locus-tag	class	description
A3L14_00035	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L14_00035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_00045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L14_00055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L14_00125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L14_00155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L14_00160	COG0402	S-adenosylhomocysteine deaminase activity
A3L14_00165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L14_00165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L14_00180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L14_00180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L14_00205	COG0640	Transcriptional regulator
A3L14_00235	COG0308	aminopeptidase N
A3L14_00250	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L14_00270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L14_00270	COG0116	Belongs to the methyltransferase superfamily
A3L14_00275	COG1160	GTP binding
A3L14_00310	COG1047	Peptidyl-prolyl cis-trans
A3L14_00335	COG0714	Associated with various cellular activities
A3L14_00355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L14_00370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L14_00400	COG0037	tRNA processing
A3L14_00405	COG0750	zinc metalloprotease
A3L14_00410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L14_00430	COG1216	Glycosyl transferase, family 2
A3L14_00430	COG0463	Glycosyl transferase, family 2
A3L14_00455	COG0110	maltose O-acetyltransferase activity
A3L14_00465	COG1086	Polysaccharide biosynthesis protein
A3L14_00485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L14_00490	COG0076	glutamate decarboxylase activity
A3L14_00520	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L14_00535	COG0037	tRNA processing
A3L14_00550	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L14_00560	COG0475	glutathione-regulated potassium exporter activity
A3L14_00620	COG0681	Belongs to the peptidase S26 family
A3L14_00630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_00640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L14_00675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L14_00680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L14_00685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L14_00690	COG0569	domain protein
A3L14_00700	COG1269	ATP hydrolysis coupled proton transport
A3L14_00710	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L14_00720	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L14_00725	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L14_00735	COG1394	ATPase activity, coupled to movement of substances
A3L14_00740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_00760	COG0601	transmembrane transport
A3L14_00765	COG1606	tRNA processing
A3L14_00785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3L14_00795	COG0601	transmembrane transport
A3L14_00800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L14_00805	COG0444	Belongs to the ABC transporter superfamily
A3L14_00810	COG4608	Belongs to the ABC transporter superfamily
A3L14_00830	COG0174	glutamine synthetase
A3L14_00855	COG0697	spore germination
A3L14_00870	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_00890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L14_00900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L14_00910	COG1297	OPT oligopeptide transporter protein
A3L14_00915	COG1234	tRNA 3'-trailer cleavage
A3L14_00920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L14_00930	COG3842	ATPase activity
A3L14_00940	COG3833	ABC-type maltose transport systems, permease component
A3L14_00945	COG1175	transmembrane transport
A3L14_00950	COG2182	Extracellular solute-binding protein
A3L14_00960	COG1378	Sugar-specific transcriptional regulator TrmB
A3L14_00995	COG0697	spore germination
A3L14_01005	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_01030	COG1373	ATPase (AAA superfamily
A3L14_01035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L14_01055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L14_01100	COG0714	Associated with various cellular activities
A3L14_01115	COG0463	Glycosyl transferase, family 2
A3L14_01120	COG1215	transferase activity, transferring glycosyl groups
A3L14_01130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L14_01165	COG0730	response to heat
A3L14_01195	COG2046	Belongs to the sulfate adenylyltransferase family
A3L14_01210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3L14_01260	COG1785	Belongs to the alkaline phosphatase family
A3L14_01315	COG0517	IMP dehydrogenase activity
A3L14_01315	COG0516	GMP reductase activity
A3L14_01320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L14_01330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L14_01340	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3L14_01345	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3L14_01350	COG3383	formate dehydrogenase (NAD+) activity
A3L14_01370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L14_01375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L14_01380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L14_01385	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L14_01390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L14_01395	COG0151	Belongs to the GarS family
A3L14_01410	COG0047	phosphoribosylformylglycinamidine synthase activity
A3L14_01425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L14_01435	COG0519	Catalyzes the synthesis of GMP from XMP
A3L14_01435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L14_01450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L14_01450	COG0519	Catalyzes the synthesis of GMP from XMP
A3L14_01500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L14_01515	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L14_01520	COG1404	Belongs to the peptidase S8 family
A3L14_01615	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_01625	COG2234	aminopeptidase activity
A3L14_01695	COG0393	Putative heavy-metal-binding
A3L14_01720	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_01725	COG2264	protein methyltransferase activity
A3L14_01740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_01740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L14_01745	COG0668	transmembrane transport
A3L14_01845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L14_01850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L14_01860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A3L14_01935	COG1178	ABC-type Fe3 transport system permease component
A3L14_01960	COG0011	TIGRFAM Protein of
A3L14_01965	COG2078	PFAM AMMECR1 domain protein
A3L14_01975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_01975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L14_01995	COG0417	DNA replication proofreading
A3L14_02050	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_02070	COG1695	Transcriptional regulator
A3L14_02075	COG2050	protein possibly involved in aromatic compounds catabolism
A3L14_02075	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_02090	COG4662	Binding-protein-dependent transport system inner membrane component
A3L14_02100	COG1335	isochorismatase
A3L14_02130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_02195	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_02200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3L14_02240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L14_02240	COG0517	IMP dehydrogenase activity
A3L14_02245	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L14_02250	COG5016	pyruvate
A3L14_02250	COG0511	ligase activity, forming carbon-carbon bonds
A3L14_02260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L14_02270	COG0305	Participates in initiation and elongation during chromosome replication
A3L14_02270	COG1372	Participates in initiation and elongation during chromosome replication
A3L14_02295	COG0430	RNA-3'-phosphate cyclase activity
A3L14_02375	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A3L14_02385	COG0543	2 iron, 2 sulfur cluster binding
A3L14_02415	COG0017	Asparaginyl-tRNA synthetase
A3L14_02430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L14_02475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L14_02480	COG0088	Forms part of the polypeptide exit tunnel
A3L14_02485	COG0089	rRNA binding
A3L14_02490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L14_02495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L14_02505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L14_02510	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L14_02515	COG0023	Translation Initiation Factor
A3L14_02525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L14_02530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L14_02535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L14_02545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L14_02555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L14_02560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3L14_02575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L14_02580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L14_02590	COG0200	Binds to the 23S rRNA
A3L14_02615	COG1102	Psort location Cytoplasmic, score
A3L14_02625	COG0300	oxidoreductase activity
A3L14_02630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L14_02645	COG2813	Specifically methylates the guanine in position
A3L14_02655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L14_02660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L14_02685	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L14_02690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L14_02715	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L14_02755	COG1522	sequence-specific DNA binding
A3L14_02765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L14_02780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L14_02800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L14_02805	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_02830	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L14_02835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L14_02840	COG1355	regulation of microtubule-based process
A3L14_02855	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L14_02870	COG1304	FMN binding
A3L14_02885	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L14_02915	COG0495	leucyl-tRNA aminoacylation
A3L14_02925	COG0006	proline dipeptidase activity
A3L14_02965	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A3L14_02985	COG0864	Transcriptional regulator
A3L14_03000	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L14_03005	COG0347	Belongs to the P(II) protein family
A3L14_03015	COG0733	neurotransmitter:sodium symporter activity
A3L14_03020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L14_03035	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L14_03040	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L14_03055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3L14_03065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L14_03070	COG0534	Mate efflux family protein
A3L14_03075	COG0534	Mate efflux family protein
A3L14_03080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L14_03080	COG0574	Belongs to the PEP-utilizing enzyme family
A3L14_03100	COG1404	Belongs to the peptidase S8 family
A3L14_03115	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_03140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L14_03165	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L14_03170	COG0409	Hydrogenase expression formation protein
A3L14_03175	COG0298	carbon dioxide binding
A3L14_03180	COG0746	molybdenum cofactor guanylyltransferase activity
A3L14_03190	COG0489	protein tyrosine kinase activity
A3L14_03210	COG3291	Pkd domain containing protein
A3L14_03210	COG4412	M6 family metalloprotease domain protein
A3L14_03215	COG1234	tRNA 3'-trailer cleavage
A3L14_03235	COG2140	Oxalate decarboxylase
A3L14_03255	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A3L14_03255	COG0662	Cupin 2, conserved barrel domain protein
A3L14_03275	COG1122	ATPase activity
A3L14_03290	COG0310	cobalt ion transport
A3L14_03305	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_03340	COG0436	Aminotransferase
A3L14_03345	COG2104	thiamine diphosphate biosynthetic process
A3L14_03375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L14_03390	COG0049	tRNA binding
A3L14_03410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L14_03415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L14_03420	COG0085	RNA polymerase activity
A3L14_03450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L14_03455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L14_03510	COG0584	glycerophosphoryl diester phosphodiesterase
A3L14_03515	COG0584	glycerophosphoryl diester phosphodiesterase
A3L14_03520	COG2814	Major facilitator Superfamily
A3L14_03525	COG2271	Major facilitator Superfamily
A3L14_03535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L14_03555	COG0058	SHG alpha-glucan phosphorylase activity
A3L14_03565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L14_03590	COG0717	Belongs to the dCTP deaminase family
A3L14_03615	COG0081	regulation of translation
A3L14_03620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L14_03700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L14_03730	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L14_03790	COG1042	CoA-binding domain protein
A3L14_03790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_03790	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L14_03810	COG1110	DNA topoisomerase II activity
A3L14_03835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L14_03845	COG0546	phosphoglycolate phosphatase activity
A3L14_03855	COG1418	mRNA catabolic process
A3L14_03865	COG0017	Asparaginyl-tRNA synthetase
A3L14_03880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3L14_03890	COG0585	pseudouridine synthase activity
A3L14_03895	COG0546	phosphoglycolate phosphatase activity
A3L14_03935	COG0504	CTP synthase activity
A3L14_03950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L14_03965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A3L14_03975	COG0516	GMP reductase activity
A3L14_03975	COG0517	IMP dehydrogenase activity
A3L14_03985	COG0024	Methionine aminopeptidase
A3L14_03990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L14_03995	COG1122	ATPase activity
A3L14_04035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L14_04050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L14_04170	COG0628	permease
A3L14_04175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L14_04195	COG1131	(ABC) transporter
A3L14_04205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A3L14_04210	COG0556	nucleotide-excision repair
A3L14_04215	COG0101	tRNA pseudouridine synthase activity
A3L14_04225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3L14_04230	COG1063	alcohol dehydrogenase
A3L14_04235	COG2894	cell division
A3L14_04265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L14_04270	COG0252	asparaginase activity
A3L14_04300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L14_04350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L14_04355	COG1085	galactose-1-phosphate uridylyltransferase
A3L14_04365	COG0038	chloride channel
A3L14_04380	COG0475	glutathione-regulated potassium exporter activity
A3L14_04395	COG0010	Belongs to the arginase family
A3L14_04400	COG1554	hydrolase, family 65, central catalytic
A3L14_04420	COG1175	transmembrane transport
A3L14_04425	COG3833	ABC-type maltose transport systems, permease component
A3L14_04430	COG3842	ATPase activity
A3L14_04435	COG0438	transferase activity, transferring glycosyl groups
A3L14_04510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L14_04520	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L14_04535	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L14_04550	COG4133	protoheme IX ABC transporter activity
A3L14_04580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L14_04580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L14_04595	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3L14_04595	COG0359	binds to the 23S rRNA
A3L14_04620	COG0573	inorganic phosphate transmembrane transporter activity
A3L14_04625	COG0581	inorganic phosphate transmembrane transporter activity
A3L14_04630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3L14_04640	COG0704	Plays a role in the regulation of phosphate uptake
A3L14_04690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_04715	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_04720	COG1881	PFAM PEBP family protein
A3L14_04765	COG1151	hydroxylamine reductase activity
A3L14_04825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_04830	COG0649	NAD binding
A3L14_04840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_04845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3L14_04855	COG0651	ATP synthesis coupled electron transport
A3L14_04860	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L14_04865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L14_04865	COG2111	Na H antiporter
A3L14_04875	COG1320	monovalent cation:proton antiporter activity
A3L14_04880	COG2212	antiporter activity
A3L14_04885	COG1863	multisubunit Na H antiporter MnhE subunit
A3L14_04915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L14_04940	COG0018	arginyl-trna synthetase
A3L14_04950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L14_05035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L14_05035	COG0301	tRNA thio-modification
A3L14_05040	COG1836	PFAM Integral membrane protein DUF92
A3L14_05045	COG1522	sequence-specific DNA binding
A3L14_05050	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L14_05075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A3L14_05125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L14_05135	COG1476	TRANSCRIPTIONal
A3L14_05155	COG0569	domain protein
A3L14_05175	COG1515	deoxyribonuclease V activity
A3L14_05185	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L14_05195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L14_05200	COG0501	Belongs to the peptidase M48B family
A3L14_05210	COG0436	Aminotransferase
A3L14_05215	COG2192	nodulation
A3L14_05225	COG0442	prolyl-tRNA aminoacylation
A3L14_05230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L14_05250	COG0730	response to heat
A3L14_05260	COG0730	response to heat
A3L14_05300	COG0720	synthase
A3L14_05325	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_05330	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_05330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L14_05350	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_05355	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_05355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L14_05370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L14_05380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L14_05445	COG0215	cysteine-tRNA ligase activity
A3L14_05485	COG0351	phosphomethylpyrimidine kinase
A3L14_05485	COG0352	thiamine-phosphate diphosphorylase activity
A3L14_05490	COG0352	thiamine-phosphate diphosphorylase activity
A3L14_05495	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A3L14_05500	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A3L14_05510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A3L14_05515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L14_05535	COG0534	Mate efflux family protein
A3L14_05540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_05545	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_05550	COG1201	RNA secondary structure unwinding
A3L14_05560	COG2001	Belongs to the MraZ family
A3L14_05570	COG1215	transferase activity, transferring glycosyl groups
A3L14_05700	COG1363	Peptidase, m42
A3L14_05710	COG2409	Drug exporters of the RND superfamily
A3L14_05745	COG2096	Adenosyltransferase
A3L14_05755	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_05770	COG1546	Belongs to the CinA family
A3L14_05770	COG1058	Belongs to the CinA family
A3L14_05785	COG1872	DUF167
A3L14_05830	COG0534	Mate efflux family protein
A3L14_05850	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L14_05865	COG0006	proline dipeptidase activity
A3L14_05900	COG0482	sulfurtransferase activity
A3L14_05915	COG1918	ferrous iron import across plasma membrane
A3L14_05915	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L14_05935	COG0163	prenyltransferase activity
A3L14_05950	COG0012	GTP binding
A3L14_05960	COG1794	racemase activity, acting on amino acids and derivatives
A3L14_05970	COG0312	modulator of DNA gyrase
A3L14_05980	COG2264	protein methyltransferase activity
A3L14_06000	COG0525	valine-tRNA ligase activity
A3L14_06030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L14_06035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L14_06040	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3L14_06060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3L14_06075	COG2342	PFAM TM1410 hypothetical-related protein
A3L14_06080	COG0746	molybdenum cofactor guanylyltransferase activity
A3L14_06090	COG1492	cobalamin metabolic process
A3L14_06095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3L14_06115	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3L14_06120	COG0303	'Molybdopterin
A3L14_06145	COG1078	dGTPase activity
A3L14_06155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_06185	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L14_06190	COG0493	'glutamate synthase
A3L14_06195	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_06200	COG1335	isochorismatase
A3L14_06205	COG0492	ferredoxin-NADP+ reductase activity
A3L14_06225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3L14_06235	COG0459	protein refolding
A3L14_06245	COG0515	serine threonine protein kinase
A3L14_06250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3L14_06260	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L14_06290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_06290	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L14_06315	COG0463	Glycosyl transferase, family 2
A3L14_06345	COG1739	Uncharacterized protein family UPF0029
A3L14_06350	COG1111	helicase
A3L14_06350	COG1205	dead DEAH box helicase
A3L14_06355	COG1129	ABC transporter
A3L14_06430	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L14_06455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L14_06460	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_06475	COG0051	transcription antitermination factor activity, RNA binding
A3L14_06480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L14_06490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L14_06495	COG1078	dGTPase activity
A3L14_06535	COG1469	GTP cyclohydrolase I activity
A3L14_06560	COG2205	protein histidine kinase activity
A3L14_06580	COG1121	(ABC) transporter
A3L14_06590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3L14_06635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L14_06650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L14_06655	COG0011	TIGRFAM Protein of
A3L14_06670	COG0563	adenylate kinase activity
A3L14_06685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L14_06735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L14_06740	COG1993	acr, cog1993
A3L14_06750	COG1794	racemase activity, acting on amino acids and derivatives
A3L14_06760	COG0312	modulator of DNA gyrase
A3L14_06765	COG0312	modulator of DNA gyrase
A3L14_06780	COG2814	Major facilitator Superfamily
A3L14_06785	COG0477	Major facilitator Superfamily
A3L14_06840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L14_06920	COG0243	molybdopterin cofactor binding
A3L14_06925	COG0450	alkyl hydroperoxide reductase
A3L14_06950	COG2217	Heavy metal translocating P-type atpase
A3L14_06955	COG1522	sequence-specific DNA binding
A3L14_06995	COG0626	cystathionine gamma-synthase activity
A3L14_07015	COG2217	Heavy metal translocating P-type atpase
A3L14_07025	COG0631	protein serine/threonine phosphatase activity
A3L14_07030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_07035	COG2815	serine threonine protein kinase
A3L14_07035	COG0515	serine threonine protein kinase
A3L14_07090	COG0456	acetyltransferase
A3L14_07105	COG2217	Heavy metal translocating P-type atpase
A3L14_07110	COG0640	Transcriptional regulator
A3L14_07115	COG0697	spore germination
A3L14_07140	COG0672	)-iron permease
A3L14_07145	COG0450	alkyl hydroperoxide reductase
A3L14_07155	COG1522	sequence-specific DNA binding
A3L14_07180	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_07210	COG0396	ATPase activity
A3L14_07220	COG0301	tRNA thio-modification
A3L14_07225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L14_07230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L14_07260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L14_07260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L14_07265	COG1012	belongs to the aldehyde dehydrogenase family
A3L14_07275	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_07285	COG0426	domain, Protein
A3L14_07295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L14_07300	COG1592	Rubrerythrin
A3L14_07305	COG1773	rubredoxin
A3L14_07310	COG2033	superoxide reductase activity
A3L14_07350	COG0735	belongs to the Fur family
A3L14_07420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3L14_07430	COG0131	Imidazoleglycerol-phosphate dehydratase
A3L14_07445	COG0107	imidazoleglycerol-phosphate synthase activity
A3L14_07450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A3L14_07450	COG0140	phosphoribosyl-ATP diphosphatase activity
A3L14_07455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L14_07465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L14_07470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L14_07485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_07495	COG1301	dicarboxylic acid transport
A3L14_07505	COG1830	Aldolase
A3L14_07510	COG5016	pyruvate
A3L14_07510	COG0511	ligase activity, forming carbon-carbon bonds
A3L14_07515	COG1966	Carbon starvation protein
A3L14_07530	COG0003	Pfam Anion-transporting ATPase
A3L14_07555	COG2267	carboxylic ester hydrolase activity
A3L14_07565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L14_07590	COG0489	protein tyrosine kinase activity
A3L14_07640	COG1342	Belongs to the UPF0251 family
A3L14_07650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L14_07675	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_07695	COG0477	Major facilitator Superfamily
A3L14_07715	COG1201	RNA secondary structure unwinding
A3L14_07725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L14_07730	COG5434	Belongs to the glycosyl hydrolase 28 family
A3L14_07740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L14_07755	COG0084	hydrolase, TatD family'
A3L14_07765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L14_07790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L14_07795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L14_07800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L14_07810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3L14_07820	COG0105	UTP biosynthetic process
A3L14_07860	COG0175	sulfate reduction
A3L14_07875	COG0402	S-adenosylhomocysteine deaminase activity
A3L14_07895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3L14_07935	COG0017	Asparaginyl-tRNA synthetase
A3L14_07945	COG4143	(ABC) transporter
A3L14_07965	COG1444	tRNA N-acetyltransferase activity
A3L14_07980	COG4946	Tricorn protease homolog
A3L14_07980	COG1506	peptidase
A3L14_07980	COG0823	Involved in the tonB-independent uptake of proteins
A3L14_08005	COG1268	BioY protein
A3L14_08010	COG1827	regulation of RNA biosynthetic process
A3L14_08015	COG1122	ATPase activity
A3L14_08020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3L14_08050	COG1522	sequence-specific DNA binding
A3L14_08070	COG1178	ABC-type Fe3 transport system permease component
A3L14_08075	COG3842	ATPase activity
A3L14_08085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3L14_08100	COG0126	phosphoglycerate kinase activity
A3L14_08130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L14_08170	COG1042	CoA-binding domain protein
A3L14_08170	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L14_08170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_08205	COG0301	tRNA thio-modification
A3L14_08215	COG0301	tRNA thio-modification
A3L14_08250	COG1489	DNA binding
A3L14_08325	COG0705	Rhomboid family
A3L14_08325	COG0457	Tetratricopeptide repeat
A3L14_08330	COG0483	inositol monophosphate 1-phosphatase activity
A3L14_08340	COG1454	alcohol dehydrogenase
A3L14_08350	COG1984	allophanate hydrolase subunit 2
A3L14_08355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L14_08360	COG1487	ribonuclease activity
A3L14_08370	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L14_08420	COG0330	HflC and HflK could
A3L14_08425	COG2894	cell division
A3L14_08440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L14_08455	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L14_08470	COG0513	Belongs to the DEAD box helicase family
A3L14_08495	COG1196	nuclear chromosome segregation
A3L14_08515	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_08515	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_08560	COG2894	cell division
A3L14_08570	COG0367	asparagine synthase
A3L14_08585	COG0009	L-threonylcarbamoyladenylate synthase
A3L14_08610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L14_08615	COG0303	'Molybdopterin
A3L14_08625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_08640	COG1042	CoA-binding domain protein
A3L14_08640	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L14_08720	COG1793	dna ligase
A3L14_08720	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L14_08730	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L14_08735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_08780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L14_08785	COG0778	Nitroreductase
A3L14_08805	COG0312	modulator of DNA gyrase
A3L14_08900	COG1056	cytidyltransferase-related domain
A3L14_08900	COG1051	belongs to the nudix hydrolase family
A3L14_08960	COG0560	Phosphoserine phosphatase
A3L14_08965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L14_08990	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L14_08995	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L14_09015	COG1160	GTP binding
A3L14_09020	COG0432	Pfam Uncharacterised protein family UPF0047
A3L14_09040	COG1832	CoA-binding protein
A3L14_09075	COG2379	hydroxypyruvate reductase
A3L14_09085	COG3842	ATPase activity
A3L14_09090	COG0581	inorganic phosphate transmembrane transporter activity
A3L14_09110	COG0673	inositol 2-dehydrogenase activity
A3L14_09115	COG0463	Glycosyl transferase, family 2
A3L14_09160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L14_09170	COG1850	ribulose-bisphosphate carboxylase activity
A3L14_09215	COG1131	(ABC) transporter
A3L14_09240	COG1213	nucleotidyl transferase
A3L14_09240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L14_09255	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L14_09265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L14_09265	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L14_09275	COG1192	Involved in chromosome partitioning
A3L14_09280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L14_09300	COG2119	membrane
A3L14_09330	COG1476	TRANSCRIPTIONal
A3L14_09335	COG1131	(ABC) transporter
A3L14_09395	COG0543	2 iron, 2 sulfur cluster binding
A3L14_09410	COG0509	glycine decarboxylation via glycine cleavage system
A3L14_09415	COG1863	multisubunit Na H antiporter MnhE subunit
A3L14_09420	COG2212	antiporter activity
A3L14_09450	COG0651	ATP synthesis coupled electron transport
A3L14_09455	COG0440	acetolactate synthase activity
A3L14_09475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L14_09505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L14_09575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L14_09605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_09610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L14_09615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L14_09625	COG1765	OsmC-like protein
A3L14_09630	COG2095	MarC family integral membrane protein
A3L14_09660	COG0693	protein deglycase activity
A3L14_09665	COG1522	sequence-specific DNA binding
A3L14_09670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L14_09690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L14_09710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L14_09720	COG2814	Major facilitator Superfamily
A3L14_09740	COG2723	6-phospho-beta-galactosidase activity
A3L14_09765	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_09780	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_09850	COG0167	dihydroorotate dehydrogenase activity
A3L14_09855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L14_09875	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_09880	COG1404	Belongs to the peptidase S8 family
A3L14_09900	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L14_09905	COG1141	Ferredoxin
A3L14_09930	COG0493	'glutamate synthase
A3L14_09935	COG0543	2 iron, 2 sulfur cluster binding
A3L14_09970	COG0501	Belongs to the peptidase M48B family
A3L14_09975	COG2131	deaminase
A3L14_09985	COG0546	phosphoglycolate phosphatase activity
A3L14_09990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3L14_10000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_10005	COG2271	Major facilitator Superfamily
A3L14_10030	COG1446	asparaginase
A3L14_10050	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L14_10100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3L14_10120	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_10150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_10165	COG2255	four-way junction helicase activity
A3L14_10170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3L14_10175	COG0156	8-amino-7-oxononanoate synthase activity
A3L14_10195	COG0456	acetyltransferase
A3L14_10195	COG1214	PFAM Peptidase M22, glycoprotease
A3L14_10200	COG0433	COG0433 Predicted ATPase
A3L14_10210	COG0419	ATPase involved in DNA repair
A3L14_10210	COG0419	ATPase involved in DNA repair
A3L14_10225	COG4139	cobalamin transport
A3L14_10230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L14_10260	COG2078	PFAM AMMECR1 domain protein
A3L14_10260	COG3885	ferrous iron binding
A3L14_10275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_10310	COG0432	Pfam Uncharacterised protein family UPF0047
A3L14_10325	COG0540	Belongs to the ATCase OTCase family
A3L14_10330	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L14_10385	COG0434	BtpA family
A3L14_10400	COG0714	Associated with various cellular activities
A3L14_10430	COG0312	modulator of DNA gyrase
A3L14_10435	COG0312	modulator of DNA gyrase
A3L14_10440	COG1846	Transcriptional regulator
A3L14_10455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L14_10490	COG0281	malic enzyme
A3L14_10505	COG1373	ATPase (AAA superfamily
A3L14_10510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3L14_10520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L14_10525	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A3L14_10530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L14_10565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L14_10570	COG0306	phosphate transporter
A3L14_10585	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_10590	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_10600	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_10605	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_10610	COG0489	protein tyrosine kinase activity
A3L14_10635	COG1131	(ABC) transporter
A3L14_10650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L14_10660	COG1254	Belongs to the acylphosphatase family
A3L14_10665	COG1324	tolerance protein
A3L14_10670	COG1628	Protein of unknown function DUF99
A3L14_10700	COG1980	fructose-bisphosphate aldolase activity
A3L14_10735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L14_10810	COG1522	sequence-specific DNA binding
A3L14_10830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3L14_10850	COG1757	Na H antiporter
A3L14_10855	COG1573	uracil-dna glycosylase
A3L14_10865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_10880	COG1380	Effector of murein hydrolase LrgA
A3L14_10885	COG1346	cytolysis
A3L14_10920	COG1404	Belongs to the peptidase S8 family
A3L14_11140	COG0095	Lipoate-protein ligase
A3L14_11170	COG2226	methyltransferase
A3L14_11175	COG1506	peptidase
A3L14_11175	COG0823	Involved in the tonB-independent uptake of proteins
A3L14_11175	COG4946	Tricorn protease homolog
A3L14_11200	COG0306	phosphate transporter
A3L14_11225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L14_11230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L14_11240	COG2212	antiporter activity
A3L14_11245	COG1320	monovalent cation:proton antiporter activity
A3L14_11270	COG0651	ATP synthesis coupled electron transport
A3L14_11280	COG3260	NADH ubiquinone oxidoreductase 20
A3L14_11285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_11285	COG0649	NAD binding
A3L14_11285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_11295	COG0650	Formate hydrogenlyase subunit 4
A3L14_11300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_11310	COG2212	antiporter activity
A3L14_11315	COG1320	monovalent cation:proton antiporter activity
A3L14_11330	COG2111	Na H antiporter
A3L14_11335	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L14_11340	COG0651	ATP synthesis coupled electron transport
A3L14_11350	COG3260	NADH ubiquinone oxidoreductase 20
A3L14_11355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_11355	COG0649	NAD binding
A3L14_11365	COG0650	Formate hydrogenlyase subunit 4
A3L14_11420	COG0492	ferredoxin-NADP+ reductase activity
A3L14_11435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L14_11460	COG0148	phosphopyruvate hydratase activity
A3L14_11475	COG1522	sequence-specific DNA binding
A3L14_11480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3L14_11500	COG0314	molybdopterin synthase activity