.1E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 Gene3D G3DSA:3.40.50.300 16 237 2.7E-51 T 23-10-2018 A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 Gene3D G3DSA:3.40.50.300 259 421 8.8E-24 T 23-10-2018 A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 Pfam PF00270 DEAD/DEAH box helicase 38 222 6.7E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 SMART SM00490 302 388 2.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 SMART SM00487 33 261 7.6E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 Pfam PF00271 Helicase conserved C-terminal domain 278 384 7.9E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 Pfam PF08494 DEAD/H associated 642 830 8.5E-55 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L12_05200 373eaf5815b165e406e464d2a74f0c7e 864 PIRSF PIRSF037307 8 863 1.5E-283 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L12_04665 25be5408566078b132d9bf61e074040d 751 Pfam PF03176 MMPL family 521 740 1.0E-22 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L12_04665 25be5408566078b132d9bf61e074040d 751 Pfam PF03176 MMPL family 140 403 5.4E-35 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L12_04665 25be5408566078b132d9bf61e074040d 751 SUPERFAMILY SSF82866 554 745 9.94E-38 T 23-10-2018 A3L12_04665 25be5408566078b132d9bf61e074040d 751 SUPERFAMILY SSF82866 145 363 9.16E-44 T 23-10-2018 A3L12_04665 25be5408566078b132d9bf61e074040d 751 Gene3D G3DSA:1.20.1640.10 584 751 8.4E-15 T 23-10-2018 A3L12_04665 25be5408566078b132d9bf61e074040d 751 Gene3D G3DSA:1.20.1640.10 192 376 8.9E-24 T 23-10-2018 A3L12_04665 25be5408566078b132d9bf61e074040d 751 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 12 740 3.1E-217 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 A3L12_01435 cf8b6f3d79f9b4596419275d509b7c05 250 Gene3D G3DSA:1.10.3720.10 4 249 1.4E-66 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01435 cf8b6f3d79f9b4596419275d509b7c05 250 SUPERFAMILY SSF161098 7 241 9.35E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01435 cf8b6f3d79f9b4596419275d509b7c05 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 8.9E-23 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 5.5E-22 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 SMART SM01383 11 85 2.6E-27 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.225 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 SUPERFAMILY SSF50104 94 237 1.26E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 SMART SM01382 91 223 9.5E-60 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 SUPERFAMILY SSF50249 2 92 9.6E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Gene3D G3DSA:4.10.950.10 163 239 6.7E-35 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Gene3D G3DSA:2.30.30.30 85 162 1.2E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Gene3D G3DSA:2.40.50.140 1 81 5.6E-32 T 23-10-2018 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 PIRSF PIRSF002158 1 239 7.8E-73 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00605 20dcde1be414f5425faac8e6e0d5d152 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 222 1.4E-41 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 Gene3D G3DSA:2.40.50.140 310 354 5.2E-21 T 23-10-2018 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 Pfam PF08402 TOBE domain 288 363 1.2E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 Gene3D G3DSA:3.40.50.300 2 243 4.7E-75 T 23-10-2018 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 SUPERFAMILY SSF52540 4 249 2.1E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 SUPERFAMILY SSF50331 242 371 9.72E-27 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 SMART SM00382 28 217 4.5E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 Pfam PF00005 ABC transporter 20 167 6.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_02625 8c733cd79cc52f1c7f79073f170c108e 372 Gene3D G3DSA:2.40.50.100 245 304 1.2E-22 T 23-10-2018 A3L12_02920 33de91675462d251707acec997e5cbd8 314 SUPERFAMILY SSF51735 2 149 2.92E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02920 33de91675462d251707acec997e5cbd8 314 Gene3D G3DSA:3.40.50.720 2 287 1.1E-82 T 23-10-2018 A3L12_02920 33de91675462d251707acec997e5cbd8 314 SUPERFAMILY SSF55347 126 290 1.19E-28 T 23-10-2018 A3L12_02920 33de91675462d251707acec997e5cbd8 314 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 4.9E-28 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L12_02920 33de91675462d251707acec997e5cbd8 314 Gene3D G3DSA:3.30.360.10 122 299 1.1E-82 T 23-10-2018 A3L12_02920 33de91675462d251707acec997e5cbd8 314 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 227 1.3E-5 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 SUPERFAMILY SSF54984 9 91 4.05E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 PIRSF PIRSF006521 3 91 2.3E-32 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.892 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 2.6E-20 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 4.7E-22 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 SMART SM00888 5 91 6.7E-32 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L12_03005 1354c9a397739b2709e16e638714b0fc 91 Gene3D G3DSA:3.30.70.60 1 91 2.5E-35 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A3L12_05835 2cae0c552926b5e54e16dd9233f55168 327 SUPERFAMILY SSF64182 18 306 3.66E-48 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L12_05835 2cae0c552926b5e54e16dd9233f55168 327 Gene3D G3DSA:3.90.1640.10 5 185 5.6E-36 T 23-10-2018 A3L12_05835 2cae0c552926b5e54e16dd9233f55168 327 Pfam PF02272 DHHA1 domain 225 317 5.7E-11 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L12_05835 2cae0c552926b5e54e16dd9233f55168 327 Gene3D G3DSA:3.10.310.40 228 321 1.6E-5 T 23-10-2018 A3L12_05835 2cae0c552926b5e54e16dd9233f55168 327 Pfam PF01368 DHH family 19 159 4.4E-12 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L12_01610 5eb03b04db972ceef7925daf5354b6fe 289 Gene3D G3DSA:3.40.50.1820 43 289 1.3E-43 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_01610 5eb03b04db972ceef7925daf5354b6fe 289 Pfam PF12146 Serine aminopeptidase, S33 67 192 5.2E-14 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L12_01610 5eb03b04db972ceef7925daf5354b6fe 289 SUPERFAMILY SSF53474 6 287 8.11E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_01305 353f095108128608ce696c0f2922e557 168 Pfam PF13247 4Fe-4S dicluster domain 44 134 2.1E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01305 353f095108128608ce696c0f2922e557 168 Gene3D G3DSA:3.30.70.20 30 162 2.5E-39 T 23-10-2018 A3L12_01305 353f095108128608ce696c0f2922e557 168 SUPERFAMILY SSF54862 1 149 9.31E-52 T 23-10-2018 A3L12_01305 353f095108128608ce696c0f2922e557 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_01305 353f095108128608ce696c0f2922e557 168 PRINTS PR00354 7Fe ferredoxin signature 75 92 7.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01305 353f095108128608ce696c0f2922e557 168 PRINTS PR00354 7Fe ferredoxin signature 48 58 7.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01305 353f095108128608ce696c0f2922e557 168 PRINTS PR00354 7Fe ferredoxin signature 58 68 7.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01305 353f095108128608ce696c0f2922e557 168 Pfam PF00037 4Fe-4S binding domain 7 23 1.2E-4 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_02090 5a27c9acda38de47cd812904185f9ecf 200 Gene3D G3DSA:1.10.10.10 2 82 7.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_02090 5a27c9acda38de47cd812904185f9ecf 200 SUPERFAMILY SSF55261 87 197 7.19E-33 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L12_02090 5a27c9acda38de47cd812904185f9ecf 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 1.9E-47 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A3L12_02090 5a27c9acda38de47cd812904185f9ecf 200 Gene3D G3DSA:3.30.1360.30 83 191 1.3E-39 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L12_02090 5a27c9acda38de47cd812904185f9ecf 200 SUPERFAMILY SSF46785 18 75 1.28E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 SUPERFAMILY SSF48239 305 537 6.8E-23 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 SUPERFAMILY SSF48239 68 340 9.81E-25 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 75 101 0.24 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 307 337 0.0065 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 Gene3D G3DSA:1.50.10.20 376 517 1.9E-13 T 23-10-2018 A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 Gene3D G3DSA:1.50.10.20 20 161 5.6E-16 T 23-10-2018 A3L12_03235 5426993c5962835efcdd8f9ee2a5ae9c 727 Gene3D G3DSA:1.50.10.20 274 358 1.2E-6 T 23-10-2018 A3L12_04470 6a5b303377cf18b201034faecd25ec5b 122 Pfam PF03334 Na+/H+ antiporter subunit 11 100 1.3E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_04470 6a5b303377cf18b201034faecd25ec5b 122 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 9.9E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_03765 f2dee43be3d9faa314b6d8825cebc6fc 335 Gene3D G3DSA:3.40.50.150 148 335 2.5E-31 T 23-10-2018 A3L12_03765 f2dee43be3d9faa314b6d8825cebc6fc 335 SUPERFAMILY SSF53335 87 333 1.79E-42 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03765 f2dee43be3d9faa314b6d8825cebc6fc 335 Pfam PF02475 Met-10+ like-protein 87 264 7.5E-33 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L12_03765 f2dee43be3d9faa314b6d8825cebc6fc 335 Gene3D G3DSA:3.30.300.110 62 144 1.9E-11 T 23-10-2018 A3L12_07790 62ff5c44c852889db791ebf96af97aed 247 SUPERFAMILY SSF159713 9 243 2.62E-60 T 23-10-2018 A3L12_07790 62ff5c44c852889db791ebf96af97aed 247 Pfam PF13938 Putative heavy-metal chelation 9 89 7.4E-14 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A3L12_07790 62ff5c44c852889db791ebf96af97aed 247 Gene3D G3DSA:3.40.50.11590 104 215 6.2E-25 T 23-10-2018 A3L12_07790 62ff5c44c852889db791ebf96af97aed 247 Pfam PF04016 Putative heavy-metal chelation 112 242 2.2E-36 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A3L12_07790 62ff5c44c852889db791ebf96af97aed 247 Gene3D G3DSA:3.30.390.100 11 218 6.2E-25 T 23-10-2018 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 SUPERFAMILY SSF47060 66 143 5.89E-25 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 5.7E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 SMART SM01387 70 149 5.8E-26 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.493 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 SMART SM01386 1 60 2.7E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 Gene3D G3DSA:1.10.287.10 83 151 1.1E-31 T 23-10-2018 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 Gene3D G3DSA:1.10.8.1030 36 82 7.1E-21 T 23-10-2018 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 73 128 0.001 T 23-10-2018 A3L12_05550 9b452c8ba7bb663f7c9b48f897342669 151 Pfam PF00312 Ribosomal protein S15 73 148 6.0E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05770 4e235baa8a42171c9a188cc3c20f9940 155 SUPERFAMILY SSF49777 7 154 7.98E-46 T 23-10-2018 IPR036610 PEBP-like superfamily A3L12_05770 4e235baa8a42171c9a188cc3c20f9940 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 152 1.7E-42 T 23-10-2018 IPR005247 YbhB/YbcL A3L12_05770 4e235baa8a42171c9a188cc3c20f9940 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 15 152 5.3E-35 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A3L12_05770 4e235baa8a42171c9a188cc3c20f9940 155 Gene3D G3DSA:3.90.280.10 5 155 2.6E-51 T 23-10-2018 IPR036610 PEBP-like superfamily A3L12_01295 989b5ec9405b7c7887fd4527a96c1a15 125 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 7 18 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_01295 989b5ec9405b7c7887fd4527a96c1a15 125 Gene3D G3DSA:3.30.70.20 45 79 3.5E-5 T 23-10-2018 A3L12_01295 989b5ec9405b7c7887fd4527a96c1a15 125 Pfam PF12838 4Fe-4S dicluster domain 7 54 5.3E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01295 989b5ec9405b7c7887fd4527a96c1a15 125 SUPERFAMILY SSF54862 5 60 4.92E-15 T 23-10-2018 A3L12_01295 989b5ec9405b7c7887fd4527a96c1a15 125 Gene3D G3DSA:3.30.70.20 1 44 8.6E-9 T 23-10-2018 A3L12_01780 79a75241c43302209f4e0d2640960641 65 Gene3D G3DSA:2.20.25.100 11 65 1.6E-24 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A3L12_01780 79a75241c43302209f4e0d2640960641 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01780 79a75241c43302209f4e0d2640960641 65 Pfam PF01667 Ribosomal protein S27 11 64 9.1E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01780 79a75241c43302209f4e0d2640960641 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.314 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01780 79a75241c43302209f4e0d2640960641 65 SUPERFAMILY SSF57829 11 65 4.21E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_05905 402897a40b615638c1bc925fab635588 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 3.6E-46 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L12_05905 402897a40b615638c1bc925fab635588 219 Gene3D G3DSA:3.40.1280.10 1 219 8.6E-73 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L12_05905 402897a40b615638c1bc925fab635588 219 SUPERFAMILY SSF75217 1 216 5.36E-59 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L12_05905 402897a40b615638c1bc925fab635588 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 39.45 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 44.657 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 SUPERFAMILY SSF52317 1 186 5.5E-55 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 2.5E-80 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.1E-12 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 5.1E-12 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 5.1E-12 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 5.1E-12 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 9.8E-6 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 9.8E-6 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 8.2E-10 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 8.2E-10 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 8.2E-10 T 23-10-2018 A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 1.1E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L12_03180 ca9e37299860bb6361bdbb419b3e8036 188 Gene3D G3DSA:3.40.50.880 1 187 5.4E-62 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 Hamap MF_01168 N-glycosylase/DNA lyase. 18 254 40.324 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 Gene3D G3DSA:1.10.340.30 39 185 2.4E-84 T 23-10-2018 A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 Pfam PF09171 N-glycosylase/DNA lyase 21 239 1.1E-83 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 SUPERFAMILY SSF48150 14 246 1.88E-82 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 Gene3D G3DSA:1.10.1670.10 19 244 2.4E-84 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L12_06100 ee92ca596d390eb4fe9ea5e5c29361a3 260 PIRSF PIRSF008955 10 260 1.5E-101 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L12_01010 a02ef7a03a6718372edc8b659d8f07ef 649 Pfam PF05670 Domain of unknown function (DUF814) 454 551 2.5E-24 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A3L12_01010 a02ef7a03a6718372edc8b659d8f07ef 649 Gene3D G3DSA:2.30.310.10 5 150 6.8E-32 T 23-10-2018 A3L12_01010 a02ef7a03a6718372edc8b659d8f07ef 649 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 432 5.9E-81 T 23-10-2018 A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 SUPERFAMILY SSF53187 225 415 3.77E-30 T 23-10-2018 A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 Gene3D G3DSA:3.40.630.10 28 403 3.6E-56 T 23-10-2018 A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 Pfam PF02225 PA domain 117 186 8.6E-8 T 23-10-2018 IPR003137 PA domain A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 Pfam PF04389 Peptidase family M28 228 409 2.9E-19 T 23-10-2018 IPR007484 Peptidase M28 A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 Gene3D G3DSA:3.50.30.30 71 207 3.6E-56 T 23-10-2018 A3L12_03340 37d2479045cf9e84722bb39eae42900a 559 SUPERFAMILY SSF52025 92 198 1.83E-6 T 23-10-2018 A3L12_05120 d9f92db0bd0e322a7e9707f69b30cc6f 250 Pfam PF00994 Probable molybdopterin binding domain 4 176 6.2E-34 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_05120 d9f92db0bd0e322a7e9707f69b30cc6f 250 SMART SM00852 4 179 6.9E-40 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_05120 d9f92db0bd0e322a7e9707f69b30cc6f 250 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 38.779 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea A3L12_05120 d9f92db0bd0e322a7e9707f69b30cc6f 250 Gene3D G3DSA:3.40.980.10 2 179 4.6E-53 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_05120 d9f92db0bd0e322a7e9707f69b30cc6f 250 SUPERFAMILY SSF53218 1 205 2.88E-38 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 Pfam PF02384 N-6 DNA Methylase 159 472 9.9E-107 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 281 287 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 199 4.6E-21 T 23-10-2018 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 278 290 4.6E-21 T 23-10-2018 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 206 220 4.6E-21 T 23-10-2018 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 318 342 4.6E-21 T 23-10-2018 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 SUPERFAMILY SSF53335 4 516 2.05E-129 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 Gene3D G3DSA:3.40.50.150 160 460 8.9E-97 T 23-10-2018 A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 Gene3D G3DSA:1.20.1260.30 1 151 6.8E-36 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A3L12_01350 f5c0f34b709b53fe7f463b5d29604a13 517 Pfam PF12161 HsdM N-terminal domain 6 147 5.3E-22 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A3L12_02125 62fd1e61f9172e30a880738f0da9dd76 392 SUPERFAMILY SSF53383 10 390 1.46E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_02125 62fd1e61f9172e30a880738f0da9dd76 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L12_02125 62fd1e61f9172e30a880738f0da9dd76 392 Gene3D G3DSA:3.90.1150.10 33 384 6.8E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_02125 62fd1e61f9172e30a880738f0da9dd76 392 Gene3D G3DSA:3.40.640.10 65 284 6.8E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_02125 62fd1e61f9172e30a880738f0da9dd76 392 Pfam PF00155 Aminotransferase class I and II 33 384 7.6E-76 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 39 71 2.3E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 Gene3D G3DSA:2.160.10.10 4 155 4.2E-46 T 23-10-2018 A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 9 35 8.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 140 3.0E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 SUPERFAMILY SSF51161 7 158 6.1E-45 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L12_02940 fe2e680822deeb5e796d2129161656fb 204 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 114 142 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A3L12_05025 8fa2f8c0176723b086003901bc9fe082 89 Gene3D G3DSA:1.10.10.10 1 53 1.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05025 8fa2f8c0176723b086003901bc9fe082 89 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 50 1.6E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_05025 8fa2f8c0176723b086003901bc9fe082 89 SUPERFAMILY SSF46785 4 63 2.67E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 Gene3D G3DSA:1.10.569.10 281 472 3.4E-12 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 1.5E-39 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 573 1.9E-16 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 SMART SM00790 1 226 5.1E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 Gene3D G3DSA:3.60.9.10 1 227 1.0E-23 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 SUPERFAMILY SSF48310 241 650 9.42E-64 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_04140 c0c6da8cc49352eb25fa0ee5a87ebebf 652 SUPERFAMILY SSF56228 3 228 4.97E-43 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 Gene3D G3DSA:3.50.50.60 16 138 1.9E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 SUPERFAMILY SSF51971 17 284 2.0E-51 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 331 2.0E-34 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 2.4E-21 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 2.4E-21 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.4E-21 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 2.4E-21 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.4E-21 T 23-10-2018 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 312 330 2.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 2.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 2.1E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L12_01300 8f87dfd29253fde25c7ac4ff99e4095a 351 Gene3D G3DSA:3.50.50.60 139 283 4.3E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.6E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.6E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 SUPERFAMILY SSF51735 8 258 1.13E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 3.4E-49 T 23-10-2018 A3L12_07245 8062f0c68cadc5557495a0f7bd0f5562 263 Gene3D G3DSA:3.40.50.720 1 262 3.1E-63 T 23-10-2018 A3L12_04560 85e227e8f153baff8c2fa7ac3218d542 199 Pfam PF07155 ECF-type riboflavin transporter, S component 40 190 1.4E-39 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A3L12_04560 85e227e8f153baff8c2fa7ac3218d542 199 Gene3D G3DSA:1.10.1760.20 37 195 4.4E-48 T 23-10-2018 A3L12_05990 e0d7f522504e39fe52c962e925a411b2 602 Pfam PF05124 S-layer like family, C-terminal region 378 599 3.4E-31 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L12_05990 e0d7f522504e39fe52c962e925a411b2 602 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 599 1.2E-66 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L12_05990 e0d7f522504e39fe52c962e925a411b2 602 Pfam PF05123 S-layer like family, N-terminal region 4 308 9.9E-46 T 23-10-2018 IPR022650 S-layer protein, N-terminal A3L12_05220 f67e4610f85afd37c45ace7ff621764b 204 Pfam PF02581 Thiamine monophosphate synthase 9 185 1.8E-63 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_05220 f67e4610f85afd37c45ace7ff621764b 204 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 203 28.228 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_05220 f67e4610f85afd37c45ace7ff621764b 204 Gene3D G3DSA:3.20.20.70 2 203 3.3E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_05220 f67e4610f85afd37c45ace7ff621764b 204 SUPERFAMILY SSF51391 6 200 2.75E-67 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_05220 f67e4610f85afd37c45ace7ff621764b 204 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 197 4.2E-65 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 8 373 4.3E-99 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 Gene3D G3DSA:1.20.1250.20 5 187 3.7E-23 T 23-10-2018 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 Gene3D G3DSA:1.20.1250.20 207 401 4.3E-13 T 23-10-2018 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 Pfam PF07690 Major Facilitator Superfamily 12 363 1.4E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 SUPERFAMILY SSF103473 6 400 1.83E-42 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 47 65 1.8E-6 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 163 180 1.8E-6 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 136 157 1.8E-6 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L12_05140 636ab706ecba368f33c2c9dcef85b908 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 73 91 1.8E-6 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L12_01675 80df62623e5b077235b4a512187342ad 197 Gene3D G3DSA:3.90.550.10 4 191 2.1E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01675 80df62623e5b077235b4a512187342ad 197 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 186 20.336 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A3L12_01675 80df62623e5b077235b4a512187342ad 197 SUPERFAMILY SSF53448 1 183 3.83E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01675 80df62623e5b077235b4a512187342ad 197 Pfam PF12804 MobA-like NTP transferase domain 3 146 5.9E-29 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 182.881 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 7.1E-174 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 Gene3D G3DSA:3.40.50.720 3 331 1.1E-145 T 23-10-2018 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 148 296 2.5E-27 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 115 2.4E-13 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 Gene3D G3DSA:3.30.360.10 140 301 1.1E-145 T 23-10-2018 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 SUPERFAMILY SSF51735 3 158 2.06E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 SUPERFAMILY SSF55347 140 301 1.78E-49 T 23-10-2018 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 PIRSF PIRSF000149 1 318 2.0E-81 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_05115 6240abad1e5b3ceb13e95eeeb72b2961 334 SMART SM00846 3 141 3.6E-19 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_03485 cf64828ddedc257710c20ce8038e304d 265 Gene3D G3DSA:2.40.50.140 9 138 3.1E-13 T 23-10-2018 A3L12_03485 cf64828ddedc257710c20ce8038e304d 265 SUPERFAMILY SSF50249 34 130 1.2E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_03485 cf64828ddedc257710c20ce8038e304d 265 Pfam PF01336 OB-fold nucleic acid binding domain 55 114 1.0E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L12_06000 bda021db330451ca857ecd9218b72dc1 581 Pfam PF04055 Radical SAM superfamily 204 403 6.5E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_06000 bda021db330451ca857ecd9218b72dc1 581 SMART SM00729 200 450 1.3E-31 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_06000 bda021db330451ca857ecd9218b72dc1 581 Gene3D G3DSA:3.80.30.20 200 457 1.4E-24 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L12_06000 bda021db330451ca857ecd9218b72dc1 581 SUPERFAMILY SSF47781 523 570 6.67E-6 T 23-10-2018 IPR010994 RuvA domain 2-like A3L12_06000 bda021db330451ca857ecd9218b72dc1 581 SUPERFAMILY SSF102114 198 442 8.5E-28 T 23-10-2018 A3L12_02610 af782f3421fc637d7341b3470c0c7e2d 271 SUPERFAMILY SSF56281 3 252 1.04E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_02610 af782f3421fc637d7341b3470c0c7e2d 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 7.3E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_02610 af782f3421fc637d7341b3470c0c7e2d 271 Gene3D G3DSA:3.60.15.10 1 251 1.0E-26 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_03910 5e42becd6a7e2f487f3b7c97fb07ab7f 1057 SUPERFAMILY SSF54001 189 314 1.96E-23 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L12_03910 5e42becd6a7e2f487f3b7c97fb07ab7f 1057 Pfam PF01841 Transglutaminase-like superfamily 200 310 8.3E-23 T 23-10-2018 IPR002931 Transglutaminase-like A3L12_03910 5e42becd6a7e2f487f3b7c97fb07ab7f 1057 Gene3D G3DSA:3.10.620.30 174 324 2.0E-17 T 23-10-2018 A3L12_03910 5e42becd6a7e2f487f3b7c97fb07ab7f 1057 Pfam PF13559 Domain of unknown function (DUF4129) 991 1040 2.2E-5 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L12_03910 5e42becd6a7e2f487f3b7c97fb07ab7f 1057 SMART SM00460 244 312 5.8E-18 T 23-10-2018 IPR002931 Transglutaminase-like A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 SUPERFAMILY SSF52540 5 170 6.94E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 Pfam PF02421 Ferrous iron transport protein B 4 159 1.9E-63 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 Gene3D G3DSA:3.40.50.300 1 169 7.0E-48 T 23-10-2018 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 3.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 Pfam PF07670 Nucleoside recognition 353 447 1.9E-13 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 Pfam PF07670 Nucleoside recognition 514 628 1.6E-26 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 Pfam PF07664 Ferrous iron transport protein B C terminus 458 509 2.5E-19 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A3L12_05030 27952ed0f3c2e2e9a2d98e70e7409eea 658 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 625 5.9E-187 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A3L12_00585 3f97f3469693205cc99dfc1fd9564a32 255 SUPERFAMILY SSF50249 91 156 9.77E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_00585 3f97f3469693205cc99dfc1fd9564a32 255 Gene3D G3DSA:3.40.1280.10 5 251 8.2E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L12_00585 3f97f3469693205cc99dfc1fd9564a32 255 Pfam PF02598 Putative RNA methyltransferase 5 248 4.4E-49 T 23-10-2018 IPR003750 Putative RNA methyltransferase A3L12_00585 3f97f3469693205cc99dfc1fd9564a32 255 SUPERFAMILY SSF75217 4 253 2.41E-46 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L12_00585 3f97f3469693205cc99dfc1fd9564a32 255 Gene3D G3DSA:2.40.50.140 91 156 8.2E-75 T 23-10-2018 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 Gene3D G3DSA:2.40.30.30 86 211 6.4E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.525 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 Gene3D G3DSA:1.10.10.10 1 83 7.0E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 Pfam PF01982 Domain of unknown function DUF120 92 209 3.9E-37 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 SUPERFAMILY SSF82114 88 209 3.24E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 SMART SM00419 14 66 0.0065 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 Pfam PF12802 MarR family 5 53 8.9E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L12_05430 ffd664464eb75db83fbe3ce884dad7f9 211 SUPERFAMILY SSF46785 5 82 1.09E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 Pfam PF00375 Sodium:dicarboxylate symporter family 16 412 1.4E-124 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 228 247 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 2.0E-37 T 23-10-2018 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 Gene3D G3DSA:1.10.3860.10 1 424 7.6E-163 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 41 56 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A3L12_07330 fbebf77881b43d9c243476f25d4e9638 424 SUPERFAMILY SSF118215 16 414 3.66E-120 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Pfam PF12838 4Fe-4S dicluster domain 591 637 2.7E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 562 2.1E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Gene3D G3DSA:3.40.50.970 390 568 6.8E-21 T 23-10-2018 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 209 1.4E-14 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 638 4.4E-267 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 SUPERFAMILY SSF52518 380 601 1.25E-32 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 SUPERFAMILY SSF54862 583 642 8.95E-13 T 23-10-2018 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 623 634 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 SUPERFAMILY SSF52518 14 249 1.56E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Gene3D G3DSA:3.40.50.970 5 196 1.9E-54 T 23-10-2018 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 PIRSF PIRSF006439 5 645 1.2E-260 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 SUPERFAMILY SSF52922 249 355 8.01E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_02210 c5be7fdaab40f2ab90ebd0c125564366 646 Gene3D G3DSA:3.30.70.20 577 640 5.6E-11 T 23-10-2018 A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 SUPERFAMILY SSF55326 6 147 1.38E-20 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 50 143 3.3E-12 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 PIRSF PIRSF005644 1 328 1.6E-63 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 304 6.4E-17 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 SUPERFAMILY SSF56042 152 313 3.59E-26 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 Gene3D G3DSA:3.30.1330.10 4 146 6.6E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_05045 043b521ede63e2a7b527c2d902cb855b 337 Gene3D G3DSA:3.90.650.10 152 326 9.4E-30 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_03385 ad3975f08c4431148845485557d6ae2c 99 Pfam PF11537 Protein of unknown function (DUF3227) 7 90 3.4E-21 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A3L12_03385 ad3975f08c4431148845485557d6ae2c 99 Gene3D G3DSA:1.10.1200.200 5 98 2.9E-24 T 23-10-2018 A3L12_05360 07bac69696fe8f65f783ed0a8da8b62d 274 Gene3D G3DSA:1.10.10.10 200 272 3.9E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05360 07bac69696fe8f65f783ed0a8da8b62d 274 SUPERFAMILY SSF46785 205 265 1.55E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_05360 07bac69696fe8f65f783ed0a8da8b62d 274 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 207 265 3.6E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.812 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 13 79 5.0E-23 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 SUPERFAMILY SSF55287 7 80 3.27E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 1.4E-31 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_01705 b211f9c89cb8856757605ab2c554c568 82 Gene3D G3DSA:3.90.940.20 1 82 7.6E-36 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 412 482 1.5E-15 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 SUPERFAMILY SSF55681 11 277 1.15E-75 T 23-10-2018 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Hamap MF_01571 Proline--tRNA ligase [proS]. 6 482 40.979 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 482 1.6E-176 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 SMART SM00946 411 482 9.7E-25 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Pfam PF03129 Anticodon binding domain 290 384 8.8E-22 T 23-10-2018 IPR004154 Anticodon-binding A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Gene3D G3DSA:3.30.110.30 405 481 9.2E-18 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Gene3D G3DSA:3.30.930.10 12 283 2.4E-84 T 23-10-2018 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Gene3D G3DSA:3.40.50.800 284 402 5.4E-37 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 272 3.0E-23 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 4.6E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.6E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.6E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 4.6E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 SUPERFAMILY SSF52954 279 403 7.1E-37 T 23-10-2018 A3L12_05385 a5b46daf10cb4f82d13368f36f9fb110 482 SUPERFAMILY SSF64586 406 482 2.16E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_02445 eb284b066bf0e6c375ad848e6c31e677 658 Gene3D G3DSA:3.30.70.2170 18 310 6.3E-18 T 23-10-2018 A3L12_02445 eb284b066bf0e6c375ad848e6c31e677 658 Pfam PF01496 V-type ATPase 116kDa subunit family 554 646 8.8E-13 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02445 eb284b066bf0e6c375ad848e6c31e677 658 Pfam PF01496 V-type ATPase 116kDa subunit family 196 441 3.0E-22 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02445 eb284b066bf0e6c375ad848e6c31e677 658 Gene3D G3DSA:1.20.1460.20 47 290 6.3E-18 T 23-10-2018 A3L12_02445 eb284b066bf0e6c375ad848e6c31e677 658 Gene3D G3DSA:3.30.70.2750 149 224 6.3E-18 T 23-10-2018 A3L12_00855 4bc0d66dd16fa37d3f40ff3ee17e0ac2 267 Pfam PF01048 Phosphorylase superfamily 3 246 8.0E-55 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L12_00855 4bc0d66dd16fa37d3f40ff3ee17e0ac2 267 SUPERFAMILY SSF53167 1 264 8.25E-96 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L12_00855 4bc0d66dd16fa37d3f40ff3ee17e0ac2 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 4.6E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L12_00855 4bc0d66dd16fa37d3f40ff3ee17e0ac2 267 Gene3D G3DSA:3.40.50.1580 1 266 8.1E-100 T 23-10-2018 A3L12_00855 4bc0d66dd16fa37d3f40ff3ee17e0ac2 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.437 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L12_02300 784d175e7cfc858c9e835f53321e09b6 136 Gene3D G3DSA:3.30.300.20 4 134 2.8E-35 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_02300 784d175e7cfc858c9e835f53321e09b6 136 Pfam PF02566 OsmC-like protein 32 121 8.7E-16 T 23-10-2018 IPR003718 OsmC/Ohr family A3L12_02300 784d175e7cfc858c9e835f53321e09b6 136 SUPERFAMILY SSF82784 8 133 1.01E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 192 383 39.329 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 Gene3D G3DSA:3.90.870.10 2 195 8.8E-45 T 23-10-2018 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 SUPERFAMILY SSF55821 2 185 9.39E-46 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 184 5.5E-44 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 SUPERFAMILY SSF142695 193 359 8.76E-59 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 Pfam PF00925 GTP cyclohydrolase II 197 357 4.7E-66 T 23-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 197 381 2.9E-73 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 Gene3D G3DSA:3.40.50.10990 196 360 1.1E-67 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A3L12_03060 29fc90a64109a35caed3657ae8dfb35c 389 PIRSF PIRSF001259 1 386 2.1E-126 T 23-10-2018 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 Gene3D G3DSA:2.30.30.30 88 152 2.2E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 SMART SM00738 3 87 3.0E-19 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 1.9E-23 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.482 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 SUPERFAMILY SSF50104 55 147 8.28E-18 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 6.8E-53 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 Gene3D G3DSA:3.30.70.940 3 87 1.5E-32 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 SMART SM00739 92 119 1.2E-6 T 23-10-2018 IPR005824 KOW A3L12_02010 761990d16d7c922ea1e2eb9d6f1c042a 152 Pfam PF00467 KOW motif 95 126 2.3E-8 T 23-10-2018 IPR005824 KOW A3L12_01085 9565ec0beee1356b87eb7af2201dbf5e 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 425 4.0E-73 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_01085 9565ec0beee1356b87eb7af2201dbf5e 465 Pfam PF01554 MatE 283 419 4.9E-24 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_01085 9565ec0beee1356b87eb7af2201dbf5e 465 Pfam PF01554 MatE 28 188 3.5E-32 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_01085 9565ec0beee1356b87eb7af2201dbf5e 465 PIRSF PIRSF006603 2 464 2.6E-139 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Pfam PF03464 eRF1 domain 2 140 272 1.7E-48 T 23-10-2018 IPR005141 eRF1 domain 2 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Pfam PF03463 eRF1 domain 1 20 133 1.5E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Gene3D G3DSA:3.30.1330.30 274 415 3.0E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 SUPERFAMILY SSF55481 3 135 3.14E-48 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Gene3D G3DSA:3.30.960.10 1 135 1.7E-53 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Pfam PF03465 eRF1 domain 3 276 414 1.0E-34 T 23-10-2018 IPR005142 eRF1 domain 3 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 SMART SM01194 1 135 1.6E-33 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.114 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 SUPERFAMILY SSF55315 272 414 1.53E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 Gene3D G3DSA:3.30.420.60 137 271 6.1E-54 T 23-10-2018 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 413 7.3E-179 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05610 31b3361c21b07e17c1de396ce023fd82 415 SUPERFAMILY SSF53137 138 270 1.4E-43 T 23-10-2018 A3L12_00235 ced2d6b2df3e6810b0132f97d925dd75 193 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 191 1.9E-44 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L12_00235 ced2d6b2df3e6810b0132f97d925dd75 193 Gene3D G3DSA:3.40.50.11570 1 193 4.7E-37 T 23-10-2018 A3L12_07505 6f66053cda3b48dee4122946d16520be 357 Pfam PF01032 FecCD transport family 33 352 7.5E-94 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L12_07505 6f66053cda3b48dee4122946d16520be 357 Gene3D G3DSA:1.10.3470.10 21 356 1.8E-100 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L12_07505 6f66053cda3b48dee4122946d16520be 357 SUPERFAMILY SSF81345 19 352 9.94E-82 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L12_05730 54613a9429a1bbb47d865feea44a8e51 196 Gene3D G3DSA:1.20.120.330 32 170 9.6E-7 T 23-10-2018 A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 SUPERFAMILY SSF109755 10 103 2.88E-18 T 23-10-2018 A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 Pfam PF01895 PhoU domain 19 101 2.0E-11 T 23-10-2018 IPR026022 PhoU domain A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 Gene3D G3DSA:1.20.58.220 1 117 2.3E-27 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 Gene3D G3DSA:3.30.70.1450 118 205 1.1E-25 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 Pfam PF02080 TrkA-C domain 124 192 1.7E-12 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L12_07145 a2c30a1b94796a9e048407d7e44d5f24 205 SUPERFAMILY SSF116726 110 192 1.57E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_06910 1bf0790329941ce4cb1303ffff20a531 143 Gene3D G3DSA:3.10.330.10 1 77 2.7E-27 T 23-10-2018 A3L12_06910 1bf0790329941ce4cb1303ffff20a531 143 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 13 73 9.9E-6 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06910 1bf0790329941ce4cb1303ffff20a531 143 SMART SM01072 12 74 1.8E-5 T 23-10-2018 IPR004201 CDC48, domain 2 A3L12_06910 1bf0790329941ce4cb1303ffff20a531 143 SUPERFAMILY SSF54585 2 75 1.7E-11 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L12_06910 1bf0790329941ce4cb1303ffff20a531 143 Gene3D G3DSA:2.40.10.360 81 143 6.4E-15 T 23-10-2018 A3L12_01810 61802c866507869dcca59604b266e65c 460 SUPERFAMILY SSF53448 1 267 1.23E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01810 61802c866507869dcca59604b266e65c 460 SUPERFAMILY SSF51182 185 459 1.19E-64 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L12_01810 61802c866507869dcca59604b266e65c 460 Pfam PF00483 Nucleotidyl transferase 2 271 5.4E-60 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L12_01810 61802c866507869dcca59604b266e65c 460 Gene3D G3DSA:3.90.550.10 1 341 5.3E-111 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01810 61802c866507869dcca59604b266e65c 460 Pfam PF01050 Mannose-6-phosphate isomerase 305 455 3.8E-66 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L12_01810 61802c866507869dcca59604b266e65c 460 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 458 7.9E-156 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L12_01810 61802c866507869dcca59604b266e65c 460 Gene3D G3DSA:2.60.120.10 345 447 6.0E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L12_07510 0946801ef66722ccdcee8498464e4a5d 249 SUPERFAMILY SSF52540 3 224 1.2E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07510 0946801ef66722ccdcee8498464e4a5d 249 Gene3D G3DSA:3.40.50.300 3 244 1.4E-66 T 23-10-2018 A3L12_07510 0946801ef66722ccdcee8498464e4a5d 249 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_07510 0946801ef66722ccdcee8498464e4a5d 249 Pfam PF00005 ABC transporter 19 164 1.4E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07510 0946801ef66722ccdcee8498464e4a5d 249 SMART SM00382 28 212 2.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_05875 d0eda7e3750f1fac452f4f4323b28ad5 171 Pfam PF06195 Protein of unknown function (DUF996) 23 148 1.6E-22 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 Gene3D G3DSA:3.40.50.300 1 183 7.5E-38 T 23-10-2018 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 178 1.2E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 3.2E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 3.2E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 7.2E-23 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_01450 970b8107bbe5210ddefa622f6d54d720 185 SUPERFAMILY SSF52540 2 182 2.38E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 SMART SM00987 31 185 5.9E-36 T 23-10-2018 A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 Gene3D G3DSA:3.40.470.10 5 191 4.1E-69 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 SMART SM00986 31 185 5.9E-36 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 Pfam PF03167 Uracil DNA glycosylase superfamily 32 180 2.0E-44 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 3.2E-76 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A3L12_04320 37d4d31bd4c6ab6c429d0261eb65dbf9 195 SUPERFAMILY SSF52141 6 191 5.56E-60 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 Pfam PF01884 PcrB family 17 239 5.0E-64 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 241 6.4E-78 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 4.5E-81 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 SUPERFAMILY SSF51395 20 239 2.31E-46 T 23-10-2018 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 247 35.302 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L12_06710 138ddfdd26b5e4457914f90dd7db844e 253 Gene3D G3DSA:3.20.20.390 5 252 4.8E-97 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Gene3D G3DSA:2.40.240.10 418 517 3.0E-44 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 SUPERFAMILY SSF50715 409 561 2.98E-33 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 4 572 2.0E-209 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Gene3D G3DSA:3.40.50.620 93 407 7.3E-121 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 SUPERFAMILY SSF52374 99 415 1.9E-90 T 23-10-2018 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 403 7.0E-85 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Gene3D G3DSA:2.40.240.100 409 571 3.0E-44 T 23-10-2018 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 559 1.5E-31 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_01585 f238b8680c6e87bf042b2871533108bf 572 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 570 39.755 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L12_07265 cc78c9cc2ccc84eb2e9cef4dca7f8d2f 191 SUPERFAMILY SSF53146 1 112 4.45E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_07265 cc78c9cc2ccc84eb2e9cef4dca7f8d2f 191 Gene3D G3DSA:3.30.420.130 1 116 6.4E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_07265 cc78c9cc2ccc84eb2e9cef4dca7f8d2f 191 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 106 8.0E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L12_02945 e7ba09134032083adf0ad48348d0a60b 323 SUPERFAMILY SSF53448 2 266 1.5E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02945 e7ba09134032083adf0ad48348d0a60b 323 Pfam PF13632 Glycosyl transferase family group 2 168 278 6.5E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_02945 e7ba09134032083adf0ad48348d0a60b 323 Pfam PF00535 Glycosyl transferase family 2 6 113 2.3E-22 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_02945 e7ba09134032083adf0ad48348d0a60b 323 Gene3D G3DSA:3.90.550.10 1 221 3.1E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_04770 3ef76a16a4993f710800b4f89e9ee82f 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 88 3.0E-27 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L12_04770 3ef76a16a4993f710800b4f89e9ee82f 126 Pfam PF04322 Protein of unknown function (DUF473) 1 109 1.3E-33 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 36.832 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 Gene3D G3DSA:3.30.310.10 16 97 1.5E-31 T 23-10-2018 IPR012295 TBP domain superfamily A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 SUPERFAMILY SSF55945 96 182 2.2E-29 T 23-10-2018 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 9.8E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 7.0E-27 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 1.4E-27 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 SUPERFAMILY SSF55945 5 95 1.22E-28 T 23-10-2018 A3L12_02220 7cbedfdf3bc9db506abffa1a2f3991e9 192 Gene3D G3DSA:3.30.310.10 98 182 2.4E-34 T 23-10-2018 IPR012295 TBP domain superfamily A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.2E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.2E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.2E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.2E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 1.4E-86 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 3.0E-32 T 23-10-2018 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 SUPERFAMILY SSF56784 1 225 1.44E-48 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 Gene3D G3DSA:3.40.50.1000 3 219 1.2E-84 T 23-10-2018 IPR023214 HAD superfamily A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 4.9E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 93 195 3.9E-13 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 Gene3D G3DSA:1.10.150.520 16 94 1.2E-84 T 23-10-2018 A3L12_07655 96f0f119308def3fd1a4b3627077922f 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 94 193 3.2E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 Gene3D G3DSA:3.40.1190.20 210 325 1.3E-24 T 23-10-2018 IPR029056 Ribokinase-like A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 Gene3D G3DSA:3.40.50.10260 8 205 1.1E-43 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 Pfam PF03853 YjeF-related protein N-terminus 22 182 5.2E-34 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.698 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 SUPERFAMILY SSF53613 213 325 1.47E-16 T 23-10-2018 IPR029056 Ribokinase-like A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 1.3E-43 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 Pfam PF01256 Carbohydrate kinase 227 319 1.3E-12 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L12_00005 c534b272cebc264f9dedd324a0f09f12 325 SUPERFAMILY SSF64153 4 225 4.84E-49 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L12_03275 38f61f795289612a711e51f1c59f7b5e 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.184 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L12_03275 38f61f795289612a711e51f1c59f7b5e 178 SUPERFAMILY SSF50324 1 176 1.15E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L12_03275 38f61f795289612a711e51f1c59f7b5e 178 Pfam PF00719 Inorganic pyrophosphatase 20 170 1.0E-56 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L12_03275 38f61f795289612a711e51f1c59f7b5e 178 Gene3D G3DSA:3.90.80.10 1 178 7.9E-73 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L12_03275 38f61f795289612a711e51f1c59f7b5e 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L12_02290 230e7e5736342f62dd1079c15264d824 281 SUPERFAMILY SSF52317 23 241 3.54E-31 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02290 230e7e5736342f62dd1079c15264d824 281 Pfam PF07722 Peptidase C26 20 219 3.2E-49 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A3L12_02290 230e7e5736342f62dd1079c15264d824 281 Gene3D G3DSA:3.40.50.880 1 247 9.7E-65 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02235 347bbb4ce505a8565fa599483db829f0 158 SUPERFAMILY SSF55729 1 154 9.12E-27 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_02235 347bbb4ce505a8565fa599483db829f0 158 Gene3D G3DSA:3.40.630.30 1 158 5.6E-45 T 23-10-2018 A3L12_02235 347bbb4ce505a8565fa599483db829f0 158 Pfam PF00583 Acetyltransferase (GNAT) family 38 141 1.8E-19 T 23-10-2018 IPR000182 GNAT domain A3L12_00510 ea66bc8833148dfac5ac36e5b4c82a97 522 SUPERFAMILY SSF52096 256 522 1.36E-92 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L12_00510 ea66bc8833148dfac5ac36e5b4c82a97 522 Gene3D G3DSA:3.90.226.10 1 259 3.7E-95 T 23-10-2018 A3L12_00510 ea66bc8833148dfac5ac36e5b4c82a97 522 SUPERFAMILY SSF52096 3 257 3.95E-77 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L12_00510 ea66bc8833148dfac5ac36e5b4c82a97 522 Pfam PF01039 Carboxyl transferase domain 28 519 1.6E-202 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A3L12_00510 ea66bc8833148dfac5ac36e5b4c82a97 522 Gene3D G3DSA:3.90.226.10 261 522 5.1E-96 T 23-10-2018 A3L12_07030 5617739c49dd1bdf7cdba2e30a955dae 173 Gene3D G3DSA:3.40.50.1010 26 167 2.9E-12 T 23-10-2018 A3L12_07030 5617739c49dd1bdf7cdba2e30a955dae 173 Pfam PF01936 NYN domain 34 164 4.8E-21 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L12_07030 5617739c49dd1bdf7cdba2e30a955dae 173 SUPERFAMILY SSF53822 76 150 7.07E-6 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L12_07030 5617739c49dd1bdf7cdba2e30a955dae 173 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 21 166 1.3E-64 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L12_07030 5617739c49dd1bdf7cdba2e30a955dae 173 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 106 2.0E-30 T 23-10-2018 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 SUPERFAMILY SSF51735 6 135 3.02E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 Gene3D G3DSA:3.40.50.720 4 134 5.4E-41 T 23-10-2018 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 SUPERFAMILY SSF52210 136 298 3.66E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 SUPERFAMILY SSF52210 306 464 8.24E-34 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 SMART SM00881 9 107 1.3E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 160 297 3.7E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 Pfam PF13380 CoA binding domain 13 139 4.5E-20 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 Gene3D G3DSA:3.40.50.261 302 467 1.5E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_00030 28dae087b365f9dcab7c20d8a1e7a242 470 Gene3D G3DSA:3.40.50.261 136 300 1.3E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L12_08065 2d49997c27f2ce170a5c6c6a1299e9bd 333 SUPERFAMILY SSF52540 18 136 7.51E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_08065 2d49997c27f2ce170a5c6c6a1299e9bd 333 Gene3D G3DSA:3.40.50.300 74 184 8.1E-8 T 23-10-2018 A3L12_01860 6ac09feee429f04defc08f9c41979408 319 Gene3D G3DSA:1.25.40.10 17 236 8.2E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_01860 6ac09feee429f04defc08f9c41979408 319 SUPERFAMILY SSF48452 76 190 4.81E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_01860 6ac09feee429f04defc08f9c41979408 319 Pfam PF13424 Tetratricopeptide repeat 86 152 4.7E-8 T 23-10-2018 A3L12_01860 6ac09feee429f04defc08f9c41979408 319 SMART SM00028 81 114 15.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_01860 6ac09feee429f04defc08f9c41979408 319 SMART SM00028 121 154 0.055 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_06445 0053684ec63ebde6f8617cc430308feb 84 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 84 16.132 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L12_06445 0053684ec63ebde6f8617cc430308feb 84 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 77 4.2E-14 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L12_06445 0053684ec63ebde6f8617cc430308feb 84 SUPERFAMILY SSF143430 1 77 2.09E-23 T 23-10-2018 A3L12_06445 0053684ec63ebde6f8617cc430308feb 84 Gene3D G3DSA:3.30.70.240 1 65 1.9E-29 T 23-10-2018 A3L12_06445 0053684ec63ebde6f8617cc430308feb 84 Pfam PF09827 CRISPR associated protein Cas2 1 67 7.2E-22 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PIRSF PIRSF006648 1 253 2.6E-69 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 6.0E-114 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 1.8E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 1.8E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.8E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 1.8E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 1.8E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L12_06925 62673e1fb947effcae4147e638f0df3f 254 Pfam PF01061 ABC-2 type transporter 3 216 6.2E-43 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L12_05760 a763ba8e5858736c04e030edf22e3953 154 Gene3D G3DSA:1.25.40.10 49 153 3.5E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_05760 a763ba8e5858736c04e030edf22e3953 154 SUPERFAMILY SSF48452 60 141 1.24E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_06255 8b191cdf1686303ec018cccd582472a6 95 Gene3D G3DSA:1.20.1270.90 4 85 1.8E-24 T 23-10-2018 A3L12_06255 8b191cdf1686303ec018cccd582472a6 95 SUPERFAMILY SSF158372 4 85 1.29E-24 T 23-10-2018 IPR036809 AF1782-like superfamily A3L12_06255 8b191cdf1686303ec018cccd582472a6 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 1.5E-28 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A3L12_02785 b9e2e2ebdac47517da2af4167e6b231e 197 Pfam PF12389 Camelysin metallo-endopeptidase 23 197 1.8E-7 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L12_04235 1e2c2124b052980de80432eb40cb86b0 71 Pfam PF02082 Transcriptional regulator 15 63 1.7E-4 T 23-10-2018 IPR000944 Transcription regulator Rrf2-type A3L12_04235 1e2c2124b052980de80432eb40cb86b0 71 SUPERFAMILY SSF46785 11 58 9.23E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_02480 49486fea7f2008fcc41240c26b31663f 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.191 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02480 49486fea7f2008fcc41240c26b31663f 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 1.4E-69 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02480 49486fea7f2008fcc41240c26b31663f 214 Pfam PF01813 ATP synthase subunit D 13 206 9.5E-61 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_00350 a40c1701909c1f89cbcfb9997c004d82 230 SUPERFAMILY SSF56784 1 223 4.9E-34 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_00350 a40c1701909c1f89cbcfb9997c004d82 230 Gene3D G3DSA:3.40.50.1000 2 212 8.7E-60 T 23-10-2018 IPR023214 HAD superfamily A3L12_00350 a40c1701909c1f89cbcfb9997c004d82 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 94 196 6.1E-12 T 23-10-2018 A3L12_00350 a40c1701909c1f89cbcfb9997c004d82 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 137 189 4.8E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_00350 a40c1701909c1f89cbcfb9997c004d82 230 Gene3D G3DSA:1.10.150.400 14 89 8.7E-60 T 23-10-2018 A3L12_00120 d0c1cc62f84a8172d7697d5368051101 164 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 4.3E-21 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L12_00120 d0c1cc62f84a8172d7697d5368051101 164 SUPERFAMILY SSF54534 2 150 1.45E-46 T 23-10-2018 A3L12_00120 d0c1cc62f84a8172d7697d5368051101 164 Gene3D G3DSA:3.10.50.80 2 157 1.2E-54 T 23-10-2018 A3L12_01745 03eecdcd14b5da0190cbd1e978099886 371 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 321 5.2E-48 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L12_01745 03eecdcd14b5da0190cbd1e978099886 371 Gene3D G3DSA:3.40.720.10 1 369 5.7E-54 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_01745 03eecdcd14b5da0190cbd1e978099886 371 SUPERFAMILY SSF53649 2 358 1.26E-73 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_07925 ec97b1927a693d5afe129765d68b839f 232 SUPERFAMILY SSF53271 13 217 5.53E-56 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_07925 ec97b1927a693d5afe129765d68b839f 232 Gene3D G3DSA:3.40.50.2020 1 218 1.3E-59 T 23-10-2018 A3L12_07925 ec97b1927a693d5afe129765d68b839f 232 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 41.066 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L12_07925 ec97b1927a693d5afe129765d68b839f 232 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 1.7E-75 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L12_07925 ec97b1927a693d5afe129765d68b839f 232 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 7.6E-51 T 23-10-2018 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 Gene3D G3DSA:3.10.20.70 9 99 2.2E-20 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 90 6.2E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 13 437 6.8E-161 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 Pfam PF00120 Glutamine synthetase, catalytic domain 98 417 1.3E-121 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 Gene3D G3DSA:3.30.590.10 100 438 1.9E-122 T 23-10-2018 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 SMART SM01230 97 338 3.2E-130 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 SUPERFAMILY SSF54368 13 81 2.62E-19 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 221 236 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 SUPERFAMILY SSF55931 97 437 6.47E-117 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L12_02550 105a03ed1a8ee39911787c74a7aa7530 438 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L12_00980 bef0b85ca9612621e03b1165fb61d4cb 150 Gene3D G3DSA:3.30.1440.10 5 148 7.1E-47 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00980 bef0b85ca9612621e03b1165fb61d4cb 150 Pfam PF01877 RNA binding 9 130 5.2E-39 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L12_00980 bef0b85ca9612621e03b1165fb61d4cb 150 SUPERFAMILY SSF55282 7 148 2.18E-43 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 SUPERFAMILY SSF54631 7 121 4.67E-30 T 23-10-2018 A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 SMART SM00116 14 61 8.9E-10 T 23-10-2018 IPR000644 CBS domain A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 SMART SM00116 78 125 3.9E-4 T 23-10-2018 IPR000644 CBS domain A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 Gene3D G3DSA:3.10.580.10 1 135 8.8E-44 T 23-10-2018 A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 Pfam PF00571 CBS domain 10 60 1.3E-10 T 23-10-2018 IPR000644 CBS domain A3L12_07800 82b763d62365ce1f5bccb50eb6778aaa 135 Pfam PF00571 CBS domain 71 123 3.3E-13 T 23-10-2018 IPR000644 CBS domain A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 484 161.625 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 4.6E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 SUPERFAMILY SSF52317 193 370 7.8E-30 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 Gene3D G3DSA:3.40.50.300 2 240 5.3E-47 T 23-10-2018 A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 8.4E-152 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 SUPERFAMILY SSF52540 3 231 1.33E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 Gene3D G3DSA:3.40.50.880 247 403 2.6E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_04870 d3fa5ba8424500b470307fa8dc7f3e22 484 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 431 4.0E-49 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A3L12_07405 af227ee4df992a0b0f2082e1c1622e4f 114 Pfam PF01883 Iron-sulfur cluster assembly protein 25 85 4.0E-10 T 23-10-2018 IPR002744 MIP18 family-like A3L12_07405 af227ee4df992a0b0f2082e1c1622e4f 114 SUPERFAMILY SSF117916 24 87 4.58E-11 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_07405 af227ee4df992a0b0f2082e1c1622e4f 114 Gene3D G3DSA:3.30.300.130 22 106 6.5E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_01480 8d4a7b7702965edd38bf0b06bfe07618 442 Pfam PF13660 Domain of unknown function (DUF4147) 7 244 8.3E-80 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A3L12_01480 8d4a7b7702965edd38bf0b06bfe07618 442 SUPERFAMILY SSF82544 2 435 2.09E-135 T 23-10-2018 A3L12_01480 8d4a7b7702965edd38bf0b06bfe07618 442 Pfam PF05161 MOFRL family 325 428 4.7E-36 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 A3L12_01480 8d4a7b7702965edd38bf0b06bfe07618 442 Gene3D G3DSA:3.40.50.10180 23 268 5.8E-163 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 A3L12_01480 8d4a7b7702965edd38bf0b06bfe07618 442 Gene3D G3DSA:3.40.1480.10 269 432 5.8E-163 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 Pfam PF02223 Thymidylate kinase 7 196 5.3E-54 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 4.1E-57 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 Hamap MF_00165 Thymidylate kinase [tmk]. 3 204 28.354 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 ProSitePatterns PS01331 Thymidylate kinase signature. 98 110 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 Gene3D G3DSA:3.40.50.300 1 204 6.0E-68 T 23-10-2018 A3L12_01605 f7b200c687189a2d39862f9f7b997597 207 SUPERFAMILY SSF52540 3 201 8.46E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04795 8067d2ccb7fb6e410f5ab91177897bfd 313 PIRSF PIRSF000535 1 311 8.5E-79 T 23-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A3L12_04795 8067d2ccb7fb6e410f5ab91177897bfd 313 Pfam PF00294 pfkB family carbohydrate kinase 12 292 2.5E-49 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L12_04795 8067d2ccb7fb6e410f5ab91177897bfd 313 SUPERFAMILY SSF53613 1 293 2.34E-58 T 23-10-2018 IPR029056 Ribokinase-like A3L12_04795 8067d2ccb7fb6e410f5ab91177897bfd 313 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 308 1.5E-88 T 23-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A3L12_04795 8067d2ccb7fb6e410f5ab91177897bfd 313 Gene3D G3DSA:3.40.1190.20 1 311 2.3E-89 T 23-10-2018 IPR029056 Ribokinase-like A3L12_01210 c8d769e8aef6eeeb738b5eaf1426fb3f 211 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 199 1.4E-12 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L12_01210 c8d769e8aef6eeeb738b5eaf1426fb3f 211 Gene3D G3DSA:3.40.50.11570 6 207 1.3E-17 T 23-10-2018 A3L12_03345 33c9b5d1ccaed1a354e7ec477b2a0b3c 111 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 1.1E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_03345 33c9b5d1ccaed1a354e7ec477b2a0b3c 111 Gene3D G3DSA:1.10.10.10 2 109 2.9E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03345 33c9b5d1ccaed1a354e7ec477b2a0b3c 111 SUPERFAMILY SSF46785 4 107 1.81E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 Gene3D G3DSA:3.40.50.11750 16 260 5.5E-108 T 23-10-2018 A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 Gene3D G3DSA:3.40.50.11740 59 300 5.5E-108 T 23-10-2018 A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 Gene3D G3DSA:1.10.10.2140 315 367 1.5E-25 T 23-10-2018 A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 364 7.1E-130 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 Pfam PF01924 Hydrogenase formation hypA family 10 364 2.0E-134 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L12_01885 36fd35fb5dd4df435162ae48ea6b0be5 367 PIRSF PIRSF005622 1 367 3.6E-141 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L12_04210 bd70408c609afd1e415cb1231f1d0ff4 209 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 187 5.0E-43 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L12_04385 284733ed81823964fbe5557fc4ae5425 158 SUPERFAMILY SSF51306 36 122 1.73E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L12_04385 284733ed81823964fbe5557fc4ae5425 158 Pfam PF00717 Peptidase S24-like 39 89 8.8E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L12_04385 284733ed81823964fbe5557fc4ae5425 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 1.5E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_04385 284733ed81823964fbe5557fc4ae5425 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 1.5E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_04385 284733ed81823964fbe5557fc4ae5425 158 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 150 5.3E-34 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_07010 a3f75f46f83361e0952dce2f8db80183 196 SUPERFAMILY SSF53448 17 132 2.25E-9 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_07010 a3f75f46f83361e0952dce2f8db80183 196 Gene3D G3DSA:3.90.550.10 14 196 2.5E-12 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_07010 a3f75f46f83361e0952dce2f8db80183 196 Pfam PF12804 MobA-like NTP transferase domain 17 150 2.5E-6 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L12_06415 cda1ee728da2b2bfcd9f77b0c4f79c90 315 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 273 4.6E-83 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L12_06415 cda1ee728da2b2bfcd9f77b0c4f79c90 315 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 6 258 2.5E-44 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L12_06415 cda1ee728da2b2bfcd9f77b0c4f79c90 315 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 2 281 2.1E-105 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern A3L12_04990 028714b5d6518f7685ea85e30f653528 237 Gene3D G3DSA:3.40.50.1860 6 220 2.7E-88 T 23-10-2018 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 231 7.0E-106 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 6.8E-63 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 SUPERFAMILY SSF53681 119 227 9.48E-27 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 Gene3D G3DSA:3.40.50.1860 107 214 2.7E-88 T 23-10-2018 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_04990 028714b5d6518f7685ea85e30f653528 237 SUPERFAMILY SSF53681 4 117 4.91E-36 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 Gene3D G3DSA:1.10.3720.10 330 599 1.2E-35 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 305 1.6E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 417 601 9.2E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 SUPERFAMILY SSF161098 24 312 1.4E-42 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 SUPERFAMILY SSF161098 333 605 3.18E-40 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_06950 4e4cb1394587a69a80a2bccc3d2c7556 612 Gene3D G3DSA:1.10.3720.10 20 317 1.6E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01790 114420e5c340571e19acfde3eb987cc3 59 SUPERFAMILY SSF144210 4 51 1.57E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L12_01790 114420e5c340571e19acfde3eb987cc3 59 Gene3D G3DSA:2.20.28.40 1 59 1.7E-30 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L12_01790 114420e5c340571e19acfde3eb987cc3 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.327 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A3L12_01790 114420e5c340571e19acfde3eb987cc3 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 1.0E-27 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L12_03925 007632c25250e3afe2046aeb3f49a2b6 415 Pfam PF01882 Protein of unknown function DUF58 187 271 1.5E-25 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 351 2.2E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 SMART SM01027 433 557 1.2E-56 T 23-10-2018 IPR022712 Beta-Casp domain A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Gene3D G3DSA:3.30.300.20 72 142 4.3E-63 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Pfam PF10996 Beta-Casp domain 433 556 3.9E-23 T 23-10-2018 IPR022712 Beta-Casp domain A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Gene3D G3DSA:3.30.300.230 15 175 4.3E-63 T 23-10-2018 A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 SMART SM00849 198 428 7.7E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 SMART SM00322 102 169 2.8E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Gene3D G3DSA:3.60.15.10 191 627 1.6E-164 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 3.0E-17 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 SUPERFAMILY SSF54814 97 141 2.68E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 SUPERFAMILY SSF56281 183 647 8.44E-133 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 9.2E-300 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Pfam PF17214 KH domain 9 76 1.5E-26 T 23-10-2018 IPR033769 KH domain, archaeal A3L12_01060 323d96cf89c45bd0aca796c7a6d1179f 648 Gene3D G3DSA:3.40.50.10890 401 588 1.6E-164 T 23-10-2018 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 Gene3D G3DSA:3.60.20.10 1 199 2.4E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 3.6E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 PRINTS PR00141 Proteasome component signature 146 157 9.5E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 PRINTS PR00141 Proteasome component signature 135 146 9.5E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 PRINTS PR00141 Proteasome component signature 15 30 9.5E-6 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.109 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 SUPERFAMILY SSF56235 2 193 1.1E-56 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_03840 74477b1144a22b3c72198455df6e0f3a 200 Pfam PF00227 Proteasome subunit 5 185 2.5E-49 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Pfam PF00571 CBS domain 67 116 1.0E-11 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Pfam PF00571 CBS domain 224 279 1.8E-12 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Pfam PF00571 CBS domain 3 55 8.6E-7 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Pfam PF00571 CBS domain 140 181 9.6E-5 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Gene3D G3DSA:3.10.580.10 1 122 2.5E-37 T 23-10-2018 A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SUPERFAMILY SSF54631 2 118 3.92E-26 T 23-10-2018 A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 Gene3D G3DSA:3.10.580.10 123 281 1.8E-35 T 23-10-2018 A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SMART SM00116 139 184 28.0 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SMART SM00116 231 279 1.2E-9 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SMART SM00116 10 59 2.8E-4 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SMART SM00116 70 118 1.8E-9 T 23-10-2018 IPR000644 CBS domain A3L12_00490 630edbac38077d01d16e197cb564e3a3 281 SUPERFAMILY SSF54631 125 278 1.64E-30 T 23-10-2018 A3L12_00315 f3da83936aeaab68c32aa2aff61b2933 281 Pfam PF01261 Xylose isomerase-like TIM barrel 29 239 1.4E-19 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L12_00315 f3da83936aeaab68c32aa2aff61b2933 281 Gene3D G3DSA:3.20.20.150 12 280 5.5E-42 T 23-10-2018 A3L12_00315 f3da83936aeaab68c32aa2aff61b2933 281 SUPERFAMILY SSF51658 7 278 1.9E-62 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L12_00315 f3da83936aeaab68c32aa2aff61b2933 281 SMART SM00518 4 276 2.6E-85 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L12_01730 7608175ef2092312516775bd4034c86d 145 Gene3D G3DSA:3.30.300.20 2 73 4.6E-29 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_01730 7608175ef2092312516775bd4034c86d 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 3.2E-59 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L12_01730 7608175ef2092312516775bd4034c86d 145 SUPERFAMILY SSF54814 89 141 2.29E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_01730 7608175ef2092312516775bd4034c86d 145 Gene3D G3DSA:3.30.300.20 74 144 9.2E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_01730 7608175ef2092312516775bd4034c86d 145 Pfam PF07650 KH domain 14 93 9.6E-18 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01730 7608175ef2092312516775bd4034c86d 145 SUPERFAMILY SSF54814 13 74 5.23E-12 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_01730 7608175ef2092312516775bd4034c86d 145 SMART SM00322 32 115 0.0029 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L12_01730 7608175ef2092312516775bd4034c86d 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 29.985 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L12_01970 f990655a9e35d210605a41590b1e8020 393 SUPERFAMILY SSF51905 1 337 1.9E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01970 f990655a9e35d210605a41590b1e8020 393 Gene3D G3DSA:3.30.9.10 69 356 1.0E-109 T 23-10-2018 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 387 39.104 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.1E-10 T 23-10-2018 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 3.1E-10 T 23-10-2018 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.1E-10 T 23-10-2018 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 Pfam PF01494 FAD binding domain 3 319 1.5E-14 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L12_01970 f990655a9e35d210605a41590b1e8020 393 Gene3D G3DSA:3.50.50.60 3 338 1.0E-109 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01970 f990655a9e35d210605a41590b1e8020 393 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 301 3.3E-75 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L12_00935 31e7cc9d18a379dbd3d58dfca87b2672 259 SUPERFAMILY SSF53633 1 257 1.7E-36 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_00935 31e7cc9d18a379dbd3d58dfca87b2672 259 Pfam PF00696 Amino acid kinase family 2 228 4.4E-45 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L12_00935 31e7cc9d18a379dbd3d58dfca87b2672 259 Gene3D G3DSA:3.40.1160.10 1 258 2.4E-65 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L12_00935 31e7cc9d18a379dbd3d58dfca87b2672 259 PIRSF PIRSF016496 1 259 9.6E-81 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 SMART SM01206 3 226 6.8E-143 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 Gene3D G3DSA:3.30.200.20 1 50 6.2E-22 T 23-10-2018 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 43.868 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 98 115 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 23 42 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 153 182 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 46 65 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 73 94 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 123 152 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PRINTS PR00052 Fibrillarin signature 204 225 5.2E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 Gene3D G3DSA:3.40.50.150 51 226 6.3E-75 T 23-10-2018 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 Pfam PF01269 Fibrillarin 5 224 2.1E-99 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 SUPERFAMILY SSF53335 4 225 7.63E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A3L12_02265 3736a79147d12cdf2e265b14c4aaa776 226 PIRSF PIRSF006540 1 226 2.6E-99 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L12_05665 b49a520a2a017c751d30eaba56a61a85 124 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 4.5E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_05665 b49a520a2a017c751d30eaba56a61a85 124 Pfam PF03334 Na+/H+ antiporter subunit 11 95 1.0E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_02980 5de45c816a1d45f7508d078618eb8832 317 Gene3D G3DSA:3.90.25.10 181 222 2.4E-12 T 23-10-2018 A3L12_02980 5de45c816a1d45f7508d078618eb8832 317 Gene3D G3DSA:3.90.25.10 223 317 7.4E-26 T 23-10-2018 A3L12_02980 5de45c816a1d45f7508d078618eb8832 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 7.0E-58 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L12_02980 5de45c816a1d45f7508d078618eb8832 317 SUPERFAMILY SSF51735 1 315 5.5E-88 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_02980 5de45c816a1d45f7508d078618eb8832 317 Gene3D G3DSA:3.40.50.720 1 180 4.9E-53 T 23-10-2018 A3L12_04620 50ec2d4831373e47c1b8b2a5ac4cf706 229 Gene3D G3DSA:3.40.50.720 2 229 2.0E-70 T 23-10-2018 A3L12_04620 50ec2d4831373e47c1b8b2a5ac4cf706 229 Pfam PF00899 ThiF family 7 228 5.9E-55 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L12_04620 50ec2d4831373e47c1b8b2a5ac4cf706 229 SUPERFAMILY SSF69572 4 227 1.06E-76 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L12_00720 7df5374371f4388d3e47de7140182151 175 Pfam PF01956 Integral membrane protein DUF106 12 173 1.0E-26 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L12_00720 7df5374371f4388d3e47de7140182151 175 SMART SM01415 10 174 1.6E-20 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L12_00125 fecb568a4a0b22e4630b6295e8f455e2 163 Gene3D G3DSA:2.40.50.100 96 162 1.5E-28 T 23-10-2018 A3L12_00125 fecb568a4a0b22e4630b6295e8f455e2 163 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 1 162 4.8E-49 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L12_06480 29ef041dd2cd7806c60342d448445c17 71 SUPERFAMILY SSF50182 6 71 2.13E-26 T 23-10-2018 IPR010920 LSM domain superfamily A3L12_06480 29ef041dd2cd7806c60342d448445c17 71 Gene3D G3DSA:2.30.30.100 2 71 2.6E-28 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 SUPERFAMILY SSF51971 157 408 2.06E-68 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 3.2E-206 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 Gene3D G3DSA:1.10.1060.10 3 154 5.2E-40 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 7.7E-25 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 7.7E-25 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 7.7E-25 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 7.7E-25 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 7.7E-25 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 2.8E-15 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 2.8E-15 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 2.8E-15 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 2.8E-15 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 SUPERFAMILY SSF46548 8 168 1.67E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 SUPERFAMILY SSF51971 388 473 1.41E-14 T 23-10-2018 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 Gene3D G3DSA:3.50.50.60 294 479 3.1E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 Gene3D G3DSA:3.50.50.60 155 284 2.2E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 1.2E-37 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L12_01225 ed0b9b6fb1d9b4543b7cc7c516b3817a 479 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 1.2E-37 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L12_07295 0c71b3524d6ec7910d595a62e167e206 147 Pfam PF02996 Prefoldin subunit 18 138 1.8E-23 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L12_07295 0c71b3524d6ec7910d595a62e167e206 147 Gene3D G3DSA:1.10.287.370 1 144 2.2E-43 T 23-10-2018 IPR009053 Prefoldin A3L12_07295 0c71b3524d6ec7910d595a62e167e206 147 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 138 15.587 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L12_07295 0c71b3524d6ec7910d595a62e167e206 147 SUPERFAMILY SSF46579 7 140 4.71E-28 T 23-10-2018 A3L12_07295 0c71b3524d6ec7910d595a62e167e206 147 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 138 1.9E-32 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 Gene3D G3DSA:2.30.30.60 117 166 2.9E-16 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 Pfam PF05552 Conserved TM helix 17 48 3.7E-8 T 23-10-2018 IPR008910 Conserved TM helix A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 Gene3D G3DSA:3.30.70.100 167 261 1.4E-30 T 23-10-2018 A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 SUPERFAMILY SSF50182 101 167 9.15E-16 T 23-10-2018 IPR010920 LSM domain superfamily A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 SUPERFAMILY SSF82689 168 266 7.98E-34 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 SUPERFAMILY SSF82861 16 100 4.18E-10 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L12_08045 3533986a6bbfb2c20d8449d369b59743 270 Pfam PF00924 Mechanosensitive ion channel 60 256 8.4E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L12_02060 5c8834c8cd0c7cd5ab2cf8e28d49fd60 102 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 9.0E-17 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A3L12_02060 5c8834c8cd0c7cd5ab2cf8e28d49fd60 102 SUPERFAMILY SSF50447 1 72 8.12E-16 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_02060 5c8834c8cd0c7cd5ab2cf8e28d49fd60 102 Gene3D G3DSA:2.40.10.230 1 75 4.1E-24 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A3L12_02060 5c8834c8cd0c7cd5ab2cf8e28d49fd60 102 Pfam PF04410 Gar1/Naf1 RNA binding region 3 74 1.4E-8 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A3L12_05930 fe721af7ecca0ab211850699347038f8 439 Gene3D G3DSA:1.20.1530.20 5 415 5.3E-67 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_05930 fe721af7ecca0ab211850699347038f8 439 Pfam PF00999 Sodium/hydrogen exchanger family 10 404 7.7E-44 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L12_07720 9cfbb840bdc0ca4a74bcd390ea6be22b 155 SUPERFAMILY SSF55040 11 154 3.79E-51 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_07720 9cfbb840bdc0ca4a74bcd390ea6be22b 155 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 137 5.9E-55 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_07720 9cfbb840bdc0ca4a74bcd390ea6be22b 155 Gene3D G3DSA:3.30.70.640 1 155 1.7E-67 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_07720 9cfbb840bdc0ca4a74bcd390ea6be22b 155 Pfam PF01967 MoaC family 13 153 2.1E-51 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_07720 9cfbb840bdc0ca4a74bcd390ea6be22b 155 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 8 153 39.505 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A3L12_06645 69b329eaf02978694a479b1537e5b8cb 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 236 2.1E-99 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L12_06645 69b329eaf02978694a479b1537e5b8cb 245 PIRSF PIRSF003092 1 241 2.2E-55 T 23-10-2018 IPR025501 ATP binding protein MinD A3L12_06645 69b329eaf02978694a479b1537e5b8cb 245 Pfam PF13614 AAA domain 3 145 4.6E-27 T 23-10-2018 IPR025669 AAA domain A3L12_06645 69b329eaf02978694a479b1537e5b8cb 245 SUPERFAMILY SSF52540 1 235 3.64E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06645 69b329eaf02978694a479b1537e5b8cb 245 Gene3D G3DSA:3.40.50.300 1 236 9.8E-74 T 23-10-2018 A3L12_03770 0add196d064218d51397aa1050d64cb0 476 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 153 1.3E-13 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L12_03770 0add196d064218d51397aa1050d64cb0 476 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 462 33.748 T 23-10-2018 IPR023935 Replication factor C, large subunit A3L12_03770 0add196d064218d51397aa1050d64cb0 476 SMART SM00382 42 159 1.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_03770 0add196d064218d51397aa1050d64cb0 476 SUPERFAMILY SSF52540 4 212 1.39E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03770 0add196d064218d51397aa1050d64cb0 476 Gene3D G3DSA:3.40.50.300 4 157 1.5E-35 T 23-10-2018 A3L12_03770 0add196d064218d51397aa1050d64cb0 476 Gene3D G3DSA:1.10.8.60 160 222 1.2E-10 T 23-10-2018 A3L12_00070 360007d12ec0320d963e489bc80f57dd 254 SUPERFAMILY SSF51658 21 249 4.06E-26 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L12_00070 360007d12ec0320d963e489bc80f57dd 254 Pfam PF01261 Xylose isomerase-like TIM barrel 22 210 8.9E-17 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L12_00070 360007d12ec0320d963e489bc80f57dd 254 Gene3D G3DSA:3.20.20.150 13 251 2.0E-33 T 23-10-2018 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 2.5E-12 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 Gene3D G3DSA:3.40.50.150 62 282 3.0E-75 T 23-10-2018 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 280 37.212 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 SUPERFAMILY SSF53335 10 280 7.21E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 TIGRFAM TIGR00417 speE: spermidine synthase 10 274 3.2E-81 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 Gene3D G3DSA:2.30.140.10 6 60 3.9E-23 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L12_02180 0960b1d2936ad56a6ef39fa52a00da30 283 Pfam PF01564 Spermine/spermidine synthase domain 64 241 1.4E-51 T 23-10-2018 A3L12_02765 2247f7cf90b3bf1930c7821a2cd38bd4 153 Pfam PF00156 Phosphoribosyl transferase domain 13 149 3.0E-27 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_02765 2247f7cf90b3bf1930c7821a2cd38bd4 153 Gene3D G3DSA:3.40.50.2020 1 153 5.9E-54 T 23-10-2018 A3L12_02765 2247f7cf90b3bf1930c7821a2cd38bd4 153 SUPERFAMILY SSF53271 2 146 4.2E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_03080 bb59601f450492d04a93b160e21b0de8 219 Pfam PF01259 SAICAR synthetase 5 205 1.2E-29 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_03080 bb59601f450492d04a93b160e21b0de8 219 Gene3D G3DSA:3.30.470.20 87 206 4.7E-55 T 23-10-2018 A3L12_03080 bb59601f450492d04a93b160e21b0de8 219 Gene3D G3DSA:3.30.200.20 5 86 4.7E-55 T 23-10-2018 A3L12_03080 bb59601f450492d04a93b160e21b0de8 219 SUPERFAMILY SSF56104 2 206 2.26E-47 T 23-10-2018 A3L12_03080 bb59601f450492d04a93b160e21b0de8 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 18.951 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_00665 84b14bba53c3b9fa0db3f50058a4fab0 56 Gene3D G3DSA:4.10.830.10 1 56 1.5E-20 T 23-10-2018 A3L12_00665 84b14bba53c3b9fa0db3f50058a4fab0 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.461 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A3L12_00665 84b14bba53c3b9fa0db3f50058a4fab0 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 6.5E-10 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00665 84b14bba53c3b9fa0db3f50058a4fab0 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05240 78c5b56843c0dfbbe382f6f4c367842b 215 Gene3D G3DSA:3.40.50.2020 6 175 5.9E-41 T 23-10-2018 A3L12_05240 78c5b56843c0dfbbe382f6f4c367842b 215 Pfam PF00156 Phosphoribosyl transferase domain 18 152 1.9E-20 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_05240 78c5b56843c0dfbbe382f6f4c367842b 215 SUPERFAMILY SSF53271 7 190 4.98E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_00480 9911f4aaee7c9ae141979d232cc0a2a8 174 Pfam PF04266 ASCH domain 6 86 2.0E-6 T 23-10-2018 IPR007374 ASCH domain A3L12_00480 9911f4aaee7c9ae141979d232cc0a2a8 174 SUPERFAMILY SSF88697 3 146 2.15E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 Pfam PF02926 THUMP domain 57 160 3.6E-9 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 Gene3D G3DSA:3.30.70.2510 162 275 2.7E-29 T 23-10-2018 A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 385 1.1E-139 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 SUPERFAMILY SSF55120 271 383 1.15E-12 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 50.925 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L12_06030 fca54a1e2024bde3d468e81ba4dca4b1 386 Gene3D G3DSA:3.30.70.3190 276 384 2.8E-28 T 23-10-2018 A3L12_07000 0d9f7b865745b1afba982b5f5ea5729b 263 SMART SM00382 26 210 2.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_07000 0d9f7b865745b1afba982b5f5ea5729b 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_07000 0d9f7b865745b1afba982b5f5ea5729b 263 Pfam PF00005 ABC transporter 27 162 2.4E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_07000 0d9f7b865745b1afba982b5f5ea5729b 263 Gene3D G3DSA:3.40.50.300 1 250 2.2E-69 T 23-10-2018 A3L12_07000 0d9f7b865745b1afba982b5f5ea5729b 263 SUPERFAMILY SSF52540 2 218 3.91E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 1.3E-34 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 137 2.8E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 SUPERFAMILY SSF111038 1 137 4.71E-43 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 PIRSF PIRSF004681 1 137 3.9E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 Gene3D G3DSA:2.60.120.460 1 137 7.5E-48 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L12_03860 97f7e23de72ddfdf8393643c6cb76d10 137 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 98 116 - T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 SMART SM00382 39 230 2.6E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 SUPERFAMILY SSF52540 5 251 2.42E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 Pfam PF00005 ABC transporter 31 181 2.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 300 2.9E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 3.1E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 Gene3D G3DSA:3.40.50.300 3 325 2.0E-102 T 23-10-2018 A3L12_01175 2d76b1d703de788410ffd99634f0c7de 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_00355 26cb3f0464a6a61459f3e493434a1e15 340 SUPERFAMILY SSF160945 102 335 3.01E-82 T 23-10-2018 A3L12_00355 26cb3f0464a6a61459f3e493434a1e15 340 Pfam PF11536 Protein of unknown function (DUF3226) 103 331 1.5E-75 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L12_00355 26cb3f0464a6a61459f3e493434a1e15 340 Gene3D G3DSA:3.40.50.10620 101 325 7.3E-63 T 23-10-2018 A3L12_00355 26cb3f0464a6a61459f3e493434a1e15 340 ProDom PD038575 MJECL12 PLASMID PH0156 102 323 5.0E-79 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L12_00355 26cb3f0464a6a61459f3e493434a1e15 340 Gene3D G3DSA:1.10.3490.10 236 324 7.3E-63 T 23-10-2018 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 SUPERFAMILY SSF54826 1 123 6.54E-31 T 23-10-2018 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 SMART SM01192 124 340 9.9E-14 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 247 334 1.1E-8 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 SUPERFAMILY SSF51604 126 337 1.11E-28 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 SMART SM01193 4 119 4.1E-36 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 Gene3D G3DSA:3.30.390.10 1 111 6.1E-22 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 Pfam PF03952 Enolase, N-terminal domain 4 119 2.9E-23 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 Gene3D G3DSA:3.20.20.120 220 339 1.0E-11 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 PRINTS PR00148 Enolase signature 92 108 8.1E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00810 061d7a98595eeffdf35b10d35d41f8e1 341 PRINTS PR00148 Enolase signature 316 330 8.1E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 7.9E-98 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 Pfam PF00318 Ribosomal protein S2 12 103 3.1E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 Pfam PF00318 Ribosomal protein S2 110 174 1.4E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 4.5E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 Gene3D G3DSA:3.40.50.10490 7 201 5.2E-71 T 23-10-2018 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 SUPERFAMILY SSF52313 3 192 1.2E-61 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A3L12_00815 ed70709ef25aae04396613aa53faebfd 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.354 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 Pfam PF00935 Ribosomal protein L44 16 92 2.7E-25 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.786 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 SUPERFAMILY SSF57829 1 93 6.41E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 Gene3D G3DSA:3.10.450.80 1 93 1.8E-30 T 23-10-2018 A3L12_01775 ca1d26964783fd0fe9327198240bbdb5 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 3.0E-38 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 Gene3D G3DSA:3.30.300.10 30 154 1.6E-168 T 23-10-2018 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 Gene3D G3DSA:3.30.300.280 16 398 1.6E-168 T 23-10-2018 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 51.594 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 400 2.7E-176 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L12_05415 db6d14a0883d52217528021bf46fad16 405 Gene3D G3DSA:3.30.300.340 18 286 1.6E-168 T 23-10-2018 A3L12_06130 164cad735e781e1a20b34f0b1d11f937 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L12_06130 164cad735e781e1a20b34f0b1d11f937 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 2.8E-19 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A3L12_06130 164cad735e781e1a20b34f0b1d11f937 95 SUPERFAMILY SSF55257 1 92 5.63E-24 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_06130 164cad735e781e1a20b34f0b1d11f937 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.333 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_06130 164cad735e781e1a20b34f0b1d11f937 95 Gene3D G3DSA:3.30.1360.10 1 94 1.8E-32 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_03975 d3348ff8ee6d65f31ce2b115bd9d9f17 215 SUPERFAMILY SSF109755 19 209 3.14E-9 T 23-10-2018 A3L12_03975 d3348ff8ee6d65f31ce2b115bd9d9f17 215 Gene3D G3DSA:1.20.58.220 3 212 5.8E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_03975 d3348ff8ee6d65f31ce2b115bd9d9f17 215 Pfam PF01865 Protein of unknown function DUF47 7 211 1.9E-43 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L12_03975 d3348ff8ee6d65f31ce2b115bd9d9f17 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 213 6.1E-42 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 262 2.1E-55 T 23-10-2018 A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 SUPERFAMILY SSF51735 14 263 3.74E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 Gene3D G3DSA:3.40.50.720 2 264 1.9E-71 T 23-10-2018 A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 7.9E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 7.9E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 7.9E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_01240 2e246133db4adca3b0aaa7f21712d9cf 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.5E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L12_00015 5971198d82b0a58cdd30f940fbd61830 185 SUPERFAMILY SSF46785 3 123 1.73E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00015 5971198d82b0a58cdd30f940fbd61830 185 SMART SM00418 11 87 1.4E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_00015 5971198d82b0a58cdd30f940fbd61830 185 Gene3D G3DSA:1.10.10.10 1 85 4.4E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_00015 5971198d82b0a58cdd30f940fbd61830 185 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 2.3E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_07035 7ccf77b355ab9b980ad18cad88b5e0bb 309 Gene3D G3DSA:1.20.1420.30 35 296 8.2E-78 T 23-10-2018 A3L12_07035 7ccf77b355ab9b980ad18cad88b5e0bb 309 Gene3D G3DSA:1.20.58.1130 8 195 8.2E-78 T 23-10-2018 A3L12_07035 7ccf77b355ab9b980ad18cad88b5e0bb 309 Pfam PF01699 Sodium/calcium exchanger protein 165 304 7.7E-23 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L12_07035 7ccf77b355ab9b980ad18cad88b5e0bb 309 Pfam PF01699 Sodium/calcium exchanger protein 5 143 2.2E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L12_07035 7ccf77b355ab9b980ad18cad88b5e0bb 309 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 297 8.7E-60 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A3L12_03550 9c5e4d430e6a892531373546c32bf229 189 SUPERFAMILY SSF88697 2 103 6.83E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_03550 9c5e4d430e6a892531373546c32bf229 189 Pfam PF04266 ASCH domain 4 104 2.0E-16 T 23-10-2018 IPR007374 ASCH domain A3L12_03550 9c5e4d430e6a892531373546c32bf229 189 SMART SM01022 4 104 8.2E-25 T 23-10-2018 IPR007374 ASCH domain A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.394 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 Gene3D G3DSA:3.30.1330.30 1 101 3.1E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 1.2E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 SUPERFAMILY SSF55315 4 96 9.06E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_01725 20e7ac563db5f994b4dd012aa1d9546d 101 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 SUPERFAMILY SSF53335 2 422 1.92E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07350 ca87cc83e2d186391b54657426d16436 776 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 Pfam PF07669 Eco57I restriction-modification methylase 295 391 6.9E-6 T 23-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 6 20 1.2E-13 T 23-10-2018 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 1.2E-13 T 23-10-2018 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 336 360 1.2E-13 T 23-10-2018 A3L12_07350 ca87cc83e2d186391b54657426d16436 776 Gene3D G3DSA:3.40.50.150 193 431 5.4E-21 T 23-10-2018 A3L12_02410 f6d98ac707888f324b0879236208eef9 246 SUPERFAMILY SSF52540 2 234 5.91E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02410 f6d98ac707888f324b0879236208eef9 246 Gene3D G3DSA:3.40.50.300 1 246 9.0E-81 T 23-10-2018 A3L12_02410 f6d98ac707888f324b0879236208eef9 246 PRINTS PR01874 DNA repair protein radA signature 134 158 1.4E-9 T 23-10-2018 A3L12_02410 f6d98ac707888f324b0879236208eef9 246 PRINTS PR01874 DNA repair protein radA signature 13 41 1.4E-9 T 23-10-2018 A3L12_02410 f6d98ac707888f324b0879236208eef9 246 PRINTS PR01874 DNA repair protein radA signature 55 72 1.4E-9 T 23-10-2018 A3L12_02410 f6d98ac707888f324b0879236208eef9 246 Pfam PF06745 KaiC 4 235 1.5E-91 T 23-10-2018 IPR014774 KaiC-like domain A3L12_02410 f6d98ac707888f324b0879236208eef9 246 Hamap MF_01076 UPF0273 protein . 1 244 63.449 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L12_02410 f6d98ac707888f324b0879236208eef9 246 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 1 238 9.5E-140 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.818 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 SMART SM00531 19 158 3.4E-53 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 Gene3D G3DSA:1.10.10.10 3 87 4.4E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 SUPERFAMILY SSF46785 6 87 1.33E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 167 5.0E-49 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 PIRSF PIRSF006373 1 173 6.4E-70 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L12_04065 78c434f2a5cb9208bb9751ee23da3816 173 Pfam PF02002 TFIIE alpha subunit 11 111 2.4E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L12_07680 b736e24c3bee0c8c090e10ebd4cb0292 318 SMART SM00530 130 185 2.6E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_07680 b736e24c3bee0c8c090e10ebd4cb0292 318 SUPERFAMILY SSF47413 126 186 1.5E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L12_07680 b736e24c3bee0c8c090e10ebd4cb0292 318 Pfam PF01381 Helix-turn-helix 131 184 5.3E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L12_07680 b736e24c3bee0c8c090e10ebd4cb0292 318 Gene3D G3DSA:1.10.260.40 128 186 6.8E-13 T 23-10-2018 A3L12_07680 b736e24c3bee0c8c090e10ebd4cb0292 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.207 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A3L12_05310 cfb95401157859d5b41419a5a0aba8a2 89 Pfam PF12838 4Fe-4S dicluster domain 33 81 5.5E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_05310 cfb95401157859d5b41419a5a0aba8a2 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_05310 cfb95401157859d5b41419a5a0aba8a2 89 SUPERFAMILY SSF54862 24 87 9.71E-16 T 23-10-2018 A3L12_05310 cfb95401157859d5b41419a5a0aba8a2 89 Gene3D G3DSA:3.30.70.20 2 89 1.8E-17 T 23-10-2018 A3L12_05310 cfb95401157859d5b41419a5a0aba8a2 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 70 81 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_03935 f37d2087cdffea8f0b51035401df2858 225 Gene3D G3DSA:3.40.50.11570 2 214 1.8E-64 T 23-10-2018 A3L12_03935 f37d2087cdffea8f0b51035401df2858 225 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 209 1.3E-65 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 Gene3D G3DSA:3.40.630.10 11 332 2.4E-109 T 23-10-2018 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 Pfam PF05343 M42 glutamyl aminopeptidase 50 327 9.4E-69 T 23-10-2018 IPR008007 Peptidase M42 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 PIRSF PIRSF001123 1 336 5.1E-34 T 23-10-2018 IPR008007 Peptidase M42 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 Gene3D G3DSA:2.40.30.40 70 164 2.4E-109 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 SUPERFAMILY SSF101821 67 178 2.29E-25 T 23-10-2018 A3L12_05165 0ed0b11b52cf36afb187a76363cbe61f 338 SUPERFAMILY SSF53187 2 334 6.29E-46 T 23-10-2018 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 Gene3D G3DSA:3.40.50.300 12 432 1.1E-86 T 23-10-2018 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 Pfam PF13086 AAA domain 172 421 6.1E-52 T 23-10-2018 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 SUPERFAMILY SSF52540 171 633 9.91E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 17 648 5.8E-242 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 Gene3D G3DSA:3.40.50.300 449 653 1.7E-59 T 23-10-2018 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 Gene3D G3DSA:2.40.30.270 31 125 1.1E-86 T 23-10-2018 A3L12_03025 9f0d9371ad157ca2593a58e712eb6a37 656 Pfam PF13087 AAA domain 426 625 5.6E-56 T 23-10-2018 A3L12_06425 b0ea177565fb851702d865aae84b977c 402 TIGRFAM TIGR02671 cas_csx9: CRISPR-associated protein Cas8a2/Csx9, subtype I-A/APERN 23 402 1.0E-180 T 23-10-2018 IPR013488 CRISPR-associated protein Csx9 A3L12_06425 b0ea177565fb851702d865aae84b977c 402 Pfam PF09658 CRISPR-associated protein (Cas_Csx9) 23 401 4.8E-182 T 23-10-2018 IPR013488 CRISPR-associated protein Csx9 A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 Gene3D G3DSA:3.40.50.150 63 252 1.4E-63 T 23-10-2018 A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 SUPERFAMILY SSF53335 2 251 5.98E-75 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 233 5.4E-25 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 Gene3D G3DSA:3.10.330.20 1 61 1.7E-23 T 23-10-2018 A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 2 46 7.9E-9 T 23-10-2018 A3L12_01215 234012426dc56f003ecd6c16f60c05d2 252 PIRSF PIRSF017269 1 252 2.1E-76 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L12_07960 36c883befd9546719013924917a5fd29 602 Gene3D G3DSA:3.60.20.10 2 241 2.7E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_07960 36c883befd9546719013924917a5fd29 602 Pfam PF01380 SIS domain 285 412 9.0E-33 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L12_07960 36c883befd9546719013924917a5fd29 602 Pfam PF01380 SIS domain 463 584 6.3E-20 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L12_07960 36c883befd9546719013924917a5fd29 602 SUPERFAMILY SSF56235 2 228 1.03E-74 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_07960 36c883befd9546719013924917a5fd29 602 Gene3D G3DSA:3.40.50.10490 442 587 1.8E-132 T 23-10-2018 A3L12_07960 36c883befd9546719013924917a5fd29 602 Gene3D G3DSA:3.40.50.10490 251 601 1.8E-132 T 23-10-2018 A3L12_07960 36c883befd9546719013924917a5fd29 602 Pfam PF13522 Glutamine amidotransferase domain 64 185 1.6E-22 T 23-10-2018 A3L12_07960 36c883befd9546719013924917a5fd29 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 7.2E-242 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L12_07960 36c883befd9546719013924917a5fd29 602 SUPERFAMILY SSF53697 247 602 8.54E-110 T 23-10-2018 A3L12_07960 36c883befd9546719013924917a5fd29 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.831 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L12_05675 e15867efa6d163cf51ea66d613dc1e8d 233 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 219 3.2E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 PIRSF PIRSF005895 1 351 1.3E-153 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 Pfam PF01861 Protein of unknown function DUF43 106 350 6.5E-119 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 Gene3D G3DSA:3.40.50.150 101 326 7.7E-86 T 23-10-2018 A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 Gene3D G3DSA:1.10.10.10 1 83 1.2E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.252 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L12_01265 704f2b2408424207c22294a9a3bccea0 351 SUPERFAMILY SSF53335 167 285 6.86E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 PIRSF PIRSF016210 1 272 1.1E-82 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 Gene3D G3DSA:3.40.630.50 1 186 5.3E-70 T 23-10-2018 A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 Gene3D G3DSA:3.40.50.10700 187 272 3.5E-30 T 23-10-2018 A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 70 269 2.2E-67 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 36.051 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L12_01995 824761afe5a2e6077d9bd5f3695a5177 272 SUPERFAMILY SSF142535 1 270 4.19E-88 T 23-10-2018 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 3.4E-29 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 2.6E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 SUPERFAMILY SSF56553 39 149 1.96E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Gene3D G3DSA:3.30.1360.10 7 251 4.3E-92 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Gene3D G3DSA:2.170.120.12 40 147 4.3E-92 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.909 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 SUPERFAMILY SSF55257 3 257 5.2E-28 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 Gene3D G3DSA:3.30.70.3110 157 218 4.3E-92 T 23-10-2018 A3L12_00770 f34ab9ab81765ef0b7e3928bd177b442 261 SMART SM00662 14 254 1.3E-84 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 Gene3D G3DSA:3.40.50.80 86 195 6.5E-28 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 2.9E-7 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 2.9E-7 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 2.9E-7 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 Gene3D G3DSA:2.40.30.10 3 82 2.5E-11 T 23-10-2018 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.775 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 PIRSF PIRSF006816 1 232 5.3E-75 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 2.2E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 SUPERFAMILY SSF52343 80 228 2.23E-33 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 3.5E-8 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L12_02500 f0483bce658be74fe1c048b3fd1a477a 233 SUPERFAMILY SSF63380 4 85 2.15E-17 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L12_06440 a3833927bcee8ee724549ca78c9909af 226 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 209 1.1E-29 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 A3L12_06440 a3833927bcee8ee724549ca78c9909af 226 Gene3D G3DSA:1.10.10.10 152 224 1.8E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06440 a3833927bcee8ee724549ca78c9909af 226 SUPERFAMILY SSF46785 156 222 1.33E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.253 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 Gene3D G3DSA:3.30.190.20 13 213 8.5E-77 T 23-10-2018 A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 PIRSF PIRSF002155 1 216 1.3E-67 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 SUPERFAMILY SSF56808 5 214 1.31E-64 T 23-10-2018 IPR023674 Ribosomal protein L1-like A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 Gene3D G3DSA:3.40.50.790 59 150 8.5E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 3.3E-48 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A3L12_02020 ee5024e1fbb9fcb9d6fb6ba7d5223f11 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00340 427e897117ac15a33371803f2c21ef15 452 Pfam PF01029 NusB family 10 133 7.8E-20 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A3L12_00340 427e897117ac15a33371803f2c21ef15 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 448 2.8E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L12_00340 427e897117ac15a33371803f2c21ef15 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 2.1E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_00340 427e897117ac15a33371803f2c21ef15 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 2.1E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_00340 427e897117ac15a33371803f2c21ef15 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 2.1E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_00340 427e897117ac15a33371803f2c21ef15 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 2.1E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_00340 427e897117ac15a33371803f2c21ef15 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 2.1E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L12_00340 427e897117ac15a33371803f2c21ef15 452 SUPERFAMILY SSF48013 9 163 9.03E-25 T 23-10-2018 IPR035926 NusB-like superfamily A3L12_00340 427e897117ac15a33371803f2c21ef15 452 Gene3D G3DSA:1.10.940.10 6 151 2.7E-15 T 23-10-2018 IPR035926 NusB-like superfamily A3L12_00340 427e897117ac15a33371803f2c21ef15 452 Gene3D G3DSA:3.40.50.150 154 450 5.3E-79 T 23-10-2018 A3L12_00340 427e897117ac15a33371803f2c21ef15 452 SUPERFAMILY SSF53335 148 450 1.38E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03640 9305874c76972b8adb2c398c7d314020 176 SUPERFAMILY SSF53927 22 146 3.81E-39 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L12_03640 9305874c76972b8adb2c398c7d314020 176 Gene3D G3DSA:3.40.140.10 18 167 1.1E-47 T 23-10-2018 A3L12_03640 9305874c76972b8adb2c398c7d314020 176 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 1.8E-28 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L12_03640 9305874c76972b8adb2c398c7d314020 176 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L12_03640 9305874c76972b8adb2c398c7d314020 176 PIRSF PIRSF006019 12 168 4.4E-56 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 Pfam PF01544 CorA-like Mg2+ transporter protein 35 318 1.5E-70 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 Gene3D G3DSA:1.20.58.340 245 322 1.4E-34 T 23-10-2018 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 Gene3D G3DSA:3.30.460.20 1 132 2.8E-24 T 23-10-2018 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 SUPERFAMILY SSF143865 6 255 3.14E-58 T 23-10-2018 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 7 322 1.1E-83 T 23-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 Gene3D G3DSA:1.20.58.340 133 243 2.2E-29 T 23-10-2018 A3L12_03515 bf00c656bead16496b69a5c5f7a66518 322 SUPERFAMILY SSF144083 257 320 3.53E-23 T 23-10-2018 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 Gene3D G3DSA:1.10.150.20 221 280 5.5E-18 T 23-10-2018 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 SUPERFAMILY SSF88723 8 236 3.92E-64 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 338 143.672 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 2.6E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 2.6E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 2.6E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 2.6E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 2.6E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 SMART SM00279 223 257 8.1E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 SUPERFAMILY SSF47807 221 338 6.43E-30 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 SMART SM00485 1 101 2.1E-47 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 SMART SM00484 140 221 4.0E-37 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 Pfam PF00752 XPG N-terminal domain 12 101 4.2E-21 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 Gene3D G3DSA:3.40.50.1010 1 220 5.3E-85 T 23-10-2018 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 Pfam PF00867 XPG I-region 141 236 1.9E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L12_06570 34bfcbbb59d55d1b844c7264ab3f0c4d 340 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 337 3.1E-154 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A3L12_05640 52a1c5683c0bdc92034a33f628b4e854 377 Gene3D G3DSA:3.40.50.2000 6 357 9.3E-137 T 23-10-2018 A3L12_05640 52a1c5683c0bdc92034a33f628b4e854 377 SUPERFAMILY SSF53756 2 364 1.19E-123 T 23-10-2018 A3L12_05640 52a1c5683c0bdc92034a33f628b4e854 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 361 4.2E-130 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L12_05640 52a1c5683c0bdc92034a33f628b4e854 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 360 3.5E-120 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L12_05640 52a1c5683c0bdc92034a33f628b4e854 377 Gene3D G3DSA:3.40.50.2000 183 347 9.3E-137 T 23-10-2018 A3L12_06410 3b1dda393f821c88078665876ca82d7f 116 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 13 108 1.9E-32 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 A3L12_06410 3b1dda393f821c88078665876ca82d7f 116 Gene3D G3DSA:1.20.120.1610 1 75 2.8E-23 T 23-10-2018 A3L12_06410 3b1dda393f821c88078665876ca82d7f 116 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 14 108 4.6E-26 T 23-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 A3L12_05630 b2430e1d9637f32784de6357fd1de5a0 374 PIRSF PIRSF005357 1 346 2.2E-116 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L12_05630 b2430e1d9637f32784de6357fd1de5a0 374 SUPERFAMILY SSF53756 1 338 5.23E-27 T 23-10-2018 A3L12_05630 b2430e1d9637f32784de6357fd1de5a0 374 Pfam PF04007 Protein of unknown function (DUF354) 1 341 4.4E-96 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 SUPERFAMILY SSF51395 29 360 3.98E-81 T 23-10-2018 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 10 349 1.0E-131 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 SMART SM01240 27 346 0.0038 T 23-10-2018 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 Pfam PF01070 FMN-dependent dehydrogenase 11 343 5.4E-24 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 PIRSF PIRSF003314 4 360 6.0E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 7 350 41.424 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L12_00945 6cf62bd99fc295e1db7bf856001e81b3 371 Gene3D G3DSA:3.20.20.70 7 370 2.7E-127 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_01625 c062257595fa71d680615ca947d5e1c2 238 SUPERFAMILY SSF51695 5 229 1.02E-35 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L12_01625 c062257595fa71d680615ca947d5e1c2 238 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 11 208 2.0E-16 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L12_01625 c062257595fa71d680615ca947d5e1c2 238 Gene3D G3DSA:3.20.20.190 2 235 5.0E-40 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 Pfam PF01769 Divalent cation transporter 54 178 1.8E-23 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 Pfam PF01769 Divalent cation transporter 257 382 4.2E-17 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 Gene3D G3DSA:1.10.357.20 11 184 9.4E-11 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 Gene3D G3DSA:1.10.357.20 210 389 1.7E-15 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 SUPERFAMILY SSF161093 217 388 3.4E-27 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L12_07150 6c76500385dc5921a2ed36d179d6419e 389 SUPERFAMILY SSF161093 13 183 4.84E-32 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L12_05955 3a7f6156a3a31052397caddf605a6ffb 77 SUPERFAMILY SSF89447 1 46 1.67E-14 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L12_05955 3a7f6156a3a31052397caddf605a6ffb 77 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 7.3E-18 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L12_05955 3a7f6156a3a31052397caddf605a6ffb 77 SMART SM00966 4 49 6.8E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L12_05955 3a7f6156a3a31052397caddf605a6ffb 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 47 6.6E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L12_05955 3a7f6156a3a31052397caddf605a6ffb 77 Gene3D G3DSA:2.10.260.10 2 42 7.4E-15 T 23-10-2018 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 2.0E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 Gene3D G3DSA:1.10.10.10 89 174 1.7E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 Gene3D G3DSA:3.30.160.70 1 88 3.1E-16 T 23-10-2018 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 SUPERFAMILY SSF46767 90 169 7.46E-22 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 SUPERFAMILY SSF53155 1 88 7.85E-23 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 1.0E-16 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 6.6E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L12_03985 d3f60c6ba1f41395e32f687c2c55de5a 178 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 5.4E-20 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 PIRSF PIRSF000709 95 212 1.5E-5 T 23-10-2018 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 PIRSF PIRSF000709 2 74 3.5E-4 T 23-10-2018 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 88 5.0E-21 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 95 214 2.1E-16 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 23-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 SUPERFAMILY SSF53254 1 217 2.95E-63 T 23-10-2018 IPR029033 Histidine phosphatase superfamily A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 70 5.2E-25 T 23-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 144 220 5.0E-27 T 23-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 223 40.402 T 23-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 Gene3D G3DSA:3.40.50.1240 1 230 3.3E-71 T 23-10-2018 IPR029033 Histidine phosphatase superfamily A3L12_02275 f5b0d2b48e8bbf9b9dbe38313b65d708 235 SMART SM00855 3 186 5.5E-25 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A3L12_07560 c6a0187c66ab9bbab25c76ae0db42743 397 PIRSF PIRSF017066 1 397 1.5E-116 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L12_07560 c6a0187c66ab9bbab25c76ae0db42743 397 Pfam PF04659 Archaeal flagella protein 277 369 4.8E-29 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L12_07560 c6a0187c66ab9bbab25c76ae0db42743 397 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 280 381 8.0E-48 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 PIRSF PIRSF000412 3 427 9.8E-143 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 Gene3D G3DSA:3.90.1150.10 281 427 5.7E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 Pfam PF00464 Serine hydroxymethyltransferase 12 390 1.5E-78 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 SUPERFAMILY SSF53383 7 425 6.38E-130 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 42.666 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L12_07635 5255e1f22d828b859a494cd177e50d2f 429 Gene3D G3DSA:3.40.640.10 38 280 2.7E-82 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 Gene3D G3DSA:3.40.50.10470 115 310 7.0E-84 T 23-10-2018 A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 Gene3D G3DSA:1.20.120.420 1 114 1.8E-44 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 SUPERFAMILY SSF100950 4 311 8.37E-99 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 1.3E-144 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 Pfam PF01008 Initiation factor 2 subunit family 19 299 2.2E-90 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L12_02280 ac4644e7f39121940883619e3f330b4c 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 3.3E-94 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L12_06200 a0acbeea48ab3d2fabd6f6edb47608c2 493 Pfam PF02386 Cation transport protein 56 479 7.5E-68 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A3L12_06200 a0acbeea48ab3d2fabd6f6edb47608c2 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 97 469 1.7E-108 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A3L12_05720 112566c8aad27a8a6cc3ea7cf3e895f1 316 Gene3D G3DSA:1.10.10.10 1 72 3.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05720 112566c8aad27a8a6cc3ea7cf3e895f1 316 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 60 2.1E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_05720 112566c8aad27a8a6cc3ea7cf3e895f1 316 SUPERFAMILY SSF46785 8 66 1.66E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00425 f8e10f2fda30ed6e07b93a8c4e6bb5c4 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 4.4E-122 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A3L12_00425 f8e10f2fda30ed6e07b93a8c4e6bb5c4 227 Gene3D G3DSA:3.30.420.440 1 227 4.5E-103 T 23-10-2018 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 SUPERFAMILY SSF47323 508 634 1.18E-34 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Pfam PF00750 tRNA synthetases class I (R) 107 356 7.6E-24 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Pfam PF00750 tRNA synthetases class I (R) 380 498 2.3E-11 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 SUPERFAMILY SSF52374 120 504 1.23E-77 T 23-10-2018 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 SMART SM00836 512 634 1.4E-48 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 7.2E-13 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 SUPERFAMILY SSF55190 14 116 8.24E-17 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 SMART SM01016 8 95 1.2E-18 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Pfam PF05746 DALR anticodon binding domain 512 634 1.7E-35 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Gene3D G3DSA:3.40.50.620 122 515 8.9E-157 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 5.3E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 5.3E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 5.3E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 PRINTS PR01038 Arginyl-tRNA synthetase signature 326 347 5.3E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Gene3D G3DSA:3.30.1360.70 5 121 2.7E-28 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 634 27.555 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L12_05615 17285da3a6911ff03f9cc619535dd15b 634 Gene3D G3DSA:1.10.730.10 516 634 5.4E-41 T 23-10-2018 A3L12_03800 3e845e81873ef714dbd609ee632eec50 166 Pfam PF00583 Acetyltransferase (GNAT) family 27 136 1.2E-28 T 23-10-2018 IPR000182 GNAT domain A3L12_03800 3e845e81873ef714dbd609ee632eec50 166 SUPERFAMILY SSF55729 15 157 7.04E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L12_03800 3e845e81873ef714dbd609ee632eec50 166 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 26 155 4.3E-34 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A3L12_03800 3e845e81873ef714dbd609ee632eec50 166 Gene3D G3DSA:3.40.630.30 15 162 2.1E-49 T 23-10-2018 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 SMART SM00382 138 327 1.8E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 SMART SM00278 43 62 0.078 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 SMART SM00278 76 95 110.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 PIRSF PIRSF005856 33 357 9.9E-137 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 42 357 80.16 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 45 357 1.0E-162 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 Pfam PF08423 Rad51 105 357 6.8E-93 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 Pfam PF14520 Helix-hairpin-helix domain 44 98 1.6E-11 T 23-10-2018 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 SUPERFAMILY SSF47794 40 101 3.45E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 Gene3D G3DSA:1.10.150.20 43 106 3.4E-24 T 23-10-2018 A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 SUPERFAMILY SSF52540 119 356 5.35E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04760 639a0a6ea36ab900dafd72a60c3317c8 357 Gene3D G3DSA:3.40.50.300 107 357 6.2E-84 T 23-10-2018 A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 SUPERFAMILY SSF53850 54 385 1.81E-89 T 23-10-2018 A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 PIRSF PIRSF002756 2 387 3.4E-115 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 Gene3D G3DSA:3.40.190.10 135 321 8.0E-107 T 23-10-2018 A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 55 384 3.2E-126 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 Pfam PF12849 PBP superfamily domain 45 355 2.0E-57 T 23-10-2018 IPR024370 PBP domain A3L12_00075 ed82ddc7b88b272d86bad7bf3a2ee242 387 Gene3D G3DSA:3.40.190.10 59 373 8.0E-107 T 23-10-2018 A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.9E-5 T 23-10-2018 A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.9E-5 T 23-10-2018 A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 Gene3D G3DSA:3.50.50.60 4 403 3.9E-137 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 Gene3D G3DSA:3.90.660.50 83 359 3.9E-137 T 23-10-2018 A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 SUPERFAMILY SSF51905 1 392 1.15E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_04145 0ac28af86aef589bd80693781f1c946e 420 Pfam PF01593 Flavin containing amine oxidoreductase 10 243 2.6E-13 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A3L12_06685 db505e60c111965abcdbe778e763d988 140 Pfam PF05763 Protein of unknown function (DUF835) 29 139 3.1E-22 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_01270 109d17b3c9ad8d6e33cf2a87fafd2a68 585 Gene3D G3DSA:1.50.10.20 20 139 4.2E-12 T 23-10-2018 A3L12_01270 109d17b3c9ad8d6e33cf2a87fafd2a68 585 Gene3D G3DSA:1.50.10.20 336 483 2.0E-5 T 23-10-2018 A3L12_01270 109d17b3c9ad8d6e33cf2a87fafd2a68 585 SUPERFAMILY SSF48239 33 483 3.59E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L12_05470 9ef262a86a87093e4ab7b773e879bd57 366 SUPERFAMILY SSF46548 216 338 1.64E-13 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L12_05470 9ef262a86a87093e4ab7b773e879bd57 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_05470 9ef262a86a87093e4ab7b773e879bd57 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_05470 9ef262a86a87093e4ab7b773e879bd57 366 Pfam PF17179 4Fe-4S dicluster domain 232 326 1.3E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 Gene3D G3DSA:3.30.70.20 29 68 7.7E-6 T 23-10-2018 A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 1.0E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 7.1E-12 T 23-10-2018 A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 Gene3D G3DSA:3.30.70.20 69 105 3.3E-10 T 23-10-2018 A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_04020 ba8e88ca44d5b912ac5679d147659f6a 105 SUPERFAMILY SSF54862 34 104 2.26E-25 T 23-10-2018 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 SUPERFAMILY SSF52954 503 604 1.51E-28 T 23-10-2018 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 7.0E-59 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Gene3D G3DSA:3.30.930.10 202 493 2.6E-60 T 23-10-2018 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 483 1.4E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 PRINTS PR01047 Threonyl-tRNA synthetase signature 327 350 1.4E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 PRINTS PR01047 Threonyl-tRNA synthetase signature 427 455 1.4E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 517 1.4E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 PRINTS PR01047 Threonyl-tRNA synthetase signature 293 321 1.4E-31 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Pfam PF03129 Anticodon binding domain 512 599 6.3E-22 T 23-10-2018 IPR004154 Anticodon-binding A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Gene3D G3DSA:3.50.80.10 1 139 3.4E-53 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 31 601 1.3E-167 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 287 491 2.7E-17 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 4.3E-52 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 600 28.672 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 SUPERFAMILY SSF55681 206 488 2.03E-56 T 23-10-2018 A3L12_06145 1832a7270691be3b4eb8e7bfa1cb103f 624 Gene3D G3DSA:3.40.50.800 503 605 2.7E-31 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 PRINTS PR00116 Arginase signature 208 237 4.0E-9 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 PRINTS PR00116 Arginase signature 243 257 4.0E-9 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 PRINTS PR00116 Arginase signature 73 88 4.0E-9 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 Gene3D G3DSA:3.40.800.10 11 285 3.4E-71 T 23-10-2018 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 SUPERFAMILY SSF52768 16 282 9.89E-70 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 TIGRFAM TIGR01230 agmatinase: agmatinase 20 281 6.5E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 PIRSF PIRSF036979 6 285 1.7E-80 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_05920 e5259f0615649bf5f26af67b5b586e1e 285 Pfam PF00491 Arginase family 23 280 2.1E-58 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L12_07375 a852d3b8b9196e4631dbcfd9ba7cf1fc 174 Pfam PF02915 Rubrerythrin 7 147 5.6E-12 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07375 a852d3b8b9196e4631dbcfd9ba7cf1fc 174 Gene3D G3DSA:1.20.1260.10 1 152 1.1E-30 T 23-10-2018 IPR012347 Ferritin-like A3L12_07375 a852d3b8b9196e4631dbcfd9ba7cf1fc 174 SUPERFAMILY SSF47240 5 153 1.15E-21 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 SUPERFAMILY SSF55031 166 264 1.94E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 Pfam PF01546 Peptidase family M20/M25/M40 61 365 1.2E-26 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 Pfam PF07687 Peptidase dimerisation domain 164 264 5.4E-10 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 SUPERFAMILY SSF53187 3 367 1.66E-53 T 23-10-2018 A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 Gene3D G3DSA:3.40.630.10 5 356 1.4E-70 T 23-10-2018 A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 Gene3D G3DSA:3.30.70.360 167 284 1.4E-70 T 23-10-2018 A3L12_03960 03539eaec5cde0dc5fcd303f08d67be2 373 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L12_01235 6c058fabd721d4e60f060478587ee5ad 300 PIRSF PIRSF004944 1 300 3.4E-113 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L12_01235 6c058fabd721d4e60f060478587ee5ad 300 Gene3D G3DSA:3.60.15.10 7 250 1.8E-12 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_01235 6c058fabd721d4e60f060478587ee5ad 300 Hamap MF_01406 UPF0282 protein . 1 286 38.546 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L12_01235 6c058fabd721d4e60f060478587ee5ad 300 SUPERFAMILY SSF56281 1 259 2.36E-13 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 Gene3D G3DSA:1.10.510.10 156 257 8.6E-26 T 23-10-2018 A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 Pfam PF01163 RIO1 family 65 245 2.8E-54 T 23-10-2018 A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 SMART SM00090 23 257 4.8E-114 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 Gene3D G3DSA:3.30.200.20 51 151 1.0E-11 T 23-10-2018 A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 SUPERFAMILY SSF56112 44 249 2.9E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L12_07910 6ad3c144c98e167f43a2e407faa530ce 257 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 SUPERFAMILY SSF46785 297 401 5.99E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Pfam PF13401 AAA domain 58 186 2.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Gene3D G3DSA:3.40.50.300 35 216 3.5E-108 T 23-10-2018 A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 3.0E-149 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 SMART SM00382 57 218 7.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 1.3E-25 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.097 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Gene3D G3DSA:1.10.8.60 19 295 3.5E-108 T 23-10-2018 A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 Gene3D G3DSA:1.10.10.10 304 405 7.4E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 SMART SM01074 312 393 2.9E-34 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L12_04745 f8ec85bca2a581142d0cd6f6087e1760 415 SUPERFAMILY SSF52540 19 291 2.45E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06895 21618f9765e1cafb6e42bc0f41421a52 238 Pfam PF13549 ATP-grasp domain 12 234 7.4E-81 T 23-10-2018 A3L12_06895 21618f9765e1cafb6e42bc0f41421a52 238 Gene3D G3DSA:3.30.1490.20 38 115 1.6E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_06895 21618f9765e1cafb6e42bc0f41421a52 238 SUPERFAMILY SSF56059 19 234 3.89E-45 T 23-10-2018 A3L12_06895 21618f9765e1cafb6e42bc0f41421a52 238 Gene3D G3DSA:3.30.470.20 17 232 1.6E-91 T 23-10-2018 A3L12_06120 e9bfdf0395ab44c2a930fe6f4bc30091 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 4.3E-14 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L12_06120 e9bfdf0395ab44c2a930fe6f4bc30091 268 Gene3D G3DSA:3.20.20.150 1 255 2.8E-26 T 23-10-2018 A3L12_06120 e9bfdf0395ab44c2a930fe6f4bc30091 268 SUPERFAMILY SSF51658 1 239 4.84E-26 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L12_01415 a35f4124514ab6e25a63deb98d143109 118 Gene3D G3DSA:1.20.5.420 5 63 1.7E-23 T 23-10-2018 A3L12_01415 a35f4124514ab6e25a63deb98d143109 118 Gene3D G3DSA:2.20.25.200 64 118 9.0E-25 T 23-10-2018 A3L12_01415 a35f4124514ab6e25a63deb98d143109 118 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 100 9.4E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L12_01415 a35f4124514ab6e25a63deb98d143109 118 PIRSF PIRSF004878 1 116 4.2E-43 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L12_01415 a35f4124514ab6e25a63deb98d143109 118 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 109 26.092 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 SUPERFAMILY SSF55174 9 160 1.03E-31 T 23-10-2018 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 Pfam PF01479 S4 domain 103 148 1.6E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.422 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 SMART SM01390 5 102 3.8E-8 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 1.9E-75 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 Gene3D G3DSA:3.10.290.10 104 173 1.1E-16 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A3L12_00760 cfbf73973686a364a4e9cff9da9e4792 180 SMART SM00363 103 165 3.5E-14 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_04425 e59fbcbe33d1c8a5d7a5a78afec3e893 75 SUPERFAMILY SSF54909 1 74 9.79E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_04425 e59fbcbe33d1c8a5d7a5a78afec3e893 75 Gene3D G3DSA:3.30.70.920 1 74 3.4E-27 T 23-10-2018 A3L12_04425 e59fbcbe33d1c8a5d7a5a78afec3e893 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 1.9E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_06770 b6b4656a281a3418c962e3e8721f2191 162 SUPERFAMILY SSF88723 49 115 3.47E-9 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_06770 b6b4656a281a3418c962e3e8721f2191 162 SMART SM00670 2 100 3.0E-4 T 23-10-2018 IPR002716 PIN domain A3L12_06770 b6b4656a281a3418c962e3e8721f2191 162 Gene3D G3DSA:3.40.50.1010 1 118 9.4E-42 T 23-10-2018 A3L12_06770 b6b4656a281a3418c962e3e8721f2191 162 Pfam PF17146 PIN domain of ribonuclease 5 87 6.9E-20 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A3L12_06770 b6b4656a281a3418c962e3e8721f2191 162 Gene3D G3DSA:2.20.28.10 119 156 1.0E-18 T 23-10-2018 A3L12_00900 de80fc107593005195648c7a4cc3fa6e 533 Gene3D G3DSA:3.80.30.20 213 408 1.6E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L12_00900 de80fc107593005195648c7a4cc3fa6e 533 SUPERFAMILY SSF102114 214 461 5.23E-11 T 23-10-2018 A3L12_00900 de80fc107593005195648c7a4cc3fa6e 533 SMART SM00729 213 446 1.3E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_00900 de80fc107593005195648c7a4cc3fa6e 533 Pfam PF04055 Radical SAM superfamily 217 401 1.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_02925 aa65e99e6b2031210948cacda4c99251 132 Pfam PF01909 Nucleotidyltransferase domain 13 82 1.0E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L12_02925 aa65e99e6b2031210948cacda4c99251 132 SUPERFAMILY SSF81301 4 120 9.58E-16 T 23-10-2018 A3L12_02925 aa65e99e6b2031210948cacda4c99251 132 Gene3D G3DSA:3.30.460.10 1 100 4.3E-17 T 23-10-2018 A3L12_01485 3df1b7d5fb5caf7fe72282e0661f8eb8 336 Gene3D G3DSA:1.10.10.10 3 103 5.1E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01485 3df1b7d5fb5caf7fe72282e0661f8eb8 336 SUPERFAMILY SSF159071 248 335 1.28E-19 T 23-10-2018 A3L12_01485 3df1b7d5fb5caf7fe72282e0661f8eb8 336 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 334 2.2E-49 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L12_01485 3df1b7d5fb5caf7fe72282e0661f8eb8 336 SUPERFAMILY SSF46785 4 99 2.94E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01485 3df1b7d5fb5caf7fe72282e0661f8eb8 336 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 4.5E-22 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_01630 f941e15288e34aca76d6123aa9bb9ac4 248 Gene3D G3DSA:3.20.20.190 1 248 1.9E-88 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L12_01630 f941e15288e34aca76d6123aa9bb9ac4 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 163 3.3E-30 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L12_01630 f941e15288e34aca76d6123aa9bb9ac4 248 SUPERFAMILY SSF51695 7 241 3.29E-58 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 SUPERFAMILY SSF54189 4 77 1.87E-26 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 84 14.536 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 Gene3D G3DSA:3.30.70.330 1 86 6.5E-35 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.009 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 8.2E-37 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00600 e4f4a53ee827c190ec794ebba64e0c73 86 Pfam PF00276 Ribosomal protein L23 5 66 4.9E-19 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L12_06450 0d8d2f958d1bcc7a72d58bf81b39449e 109 SUPERFAMILY SSF50249 8 108 1.91E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_06450 0d8d2f958d1bcc7a72d58bf81b39449e 109 Gene3D G3DSA:2.40.50.140 1 109 6.3E-34 T 23-10-2018 A3L12_06450 0d8d2f958d1bcc7a72d58bf81b39449e 109 Pfam PF01588 Putative tRNA binding domain 14 107 3.1E-25 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L12_08150 5d3eb19a76c8d4d5623e9df5b2ab8770 185 SUPERFAMILY SSF52949 4 180 1.85E-50 T 23-10-2018 A3L12_08150 5d3eb19a76c8d4d5623e9df5b2ab8770 185 SMART SM00506 3 146 4.1E-54 T 23-10-2018 IPR002589 Macro domain A3L12_08150 5d3eb19a76c8d4d5623e9df5b2ab8770 185 Pfam PF01661 Macro domain 20 145 5.1E-34 T 23-10-2018 IPR002589 Macro domain A3L12_08150 5d3eb19a76c8d4d5623e9df5b2ab8770 185 Gene3D G3DSA:3.40.220.10 3 181 8.2E-55 T 23-10-2018 A3L12_03695 d141149a54a6b7fa94fd9c3099103e98 304 Pfam PF01895 PhoU domain 138 230 3.2E-14 T 23-10-2018 IPR026022 PhoU domain A3L12_03695 d141149a54a6b7fa94fd9c3099103e98 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 6.1E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L12_03695 d141149a54a6b7fa94fd9c3099103e98 304 Gene3D G3DSA:1.20.58.220 134 236 4.3E-12 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_03695 d141149a54a6b7fa94fd9c3099103e98 304 SUPERFAMILY SSF109755 125 304 4.84E-18 T 23-10-2018 A3L12_03695 d141149a54a6b7fa94fd9c3099103e98 304 SMART SM00966 8 54 7.8E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L12_04460 39cc7e9d8cacb79ee77faf12dd277323 166 Pfam PF01899 Na+/H+ ion antiporter subunit 7 162 8.3E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_04460 39cc7e9d8cacb79ee77faf12dd277323 166 PIRSF PIRSF019239 1 163 7.5E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 Pfam PF05690 Thiazole biosynthesis protein ThiG 174 216 1.9E-5 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 SUPERFAMILY SSF51351 6 223 2.09E-46 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 Gene3D G3DSA:3.20.20.70 1 225 3.8E-92 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 Pfam PF00121 Triosephosphate isomerase 8 124 2.3E-9 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.713 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A3L12_04720 0e37b99de625fa5e4dba95a64e63efe3 228 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 3.3E-60 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 293 315 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 Gene3D G3DSA:3.90.550.10 3 218 2.0E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 Pfam PF12804 MobA-like NTP transferase domain 6 107 8.4E-15 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 SUPERFAMILY SSF53448 5 220 3.6E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 Gene3D G3DSA:1.20.120.1760 228 420 4.4E-54 T 23-10-2018 A3L12_02080 33adf1574b47eda57f8d1f08fc2d7330 426 Pfam PF01066 CDP-alcohol phosphatidyltransferase 253 315 7.6E-7 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 Gene3D G3DSA:3.30.70.140 1 97 1.9E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 94 1.2E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 148 33.978 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 96 1.0E-30 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 Gene3D G3DSA:2.30.30.20 98 150 1.3E-22 T 23-10-2018 A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 SUPERFAMILY SSF54893 2 97 5.1E-35 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 99 146 3.5E-18 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 SUPERFAMILY SSF57825 99 147 1.44E-15 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A3L12_03875 4f19df7a1fb3ebe5ced233fb7887ce97 150 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 147 5.4E-61 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L12_02775 157becc242db86e99fa5bf3dbe4b867f 144 Gene3D G3DSA:1.20.1260.10 1 144 7.0E-12 T 23-10-2018 IPR012347 Ferritin-like A3L12_02775 157becc242db86e99fa5bf3dbe4b867f 144 SUPERFAMILY SSF47240 2 142 9.12E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 4.9E-85 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.095 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 1.3E-81 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 SUPERFAMILY SSF64005 31 259 5.49E-87 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L12_06160 6f99284bce3f277bc5b340e08ec73e15 264 Gene3D G3DSA:3.40.1180.10 19 264 1.3E-101 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 3.8E-12 T 23-10-2018 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 3.8E-12 T 23-10-2018 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 3.8E-12 T 23-10-2018 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 3.8E-12 T 23-10-2018 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 SMART SM00998 360 439 1.0E-30 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 Gene3D G3DSA:1.10.275.10 1 100 5.6E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 Gene3D G3DSA:1.10.40.30 360 448 3.6E-22 T 23-10-2018 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 Pfam PF00206 Lyase 13 295 1.3E-57 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 1.2E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 1.2E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 1.2E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 1.2E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 SUPERFAMILY SSF48557 4 443 3.14E-137 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 2.3E-18 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 4.3E-187 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L12_07195 264b52c219b8d25712c87b849fa0ab23 451 Gene3D G3DSA:1.20.200.10 101 359 9.1E-99 T 23-10-2018 A3L12_02585 13d34b890946ede4dda912da4153ec91 263 SUPERFAMILY SSF52540 21 258 1.1E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02585 13d34b890946ede4dda912da4153ec91 263 Pfam PF06745 KaiC 24 260 2.0E-76 T 23-10-2018 IPR014774 KaiC-like domain A3L12_02585 13d34b890946ede4dda912da4153ec91 263 Gene3D G3DSA:3.40.50.300 17 263 1.4E-72 T 23-10-2018 A3L12_00790 84ab926fe643414f17902084d965f152 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 5.3E-60 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00790 84ab926fe643414f17902084d965f152 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A3L12_00790 84ab926fe643414f17902084d965f152 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 36.65 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00790 84ab926fe643414f17902084d965f152 135 Gene3D G3DSA:3.30.230.10 1 135 2.5E-50 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_00790 84ab926fe643414f17902084d965f152 135 SUPERFAMILY SSF54211 3 135 1.67E-33 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_00790 84ab926fe643414f17902084d965f152 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 2.3E-29 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 SUPERFAMILY SSF54849 149 405 8.24E-30 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 3.4E-240 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 3.1E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 3.1E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 3.1E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 3.1E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 3.1E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 Gene3D G3DSA:1.10.560.10 28 522 3.1E-213 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.1E-184 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 SUPERFAMILY SSF48592 17 524 3.55E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 Gene3D G3DSA:3.30.260.10 147 405 3.1E-213 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 SUPERFAMILY SSF52029 212 378 1.84E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 Gene3D G3DSA:3.50.7.10 218 369 3.1E-213 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L12_03015 a1962882f5c709d120e95617e8cdf66d 546 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L12_00025 a373e02d89fe1a0144bb29296487f018 191 Gene3D G3DSA:1.10.10.10 1 89 4.7E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_00025 a373e02d89fe1a0144bb29296487f018 191 Pfam PF12840 Helix-turn-helix domain 11 67 6.2E-14 T 23-10-2018 A3L12_00025 a373e02d89fe1a0144bb29296487f018 191 SMART SM00418 11 105 6.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_00025 a373e02d89fe1a0144bb29296487f018 191 Gene3D G3DSA:1.10.20.10 90 191 1.5E-48 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_00025 a373e02d89fe1a0144bb29296487f018 191 SUPERFAMILY SSF46785 1 165 1.06E-32 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04495 4289d372678d920050aaea4c2170401a 509 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 70 117 1.3E-10 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04495 4289d372678d920050aaea4c2170401a 509 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 1.7E-15 T 23-10-2018 A3L12_04495 4289d372678d920050aaea4c2170401a 509 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 1.7E-15 T 23-10-2018 A3L12_04495 4289d372678d920050aaea4c2170401a 509 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 1.7E-15 T 23-10-2018 A3L12_04495 4289d372678d920050aaea4c2170401a 509 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 1.7E-15 T 23-10-2018 A3L12_04495 4289d372678d920050aaea4c2170401a 509 Pfam PF00361 Proton-conducting membrane transporter 132 432 2.4E-65 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 Gene3D G3DSA:2.10.260.30 1 69 3.8E-27 T 23-10-2018 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 SUPERFAMILY SSF46906 66 138 8.77E-22 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 SUPERFAMILY SSF54747 3 82 9.68E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 2.6E-21 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 27.99 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 SMART SM00649 5 138 9.2E-63 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 3.5E-22 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A3L12_02015 af7ccc056cbab6f04db1c437c30c18b4 162 Gene3D G3DSA:1.10.10.250 73 162 3.1E-34 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L12_04205 3a8b185e359f2ab3d239c9d0110903e4 96 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 90 1.4E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A3L12_05035 f4fcda3402fd3dc872a34ba5429bfcb8 75 Pfam PF04023 FeoA domain 3 73 3.2E-17 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L12_05035 f4fcda3402fd3dc872a34ba5429bfcb8 75 SMART SM00899 3 74 2.6E-18 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L12_05035 f4fcda3402fd3dc872a34ba5429bfcb8 75 Gene3D G3DSA:2.30.30.90 12 75 1.2E-17 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A3L12_05035 f4fcda3402fd3dc872a34ba5429bfcb8 75 SUPERFAMILY SSF50037 5 74 5.95E-15 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L12_01200 b7278d5dbdfae68d9943f9adf045b615 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 2.6E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_01200 b7278d5dbdfae68d9943f9adf045b615 80 Gene3D G3DSA:3.30.70.920 1 73 8.7E-22 T 23-10-2018 A3L12_01200 b7278d5dbdfae68d9943f9adf045b615 80 SUPERFAMILY SSF54909 1 76 9.39E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Gene3D G3DSA:3.40.120.10 166 345 2.3E-53 T 23-10-2018 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 2.5E-20 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 1.5E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 1.9E-18 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 394 440 1.2E-6 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.773 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Gene3D G3DSA:3.40.120.10 1 147 6.2E-51 T 23-10-2018 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Gene3D G3DSA:3.40.120.10 247 330 2.3E-53 T 23-10-2018 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 SUPERFAMILY SSF53738 2 140 5.1E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 SUPERFAMILY SSF53738 150 249 7.85E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 SUPERFAMILY SSF53738 252 355 6.67E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 SUPERFAMILY SSF55957 348 447 3.92E-22 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 1.2E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 Gene3D G3DSA:3.30.310.50 360 446 6.9E-20 T 23-10-2018 A3L12_03900 35795a351454d85f91fc7c5660a6b155 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 1.5E-161 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_04240 5da310cdaaf0f03a07880678f06442c2 181 Pfam PF00156 Phosphoribosyl transferase domain 38 164 2.3E-22 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L12_04240 5da310cdaaf0f03a07880678f06442c2 181 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 171 1.1E-49 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_04240 5da310cdaaf0f03a07880678f06442c2 181 SUPERFAMILY SSF53271 6 160 1.44E-46 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L12_04240 5da310cdaaf0f03a07880678f06442c2 181 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 181 27.462 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_04240 5da310cdaaf0f03a07880678f06442c2 181 Gene3D G3DSA:3.40.50.2020 1 178 2.3E-59 T 23-10-2018 A3L12_07975 6623828db71cc3a2c4b8480000a61935 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 92 1.6E-26 T 23-10-2018 IPR002767 Thiamine-binding protein A3L12_07975 6623828db71cc3a2c4b8480000a61935 93 Pfam PF01910 Thiamine-binding protein 4 92 6.5E-30 T 23-10-2018 IPR002767 Thiamine-binding protein A3L12_07975 6623828db71cc3a2c4b8480000a61935 93 Gene3D G3DSA:3.30.70.930 1 93 1.9E-32 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L12_07975 6623828db71cc3a2c4b8480000a61935 93 SUPERFAMILY SSF89957 1 92 7.72E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L12_06005 b6bd4682f0fd00a67c634d508c9b1b15 179 Gene3D G3DSA:1.20.1260.10 19 174 4.0E-25 T 23-10-2018 IPR012347 Ferritin-like A3L12_06005 b6bd4682f0fd00a67c634d508c9b1b15 179 Pfam PF02915 Rubrerythrin 120 178 3.1E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_06005 b6bd4682f0fd00a67c634d508c9b1b15 179 SUPERFAMILY SSF47240 27 175 3.45E-17 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_02680 32514524a07b3d1352d2ef29a20110e5 332 Gene3D G3DSA:1.20.1530.20 12 318 6.9E-49 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_02680 32514524a07b3d1352d2ef29a20110e5 332 Pfam PF01758 Sodium Bile acid symporter family 48 230 2.4E-37 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 280 471 8.6E-8 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 Pfam PF00149 Calcineurin-like phosphoesterase 1 184 2.2E-19 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 SUPERFAMILY SSF56300 1 239 4.22E-51 T 23-10-2018 A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 SUPERFAMILY SSF56300 257 483 3.23E-29 T 23-10-2018 A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 Gene3D G3DSA:3.60.21.10 1 250 2.0E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_07805 8786bfa1c969a9d17934a67b825a1b1b 503 Gene3D G3DSA:3.60.21.10 251 490 6.1E-19 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_07320 426810898b9a41ab8726aacd0b8526c5 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 2.1E-36 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_07320 426810898b9a41ab8726aacd0b8526c5 281 Gene3D G3DSA:3.20.20.70 2 279 2.0E-83 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_07320 426810898b9a41ab8726aacd0b8526c5 281 SMART SM01133 23 251 9.8E-41 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_07320 426810898b9a41ab8726aacd0b8526c5 281 SUPERFAMILY SSF51569 8 266 6.59E-68 T 23-10-2018 A3L12_07320 426810898b9a41ab8726aacd0b8526c5 281 PIRSF PIRSF038992 4 280 5.0E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L12_05085 1cec931d6b8b74f2e8a5e4ed4e46cf0d 76 SUPERFAMILY SSF50182 3 73 4.28E-17 T 23-10-2018 IPR010920 LSM domain superfamily A3L12_05085 1cec931d6b8b74f2e8a5e4ed4e46cf0d 76 Pfam PF01423 LSM domain 9 72 6.7E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L12_05085 1cec931d6b8b74f2e8a5e4ed4e46cf0d 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.12 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A3L12_05085 1cec931d6b8b74f2e8a5e4ed4e46cf0d 76 Gene3D G3DSA:2.30.30.100 1 74 5.0E-22 T 23-10-2018 A3L12_05085 1cec931d6b8b74f2e8a5e4ed4e46cf0d 76 SMART SM00651 7 72 3.5E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L12_06340 5a631b61fecb3751ed29ae075dbde211 70 Gene3D G3DSA:1.10.10.10 1 69 6.9E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06340 5a631b61fecb3751ed29ae075dbde211 70 Pfam PF01022 Bacterial regulatory protein, arsR family 4 44 1.2E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_06340 5a631b61fecb3751ed29ae075dbde211 70 SUPERFAMILY SSF46785 4 61 3.69E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 Gene3D G3DSA:3.30.470.20 122 379 5.9E-92 T 23-10-2018 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 SUPERFAMILY SSF56059 139 380 5.14E-76 T 23-10-2018 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 Gene3D G3DSA:3.30.1490.20 152 218 5.9E-92 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 Gene3D G3DSA:3.40.50.20 1 121 1.1E-40 T 23-10-2018 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 1.3E-79 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 PIRSF PIRSF004602 1 380 6.8E-141 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 SUPERFAMILY SSF52440 1 133 9.11E-40 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L12_03145 00daea60cb3ed0c27536e92136bc144c 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 154 1.1E-41 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L12_07825 e657c54467a5a2847a912826fcf510d6 291 Pfam PF00753 Metallo-beta-lactamase superfamily 16 189 2.8E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_07825 e657c54467a5a2847a912826fcf510d6 291 SMART SM00849 15 200 3.8E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_07825 e657c54467a5a2847a912826fcf510d6 291 Gene3D G3DSA:3.60.15.10 10 224 9.7E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_07825 e657c54467a5a2847a912826fcf510d6 291 SUPERFAMILY SSF56281 10 277 2.24E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 SUPERFAMILY SSF64182 162 453 3.01E-55 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 SUPERFAMILY SSF51735 1 138 2.06E-16 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 Pfam PF02254 TrkA-N domain 3 94 1.5E-15 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 Pfam PF01368 DHH family 165 315 3.0E-9 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 Gene3D G3DSA:3.40.50.720 1 140 2.0E-17 T 23-10-2018 A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 Pfam PF02272 DHHA1 domain 356 474 2.7E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L12_05445 69d050cf49e4c9871e72484358abc1f1 487 Gene3D G3DSA:3.90.1640.10 163 351 8.5E-27 T 23-10-2018 A3L12_04790 54ce3ddba1658a304a58e93c73e52286 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 149 8.7E-43 T 23-10-2018 IPR002178 PTS EIIA type-2 domain A3L12_04790 54ce3ddba1658a304a58e93c73e52286 153 Gene3D G3DSA:3.40.930.10 1 150 8.9E-50 T 23-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A3L12_04790 54ce3ddba1658a304a58e93c73e52286 153 SUPERFAMILY SSF55804 5 149 1.05E-42 T 23-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 A3L12_04790 54ce3ddba1658a304a58e93c73e52286 153 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 53 69 - T 23-10-2018 IPR002178 PTS EIIA type-2 domain A3L12_04790 54ce3ddba1658a304a58e93c73e52286 153 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 8 134 1.2E-41 T 23-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A3L12_05350 1dea849adcb662ad25e129e3cd027261 115 PIRSF PIRSF006113 1 115 3.0E-34 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L12_05350 1dea849adcb662ad25e129e3cd027261 115 Gene3D G3DSA:3.30.479.10 1 115 4.2E-39 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L12_05350 1dea849adcb662ad25e129e3cd027261 115 SUPERFAMILY SSF55620 1 113 4.23E-32 T 23-10-2018 A3L12_05350 1dea849adcb662ad25e129e3cd027261 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 6.4E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L12_01765 527be4db81c776d89cadb1d1020ea7a8 67 SUPERFAMILY SSF54285 5 67 5.38E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L12_01765 527be4db81c776d89cadb1d1020ea7a8 67 Gene3D G3DSA:3.10.20.30 1 67 1.2E-23 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_01765 527be4db81c776d89cadb1d1020ea7a8 67 Pfam PF02597 ThiS family 12 67 2.8E-8 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L12_03630 3e156a51d012db8b692a4a078998e3a8 121 SUPERFAMILY SSF46785 17 116 3.66E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_03630 3e156a51d012db8b692a4a078998e3a8 121 Pfam PF03965 Penicillinase repressor 19 111 1.1E-15 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A3L12_03630 3e156a51d012db8b692a4a078998e3a8 121 Gene3D G3DSA:1.10.10.10 19 85 3.5E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 SUPERFAMILY SSF100950 2 149 1.85E-45 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 Gene3D G3DSA:3.40.50.1360 5 221 9.7E-88 T 23-10-2018 A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 Gene3D G3DSA:3.30.70.260 127 205 9.7E-88 T 23-10-2018 A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 35.732 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 1.0E-80 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 SUPERFAMILY SSF75445 131 207 1.05E-23 T 23-10-2018 A3L12_01075 424f7181af699d12364f6836f8ca21ea 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 5.2E-64 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Gene3D G3DSA:3.90.228.20 247 604 2.2E-147 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Gene3D G3DSA:3.40.449.10 27 246 2.2E-147 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 SUPERFAMILY SSF53795 244 605 4.58E-108 T 23-10-2018 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Gene3D G3DSA:2.170.8.10 65 398 2.2E-147 T 23-10-2018 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 29 239 3.6E-58 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 PIRSF PIRSF001348 6 609 5.2E-207 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 605 9.0E-107 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 SUPERFAMILY SSF68923 13 243 1.78E-60 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L12_07200 700f6d68a61d274b1450b3dfeb7e1ad6 621 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 606 36.301 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 5.1E-84 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 Gene3D G3DSA:1.10.599.10 240 601 8.8E-162 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 Gene3D G3DSA:3.60.9.10 1 211 3.7E-97 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 SUPERFAMILY SSF48310 211 604 1.57E-148 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 Gene3D G3DSA:1.10.569.10 242 427 8.8E-162 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 SMART SM00790 4 207 2.5E-133 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 225 601 1.2E-146 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L12_07450 dea3a4a704db69dcff45a27850e81ce2 605 SUPERFAMILY SSF56228 1 209 1.44E-80 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L12_06755 860de7cabbc8f9cc094957a175a45600 276 SUPERFAMILY SSF48150 89 266 5.18E-31 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L12_06755 860de7cabbc8f9cc094957a175a45600 276 Gene3D G3DSA:1.10.1670.10 215 272 6.4E-7 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L12_06755 860de7cabbc8f9cc094957a175a45600 276 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 105 248 8.5E-10 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L12_06755 860de7cabbc8f9cc094957a175a45600 276 Gene3D G3DSA:1.10.340.30 98 214 3.0E-21 T 23-10-2018 A3L12_06755 860de7cabbc8f9cc094957a175a45600 276 SMART SM00478 109 267 5.7E-16 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 295 3.4E-81 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 SUPERFAMILY SSF51735 1 150 2.55E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 Gene3D G3DSA:3.40.50.720 1 171 1.9E-64 T 23-10-2018 A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 Gene3D G3DSA:1.10.1040.10 172 296 4.8E-41 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 8.2E-37 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 173 295 6.8E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A3L12_03980 aa75d1b655a54cbabea1bf5bad5338e9 306 SUPERFAMILY SSF48179 173 295 9.52E-28 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L12_08100 33fa92b453c3b75427234a486267250b 223 Pfam PF00005 ABC transporter 21 155 3.6E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_08100 33fa92b453c3b75427234a486267250b 223 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_08100 33fa92b453c3b75427234a486267250b 223 SMART SM00382 25 203 9.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_08100 33fa92b453c3b75427234a486267250b 223 Gene3D G3DSA:3.40.50.300 1 218 2.3E-45 T 23-10-2018 A3L12_08100 33fa92b453c3b75427234a486267250b 223 SUPERFAMILY SSF52540 2 214 3.34E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 SUPERFAMILY SSF52540 227 552 1.16E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 Gene3D G3DSA:3.40.50.300 201 402 2.8E-49 T 23-10-2018 A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 SMART SM00490 453 538 2.7E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 Pfam PF00270 DEAD/DEAH box helicase 219 382 2.1E-22 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 Pfam PF00271 Helicase conserved C-terminal domain 436 536 5.5E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 SMART SM00487 213 410 4.0E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L12_06975 473ac688d9f2ecf7f4fc126722e0ee8a 831 Gene3D G3DSA:3.40.50.300 404 580 3.0E-28 T 23-10-2018 A3L12_02425 7d7f48e8a25f8a3c008a0d06dcff415e 298 Gene3D G3DSA:1.20.1640.10 113 297 1.5E-13 T 23-10-2018 A3L12_02425 7d7f48e8a25f8a3c008a0d06dcff415e 298 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 25 297 25.667 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A3L12_02425 7d7f48e8a25f8a3c008a0d06dcff415e 298 Pfam PF02355 Protein export membrane protein 118 293 8.9E-30 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L12_02425 7d7f48e8a25f8a3c008a0d06dcff415e 298 SUPERFAMILY SSF82866 121 288 1.57E-23 T 23-10-2018 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 SUPERFAMILY SSF51735 97 281 1.06E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 Gene3D G3DSA:3.40.50.720 92 282 1.6E-133 T 23-10-2018 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 SUPERFAMILY SSF52283 1 133 1.85E-38 T 23-10-2018 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 4.6E-72 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 Gene3D G3DSA:3.40.50.720 7 298 1.6E-133 T 23-10-2018 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 6.4E-38 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L12_03970 facdb3804a9ac34ac0dfb1e23148026f 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L12_07400 a153f7454e4d212d0bb2db379c21c6c0 172 Pfam PF02915 Rubrerythrin 20 155 3.6E-32 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07400 a153f7454e4d212d0bb2db379c21c6c0 172 SUPERFAMILY SSF47240 13 163 9.21E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_07400 a153f7454e4d212d0bb2db379c21c6c0 172 Gene3D G3DSA:1.20.1260.10 10 159 1.6E-47 T 23-10-2018 IPR012347 Ferritin-like A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 Pfam PF01866 Putative diphthamide synthesis protein 26 320 6.9E-76 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 Gene3D G3DSA:3.40.50.11840 5 98 8.4E-31 T 23-10-2018 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 Gene3D G3DSA:3.40.50.11860 212 313 5.9E-35 T 23-10-2018 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 Gene3D G3DSA:3.40.50.11850 101 208 1.9E-38 T 23-10-2018 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 4.3E-112 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 8 313 3.6E-90 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_03375 3ca43ff0bff8c272b532195c7b3451ff 341 PIRSF PIRSF004967 2 333 1.8E-80 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Pfam PF03465 eRF1 domain 3 261 356 1.2E-24 T 23-10-2018 IPR005142 eRF1 domain 3 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Gene3D G3DSA:2.30.30.870 1 130 2.1E-39 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 SUPERFAMILY SSF53137 131 255 5.23E-29 T 23-10-2018 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 1.9E-107 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 SMART SM01194 1 129 3.7E-47 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Pfam PF03463 eRF1 domain 1 6 127 4.5E-30 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Gene3D G3DSA:3.30.1330.30 259 357 2.1E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 SUPERFAMILY SSF159065 2 128 5.36E-36 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Pfam PF03464 eRF1 domain 2 136 252 1.0E-13 T 23-10-2018 IPR005141 eRF1 domain 2 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 SUPERFAMILY SSF55315 251 356 1.94E-28 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Gene3D G3DSA:3.30.420.60 134 258 1.4E-33 T 23-10-2018 A3L12_05050 dcaaf8ea12b6461e526b6f1f3d576c69 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.039 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A3L12_00565 3c37e082baf490aa1e61534f1317f0ed 193 SUPERFAMILY SSF52540 8 126 1.83E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00565 3c37e082baf490aa1e61534f1317f0ed 193 Gene3D G3DSA:3.40.50.300 3 167 6.8E-14 T 23-10-2018 A3L12_00565 3c37e082baf490aa1e61534f1317f0ed 193 Pfam PF00437 Type II/IV secretion system protein 7 111 5.7E-7 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 SUPERFAMILY SSF52540 1 110 4.09E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 Gene3D G3DSA:3.20.20.20 158 221 3.9E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 117 1.4E-22 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 Pfam PF04060 Putative Fe-S cluster 160 190 6.2E-9 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 Gene3D G3DSA:3.40.50.300 1 157 4.9E-27 T 23-10-2018 A3L12_06485 30fe75d5b35977cbf7ab1605fb5984b2 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 110 1.5E-17 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 Pfam PF02803 Thiolase, C-terminal domain 260 355 3.3E-10 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 Gene3D G3DSA:3.40.47.10 4 385 5.1E-121 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 PIRSF PIRSF000429 1 384 7.8E-63 T 23-10-2018 IPR002155 Thiolase GO:0016747 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 SUPERFAMILY SSF53901 233 383 3.49E-28 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 SUPERFAMILY SSF53901 4 229 1.78E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L12_02250 7b63ced82bb0d911cee483f17958ae9f 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 9.1E-23 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A3L12_05705 0e135d64c10312da6a58cf87b182127c 171 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 82 123 6.0E-10 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05705 0e135d64c10312da6a58cf87b182127c 171 Gene3D G3DSA:3.30.460.80 1 126 2.6E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05705 0e135d64c10312da6a58cf87b182127c 171 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 151 6.4E-25 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05705 0e135d64c10312da6a58cf87b182127c 171 SUPERFAMILY SSF143243 23 159 3.01E-29 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_02855 fba6cc2aedf3da4a9e8899578f636ab0 474 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 31 380 4.9E-24 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L12_02855 fba6cc2aedf3da4a9e8899578f636ab0 474 Gene3D G3DSA:3.40.720.10 1 279 5.1E-32 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_02855 fba6cc2aedf3da4a9e8899578f636ab0 474 SUPERFAMILY SSF53649 3 417 4.07E-36 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_02855 fba6cc2aedf3da4a9e8899578f636ab0 474 Gene3D G3DSA:3.40.720.10 359 448 9.3E-11 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_02225 dafeee3051dc0efbb90e1b98c2d1a09e 131 PIRSF PIRSF006606 3 129 8.9E-45 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L12_02225 dafeee3051dc0efbb90e1b98c2d1a09e 131 Pfam PF04009 Protein of unknown function (DUF356) 5 110 1.7E-34 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L12_02935 c9f9ceec7f153fce3c4b67a5cb3abc9c 365 Gene3D G3DSA:3.40.640.10 1 238 1.1E-108 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_02935 c9f9ceec7f153fce3c4b67a5cb3abc9c 365 PIRSF PIRSF000390 1 364 5.9E-131 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L12_02935 c9f9ceec7f153fce3c4b67a5cb3abc9c 365 SUPERFAMILY SSF53383 2 362 2.69E-132 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_02935 c9f9ceec7f153fce3c4b67a5cb3abc9c 365 Gene3D G3DSA:3.90.1150.10 239 363 3.8E-40 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_02935 c9f9ceec7f153fce3c4b67a5cb3abc9c 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 359 7.1E-140 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 94.549 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 Pfam PF00709 Adenylosuccinate synthetase 150 289 6.4E-41 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 Pfam PF00709 Adenylosuccinate synthetase 294 333 3.4E-5 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 Pfam PF00709 Adenylosuccinate synthetase 5 146 3.1E-36 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 SMART SM00788 3 334 6.4E-142 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 Gene3D G3DSA:3.40.440.10 1 339 7.1E-133 T 23-10-2018 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L12_07305 171ecbe2f16f615f98b28f6bdb0e874b 339 SUPERFAMILY SSF52540 2 335 6.27E-103 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04735 d3ceee9e0782f8a2ab96ee345b070262 1271 Pfam PF03833 DNA polymerase II large subunit DP2 11 950 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_04735 d3ceee9e0782f8a2ab96ee345b070262 1271 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1215 513.943 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_04735 d3ceee9e0782f8a2ab96ee345b070262 1271 PIRSF PIRSF016275 1 1201 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_04735 d3ceee9e0782f8a2ab96ee345b070262 1271 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 7 1195 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L12_02485 683c594882546580190eee7d47f41953 411 Pfam PF01411 tRNA synthetases class II (A) 20 94 1.2E-10 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_02485 683c594882546580190eee7d47f41953 411 Pfam PF02272 DHHA1 domain 270 405 7.3E-16 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L12_02485 683c594882546580190eee7d47f41953 411 Gene3D G3DSA:3.10.310.40 302 407 6.3E-10 T 23-10-2018 A3L12_02485 683c594882546580190eee7d47f41953 411 Gene3D G3DSA:2.40.30.130 1 91 4.3E-19 T 23-10-2018 A3L12_02485 683c594882546580190eee7d47f41953 411 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 7.0E-9 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_02485 683c594882546580190eee7d47f41953 411 Gene3D G3DSA:3.30.980.10 92 247 8.6E-41 T 23-10-2018 A3L12_02485 683c594882546580190eee7d47f41953 411 SUPERFAMILY SSF50447 1 89 1.31E-14 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_02485 683c594882546580190eee7d47f41953 411 SUPERFAMILY SSF55186 95 241 2.09E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L12_02485 683c594882546580190eee7d47f41953 411 SMART SM00863 191 234 1.5E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_07575 076c1bb080fafa3d5b2c8aa9a765ef26 320 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 8 31 2.9E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L12_07575 076c1bb080fafa3d5b2c8aa9a765ef26 320 Pfam PF01917 Archaebacterial flagellin 10 134 1.3E-35 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L12_07575 076c1bb080fafa3d5b2c8aa9a765ef26 320 Pfam PF01917 Archaebacterial flagellin 206 306 1.6E-10 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 SUPERFAMILY SSF51905 2 291 1.01E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.3E-10 T 23-10-2018 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.3E-10 T 23-10-2018 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.3E-10 T 23-10-2018 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 Pfam PF01494 FAD binding domain 2 162 9.1E-12 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 8.7E-50 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L12_00170 bbdd2e0e72c5c6efdb12ddd178ace365 370 Gene3D G3DSA:3.50.50.60 1 367 6.5E-54 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02040 fe6cc20360f123e7bb05a65ce5982c4c 162 Gene3D G3DSA:2.70.40.10 1 154 3.7E-41 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L12_02040 fe6cc20360f123e7bb05a65ce5982c4c 162 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 26.33 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L12_02040 fe6cc20360f123e7bb05a65ce5982c4c 162 SUPERFAMILY SSF51283 1 152 2.09E-37 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L12_02040 fe6cc20360f123e7bb05a65ce5982c4c 162 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 8.5E-42 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L12_02040 fe6cc20360f123e7bb05a65ce5982c4c 162 Pfam PF00692 dUTPase 42 139 6.4E-13 T 23-10-2018 IPR029054 dUTPase-like A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 Gene3D G3DSA:1.20.1250.20 3 381 1.0E-49 T 23-10-2018 A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 Pfam PF07690 Major Facilitator Superfamily 13 347 6.2E-42 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 PRINTS PR01035 Tetracycline resistance protein signature 135 157 2.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 PRINTS PR01035 Tetracycline resistance protein signature 299 319 2.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L12_03685 84b2a11229a3077ce9a94dd881e2885d 393 SUPERFAMILY SSF103473 6 380 9.68E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_07660 cf564c6c1e83e257480fdf862d3950e9 191 SMART SM01022 10 111 2.8E-15 T 23-10-2018 IPR007374 ASCH domain A3L12_07660 cf564c6c1e83e257480fdf862d3950e9 191 Pfam PF04266 ASCH domain 14 110 3.0E-18 T 23-10-2018 IPR007374 ASCH domain A3L12_07660 cf564c6c1e83e257480fdf862d3950e9 191 SUPERFAMILY SSF88697 7 109 1.99E-18 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_02350 3861431eeb5ae2a8af1cf8ca76443191 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 8.2E-76 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L12_02350 3861431eeb5ae2a8af1cf8ca76443191 538 Gene3D G3DSA:1.20.1730.10 22 519 1.2E-90 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L12_02350 3861431eeb5ae2a8af1cf8ca76443191 538 Pfam PF00474 Sodium:solute symporter family 33 435 3.4E-81 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L12_01820 78c65cc6a596303501bd2c03dcc95786 393 Gene3D G3DSA:3.90.550.10 1 393 9.7E-158 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01820 78c65cc6a596303501bd2c03dcc95786 393 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 381 2.2E-178 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L12_01820 78c65cc6a596303501bd2c03dcc95786 393 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 380 3.9E-156 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L12_01820 78c65cc6a596303501bd2c03dcc95786 393 SUPERFAMILY SSF53448 53 176 1.04E-5 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_02710 61d18b6a4bb1dfbc39b51d79764f3f66 145 Gene3D G3DSA:3.30.300.20 3 144 5.4E-42 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_02710 61d18b6a4bb1dfbc39b51d79764f3f66 145 Pfam PF02566 OsmC-like protein 37 140 2.7E-23 T 23-10-2018 IPR003718 OsmC/Ohr family A3L12_02710 61d18b6a4bb1dfbc39b51d79764f3f66 145 SUPERFAMILY SSF82784 6 142 3.27E-40 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L12_00065 253e0756e5d55003c26ab01381990eab 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 290 5.5E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_00065 253e0756e5d55003c26ab01381990eab 305 Gene3D G3DSA:1.10.3720.10 58 302 5.5E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00065 253e0756e5d55003c26ab01381990eab 305 SUPERFAMILY SSF161098 12 290 2.06E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00065 253e0756e5d55003c26ab01381990eab 305 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 6 298 1.6E-87 T 23-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A3L12_04475 832263bec95266bf7ad8ed08588c1b04 88 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 1.2E-16 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L12_05215 54766ee8ca58d8b21ca3a89cff70d639 359 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 255 1.3E-98 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L12_05215 54766ee8ca58d8b21ca3a89cff70d639 359 Gene3D G3DSA:3.40.1190.20 1 261 7.7E-98 T 23-10-2018 IPR029056 Ribokinase-like A3L12_05215 54766ee8ca58d8b21ca3a89cff70d639 359 Pfam PF08543 Phosphomethylpyrimidine kinase 11 254 1.3E-91 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A3L12_05215 54766ee8ca58d8b21ca3a89cff70d639 359 SUPERFAMILY SSF53613 1 265 1.31E-76 T 23-10-2018 IPR029056 Ribokinase-like A3L12_05130 4ce0fdef2b9b86fe36f659f5bc9a6528 720 Gene3D G3DSA:2.60.40.10 212 312 3.0E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_05130 4ce0fdef2b9b86fe36f659f5bc9a6528 720 SUPERFAMILY SSF52317 472 719 5.26E-23 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_05130 4ce0fdef2b9b86fe36f659f5bc9a6528 720 Pfam PF09822 ABC-type uncharacterized transport system 237 595 1.8E-7 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 A3L12_05130 4ce0fdef2b9b86fe36f659f5bc9a6528 720 Gene3D G3DSA:3.40.50.880 483 716 3.7E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 SMART SM00382 34 240 5.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 5.2E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 SUPERFAMILY SSF52540 33 313 1.36E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 Pfam PF00005 ABC transporter 25 182 1.7E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_02525 ebba59f7678e37a52cd952d5a494109a 319 Gene3D G3DSA:3.40.50.300 2 319 1.9E-105 T 23-10-2018 A3L12_06190 604ac56102d2e1a55c2c79c5d3769822 267 Gene3D G3DSA:1.25.40.10 86 209 1.6E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_00405 98b58e66a429b01c3c5551a033428906 178 SUPERFAMILY SSF52499 4 177 1.83E-54 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L12_00405 98b58e66a429b01c3c5551a033428906 178 Gene3D G3DSA:3.40.50.850 1 178 8.6E-72 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L12_00405 98b58e66a429b01c3c5551a033428906 178 Pfam PF00857 Isochorismatase family 5 176 6.0E-44 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L12_07365 a68f052cee539d606cb1a0d8d1c34d61 194 Pfam PF03956 Lysine exporter LysO 9 191 1.1E-55 T 23-10-2018 IPR005642 Lysine exporter LysO A3L12_07365 a68f052cee539d606cb1a0d8d1c34d61 194 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 188 6.0E-47 T 23-10-2018 IPR005642 Lysine exporter LysO A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 33.069 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 8 169 9.3E-37 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 PIRSF PIRSF005285 8 171 1.7E-64 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 Gene3D G3DSA:3.40.1350.10 79 171 2.3E-32 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 1.5E-30 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 6 69 9.5E-22 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 SUPERFAMILY SSF55267 6 77 3.34E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 SUPERFAMILY SSF53032 79 169 6.15E-29 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L12_03795 4f91d27d56cfadba03ffd77035ded2a5 171 Gene3D G3DSA:3.40.1170.20 5 73 1.4E-17 T 23-10-2018 A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 PIRSF PIRSF005644 2 330 4.8E-91 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 Gene3D G3DSA:3.30.1330.10 3 143 1.3E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 310 3.2E-28 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 SUPERFAMILY SSF55326 5 144 4.54E-26 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 SUPERFAMILY SSF56042 146 314 1.18E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 140 1.9E-15 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_07785 d018e5bd5dca501b23efb3e0f09d221c 330 Gene3D G3DSA:3.90.650.10 146 330 9.7E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_02030 8ef6f883996bb0160880c390d7555e85 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 1.7E-41 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A3L12_02030 8ef6f883996bb0160880c390d7555e85 106 Gene3D G3DSA:1.10.10.1410 1 58 8.3E-30 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_02030 8ef6f883996bb0160880c390d7555e85 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 2.9E-19 T 23-10-2018 A3L12_02030 8ef6f883996bb0160880c390d7555e85 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 103 14.608 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_04980 9df4376232d42b6b4b3127217da73bac 455 SUPERFAMILY SSF111283 2 450 1.96E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L12_04980 9df4376232d42b6b4b3127217da73bac 455 PIRSF PIRSF004919 1 455 5.2E-152 T 23-10-2018 IPR025502 TldD A3L12_04980 9df4376232d42b6b4b3127217da73bac 455 Gene3D G3DSA:3.30.2290.10 1 221 1.8E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L12_04980 9df4376232d42b6b4b3127217da73bac 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 4.3E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L12_04635 75c50c22a95c4f5ccaad67f1e61de7b5 514 Gene3D G3DSA:1.20.1730.10 24 514 4.1E-60 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L12_04635 75c50c22a95c4f5ccaad67f1e61de7b5 514 Pfam PF00474 Sodium:solute symporter family 36 449 4.9E-36 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L12_04310 6968a672c969329de64b6f603601a1c2 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 88 1.3E-14 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L12_04035 0ab9e34ec5b30783b7d0e56c2a3c7f8a 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 103 5.4E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L12_04035 0ab9e34ec5b30783b7d0e56c2a3c7f8a 105 Gene3D G3DSA:3.30.70.20 7 105 4.2E-17 T 23-10-2018 A3L12_04035 0ab9e34ec5b30783b7d0e56c2a3c7f8a 105 SUPERFAMILY SSF54862 32 102 8.68E-24 T 23-10-2018 A3L12_04035 0ab9e34ec5b30783b7d0e56c2a3c7f8a 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_04035 0ab9e34ec5b30783b7d0e56c2a3c7f8a 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 2.1E-12 T 23-10-2018 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Gene3D G3DSA:1.10.290.10 279 406 1.1E-117 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Gene3D G3DSA:1.10.460.10 163 573 1.1E-117 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 322 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Pfam PF01131 DNA topoisomerase 156 564 1.1E-126 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 652 2.5E-280 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 SMART SM00437 271 527 2.8E-97 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 SUPERFAMILY SSF56712 2 634 1.83E-158 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 SMART SM00493 2 129 6.5E-16 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 622 659 2.2E-12 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 SUPERFAMILY SSF57783 619 661 5.78E-5 T 23-10-2018 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Gene3D G3DSA:2.70.20.10 220 475 1.1E-117 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 691 48.979 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Pfam PF01751 Toprim domain 3 139 1.5E-17 T 23-10-2018 IPR006171 TOPRIM domain A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 Gene3D G3DSA:3.40.50.140 1 154 6.5E-29 T 23-10-2018 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 SMART SM00436 131 226 1.5E-41 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 9.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 9.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 9.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 9.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01975 7832752e52791ffed8ea12a272dc6ad3 703 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 9.5E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 249 1.6E-5 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 SUPERFAMILY SSF55347 133 288 3.27E-26 T 23-10-2018 A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 SUPERFAMILY SSF51735 3 152 5.07E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 Gene3D G3DSA:3.30.360.10 126 336 4.5E-43 T 23-10-2018 A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 19 122 5.4E-20 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L12_01510 5fdfb153ff33fc68fa04d73fb3068a0a 337 Gene3D G3DSA:3.40.50.720 1 125 8.8E-26 T 23-10-2018 A3L12_04650 e7655ab620ac609e2f09c0959af3932c 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 306 1.1E-113 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L12_04650 e7655ab620ac609e2f09c0959af3932c 331 SUPERFAMILY SSF50891 173 289 3.79E-13 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L12_04650 e7655ab620ac609e2f09c0959af3932c 331 SMART SM00797 23 299 2.8E-142 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L12_04650 e7655ab620ac609e2f09c0959af3932c 331 Gene3D G3DSA:2.40.100.10 171 310 2.0E-52 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L12_04650 e7655ab620ac609e2f09c0959af3932c 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 282 1.1E-85 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L12_00555 b2562411786fe8957027af3d80a2866e 102 Gene3D G3DSA:2.40.30.10 14 102 5.8E-11 T 23-10-2018 A3L12_00555 b2562411786fe8957027af3d80a2866e 102 SUPERFAMILY SSF50447 20 100 6.86E-10 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_05870 a623fd5e70852a57bacc42a14c1ade32 249 SUPERFAMILY SSF69796 3 198 6.54E-60 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L12_05870 a623fd5e70852a57bacc42a14c1ade32 249 Gene3D G3DSA:3.30.1360.170 1 202 1.3E-61 T 23-10-2018 A3L12_05870 a623fd5e70852a57bacc42a14c1ade32 249 Pfam PF02511 Thymidylate synthase complementing protein 8 198 3.8E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L12_05870 a623fd5e70852a57bacc42a14c1ade32 249 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 199 1.5E-53 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L12_05870 a623fd5e70852a57bacc42a14c1ade32 249 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.481 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 Gene3D G3DSA:3.40.1190.20 1 285 7.6E-63 T 23-10-2018 IPR029056 Ribokinase-like A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 SUPERFAMILY SSF53613 1 275 1.15E-63 T 23-10-2018 IPR029056 Ribokinase-like A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 PRINTS PR00990 Ribokinase signature 166 181 1.9E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 PRINTS PR00990 Ribokinase signature 8 29 1.9E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 PRINTS PR00990 Ribokinase signature 105 118 1.9E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 PRINTS PR00990 Ribokinase signature 198 209 1.9E-6 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L12_04075 d6424eb47d931c9e87c0cd8f2cc7046f 296 Pfam PF00294 pfkB family carbohydrate kinase 6 273 2.6E-42 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L12_07470 3b38afd47c39127b777d5e830be5f730 138 PIRSF PIRSF037181 4 138 2.8E-30 T 23-10-2018 IPR014958 DGC A3L12_07470 3b38afd47c39127b777d5e830be5f730 138 Pfam PF08859 DGC domain 20 124 3.2E-30 T 23-10-2018 IPR014958 DGC A3L12_06855 fc3fab4d6dc12314d1b6e2574c679ce2 292 SMART SM00493 5 84 2.0E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L12_06855 fc3fab4d6dc12314d1b6e2574c679ce2 292 SUPERFAMILY SSF103657 121 190 4.81E-5 T 23-10-2018 IPR027267 AH/BAR domain superfamily A3L12_06855 fc3fab4d6dc12314d1b6e2574c679ce2 292 Pfam PF01751 Toprim domain 8 88 3.7E-7 T 23-10-2018 IPR006171 TOPRIM domain A3L12_06855 fc3fab4d6dc12314d1b6e2574c679ce2 292 Gene3D G3DSA:3.40.1360.10 4 121 2.5E-6 T 23-10-2018 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 Pfam PF01926 50S ribosome-binding GTPase 2 126 2.9E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 Gene3D G3DSA:1.10.8.470 126 215 4.2E-29 T 23-10-2018 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 SUPERFAMILY SSF81271 323 393 4.06E-17 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 SUPERFAMILY SSF52540 1 315 9.35E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 1.2E-33 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 Gene3D G3DSA:3.10.20.30 319 397 8.6E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 2.0E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 2.0E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 2.0E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 2.0E-30 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_04995 51d8049dea551d836fbb5f7e797c73df 397 Pfam PF02824 TGS domain 345 393 6.2E-11 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L12_05700 01b87ea40d9ad2741708508382978800 197 Gene3D G3DSA:3.40.50.12280 2 160 4.7E-47 T 23-10-2018 A3L12_05700 01b87ea40d9ad2741708508382978800 197 SUPERFAMILY SSF56770 5 154 1.18E-48 T 23-10-2018 A3L12_05700 01b87ea40d9ad2741708508382978800 197 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 24 135 3.1E-19 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_02510 4f21d92945c1c4a7849304e322a86889 843 Gene3D G3DSA:3.10.105.10 173 403 1.7E-15 T 23-10-2018 A3L12_02510 4f21d92945c1c4a7849304e322a86889 843 Gene3D G3DSA:3.40.190.10 34 170 1.4E-6 T 23-10-2018 A3L12_02510 4f21d92945c1c4a7849304e322a86889 843 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 55 350 1.3E-18 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L12_02510 4f21d92945c1c4a7849304e322a86889 843 SUPERFAMILY SSF53850 54 359 4.16E-22 T 23-10-2018 A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 217 226 - T 23-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 SUPERFAMILY SSF52402 4 249 1.43E-76 T 23-10-2018 A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 TIGRFAM TIGR00552 nadE: NAD+ synthetase 9 248 1.6E-81 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 251 52.484 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 Gene3D G3DSA:3.40.50.620 7 253 1.6E-89 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02540 b1fff9fb330e6e6ba02dee00ca97b486 253 Pfam PF02540 NAD synthase 9 248 2.0E-85 T 23-10-2018 IPR022310 NAD/GMP synthase A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 62 3.6E-17 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 61 2.0E-11 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 SMART SM01389 4 62 4.7E-31 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 62 28.44 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 SUPERFAMILY SSF63393 2 62 9.15E-24 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L12_03265 4e0f4946b1415dec111ea063d9d08999 62 Gene3D G3DSA:2.20.28.90 1 62 5.1E-32 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 Gene3D G3DSA:3.10.580.10 2 177 1.9E-39 T 23-10-2018 A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 SMART SM00116 79 126 1.7E-8 T 23-10-2018 IPR000644 CBS domain A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 SMART SM00116 14 61 5.6E-9 T 23-10-2018 IPR000644 CBS domain A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 Pfam PF00571 CBS domain 72 125 2.0E-11 T 23-10-2018 IPR000644 CBS domain A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 Pfam PF00571 CBS domain 7 60 2.2E-9 T 23-10-2018 IPR000644 CBS domain A3L12_07180 d3fdaaaa00e3aa50def80a4f692fdd16 179 SUPERFAMILY SSF54631 4 127 4.04E-30 T 23-10-2018 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.3E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.3E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.3E-9 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 SMART SM00344 5 111 5.2E-17 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 Gene3D G3DSA:3.30.70.920 57 149 2.4E-27 T 23-10-2018 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 Gene3D G3DSA:1.10.10.10 1 56 1.0E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 SUPERFAMILY SSF54909 66 147 1.02E-5 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 1.2E-13 T 23-10-2018 A3L12_05520 e682402744d84f48bfcc0139bb6277b6 149 SUPERFAMILY SSF46785 5 65 2.7E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00180 0ef9554e3f38cf1a688b2384f55d642a 661 Pfam PF04312 Protein of unknown function (DUF460) 210 350 7.8E-48 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 PRINTS PR00446 Hydrogen uptake protein signature 15 26 1.5E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 PRINTS PR00446 Hydrogen uptake protein signature 3 15 1.5E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 PRINTS PR00446 Hydrogen uptake protein signature 51 61 1.5E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 PRINTS PR00446 Hydrogen uptake protein signature 63 79 1.5E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 SUPERFAMILY SSF53163 2 148 1.96E-29 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 Pfam PF01750 Hydrogenase maturation protease 28 144 4.4E-17 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 4.2E-29 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_05490 2e4bafb2f5202212e3a45ddd8f925824 149 Gene3D G3DSA:3.40.50.1450 2 148 1.6E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L12_02555 25292895eb3ae92a7fd6da18b92a02f6 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 10 132 6.0E-31 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L12_02555 25292895eb3ae92a7fd6da18b92a02f6 135 PIRSF PIRSF005264 1 135 5.2E-41 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L12_02555 25292895eb3ae92a7fd6da18b92a02f6 135 Hamap MF_00585 UPF0216 protein . 4 135 25.484 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L12_02555 25292895eb3ae92a7fd6da18b92a02f6 135 Pfam PF01886 Protein of unknown function DUF61 7 132 1.3E-32 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L12_03940 0f2ce758c92312edc4ae4da41477fdb7 149 SUPERFAMILY SSF52402 2 149 8.37E-25 T 23-10-2018 A3L12_03940 0f2ce758c92312edc4ae4da41477fdb7 149 Gene3D G3DSA:3.40.50.620 1 149 2.1E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03940 0f2ce758c92312edc4ae4da41477fdb7 149 Pfam PF00582 Universal stress protein family 2 149 6.0E-16 T 23-10-2018 IPR006016 UspA A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 263 268 4.2E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 Gene3D G3DSA:3.40.50.1370 135 291 3.2E-121 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 SUPERFAMILY SSF53671 2 305 1.57E-99 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 3.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 3.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 303 5.1E-128 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 Gene3D G3DSA:3.40.50.1370 7 300 3.2E-121 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 306 39.573 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 301 9.6E-27 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 2.0E-49 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L12_03870 687c92d2b0a3749c5ef66f9ebe2d5d74 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L12_07080 5911e0f32145111e50403cd06901fbce 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.005 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_07080 5911e0f32145111e50403cd06901fbce 67 SUPERFAMILY SSF57716 6 56 3.42E-20 T 23-10-2018 A3L12_07080 5911e0f32145111e50403cd06901fbce 67 SMART SM00746 7 45 1.1E-11 T 23-10-2018 IPR011017 TRASH domain A3L12_07080 5911e0f32145111e50403cd06901fbce 67 Pfam PF01246 Ribosomal protein L24e 3 60 9.3E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A3L12_07080 5911e0f32145111e50403cd06901fbce 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A3L12_07080 5911e0f32145111e50403cd06901fbce 67 Gene3D G3DSA:2.30.170.20 2 66 5.6E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 697 739 8.4E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 904 24.01 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Gene3D G3DSA:3.30.54.20 670 721 3.0E-29 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Gene3D G3DSA:3.30.980.10 600 669 6.3E-22 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 889 4.7E-229 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Gene3D G3DSA:3.10.310.40 808 907 3.2E-20 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 SUPERFAMILY SSF101353 309 522 2.62E-49 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Gene3D G3DSA:3.30.930.10 1 260 1.3E-112 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 SUPERFAMILY SSF50447 511 593 1.27E-18 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Pfam PF01411 tRNA synthetases class II (A) 61 598 3.9E-152 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 906 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 SMART SM00863 697 740 2.7E-18 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Gene3D G3DSA:2.40.30.130 501 594 3.5E-32 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 SUPERFAMILY SSF55186 598 747 9.42E-49 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 SUPERFAMILY SSF55681 57 264 2.61E-57 T 23-10-2018 A3L12_00280 12451ebc8569f02096897072f41e5a08 907 Pfam PF02272 DHHA1 domain 777 906 3.9E-19 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 SUPERFAMILY SSF74650 386 648 1.88E-92 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 Pfam PF03065 Glycosyl hydrolase family 57 5 288 9.8E-67 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 Pfam PF09094 Domain of unknown function (DUF1925) 309 380 1.6E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 SUPERFAMILY SSF88688 309 381 2.94E-37 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 SUPERFAMILY SSF88713 3 307 7.31E-71 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 Pfam PF09095 Domain of unknown function (DUF1926) 390 644 6.9E-75 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 7.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 Gene3D G3DSA:3.20.110.20 1 379 9.8E-179 T 23-10-2018 A3L12_00225 977f9d79c5330d960ccb01d2098c8f21 649 Gene3D G3DSA:2.70.98.10 386 649 5.7E-82 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 307 1.3E-47 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 Gene3D G3DSA:3.30.230.10 16 141 2.2E-11 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 Pfam PF08544 GHMP kinases C terminal 203 273 2.0E-4 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 Pfam PF00288 GHMP kinases N terminal domain 76 136 5.2E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 SUPERFAMILY SSF54211 2 146 9.87E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_06105 06a0b10285831ac7275b765c1acfeda6 322 PIRSF PIRSF004884 1 309 3.2E-99 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L12_07270 0100e0edab2dd1188f60d59affbb1d18 129 SUPERFAMILY SSF53146 3 115 3.92E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_07270 0100e0edab2dd1188f60d59affbb1d18 129 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 113 4.6E-15 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L12_07270 0100e0edab2dd1188f60d59affbb1d18 129 Gene3D G3DSA:3.30.420.130 2 123 2.6E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_07645 4ae1140bf328b6bc0091308457cb16a3 251 SUPERFAMILY SSF52467 2 246 9.46E-90 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L12_07645 4ae1140bf328b6bc0091308457cb16a3 251 Gene3D G3DSA:3.40.50.1220 12 242 3.2E-90 T 23-10-2018 A3L12_07645 4ae1140bf328b6bc0091308457cb16a3 251 Pfam PF02146 Sir2 family 20 198 6.0E-57 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A3L12_07645 4ae1140bf328b6bc0091308457cb16a3 251 Gene3D G3DSA:3.30.1600.10 29 168 3.2E-90 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A3L12_07645 4ae1140bf328b6bc0091308457cb16a3 251 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 59.697 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A3L12_08035 a5750257be40a778f86fe10f12e8dd45 124 Gene3D G3DSA:3.30.70.120 1 123 8.1E-52 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L12_08035 a5750257be40a778f86fe10f12e8dd45 124 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 2.5E-37 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A3L12_08035 a5750257be40a778f86fe10f12e8dd45 124 SUPERFAMILY SSF54913 8 104 1.0E-33 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 SUPERFAMILY SSF53474 7 252 2.11E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 Gene3D G3DSA:3.40.50.1820 2 257 3.4E-67 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 1.6E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 1.6E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 1.6E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L12_07310 6b8ba05ee3ee3aa98d0b611497132071 259 Pfam PF12146 Serine aminopeptidase, S33 14 240 1.8E-67 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L12_07730 28969267b2277d6492872ee14526b200 152 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 97 144 2.6E-14 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A3L12_07730 28969267b2277d6492872ee14526b200 152 Gene3D G3DSA:2.30.130.90 45 148 3.6E-9 T 23-10-2018 A3L12_05680 0b5554cc841275a2755fc120d01c18e0 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 2.7E-31 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L12_04610 3e4710765c99aa9055340597a45aba6b 142 Pfam PF02391 MoaE protein 5 117 7.6E-35 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L12_04610 3e4710765c99aa9055340597a45aba6b 142 Gene3D G3DSA:3.90.1170.40 1 136 3.7E-48 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L12_04610 3e4710765c99aa9055340597a45aba6b 142 SUPERFAMILY SSF54690 3 135 3.66E-45 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L12_03820 e5b5b4c7dee8efabbc31f11db15c2b5e 440 Pfam PF09376 NurA domain 43 405 2.9E-66 T 23-10-2018 IPR018977 NurA domain A3L12_03820 e5b5b4c7dee8efabbc31f11db15c2b5e 440 SMART SM00933 42 405 2.6E-28 T 23-10-2018 IPR018977 NurA domain A3L12_03820 e5b5b4c7dee8efabbc31f11db15c2b5e 440 PIRSF PIRSF018871 1 440 1.6E-117 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like A3L12_00470 594f8eeeedf6336f0e7343c5f5ac73e0 131 Gene3D G3DSA:3.30.110.150 47 131 6.4E-23 T 23-10-2018 IPR038594 SepF-like superfamily A3L12_00470 594f8eeeedf6336f0e7343c5f5ac73e0 131 Pfam PF04472 Cell division protein SepF 57 129 1.4E-12 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A3L12_00470 594f8eeeedf6336f0e7343c5f5ac73e0 131 PIRSF PIRSF019313 1 131 2.1E-28 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A3L12_01530 ad6ca351d656adb4ef60d5adf2f6e050 492 SUPERFAMILY SSF53743 53 328 4.58E-47 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L12_01530 ad6ca351d656adb4ef60d5adf2f6e050 492 Pfam PF02952 L-fucose isomerase, C-terminal domain 346 476 2.3E-25 T 23-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A3L12_04215 42db5c3f1ca158cbf6f10ebe95833bda 205 Gene3D G3DSA:3.40.50.150 25 190 1.8E-36 T 23-10-2018 A3L12_04215 42db5c3f1ca158cbf6f10ebe95833bda 205 Pfam PF08241 Methyltransferase domain 41 135 6.7E-25 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L12_04215 42db5c3f1ca158cbf6f10ebe95833bda 205 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A3L12_04215 42db5c3f1ca158cbf6f10ebe95833bda 205 SUPERFAMILY SSF53335 18 193 1.45E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07675 0a531b4a6cf3919018f03548559adc32 416 SMART SM00471 48 188 5.6E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L12_07675 0a531b4a6cf3919018f03548559adc32 416 SUPERFAMILY SSF109604 3 397 1.41E-89 T 23-10-2018 A3L12_07675 0a531b4a6cf3919018f03548559adc32 416 Pfam PF01966 HD domain 52 124 2.9E-16 T 23-10-2018 IPR006674 HD domain A3L12_07675 0a531b4a6cf3919018f03548559adc32 416 Gene3D G3DSA:1.10.3210.10 3 290 2.5E-86 T 23-10-2018 A3L12_02170 cdc79e64c26fe6091bf003fcbf631e27 374 Gene3D G3DSA:1.20.1530.20 2 373 6.8E-39 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_02170 cdc79e64c26fe6091bf003fcbf631e27 374 Pfam PF00999 Sodium/hydrogen exchanger family 8 361 1.1E-21 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L12_03690 6c17ca8e038e4f9409dd8a7e4fa72bfa 306 Gene3D G3DSA:3.60.20.30 176 304 5.7E-33 T 23-10-2018 A3L12_03690 6c17ca8e038e4f9409dd8a7e4fa72bfa 306 SUPERFAMILY SSF56235 17 300 1.0E-87 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_03690 6c17ca8e038e4f9409dd8a7e4fa72bfa 306 Pfam PF01112 Asparaginase 3 300 3.1E-93 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A3L12_04050 bc89621929e2f6a7166a2d5a5fcb77ae 293 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A3L12_04050 bc89621929e2f6a7166a2d5a5fcb77ae 293 Gene3D G3DSA:3.40.50.300 17 281 2.1E-81 T 23-10-2018 A3L12_04050 bc89621929e2f6a7166a2d5a5fcb77ae 293 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 1.0E-95 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L12_04050 bc89621929e2f6a7166a2d5a5fcb77ae 293 SUPERFAMILY SSF52540 20 265 9.99E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04050 bc89621929e2f6a7166a2d5a5fcb77ae 293 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.19 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L12_05670 c36238c165f368ebab601ccb6787105c 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 1.2E-20 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L12_00105 65bca33d1612decc3e6f9c27d9e27593 648 Gene3D G3DSA:3.40.50.300 349 636 6.1E-100 T 23-10-2018 A3L12_00105 65bca33d1612decc3e6f9c27d9e27593 648 Gene3D G3DSA:3.30.450.380 134 348 8.4E-67 T 23-10-2018 A3L12_00105 65bca33d1612decc3e6f9c27d9e27593 648 SMART SM00382 381 546 0.0061 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_00105 65bca33d1612decc3e6f9c27d9e27593 648 Pfam PF00437 Type II/IV secretion system protein 254 510 4.5E-63 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L12_00105 65bca33d1612decc3e6f9c27d9e27593 648 SUPERFAMILY SSF52540 234 556 2.07E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 Gene3D G3DSA:3.90.1490.10 137 230 9.6E-30 T 23-10-2018 A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 SUPERFAMILY SSF52402 1 220 1.55E-71 T 23-10-2018 A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 210 3.9E-86 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 221 1.5E-89 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 Gene3D G3DSA:3.40.50.620 1 134 3.3E-45 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 Pfam PF01902 Diphthamide synthase 1 219 7.9E-83 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 PIRSF PIRSF039123 1 231 8.1E-79 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_02075 27a48436d9569f94eed166c3db1b264d 232 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 1.2E-79 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 SMART SM00344 2 108 6.6E-45 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 3.1E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 3.1E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 3.1E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 Gene3D G3DSA:1.10.10.10 1 52 4.9E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 3.2E-14 T 23-10-2018 A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 SUPERFAMILY SSF46785 2 62 1.05E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 SUPERFAMILY SSF54909 62 141 5.5E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 1.0E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_04225 6d4a3c33437605ddd641c015d3902e1b 141 Gene3D G3DSA:3.30.70.920 65 141 3.3E-19 T 23-10-2018 A3L12_02115 f1f0667c55bfeeef5cc8a09f868d87f7 63 Gene3D G3DSA:1.10.1220.10 11 46 2.4E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L12_02115 f1f0667c55bfeeef5cc8a09f868d87f7 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 9.1E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L12_02115 f1f0667c55bfeeef5cc8a09f868d87f7 63 SUPERFAMILY SSF47598 3 46 1.67E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L12_08120 dee7596bf9ac0c871c61f1d15540452c 257 Pfam PF01420 Type I restriction modification DNA specificity domain 45 225 1.7E-17 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L12_08120 dee7596bf9ac0c871c61f1d15540452c 257 Gene3D G3DSA:3.90.220.20 26 243 9.2E-45 T 23-10-2018 A3L12_08120 dee7596bf9ac0c871c61f1d15540452c 257 SUPERFAMILY SSF116734 40 238 2.29E-45 T 23-10-2018 A3L12_06285 4dc4758598b7511acbfd0468ea67e982 118 Gene3D G3DSA:3.40.1490.10 1 118 1.4E-46 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L12_06285 4dc4758598b7511acbfd0468ea67e982 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 5.9E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L12_06285 4dc4758598b7511acbfd0468ea67e982 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 5.6E-42 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L12_06285 4dc4758598b7511acbfd0468ea67e982 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.35 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A3L12_06285 4dc4758598b7511acbfd0468ea67e982 118 SUPERFAMILY SSF102462 3 118 7.5E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L12_06960 f33bdae458b93768dffbdc50044fdcc2 348 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 329 348 6.3E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L12_07165 0cc7892b2288b70492517e647d69d511 377 SUPERFAMILY SSF56796 2 376 3.01E-97 T 23-10-2018 A3L12_07165 0cc7892b2288b70492517e647d69d511 377 Gene3D G3DSA:1.20.1090.10 185 377 1.4E-56 T 23-10-2018 A3L12_07165 0cc7892b2288b70492517e647d69d511 377 Gene3D G3DSA:3.40.50.1970 1 183 1.1E-41 T 23-10-2018 A3L12_07165 0cc7892b2288b70492517e647d69d511 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 366 1.7E-96 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L12_06955 3c8030f69b3206b6f990a312ef6a37ab 483 SUPERFAMILY SSF53850 87 325 6.67E-38 T 23-10-2018 A3L12_06955 3c8030f69b3206b6f990a312ef6a37ab 483 Gene3D G3DSA:3.40.190.10 153 272 2.2E-32 T 23-10-2018 A3L12_06955 3c8030f69b3206b6f990a312ef6a37ab 483 Gene3D G3DSA:3.40.190.10 88 308 2.2E-32 T 23-10-2018 A3L12_06955 3c8030f69b3206b6f990a312ef6a37ab 483 Pfam PF13416 Bacterial extracellular solute-binding protein 90 328 5.1E-18 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L12_05305 e364c054fe449b1df6fae5f951ad691a 324 SUPERFAMILY SSF102114 11 257 1.31E-13 T 23-10-2018 A3L12_05305 e364c054fe449b1df6fae5f951ad691a 324 PIRSF PIRSF004954 1 319 3.5E-97 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L12_05305 e364c054fe449b1df6fae5f951ad691a 324 Pfam PF04055 Radical SAM superfamily 25 179 2.3E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_05305 e364c054fe449b1df6fae5f951ad691a 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 4.0E-121 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L12_05305 e364c054fe449b1df6fae5f951ad691a 324 SMART SM00729 17 247 8.6E-21 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 3.0E-125 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 Gene3D G3DSA:3.40.50.300 43 252 1.8E-88 T 23-10-2018 A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 Gene3D G3DSA:1.20.5.170 1 38 3.0E-5 T 23-10-2018 A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 SMART SM00382 44 194 2.7E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 Pfam PF03308 ArgK protein 18 278 2.0E-100 T 23-10-2018 A3L12_06675 5ab52a4cc33aeaf388b9171b176f9e16 319 SUPERFAMILY SSF52540 2 311 1.4E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02460 c127883e2a892634802ad7884baa49cd 366 Gene3D G3DSA:1.20.1690.10 112 209 6.6E-59 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 Gene3D G3DSA:1.20.1690.10 220 323 6.6E-59 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 4.1E-67 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 SUPERFAMILY SSF103486 35 362 6.54E-79 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 362 5.3E-101 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 25.016 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L12_02460 c127883e2a892634802ad7884baa49cd 366 Gene3D G3DSA:1.10.132.50 35 354 6.6E-59 T 23-10-2018 A3L12_02650 05455dae20ed96244874420174d786ff 501 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 197 235 0.0015 T 23-10-2018 IPR013431 Delta-60 repeat A3L12_02650 05455dae20ed96244874420174d786ff 501 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 41 78 2.2E-4 T 23-10-2018 IPR013431 Delta-60 repeat A3L12_02650 05455dae20ed96244874420174d786ff 501 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 145 183 1.5E-5 T 23-10-2018 IPR013431 Delta-60 repeat A3L12_02650 05455dae20ed96244874420174d786ff 501 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 152 183 7.8E-5 T 23-10-2018 IPR013431 Delta-60 repeat A3L12_02650 05455dae20ed96244874420174d786ff 501 SUPERFAMILY SSF63829 38 340 3.99E-15 T 23-10-2018 A3L12_02650 05455dae20ed96244874420174d786ff 501 Gene3D G3DSA:2.80.10.50 218 344 4.5E-6 T 23-10-2018 A3L12_02650 05455dae20ed96244874420174d786ff 501 Gene3D G3DSA:2.80.10.50 70 196 2.7E-7 T 23-10-2018 A3L12_07570 4f974c2834db37e016071cc181a48afd 252 Pfam PF01917 Archaebacterial flagellin 5 238 5.6E-43 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L12_07570 4f974c2834db37e016071cc181a48afd 252 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 3 26 1.2E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L12_02515 d8b0afec98e7660ea33382f3113b79e4 351 SUPERFAMILY SSF161098 119 327 3.53E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02515 d8b0afec98e7660ea33382f3113b79e4 351 Gene3D G3DSA:1.10.3720.10 115 341 1.0E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02515 d8b0afec98e7660ea33382f3113b79e4 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 344 7.3E-36 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_04365 b99ba4da61c8f15861504b888e0eda95 175 Gene3D G3DSA:3.40.50.300 1 175 1.3E-65 T 23-10-2018 A3L12_04365 b99ba4da61c8f15861504b888e0eda95 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 4.3E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L12_04365 b99ba4da61c8f15861504b888e0eda95 175 PIRSF PIRSF015617 1 175 5.8E-64 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L12_04365 b99ba4da61c8f15861504b888e0eda95 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 3.8E-69 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L12_04365 b99ba4da61c8f15861504b888e0eda95 175 SUPERFAMILY SSF52540 4 175 9.08E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03535 25900ffb375ad114610d2c5daac01c89 207 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 1.2E-34 T 23-10-2018 A3L12_03535 25900ffb375ad114610d2c5daac01c89 207 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 3.8E-57 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A3L12_03535 25900ffb375ad114610d2c5daac01c89 207 Gene3D G3DSA:3.40.50.1000 1 202 2.8E-50 T 23-10-2018 IPR023214 HAD superfamily A3L12_03535 25900ffb375ad114610d2c5daac01c89 207 SUPERFAMILY SSF56784 2 205 2.4E-39 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_03535 25900ffb375ad114610d2c5daac01c89 207 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 172 4.3E-20 T 23-10-2018 A3L12_04455 ad3fc7751c3310a2a3535794ae99f342 70 SUPERFAMILY SSF50249 10 70 5.37E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_04455 ad3fc7751c3310a2a3535794ae99f342 70 Pfam PF01938 TRAM domain 14 70 2.4E-15 T 23-10-2018 IPR002792 TRAM domain A3L12_04455 ad3fc7751c3310a2a3535794ae99f342 70 Gene3D G3DSA:2.40.50.140 6 70 3.1E-26 T 23-10-2018 A3L12_05710 35d93e03574e2d01f696100dcd80ba1d 391 SUPERFAMILY SSF56762 39 391 1.09E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05710 35d93e03574e2d01f696100dcd80ba1d 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05710 35d93e03574e2d01f696100dcd80ba1d 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 2.7E-70 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05710 35d93e03574e2d01f696100dcd80ba1d 391 Gene3D G3DSA:1.10.645.20 27 391 5.5E-113 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05175 d727e963be4ed4be1f660a082de81302 242 SMART SM00470 19 114 1.5E-13 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L12_05175 d727e963be4ed4be1f660a082de81302 242 Pfam PF02195 ParB-like nuclease domain 22 92 7.1E-10 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L12_05175 d727e963be4ed4be1f660a082de81302 242 SUPERFAMILY SSF110849 13 241 4.97E-60 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L12_05175 d727e963be4ed4be1f660a082de81302 242 Gene3D G3DSA:3.30.1760.10 102 226 2.2E-69 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A3L12_05175 d727e963be4ed4be1f660a082de81302 242 Gene3D G3DSA:3.90.1530.10 1 101 6.8E-41 T 23-10-2018 A3L12_06225 9136f01f6ec0b8698329095498757426 417 SUPERFAMILY SSF53448 2 311 2.7E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_06225 9136f01f6ec0b8698329095498757426 417 Pfam PF00483 Nucleotidyl transferase 2 231 9.1E-36 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L12_06225 9136f01f6ec0b8698329095498757426 417 Gene3D G3DSA:2.160.10.10 224 409 9.9E-58 T 23-10-2018 A3L12_06225 9136f01f6ec0b8698329095498757426 417 SUPERFAMILY SSF51161 243 408 2.36E-38 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L12_06225 9136f01f6ec0b8698329095498757426 417 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 364 398 2.0E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_06225 9136f01f6ec0b8698329095498757426 417 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 286 1.2E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_06225 9136f01f6ec0b8698329095498757426 417 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 397 6.1E-152 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A3L12_06225 9136f01f6ec0b8698329095498757426 417 Gene3D G3DSA:3.90.550.10 1 223 4.0E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_06870 fa22bd29737ba8f35a1846ea722a56aa 237 PIRSF PIRSF015736 1 237 1.1E-88 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A3L12_06870 fa22bd29737ba8f35a1846ea722a56aa 237 Gene3D G3DSA:3.40.50.12500 6 237 1.1E-87 T 23-10-2018 A3L12_06870 fa22bd29737ba8f35a1846ea722a56aa 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 215 8.1E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.356 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 SUPERFAMILY SSF51621 4 262 9.42E-103 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 7.3E-107 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 PIRSF PIRSF000388 1 265 5.6E-104 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 Gene3D G3DSA:3.20.20.60 2 272 1.1E-109 T 23-10-2018 A3L12_07745 e68f1ca3e6801e286cc249e619ea1a0c 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 262 7.2E-90 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 SUPERFAMILY SSF116734 223 403 8.83E-36 T 23-10-2018 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 Gene3D G3DSA:3.90.220.20 4 208 7.8E-38 T 23-10-2018 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 SUPERFAMILY SSF116734 11 217 2.45E-39 T 23-10-2018 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 Pfam PF01420 Type I restriction modification DNA specificity domain 230 381 1.9E-10 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 Pfam PF01420 Type I restriction modification DNA specificity domain 20 197 7.5E-16 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L12_01340 2a9c9573a1c5bf9a91a8ae402136a450 405 Gene3D G3DSA:3.90.220.20 220 354 9.1E-23 T 23-10-2018 A3L12_00330 1f762e2a3959830534b8dd67e8c381bd 100 Pfam PF01910 Thiamine-binding protein 4 93 2.1E-31 T 23-10-2018 IPR002767 Thiamine-binding protein A3L12_00330 1f762e2a3959830534b8dd67e8c381bd 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 1.4E-28 T 23-10-2018 IPR002767 Thiamine-binding protein A3L12_00330 1f762e2a3959830534b8dd67e8c381bd 100 Gene3D G3DSA:3.30.70.930 1 97 3.6E-34 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L12_00330 1f762e2a3959830534b8dd67e8c381bd 100 SUPERFAMILY SSF89957 1 96 3.14E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 Gene3D G3DSA:3.30.70.920 59 150 5.3E-22 T 23-10-2018 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 SUPERFAMILY SSF54909 65 147 3.49E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 9.6E-16 T 23-10-2018 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.4E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 SUPERFAMILY SSF46785 4 63 8.79E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 Pfam PF01037 Lrp/AsnC ligand binding domain 79 142 2.9E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 SMART SM00344 5 114 2.8E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_04585 04040bf88e3559fe08ccfaf8301a505f 150 Gene3D G3DSA:1.10.10.10 5 55 6.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06630 e58c7183938299802e99174044ac5bbf 342 Pfam PF00534 Glycosyl transferases group 1 175 308 2.8E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L12_06630 e58c7183938299802e99174044ac5bbf 342 Gene3D G3DSA:3.40.50.2000 173 314 1.1E-31 T 23-10-2018 A3L12_06630 e58c7183938299802e99174044ac5bbf 342 Pfam PF13439 Glycosyltransferase Family 4 14 168 2.2E-28 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L12_06630 e58c7183938299802e99174044ac5bbf 342 SUPERFAMILY SSF53756 5 341 7.49E-74 T 23-10-2018 A3L12_06630 e58c7183938299802e99174044ac5bbf 342 Gene3D G3DSA:3.40.50.2000 1 172 2.3E-37 T 23-10-2018 A3L12_07695 3e47eab2607a9c3d1890f7443b029dff 336 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 41.941 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A3L12_07695 3e47eab2607a9c3d1890f7443b029dff 336 Gene3D G3DSA:3.40.910.10 3 336 2.0E-144 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A3L12_07695 3e47eab2607a9c3d1890f7443b029dff 336 Pfam PF01916 Deoxyhypusine synthase 34 331 7.2E-111 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L12_07695 3e47eab2607a9c3d1890f7443b029dff 336 SUPERFAMILY SSF52467 5 334 8.83E-115 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L12_07695 3e47eab2607a9c3d1890f7443b029dff 336 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 335 1.8E-120 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L12_01660 3b0b97422a20f3af9026f2b0c608b93b 225 SUPERFAMILY SSF56784 1 185 2.52E-17 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_01660 3b0b97422a20f3af9026f2b0c608b93b 225 Gene3D G3DSA:1.10.150.240 15 83 5.9E-12 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L12_01660 3b0b97422a20f3af9026f2b0c608b93b 225 Gene3D G3DSA:3.40.50.1000 3 140 5.9E-12 T 23-10-2018 IPR023214 HAD superfamily A3L12_01660 3b0b97422a20f3af9026f2b0c608b93b 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 135 2.0E-8 T 23-10-2018 A3L12_04390 20a658ff9165476a55aa22f2042960db 183 Pfam PF04407 Protein of unknown function (DUF531) 1 169 4.9E-74 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L12_04390 20a658ff9165476a55aa22f2042960db 183 PIRSF PIRSF006006 1 178 2.3E-82 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L12_04390 20a658ff9165476a55aa22f2042960db 183 Gene3D G3DSA:3.40.1280.10 84 171 5.3E-5 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L12_05805 73f5b812e84f524ba142867d981b7318 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 24.853 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05805 73f5b812e84f524ba142867d981b7318 86 SUPERFAMILY SSF57829 10 80 2.62E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_05805 73f5b812e84f524ba142867d981b7318 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 82 1.8E-36 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05805 73f5b812e84f524ba142867d981b7318 86 Gene3D G3DSA:2.20.25.30 9 86 1.4E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_05805 73f5b812e84f524ba142867d981b7318 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.7E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_02130 eb4059ecad8aff40421a84dd491ba29c 401 SUPERFAMILY SSF103473 3 391 1.05E-31 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_02130 eb4059ecad8aff40421a84dd491ba29c 401 Gene3D G3DSA:1.20.1250.20 2 390 6.5E-16 T 23-10-2018 A3L12_02130 eb4059ecad8aff40421a84dd491ba29c 401 Pfam PF07690 Major Facilitator Superfamily 22 354 2.1E-22 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_00530 d7df365349bab1525329c5533e876207 170 SUPERFAMILY SSF56300 1 159 8.86E-38 T 23-10-2018 A3L12_00530 d7df365349bab1525329c5533e876207 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 1.2E-32 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_00530 d7df365349bab1525329c5533e876207 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 6.5E-39 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L12_00530 d7df365349bab1525329c5533e876207 170 Gene3D G3DSA:3.60.21.10 1 159 2.4E-50 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_00530 d7df365349bab1525329c5533e876207 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A3L12_07950 0e76367922d84ea97d88b9589390a99e 382 SUPERFAMILY SSF53335 56 161 8.74E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07950 0e76367922d84ea97d88b9589390a99e 382 Gene3D G3DSA:3.40.50.150 41 235 4.3E-27 T 23-10-2018 A3L12_07950 0e76367922d84ea97d88b9589390a99e 382 Pfam PF09445 RNA cap guanine-N2 methyltransferase 85 154 4.5E-7 T 23-10-2018 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 Reactome: R-HSA-1368082|Reactome: R-HSA-1368108|Reactome: R-HSA-191859|Reactome: R-HSA-1989781|Reactome: R-HSA-2151201|Reactome: R-HSA-2426168|Reactome: R-HSA-381340|Reactome: R-HSA-400206|Reactome: R-HSA-400253 A3L12_02975 b1bee589ca206c1dd92909f0c4091136 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 315 4.1E-17 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L12_02975 b1bee589ca206c1dd92909f0c4091136 376 Pfam PF01385 Probable transposase 164 274 7.2E-27 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L12_02975 b1bee589ca206c1dd92909f0c4091136 376 Pfam PF12323 Helix-turn-helix domain 2 45 2.8E-9 T 23-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain A3L12_07390 68208199c1892168d8c231b920c5fa43 100 SUPERFAMILY SSF47240 6 86 7.74E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_07390 68208199c1892168d8c231b920c5fa43 100 Pfam PF02915 Rubrerythrin 24 91 3.4E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07390 68208199c1892168d8c231b920c5fa43 100 Gene3D G3DSA:1.20.1260.10 4 75 4.2E-10 T 23-10-2018 IPR012347 Ferritin-like A3L12_03530 410a939ccadac80a004f83411aca13d9 220 Gene3D G3DSA:3.40.50.150 1 220 1.9E-92 T 23-10-2018 A3L12_03530 410a939ccadac80a004f83411aca13d9 220 SUPERFAMILY SSF53335 6 214 2.03E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03530 410a939ccadac80a004f83411aca13d9 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 215 1.8E-64 T 23-10-2018 A3L12_03530 410a939ccadac80a004f83411aca13d9 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 10 216 3.1E-61 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L12_03530 410a939ccadac80a004f83411aca13d9 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 5 218 41.194 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L12_03530 410a939ccadac80a004f83411aca13d9 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 433 30.397 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Gene3D G3DSA:3.40.50.800 339 435 3.3E-19 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L12_00270 08ab4b4a95c84f961be8366533323072 437 PIRSF PIRSF001549 1 435 4.5E-134 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Pfam PF03129 Anticodon binding domain 342 433 2.5E-16 T 23-10-2018 IPR004154 Anticodon-binding A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Pfam PF13393 Histidyl-tRNA synthetase 10 324 1.3E-64 T 23-10-2018 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 423 2.4E-122 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Gene3D G3DSA:3.30.930.10 1 335 2.8E-107 T 23-10-2018 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 SUPERFAMILY SSF55681 6 329 3.19E-86 T 23-10-2018 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 SUPERFAMILY SSF52954 331 435 1.33E-19 T 23-10-2018 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 386 24.684 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L12_00270 08ab4b4a95c84f961be8366533323072 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 327 2.1E-82 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L12_04910 28b93c946ed08b4c3e4b7867cf921373 248 SUPERFAMILY SSF52141 98 233 9.81E-27 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04910 28b93c946ed08b4c3e4b7867cf921373 248 SMART SM00986 104 237 8.3E-17 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04910 28b93c946ed08b4c3e4b7867cf921373 248 SMART SM00987 104 237 8.3E-17 T 23-10-2018 A3L12_04910 28b93c946ed08b4c3e4b7867cf921373 248 Pfam PF03167 Uracil DNA glycosylase superfamily 105 223 7.7E-22 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04910 28b93c946ed08b4c3e4b7867cf921373 248 Gene3D G3DSA:3.40.470.10 60 244 1.2E-26 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L12_04275 d40db5b75afd50061cf0324379316e4a 135 Gene3D G3DSA:3.30.70.260 47 131 1.1E-13 T 23-10-2018 A3L12_04275 d40db5b75afd50061cf0324379316e4a 135 Pfam PF01842 ACT domain 58 117 1.3E-10 T 23-10-2018 IPR002912 ACT domain A3L12_04275 d40db5b75afd50061cf0324379316e4a 135 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 59 105 4.0E-4 T 23-10-2018 A3L12_04275 d40db5b75afd50061cf0324379316e4a 135 SUPERFAMILY SSF55021 57 130 3.14E-12 T 23-10-2018 A3L12_04095 3080653c31759c12e86f1251f007953d 278 SUPERFAMILY SSF52402 2 135 3.93E-23 T 23-10-2018 A3L12_04095 3080653c31759c12e86f1251f007953d 278 SUPERFAMILY SSF52402 152 276 6.87E-20 T 23-10-2018 A3L12_04095 3080653c31759c12e86f1251f007953d 278 Gene3D G3DSA:3.40.50.620 1 142 7.6E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_04095 3080653c31759c12e86f1251f007953d 278 PRINTS PR01438 Universal stress protein signature 254 276 1.9E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L12_04095 3080653c31759c12e86f1251f007953d 278 PRINTS PR01438 Universal stress protein signature 236 248 1.9E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L12_04095 3080653c31759c12e86f1251f007953d 278 PRINTS PR01438 Universal stress protein signature 2 20 1.9E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L12_04095 3080653c31759c12e86f1251f007953d 278 Gene3D G3DSA:3.40.50.620 148 278 6.4E-22 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_04095 3080653c31759c12e86f1251f007953d 278 Pfam PF00582 Universal stress protein family 1 132 1.0E-18 T 23-10-2018 IPR006016 UspA A3L12_04095 3080653c31759c12e86f1251f007953d 278 Pfam PF00582 Universal stress protein family 192 276 8.5E-16 T 23-10-2018 IPR006016 UspA A3L12_06495 e3405fcdb31f88b0db22259b49538c89 161 Pfam PF00011 Hsp20/alpha crystallin family 58 154 6.4E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A3L12_06495 e3405fcdb31f88b0db22259b49538c89 161 SUPERFAMILY SSF49764 39 153 1.33E-30 T 23-10-2018 IPR008978 HSP20-like chaperone A3L12_06495 e3405fcdb31f88b0db22259b49538c89 161 Gene3D G3DSA:2.60.40.790 11 159 3.0E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 SUPERFAMILY SSF46785 3 150 2.51E-60 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.391 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 SMART SM01413 3 139 6.8E-89 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 1.0E-57 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 Gene3D G3DSA:1.10.10.2700 1 150 2.0E-64 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_06550 403b4ec87f177a5b2cc9627bf6a09793 150 Pfam PF01090 Ribosomal protein S19e 3 138 6.2E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 SUPERFAMILY SSF52540 1 212 8.84E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 Pfam PF00406 Adenylate kinase 5 188 6.5E-42 T 23-10-2018 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 4.8E-74 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 Pfam PF05191 Adenylate kinase, active site lid 125 160 7.8E-19 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 PRINTS PR00094 Adenylate kinase signature 79 95 1.2E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 PRINTS PR00094 Adenylate kinase signature 158 173 1.2E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 PRINTS PR00094 Adenylate kinase signature 175 189 1.2E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 PRINTS PR00094 Adenylate kinase signature 4 17 1.2E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 PRINTS PR00094 Adenylate kinase signature 32 46 1.2E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 Gene3D G3DSA:3.40.50.300 1 220 4.0E-77 T 23-10-2018 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_07985 a580e40fb574bd9c08ad1d57a870e1bf 221 Hamap MF_00235 Adenylate kinase [adk]. 1 211 46.965 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L12_05340 89c61d332eacfb2ab699489955877e01 186 Gene3D G3DSA:3.40.920.10 1 185 7.2E-52 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_05340 89c61d332eacfb2ab699489955877e01 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.1E-33 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L12_05340 89c61d332eacfb2ab699489955877e01 186 SUPERFAMILY SSF53323 1 179 2.62E-39 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PIRSF PIRSF015592 1 201 4.0E-77 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 Gene3D G3DSA:3.40.630.20 1 201 3.7E-76 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 SUPERFAMILY SSF53182 1 197 7.06E-68 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.22 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 Pfam PF01470 Pyroglutamyl peptidase 1 198 9.7E-76 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 3.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 3.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 3.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 3.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 3.9E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 197 4.9E-74 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A3L12_00175 8b3d26ce1ddeeb64facdb41a9761b3e6 201 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A3L12_07650 4af1ff5033421c41370f3c43801c779e 137 Pfam PF12646 Domain of unknown function (DUF3783) 58 113 3.9E-14 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L12_07650 4af1ff5033421c41370f3c43801c779e 137 PIRSF PIRSF014543 1 123 5.4E-43 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L12_06620 043e07511fe03bb562acfa532527b42b 392 SUPERFAMILY SSF48452 12 317 1.37E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_06620 043e07511fe03bb562acfa532527b42b 392 Gene3D G3DSA:1.25.40.10 166 385 6.7E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_06620 043e07511fe03bb562acfa532527b42b 392 Gene3D G3DSA:1.25.40.10 11 160 2.2E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_06775 4120bbc5afca4db6d7b35539200bc409 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 138 5.3E-42 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L12_06775 4120bbc5afca4db6d7b35539200bc409 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 2.0E-65 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L12_06775 4120bbc5afca4db6d7b35539200bc409 144 Hamap MF_00498 UPF0179 protein . 2 141 24.005 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L12_06775 4120bbc5afca4db6d7b35539200bc409 144 PIRSF PIRSF006595 1 144 1.1E-49 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 PRINTS PR00354 7Fe ferredoxin signature 43 53 2.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 PRINTS PR00354 7Fe ferredoxin signature 70 87 2.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 PRINTS PR00354 7Fe ferredoxin signature 53 63 2.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 SUPERFAMILY SSF54862 3 144 3.24E-50 T 23-10-2018 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 Gene3D G3DSA:3.30.70.20 26 156 5.8E-40 T 23-10-2018 A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 Pfam PF13247 4Fe-4S dicluster domain 38 130 2.0E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 Pfam PF12800 4Fe-4S binding domain 9 21 0.014 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01290 b82977d452c0380d8fd5e4818368ee97 161 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_00695 f354996692abac0b20e3c6a55547e246 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A3L12_00695 f354996692abac0b20e3c6a55547e246 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 1.3E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A3L12_00695 f354996692abac0b20e3c6a55547e246 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 48.065 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00695 f354996692abac0b20e3c6a55547e246 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 2.6E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L12_00695 f354996692abac0b20e3c6a55547e246 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 1.3E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00695 f354996692abac0b20e3c6a55547e246 235 Gene3D G3DSA:3.30.230.10 123 214 1.6E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_00695 f354996692abac0b20e3c6a55547e246 235 SUPERFAMILY SSF54211 138 210 3.29E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_00695 f354996692abac0b20e3c6a55547e246 235 Gene3D G3DSA:3.30.160.770 12 122 4.8E-38 T 23-10-2018 A3L12_00695 f354996692abac0b20e3c6a55547e246 235 SUPERFAMILY SSF54768 62 125 2.41E-18 T 23-10-2018 A3L12_02875 7fa84d337540d25568babc50e3744364 476 SUPERFAMILY SSF53649 15 462 1.06E-42 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L12_02875 7fa84d337540d25568babc50e3744364 476 Gene3D G3DSA:3.40.720.10 10 303 5.3E-50 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L12_02875 7fa84d337540d25568babc50e3744364 476 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 1.4E-62 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L12_01870 6d77789c30b6fe07a4ab4902a3ebde73 241 SUPERFAMILY SSF52540 14 219 2.62E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01870 6d77789c30b6fe07a4ab4902a3ebde73 241 Hamap MF_02040 Iron-sulfur cluster carrier protein. 7 235 27.086 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L12_01870 6d77789c30b6fe07a4ab4902a3ebde73 241 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 16 219 7.1E-52 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L12_01870 6d77789c30b6fe07a4ab4902a3ebde73 241 Gene3D G3DSA:3.40.50.300 1 222 4.1E-63 T 23-10-2018 A3L12_01550 dd9e0cc109e8d8154d12e504ec5c6ae4 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 21.153 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01550 dd9e0cc109e8d8154d12e504ec5c6ae4 67 SUPERFAMILY SSF116820 1 60 4.05E-22 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01550 dd9e0cc109e8d8154d12e504ec5c6ae4 67 Pfam PF00833 Ribosomal S17 1 64 3.5E-14 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01550 dd9e0cc109e8d8154d12e504ec5c6ae4 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_01550 dd9e0cc109e8d8154d12e504ec5c6ae4 67 Gene3D G3DSA:1.10.60.20 1 62 1.6E-27 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00140 7ec362708ddb592b7ed96ddc9bd95654 317 SUPERFAMILY SSF52540 13 287 1.39E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00140 7ec362708ddb592b7ed96ddc9bd95654 317 Gene3D G3DSA:3.40.50.300 21 187 2.2E-46 T 23-10-2018 A3L12_00140 7ec362708ddb592b7ed96ddc9bd95654 317 Gene3D G3DSA:1.10.8.300 202 311 6.6E-37 T 23-10-2018 A3L12_00140 7ec362708ddb592b7ed96ddc9bd95654 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 6.1E-67 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L12_00140 7ec362708ddb592b7ed96ddc9bd95654 317 PIRSF PIRSF002849 1 316 2.1E-137 T 23-10-2018 A3L12_00200 4b199d1bc25b793fe18f1229e6bb495c 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 6.0E-53 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L12_00200 4b199d1bc25b793fe18f1229e6bb495c 391 Gene3D G3DSA:1.20.1530.20 1 391 1.3E-74 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_00110 ebcc2aa97120b7d59dd9914d7c13a90c 354 Gene3D G3DSA:1.20.81.30 177 286 5.6E-11 T 23-10-2018 A3L12_00110 ebcc2aa97120b7d59dd9914d7c13a90c 354 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 3.4E-23 T 23-10-2018 IPR018076 Type II secretion system F domain A3L12_06220 c49a6cf9e74b6c04352d6acc71c6daa3 370 Pfam PF05763 Protein of unknown function (DUF835) 231 367 3.5E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_06470 1bf1ae7502d613b92fef52a2f198394c 235 Pfam PF01973 Protein of unknown function DUF115 52 185 1.2E-26 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A3L12_06470 1bf1ae7502d613b92fef52a2f198394c 235 SUPERFAMILY SSF63999 52 145 4.05E-8 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A3L12_06470 1bf1ae7502d613b92fef52a2f198394c 235 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.141 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 Gene3D G3DSA:3.30.1330.10 1 153 1.3E-42 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 161 314 6.7E-32 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 SUPERFAMILY SSF55326 3 152 4.71E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 SUPERFAMILY SSF56042 155 330 1.79E-46 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 2 336 5.9E-118 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 PIRSF PIRSF005644 1 336 1.2E-124 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 Gene3D G3DSA:3.90.650.10 154 336 2.1E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L12_01895 06268bfb1a32f19d049ad649ea758725 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 148 8.3E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L12_03710 0bf90934a2be1bb52c62de58b8919bd6 187 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 3 185 4.0E-84 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L12_03710 0bf90934a2be1bb52c62de58b8919bd6 187 SUPERFAMILY SSF55681 1 185 7.12E-72 T 23-10-2018 A3L12_03710 0bf90934a2be1bb52c62de58b8919bd6 187 Gene3D G3DSA:3.30.930.10 1 187 1.8E-70 T 23-10-2018 A3L12_03710 0bf90934a2be1bb52c62de58b8919bd6 187 Pfam PF04017 Domain of unknown function (DUF366) 1 184 3.2E-68 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L12_03710 0bf90934a2be1bb52c62de58b8919bd6 187 PIRSF PIRSF006503 1 187 9.6E-84 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L12_05545 927c59955380e04d6f39aa76b263f761 472 Gene3D G3DSA:3.90.1640.30 4 234 6.0E-17 T 23-10-2018 A3L12_05545 927c59955380e04d6f39aa76b263f761 472 SUPERFAMILY SSF64182 8 468 8.37E-64 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L12_05545 927c59955380e04d6f39aa76b263f761 472 Gene3D G3DSA:3.10.310.30 336 467 1.1E-9 T 23-10-2018 A3L12_05545 927c59955380e04d6f39aa76b263f761 472 Pfam PF02272 DHHA1 domain 343 464 3.3E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L12_05190 e7351dc520d0829bdcec9abd7a3ab2da 348 Gene3D G3DSA:3.90.550.10 31 247 2.0E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_05190 e7351dc520d0829bdcec9abd7a3ab2da 348 SUPERFAMILY SSF53448 36 263 1.22E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_05190 e7351dc520d0829bdcec9abd7a3ab2da 348 Pfam PF00535 Glycosyl transferase family 2 40 200 8.4E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 Gene3D G3DSA:4.10.990.10 4 53 3.7E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 4.6E-19 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.269 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 SUPERFAMILY SSF52080 5 147 2.35E-32 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L12_00705 5980fb111f5e7fbf6ffff0ed25cca164 148 Gene3D G3DSA:3.100.10.10 63 148 1.3E-21 T 23-10-2018 A3L12_04440 69e6c405d297ff7ca37d28928c766362 537 Gene3D G3DSA:3.60.21.10 313 521 1.0E-20 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_04440 69e6c405d297ff7ca37d28928c766362 537 Pfam PF00149 Calcineurin-like phosphoesterase 308 484 3.4E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_04440 69e6c405d297ff7ca37d28928c766362 537 SUPERFAMILY SSF56300 308 527 3.04E-34 T 23-10-2018 A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 SUPERFAMILY SSF46934 69 110 2.55E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 Gene3D G3DSA:2.20.70.30 10 69 6.0E-23 T 23-10-2018 IPR038187 NAC A/B domain superfamily A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 9.9E-39 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.783 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 Pfam PF01849 NAC domain 6 62 1.7E-11 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 SMART SM01407 6 66 6.8E-18 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L12_03995 bd3c15e7685271d842edc5630d9692b8 110 Gene3D G3DSA:1.10.8.10 70 109 1.7E-20 T 23-10-2018 A3L12_04445 4b8c0e1190df62c678416e5206a22116 121 Pfam PF07883 Cupin domain 38 104 1.5E-16 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L12_04445 4b8c0e1190df62c678416e5206a22116 121 Gene3D G3DSA:2.60.120.10 4 118 7.3E-33 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L12_04445 4b8c0e1190df62c678416e5206a22116 121 SUPERFAMILY SSF51182 9 105 5.17E-28 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L12_04015 b38363c7697adde5bbbbe72620869e88 185 SUPERFAMILY SSF53323 1 178 9.68E-57 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_04015 b38363c7697adde5bbbbe72620869e88 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 4.6E-42 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L12_04015 b38363c7697adde5bbbbe72620869e88 185 Gene3D G3DSA:3.40.920.10 1 183 2.5E-71 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_04015 b38363c7697adde5bbbbe72620869e88 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 6.9E-78 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A3L12_06515 ea5a05d517aeeb1b55c20402f5fdc843 562 SUPERFAMILY SSF51703 9 556 2.35E-229 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L12_06515 ea5a05d517aeeb1b55c20402f5fdc843 562 Gene3D G3DSA:3.20.20.240 1 562 3.5E-266 T 23-10-2018 A3L12_06515 ea5a05d517aeeb1b55c20402f5fdc843 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 1.3E-239 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L12_06515 ea5a05d517aeeb1b55c20402f5fdc843 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 3.1E-289 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L12_06345 7b37262b7602aafa3c122cf0bdc4f419 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06345 7b37262b7602aafa3c122cf0bdc4f419 264 Gene3D G3DSA:3.30.870.10 122 264 2.2E-74 T 23-10-2018 A3L12_06345 7b37262b7602aafa3c122cf0bdc4f419 264 SUPERFAMILY SSF46785 10 96 1.08E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06345 7b37262b7602aafa3c122cf0bdc4f419 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 78 1.3E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L12_02360 b45a28dd60f01a89cfb639b3620f7022 386 Gene3D G3DSA:3.50.50.60 12 359 6.3E-141 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02360 b45a28dd60f01a89cfb639b3620f7022 386 SUPERFAMILY SSF51905 10 377 1.1E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_02360 b45a28dd60f01a89cfb639b3620f7022 386 Pfam PF01266 FAD dependent oxidoreductase 11 355 2.4E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L12_02360 b45a28dd60f01a89cfb639b3620f7022 386 Gene3D G3DSA:3.30.9.10 88 315 6.3E-141 T 23-10-2018 A3L12_02360 b45a28dd60f01a89cfb639b3620f7022 386 SUPERFAMILY SSF54373 224 316 1.51E-9 T 23-10-2018 A3L12_02890 49b4a11d77668b3ea5d15f9085a584b9 59 Pfam PF01954 Protein of unknown function DUF104 1 56 3.1E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L12_02890 49b4a11d77668b3ea5d15f9085a584b9 59 Gene3D G3DSA:4.10.1150.10 1 58 3.9E-12 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L12_02890 49b4a11d77668b3ea5d15f9085a584b9 59 SUPERFAMILY SSF141694 1 57 2.43E-11 T 23-10-2018 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Gene3D G3DSA:3.40.50.970 389 547 7.6E-24 T 23-10-2018 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Gene3D G3DSA:3.30.70.20 552 613 2.2E-11 T 23-10-2018 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Pfam PF00037 4Fe-4S binding domain 584 606 1.8E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 194 2.4E-16 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 SUPERFAMILY SSF52518 355 540 8.83E-37 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Gene3D G3DSA:3.40.50.970 1 178 2.0E-54 T 23-10-2018 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 533 8.2E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 2 605 3.0E-216 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 PIRSF PIRSF006439 1 612 5.7E-217 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 SUPERFAMILY SSF52518 2 218 2.42E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 590 601 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 SUPERFAMILY SSF54862 552 610 2.97E-14 T 23-10-2018 A3L12_00430 cd0f85cb77e07e757f1e60f827443c19 613 SUPERFAMILY SSF52922 229 323 1.83E-8 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_02430 1d0891bb6fe38d0b870510a35258f323 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 18.583 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A3L12_02430 1d0891bb6fe38d0b870510a35258f323 507 SUPERFAMILY SSF82866 297 492 3.27E-24 T 23-10-2018 A3L12_02430 1d0891bb6fe38d0b870510a35258f323 507 Pfam PF02355 Protein export membrane protein 330 490 4.6E-18 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L12_02430 1d0891bb6fe38d0b870510a35258f323 507 Gene3D G3DSA:1.20.1640.10 310 501 2.2E-12 T 23-10-2018 A3L12_02430 1d0891bb6fe38d0b870510a35258f323 507 Gene3D G3DSA:3.30.70.3400 35 118 5.1E-8 T 23-10-2018 A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 Gene3D G3DSA:3.40.50.920 275 381 8.1E-24 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 258 3.4E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 Gene3D G3DSA:3.40.50.970 1 199 1.7E-84 T 23-10-2018 A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 8.3E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 SUPERFAMILY SSF52518 12 267 3.14E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_05330 d7146c1ec887676764cee1841b5e5d71 382 SUPERFAMILY SSF52922 274 378 1.14E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L12_02390 3390987d0a332d4bba16706ea1687a11 241 Pfam PF02080 TrkA-C domain 142 214 1.4E-13 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L12_02390 3390987d0a332d4bba16706ea1687a11 241 Gene3D G3DSA:3.30.70.1450 140 215 7.3E-17 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_02390 3390987d0a332d4bba16706ea1687a11 241 SUPERFAMILY SSF116726 128 212 4.45E-16 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L12_07810 52df86e3730291415ca38ef85560553c 293 Gene3D G3DSA:3.40.50.300 91 277 9.4E-9 T 23-10-2018 A3L12_07810 52df86e3730291415ca38ef85560553c 293 Pfam PF03477 ATP cone domain 11 86 1.2E-8 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L12_07810 52df86e3730291415ca38ef85560553c 293 SUPERFAMILY SSF52540 92 276 1.55E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07810 52df86e3730291415ca38ef85560553c 293 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 291 43.008 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A3L12_05400 1e37106a474f2f9982d306d46951b0cb 214 SUPERFAMILY SSF56300 1 206 2.92E-66 T 23-10-2018 A3L12_05400 1e37106a474f2f9982d306d46951b0cb 214 Gene3D G3DSA:3.60.21.10 1 213 1.7E-37 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_05400 1e37106a474f2f9982d306d46951b0cb 214 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 200 1.3E-19 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_04380 934507639fae3026f1e7ef339c538263 249 SUPERFAMILY SSF55681 1 247 1.37E-68 T 23-10-2018 A3L12_04380 934507639fae3026f1e7ef339c538263 249 Gene3D G3DSA:3.30.930.10 8 249 4.8E-63 T 23-10-2018 A3L12_04380 934507639fae3026f1e7ef339c538263 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 158 5.4E-13 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L12_05865 af21773b8fe2af1f63dcb248310ff124 166 Pfam PF01230 HIT domain 36 125 6.4E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L12_05865 af21773b8fe2af1f63dcb248310ff124 166 SUPERFAMILY SSF54197 1 156 2.65E-46 T 23-10-2018 IPR036265 HIT-like superfamily A3L12_05865 af21773b8fe2af1f63dcb248310ff124 166 Gene3D G3DSA:3.30.428.10 1 161 8.0E-58 T 23-10-2018 IPR036265 HIT-like superfamily A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 PIRSF PIRSF002741 193 412 4.7E-7 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 PIRSF PIRSF002741 93 196 0.0019 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 PIRSF PIRSF002741 425 696 5.4E-54 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 SUPERFAMILY SSF53850 113 192 3.8E-6 T 23-10-2018 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 Gene3D G3DSA:3.10.105.10 533 698 3.6E-42 T 23-10-2018 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 Gene3D G3DSA:3.40.190.10 429 531 6.1E-19 T 23-10-2018 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 SUPERFAMILY SSF53850 208 691 3.15E-82 T 23-10-2018 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 Gene3D G3DSA:3.90.76.10 220 412 8.6E-22 T 23-10-2018 A3L12_01195 1d79f0c6d47136ab473dbd0f226d497f 702 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 255 691 2.1E-65 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L12_04430 7ef79166d56039685b3f05b490fe4e23 224 SUPERFAMILY SSF109755 26 219 1.47E-20 T 23-10-2018 A3L12_04430 7ef79166d56039685b3f05b490fe4e23 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 2.8E-33 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L12_04430 7ef79166d56039685b3f05b490fe4e23 224 Pfam PF01865 Protein of unknown function DUF47 6 222 5.5E-43 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L12_04430 7ef79166d56039685b3f05b490fe4e23 224 Gene3D G3DSA:1.20.58.220 1 224 1.1E-48 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 Gene3D G3DSA:1.10.150.460 161 212 2.6E-37 T 23-10-2018 A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 SUPERFAMILY SSF89124 126 365 9.29E-79 T 23-10-2018 IPR036070 Nop domain superfamily A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 SMART SM00931 130 182 7.2E-26 T 23-10-2018 IPR012976 NOSIC A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 Gene3D G3DSA:1.10.246.90 245 368 1.0E-51 T 23-10-2018 A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 Gene3D G3DSA:3.30.420.220 1 125 1.2E-48 T 23-10-2018 A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 4.4E-70 T 23-10-2018 IPR002687 Nop domain A3L12_02270 a731b5dfd69163da6dc9f20d7582f065 415 Gene3D G3DSA:1.10.287.660 131 244 2.6E-37 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A3L12_02640 76ecf7992c4f22a1e63dce54517ece36 299 Gene3D G3DSA:1.10.3720.10 54 296 1.5E-56 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02640 76ecf7992c4f22a1e63dce54517ece36 299 SUPERFAMILY SSF161098 58 284 1.7E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02640 76ecf7992c4f22a1e63dce54517ece36 299 SUPERFAMILY SSF160964 6 43 3.01E-7 T 23-10-2018 A3L12_02640 76ecf7992c4f22a1e63dce54517ece36 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 284 1.0E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_06165 02411d3cacc7fa00db45960cf0ff2c4e 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 1.7E-8 T 23-10-2018 IPR001451 Hexapeptide repeat A3L12_06165 02411d3cacc7fa00db45960cf0ff2c4e 174 Gene3D G3DSA:2.160.10.10 1 172 3.9E-62 T 23-10-2018 A3L12_06165 02411d3cacc7fa00db45960cf0ff2c4e 174 SUPERFAMILY SSF51161 4 169 4.02E-50 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L12_00915 b42362c9b233447d7d4612c54dd15bf4 278 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 2.2E-94 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A3L12_00915 b42362c9b233447d7d4612c54dd15bf4 278 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L12_00915 b42362c9b233447d7d4612c54dd15bf4 278 Pfam PF01048 Phosphorylase superfamily 31 248 3.9E-43 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L12_00915 b42362c9b233447d7d4612c54dd15bf4 278 Gene3D G3DSA:3.40.50.1580 7 259 7.5E-83 T 23-10-2018 A3L12_00915 b42362c9b233447d7d4612c54dd15bf4 278 SUPERFAMILY SSF53167 18 247 4.19E-73 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L12_04595 9b04d1035fcfb1d8cd94129b411fc30d 162 Gene3D G3DSA:3.40.1520.10 1 162 5.4E-71 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L12_04595 9b04d1035fcfb1d8cd94129b411fc30d 162 Pfam PF04008 Adenosine specific kinase 7 160 1.2E-61 T 23-10-2018 IPR007153 Adenosine specific kinase A3L12_04595 9b04d1035fcfb1d8cd94129b411fc30d 162 SUPERFAMILY SSF103165 2 160 1.96E-60 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L12_07005 2ced52f49c2fef9437792cf7ba53e820 170 Pfam PF02632 BioY family 27 166 5.2E-37 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L12_07005 2ced52f49c2fef9437792cf7ba53e820 170 Gene3D G3DSA:1.10.1760.20 1 168 3.6E-52 T 23-10-2018 A3L12_07005 2ced52f49c2fef9437792cf7ba53e820 170 PIRSF PIRSF016661 1 169 2.6E-45 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L12_05780 42c30a9f5848d656271b8ecb09460345 153 PIRSF PIRSF018748 1 153 1.1E-55 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L12_05780 42c30a9f5848d656271b8ecb09460345 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 1.3E-32 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L12_03405 5481d87b3446d884ab1b83313ace5976 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.9E-28 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L12_03405 5481d87b3446d884ab1b83313ace5976 213 PIRSF PIRSF019202 1 213 4.6E-46 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 SMART SM00382 25 271 2.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01430 8ea81b706070e0026bb350de68f32943 344 Gene3D G3DSA:3.40.50.300 1 234 3.0E-70 T 23-10-2018 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 Gene3D G3DSA:2.40.50.140 246 343 9.0E-24 T 23-10-2018 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 Pfam PF03459 TOBE domain 281 343 1.4E-12 T 23-10-2018 IPR005116 Transport-associated OB, type 1 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 Pfam PF00005 ABC transporter 16 159 7.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 SUPERFAMILY SSF52540 1 237 6.52E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01430 8ea81b706070e0026bb350de68f32943 344 SUPERFAMILY SSF50331 243 344 3.69E-21 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L12_01430 8ea81b706070e0026bb350de68f32943 344 Gene3D G3DSA:2.40.50.100 268 339 9.0E-24 T 23-10-2018 A3L12_01430 8ea81b706070e0026bb350de68f32943 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_06150 fcfdbe34aa987c36d2e2228a4d50f183 255 Gene3D G3DSA:3.40.50.300 9 241 2.0E-53 T 23-10-2018 A3L12_07750 eb61d4b3e095d94fb6d0023091b0d709 222 SUPERFAMILY SSF53448 6 218 2.46E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_07750 eb61d4b3e095d94fb6d0023091b0d709 222 Gene3D G3DSA:3.90.550.10 2 221 8.1E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_07750 eb61d4b3e095d94fb6d0023091b0d709 222 Pfam PF00535 Glycosyl transferase family 2 8 167 2.6E-37 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_03560 088f98dabbe76324c1529963522dc545 247 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 227 3.8E-56 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L12_03560 088f98dabbe76324c1529963522dc545 247 Gene3D G3DSA:3.40.50.1000 4 223 1.8E-60 T 23-10-2018 IPR023214 HAD superfamily A3L12_03560 088f98dabbe76324c1529963522dc545 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 1.0E-27 T 23-10-2018 A3L12_03560 088f98dabbe76324c1529963522dc545 247 SUPERFAMILY SSF56784 1 231 7.2E-49 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_03560 088f98dabbe76324c1529963522dc545 247 Gene3D G3DSA:1.10.150.240 16 101 1.8E-60 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L12_03560 088f98dabbe76324c1529963522dc545 247 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 197 1.9E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03560 088f98dabbe76324c1529963522dc545 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.7E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03560 088f98dabbe76324c1529963522dc545 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.7E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03560 088f98dabbe76324c1529963522dc545 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.7E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 1.4E-95 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 SUPERFAMILY SSF51690 104 273 4.32E-47 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 SUPERFAMILY SSF54675 5 103 3.3E-30 T 23-10-2018 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 2.2E-49 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 Gene3D G3DSA:3.90.1170.20 10 271 8.3E-89 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 8.2E-32 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 Gene3D G3DSA:3.20.20.70 120 263 8.3E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03045 012d5827b9b2771b6bf9ef54ae7c9701 277 PIRSF PIRSF006250 2 276 1.2E-90 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A3L12_04985 3287c2ad5c8f71a2ee29db945c72ee3f 114 Gene3D G3DSA:2.60.120.10 10 106 1.3E-20 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L12_04985 3287c2ad5c8f71a2ee29db945c72ee3f 114 Pfam PF07883 Cupin domain 32 100 7.3E-16 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L12_04985 3287c2ad5c8f71a2ee29db945c72ee3f 114 SUPERFAMILY SSF51182 10 104 3.07E-23 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 SUPERFAMILY SSF53187 7 343 8.0E-42 T 23-10-2018 A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 SUPERFAMILY SSF55031 155 269 6.88E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 Gene3D G3DSA:3.40.630.10 15 336 2.9E-62 T 23-10-2018 A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 Gene3D G3DSA:3.30.70.360 155 264 2.9E-62 T 23-10-2018 A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 Pfam PF07687 Peptidase dimerisation domain 152 257 1.4E-9 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L12_07135 993ace3c1022077eebaa37f1a09750da 350 Pfam PF01546 Peptidase family M20/M25/M40 64 343 3.7E-24 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L12_07935 f5cc3f6ac4fadae194c1706f8663b338 276 SUPERFAMILY SSF81345 4 272 7.72E-18 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L12_07935 f5cc3f6ac4fadae194c1706f8663b338 276 Pfam PF00950 ABC 3 transport family 4 266 8.0E-29 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A3L12_01680 ed2a56e2663f14acc82d5ebe26e2244b 305 SUPERFAMILY SSF52540 13 224 1.15E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01680 ed2a56e2663f14acc82d5ebe26e2244b 305 SMART SM00382 38 211 1.2E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01680 ed2a56e2663f14acc82d5ebe26e2244b 305 Pfam PF00005 ABC transporter 29 164 4.3E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01680 ed2a56e2663f14acc82d5ebe26e2244b 305 Pfam PF13732 Domain of unknown function (DUF4162) 217 300 4.5E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L12_01680 ed2a56e2663f14acc82d5ebe26e2244b 305 Gene3D G3DSA:3.40.50.300 7 235 4.0E-66 T 23-10-2018 A3L12_07740 7ab92472b448ddd2252b4bc1d52c6185 141 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 1.8E-43 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L12_07740 7ab92472b448ddd2252b4bc1d52c6185 141 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 141 4.0E-34 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L12_07740 7ab92472b448ddd2252b4bc1d52c6185 141 SUPERFAMILY SSF69819 2 141 4.71E-47 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L12_07740 7ab92472b448ddd2252b4bc1d52c6185 141 Gene3D G3DSA:3.55.10.10 1 141 3.8E-51 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L12_07740 7ab92472b448ddd2252b4bc1d52c6185 141 Hamap MF_01222 Protein archease. 2 141 39.435 T 23-10-2018 IPR022952 Archease, archaea A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 Gene3D G3DSA:3.40.50.1950 18 188 5.9E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 Gene3D G3DSA:3.40.50.10300 189 402 1.0E-67 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 Pfam PF02441 Flavoprotein 19 188 1.1E-40 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 374 5.9E-55 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 SUPERFAMILY SSF102645 179 401 1.57E-63 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 SUPERFAMILY SSF52507 18 217 8.9E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L12_08040 3b75385c51d016461f7d7c9468967abc 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 398 2.4E-125 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 Pfam PF07687 Peptidase dimerisation domain 205 316 3.5E-18 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 Gene3D G3DSA:3.40.630.10 25 408 2.1E-74 T 23-10-2018 A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 413 4.8E-74 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 Gene3D G3DSA:3.30.70.360 208 340 2.1E-74 T 23-10-2018 A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 SUPERFAMILY SSF53187 6 418 8.3E-64 T 23-10-2018 A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 Pfam PF01546 Peptidase family M20/M25/M40 97 418 2.8E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L12_02605 1bd1498dfd6d777923cfc0bad6a549c5 420 SUPERFAMILY SSF55031 210 316 8.67E-17 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 SUPERFAMILY SSF102522 1 161 2.48E-52 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 PIRSF PIRSF006779 1 256 1.2E-74 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 7.6E-76 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 Gene3D G3DSA:2.40.30.90 161 256 5.4E-33 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 Gene3D G3DSA:3.40.50.10790 1 160 1.1E-58 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L12_03580 a8a41ea9b9c82128aa564e594de1727d 257 SUPERFAMILY SSF101852 163 254 3.92E-23 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L12_06980 7733dbc34ca4dd2f71432ae2c19632fa 273 Pfam PF01889 Membrane protein of unknown function DUF63 17 272 1.9E-73 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L12_03835 8d39c45afff419e9840335db8d08140e 243 Gene3D G3DSA:3.40.50.300 6 237 9.8E-64 T 23-10-2018 A3L12_03835 8d39c45afff419e9840335db8d08140e 243 SUPERFAMILY SSF52540 8 214 9.69E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03835 8d39c45afff419e9840335db8d08140e 243 Pfam PF00005 ABC transporter 18 155 6.6E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_03835 8d39c45afff419e9840335db8d08140e 243 SMART SM00382 27 202 1.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 1.0E-17 T 23-10-2018 A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 1.9E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 1.9E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 1.9E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 SUPERFAMILY SSF54862 3 65 3.89E-15 T 23-10-2018 A3L12_01250 923a9c4b15844a6bb100322d28a0ba7d 67 Gene3D G3DSA:3.30.70.20 2 67 1.6E-23 T 23-10-2018 A3L12_04315 2486b47315f95cdb4ffcbf5e3712fe56 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 1.5E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_04315 2486b47315f95cdb4ffcbf5e3712fe56 201 PIRSF PIRSF019239 29 201 7.2E-48 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_02815 59bab7ad0c1eb1ee69f88adea08d75a1 336 Pfam PF14258 Domain of unknown function (DUF4350) 36 104 2.8E-8 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 A3L12_05715 8611d0d6e43101471ab31696db4ebcbe 228 Gene3D G3DSA:3.30.70.3270 38 183 9.7E-25 T 23-10-2018 A3L12_05715 8611d0d6e43101471ab31696db4ebcbe 228 Pfam PF12838 4Fe-4S dicluster domain 59 113 8.2E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_05715 8611d0d6e43101471ab31696db4ebcbe 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_05715 8611d0d6e43101471ab31696db4ebcbe 228 SUPERFAMILY SSF54862 21 118 2.85E-22 T 23-10-2018 A3L12_07520 4a9bb37268f073db30a71ff8c773e482 249 Pfam PF13646 HEAT repeats 159 240 1.1E-6 T 23-10-2018 A3L12_07520 4a9bb37268f073db30a71ff8c773e482 249 SUPERFAMILY SSF48371 30 243 2.88E-20 T 23-10-2018 IPR016024 Armadillo-type fold A3L12_07520 4a9bb37268f073db30a71ff8c773e482 249 Gene3D G3DSA:1.25.10.10 1 249 1.5E-65 T 23-10-2018 IPR011989 Armadillo-like helical A3L12_01470 e3b0d822e149d47de6710976815002a1 365 SUPERFAMILY SSF53335 171 339 1.91E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01470 e3b0d822e149d47de6710976815002a1 365 Gene3D G3DSA:3.40.50.150 171 348 2.1E-26 T 23-10-2018 A3L12_01470 e3b0d822e149d47de6710976815002a1 365 Pfam PF01170 Putative RNA methylase family UPF0020 174 320 1.4E-10 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L12_01750 56d792fb157d9c0b24d29c8d119a564b 418 Pfam PF04895 Archaeal Nre, C-terminal 296 406 8.9E-39 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A3L12_01750 56d792fb157d9c0b24d29c8d119a564b 418 Hamap MF_02096 DNA repair protein. 2 406 40.299 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A3L12_01750 56d792fb157d9c0b24d29c8d119a564b 418 Pfam PF04894 Archaeal Nre, N-terminal 19 284 8.5E-102 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A3L12_08075 9a7e3ffee9bf1f5843e749a63bfca689 440 Gene3D G3DSA:3.30.2290.10 3 209 1.1E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L12_08075 9a7e3ffee9bf1f5843e749a63bfca689 440 SUPERFAMILY SSF111283 3 436 3.4E-93 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L12_08075 9a7e3ffee9bf1f5843e749a63bfca689 440 Pfam PF01523 Putative modulator of DNA gyrase 21 303 9.2E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L12_04625 a1920d0ff61e371bc02bb32f6590b524 87 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 87 8.3E-20 T 23-10-2018 A3L12_04625 a1920d0ff61e371bc02bb32f6590b524 87 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 87 2.1E-27 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L12_04625 a1920d0ff61e371bc02bb32f6590b524 87 Pfam PF02597 ThiS family 5 87 6.9E-23 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L12_04625 a1920d0ff61e371bc02bb32f6590b524 87 SUPERFAMILY SSF54285 2 85 9.65E-25 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L12_04625 a1920d0ff61e371bc02bb32f6590b524 87 Gene3D G3DSA:3.10.20.30 1 87 4.5E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_03920 983510f81747836c770f8536e0b3d46f 323 Gene3D G3DSA:1.10.8.300 205 314 8.1E-31 T 23-10-2018 A3L12_03920 983510f81747836c770f8536e0b3d46f 323 SUPERFAMILY SSF52540 7 289 2.06E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03920 983510f81747836c770f8536e0b3d46f 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 170 2.7E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L12_03920 983510f81747836c770f8536e0b3d46f 323 Gene3D G3DSA:3.40.50.300 21 187 3.9E-44 T 23-10-2018 A3L12_03920 983510f81747836c770f8536e0b3d46f 323 PIRSF PIRSF002849 1 319 3.6E-125 T 23-10-2018 A3L12_05650 a05572cde16f10283ef24b9b0c17fc49 166 PIRSF PIRSF004897 1 166 9.7E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L12_05650 a05572cde16f10283ef24b9b0c17fc49 166 SUPERFAMILY SSF55021 106 164 3.44E-8 T 23-10-2018 A3L12_05650 a05572cde16f10283ef24b9b0c17fc49 166 Gene3D G3DSA:3.30.70.260 104 165 7.8E-6 T 23-10-2018 A3L12_05650 a05572cde16f10283ef24b9b0c17fc49 166 Pfam PF01842 ACT domain 106 158 2.3E-6 T 23-10-2018 IPR002912 ACT domain A3L12_00575 75636b25423da8a9cd40e086b3618af1 390 Gene3D G3DSA:1.20.1250.20 1 195 5.0E-14 T 23-10-2018 A3L12_00575 75636b25423da8a9cd40e086b3618af1 390 Pfam PF07690 Major Facilitator Superfamily 13 307 6.0E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_00575 75636b25423da8a9cd40e086b3618af1 390 Gene3D G3DSA:1.20.1250.20 209 381 7.9E-9 T 23-10-2018 A3L12_00575 75636b25423da8a9cd40e086b3618af1 390 SUPERFAMILY SSF103473 11 382 2.22E-27 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_07815 6aa59e3ec1b4bdfa8bd0fc877c2931cc 434 Gene3D G3DSA:3.40.50.300 177 320 7.6E-6 T 23-10-2018 A3L12_07815 6aa59e3ec1b4bdfa8bd0fc877c2931cc 434 PIRSF PIRSF009445 2 433 6.2E-196 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L12_07815 6aa59e3ec1b4bdfa8bd0fc877c2931cc 434 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 3 434 49.47 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L12_06155 2210714b010b30aed07003c20ef2288b 224 Gene3D G3DSA:3.90.79.30 100 219 9.9E-58 T 23-10-2018 A3L12_06155 2210714b010b30aed07003c20ef2288b 224 Pfam PF15517 TBP-interacting protein N-terminus 3 101 9.2E-44 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A3L12_06155 2210714b010b30aed07003c20ef2288b 224 SUPERFAMILY SSF159612 2 217 2.62E-108 T 23-10-2018 A3L12_06155 2210714b010b30aed07003c20ef2288b 224 Gene3D G3DSA:3.40.1350.70 1 99 5.4E-46 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A3L12_03365 366bb9b9e7e5171dfe063dcc6783cbff 234 Pfam PF10086 Putative membrane peptidase family (DUF2324) 134 195 5.2E-7 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A3L12_03330 f8898ca6117142de24abb777ef6961e5 237 Gene3D G3DSA:3.40.50.300 5 234 4.8E-55 T 23-10-2018 A3L12_03330 f8898ca6117142de24abb777ef6961e5 237 Pfam PF06745 KaiC 13 234 1.6E-45 T 23-10-2018 IPR014774 KaiC-like domain A3L12_03330 f8898ca6117142de24abb777ef6961e5 237 SUPERFAMILY SSF52540 8 233 2.49E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 Pfam PF02834 LigT like Phosphoesterase 7 91 2.5E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 Pfam PF02834 LigT like Phosphoesterase 99 174 7.7E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.8E-53 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 Gene3D G3DSA:3.90.1140.10 1 184 1.3E-65 T 23-10-2018 A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 SUPERFAMILY SSF55144 1 182 6.98E-46 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A3L12_02735 d6ed253664d098546de10c1d511ffe0a 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 26.686 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 Pfam PF00005 ABC transporter 26 189 9.7E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 SMART SM00382 34 247 3.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 SUPERFAMILY SSF52540 34 323 2.33E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 Gene3D G3DSA:3.40.50.300 3 326 3.9E-99 T 23-10-2018 A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 1.8E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_01180 5a8ee8eefdee0d3187612f7ad5c37657 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 4.7E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L12_02690 faed95433d997006539147f9ce1bb580 351 Pfam PF05763 Protein of unknown function (DUF835) 230 349 9.7E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_03950 ec229194f4e39ba91011ea4441302c96 181 Gene3D G3DSA:3.40.50.620 42 181 2.7E-6 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_03950 ec229194f4e39ba91011ea4441302c96 181 SUPERFAMILY SSF52402 64 179 1.51E-6 T 23-10-2018 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 9.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 SMART SM00344 4 112 9.5E-26 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 Pfam PF01037 Lrp/AsnC ligand binding domain 78 144 1.4E-6 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 SUPERFAMILY SSF54909 66 149 6.7E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 SUPERFAMILY SSF46785 4 62 7.75E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 Gene3D G3DSA:1.10.10.10 2 55 1.4E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 Gene3D G3DSA:3.30.70.920 56 150 6.4E-12 T 23-10-2018 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 4.5E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 4.5E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_06970 0f6d7fdc27eb2f0fab5a747aefe98835 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 4.5E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 SMART SM00382 34 175 0.0069 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 1.6E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 Gene3D G3DSA:3.40.50.300 18 183 3.8E-48 T 23-10-2018 A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 Gene3D G3DSA:1.10.8.300 197 305 5.3E-32 T 23-10-2018 A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 SUPERFAMILY SSF52540 4 280 5.04E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02820 80b2ccccf0401e948ef6568db2e94dac 309 PIRSF PIRSF002849 1 309 1.6E-131 T 23-10-2018 A3L12_00730 d556116e49598ed773d285e6a5db06bc 186 SUPERFAMILY SSF52540 5 178 3.25E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00730 d556116e49598ed773d285e6a5db06bc 186 Gene3D G3DSA:3.40.50.300 2 177 1.8E-42 T 23-10-2018 A3L12_00730 d556116e49598ed773d285e6a5db06bc 186 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 6.4E-60 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L12_00730 d556116e49598ed773d285e6a5db06bc 186 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 46.749 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L12_00730 d556116e49598ed773d285e6a5db06bc 186 Pfam PF13189 Cytidylate kinase-like family 7 160 2.0E-23 T 23-10-2018 A3L12_07495 92bfcbebbac1d35b4bb908a0c55ff63b 231 Gene3D G3DSA:3.30.1330.130 9 175 1.5E-44 T 23-10-2018 A3L12_07495 92bfcbebbac1d35b4bb908a0c55ff63b 231 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 26 165 1.1E-38 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain A3L12_07495 92bfcbebbac1d35b4bb908a0c55ff63b 231 PIRSF PIRSF006578 5 212 2.4E-45 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E A3L12_07495 92bfcbebbac1d35b4bb908a0c55ff63b 231 SUPERFAMILY SSF143555 16 181 5.62E-45 T 23-10-2018 A3L12_00955 240a6f0e10de2b80deac6ea649907957 342 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L12_00955 240a6f0e10de2b80deac6ea649907957 342 Gene3D G3DSA:1.10.600.10 1 342 1.5E-132 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L12_00955 240a6f0e10de2b80deac6ea649907957 342 SUPERFAMILY SSF48576 4 342 9.03E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L12_00955 240a6f0e10de2b80deac6ea649907957 342 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L12_00955 240a6f0e10de2b80deac6ea649907957 342 Pfam PF00348 Polyprenyl synthetase 34 275 1.1E-70 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A3L12_05425 651e01f58995f57fdc93a329ff6e9837 194 Gene3D G3DSA:3.30.2170.10 150 193 7.4E-7 T 23-10-2018 A3L12_05425 651e01f58995f57fdc93a329ff6e9837 194 Gene3D G3DSA:3.30.2170.10 5 149 1.2E-34 T 23-10-2018 A3L12_05425 651e01f58995f57fdc93a329ff6e9837 194 Pfam PF04493 Endonuclease V 23 141 4.6E-30 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L12_05425 651e01f58995f57fdc93a329ff6e9837 194 Pfam PF04493 Endonuclease V 150 186 1.4E-4 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L12_00165 2fd51be4b73fa53c89bc2bbfb7b31a29 112 PIRSF PIRSF016134 2 111 3.3E-45 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L12_00165 2fd51be4b73fa53c89bc2bbfb7b31a29 112 SMART SM01022 6 109 3.3E-19 T 23-10-2018 IPR007374 ASCH domain A3L12_00165 2fd51be4b73fa53c89bc2bbfb7b31a29 112 Gene3D G3DSA:2.30.130.30 2 109 9.8E-43 T 23-10-2018 A3L12_00165 2fd51be4b73fa53c89bc2bbfb7b31a29 112 Pfam PF04266 ASCH domain 6 108 1.3E-16 T 23-10-2018 IPR007374 ASCH domain A3L12_00165 2fd51be4b73fa53c89bc2bbfb7b31a29 112 SUPERFAMILY SSF88697 1 109 1.21E-36 T 23-10-2018 IPR015947 PUA-like superfamily A3L12_01950 088693c4e1f7b56b7e524639f7f61048 306 SUPERFAMILY SSF53795 106 181 2.61E-5 T 23-10-2018 A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.435 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 SUPERFAMILY SSF54686 4 165 2.88E-54 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 Gene3D G3DSA:3.90.1170.10 1 178 5.1E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 PIRSF PIRSF005590 1 180 6.6E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00580 acf72ac7477a2fd82a5f8a1a55e5f32a 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 158 1.7E-31 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A3L12_07965 7a827012a4d5dff7dc3325066843e8a9 954 Gene3D G3DSA:3.40.50.12610 496 711 1.8E-85 T 23-10-2018 A3L12_07965 7a827012a4d5dff7dc3325066843e8a9 954 Gene3D G3DSA:2.60.40.3020 713 953 3.4E-106 T 23-10-2018 A3L12_07965 7a827012a4d5dff7dc3325066843e8a9 954 Gene3D G3DSA:2.60.40.3030 813 945 3.4E-106 T 23-10-2018 A3L12_07965 7a827012a4d5dff7dc3325066843e8a9 954 Gene3D G3DSA:2.40.128.390 603 670 1.8E-85 T 23-10-2018 A3L12_04305 775a12f5d4d5c1c7843dd9c610a8f24a 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 1.9E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_04305 775a12f5d4d5c1c7843dd9c610a8f24a 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 99 3.2E-30 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L12_06090 05f516c8fd892e216e1ac74f4aa22866 305 Gene3D G3DSA:3.40.50.300 1 236 1.5E-58 T 23-10-2018 A3L12_06090 05f516c8fd892e216e1ac74f4aa22866 305 Pfam PF13732 Domain of unknown function (DUF4162) 221 304 9.4E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L12_06090 05f516c8fd892e216e1ac74f4aa22866 305 SMART SM00382 26 224 3.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_06090 05f516c8fd892e216e1ac74f4aa22866 305 Pfam PF00005 ABC transporter 17 167 1.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06090 05f516c8fd892e216e1ac74f4aa22866 305 SUPERFAMILY SSF52540 2 229 1.02E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 Pfam PF04055 Radical SAM superfamily 67 252 1.4E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 Pfam PF08608 Wyosine base formation 255 315 1.1E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 SUPERFAMILY SSF102114 66 299 1.26E-15 T 23-10-2018 A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.224 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 16 314 1.4E-129 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L12_03240 62c1f1418302a5585f9012142421cb3b 332 Gene3D G3DSA:3.20.20.70 1 332 1.8E-129 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03540 f2731171efc74dc21a7e1ada2903c871 398 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 254 362 2.6E-29 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A3L12_03540 f2731171efc74dc21a7e1ada2903c871 398 Gene3D G3DSA:1.20.120.1220 52 169 7.9E-13 T 23-10-2018 A3L12_07770 b97848d31e4e75bdab27eb7a3ab90511 147 Gene3D G3DSA:3.40.50.1000 7 134 2.2E-9 T 23-10-2018 IPR023214 HAD superfamily A3L12_07770 b97848d31e4e75bdab27eb7a3ab90511 147 SUPERFAMILY SSF56784 11 128 1.46E-10 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_05840 9dd1ab05cf043e343435205cadb8b3e1 108 Gene3D G3DSA:1.10.10.1220 1 88 1.4E-41 T 23-10-2018 A3L12_06320 73e1731e74a1bc56a91a03e1ec8c81f7 250 SUPERFAMILY SSF55307 158 245 9.84E-12 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L12_06320 73e1731e74a1bc56a91a03e1ec8c81f7 250 Gene3D G3DSA:3.40.50.1440 114 248 3.2E-8 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L12_05910 4c28b31c9fdbe52f5c0069aef902106a 459 SUPERFAMILY SSF161070 78 376 9.02E-5 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 1.2E-23 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 2.0E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 SUPERFAMILY SSF82697 3 78 2.27E-22 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 2.5E-24 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 Gene3D G3DSA:3.30.1280.10 1 80 1.1E-26 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L12_03150 a2eb214c5f38c0e5ba0fe162ba40181e 81 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 19.125 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L12_06540 b40b55f393e2ee069f0511f0e75ecb60 205 Pfam PF00733 Asparagine synthase 8 69 6.3E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L12_06540 b40b55f393e2ee069f0511f0e75ecb60 205 Gene3D G3DSA:3.40.50.620 1 200 5.8E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_06540 b40b55f393e2ee069f0511f0e75ecb60 205 SUPERFAMILY SSF52402 4 153 4.19E-22 T 23-10-2018 A3L12_04775 2db337251e5d2b464d759fd64b772e20 240 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 7 230 2.8E-63 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A3L12_04775 2db337251e5d2b464d759fd64b772e20 240 Pfam PF09754 PAC2 family 17 220 1.3E-45 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L12_04775 2db337251e5d2b464d759fd64b772e20 240 Gene3D G3DSA:3.40.50.10900 2 240 4.9E-69 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L12_04775 2db337251e5d2b464d759fd64b772e20 240 SUPERFAMILY SSF159659 9 229 1.96E-45 T 23-10-2018 A3L12_07850 977632944396d883d3a57873be4a3a24 76 SUPERFAMILY SSF54285 1 76 1.87E-9 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L12_07850 977632944396d883d3a57873be4a3a24 76 Gene3D G3DSA:3.10.20.30 1 76 1.1E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_07850 977632944396d883d3a57873be4a3a24 76 Pfam PF02597 ThiS family 8 76 1.8E-7 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L12_05320 a24a1aff8d7482306113fd6751d41929 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 7.0E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_05320 a24a1aff8d7482306113fd6751d41929 284 Gene3D G3DSA:3.40.50.970 69 266 4.5E-33 T 23-10-2018 A3L12_05320 a24a1aff8d7482306113fd6751d41929 284 SUPERFAMILY SSF52518 19 272 2.09E-78 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_07585 86321691cc64dc70b3594d003373c898 314 SUPERFAMILY SSF53335 128 299 3.47E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_07585 86321691cc64dc70b3594d003373c898 314 Pfam PF13847 Methyltransferase domain 152 263 1.5E-13 T 23-10-2018 IPR025714 Methyltransferase domain A3L12_07585 86321691cc64dc70b3594d003373c898 314 Gene3D G3DSA:3.40.50.150 134 311 4.3E-24 T 23-10-2018 A3L12_00560 2faab2a876bc72dcbc40cf42c31e6471 303 SUPERFAMILY SSF55681 7 299 4.1E-55 T 23-10-2018 A3L12_00560 2faab2a876bc72dcbc40cf42c31e6471 303 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 295 5.3E-43 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L12_00560 2faab2a876bc72dcbc40cf42c31e6471 303 Gene3D G3DSA:3.30.930.10 1 302 6.2E-74 T 23-10-2018 A3L12_05230 41684e1a6ab933de0aa874c80ff2f800 283 SUPERFAMILY SSF54534 3 155 2.36E-42 T 23-10-2018 A3L12_05230 41684e1a6ab933de0aa874c80ff2f800 283 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 7.4E-18 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L12_05230 41684e1a6ab933de0aa874c80ff2f800 283 Gene3D G3DSA:3.10.50.80 2 165 5.8E-53 T 23-10-2018 A3L12_02835 e6b583e0c48872c60466f839a8733cb3 750 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 22 497 1.1E-8 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 A3L12_02835 e6b583e0c48872c60466f839a8733cb3 750 Gene3D G3DSA:3.40.50.12610 458 571 6.4E-15 T 23-10-2018 A3L12_04290 ef4bc8d8b432057d7ab2cf385fe5299b 140 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 127 2.8E-27 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L12_02930 03dec30c19b739a7c3eac7cc61e92dbd 137 SUPERFAMILY SSF81593 5 129 1.49E-40 T 23-10-2018 A3L12_02930 03dec30c19b739a7c3eac7cc61e92dbd 137 Pfam PF05168 HEPN domain 7 129 1.4E-30 T 23-10-2018 IPR007842 HEPN domain A3L12_02930 03dec30c19b739a7c3eac7cc61e92dbd 137 SMART SM00748 11 123 4.0E-40 T 23-10-2018 IPR007842 HEPN domain A3L12_02930 03dec30c19b739a7c3eac7cc61e92dbd 137 Gene3D G3DSA:1.20.120.330 2 131 7.7E-36 T 23-10-2018 A3L12_03280 acdb5377d58ab063142f6dd667ea7622 340 Pfam PF17231 Family of unknown function (DUF5305) 123 328 2.8E-11 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L12_01120 caa2823af1b10e45096f15542492ef96 222 SUPERFAMILY SSF159071 42 101 4.58E-5 T 23-10-2018 A3L12_02865 9f22400324964484982e6540ed1dcc79 247 Pfam PF01925 Sulfite exporter TauE/SafE 6 239 1.9E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 SUPERFAMILY SSF53383 32 440 8.26E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 Gene3D G3DSA:3.40.640.10 71 339 7.9E-147 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 Pfam PF00202 Aminotransferase class-III 33 437 4.0E-111 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 PIRSF PIRSF000521 2 143 5.6E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 PIRSF PIRSF000521 131 442 9.3E-52 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L12_04555 d354dd702c37256b9260288aac1b3f78 444 Gene3D G3DSA:3.90.1150.10 14 437 7.9E-147 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L12_08105 afe4fa461938ceccff71e8e95835713a 547 Pfam PF08308 PEGA domain 357 420 2.7E-9 T 23-10-2018 IPR013229 PEGA A3L12_08105 afe4fa461938ceccff71e8e95835713a 547 Pfam PF08308 PEGA domain 427 481 3.2E-12 T 23-10-2018 IPR013229 PEGA A3L12_06435 60933c753febb761a6e0362ff12d5450 221 Pfam PF01966 HD domain 18 186 5.4E-13 T 23-10-2018 IPR006674 HD domain A3L12_06435 60933c753febb761a6e0362ff12d5450 221 Gene3D G3DSA:1.10.3210.30 1 176 6.1E-19 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L12_06435 60933c753febb761a6e0362ff12d5450 221 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 18 152 6.7E-12 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A3L12_07725 fcd8ea46ab145c600b515f0a3b1bf148 479 Gene3D G3DSA:3.90.1860.10 1 479 5.0E-225 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L12_07725 fcd8ea46ab145c600b515f0a3b1bf148 479 SUPERFAMILY SSF103365 3 479 4.45E-185 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L12_07725 fcd8ea46ab145c600b515f0a3b1bf148 479 Pfam PF01139 tRNA-splicing ligase RtcB 45 479 1.1E-181 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L12_01620 acb081ac087a959309737c61ae25e094 440 Gene3D G3DSA:1.20.1250.20 223 424 8.3E-24 T 23-10-2018 A3L12_01620 acb081ac087a959309737c61ae25e094 440 SUPERFAMILY SSF103473 8 423 5.36E-62 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_01620 acb081ac087a959309737c61ae25e094 440 Pfam PF07690 Major Facilitator Superfamily 12 279 1.7E-34 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_01620 acb081ac087a959309737c61ae25e094 440 Gene3D G3DSA:1.20.1250.20 2 196 2.8E-30 T 23-10-2018 A3L12_02725 c931b3ce45e2e45281a9ea3f328b2994 574 SUPERFAMILY SSF88713 5 219 6.0E-15 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_01500 348d716222de45e6d8fce61e20fb18ab 283 Gene3D G3DSA:1.10.3720.10 2 272 7.6E-44 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_01500 348d716222de45e6d8fce61e20fb18ab 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 269 2.2E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_01500 348d716222de45e6d8fce61e20fb18ab 283 SUPERFAMILY SSF161098 3 276 2.49E-45 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_05755 767a7c359acd6449493c247c4a87ffbf 187 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 167 186 5.0E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L12_05755 767a7c359acd6449493c247c4a87ffbf 187 SUPERFAMILY SSF52833 16 108 7.18E-12 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L12_05755 767a7c359acd6449493c247c4a87ffbf 187 Gene3D G3DSA:3.40.30.10 14 116 9.0E-8 T 23-10-2018 A3L12_07540 afa235a365077ede8c6b290c57bb07e0 543 Gene3D G3DSA:3.40.50.300 262 539 3.9E-90 T 23-10-2018 A3L12_07540 afa235a365077ede8c6b290c57bb07e0 543 SUPERFAMILY SSF52540 144 526 2.99E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_07540 afa235a365077ede8c6b290c57bb07e0 543 Gene3D G3DSA:3.30.450.370 49 259 2.1E-55 T 23-10-2018 A3L12_07540 afa235a365077ede8c6b290c57bb07e0 543 Pfam PF00437 Type II/IV secretion system protein 164 408 6.0E-48 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L12_07540 afa235a365077ede8c6b290c57bb07e0 543 Gene3D G3DSA:1.10.390.40 81 161 2.1E-55 T 23-10-2018 A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 Gene3D G3DSA:1.10.3720.10 4 264 5.5E-64 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 Gene3D G3DSA:1.10.3720.10 286 540 1.3E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 SUPERFAMILY SSF161098 288 536 7.52E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 363 534 9.9E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 254 1.5E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_00310 9b545297793932da72a3e20a4e127cdd 543 SUPERFAMILY SSF161098 3 258 1.21E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 SUPERFAMILY SSF53448 218 423 1.2E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 6.0E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 6.0E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 6.0E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 SUPERFAMILY SSF56784 3 216 1.12E-36 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 Gene3D G3DSA:1.10.150.240 18 80 9.4E-28 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 Pfam PF00535 Glycosyl transferase family 2 220 346 8.6E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 Gene3D G3DSA:3.40.50.1000 6 184 9.4E-28 T 23-10-2018 IPR023214 HAD superfamily A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 Gene3D G3DSA:3.90.550.10 201 439 1.0E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_03650 6192e177daad9bf80fd9f07e31b26e67 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 183 1.6E-21 T 23-10-2018 A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 353 7.2E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 SMART SM00418 366 444 2.3E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 Gene3D G3DSA:1.10.10.10 359 444 8.1E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 SUPERFAMILY SSF53686 3 359 7.99E-73 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 Gene3D G3DSA:3.40.50.1100 49 358 9.6E-96 T 23-10-2018 A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 Gene3D G3DSA:3.40.50.1100 96 192 9.6E-96 T 23-10-2018 A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 SUPERFAMILY SSF46785 373 442 8.77E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_01065 decf919ec4261164a41348b8f5d23fdf 444 Pfam PF03551 Transcriptional regulator PadR-like family 377 440 3.1E-8 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L12_01090 d763f5e1219c058944d9004e5b4724d4 111 Pfam PF00120 Glutamine synthetase, catalytic domain 9 63 1.8E-11 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L12_01090 d763f5e1219c058944d9004e5b4724d4 111 SUPERFAMILY SSF55931 7 75 7.65E-10 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L12_01090 d763f5e1219c058944d9004e5b4724d4 111 Gene3D G3DSA:3.30.590.10 3 76 4.2E-13 T 23-10-2018 A3L12_04405 d7daa21ad5bd6a1ceae33e5f35774071 282 SUPERFAMILY SSF53335 81 264 5.97E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_04405 d7daa21ad5bd6a1ceae33e5f35774071 282 Gene3D G3DSA:3.40.50.150 116 280 2.9E-24 T 23-10-2018 A3L12_04405 d7daa21ad5bd6a1ceae33e5f35774071 282 Pfam PF08241 Methyltransferase domain 130 233 1.1E-10 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L12_05135 73b2588fed64c5ff645016af2fcb17bf 174 SUPERFAMILY SSF89028 3 165 6.28E-50 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L12_05135 73b2588fed64c5ff645016af2fcb17bf 174 Gene3D G3DSA:1.20.1200.10 24 172 1.5E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L12_05135 73b2588fed64c5ff645016af2fcb17bf 174 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 165 8.0E-53 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L12_05135 73b2588fed64c5ff645016af2fcb17bf 174 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 170 9.7E-60 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L12_05135 73b2588fed64c5ff645016af2fcb17bf 174 Pfam PF01923 Cobalamin adenosyltransferase 3 159 8.4E-50 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L12_01395 ec17a46f32a447e1b70817f28f06743f 388 SUPERFAMILY SSF51905 2 381 1.04E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01395 ec17a46f32a447e1b70817f28f06743f 388 Pfam PF01266 FAD dependent oxidoreductase 4 355 2.5E-75 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L12_01395 ec17a46f32a447e1b70817f28f06743f 388 Gene3D G3DSA:3.50.50.60 4 359 1.3E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L12_01395 ec17a46f32a447e1b70817f28f06743f 388 Gene3D G3DSA:3.30.9.10 82 317 1.3E-118 T 23-10-2018 A3L12_01395 ec17a46f32a447e1b70817f28f06743f 388 SUPERFAMILY SSF54373 225 318 1.96E-7 T 23-10-2018 A3L12_05075 011ace277a197ae2e0f7bcf6ae82d3d2 456 Pfam PF01554 MatE 241 407 7.1E-36 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_05075 011ace277a197ae2e0f7bcf6ae82d3d2 456 Pfam PF01554 MatE 17 177 1.0E-35 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_05075 011ace277a197ae2e0f7bcf6ae82d3d2 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 418 6.2E-119 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_05075 011ace277a197ae2e0f7bcf6ae82d3d2 456 PIRSF PIRSF006603 5 456 1.4E-104 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L12_04400 90529b5d9415270fe51effe25292c2d3 311 Gene3D G3DSA:3.20.20.140 1 311 3.2E-91 T 23-10-2018 A3L12_04400 90529b5d9415270fe51effe25292c2d3 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 5.2E-91 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L12_04400 90529b5d9415270fe51effe25292c2d3 311 SUPERFAMILY SSF51556 1 310 3.32E-74 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L12_05345 0eb0d727ce512d18e838680133c426d1 153 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 2.6E-15 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A3L12_05345 0eb0d727ce512d18e838680133c426d1 153 Gene3D G3DSA:2.60.120.1140 1 124 1.3E-10 T 23-10-2018 IPR038695 Saro_0823-like superfamily A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 51 70 2.4E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 2.4E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 92 108 2.4E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 71 88 2.4E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 7 29 2.4E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 SMART SM00562 4 144 8.8E-83 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 4 142 36.013 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 Gene3D G3DSA:3.30.70.141 1 157 5.6E-70 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 Pfam PF00334 Nucleoside diphosphate kinase 5 142 3.7E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_07090 2997dd78de8691bbbc010e6d7fe6556a 170 SUPERFAMILY SSF54919 4 151 8.25E-61 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L12_04355 2c0bb27b2106f574df8567a6d812ade5 186 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 180 2.4E-48 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L12_04355 2c0bb27b2106f574df8567a6d812ade5 186 SMART SM01007 7 181 1.6E-59 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L12_04355 2c0bb27b2106f574df8567a6d812ade5 186 Gene3D G3DSA:3.40.225.10 3 186 1.4E-62 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L12_04355 2c0bb27b2106f574df8567a6d812ade5 186 SUPERFAMILY SSF53639 6 184 6.47E-57 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L12_01160 0b53061a3e9b97672fbd96b6f743bca5 185 Gene3D G3DSA:3.40.50.300 2 183 1.9E-41 T 23-10-2018 A3L12_01160 0b53061a3e9b97672fbd96b6f743bca5 185 SUPERFAMILY SSF52540 1 182 3.55E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_01160 0b53061a3e9b97672fbd96b6f743bca5 185 Pfam PF13207 AAA domain 6 136 3.0E-18 T 23-10-2018 A3L12_01160 0b53061a3e9b97672fbd96b6f743bca5 185 Hamap MF_01111 UPF0200 protein . 2 182 32.193 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A3L12_07255 5c425d88abba46130969293985b4081b 153 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 7.4E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L12_07255 5c425d88abba46130969293985b4081b 153 Gene3D G3DSA:3.30.420.130 1 113 2.2E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_07255 5c425d88abba46130969293985b4081b 153 SUPERFAMILY SSF53146 1 112 2.49E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 Pfam PF00227 Proteasome subunit 33 214 2.3E-64 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.158 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 2.8E-105 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 SUPERFAMILY SSF56235 7 242 2.44E-81 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_00445 0ed26c820d2064febbcf4f59312a4dc9 260 Gene3D G3DSA:3.60.20.10 5 253 7.4E-90 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_04490 77e50eb0895c02e48f76a4469d70b728 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 116 8.4E-26 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L12_04680 9807efdb5173c2adc3b975428e5e3f25 172 SUPERFAMILY SSF142913 3 170 1.1E-50 T 23-10-2018 A3L12_04680 9807efdb5173c2adc3b975428e5e3f25 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 4.4E-65 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A3L12_04680 9807efdb5173c2adc3b975428e5e3f25 172 Gene3D G3DSA:3.30.930.10 1 170 4.4E-61 T 23-10-2018 A3L12_06300 0780678a57a51722459ace17a1232607 170 SUPERFAMILY SSF54814 55 96 7.85E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_06300 0780678a57a51722459ace17a1232607 170 Pfam PF13184 NusA-like KH domain 57 124 2.9E-9 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A3L12_06300 0780678a57a51722459ace17a1232607 170 Gene3D G3DSA:3.30.300.20 45 97 6.2E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_02665 24ec781fbf0e2436197641ec24684175 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.2E-21 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L12_02665 24ec781fbf0e2436197641ec24684175 120 Gene3D G3DSA:3.30.70.3250 1 120 1.5E-47 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L12_02665 24ec781fbf0e2436197641ec24684175 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.233 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L12_02665 24ec781fbf0e2436197641ec24684175 120 PIRSF PIRSF004952 4 120 2.2E-45 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A3L12_02665 24ec781fbf0e2436197641ec24684175 120 SUPERFAMILY SSF160350 4 117 7.59E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L12_04660 334ed239a29260a94829db6527e7db4d 175 PIRSF PIRSF006707 1 173 1.6E-37 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A3L12_04660 334ed239a29260a94829db6527e7db4d 175 SUPERFAMILY SSF46785 4 128 1.92E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04660 334ed239a29260a94829db6527e7db4d 175 Pfam PF01047 MarR family 38 81 7.1E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L12_04660 334ed239a29260a94829db6527e7db4d 175 Gene3D G3DSA:1.10.10.10 2 86 1.2E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_01925 fa9e1c305a372661599f9e111cadd420 426 SUPERFAMILY SSF53335 12 91 7.24E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01925 fa9e1c305a372661599f9e111cadd420 426 SUPERFAMILY SSF53335 247 426 3.52E-10 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01925 fa9e1c305a372661599f9e111cadd420 426 Pfam PF01555 DNA methylase 29 86 5.3E-9 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A3L12_01925 fa9e1c305a372661599f9e111cadd420 426 SUPERFAMILY SSF53335 39 271 4.35E-14 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_01925 fa9e1c305a372661599f9e111cadd420 426 Gene3D G3DSA:3.40.50.150 2 118 4.4E-17 T 23-10-2018 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 SUPERFAMILY SSF47954 108 199 1.24E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 4.6E-22 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.1E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 SUPERFAMILY SSF57783 4 50 5.53E-17 T 23-10-2018 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Pfam PF08271 TFIIB zinc-binding 6 47 3.2E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Gene3D G3DSA:1.10.472.10 207 299 1.7E-28 T 23-10-2018 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Gene3D G3DSA:1.10.472.170 6 197 2.5E-66 T 23-10-2018 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 SMART SM00385 210 291 3.8E-13 T 23-10-2018 IPR013763 Cyclin-like A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 SMART SM00385 114 195 4.2E-12 T 23-10-2018 IPR013763 Cyclin-like A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 SUPERFAMILY SSF47954 206 298 1.63E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 1.8E-60 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L12_06565 a4d9d8adc202a5b2e7242cf4a8d957b2 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.251 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L12_03880 b4d1efe99bca82940252d3e0119ccd2d 194 Gene3D G3DSA:1.10.1760.20 1 193 6.8E-19 T 23-10-2018 A3L12_00210 34b70c050a66b27255dc0f7b413f7dd5 232 SUPERFAMILY SSF56784 3 223 1.05E-36 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_00210 34b70c050a66b27255dc0f7b413f7dd5 232 Gene3D G3DSA:3.40.50.1000 3 217 6.4E-35 T 23-10-2018 IPR023214 HAD superfamily A3L12_00210 34b70c050a66b27255dc0f7b413f7dd5 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 189 3.4E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L12_00210 34b70c050a66b27255dc0f7b413f7dd5 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 7.0E-18 T 23-10-2018 A3L12_00210 34b70c050a66b27255dc0f7b413f7dd5 232 Gene3D G3DSA:1.10.150.520 14 96 6.4E-35 T 23-10-2018 A3L12_03085 2c696dc7740dab976598aa473260f54f 425 Gene3D G3DSA:3.20.20.540 45 362 4.6E-136 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L12_03085 2c696dc7740dab976598aa473260f54f 425 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 3.0E-187 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L12_03085 2c696dc7740dab976598aa473260f54f 425 Pfam PF01964 Radical SAM ThiC family 2 420 1.3E-181 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L12_03085 2c696dc7740dab976598aa473260f54f 425 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 86.667 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L12_07130 9f88597914eef310f3d125933d963d41 231 SUPERFAMILY SSF56281 9 225 1.76E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_07130 9f88597914eef310f3d125933d963d41 231 Pfam PF00753 Metallo-beta-lactamase superfamily 26 212 7.7E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_07130 9f88597914eef310f3d125933d963d41 231 Gene3D G3DSA:3.60.15.10 3 226 1.8E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_07130 9f88597914eef310f3d125933d963d41 231 SMART SM00849 25 212 5.5E-39 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_02440 460595e58aa31b63dd9b39c815933bbb 103 Gene3D G3DSA:1.20.5.620 32 91 8.6E-6 T 23-10-2018 A3L12_02440 460595e58aa31b63dd9b39c815933bbb 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 88 3.1E-17 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A3L12_02440 460595e58aa31b63dd9b39c815933bbb 103 SUPERFAMILY SSF81573 36 89 3.14E-6 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L12_05830 264bc17d81f57ef478458764fbd3417f 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 1.5E-26 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A3L12_05830 264bc17d81f57ef478458764fbd3417f 110 Gene3D G3DSA:3.30.300.100 1 110 4.9E-36 T 23-10-2018 IPR035954 MTH677-like superfamily A3L12_04605 b220323dca19acd30916b10e8c1d24ac 314 SUPERFAMILY SSF102114 73 284 2.35E-11 T 23-10-2018 A3L12_04605 b220323dca19acd30916b10e8c1d24ac 314 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 220 300 3.1E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L12_04605 b220323dca19acd30916b10e8c1d24ac 314 Pfam PF13186 Iron-sulfur cluster-binding domain 223 279 4.9E-6 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L12_04605 b220323dca19acd30916b10e8c1d24ac 314 Gene3D G3DSA:3.20.20.70 195 312 1.8E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04115 b4d91b3df3e44103cc6f505f404c38ad 375 SUPERFAMILY SSF111249 6 372 2.75E-174 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L12_04115 b4d91b3df3e44103cc6f505f404c38ad 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 8.7E-184 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L12_04115 b4d91b3df3e44103cc6f505f404c38ad 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 60.927 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L12_04115 b4d91b3df3e44103cc6f505f404c38ad 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L12_04115 b4d91b3df3e44103cc6f505f404c38ad 375 PIRSF PIRSF015647 5 375 3.7E-187 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L12_04510 f07a475ddca88e107abf9f15c370c657 175 SUPERFAMILY SSF143243 6 160 1.96E-31 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04510 f07a475ddca88e107abf9f15c370c657 175 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 151 3.0E-15 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04510 f07a475ddca88e107abf9f15c370c657 175 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 151 2.4E-22 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04510 f07a475ddca88e107abf9f15c370c657 175 Gene3D G3DSA:3.30.460.80 14 134 3.1E-17 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_07880 28c8d5f01c12aa6d758696f102dd8b99 255 Pfam PF13559 Domain of unknown function (DUF4129) 185 243 3.1E-8 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L12_01865 2eee8a83d928cdb9097aef7113892bed 137 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 1.4E-26 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L12_01865 2eee8a83d928cdb9097aef7113892bed 137 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.159 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L12_01865 2eee8a83d928cdb9097aef7113892bed 137 PIRSF PIRSF004761 1 137 1.7E-33 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L12_01865 2eee8a83d928cdb9097aef7113892bed 137 Gene3D G3DSA:2.20.28.10 69 123 1.5E-26 T 23-10-2018 A3L12_01865 2eee8a83d928cdb9097aef7113892bed 137 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A3L12_04505 47d0d5c07f8b7fbd4fe6a7b5fc6ec587 170 Gene3D G3DSA:3.40.50.12280 8 170 9.3E-51 T 23-10-2018 A3L12_04505 47d0d5c07f8b7fbd4fe6a7b5fc6ec587 170 SUPERFAMILY SSF56770 34 164 8.24E-52 T 23-10-2018 A3L12_04505 47d0d5c07f8b7fbd4fe6a7b5fc6ec587 170 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 4.4E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 SUPERFAMILY SSF52042 5 126 7.85E-45 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 3 125 6.0E-58 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 SMART SM01393 18 125 1.4E-59 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.293 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L12_00680 884538e40c2ef029a5abe52a2b095cbb 127 Pfam PF01655 Ribosomal protein L32 18 125 2.2E-39 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_04155 62842a367b5cf40005982cf5b4a11471 278 Gene3D G3DSA:3.90.226.10 56 264 1.4E-22 T 23-10-2018 A3L12_04155 62842a367b5cf40005982cf5b4a11471 278 Pfam PF01972 Serine dehydrogenase proteinase 9 273 3.7E-144 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A3L12_04155 62842a367b5cf40005982cf5b4a11471 278 SUPERFAMILY SSF52096 13 239 3.79E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L12_06115 f37855427ba4a40d399d5ebe87835acd 338 Pfam PF01343 Peptidase family S49 148 297 6.3E-40 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A3L12_06115 f37855427ba4a40d399d5ebe87835acd 338 Gene3D G3DSA:3.90.226.10 92 291 1.7E-53 T 23-10-2018 A3L12_06115 f37855427ba4a40d399d5ebe87835acd 338 Gene3D G3DSA:3.40.1750.20 188 254 1.7E-53 T 23-10-2018 A3L12_06115 f37855427ba4a40d399d5ebe87835acd 338 SUPERFAMILY SSF52096 84 283 8.7E-35 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L12_06115 f37855427ba4a40d399d5ebe87835acd 338 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 90 293 5.8E-68 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A3L12_05100 1d0c1bf0ca77414fd0273c414bae7841 167 Pfam PF04167 Protein of unknown function (DUF402) 55 120 4.5E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L12_05100 1d0c1bf0ca77414fd0273c414bae7841 167 SUPERFAMILY SSF159234 2 161 1.44E-36 T 23-10-2018 IPR035930 FomD-like superfamily A3L12_05100 1d0c1bf0ca77414fd0273c414bae7841 167 Gene3D G3DSA:2.40.380.10 17 163 7.5E-12 T 23-10-2018 IPR035930 FomD-like superfamily A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 Gene3D G3DSA:3.30.1200.10 1 95 2.2E-32 T 23-10-2018 IPR036591 YggU-like superfamily A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 95 21.54 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 SUPERFAMILY SSF69786 3 93 5.23E-30 T 23-10-2018 IPR036591 YggU-like superfamily A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 SMART SM01152 8 83 4.6E-36 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 5 90 3.8E-29 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A3L12_05105 af5a13e0cade78a4186b60977bcf7709 95 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 81 1.6E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L12_04930 ec501525f99641271a7dc57bd5b61763 370 PIRSF PIRSF018978 1 370 1.8E-163 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A3L12_06545 a4bddf69d3832a20e1530b1d15279d3b 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 3.0E-34 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L12_06545 a4bddf69d3832a20e1530b1d15279d3b 138 SMART SM01103 5 92 2.5E-26 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L12_06545 a4bddf69d3832a20e1530b1d15279d3b 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 5.5E-13 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L12_06545 a4bddf69d3832a20e1530b1d15279d3b 138 SUPERFAMILY SSF75471 5 101 3.14E-18 T 23-10-2018 IPR035920 YhbY-like superfamily A3L12_06545 a4bddf69d3832a20e1530b1d15279d3b 138 Gene3D G3DSA:3.30.110.60 4 111 1.1E-19 T 23-10-2018 IPR035920 YhbY-like superfamily A3L12_01795 8a009a08de7a5c52e0830e73d81f5ba9 265 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 6 264 7.7E-75 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A3L12_01795 8a009a08de7a5c52e0830e73d81f5ba9 265 Gene3D G3DSA:3.40.50.10900 1 244 3.0E-74 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L12_01795 8a009a08de7a5c52e0830e73d81f5ba9 265 SUPERFAMILY SSF159659 3 252 4.84E-43 T 23-10-2018 A3L12_01795 8a009a08de7a5c52e0830e73d81f5ba9 265 Pfam PF09754 PAC2 family 19 242 8.8E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L12_05465 3a9f188d5ca09f345eaf04fa50104672 368 Pfam PF01497 Periplasmic binding protein 106 323 4.0E-38 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L12_05465 3a9f188d5ca09f345eaf04fa50104672 368 SUPERFAMILY SSF53807 91 352 1.06E-70 T 23-10-2018 A3L12_05465 3a9f188d5ca09f345eaf04fa50104672 368 Gene3D G3DSA:3.40.50.1980 222 347 1.7E-34 T 23-10-2018 A3L12_05465 3a9f188d5ca09f345eaf04fa50104672 368 Gene3D G3DSA:3.40.50.1980 88 218 1.1E-31 T 23-10-2018 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 343 23.132 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 Gene3D G3DSA:3.90.920.10 9 326 7.2E-118 T 23-10-2018 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 Gene3D G3DSA:1.10.8.160 176 277 7.2E-118 T 23-10-2018 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 SUPERFAMILY SSF56747 6 341 3.49E-89 T 23-10-2018 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 328 5.5E-55 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L12_02575 e3cec3a91f8fac0199f03d075cb236e8 351 Pfam PF01896 DNA primase small subunit 96 306 9.1E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L12_04955 e4a0bf596466bdfc7f855b2b3e3c1346 248 SUPERFAMILY SSF102114 16 197 4.58E-25 T 23-10-2018 A3L12_04955 e4a0bf596466bdfc7f855b2b3e3c1346 248 Pfam PF13353 4Fe-4S single cluster domain 18 113 9.5E-12 T 23-10-2018 A3L12_04955 e4a0bf596466bdfc7f855b2b3e3c1346 248 Gene3D G3DSA:3.20.20.70 3 194 4.3E-28 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_04955 e4a0bf596466bdfc7f855b2b3e3c1346 248 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 183 1.1E-56 T 23-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein A3L12_04955 e4a0bf596466bdfc7f855b2b3e3c1346 248 Pfam PF04055 Radical SAM superfamily 26 179 9.2E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_07060 e8f1965be3bbc240be6356cbd6425f2f 319 Pfam PF12802 MarR family 265 308 1.4E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L12_07060 e8f1965be3bbc240be6356cbd6425f2f 319 Gene3D G3DSA:1.10.10.10 243 319 5.7E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_07060 e8f1965be3bbc240be6356cbd6425f2f 319 SUPERFAMILY SSF46785 265 318 2.7E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_04375 72b3b19f4b299aa3372b42d37a29092c 207 SUPERFAMILY SSF111278 2 183 4.58E-49 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_04375 72b3b19f4b299aa3372b42d37a29092c 207 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.072 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L12_04375 72b3b19f4b299aa3372b42d37a29092c 207 Gene3D G3DSA:3.30.1960.10 1 194 5.9E-49 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_04375 72b3b19f4b299aa3372b42d37a29092c 207 Pfam PF02676 Methyltransferase TYW3 3 184 2.1E-39 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L12_06795 b9ab9097b526ab1b204c12384486da65 202 SUPERFAMILY SSF144091 9 193 2.62E-36 T 23-10-2018 A3L12_06795 b9ab9097b526ab1b204c12384486da65 202 Gene3D G3DSA:1.20.1540.10 3 197 1.8E-33 T 23-10-2018 IPR035952 Rhomboid-like superfamily A3L12_06795 b9ab9097b526ab1b204c12384486da65 202 Pfam PF01694 Rhomboid family 55 190 2.7E-27 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A3L12_04045 fc9840f92ae9e728e61b091eee9a32fe 331 Gene3D G3DSA:3.40.50.970 12 97 7.1E-11 T 23-10-2018 A3L12_04045 fc9840f92ae9e728e61b091eee9a32fe 331 Gene3D G3DSA:3.40.50.970 98 323 2.0E-67 T 23-10-2018 A3L12_04045 fc9840f92ae9e728e61b091eee9a32fe 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 1.7E-24 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_04045 fc9840f92ae9e728e61b091eee9a32fe 331 SUPERFAMILY SSF52518 12 318 2.55E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_04905 f4ae67d2e2f70f4538150f1197f53f62 219 Gene3D G3DSA:3.40.50.620 6 137 3.4E-17 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_04905 f4ae67d2e2f70f4538150f1197f53f62 219 SUPERFAMILY SSF52402 8 214 6.47E-47 T 23-10-2018 A3L12_04905 f4ae67d2e2f70f4538150f1197f53f62 219 Gene3D G3DSA:3.90.1490.10 138 214 4.2E-8 T 23-10-2018 A3L12_04905 f4ae67d2e2f70f4538150f1197f53f62 219 Pfam PF01902 Diphthamide synthase 8 213 2.5E-28 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L12_05010 c7fe0264ae098f9eb54beb741655e193 177 Gene3D G3DSA:3.40.50.1950 1 177 2.9E-74 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L12_05010 c7fe0264ae098f9eb54beb741655e193 177 SUPERFAMILY SSF52507 1 176 4.19E-60 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L12_05010 c7fe0264ae098f9eb54beb741655e193 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 4.7E-73 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L12_05010 c7fe0264ae098f9eb54beb741655e193 177 Pfam PF02441 Flavoprotein 1 156 2.7E-28 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L12_05010 c7fe0264ae098f9eb54beb741655e193 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.677 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L12_03575 9f7ec0d6711ea3c24adf2df5ff4e1dfe 534 Gene3D G3DSA:3.10.620.30 266 405 4.2E-7 T 23-10-2018 A3L12_03575 9f7ec0d6711ea3c24adf2df5ff4e1dfe 534 Pfam PF01841 Transglutaminase-like superfamily 292 388 5.8E-8 T 23-10-2018 IPR002931 Transglutaminase-like A3L12_03575 9f7ec0d6711ea3c24adf2df5ff4e1dfe 534 SUPERFAMILY SSF54001 273 443 7.85E-10 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L12_05845 443d139094ddae72400404efb55e1552 375 Gene3D G3DSA:1.25.40.10 4 347 9.9E-54 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_05845 443d139094ddae72400404efb55e1552 375 SUPERFAMILY SSF48452 50 340 1.83E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_05845 443d139094ddae72400404efb55e1552 375 SMART SM00028 105 138 18.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_05845 443d139094ddae72400404efb55e1552 375 SMART SM00028 65 98 20.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L12_02685 dcebc4fdab5335c905c7f1d4147402bb 396 Pfam PF04165 Protein of unknown function (DUF401) 7 389 1.0E-61 T 23-10-2018 IPR007294 Protein of unknown function DUF401 A3L12_02685 dcebc4fdab5335c905c7f1d4147402bb 396 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 6 392 6.3E-128 T 23-10-2018 IPR005253 Conserved hypothetical protein CHP00529 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 2.9E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Gene3D G3DSA:3.40.980.10 179 320 1.2E-111 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_06600 d34da329bd576b261e870316b4e78788 400 SMART SM00852 184 321 1.7E-35 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_06600 d34da329bd576b261e870316b4e78788 400 SUPERFAMILY SSF63882 7 180 1.2E-54 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_06600 d34da329bd576b261e870316b4e78788 400 SUPERFAMILY SSF53218 181 325 6.15E-41 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L12_06600 d34da329bd576b261e870316b4e78788 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 2.1E-42 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Gene3D G3DSA:3.90.105.10 26 178 1.2E-111 T 23-10-2018 A3L12_06600 d34da329bd576b261e870316b4e78788 400 SUPERFAMILY SSF63867 331 399 2.49E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Gene3D G3DSA:2.40.340.10 329 400 1.3E-25 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Gene3D G3DSA:2.170.190.11 49 145 1.2E-111 T 23-10-2018 A3L12_06600 d34da329bd576b261e870316b4e78788 400 Pfam PF00994 Probable molybdopterin binding domain 186 320 6.7E-22 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_06600 d34da329bd576b261e870316b4e78788 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 1.8E-30 T 23-10-2018 IPR001453 MoaB/Mog domain A3L12_05040 a447556e3b66b84d37660836bfeb3244 261 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 21 173 7.9E-7 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L12_05040 a447556e3b66b84d37660836bfeb3244 261 PIRSF PIRSF036670 1 261 5.5E-113 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A3L12_05040 a447556e3b66b84d37660836bfeb3244 261 SUPERFAMILY SSF52402 21 185 8.6E-32 T 23-10-2018 A3L12_05040 a447556e3b66b84d37660836bfeb3244 261 Gene3D G3DSA:3.40.50.620 19 190 3.3E-27 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 Gene3D G3DSA:3.90.79.10 40 167 9.0E-42 T 23-10-2018 A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 Pfam PF00293 NUDIX domain 49 164 7.7E-24 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 SUPERFAMILY SSF55811 35 166 7.18E-35 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 PRINTS PR00502 NUDIX hydrolase family signature 70 84 8.1E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L12_02070 3255b3fdc2ecf4f29bf67bf16e8b8099 167 PRINTS PR00502 NUDIX hydrolase family signature 84 99 8.1E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L12_00255 7e5687f7a7587af6da0497ead2bd4d04 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 1.6E-65 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L12_00255 7e5687f7a7587af6da0497ead2bd4d04 380 Gene3D G3DSA:1.20.1530.20 1 380 7.3E-96 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_02745 08359fa2574d07d2bcee3ebc677874f7 204 Pfam PF00005 ABC transporter 21 159 1.9E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_02745 08359fa2574d07d2bcee3ebc677874f7 204 SUPERFAMILY SSF52540 21 189 5.45E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_02745 08359fa2574d07d2bcee3ebc677874f7 204 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_02745 08359fa2574d07d2bcee3ebc677874f7 204 Gene3D G3DSA:3.40.50.300 2 197 3.3E-35 T 23-10-2018 A3L12_00500 4e2b4c4b3ae3a3c988bb4748b4da9e05 151 SUPERFAMILY SSF51230 75 150 2.09E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L12_00500 4e2b4c4b3ae3a3c988bb4748b4da9e05 151 Gene3D G3DSA:2.40.50.100 76 151 5.3E-30 T 23-10-2018 A3L12_00500 4e2b4c4b3ae3a3c988bb4748b4da9e05 151 Pfam PF00364 Biotin-requiring enzyme 85 150 1.6E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L12_00500 4e2b4c4b3ae3a3c988bb4748b4da9e05 151 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 107 124 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L12_02295 144c6a913d0f0a68aacbd339a4503f79 280 SUPERFAMILY SSF102114 6 212 4.19E-16 T 23-10-2018 A3L12_02295 144c6a913d0f0a68aacbd339a4503f79 280 SMART SM00729 18 225 6.1E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_02295 144c6a913d0f0a68aacbd339a4503f79 280 Gene3D G3DSA:3.80.30.30 56 250 9.3E-12 T 23-10-2018 A3L12_02295 144c6a913d0f0a68aacbd339a4503f79 280 Pfam PF04055 Radical SAM superfamily 23 187 8.4E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_00130 08c64705abef98fcc968b1fdf3f204cd 275 Pfam PF13559 Domain of unknown function (DUF4129) 202 265 2.5E-8 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 7 147 24.682 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 Gene3D G3DSA:1.10.8.50 1 75 4.5E-23 T 23-10-2018 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 PIRSF PIRSF002134 1 148 8.3E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 Pfam PF00416 Ribosomal protein S13/S18 9 136 6.0E-39 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 3 147 1.1E-59 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 ProSitePatterns PS00646 Ribosomal protein S13 signature. 116 129 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 Gene3D G3DSA:4.10.910.10 88 137 4.4E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L12_00755 bc021905d9e7573e3d29a80b0efe3c7b 148 SUPERFAMILY SSF46946 8 143 4.71E-33 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L12_06460 a64795715acf1e6af13290010c7337c7 248 SMART SM00849 37 214 1.1E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_06460 a64795715acf1e6af13290010c7337c7 248 Gene3D G3DSA:3.60.15.10 2 248 4.5E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_06460 a64795715acf1e6af13290010c7337c7 248 Pfam PF12706 Beta-lactamase superfamily domain 49 215 2.6E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L12_06460 a64795715acf1e6af13290010c7337c7 248 SUPERFAMILY SSF56281 3 246 1.7E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L12_07395 eaf6d365e060fe0702cb718407bf478d 147 SUPERFAMILY SSF47240 5 141 2.96E-8 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_07395 eaf6d365e060fe0702cb718407bf478d 147 Pfam PF02915 Rubrerythrin 7 141 2.5E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07395 eaf6d365e060fe0702cb718407bf478d 147 Gene3D G3DSA:1.20.1260.10 2 144 5.2E-8 T 23-10-2018 IPR012347 Ferritin-like A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 201 4.4E-73 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 2.4E-65 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 SUPERFAMILY SSF50891 88 218 1.25E-46 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 Gene3D G3DSA:2.40.100.10 87 226 8.7E-60 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 SUPERFAMILY SSF160467 5 92 5.49E-21 T 23-10-2018 A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 Gene3D G3DSA:3.30.1360.40 5 76 3.5E-24 T 23-10-2018 A3L12_04645 4d3b685e26991705bd6237a66a5b1e36 231 SMART SM00796 3 202 2.9E-104 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L12_02405 8cf3c05528df0d2121e8870ffefc786e 168 Gene3D G3DSA:2.30.130.10 95 166 8.7E-19 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L12_02405 8cf3c05528df0d2121e8870ffefc786e 168 Gene3D G3DSA:3.10.450.220 1 94 1.2E-43 T 23-10-2018 A3L12_02405 8cf3c05528df0d2121e8870ffefc786e 168 Pfam PF03657 Uncharacterised protein family (UPF0113) 8 166 4.6E-10 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A3L12_04975 d4ef99a7d48d3ee2d56be4e6e850f39c 441 Pfam PF01523 Putative modulator of DNA gyrase 14 304 6.4E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L12_04975 d4ef99a7d48d3ee2d56be4e6e850f39c 441 SUPERFAMILY SSF111283 2 439 1.57E-91 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L12_04975 d4ef99a7d48d3ee2d56be4e6e850f39c 441 Gene3D G3DSA:3.30.2290.10 1 206 3.9E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L12_01095 b22509cb34074e219f4ed77457409435 285 Gene3D G3DSA:3.20.20.370 52 284 6.5E-13 T 23-10-2018 A3L12_01095 b22509cb34074e219f4ed77457409435 285 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 71 279 1.4E-31 T 23-10-2018 IPR018763 Protein of unknown function DUF2334 A3L12_01095 b22509cb34074e219f4ed77457409435 285 SUPERFAMILY SSF88713 68 282 2.92E-13 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L12_06785 558cd5e85f66f5ebbdfb939f3f80f410 270 Pfam PF01889 Membrane protein of unknown function DUF63 4 269 2.5E-82 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L12_04090 5b79294bbe9e95bede14e349cc1a3d90 195 Hamap MF_00582 UPF0215 protein . 9 189 33.974 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L12_04090 5b79294bbe9e95bede14e349cc1a3d90 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 9.0E-44 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L12_04090 5b79294bbe9e95bede14e349cc1a3d90 195 PIRSF PIRSF006380 1 195 5.2E-71 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L12_04090 5b79294bbe9e95bede14e349cc1a3d90 195 Gene3D G3DSA:3.30.2170.10 3 195 1.9E-60 T 23-10-2018 A3L12_04090 5b79294bbe9e95bede14e349cc1a3d90 195 Pfam PF01949 Protein of unknown function DUF99 8 188 4.4E-65 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L12_05565 e673bdf7f2ce1ba90d934093d182ef67 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 9.4E-146 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A3L12_06270 5a52823ec5645f8285012b805710539f 382 SUPERFAMILY SSF53187 5 380 1.57E-87 T 23-10-2018 A3L12_06270 5a52823ec5645f8285012b805710539f 382 Pfam PF07687 Peptidase dimerisation domain 184 272 6.7E-8 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L12_06270 5a52823ec5645f8285012b805710539f 382 Gene3D G3DSA:3.30.70.360 176 290 2.6E-142 T 23-10-2018 A3L12_06270 5a52823ec5645f8285012b805710539f 382 Gene3D G3DSA:3.40.630.10 14 365 2.6E-142 T 23-10-2018 A3L12_06270 5a52823ec5645f8285012b805710539f 382 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 1.4E-119 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L12_06270 5a52823ec5645f8285012b805710539f 382 Pfam PF01546 Peptidase family M20/M25/M40 68 376 4.3E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L12_06270 5a52823ec5645f8285012b805710539f 382 SUPERFAMILY SSF55031 177 285 4.71E-30 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L12_06270 5a52823ec5645f8285012b805710539f 382 PIRSF PIRSF005962 1 382 4.2E-131 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L12_02120 d814f0280c6b8b40639df1e2efa2a36c 135 SUPERFAMILY SSF143870 12 127 4.32E-23 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L12_02120 d814f0280c6b8b40639df1e2efa2a36c 135 Pfam PF08617 Kinase binding protein CGI-121 41 99 7.6E-5 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 A3L12_02120 d814f0280c6b8b40639df1e2efa2a36c 135 Gene3D G3DSA:3.30.2380.10 6 135 8.3E-44 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L12_04520 09b9a2f1c08a0d98b06e8ceb8bf8205c 329 Pfam PF00146 NADH dehydrogenase 11 319 4.1E-61 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_07795 663e6274d0a14c14c64bfbdbb8fb6441 263 SUPERFAMILY SSF56235 2 256 2.65E-14 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_07795 663e6274d0a14c14c64bfbdbb8fb6441 263 Pfam PF13522 Glutamine amidotransferase domain 82 165 2.8E-6 T 23-10-2018 A3L12_07795 663e6274d0a14c14c64bfbdbb8fb6441 263 Gene3D G3DSA:3.60.20.10 33 260 7.8E-12 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 9.1E-29 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 PIRSF PIRSF004985 1 126 1.3E-37 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 Gene3D G3DSA:3.40.1350.10 2 129 8.4E-38 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 SUPERFAMILY SSF52980 3 106 3.22E-27 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 126 6.0E-31 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L12_06170 f41cbf2af039cb50b5278beb3d641d2d 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 35.966 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L12_03450 a4d73d1b657a56c1760ae3c28e4e1793 57 Pfam PF03911 Sec61beta family 11 51 1.7E-16 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L12_03450 a4d73d1b657a56c1760ae3c28e4e1793 57 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 14.903 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A3L12_00745 cbd2ccaee2fb08863dcbf291a604f65a 195 SUPERFAMILY SSF53335 6 190 3.67E-43 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_00745 cbd2ccaee2fb08863dcbf291a604f65a 195 Pfam PF05175 Methyltransferase small domain 27 191 5.4E-45 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L12_00745 cbd2ccaee2fb08863dcbf291a604f65a 195 Gene3D G3DSA:3.40.50.150 5 193 9.9E-51 T 23-10-2018 A3L12_04280 799c9b201144261bdc4112600dd1a237 507 Pfam PF00361 Proton-conducting membrane transporter 121 396 3.1E-49 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_04280 799c9b201144261bdc4112600dd1a237 507 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 297 309 3.4E-5 T 23-10-2018 A3L12_04280 799c9b201144261bdc4112600dd1a237 507 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 207 228 3.4E-5 T 23-10-2018 A3L12_04280 799c9b201144261bdc4112600dd1a237 507 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 72 97 3.4E-5 T 23-10-2018 A3L12_04940 142c3ba986f9a74d830dd670146127e3 202 Gene3D G3DSA:3.40.109.10 1 201 1.0E-44 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L12_04940 142c3ba986f9a74d830dd670146127e3 202 SUPERFAMILY SSF55469 1 201 3.01E-41 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L12_04940 142c3ba986f9a74d830dd670146127e3 202 Pfam PF00881 Nitroreductase family 9 181 1.5E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 16 140 9.1E-61 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 SUPERFAMILY SSF50193 16 141 4.06E-44 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.0E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 Gene3D G3DSA:2.40.150.20 1 140 5.9E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.502 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L12_00645 bf71f3d66ad4f2b2b1aa6d0eb5bebc28 141 SMART SM01374 20 141 3.2E-56 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L12_01475 1fac937d150b7203268c64b428d7f131 143 SUPERFAMILY SSF51735 7 139 1.46E-44 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L12_01475 1fac937d150b7203268c64b428d7f131 143 Pfam PF13380 CoA binding domain 23 137 1.3E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_01475 1fac937d150b7203268c64b428d7f131 143 Gene3D G3DSA:3.40.50.720 4 143 5.6E-49 T 23-10-2018 A3L12_01475 1fac937d150b7203268c64b428d7f131 143 SMART SM00881 19 111 1.2E-27 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L12_02545 2d28352bda88ac6d20fe2a9bf802a089 285 Gene3D G3DSA:1.10.3730.20 198 279 2.3E-5 T 23-10-2018 A3L12_02545 2d28352bda88ac6d20fe2a9bf802a089 285 SUPERFAMILY SSF103481 38 140 2.75E-13 T 23-10-2018 A3L12_02545 2d28352bda88ac6d20fe2a9bf802a089 285 SUPERFAMILY SSF103481 180 278 9.68E-19 T 23-10-2018 A3L12_02545 2d28352bda88ac6d20fe2a9bf802a089 285 Pfam PF00892 EamA-like transporter family 146 273 1.6E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_02545 2d28352bda88ac6d20fe2a9bf802a089 285 Pfam PF00892 EamA-like transporter family 3 137 3.6E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_06085 0bb1372cb57be40f4508249c22d54ef1 421 Gene3D G3DSA:3.40.1670.10 296 408 7.7E-38 T 23-10-2018 A3L12_06085 0bb1372cb57be40f4508249c22d54ef1 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 385 1.2E-97 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L12_06085 0bb1372cb57be40f4508249c22d54ef1 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 409 1.0E-113 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L12_06085 0bb1372cb57be40f4508249c22d54ef1 421 SUPERFAMILY SSF143968 282 419 5.89E-42 T 23-10-2018 A3L12_06085 0bb1372cb57be40f4508249c22d54ef1 421 SUPERFAMILY SSF50475 6 279 1.02E-62 T 23-10-2018 A3L12_05440 e80cc2951fcd2757a3ad7f5a93a372a0 68 Gene3D G3DSA:2.30.30.240 2 68 1.6E-6 T 23-10-2018 A3L12_05440 e80cc2951fcd2757a3ad7f5a93a372a0 68 Pfam PF05239 PRC-barrel domain 2 67 1.4E-10 T 23-10-2018 IPR027275 PRC-barrel domain A3L12_05440 e80cc2951fcd2757a3ad7f5a93a372a0 68 SUPERFAMILY SSF50346 1 65 2.75E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L12_03250 ea24160faa226fb8c9963015a79e8d99 50 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 4 49 19.805 T 23-10-2018 IPR022845 Ribosomal protein S27ae A3L12_03250 ea24160faa226fb8c9963015a79e8d99 50 Gene3D G3DSA:2.20.25.660 2 49 8.1E-19 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L12_03250 ea24160faa226fb8c9963015a79e8d99 50 SMART SM01402 4 46 3.7E-24 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L12_03250 ea24160faa226fb8c9963015a79e8d99 50 Pfam PF01599 Ribosomal protein S27a 5 46 9.7E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L12_03250 ea24160faa226fb8c9963015a79e8d99 50 SUPERFAMILY SSF57829 4 49 8.42E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_03295 44cbc80d959c913098c52015709aaaa0 170 Pfam PF06510 Protein of unknown function (DUF1102) 47 169 2.1E-26 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L12_00525 d0fe6cf48c42b216cbe4efadb7da5f75 164 Gene3D G3DSA:1.20.58.2050 1 164 6.7E-79 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L12_00525 d0fe6cf48c42b216cbe4efadb7da5f75 164 Pfam PF05916 GINS complex protein 28 147 1.2E-5 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A3L12_00635 fc304f5b477df30b609610adf44712a0 88 SUPERFAMILY SSF101744 3 87 2.27E-23 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A3L12_00635 fc304f5b477df30b609610adf44712a0 88 SMART SM00538 1 88 7.3E-26 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L12_00635 fc304f5b477df30b609610adf44712a0 88 Pfam PF01868 Domain of unknown function UPF0086 5 84 1.4E-18 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L12_00635 fc304f5b477df30b609610adf44712a0 88 Gene3D G3DSA:2.30.30.210 1 88 5.6E-31 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A3L12_00635 fc304f5b477df30b609610adf44712a0 88 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 8 83 18.571 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A3L12_04030 e1e531f3da1e8b08907b1bea26b20786 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 6.7E-20 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_04030 e1e531f3da1e8b08907b1bea26b20786 311 SUPERFAMILY SSF52518 16 308 2.23E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_04030 e1e531f3da1e8b08907b1bea26b20786 311 Gene3D G3DSA:3.40.50.970 102 310 1.3E-68 T 23-10-2018 A3L12_05695 8cd698026e861db594be201320fa17a0 309 Pfam PF00146 NADH dehydrogenase 8 306 2.2E-54 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_01590 e06ad78723018101b1721898645522f7 429 SUPERFAMILY SSF161070 11 357 2.48E-9 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L12_01105 f10b0cb2b17f114db6a5b0b7b7c4059d 467 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 220 4.6E-17 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L12_04340 969401bbd61bafecf08fb412825fd036 481 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 30 361 2.5E-151 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L12_04340 969401bbd61bafecf08fb412825fd036 481 PIRSF PIRSF016666 1 481 4.3E-233 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L12_04340 969401bbd61bafecf08fb412825fd036 481 Gene3D G3DSA:2.130.10.10 27 295 4.7E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L12_04340 969401bbd61bafecf08fb412825fd036 481 SUPERFAMILY SSF50998 84 224 1.1E-7 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L12_02695 44cda94dece54526f69fa07c66eceb9c 274 SUPERFAMILY SSF103481 176 269 9.94E-11 T 23-10-2018 A3L12_02695 44cda94dece54526f69fa07c66eceb9c 274 SUPERFAMILY SSF103481 39 133 2.09E-13 T 23-10-2018 A3L12_02695 44cda94dece54526f69fa07c66eceb9c 274 Pfam PF00892 EamA-like transporter family 139 268 4.8E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_02695 44cda94dece54526f69fa07c66eceb9c 274 Pfam PF00892 EamA-like transporter family 4 131 6.2E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_03680 76d2f87f3f905be06099fff89eaa332e 319 Pfam PF04055 Radical SAM superfamily 36 193 3.1E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_03680 76d2f87f3f905be06099fff89eaa332e 319 Gene3D G3DSA:3.20.20.70 18 240 8.6E-23 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_03680 76d2f87f3f905be06099fff89eaa332e 319 SUPERFAMILY SSF102114 19 287 9.16E-35 T 23-10-2018 A3L12_03680 76d2f87f3f905be06099fff89eaa332e 319 SMART SM00729 27 238 7.4E-17 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L12_00835 42f3a1ad62630a192c1f925a19233b3f 99 Pfam PF04930 FUN14 family 12 96 8.0E-12 T 23-10-2018 IPR007014 FUN14 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 73 5.5E-7 T 23-10-2018 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 140 220 1.9E-18 T 23-10-2018 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 5 220 3.2E-73 T 23-10-2018 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 Hamap MF_01419 Phosphoglycolate phosphatase. 4 230 31.844 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 SUPERFAMILY SSF56784 2 226 1.58E-39 T 23-10-2018 IPR036412 HAD-like superfamily A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 Gene3D G3DSA:3.40.50.1000 5 223 3.8E-72 T 23-10-2018 IPR023214 HAD superfamily A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 Gene3D G3DSA:3.90.1070.10 87 154 3.8E-72 T 23-10-2018 A3L12_06275 c008e62de19c4d22f5e741faed96e936 239 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 7 233 1.8E-68 T 23-10-2018 A3L12_03810 eca496bb4b77985bba5b8cd3bc6af81f 434 Gene3D G3DSA:3.30.110.80 238 333 1.7E-121 T 23-10-2018 A3L12_03810 eca496bb4b77985bba5b8cd3bc6af81f 434 SUPERFAMILY SSF56300 1 337 1.24E-63 T 23-10-2018 A3L12_03810 eca496bb4b77985bba5b8cd3bc6af81f 434 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 241 1.8E-14 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L12_03810 eca496bb4b77985bba5b8cd3bc6af81f 434 Gene3D G3DSA:3.60.21.10 1 280 1.7E-121 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_03810 eca496bb4b77985bba5b8cd3bc6af81f 434 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 399 23.847 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L12_07410 079256b1758166f8acfd88f18d172ab9 117 SUPERFAMILY SSF117916 16 59 5.23E-6 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_07410 079256b1758166f8acfd88f18d172ab9 117 Gene3D G3DSA:3.30.300.130 11 97 5.0E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L12_07410 079256b1758166f8acfd88f18d172ab9 117 Pfam PF01883 Iron-sulfur cluster assembly protein 15 57 1.5E-6 T 23-10-2018 IPR002744 MIP18 family-like A3L12_06375 05ad9c943256914b426efc24c94bddb8 264 PIRSF PIRSF005054 1 243 1.0E-63 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_06375 05ad9c943256914b426efc24c94bddb8 264 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 238 2.9E-47 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_06375 05ad9c943256914b426efc24c94bddb8 264 Gene3D G3DSA:3.30.70.1890 1 122 2.5E-37 T 23-10-2018 A3L12_06375 05ad9c943256914b426efc24c94bddb8 264 Pfam PF01881 CRISPR associated protein Cas6 95 238 3.3E-32 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L12_06375 05ad9c943256914b426efc24c94bddb8 264 Gene3D G3DSA:3.30.70.1900 123 241 1.4E-34 T 23-10-2018 A3L12_04265 c91fde6b1e90abb05ea70a3cec8fdd72 230 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_04265 c91fde6b1e90abb05ea70a3cec8fdd72 230 SMART SM00382 28 216 2.2E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04265 c91fde6b1e90abb05ea70a3cec8fdd72 230 SUPERFAMILY SSF52540 3 215 4.1E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04265 c91fde6b1e90abb05ea70a3cec8fdd72 230 Pfam PF00005 ABC transporter 20 157 2.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_04265 c91fde6b1e90abb05ea70a3cec8fdd72 230 Gene3D G3DSA:3.40.50.300 1 221 3.7E-59 T 23-10-2018 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 PRINTS PR00446 Hydrogen uptake protein signature 13 25 3.1E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 PRINTS PR00446 Hydrogen uptake protein signature 25 36 3.1E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 PRINTS PR00446 Hydrogen uptake protein signature 67 77 3.1E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 Pfam PF01750 Hydrogenase maturation protease 30 129 1.5E-12 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 152 7.0E-30 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 Gene3D G3DSA:3.40.50.1450 9 157 1.3E-39 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L12_01875 51657a1e0ed28b661d110412ae819bd3 158 SUPERFAMILY SSF53163 11 156 9.81E-30 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L12_02960 dc410117632f8a0658d513e20e1d08e5 382 Gene3D G3DSA:3.40.50.2000 32 377 1.0E-69 T 23-10-2018 A3L12_02960 dc410117632f8a0658d513e20e1d08e5 382 SUPERFAMILY SSF53756 25 381 2.51E-77 T 23-10-2018 A3L12_02960 dc410117632f8a0658d513e20e1d08e5 382 Gene3D G3DSA:3.40.50.2000 185 361 1.0E-69 T 23-10-2018 A3L12_02960 dc410117632f8a0658d513e20e1d08e5 382 Pfam PF00534 Glycosyl transferases group 1 195 363 2.4E-37 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L12_02960 dc410117632f8a0658d513e20e1d08e5 382 Pfam PF13439 Glycosyltransferase Family 4 27 189 1.2E-12 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L12_04600 661e3876f9ea86dc10cacba70c945807 305 Gene3D G3DSA:1.10.10.10 148 201 3.8E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L12_04600 661e3876f9ea86dc10cacba70c945807 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 157 195 1.5E-7 T 23-10-2018 A3L12_04600 661e3876f9ea86dc10cacba70c945807 305 SUPERFAMILY SSF46785 145 199 2.82E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L12_00410 ee53e33280b05c07ba973d4d2a96313c 347 Pfam PF01594 AI-2E family transporter 9 322 1.7E-37 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L12_06125 eabf45d0234b0acd695348a253607344 128 Pfam PF11469 Ribonuclease III 11 127 2.0E-53 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A3L12_06125 eabf45d0234b0acd695348a253607344 128 Gene3D G3DSA:1.10.1520.20 2 127 7.6E-43 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A3L12_06125 eabf45d0234b0acd695348a253607344 128 SUPERFAMILY SSF69065 7 127 7.67E-46 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A3L12_05820 abb42219d49e947097eaf6951b79aae6 90 Gene3D G3DSA:3.30.310.50 8 90 2.5E-24 T 23-10-2018 A3L12_05820 abb42219d49e947097eaf6951b79aae6 90 Pfam PF09341 Transcription factor Pcc1 18 88 1.3E-11 T 23-10-2018 IPR015419 CTAG/Pcc1 family A3L12_02580 1d706af72b7d748a7b28b5f4b9d6fdcd 399 Gene3D G3DSA:2.20.20.80 109 171 4.5E-46 T 23-10-2018 A3L12_02580 1d706af72b7d748a7b28b5f4b9d6fdcd 399 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 143 369 2.1E-29 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L12_02580 1d706af72b7d748a7b28b5f4b9d6fdcd 399 SUPERFAMILY SSF140914 2 249 1.7E-20 T 23-10-2018 A3L12_02580 1d706af72b7d748a7b28b5f4b9d6fdcd 399 Gene3D G3DSA:1.20.930.50 7 223 4.5E-46 T 23-10-2018 A3L12_02580 1d706af72b7d748a7b28b5f4b9d6fdcd 399 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 28.055 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A3L12_04170 b88740486ac4b61aace3028e76753de4 220 SMART SM00382 25 203 2.3E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04170 b88740486ac4b61aace3028e76753de4 220 Gene3D G3DSA:3.40.50.300 1 218 5.8E-50 T 23-10-2018 A3L12_04170 b88740486ac4b61aace3028e76753de4 220 SUPERFAMILY SSF52540 2 216 3.22E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04170 b88740486ac4b61aace3028e76753de4 220 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_04170 b88740486ac4b61aace3028e76753de4 220 Pfam PF00005 ABC transporter 19 155 3.0E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_06175 78f21c022c6a1bc6318e34da74a828cd 515 SUPERFAMILY SSF49373 312 371 2.43E-5 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L12_06175 78f21c022c6a1bc6318e34da74a828cd 515 Gene3D G3DSA:2.60.40.10 307 382 1.9E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_01505 e23e5889288c4aa5ca4cf7fcbfc1734b 439 Pfam PF13416 Bacterial extracellular solute-binding protein 65 359 3.0E-42 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L12_01505 e23e5889288c4aa5ca4cf7fcbfc1734b 439 Gene3D G3DSA:3.40.190.10 37 433 8.8E-51 T 23-10-2018 A3L12_01505 e23e5889288c4aa5ca4cf7fcbfc1734b 439 SUPERFAMILY SSF53850 40 423 4.35E-58 T 23-10-2018 A3L12_06940 ee0ee23a7fc5525b05ef2cbaccababb0 209 Pfam PF04289 Protein of unknown function (DUF447) 11 181 5.1E-23 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A3L12_06940 ee0ee23a7fc5525b05ef2cbaccababb0 209 SUPERFAMILY SSF50475 3 182 1.12E-28 T 23-10-2018 A3L12_06940 ee0ee23a7fc5525b05ef2cbaccababb0 209 PIRSF PIRSF018747 2 194 5.9E-43 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A3L12_06940 ee0ee23a7fc5525b05ef2cbaccababb0 209 Gene3D G3DSA:2.30.110.10 4 118 2.1E-10 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L12_02520 5e2b6f794e26acde0f645adf5d357995 486 Gene3D G3DSA:1.10.3720.10 270 486 3.5E-22 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02520 5e2b6f794e26acde0f645adf5d357995 486 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 47 2.2E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L12_02520 5e2b6f794e26acde0f645adf5d357995 486 SUPERFAMILY SSF161098 274 467 9.81E-24 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_02520 5e2b6f794e26acde0f645adf5d357995 486 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 298 485 5.8E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 PIRSF PIRSF000460 5 768 4.0E-272 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Gene3D G3DSA:3.40.50.2000 269 406 1.9E-7 T 23-10-2018 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 109 691 1.8E-252 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Pfam PF11897 Protein of unknown function (DUF3417) 15 122 5.2E-31 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Gene3D G3DSA:3.40.50.2000 407 718 2.7E-43 T 23-10-2018 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 SUPERFAMILY SSF53756 15 725 6.67E-205 T 23-10-2018 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 585 597 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Pfam PF00343 Carbohydrate phosphorylase 272 333 1.2E-4 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Pfam PF00343 Carbohydrate phosphorylase 349 611 1.1E-20 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Pfam PF00343 Carbohydrate phosphorylase 126 175 3.2E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L12_01595 7272e9ec27ae601e6dc00453a561a9df 830 Gene3D G3DSA:3.40.50.2000 116 185 3.0E-11 T 23-10-2018 A3L12_03290 5ded3ca8beb775940b7437431b839abf 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 1.7E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_03290 5ded3ca8beb775940b7437431b839abf 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 1.7E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_03290 5ded3ca8beb775940b7437431b839abf 355 Pfam PF00717 Peptidase S24-like 36 92 3.6E-10 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L12_03290 5ded3ca8beb775940b7437431b839abf 355 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 8 113 6.3E-17 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L12_03290 5ded3ca8beb775940b7437431b839abf 355 SUPERFAMILY SSF51306 35 101 1.15E-9 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L12_03955 c31e013f45b3d5b7c50a36c4c381c5a7 633 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 57 175 4.3E-14 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L12_03955 c31e013f45b3d5b7c50a36c4c381c5a7 633 Gene3D G3DSA:3.30.230.10 30 220 1.4E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L12_03955 c31e013f45b3d5b7c50a36c4c381c5a7 633 SUPERFAMILY SSF54211 46 227 1.02E-24 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L12_04545 cedebb06c6c20ea17434a53459851ad9 179 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 4 173 6.6E-13 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L12_05585 cad9fbb353a7aa8c431ed772f30272b3 60 Pfam PF04021 Class III signal peptide 3 27 1.6E-8 T 23-10-2018 IPR007166 Class III signal peptide motif A3L12_07980 c2462cbee93fcee3f3fba09586d96e7f 93 Gene3D G3DSA:3.10.20.30 1 93 3.2E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L12_07980 c2462cbee93fcee3f3fba09586d96e7f 93 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 1 93 1.6E-23 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L12_07980 c2462cbee93fcee3f3fba09586d96e7f 93 Pfam PF02597 ThiS family 3 93 2.2E-16 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L12_07980 c2462cbee93fcee3f3fba09586d96e7f 93 SUPERFAMILY SSF54285 1 93 4.49E-18 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L12_02860 6fbebd836da5f14ee52ea66f14abd421 508 Pfam PF01943 Polysaccharide biosynthesis protein 12 282 1.6E-35 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L12_02860 6fbebd836da5f14ee52ea66f14abd421 508 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 341 476 1.7E-20 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L12_02860 6fbebd836da5f14ee52ea66f14abd421 508 PRINTS PR00173 Glutamate-aspartate symporter signature 126 146 9.3E-6 T 23-10-2018 A3L12_02860 6fbebd836da5f14ee52ea66f14abd421 508 PRINTS PR00173 Glutamate-aspartate symporter signature 278 297 9.3E-6 T 23-10-2018 A3L12_02860 6fbebd836da5f14ee52ea66f14abd421 508 PRINTS PR00173 Glutamate-aspartate symporter signature 469 489 9.3E-6 T 23-10-2018 A3L12_00365 6a6fd346e68bfad90a9f0cf9e67722ab 378 Pfam PF13439 Glycosyltransferase Family 4 14 180 5.8E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L12_00365 6a6fd346e68bfad90a9f0cf9e67722ab 378 Pfam PF00534 Glycosyl transferases group 1 189 352 1.3E-46 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L12_00365 6a6fd346e68bfad90a9f0cf9e67722ab 378 Gene3D G3DSA:3.40.50.2000 179 360 2.3E-92 T 23-10-2018 A3L12_00365 6a6fd346e68bfad90a9f0cf9e67722ab 378 SUPERFAMILY SSF53756 2 376 3.43E-97 T 23-10-2018 A3L12_00365 6a6fd346e68bfad90a9f0cf9e67722ab 378 Gene3D G3DSA:3.40.50.2000 5 361 2.3E-92 T 23-10-2018 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 SMART SM00642 32 377 7.7E-23 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 SUPERFAMILY SSF51011 384 457 8.63E-37 T 23-10-2018 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 Pfam PF00128 Alpha amylase, catalytic domain 55 315 8.7E-12 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 SUPERFAMILY SSF51445 29 381 1.44E-72 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 PRINTS PR00110 Alpha-amylase signature 122 133 3.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 PRINTS PR00110 Alpha-amylase signature 301 313 3.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 PRINTS PR00110 Alpha-amylase signature 214 225 3.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 Gene3D G3DSA:3.20.20.80 24 359 6.2E-108 T 23-10-2018 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 Gene3D G3DSA:2.60.40.1180 360 457 4.7E-50 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 PIRSF PIRSF001021 3 457 4.4E-118 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 A3L12_00010 467711f75ed989c00b8f7f5c467300a2 457 Pfam PF09154 Domain of unknown function (DUF1939) 386 452 1.5E-20 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 A3L12_06715 25e5da804671a08957731a602e55fee7 149 SMART SM00465 18 113 9.6E-6 T 23-10-2018 IPR000305 GIY-YIG endonuclease A3L12_06715 25e5da804671a08957731a602e55fee7 149 Pfam PF01986 Domain of unknown function DUF123 25 110 3.1E-20 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A3L12_04335 b2a808b5cf390baf9a2b1410dd811326 100 Pfam PF11491 Protein of unknown function (DUF3213) 13 94 4.0E-35 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A3L12_04335 b2a808b5cf390baf9a2b1410dd811326 100 Gene3D G3DSA:3.30.70.1750 4 98 3.5E-31 T 23-10-2018 A3L12_05500 b19e4a511d7aac56697b80b9b9716096 266 Pfam PF10869 Protein of unknown function (DUF2666) 5 114 1.8E-10 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L12_05500 b19e4a511d7aac56697b80b9b9716096 266 Pfam PF10869 Protein of unknown function (DUF2666) 138 265 1.9E-36 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L12_05500 b19e4a511d7aac56697b80b9b9716096 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 265 1.0E-40 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L12_05500 b19e4a511d7aac56697b80b9b9716096 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 5 102 2.0E-26 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L12_00115 6df60544ace057ca1fe4bda19e67ac86 298 Pfam PF00482 Type II secretion system (T2SS), protein F 101 225 1.0E-17 T 23-10-2018 IPR018076 Type II secretion system F domain A3L12_00115 6df60544ace057ca1fe4bda19e67ac86 298 Gene3D G3DSA:1.20.81.30 91 205 4.4E-8 T 23-10-2018 A3L12_03195 081a5691ee4726292dbf1e8b0989d0fa 802 Pfam PF10102 Domain of unknown function (DUF2341) 385 453 1.5E-17 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L12_00390 749c2f140d0c49c077c88c9246ee8905 391 Gene3D G3DSA:1.20.1250.20 214 391 1.5E-18 T 23-10-2018 A3L12_00390 749c2f140d0c49c077c88c9246ee8905 391 Gene3D G3DSA:1.20.1250.20 11 206 7.8E-25 T 23-10-2018 A3L12_00390 749c2f140d0c49c077c88c9246ee8905 391 SUPERFAMILY SSF103473 1 389 1.02E-55 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_00390 749c2f140d0c49c077c88c9246ee8905 391 Pfam PF07690 Major Facilitator Superfamily 18 258 2.6E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_05270 de38f6f72248a69cb53adc789929bfec 411 Gene3D G3DSA:3.40.50.2300 139 325 8.7E-82 T 23-10-2018 A3L12_05270 de38f6f72248a69cb53adc789929bfec 411 Gene3D G3DSA:3.40.50.2300 37 313 8.7E-82 T 23-10-2018 A3L12_05270 de38f6f72248a69cb53adc789929bfec 411 SUPERFAMILY SSF53822 47 296 6.59E-9 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L12_05270 de38f6f72248a69cb53adc789929bfec 411 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 342 1.5E-51 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A3L12_05160 96d635c3a7c8342c6e406c7c23fa9ec6 293 Pfam PF03547 Membrane transport protein 148 283 3.4E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L12_05160 96d635c3a7c8342c6e406c7c23fa9ec6 293 Pfam PF03547 Membrane transport protein 2 125 1.9E-8 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L12_00825 f7a88661165c2cf247ee509102ae7dec 52 SMART SM01377 1 46 5.2E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L12_00825 f7a88661165c2cf247ee509102ae7dec 52 Gene3D G3DSA:2.20.28.70 1 49 1.1E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L12_00825 f7a88661165c2cf247ee509102ae7dec 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.547 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L12_00825 f7a88661165c2cf247ee509102ae7dec 52 SUPERFAMILY SSF57829 2 46 1.28E-15 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 12 132 1.6E-44 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 Pfam PF01597 Glycine cleavage H-protein 13 133 8.1E-49 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 Gene3D G3DSA:2.40.50.100 2 132 4.9E-50 T 23-10-2018 A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.371 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L12_02165 bfc844a902f7df93abc335d8cc0b27ae 134 SUPERFAMILY SSF51230 9 133 6.02E-41 T 23-10-2018 IPR011053 Single hybrid motif A3L12_05575 2f0399856ea8010391b290c2086a57aa 412 Pfam PF02163 Peptidase family M50 298 344 2.2E-8 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L12_07875 3927a8fc22e71913e799a4d43b660267 267 Gene3D G3DSA:3.10.270.10 3 266 2.7E-66 T 23-10-2018 A3L12_07875 3927a8fc22e71913e799a4d43b660267 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 4 263 5.5E-65 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A3L12_05505 5bb9ca076bb2641581c00d81f94ce3a8 123 SUPERFAMILY SSF102712 3 120 5.36E-26 T 23-10-2018 A3L12_05505 5bb9ca076bb2641581c00d81f94ce3a8 123 Gene3D G3DSA:3.40.140.10 2 123 3.0E-25 T 23-10-2018 A3L12_05505 5bb9ca076bb2641581c00d81f94ce3a8 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 12 100 6.9E-11 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L12_03510 cff99f3bede0c9b016e65f5710dd54af 427 Gene3D G3DSA:1.20.1250.20 31 418 4.7E-40 T 23-10-2018 A3L12_03510 cff99f3bede0c9b016e65f5710dd54af 427 SUPERFAMILY SSF103473 38 417 4.19E-44 T 23-10-2018 IPR036259 MFS transporter superfamily A3L12_03510 cff99f3bede0c9b016e65f5710dd54af 427 Pfam PF07690 Major Facilitator Superfamily 41 386 8.5E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L12_03700 6c9b1c1e7c4c5f1110438f5f4e704801 194 Gene3D G3DSA:3.40.920.10 1 194 1.9E-33 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_03700 6c9b1c1e7c4c5f1110438f5f4e704801 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 2.8E-32 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L12_03700 6c9b1c1e7c4c5f1110438f5f4e704801 194 SUPERFAMILY SSF53323 3 192 6.28E-25 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_05850 e573f96436e2453243c1488dd6af00d7 241 SUPERFAMILY SSF50249 134 206 3.43E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_05850 e573f96436e2453243c1488dd6af00d7 241 Gene3D G3DSA:2.40.50.140 125 241 5.3E-33 T 23-10-2018 A3L12_05850 e573f96436e2453243c1488dd6af00d7 241 Pfam PF01588 Putative tRNA binding domain 139 223 8.3E-17 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L12_05850 e573f96436e2453243c1488dd6af00d7 241 Gene3D G3DSA:1.20.1440.150 1 124 1.6E-57 T 23-10-2018 A3L12_05605 b73f99dcbb56daaa6fc9a74ac8bef133 79 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 78 1.5E-8 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A3L12_05765 e5a052e332a84f4f62782f763e78fbbb 85 Gene3D G3DSA:1.20.1280.290 1 85 3.7E-11 T 23-10-2018 A3L12_05765 e5a052e332a84f4f62782f763e78fbbb 85 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 7 76 7.2E-7 T 23-10-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 A3L12_01600 91356895710bef9a6bb37097e7ba0959 235 SUPERFAMILY SSF53738 128 206 7.06E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_01600 91356895710bef9a6bb37097e7ba0959 235 Gene3D G3DSA:3.40.120.10 3 73 9.4E-6 T 23-10-2018 A3L12_01600 91356895710bef9a6bb37097e7ba0959 235 SUPERFAMILY SSF53738 8 71 1.33E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L12_05375 80db283078b700f95548158b2fbbadb8 256 Pfam PF01925 Sulfite exporter TauE/SafE 10 246 4.7E-58 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L12_01465 64741a9d7e262e7eab59fe69d50c05b2 429 SUPERFAMILY SSF48452 159 355 6.49E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_01465 64741a9d7e262e7eab59fe69d50c05b2 429 Gene3D G3DSA:1.25.40.10 292 410 2.7E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_04900 0de6c200070a5aa8c85134ad36ef16b0 137 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 7 133 6.7E-50 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A3L12_04900 0de6c200070a5aa8c85134ad36ef16b0 137 SUPERFAMILY SSF101307 2 133 1.83E-32 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A3L12_04900 0de6c200070a5aa8c85134ad36ef16b0 137 Gene3D G3DSA:1.10.3760.10 1 136 1.1E-9 T 23-10-2018 A3L12_04900 0de6c200070a5aa8c85134ad36ef16b0 137 Pfam PF04608 Phosphatidylglycerophosphatase A 56 132 6.9E-7 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A3L12_06095 4028ecf2c7fe657be3afc890c61f93e8 289 Pfam PF12679 ABC-2 family transporter protein 6 288 2.1E-41 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L12_04960 eb4644d508975af5f77c26c602a5bfbd 616 Gene3D G3DSA:3.20.70.20 36 596 3.4E-68 T 23-10-2018 A3L12_04960 eb4644d508975af5f77c26c602a5bfbd 616 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 25 613 9.3E-152 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A3L12_04960 eb4644d508975af5f77c26c602a5bfbd 616 SUPERFAMILY SSF51998 26 598 2.93E-124 T 23-10-2018 A3L12_04960 eb4644d508975af5f77c26c602a5bfbd 616 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 25 614 3.4E-147 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A3L12_00305 108a8e8cf94509b729e0afcc290b49b6 333 SUPERFAMILY SSF52540 4 239 1.82E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_00305 108a8e8cf94509b729e0afcc290b49b6 333 Pfam PF00005 ABC transporter 20 159 1.1E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L12_00305 108a8e8cf94509b729e0afcc290b49b6 333 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L12_00305 108a8e8cf94509b729e0afcc290b49b6 333 Gene3D G3DSA:3.40.50.300 3 235 1.5E-74 T 23-10-2018 A3L12_00305 108a8e8cf94509b729e0afcc290b49b6 333 SMART SM00382 26 209 3.0E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_00370 b31ece9954088b4ddcd8255cef1b1d3d 310 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 290 6.1E-19 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L12_01390 ea08bdc42bfac4dd8a876937485834b9 89 Pfam PF04324 BFD-like [2Fe-2S] binding domain 5 57 2.9E-15 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L12_01390 ea08bdc42bfac4dd8a876937485834b9 89 Gene3D G3DSA:1.10.10.1100 1 66 2.2E-23 T 23-10-2018 A3L12_01520 86b7a2543e0765a5ed328eeb2c3cf29a 380 SUPERFAMILY SSF53448 3 373 3.75E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_01520 86b7a2543e0765a5ed328eeb2c3cf29a 380 Pfam PF00535 Glycosyl transferase family 2 5 135 3.5E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_01520 86b7a2543e0765a5ed328eeb2c3cf29a 380 Gene3D G3DSA:3.90.550.10 1 268 2.0E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_03325 d07c426f0fee4950811ea1639dbfdb92 352 Pfam PF04138 GtrA-like protein 236 351 1.6E-25 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A3L12_03325 d07c426f0fee4950811ea1639dbfdb92 352 Pfam PF00535 Glycosyl transferase family 2 4 169 1.0E-37 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L12_03325 d07c426f0fee4950811ea1639dbfdb92 352 Gene3D G3DSA:3.90.550.10 1 239 1.1E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_03325 d07c426f0fee4950811ea1639dbfdb92 352 SUPERFAMILY SSF53448 2 236 5.04E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_05325 6b36b4737e7fdc3f357b72ec74e66a33 171 SUPERFAMILY SSF53323 2 167 9.42E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_05325 6b36b4737e7fdc3f357b72ec74e66a33 171 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 6.0E-36 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L12_05325 6b36b4737e7fdc3f357b72ec74e66a33 171 Gene3D G3DSA:3.40.920.10 1 169 4.6E-52 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_04105 b6e9a41b6419ea6d1cf029dd0bd650f7 274 Pfam PF00892 EamA-like transporter family 6 130 4.4E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_04105 b6e9a41b6419ea6d1cf029dd0bd650f7 274 Pfam PF00892 EamA-like transporter family 145 271 1.2E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L12_04105 b6e9a41b6419ea6d1cf029dd0bd650f7 274 SUPERFAMILY SSF103481 180 271 2.88E-8 T 23-10-2018 A3L12_04105 b6e9a41b6419ea6d1cf029dd0bd650f7 274 SUPERFAMILY SSF103481 38 134 2.48E-12 T 23-10-2018 A3L12_02105 43575186f7198662542f00254729bb59 146 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 72 9.2E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_02105 43575186f7198662542f00254729bb59 146 Gene3D G3DSA:3.40.50.620 2 144 3.1E-39 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_02105 43575186f7198662542f00254729bb59 146 SUPERFAMILY SSF52374 5 140 1.21E-27 T 23-10-2018 A3L12_02105 43575186f7198662542f00254729bb59 146 Hamap MF_02115 FAD synthase [ribL]. 5 145 29.682 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L12_02105 43575186f7198662542f00254729bb59 146 Pfam PF01467 Cytidylyltransferase-like 8 138 1.2E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L12_02315 a020a2e440ac85d5890ec69c5796eb4b 308 Gene3D G3DSA:1.10.4200.10 25 293 1.7E-58 T 23-10-2018 A3L12_02315 a020a2e440ac85d5890ec69c5796eb4b 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 286 4.6E-47 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A3L12_04060 4d8f3e04906c1cab558e431fac7931f3 244 PIRSF PIRSF019322 2 244 4.2E-87 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L12_04060 4d8f3e04906c1cab558e431fac7931f3 244 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 236 5.3E-71 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L12_03890 6e3957b8ab00a156a99a52e628010f4d 192 Gene3D G3DSA:3.40.50.300 2 189 2.4E-40 T 23-10-2018 A3L12_03890 6e3957b8ab00a156a99a52e628010f4d 192 Pfam PF13238 AAA domain 3 138 3.2E-18 T 23-10-2018 A3L12_03890 6e3957b8ab00a156a99a52e628010f4d 192 SUPERFAMILY SSF52540 1 188 8.74E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_04875 e0b0e162c27a3520c4b91ea93723c87e 178 Pfam PF12804 MobA-like NTP transferase domain 3 110 6.7E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L12_04875 e0b0e162c27a3520c4b91ea93723c87e 178 SUPERFAMILY SSF53448 1 173 6.98E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_04875 e0b0e162c27a3520c4b91ea93723c87e 178 Gene3D G3DSA:3.90.550.10 2 175 1.7E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L12_03460 531796b929644ca9eb2e867983657593 184 SUPERFAMILY SSF52540 2 181 6.65E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_03460 531796b929644ca9eb2e867983657593 184 Gene3D G3DSA:3.40.50.300 1 184 9.8E-51 T 23-10-2018 A3L12_03460 531796b929644ca9eb2e867983657593 184 Pfam PF01926 50S ribosome-binding GTPase 2 129 5.3E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L12_05255 d797c026d795e8641c7308d9d66543a4 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 274 3.9E-33 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L12_03490 638fb5eb376914e1ee36a45d779cde1d 124 SUPERFAMILY SSF50249 24 76 7.28E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_07500 9bc9bc9d9041b70de7723019708ff7df 375 Pfam PF01497 Periplasmic binding protein 54 296 7.8E-31 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L12_07500 9bc9bc9d9041b70de7723019708ff7df 375 SUPERFAMILY SSF53807 31 323 3.77E-57 T 23-10-2018 A3L12_07500 9bc9bc9d9041b70de7723019708ff7df 375 Gene3D G3DSA:3.40.50.1980 175 371 2.0E-83 T 23-10-2018 A3L12_07500 9bc9bc9d9041b70de7723019708ff7df 375 Gene3D G3DSA:3.40.50.1980 28 174 5.4E-54 T 23-10-2018 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 SUPERFAMILY SSF161070 4 485 1.09E-98 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 2.1E-19 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 Pfam PF00209 Sodium:neurotransmitter symporter family 157 492 9.2E-23 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 411 431 1.1E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.1E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 337 356 1.1E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_01030 8484870e79bb7e2491b469cb67c3362e 518 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.1E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L12_05335 13b0e7e1be89aec9100381c18ca60bfc 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 4.0E-37 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L12_05335 13b0e7e1be89aec9100381c18ca60bfc 281 SUPERFAMILY SSF52518 19 260 9.65E-77 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L12_05335 13b0e7e1be89aec9100381c18ca60bfc 281 Gene3D G3DSA:3.40.50.970 87 257 2.5E-31 T 23-10-2018 A3L12_01640 e3e8aae35da29220b240e5cabd1baa5a 235 PIRSF PIRSF016933 4 224 2.6E-33 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A3L12_01640 e3e8aae35da29220b240e5cabd1baa5a 235 Pfam PF13367 Protease prsW family 31 202 1.5E-29 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L12_01135 806dc0d4dc654e7d95d25a21f1bc9360 386 Pfam PF04981 NMD3 family 6 276 1.2E-63 T 23-10-2018 IPR007064 Nmd3, N-terminal A3L12_01135 806dc0d4dc654e7d95d25a21f1bc9360 386 SUPERFAMILY SSF50249 335 382 3.68E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L12_01135 806dc0d4dc654e7d95d25a21f1bc9360 386 Gene3D G3DSA:2.40.50.140 332 386 1.2E-8 T 23-10-2018 A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 SUPERFAMILY SSF54631 39 181 3.31E-29 T 23-10-2018 A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 SMART SM00116 56 103 0.051 T 23-10-2018 IPR000644 CBS domain A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 SMART SM00116 134 182 1.8E-8 T 23-10-2018 IPR000644 CBS domain A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 Gene3D G3DSA:3.10.580.10 109 184 3.0E-15 T 23-10-2018 A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 Pfam PF00571 CBS domain 127 181 2.9E-12 T 23-10-2018 IPR000644 CBS domain A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 Pfam PF00571 CBS domain 52 101 1.2E-11 T 23-10-2018 IPR000644 CBS domain A3L12_00250 6f0368bc947a24a2e15767d00589f014 186 Gene3D G3DSA:3.10.580.10 13 103 1.4E-12 T 23-10-2018 A3L12_05815 2636ed740fec578842a0a41e96a4f46d 211 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 27.883 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A3L12_05815 2636ed740fec578842a0a41e96a4f46d 211 SUPERFAMILY SSF52954 1 193 6.15E-33 T 23-10-2018 A3L12_05815 2636ed740fec578842a0a41e96a4f46d 211 SMART SM00879 3 190 1.7E-15 T 23-10-2018 IPR007109 Brix domain A3L12_05815 2636ed740fec578842a0a41e96a4f46d 211 Gene3D G3DSA:3.40.50.10480 1 187 1.7E-32 T 23-10-2018 A3L12_00260 9418a7b340cd6c9a3cfa293551352f5d 376 Gene3D G3DSA:1.20.1530.20 1 375 1.3E-86 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L12_00260 9418a7b340cd6c9a3cfa293551352f5d 376 Pfam PF00999 Sodium/hydrogen exchanger family 9 371 6.7E-69 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L12_07670 b4b41d4933cde6372847285498ec7d73 153 Pfam PF06695 Putative small multi-drug export protein 17 143 9.4E-29 T 23-10-2018 IPR009577 Putative small multi-drug export A3L12_06805 067ae585fc3c351a590e2bad25f97395 252 Pfam PF05763 Protein of unknown function (DUF835) 133 247 7.2E-32 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L12_07550 296ee684c69cf46745ed8e119e7c0280 156 Pfam PF01917 Archaebacterial flagellin 5 153 3.7E-21 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L12_02880 667c555087a59560daed6141afeb316a 311 SUPERFAMILY SSF64182 4 311 2.35E-23 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L12_07580 95e6c639248862ec11d91eaefb829cb5 213 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 1.7E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L12_07580 95e6c639248862ec11d91eaefb829cb5 213 Pfam PF01917 Archaebacterial flagellin 8 199 2.9E-49 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L12_04890 cb9ed16cddf8303cbd69ec31152fa1a0 149 SUPERFAMILY SSF52402 2 149 1.6E-32 T 23-10-2018 A3L12_04890 cb9ed16cddf8303cbd69ec31152fa1a0 149 Gene3D G3DSA:3.40.50.620 1 149 6.0E-42 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L12_04890 cb9ed16cddf8303cbd69ec31152fa1a0 149 PRINTS PR01438 Universal stress protein signature 127 149 1.9E-14 T 23-10-2018 IPR006015 Universal stress protein A A3L12_04890 cb9ed16cddf8303cbd69ec31152fa1a0 149 PRINTS PR01438 Universal stress protein signature 2 20 1.9E-14 T 23-10-2018 IPR006015 Universal stress protein A A3L12_04890 cb9ed16cddf8303cbd69ec31152fa1a0 149 Pfam PF00582 Universal stress protein family 1 149 1.5E-30 T 23-10-2018 IPR006016 UspA A3L12_02155 f4615ce7191ea29353d896b4e41f3fe2 260 PIRSF PIRSF004853 1 252 5.6E-115 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L12_02155 f4615ce7191ea29353d896b4e41f3fe2 260 Gene3D G3DSA:3.40.50.12640 1 260 7.7E-118 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A3L12_02155 f4615ce7191ea29353d896b4e41f3fe2 260 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 251 7.0E-88 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L12_02155 f4615ce7191ea29353d896b4e41f3fe2 260 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 67 240 3.1E-77 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L12_02700 cd65932c269285fa4e42c20c36a64d48 174 SUPERFAMILY SSF54862 6 139 6.03E-37 T 23-10-2018 A3L12_02700 cd65932c269285fa4e42c20c36a64d48 174 Gene3D G3DSA:3.30.70.20 30 142 1.3E-20 T 23-10-2018 A3L12_02700 cd65932c269285fa4e42c20c36a64d48 174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L12_02700 cd65932c269285fa4e42c20c36a64d48 174 Pfam PF12800 4Fe-4S binding domain 14 28 0.098 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_02700 cd65932c269285fa4e42c20c36a64d48 174 Pfam PF13247 4Fe-4S dicluster domain 53 131 8.0E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L12_01110 a4d8e46bae89bc73c685f158debd4021 373 Pfam PF01901 Putative O-antigen polymerase 103 321 8.1E-14 T 23-10-2018 IPR002760 Putative O-antigen polymerase A3L12_05660 6f30fcd34af3c64fd7f853a054b806c9 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 8.3E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L12_06380 a7a6ef529c34f0367b88e881b5fa9a8d 472 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 111 412 4.1E-77 T 23-10-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC A3L12_06380 a7a6ef529c34f0367b88e881b5fa9a8d 472 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 113 173 7.9E-11 T 23-10-2018 IPR019121 CRISPR-associated protein, CXXC-CXXC domain A3L12_07290 8f1ea57c6569be45819605fc2bef69c1 120 Pfam PF09685 Domain of unknown function (DUF4870) 24 106 2.1E-9 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A3L12_05480 665108af62810a3f20c4f67624bc51b1 261 SUPERFAMILY SSF56770 1 212 1.44E-44 T 23-10-2018 A3L12_05480 665108af62810a3f20c4f67624bc51b1 261 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 148 6.6E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L12_05480 665108af62810a3f20c4f67624bc51b1 261 Gene3D G3DSA:3.40.50.700 2 160 1.2E-40 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L12_03220 506377e9cf4698ee4ca9d2821b7055da 210 Pfam PF04021 Class III signal peptide 5 30 1.5E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L12_05595 da4a5268d225ba535df4b59b49e6ded6 753 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 203 2.9E-18 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L12_07605 4f55964f828ae5a039ff878fec74875b 368 SUPERFAMILY SSF101960 11 346 2.35E-41 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L12_07605 4f55964f828ae5a039ff878fec74875b 368 Pfam PF01458 Uncharacterized protein family (UPF0051) 133 340 9.2E-29 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L12_07565 b7b162ea74a5a0b97a8fa539b8cdf41e 158 Gene3D G3DSA:1.20.5.170 35 140 7.3E-6 T 23-10-2018 A3L12_07565 b7b162ea74a5a0b97a8fa539b8cdf41e 158 SUPERFAMILY SSF58104 40 124 3.66E-5 T 23-10-2018 A3L12_07565 b7b162ea74a5a0b97a8fa539b8cdf41e 158 Pfam PF05377 Flagella accessory protein C (FlaC) 48 101 3.8E-20 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A3L12_00985 472cade63df0dabe6b6d8080b450b9ad 243 SUPERFAMILY SSF89550 21 225 6.67E-33 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L12_00985 472cade63df0dabe6b6d8080b450b9ad 243 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 19 230 22.923 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A3L12_00985 472cade63df0dabe6b6d8080b450b9ad 243 Pfam PF01876 RNase P subunit p30 29 218 2.5E-32 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L12_00985 472cade63df0dabe6b6d8080b450b9ad 243 Gene3D G3DSA:3.20.20.140 9 228 4.1E-97 T 23-10-2018 A3L12_00985 472cade63df0dabe6b6d8080b450b9ad 243 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 125 217 3.0E-39 T 23-10-2018 A3L12_00060 f13b0c3e35dd5e06992b0b7de5f12046 277 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 12 272 1.9E-66 T 23-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A3L12_00060 f13b0c3e35dd5e06992b0b7de5f12046 277 Gene3D G3DSA:1.10.3720.10 59 273 2.0E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00060 f13b0c3e35dd5e06992b0b7de5f12046 277 SUPERFAMILY SSF161098 21 266 4.71E-36 T 23-10-2018 IPR035906 MetI-like superfamily A3L12_00060 f13b0c3e35dd5e06992b0b7de5f12046 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 270 1.5E-18 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L12_03370 67e7777c940bc91e726883e5cb447261 109 Pfam PF01906 Putative heavy-metal-binding 3 105 1.9E-35 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L12_03370 67e7777c940bc91e726883e5cb447261 109 SUPERFAMILY SSF117782 4 108 3.92E-35 T 23-10-2018 IPR035439 UPF0145 domain superfamily A3L12_03370 67e7777c940bc91e726883e5cb447261 109 Gene3D G3DSA:3.30.110.70 3 109 9.6E-32 T 23-10-2018 A3L12_03370 67e7777c940bc91e726883e5cb447261 109 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 3 105 24.638 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L12_05070 836e2c114fc2741cb760bc465a2e3eb6 364 SUPERFAMILY SSF47240 6 141 3.58E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_05070 836e2c114fc2741cb760bc465a2e3eb6 364 Pfam PF02915 Rubrerythrin 14 139 1.9E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_05070 836e2c114fc2741cb760bc465a2e3eb6 364 Pfam PF01988 VIT family 149 353 1.1E-43 T 23-10-2018 IPR008217 Ccc1 family A3L12_05070 836e2c114fc2741cb760bc465a2e3eb6 364 Gene3D G3DSA:1.20.1260.10 6 144 3.6E-6 T 23-10-2018 IPR012347 Ferritin-like A3L12_04200 3a02f70d49de41dc5cb13a9f9ab6bfae 455 Pfam PF09852 Predicted membrane protein (DUF2079) 9 382 2.5E-50 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 A3L12_03070 608694b74c42f8445d40836d62a369cd 198 Pfam PF07826 IMP cyclohydrolase-like protein 3 186 3.6E-46 T 23-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_03070 608694b74c42f8445d40836d62a369cd 198 SUPERFAMILY SSF75569 2 195 2.75E-57 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_03070 608694b74c42f8445d40836d62a369cd 198 Hamap MF_00705 IMP cyclohydrolase [purO]. 1 198 62.796 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_03070 608694b74c42f8445d40836d62a369cd 198 Gene3D G3DSA:3.60.20.20 2 197 7.7E-49 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_03070 608694b74c42f8445d40836d62a369cd 198 TIGRFAM TIGR01922 purO_arch: IMP cyclohydrolase 3 193 2.6E-48 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L12_05555 0e860733fcc9bbb7aa6c584764f3714d 157 Gene3D G3DSA:2.60.40.1260 54 150 4.7E-12 T 23-10-2018 IPR036415 Lamin tail domain superfamily A3L12_05555 0e860733fcc9bbb7aa6c584764f3714d 157 SUPERFAMILY SSF74853 42 146 4.32E-24 T 23-10-2018 IPR036415 Lamin tail domain superfamily A3L12_05555 0e860733fcc9bbb7aa6c584764f3714d 157 Pfam PF00932 Lamin Tail Domain 39 147 2.1E-29 T 23-10-2018 IPR001322 Lamin tail domain A3L12_06135 317196bf52a8b8c0e8e987bda4bc8d83 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 196 8.7E-49 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A3L12_01280 8652d265f923ca73dcd6850a4aa6c1af 338 Gene3D G3DSA:1.20.1080.10 12 273 1.1E-77 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A3L12_01280 8652d265f923ca73dcd6850a4aa6c1af 338 Pfam PF01226 Formate/nitrite transporter 16 263 1.3E-72 T 23-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 A3L12_01205 09f75c517b7efa7f6a1b379e3675985f 115 Gene3D G3DSA:3.30.56.30 1 106 9.2E-29 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_01205 09f75c517b7efa7f6a1b379e3675985f 115 Pfam PF01922 SRP19 protein 5 80 5.1E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_01205 09f75c517b7efa7f6a1b379e3675985f 115 SUPERFAMILY SSF69695 1 106 5.4E-22 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 Gene3D G3DSA:3.30.780.10 20 98 2.9E-28 T 23-10-2018 A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.009 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 Pfam PF01253 Translation initiation factor SUI1 19 89 2.2E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 PIRSF PIRSF037511 5 97 2.2E-25 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 96 3.2E-35 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L12_00630 1b68c1ba43cfe47850fda359b5588bed 98 SUPERFAMILY SSF55159 5 92 4.19E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A3L12_05790 51c0e4119c69f335089ef1a6dd3bae75 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 36.515 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L12_05790 51c0e4119c69f335089ef1a6dd3bae75 253 Pfam PF04055 Radical SAM superfamily 31 202 4.1E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L12_05790 51c0e4119c69f335089ef1a6dd3bae75 253 SUPERFAMILY SSF102114 32 222 5.89E-13 T 23-10-2018 A3L12_05790 51c0e4119c69f335089ef1a6dd3bae75 253 Pfam PF13394 4Fe-4S single cluster domain 29 103 3.7E-6 T 23-10-2018 A3L12_05790 51c0e4119c69f335089ef1a6dd3bae75 253 Gene3D G3DSA:3.20.20.70 4 253 4.8E-25 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L12_01830 2505120653eb9895cd65750d0a7d3f50 189 Gene3D G3DSA:2.60.120.10 1 189 4.4E-74 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L12_01830 2505120653eb9895cd65750d0a7d3f50 189 PIRSF PIRSF019325 1 189 5.8E-74 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L12_01830 2505120653eb9895cd65750d0a7d3f50 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 182 1.5E-39 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L12_01830 2505120653eb9895cd65750d0a7d3f50 189 SUPERFAMILY SSF51182 1 187 1.02E-41 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L12_03430 3c56b8e5b75df66030b2e874e7a447c9 255 SUPERFAMILY SSF109604 50 169 2.66E-9 T 23-10-2018 A3L12_03430 3c56b8e5b75df66030b2e874e7a447c9 255 Pfam PF01966 HD domain 86 170 4.6E-5 T 23-10-2018 IPR006674 HD domain A3L12_03430 3c56b8e5b75df66030b2e874e7a447c9 255 Gene3D G3DSA:1.10.3210.10 27 206 6.1E-8 T 23-10-2018 A3L12_03430 3c56b8e5b75df66030b2e874e7a447c9 255 SMART SM00471 48 180 0.001 T 23-10-2018 IPR003607 HD/PDEase domain A3L12_00095 2b6baf03477260a9da5b50cc0a04f800 481 Pfam PF04415 Protein of unknown function (DUF515) 34 480 1.1E-137 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A3L12_04080 450e275526c1e4e289a980359dd0ca36 198 PIRSF PIRSF004897 1 165 6.9E-44 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L12_03635 c0bc6d6ebdc7e476abf6fa41adbc9fff 259 Pfam PF01435 Peptidase family M48 54 245 2.6E-21 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L12_03635 c0bc6d6ebdc7e476abf6fa41adbc9fff 259 Gene3D G3DSA:3.30.2010.10 48 132 9.6E-18 T 23-10-2018 A3L12_04465 149465b0237e4e39b46098f17acab979 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 1.0E-21 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L12_04810 f2ab7cf78b643ea3e8d159068c7271a9 732 Gene3D G3DSA:2.60.40.10 622 709 7.4E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L12_04540 5229e10e8510a23f57f0f220aa865cf8 400 Pfam PF13401 AAA domain 65 210 2.5E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L12_04540 5229e10e8510a23f57f0f220aa865cf8 400 SUPERFAMILY SSF52540 55 303 1.03E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L12_05655 de6fd12eaea29d8a4ff71b8f6e1c7f64 168 PIRSF PIRSF019239 4 168 3.8E-56 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_05655 de6fd12eaea29d8a4ff71b8f6e1c7f64 168 Pfam PF01899 Na+/H+ ion antiporter subunit 15 164 5.1E-49 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L12_06400 34120aa16a96a7c95de1635d2ed51bc8 170 Pfam PF01930 Domain of unknown function DUF83 14 169 6.1E-53 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 A3L12_06400 34120aa16a96a7c95de1635d2ed51bc8 170 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 169 4.8E-23 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L12_06400 34120aa16a96a7c95de1635d2ed51bc8 170 Gene3D G3DSA:3.90.320.10 5 170 2.6E-8 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L12_04285 bee1c7b6813fda8029416404e736c06e 97 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 93 2.2E-18 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L12_00145 b43310cb399a93f4fc4226eb1f2f0bb6 407 Pfam PF01882 Protein of unknown function DUF58 188 267 5.4E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L12_02065 097dc4fa6caa400e2c86e834e2512168 281 Gene3D G3DSA:3.40.1190.20 1 275 2.7E-90 T 23-10-2018 IPR029056 Ribokinase-like A3L12_02065 097dc4fa6caa400e2c86e834e2512168 281 SUPERFAMILY SSF53613 1 265 5.8E-34 T 23-10-2018 IPR029056 Ribokinase-like A3L12_02065 097dc4fa6caa400e2c86e834e2512168 281 Pfam PF00294 pfkB family carbohydrate kinase 153 260 1.2E-5 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L12_02900 310055b941bc201dc4498c7717281b07 75 SUPERFAMILY SSF47598 7 49 5.89E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L12_07385 081a65f8d0be28b824e7bbccebeea09a 159 Pfam PF02915 Rubrerythrin 5 138 8.2E-16 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L12_07385 081a65f8d0be28b824e7bbccebeea09a 159 SUPERFAMILY SSF47240 1 147 3.72E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L12_07385 081a65f8d0be28b824e7bbccebeea09a 159 Gene3D G3DSA:1.20.1260.10 1 143 3.8E-25 T 23-10-2018 IPR012347 Ferritin-like A3L12_04485 cff7c5f76eeffeeca77692b9d86d4443 150 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 10 136 3.1E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L12_04420 d936ad2f536ba302eebb68916d882de1 215 SUPERFAMILY SSF56112 14 154 2.74E-15 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L12_06510 c8665bb5dbab227afae124f4e6563157 270 Pfam PF12679 ABC-2 family transporter protein 13 209 2.5E-17 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L12_02310 e978734ad6e7c23abb3c8209e47a319f 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 3.0E-24 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L12_02310 e978734ad6e7c23abb3c8209e47a319f 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 92 3.0E-36 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L12_02310 e978734ad6e7c23abb3c8209e47a319f 93 Gene3D G3DSA:3.30.2320.10 1 93 4.7E-25 T 23-10-2018 A3L12_02310 e978734ad6e7c23abb3c8209e47a319f 93 SUPERFAMILY SSF111057 2 92 2.22E-29 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L12_01685 ddc4f70d9d51e096293ec553e58f47c5 404 Pfam PF12698 ABC-2 family transporter protein 24 393 4.3E-33 T 23-10-2018 A3L12_03260 1473c46263507932d452abf6e91c65d0 177 PIRSF PIRSF006533 1 175 1.2E-53 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L12_03260 1473c46263507932d452abf6e91c65d0 177 Pfam PF04019 Protein of unknown function (DUF359) 50 171 1.7E-38 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L12_03260 1473c46263507932d452abf6e91c65d0 177 Hamap MF_00590 UPF0218 protein . 6 173 29.118 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L12_02790 21b1355af02b5fa23e3892935c099221 327 Pfam PF07760 Protein of unknown function (DUF1616) 11 324 3.6E-97 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A3L12_02790 21b1355af02b5fa23e3892935c099221 327 PIRSF PIRSF018671 2 327 4.8E-119 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A3L12_01845 b7ae73ff2b816e79907f1e7a514d9392 59 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 3 59 1.0E-24 T 23-10-2018 IPR020199 Uncharacterised protein family PYRAB06030 A3L12_02215 16160a453478622d7a3b8ece71126870 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 4.0E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L12_02215 16160a453478622d7a3b8ece71126870 202 SUPERFAMILY SSF53323 4 199 1.26E-43 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_02215 16160a453478622d7a3b8ece71126870 202 Gene3D G3DSA:3.40.920.10 1 201 3.2E-46 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L12_02215 16160a453478622d7a3b8ece71126870 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 2.7E-84 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L12_00020 0c412563ed380fbca26becfc36247ce6 101 Gene3D G3DSA:3.30.70.1340 1 86 8.4E-35 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L12_00020 0c412563ed380fbca26becfc36247ce6 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 91 1.5E-38 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L12_00020 0c412563ed380fbca26becfc36247ce6 101 SUPERFAMILY SSF160363 4 93 2.35E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L12_00020 0c412563ed380fbca26becfc36247ce6 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 2.0E-35 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L12_03190 93f300620965be486f3f13ee9a3d3501 248 Pfam PF09874 Predicted membrane protein (DUF2101) 22 228 1.2E-79 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A3L12_04395 d0ebe0505aa7835fb9a6af25c204c084 358 Gene3D G3DSA:1.25.40.10 1 357 1.1E-76 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_04395 d0ebe0505aa7835fb9a6af25c204c084 358 SUPERFAMILY SSF48452 48 183 3.07E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_00090 a51234e4b7921c6617ee749ba075fb96 110 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 3 96 9.9E-23 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A3L12_00240 1ca8aec4b8e07313e278d87197c9a69a 197 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 14 186 2.0E-25 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L12_00240 1ca8aec4b8e07313e278d87197c9a69a 197 Gene3D G3DSA:3.40.50.11570 7 196 4.9E-34 T 23-10-2018 A3L12_07240 2c7933cc51a84f8da114d35423c3d9a1 189 Pfam PF06197 Protein of unknown function (DUF998) 12 181 1.9E-21 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L12_05225 e01b4a276ca9e0840ce52b8547c0dce9 199 Pfam PF02517 CAAX protease self-immunity 110 187 1.4E-8 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L12_03425 4e670373d85627f4889ee117ae014144 219 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 54 1.0E-14 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L12_03425 4e670373d85627f4889ee117ae014144 219 Pfam PF04256 Protein of unknown function (DUF434) 2 56 1.2E-23 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L12_07355 fe050c4b6dd244627400894edd2c935c 345 SUPERFAMILY SSF53335 156 345 1.1E-8 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L12_03645 f1d51a4af9465a86eff25f2c9dc253ef 120 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 1.2E-24 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A3L12_08140 80fe92a3c6ffbaeef2dd20a3abe3e87c 183 Pfam PF08463 EcoEI R protein C-terminal 20 176 2.4E-22 T 23-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 A3L12_00325 748bb5865079c6d6e54cf8493ec9fa79 377 Pfam PF04123 Domain of unknown function (DUF373) 6 348 1.9E-97 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A3L12_03735 277196d355f1e756b29f982a3338d716 234 Pfam PF07758 Protein of unknown function (DUF1614) 56 233 9.5E-56 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 A3L12_05625 6e56be5f3ca681aca5f39d320ec081f8 193 Pfam PF01944 Stage II sporulation protein M 18 188 5.8E-32 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L12_05895 1e73fac69c323dc08ca813d6b0768835 192 Gene3D G3DSA:3.60.21.10 14 136 2.3E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L12_05895 1e73fac69c323dc08ca813d6b0768835 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 149 2.6E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L12_05895 1e73fac69c323dc08ca813d6b0768835 192 SUPERFAMILY SSF56300 22 156 2.46E-19 T 23-10-2018 A3L12_00400 e99b493cac446f6915f1f36217098a2b 130 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 8 122 1.2E-7 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L12_07885 9ec55b7e4071306f4b773d4e6e43c1b6 131 Gene3D G3DSA:1.10.10.60 84 128 7.2E-8 T 23-10-2018 A3L12_07885 9ec55b7e4071306f4b773d4e6e43c1b6 131 SUPERFAMILY SSF46689 84 124 1.03E-6 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L12_05960 cf3564529ee04452e2ce71e7f7749415 93 SUPERFAMILY SSF88723 2 92 5.33E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L12_05960 cf3564529ee04452e2ce71e7f7749415 93 Gene3D G3DSA:3.40.50.1010 1 87 1.1E-16 T 23-10-2018 A3L12_05960 cf3564529ee04452e2ce71e7f7749415 93 Pfam PF01850 PIN domain 2 85 2.8E-13 T 23-10-2018 IPR002716 PIN domain A3L12_06995 17b42b8db9530b86d69a2225b71cfa84 251 Pfam PF02361 Cobalt transport protein 11 207 1.7E-26 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L12_04010 0e35fb03b34f132d0f24c8c5b7e4de5f 320 Pfam PF01384 Phosphate transporter family 19 307 2.9E-69 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L12_05370 01829fac478ba6c31c75b417cd8e9d28 243 Pfam PF01925 Sulfite exporter TauE/SafE 8 240 8.4E-56 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L12_01155 7ee35c65b13c2f1f178407fd257bf266 269 Pfam PF02535 ZIP Zinc transporter 124 264 8.3E-19 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L12_07640 20d974eff3033335d967d7dd3d23cefa 394 Pfam PF03222 Tryptophan/tyrosine permease family 65 391 5.7E-28 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L12_07765 ae8a4aecf72a00d7fbd3ffff151bfad8 260 Pfam PF14378 PAP2 superfamily 63 213 1.1E-11 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 A3L12_07765 ae8a4aecf72a00d7fbd3ffff151bfad8 260 Gene3D G3DSA:1.20.144.10 143 240 1.0E-5 T 23-10-2018 A3L12_07765 ae8a4aecf72a00d7fbd3ffff151bfad8 260 SUPERFAMILY SSF48317 68 223 1.96E-7 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L12_06465 6fdcbd545b544701f8fce0989d3681d8 150 Pfam PF01927 Mut7-C RNAse domain 1 139 2.8E-40 T 23-10-2018 IPR002782 Mut7-C RNAse domain A3L12_06355 638c9e4e51a36f1bd6f1f10f39be54bb 191 Pfam PF04434 SWIM zinc finger 46 69 3.3E-6 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A3L12_07615 7a10bc7391a3fcb8476b7a9b65165532 185 Gene3D G3DSA:3.40.5.50 132 184 4.6E-22 T 23-10-2018 A3L12_07615 7a10bc7391a3fcb8476b7a9b65165532 185 Gene3D G3DSA:1.20.58.1030 1 113 4.3E-42 T 23-10-2018 A3L12_04860 f0987c188cb292afe8cef1dbc673db4e 197 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 1.6E-45 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A3L12_02400 87dcf000b9f7e637d1fd9dbb33739874 176 Pfam PF03692 Putative zinc- or iron-chelating domain 16 107 8.8E-18 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L12_02825 bae8b313f0c5a42a2ec36f3ae4b7883b 429 Pfam PF01882 Protein of unknown function DUF58 179 262 7.7E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L12_06635 194163f5a82ce96f1999600d60533eb8 393 Pfam PF04122 Putative cell wall binding repeat 2 108 203 4.4E-5 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L12_05525 4f40f5cc6035f461a639e3044fe0ab0f 240 Pfam PF01940 Integral membrane protein DUF92 11 214 6.0E-52 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A3L12_04300 e197662bc2807c76959e399a2e64b2ff 76 Pfam PF13244 Domain of unknown function (DUF4040) 11 75 5.3E-13 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L12_05975 ed7152d1f5af7e2e8d158880bd07a7b7 234 Pfam PF12698 ABC-2 family transporter protein 51 229 2.1E-9 T 23-10-2018 A3L12_04915 885841d06ecf2017b57ed2b1c1787458 294 Pfam PF03186 CobD/Cbib protein 8 268 3.0E-85 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L12_04915 885841d06ecf2017b57ed2b1c1787458 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 288 3.1E-84 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L12_04915 885841d06ecf2017b57ed2b1c1787458 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 292 81.085 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L12_00860 9a26ece5abb1dccbb552e6fedb6bd9af 431 Gene3D G3DSA:1.25.40.10 265 407 6.5E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_00860 9a26ece5abb1dccbb552e6fedb6bd9af 431 Gene3D G3DSA:1.25.40.10 1 169 1.4E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L12_01115 9cc6611e94863e82e26cffe9f73d7278 324 Pfam PF01901 Putative O-antigen polymerase 3 311 3.7E-58 T 23-10-2018 IPR002760 Putative O-antigen polymerase A3L12_06885 bec3f6436572daf973a49204a5fcd143 183 Pfam PF06197 Protein of unknown function (DUF998) 15 176 1.7E-12 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L12_01840 63c52494185f8a6f478fe7684ce41229 59 Gene3D G3DSA:3.30.300.20 5 58 1.3E-8 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L12_01840 63c52494185f8a6f478fe7684ce41229 59 SUPERFAMILY SSF54814 12 57 9.16E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L12_08060 023a610b9f0553cd5fff848e3fe054e5 97 Gene3D G3DSA:1.10.287.1080 1 79 1.4E-29 T 23-10-2018 A3L12_08060 023a610b9f0553cd5fff848e3fe054e5 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 78 4.6E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L12_08060 023a610b9f0553cd5fff848e3fe054e5 97 SUPERFAMILY SSF101386 1 79 4.09E-22 T 23-10-2018 A3L12_07600 6ecf0768833150250334b7d9544904a7 475 SUPERFAMILY SSF101960 39 468 1.7E-123 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L12_07600 6ecf0768833150250334b7d9544904a7 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 30 464 1.6E-188 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A3L12_07600 6ecf0768833150250334b7d9544904a7 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 1.1E-64 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L12_07535 99eb6b88b32a9fb683fdf5b7b1ed8256 570 Pfam PF00482 Type II secretion system (T2SS), protein F 85 212 6.0E-10 T 23-10-2018 IPR018076 Type II secretion system F domain A3L12_07535 99eb6b88b32a9fb683fdf5b7b1ed8256 570 Pfam PF00482 Type II secretion system (T2SS), protein F 334 457 1.2E-10 T 23-10-2018 IPR018076 Type II secretion system F domain A3L12_02590 eb603eeea631b112ca5f236343792c24 102 Gene3D G3DSA:3.30.720.70 1 102 1.6E-41 T 23-10-2018 A3L12_06335 27e5cbac053c266a807e1173f6957b47 99 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 8 40 7.0E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A3L12_00880 63e1858b137df7373bd1500ee5764b0e 165 Pfam PF03692 Putative zinc- or iron-chelating domain 25 130 3.3E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L12_05260 93c9c10d42cd8765d011e8b5fcbc04c8 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 332 4.4E-39 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L12_05985 bcd1d93aff9d6128dbfc74c916bac73e 259 ProDom PD039347 PF1398 MJ0538 PH1392 1 240 1.0E-65 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A3L12_00265 01c9a3112a95eeb9a23e988701022663 204 Pfam PF01914 MarC family integral membrane protein 7 196 1.2E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L12_07820 1a75751191912cd26c3c73a5e00f4ad4 59 SUPERFAMILY SSF47113 8 59 1.49E-5 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L12_03655 105739d6c5af86125b4a75681d9ddf50 302 Pfam PF00953 Glycosyl transferase family 4 69 215 9.6E-33 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A3L12_03305 c99a212fc4d87ef222b6fa79f67a65c7 210 Pfam PF06510 Protein of unknown function (DUF1102) 39 198 2.7E-44 T 23-10-2018 IPR009482 Protein of unknown function DUF1102