A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Pfam PF09210 Domain of unknown function (DUF1957) 427 526 4.8E-27 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Gene3D G3DSA:1.10.150.20 614 669 1.4E-13 T 23-10-2018 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 SUPERFAMILY SSF47794 616 667 1.96E-7 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 SUPERFAMILY SSF88688 416 531 3.6E-31 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Gene3D G3DSA:3.20.110.10 1 416 7.3E-180 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 SUPERFAMILY SSF88713 2 416 2.43E-120 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Pfam PF03065 Glycosyl hydrolase family 57 6 371 2.5E-72 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Pfam PF14520 Helix-hairpin-helix domain 616 662 4.5E-10 T 23-10-2018 A3L14_03000 f7a695c220c075e5adea67b0d9cc9f1f 669 Gene3D G3DSA:1.20.1430.10 417 563 4.1E-56 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.170.16.10 1094 1230 7.7E-33 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00350 101 533 1.9E-25 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:3.10.28.10 747 928 4.3E-16 T 23-10-2018 IPR027434 Homing endonuclease A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.170.16.10 1424 1489 3.3E-9 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.170.16.10 531 664 3.4E-19 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.20.28.10 132 177 2.4E-28 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF14890 Intein splicing domain 1096 1492 4.5E-23 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF51294 363 504 1.57E-21 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF51294 1090 1493 6.08E-30 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 521 535 4.0E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 320 335 4.0E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:1.10.10.10 1677 1762 9.4E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF55608 846 939 6.32E-8 T 23-10-2018 IPR027434 Homing endonuclease A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 611 624 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 1469 1486 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 751 763 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 855 867 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 1282 1297 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 PRINTS PR00379 Intein signature 1487 1496 6.6E-17 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:3.30.1640.10 1 100 6.3E-38 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF51294 532 1064 2.16E-33 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00305 1450 1498 7.5E-5 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00305 1024 1070 9.1E-13 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00305 459 509 6.5E-7 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 363 448 3.6E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1094 1184 5.6E-14 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 532 622 1.6E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF00493 MCM2/3/5 family 1065 1088 6.0E-7 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF00493 MCM2/3/5 family 266 383 9.4E-37 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF00493 MCM2/3/5 family 1491 1672 6.3E-65 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:3.40.50.300 1490 1676 9.3E-69 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:3.40.50.300 263 381 6.2E-39 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF14551 MCM N-terminal domain 8 93 3.8E-12 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF52540 1491 1669 6.29E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 482 504 1.4E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1471 1493 5.0E-5 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1043 1065 1.9E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00306 361 466 1.7E-12 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00306 1086 1207 1.4E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SMART SM00306 530 646 1.9E-15 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF17207 MCM OB domain 105 230 5.2E-35 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF52540 290 531 2.66E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.40.50.140 178 257 5.2E-26 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.170.16.10 931 1059 3.8E-11 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:2.170.16.10 382 503 1.9E-18 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Pfam PF14890 Intein splicing domain 539 1064 2.4E-29 T 23-10-2018 A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 SUPERFAMILY SSF50249 9 248 2.74E-61 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_02270 1c26ea1fef1b1170438a0e09c050befd 1762 Gene3D G3DSA:3.40.50.300 1060 1093 2.8E-8 T 23-10-2018 A3L14_08820 e621e3d2cc2a6e6e903f2997f8ad8702 234 Gene3D G3DSA:3.40.50.150 8 219 1.2E-37 T 23-10-2018 A3L14_08820 e621e3d2cc2a6e6e903f2997f8ad8702 234 SUPERFAMILY SSF53335 12 225 1.01E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_08820 e621e3d2cc2a6e6e903f2997f8ad8702 234 Pfam PF13649 Methyltransferase domain 50 144 2.2E-22 T 23-10-2018 A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 PIRSF PIRSF005650 1 225 9.4E-60 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 SUPERFAMILY SSF53633 1 224 5.11E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 Pfam PF00696 Amino acid kinase family 1 202 4.0E-33 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 3.4E-85 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.688 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L14_09810 6adc986688c88b64dd947e0b9b8f2934 225 Gene3D G3DSA:3.40.1160.10 1 225 6.9E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 3.1E-17 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 4.8E-21 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 SMART SM00529 25 124 8.5E-42 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 Gene3D G3DSA:1.10.10.10 3 68 1.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 Gene3D G3DSA:1.10.60.10 69 124 7.4E-20 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 SUPERFAMILY SSF47979 64 136 8.37E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L14_01910 ebb7509abbda6ef2a9c167393d3e58d1 145 SUPERFAMILY SSF46785 4 63 1.29E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02500 01fa5072e509f240afedacee092b07a9 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.309 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02500 01fa5072e509f240afedacee092b07a9 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 2.5E-65 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02500 01fa5072e509f240afedacee092b07a9 156 SUPERFAMILY SSF54843 8 153 8.76E-46 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02500 01fa5072e509f240afedacee092b07a9 156 Gene3D G3DSA:3.90.470.10 6 156 1.0E-52 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02500 01fa5072e509f240afedacee092b07a9 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 7.0E-34 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A3L14_02500 01fa5072e509f240afedacee092b07a9 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 PRINTS PR00141 Proteasome component signature 146 157 1.2E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 PRINTS PR00141 Proteasome component signature 135 146 1.2E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 PRINTS PR00141 Proteasome component signature 15 30 1.2E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 Pfam PF00227 Proteasome subunit 5 186 1.7E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.196 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 Gene3D G3DSA:3.60.20.10 8 200 3.8E-60 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 SUPERFAMILY SSF56235 2 193 4.89E-58 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_10240 b1e8dd7aeb3980d1f1343ada06fa387e 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 2.5E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L14_03130 a27d5af1fb36532c70fa849593335c61 377 SUPERFAMILY SSF111331 97 174 1.8E-7 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L14_03130 a27d5af1fb36532c70fa849593335c61 377 Gene3D G3DSA:3.40.50.10330 88 207 3.3E-5 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L14_03130 a27d5af1fb36532c70fa849593335c61 377 PIRSF PIRSF016907 1 377 8.9E-150 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A3L14_03130 a27d5af1fb36532c70fa849593335c61 377 ProDom PD125086 DNA GP2 END PROTECTOR TERMINAL GP2-LIKE T4 ENDS PROTECTS PROTECTING 260 363 4.0E-4 T 23-10-2018 A3L14_03130 a27d5af1fb36532c70fa849593335c61 377 Pfam PF01513 ATP-NAD kinase 2 376 2.5E-48 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 SUPERFAMILY SSF52743 211 508 1.31E-79 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 272 282 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 236 247 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 447 457 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 Pfam PF00082 Subtilase family 231 490 7.2E-50 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 Gene3D G3DSA:3.40.50.200 203 510 2.3E-82 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 268 281 5.6E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 231 250 5.6E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_10920 9a07a7fda3b28934033b0255fc750099 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 446 462 5.6E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:1.10.8.60 416 505 2.2E-17 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:1.10.8.60 684 792 6.0E-33 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SMART SM01073 8 92 1.8E-43 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:1.10.8.60 350 404 1.1E-81 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:3.40.50.300 179 349 1.1E-81 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SMART SM00382 549 685 6.7E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SMART SM00382 215 351 1.3E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 2.3E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 553 682 1.8E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SUPERFAMILY SSF50692 2 91 2.49E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 2.6E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SMART SM01072 107 170 1.0E-17 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SUPERFAMILY SSF52540 511 790 3.55E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:3.40.50.300 508 682 1.9E-75 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 ProSitePatterns PS00674 AAA-protein family signature. 653 671 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 3.1E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SUPERFAMILY SSF52540 179 501 2.46E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:2.40.40.20 1 92 5.3E-37 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 Gene3D G3DSA:3.10.330.10 93 173 1.9E-7 T 23-10-2018 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 792 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L14_08735 7d31cee7b7e02b71ab57da511e4c15c6 795 SUPERFAMILY SSF54585 92 184 1.96E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 1.0E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 SUPERFAMILY SSF54909 62 141 5.36E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 SMART SM00344 2 108 7.3E-47 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 Gene3D G3DSA:1.10.10.10 1 52 2.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 3.0E-14 T 23-10-2018 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 9.0E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 9.0E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 9.0E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 Gene3D G3DSA:3.30.70.920 65 141 1.4E-19 T 23-10-2018 A3L14_10810 0b4983aa7bfe801ad9a61be049ce924a 141 SUPERFAMILY SSF46785 1 62 1.6E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08565 473e1b2686334b78c6a5edeba5838c33 247 Gene3D G3DSA:3.40.50.300 1 243 9.4E-56 T 23-10-2018 A3L14_08565 473e1b2686334b78c6a5edeba5838c33 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 239 1.3E-49 T 23-10-2018 IPR004130 GPN-loop GTPase A3L14_08565 473e1b2686334b78c6a5edeba5838c33 247 SUPERFAMILY SSF52540 1 238 7.87E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 Gene3D G3DSA:3.40.50.300 1 181 5.6E-37 T 23-10-2018 A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 SUPERFAMILY SSF52540 2 182 2.11E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 1.8E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 175 1.8E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 3.0E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09015 0b6e41ce4e639e0c212b7af7b0db0c95 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 80 3.0E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SUPERFAMILY SSF50447 259 375 7.66E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Gene3D G3DSA:3.30.70.240 466 718 6.5E-75 T 23-10-2018 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SMART SM00889 506 619 4.3E-20 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.732 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SUPERFAMILY SSF52540 10 261 1.67E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Pfam PF00679 Elongation factor G C-terminus 621 704 4.2E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Gene3D G3DSA:2.40.30.10 259 386 2.9E-27 T 23-10-2018 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.0E-14 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Pfam PF14492 Elongation Factor G, domain II 387 459 5.8E-26 T 23-10-2018 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Gene3D G3DSA:3.40.50.300 7 222 1.5E-73 T 23-10-2018 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SMART SM00838 621 708 4.0E-43 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SUPERFAMILY SSF54980 388 463 4.32E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Gene3D G3DSA:3.30.70.870 388 465 4.9E-27 T 23-10-2018 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Gene3D G3DSA:3.30.230.10 472 720 6.5E-75 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SUPERFAMILY SSF54980 624 717 1.41E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 1.7E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 Pfam PF03764 Elongation factor G, domain IV 513 619 6.3E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 SUPERFAMILY SSF54211 463 623 6.57E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_06490 9ef8cfce9b47d9512f342136da5f071e 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 2.7E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_07955 56e2319041a8cb2e1e8dc92aca44a9a9 171 Gene3D G3DSA:3.40.50.1010 20 164 6.5E-13 T 23-10-2018 A3L14_07955 56e2319041a8cb2e1e8dc92aca44a9a9 171 Pfam PF01936 NYN domain 31 162 1.7E-21 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L14_07955 56e2319041a8cb2e1e8dc92aca44a9a9 171 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 17 163 7.8E-65 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L14_07955 56e2319041a8cb2e1e8dc92aca44a9a9 171 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 30 103 3.0E-31 T 23-10-2018 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 Gene3D G3DSA:3.20.20.70 1 225 2.6E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 SUPERFAMILY SSF51351 4 223 1.1E-47 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 168 216 7.8E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.915 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 Pfam PF00121 Triosephosphate isomerase 8 115 8.8E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_00085 fa57210c679a4d91610d3c8844136ada 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 3.8E-61 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 1.7E-10 T 23-10-2018 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.7E-10 T 23-10-2018 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 1.7E-10 T 23-10-2018 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 424 449 2.2E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 SUPERFAMILY SSF56425 205 309 1.64E-31 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 Gene3D G3DSA:3.50.50.60 6 355 1.4E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 321 339 4.4E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.4E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 SUPERFAMILY SSF51905 6 364 3.0E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 448 3.7E-157 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 Gene3D G3DSA:3.90.700.10 213 303 1.4E-111 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 Gene3D G3DSA:1.20.58.100 368 462 5.7E-19 T 23-10-2018 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 Pfam PF00890 FAD binding domain 6 348 1.5E-70 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L14_01320 f45890beb29c5fa366bb5f47569fe17b 466 SUPERFAMILY SSF46977 387 452 3.66E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Gene3D G3DSA:3.40.50.300 162 320 3.4E-43 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Gene3D G3DSA:3.40.50.300 20 132 1.5E-30 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 517 536 1.3E-29 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 67 86 1.3E-29 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 570 588 1.3E-29 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 456 1.3E-29 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 547 566 1.3E-29 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Gene3D G3DSA:1.10.8.60 321 413 8.1E-44 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 SMART SM00382 59 322 1.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Pfam PF01078 Magnesium chelatase, subunit ChlI 41 93 1.1E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 SUPERFAMILY SSF52540 36 414 3.2E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 24 629 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 434 615 2.8E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Pfam PF13654 AAA domain 183 411 1.2E-22 T 23-10-2018 A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 Gene3D G3DSA:3.30.230.10 432 635 4.6E-79 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_05075 2382bedfd521a6111dbc15c731deec96 635 SUPERFAMILY SSF54211 440 613 9.86E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 SUPERFAMILY SSF161111 4 202 2.09E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 SUPERFAMILY SSF160240 205 280 2.75E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 Gene3D G3DSA:1.20.1510.10 4 200 9.2E-63 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 280 6.6E-24 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 7.7E-82 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 Gene3D G3DSA:3.30.70.1350 207 282 2.1E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L14_00485 0d76b6f1f1c5e057666d2a3312ffb97a 286 Pfam PF01545 Cation efflux family 8 200 3.9E-46 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 3.8E-56 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Gene3D G3DSA:3.30.1490.70 70 241 1.7E-69 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 SUPERFAMILY SSF56091 63 242 2.67E-39 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Gene3D G3DSA:3.30.70.3350 244 374 4.1E-38 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 3.7E-147 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Gene3D G3DSA:2.20.25.320 7 67 3.0E-21 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Gene3D G3DSA:3.30.70.3360 314 362 4.1E-38 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Gene3D G3DSA:3.30.470.30 96 197 1.7E-69 T 23-10-2018 A3L14_02445 cf9fb98e4fa4b4fc4d0179c8993f0ad5 380 Pfam PF09414 RNA ligase 86 240 7.5E-18 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 A3L14_03190 597f49e6b69b588dc810a9125bcc4819 243 Gene3D G3DSA:3.40.50.300 1 223 4.0E-64 T 23-10-2018 A3L14_03190 597f49e6b69b588dc810a9125bcc4819 243 Hamap MF_02040 Iron-sulfur cluster carrier protein. 9 237 27.28 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L14_03190 597f49e6b69b588dc810a9125bcc4819 243 SUPERFAMILY SSF52540 9 217 5.13E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03190 597f49e6b69b588dc810a9125bcc4819 243 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 17 225 2.0E-53 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 585 597 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Pfam PF11897 Protein of unknown function (DUF3417) 15 122 2.4E-33 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Pfam PF00343 Carbohydrate phosphorylase 272 611 1.7E-26 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Pfam PF00343 Carbohydrate phosphorylase 126 173 8.2E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 SUPERFAMILY SSF53756 15 724 9.03E-207 T 23-10-2018 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 PIRSF PIRSF000460 3 768 4.3E-275 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Gene3D G3DSA:3.40.50.2000 116 183 1.1E-10 T 23-10-2018 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 109 691 8.9E-254 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Gene3D G3DSA:3.40.50.2000 269 405 2.9E-8 T 23-10-2018 A3L14_03555 68ee3eba7e4d5245a306a34cb028cd2c 831 Gene3D G3DSA:3.40.50.2000 406 730 3.4E-44 T 23-10-2018 A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 SUPERFAMILY SSF53271 234 439 4.98E-67 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 Gene3D G3DSA:3.60.20.10 5 438 4.4E-141 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 PIRSF PIRSF000485 1 441 4.6E-156 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 438 7.9E-157 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 437 44.123 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 Pfam PF00156 Phosphoribosyl transferase domain 265 369 7.7E-7 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 SUPERFAMILY SSF56235 5 240 1.8E-52 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 Pfam PF13537 Glutamine amidotransferase domain 72 199 9.4E-18 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L14_01370 a15ba19f3c93e4dd31abfdabb816a1c2 444 Gene3D G3DSA:3.40.50.2020 258 422 4.4E-141 T 23-10-2018 A3L14_02915 779c9953648bb746373cc09083cd3853 967 SUPERFAMILY SSF52374 4 694 3.07E-100 T 23-10-2018 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Gene3D G3DSA:3.30.2320.20 835 967 1.1E-46 T 23-10-2018 A3L14_02915 779c9953648bb746373cc09083cd3853 967 SUPERFAMILY SSF47323 714 881 3.18E-38 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Gene3D G3DSA:3.40.50.620 9 688 1.3E-299 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_02915 779c9953648bb746373cc09083cd3853 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 859 4.5E-31 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Gene3D G3DSA:1.10.10.720 866 917 1.1E-46 T 23-10-2018 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 1.5E-67 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.337 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Gene3D G3DSA:1.10.730.10 690 810 3.2E-35 T 23-10-2018 A3L14_02915 779c9953648bb746373cc09083cd3853 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 967 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_02915 779c9953648bb746373cc09083cd3853 967 SUPERFAMILY SSF50677 210 443 2.79E-33 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_02915 779c9953648bb746373cc09083cd3853 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_02915 779c9953648bb746373cc09083cd3853 967 Gene3D G3DSA:3.90.740.10 205 451 1.3E-299 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_07265 71607e210c028cf4c49758e7a6bce68a 506 Pfam PF00171 Aldehyde dehydrogenase family 39 493 8.7E-122 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A3L14_07265 71607e210c028cf4c49758e7a6bce68a 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A3L14_07265 71607e210c028cf4c49758e7a6bce68a 506 Gene3D G3DSA:3.40.605.10 40 269 7.5E-132 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A3L14_07265 71607e210c028cf4c49758e7a6bce68a 506 SUPERFAMILY SSF53720 21 499 1.96E-131 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A3L14_07265 71607e210c028cf4c49758e7a6bce68a 506 Gene3D G3DSA:3.40.309.10 270 469 7.5E-132 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 SUPERFAMILY SSF48239 306 511 1.59E-22 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Gene3D G3DSA:1.50.10.20 377 525 6.0E-15 T 23-10-2018 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Gene3D G3DSA:1.50.10.20 107 182 3.0E-6 T 23-10-2018 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 SUPERFAMILY SSF48239 68 289 3.93E-22 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Gene3D G3DSA:1.50.10.20 275 360 1.9E-8 T 23-10-2018 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Gene3D G3DSA:1.50.10.20 44 106 2.6E-8 T 23-10-2018 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 74 102 0.027 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 443 460 7.8 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L14_01505 a620ae6f3652f53c1bd038ceccd25f0e 739 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 309 338 0.0021 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A3L14_03850 67c768a5098e19a702676baa6d38faf5 269 Pfam PF14336 Domain of unknown function (DUF4392) 4 260 8.2E-64 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L14_03850 67c768a5098e19a702676baa6d38faf5 269 Gene3D G3DSA:3.90.1640.20 1 269 8.0E-99 T 23-10-2018 A3L14_01695 567e7f5539ef16cef36149aa672119e7 111 Gene3D G3DSA:3.30.110.70 4 111 2.3E-32 T 23-10-2018 A3L14_01695 567e7f5539ef16cef36149aa672119e7 111 Pfam PF01906 Putative heavy-metal-binding 5 106 3.7E-36 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L14_01695 567e7f5539ef16cef36149aa672119e7 111 SUPERFAMILY SSF117782 4 108 1.07E-35 T 23-10-2018 IPR035439 UPF0145 domain superfamily A3L14_01695 567e7f5539ef16cef36149aa672119e7 111 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 4 106 24.45 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 Gene3D G3DSA:3.40.50.620 213 478 5.8E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_08570 794052f8b655bc60a849a39096120ba3 479 SUPERFAMILY SSF52402 217 457 3.75E-57 T 23-10-2018 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 Pfam PF00733 Asparagine synthase 228 360 2.0E-32 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 Pfam PF00733 Asparagine synthase 365 458 4.7E-21 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 PIRSF PIRSF001589 363 478 3.4E-19 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 PIRSF PIRSF001589 1 376 4.2E-57 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 362 2.4E-81 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L14_08570 794052f8b655bc60a849a39096120ba3 479 SUPERFAMILY SSF56235 12 204 2.83E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_08570 794052f8b655bc60a849a39096120ba3 479 Pfam PF13537 Glutamine amidotransferase domain 61 179 1.7E-25 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L14_08570 794052f8b655bc60a849a39096120ba3 479 Gene3D G3DSA:3.60.20.10 2 212 3.5E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_02420 94dac010b8b718626a2ecce34a4e23c8 193 SUPERFAMILY SSF52540 19 169 1.97E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02420 94dac010b8b718626a2ecce34a4e23c8 193 Pfam PF00437 Type II/IV secretion system protein 7 114 2.8E-7 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L14_02420 94dac010b8b718626a2ecce34a4e23c8 193 Gene3D G3DSA:3.40.50.300 5 189 2.9E-15 T 23-10-2018 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 PIRSF PIRSF037016 37 393 1.0E-59 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 PIRSF PIRSF037016 389 416 0.0033 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.017 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 Gene3D G3DSA:1.10.1510.30 171 256 9.7E-116 T 23-10-2018 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 412 1.2E-131 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 SUPERFAMILY SSF55120 7 414 4.75E-90 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 Gene3D G3DSA:3.30.70.3160 44 125 9.7E-116 T 23-10-2018 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 11 415 1.8E-82 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A3L14_03890 e7359c76e64b302ea43aac590b36674a 416 Gene3D G3DSA:3.30.2350.20 126 411 9.7E-116 T 23-10-2018 A3L14_10320 16e799a9458791262877f2be26c034ab 297 Gene3D G3DSA:3.40.225.10 121 297 7.3E-44 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_10320 16e799a9458791262877f2be26c034ab 297 SUPERFAMILY SSF53639 126 294 1.73E-44 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_10320 16e799a9458791262877f2be26c034ab 297 Gene3D G3DSA:1.10.10.60 15 51 1.2E-6 T 23-10-2018 A3L14_10320 16e799a9458791262877f2be26c034ab 297 SMART SM00530 19 74 1.9E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_10320 16e799a9458791262877f2be26c034ab 297 Pfam PF10120 Thiamine-phosphate synthase 133 291 4.8E-46 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_10320 16e799a9458791262877f2be26c034ab 297 Pfam PF01381 Helix-turn-helix 23 66 1.6E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_10320 16e799a9458791262877f2be26c034ab 297 SUPERFAMILY SSF47413 14 66 7.5E-9 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 SUPERFAMILY SSF63867 331 399 1.02E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Gene3D G3DSA:2.40.340.10 329 400 3.7E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 6.6E-24 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Gene3D G3DSA:3.90.105.10 26 178 2.0E-113 T 23-10-2018 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Gene3D G3DSA:2.170.190.11 49 145 2.0E-113 T 23-10-2018 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 SMART SM00852 184 321 8.0E-37 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 9.4E-19 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 1.4E-42 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 SUPERFAMILY SSF63882 7 180 4.32E-56 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 Gene3D G3DSA:3.40.980.10 179 320 2.0E-113 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 1.1E-31 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_08615 ba6ca5e6b57556c78dcdfef2c37e0280 400 SUPERFAMILY SSF53218 181 325 9.55E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_07565 19b62d17e53e3b0bcb350bed50485417 310 SUPERFAMILY SSF51735 1 303 2.36E-98 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07565 19b62d17e53e3b0bcb350bed50485417 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 1.2E-59 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L14_07565 19b62d17e53e3b0bcb350bed50485417 310 Gene3D G3DSA:3.90.25.10 168 301 1.0E-104 T 23-10-2018 A3L14_07565 19b62d17e53e3b0bcb350bed50485417 310 Gene3D G3DSA:3.40.50.720 8 289 1.0E-104 T 23-10-2018 A3L14_07280 88f3782cbc06e5ebd20bdb37886fdd74 150 SUPERFAMILY SSF52833 2 148 1.03E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_07280 88f3782cbc06e5ebd20bdb37886fdd74 150 Pfam PF00578 AhpC/TSA family 3 127 5.8E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_07280 88f3782cbc06e5ebd20bdb37886fdd74 150 PIRSF PIRSF000239 1 149 1.8E-22 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_07280 88f3782cbc06e5ebd20bdb37886fdd74 150 Gene3D G3DSA:3.40.30.10 1 148 4.1E-44 T 23-10-2018 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 SUPERFAMILY SSF46785 2 61 2.3E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 SMART SM00746 143 179 4.4E-9 T 23-10-2018 IPR011017 TRASH domain A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 8.4E-6 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 8.4E-6 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 9.8E-16 T 23-10-2018 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 SMART SM00344 3 102 7.8E-20 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 Pfam PF08394 Archaeal TRASH domain 143 179 9.1E-21 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 Gene3D G3DSA:1.10.10.10 1 54 1.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_06955 fbb4d7418f1937216165eb7f1dc98cac 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 SUPERFAMILY SSF48179 220 314 2.04E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 Gene3D G3DSA:3.40.50.720 219 447 3.1E-67 T 23-10-2018 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 PIRSF PIRSF500136 10 446 4.2E-145 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 SMART SM00984 335 431 1.3E-29 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 335 431 2.4E-22 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 PIRSF PIRSF000124 20 446 3.7E-76 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 SUPERFAMILY SSF52413 320 441 5.36E-26 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 Gene3D G3DSA:3.40.50.720 9 216 4.8E-60 T 23-10-2018 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 21 198 1.2E-41 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 21 427 1.0E-132 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 SUPERFAMILY SSF51735 21 213 2.91E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00410 51ed7d123dbe42bacbad1daeb890cd04 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 308 3.6E-22 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_01580 5a26be35a6cd7900e2623cd83f7dda6e 211 Pfam PF06510 Protein of unknown function (DUF1102) 39 199 4.2E-46 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 346 356 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 Pfam PF00082 Subtilase family 134 409 8.4E-48 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 2.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 186 2.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 345 361 2.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 135 146 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 SUPERFAMILY SSF54897 46 93 8.5E-8 T 23-10-2018 A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 SUPERFAMILY SSF52743 108 420 2.75E-85 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 Gene3D G3DSA:3.40.50.200 104 422 3.0E-111 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_01520 bf2b53ccf5c6bba8883fa921eb93c6e3 422 Gene3D G3DSA:3.30.70.80 30 94 1.4E-23 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A3L14_06880 0229cc51060d521831e982c012f4e199 110 SMART SM00440 69 108 4.6E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L14_06880 0229cc51060d521831e982c012f4e199 110 PIRSF PIRSF005586 1 110 9.3E-39 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A3L14_06880 0229cc51060d521831e982c012f4e199 110 Gene3D G3DSA:2.20.25.10 55 110 4.0E-29 T 23-10-2018 A3L14_06880 0229cc51060d521831e982c012f4e199 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A3L14_06880 0229cc51060d521831e982c012f4e199 110 SUPERFAMILY SSF57783 47 109 5.1E-24 T 23-10-2018 A3L14_06880 0229cc51060d521831e982c012f4e199 110 Pfam PF01096 Transcription factor S-II (TFIIS) 69 107 1.8E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L14_06880 0229cc51060d521831e982c012f4e199 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 33 1.4E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L14_06880 0229cc51060d521831e982c012f4e199 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 1.8E-38 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A3L14_06880 0229cc51060d521831e982c012f4e199 110 SMART SM00661 2 56 1.0E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L14_06880 0229cc51060d521831e982c012f4e199 110 SUPERFAMILY SSF57783 1 35 2.55E-6 T 23-10-2018 A3L14_06880 0229cc51060d521831e982c012f4e199 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L14_11175 ece793440f344f783ba5f5322778f381 624 SUPERFAMILY SSF53474 352 606 1.14E-56 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_11175 ece793440f344f783ba5f5322778f381 624 SUPERFAMILY SSF82171 24 342 1.26E-22 T 23-10-2018 A3L14_11175 ece793440f344f783ba5f5322778f381 624 Gene3D G3DSA:2.120.10.30 23 134 1.8E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L14_11175 ece793440f344f783ba5f5322778f381 624 Pfam PF00326 Prolyl oligopeptidase family 397 607 6.9E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L14_11175 ece793440f344f783ba5f5322778f381 624 Pfam PF07676 WD40-like Beta Propeller Repeat 61 89 2.7E-4 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L14_11175 ece793440f344f783ba5f5322778f381 624 Gene3D G3DSA:3.40.50.1820 353 623 1.3E-82 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 1.5E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 SUPERFAMILY SSF52540 5 263 4.98E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 8.7E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 SMART SM00382 45 249 3.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 Gene3D G3DSA:3.40.50.300 3 335 1.1E-96 T 23-10-2018 A3L14_00810 ffe2b7dc89fd0ff14f293cf3c86fab76 335 Pfam PF00005 ABC transporter 37 191 3.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 SUPERFAMILY SSF56053 86 177 1.83E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 Gene3D G3DSA:3.90.930.12 6 85 9.3E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 Gene3D G3DSA:3.90.930.12 86 182 9.2E-39 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 PIRSF PIRSF002162 5 182 4.8E-40 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 Pfam PF00347 Ribosomal protein L6 97 171 4.7E-16 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 Pfam PF00347 Ribosomal protein L6 13 85 4.2E-18 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 SUPERFAMILY SSF56053 8 85 8.87E-22 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 5.2E-80 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L14_02560 777ba63a8d3b71a7f30cc31ceca8581c 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.456 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 SUPERFAMILY SSF49344 233 427 1.18E-11 T 23-10-2018 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 SUPERFAMILY SSF49344 930 1088 2.47E-11 T 23-10-2018 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 Gene3D G3DSA:2.60.40.1190 23 229 5.2E-7 T 23-10-2018 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 Gene3D G3DSA:2.60.40.1190 233 431 1.2E-6 T 23-10-2018 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 SUPERFAMILY SSF49344 25 221 1.84E-12 T 23-10-2018 A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 Pfam PF07705 CARDB 444 540 7.5E-20 T 23-10-2018 IPR011635 CARDB domain A3L14_00515 d0972e3964b7a6e036c20843ed3486b7 1137 Gene3D G3DSA:2.60.40.10 432 548 1.7E-33 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Pfam PF01588 Putative tRNA binding domain 650 741 2.2E-32 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Gene3D G3DSA:1.10.730.10 341 581 1.4E-105 T 23-10-2018 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Pfam PF09334 tRNA synthetases class I (M) 4 408 4.8E-159 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 SUPERFAMILY SSF52374 3 395 4.15E-105 T 23-10-2018 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Gene3D G3DSA:1.10.730.10 398 548 1.4E-105 T 23-10-2018 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Pfam PF08264 Anticodon-binding domain of tRNA 430 523 9.0E-12 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 SUPERFAMILY SSF50249 643 743 8.32E-38 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Gene3D G3DSA:2.40.50.140 638 744 1.4E-44 T 23-10-2018 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 SUPERFAMILY SSF47323 398 562 4.3E-45 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Gene3D G3DSA:2.170.220.10 98 252 4.9E-143 T 23-10-2018 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 SUPERFAMILY SSF57770 139 173 5.23E-11 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 2.3E-176 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Gene3D G3DSA:3.40.50.620 5 316 4.9E-143 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 615 744 1.1E-39 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L14_05285 85eed619e360ab1a52b04d04acf57a50 744 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.672 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 4.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 4.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 4.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 4.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 4.0E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 6.3E-62 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 202 4.0E-8 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 Gene3D G3DSA:3.40.50.150 149 439 5.7E-85 T 23-10-2018 A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 Gene3D G3DSA:1.10.940.10 2 148 2.1E-39 T 23-10-2018 IPR035926 NusB-like superfamily A3L14_01740 d39064e40cf3f4b5245ae43a06373883 442 SUPERFAMILY SSF53335 148 439 2.03E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_11350 24a5ffe9c2c63394fc7c25364e2535a9 148 SUPERFAMILY SSF56770 7 138 5.49E-56 T 23-10-2018 A3L14_11350 24a5ffe9c2c63394fc7c25364e2535a9 148 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 5 137 4.1E-44 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11350 24a5ffe9c2c63394fc7c25364e2535a9 148 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 21 131 8.5E-29 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11350 24a5ffe9c2c63394fc7c25364e2535a9 148 Gene3D G3DSA:3.40.50.12280 1 148 3.2E-57 T 23-10-2018 A3L14_09335 2af37f0238ca50eadc9ec674ded5be33 252 Gene3D G3DSA:3.40.50.300 1 244 1.3E-68 T 23-10-2018 A3L14_09335 2af37f0238ca50eadc9ec674ded5be33 252 SUPERFAMILY SSF52540 3 226 6.53E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09335 2af37f0238ca50eadc9ec674ded5be33 252 SMART SM00382 28 220 2.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_09335 2af37f0238ca50eadc9ec674ded5be33 252 Pfam PF00005 ABC transporter 19 162 1.2E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_11510 5108451e9ca6f37c5a319e19db305908 232 Pfam PF00899 ThiF family 10 231 3.1E-58 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L14_11510 5108451e9ca6f37c5a319e19db305908 232 Gene3D G3DSA:3.40.50.720 2 232 1.4E-74 T 23-10-2018 A3L14_11510 5108451e9ca6f37c5a319e19db305908 232 SUPERFAMILY SSF69572 2 230 2.22E-80 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L14_03960 56458ccf2b9da43141d0c92cafde4b28 269 Pfam PF02673 Bacitracin resistance protein BacA 11 251 2.8E-22 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 Gene3D G3DSA:3.90.550.10 1 237 3.4E-79 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 Pfam PF00483 Nucleotidyl transferase 2 231 4.2E-52 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 SUPERFAMILY SSF53448 1 303 1.19E-80 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 Gene3D G3DSA:2.160.10.10 267 361 3.1E-18 T 23-10-2018 A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 SUPERFAMILY SSF51161 200 355 6.79E-25 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 296 329 4.4E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_03545 9f13fcd57e77a8c43bf9c0e35d5f124d 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 258 293 2.5E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 SUPERFAMILY SSF57802 1 53 3.87E-25 T 23-10-2018 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 Gene3D G3DSA:2.20.28.10 2 53 1.0E-29 T 23-10-2018 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 Pfam PF00301 Rubredoxin 3 49 7.5E-26 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 PRINTS PR00163 Rubredoxin signature 33 49 8.3E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 PRINTS PR00163 Rubredoxin signature 3 19 8.3E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L14_07305 855fcd9ff5a500860e38c11c61cb7ffb 53 PIRSF PIRSF000071 1 53 2.0E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 A3L14_02210 f8a90aec1d9a3e9941fb61ec4025d447 131 PIRSF PIRSF019313 1 131 2.5E-30 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A3L14_02210 f8a90aec1d9a3e9941fb61ec4025d447 131 Gene3D G3DSA:3.30.110.150 47 131 4.6E-25 T 23-10-2018 IPR038594 SepF-like superfamily A3L14_02210 f8a90aec1d9a3e9941fb61ec4025d447 131 Pfam PF04472 Cell division protein SepF 57 129 1.0E-13 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.241 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 SUPERFAMILY SSF46785 297 401 6.17E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 SMART SM01074 312 393 8.3E-36 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 196 4.5E-9 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 2.4E-150 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Gene3D G3DSA:3.40.50.300 35 216 2.9E-109 T 23-10-2018 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 2.1E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Gene3D G3DSA:1.10.10.10 304 405 1.4E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 Gene3D G3DSA:1.10.8.60 19 295 2.9E-109 T 23-10-2018 A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 SUPERFAMILY SSF52540 19 291 1.26E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00110 9dd152340e3caf5b26d36755e0a96219 415 SMART SM00382 57 218 5.3E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06340 00dff359e312cab6365c76f897cc488b 148 SUPERFAMILY SSF56784 11 128 4.2E-11 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_06340 00dff359e312cab6365c76f897cc488b 148 Gene3D G3DSA:3.40.50.1000 8 141 7.4E-8 T 23-10-2018 IPR023214 HAD superfamily A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 SMART SM01274 14 145 5.7E-67 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 ProSitePatterns PS00331 Malic enzymes signature. 153 169 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 Pfam PF00390 Malic enzyme, N-terminal domain 23 145 6.8E-24 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 SUPERFAMILY SSF53223 11 155 5.9E-48 T 23-10-2018 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 Pfam PF03949 Malic enzyme, NAD binding domain 158 385 4.2E-18 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 PIRSF PIRSF000106 104 416 5.2E-66 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 PIRSF PIRSF000106 33 111 4.4E-14 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 SUPERFAMILY SSF51735 157 412 4.12E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 Gene3D G3DSA:3.40.50.720 155 426 1.8E-95 T 23-10-2018 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 Gene3D G3DSA:3.40.50.10380 1 154 1.3E-63 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A3L14_10490 c0b22f8ec4c4de8d3a8a5e915536c2e9 426 SMART SM00919 157 386 5.9E-100 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L14_00700 aa303629e3e204fd26e82879ec6d389b 658 Gene3D G3DSA:1.20.1460.20 47 290 2.7E-23 T 23-10-2018 A3L14_00700 aa303629e3e204fd26e82879ec6d389b 658 Gene3D G3DSA:3.30.70.2750 149 224 2.7E-23 T 23-10-2018 A3L14_00700 aa303629e3e204fd26e82879ec6d389b 658 Gene3D G3DSA:3.30.70.2170 7 310 2.7E-23 T 23-10-2018 A3L14_00700 aa303629e3e204fd26e82879ec6d389b 658 Pfam PF01496 V-type ATPase 116kDa subunit family 157 441 3.8E-22 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00700 aa303629e3e204fd26e82879ec6d389b 658 Pfam PF01496 V-type ATPase 116kDa subunit family 554 646 3.9E-12 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 SUPERFAMILY SSF46785 14 64 4.44E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 Gene3D G3DSA:1.10.10.10 5 65 5.1E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 247 1.2E-26 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 Pfam PF03099 Biotin/lipoate A/B protein ligase family 87 204 1.5E-6 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 SUPERFAMILY SSF55681 70 248 9.32E-32 T 23-10-2018 A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 Pfam PF08279 HTH domain 14 62 1.9E-13 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L14_08010 5e03c40a90d097ba75439ca2bc743b3c 257 Gene3D G3DSA:3.30.930.10 74 256 2.2E-32 T 23-10-2018 A3L14_06945 d171e513a4797f65e46c14e61c87ce7c 100 Gene3D G3DSA:3.40.30.10 6 96 3.3E-16 T 23-10-2018 A3L14_06945 d171e513a4797f65e46c14e61c87ce7c 100 Pfam PF00085 Thioredoxin 5 94 3.9E-14 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 A3L14_06945 d171e513a4797f65e46c14e61c87ce7c 100 ProSitePatterns PS00194 Thioredoxin family active site. 17 35 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A3L14_06945 d171e513a4797f65e46c14e61c87ce7c 100 SUPERFAMILY SSF52833 7 94 5.94E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 SUPERFAMILY SSF56327 167 422 2.59E-39 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 Gene3D G3DSA:3.90.1820.20 1 420 3.5E-84 T 23-10-2018 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 SUPERFAMILY SSF51735 1 164 1.83E-27 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 108 128 4.1E-17 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 4.1E-17 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 4.1E-17 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 4.1E-17 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 4.1E-17 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 397 2.0E-32 T 23-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A3L14_09730 afd80e08629cb815dbbd9a0d2e8899f4 435 Pfam PF02056 Family 4 glycosyl hydrolase 3 182 1.7E-22 T 23-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A3L14_05965 0421ab0cb9486e8072fcda746f01e94c 114 SUPERFAMILY SSF51182 11 101 5.94E-23 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_05965 0421ab0cb9486e8072fcda746f01e94c 114 Gene3D G3DSA:2.60.120.10 6 102 1.6E-20 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_05965 0421ab0cb9486e8072fcda746f01e94c 114 Pfam PF07883 Cupin domain 32 100 8.7E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 Gene3D G3DSA:2.70.150.20 123 239 1.2E-40 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 SUPERFAMILY SSF56784 333 637 4.62E-57 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 56 641 2.6E-194 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 468 1.7E-29 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 111 612 1.8E-97 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 SUPERFAMILY SSF81665 72 326 1.96E-13 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 546 4.2E-44 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 99 637 2.6E-116 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 Pfam PF00122 E1-E2 ATPase 135 315 4.6E-53 T 23-10-2018 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 74 639 2.2E-190 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 Gene3D G3DSA:3.40.1110.10 346 464 3.4E-96 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 563 588 9.2E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 379 397 9.2E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 532 548 9.2E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 SUPERFAMILY SSF81653 138 235 6.54E-28 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A3L14_07015 29c4636e3cf6da8924cdc49fa639ee1b 642 Gene3D G3DSA:3.40.50.1000 329 581 3.4E-96 T 23-10-2018 IPR023214 HAD superfamily A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 SUPERFAMILY SSF116726 135 221 3.79E-10 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 SUPERFAMILY SSF51735 1 144 5.05E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 Gene3D G3DSA:3.40.50.720 1 140 1.2E-41 T 23-10-2018 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 Gene3D G3DSA:3.30.70.1450 141 223 1.1E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 Pfam PF02254 TrkA-N domain 3 124 3.3E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 Pfam PF02080 TrkA-C domain 153 221 1.0E-10 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 8.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 8.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 8.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 8.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L14_00690 4da318d820e8049aadfebe14a228fafe 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 8.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 Gene3D G3DSA:3.10.290.10 104 176 4.6E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.41 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 SMART SM01390 5 102 1.9E-6 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 4.8E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 Pfam PF01479 S4 domain 103 148 2.1E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 SUPERFAMILY SSF55174 9 160 1.67E-33 T 23-10-2018 A3L14_02660 7063cbfe465b881031ee1765f0679bcc 180 SMART SM00363 103 165 1.1E-14 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 Gene3D G3DSA:2.40.50.360 119 243 7.9E-113 T 23-10-2018 A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 Gene3D G3DSA:1.10.8.60 354 438 4.5E-26 T 23-10-2018 A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 Gene3D G3DSA:3.40.50.300 17 349 7.9E-113 T 23-10-2018 A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 SUPERFAMILY SSF50249 126 207 1.56E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 Pfam PF06068 TIP49 C-terminus 14 403 2.4E-161 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 SUPERFAMILY SSF52540 37 424 2.26E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04690 393c2d6749c6202621cd71eb1b58646c 440 SMART SM00382 62 353 9.3E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 126 138 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 SUPERFAMILY SSF56112 2 190 2.29E-28 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 Gene3D G3DSA:1.10.510.10 98 217 2.4E-33 T 23-10-2018 A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 Gene3D G3DSA:3.30.200.20 22 90 6.7E-27 T 23-10-2018 A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 SMART SM00220 25 221 3.0E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 Pfam PF01163 RIO1 family 45 149 3.4E-14 T 23-10-2018 A3L14_06245 819a8656bccccbb3de7b7490f5329b3d 222 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 215 1.3E-72 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 Gene3D G3DSA:3.30.300.10 30 154 4.8E-171 T 23-10-2018 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 Gene3D G3DSA:3.30.300.280 16 398 4.8E-171 T 23-10-2018 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.152 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 Gene3D G3DSA:3.30.300.340 18 286 4.8E-171 T 23-10-2018 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 2.9E-179 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L14_05185 cce9566923ef69a3d8a527d92897e5c2 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 SUPERFAMILY SSF52540 4 248 2.6E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 Gene3D G3DSA:3.40.50.300 1 173 2.9E-32 T 23-10-2018 A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 Pfam PF01637 ATPase domain predominantly from Archaea 6 208 6.2E-27 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 Pfam PF09339 IclR helix-turn-helix domain 249 291 1.3E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 SUPERFAMILY SSF46785 247 327 3.93E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07805 27639a7a82f8729034c49377a6c49aba 469 Pfam PF03008 Archaea bacterial proteins of unknown function 318 414 2.1E-27 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_04340 2932a08a87e122e0262d042de351d4f4 408 SUPERFAMILY SSF53756 5 387 2.94E-74 T 23-10-2018 A3L14_04340 2932a08a87e122e0262d042de351d4f4 408 Gene3D G3DSA:3.40.50.2000 183 372 1.6E-71 T 23-10-2018 A3L14_04340 2932a08a87e122e0262d042de351d4f4 408 Pfam PF00534 Glycosyl transferases group 1 196 365 1.8E-21 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L14_04340 2932a08a87e122e0262d042de351d4f4 408 Gene3D G3DSA:3.40.50.2000 8 373 1.6E-71 T 23-10-2018 A3L14_04340 2932a08a87e122e0262d042de351d4f4 408 Pfam PF13439 Glycosyltransferase Family 4 17 185 4.4E-29 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 6.8E-75 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 37.954 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Gene3D G3DSA:1.20.120.140 6 300 9.5E-122 T 23-10-2018 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Pfam PF02978 Signal peptide binding domain 327 425 1.5E-34 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.1E-20 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Gene3D G3DSA:3.40.50.300 91 284 9.5E-122 T 23-10-2018 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SUPERFAMILY SSF52540 96 297 1.42E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SMART SM00382 99 300 4.1E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SMART SM00963 2 87 1.2E-23 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SUPERFAMILY SSF47364 1 94 2.88E-23 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 Gene3D G3DSA:1.10.260.30 301 430 6.6E-45 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SMART SM00962 100 295 1.1E-98 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_02780 c0e7636587b0d4dfa671b4d9290a1f9b 448 SUPERFAMILY SSF47446 297 429 2.35E-43 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_04420 75b06c9d0f24057a739da83dcf577fd5 313 SUPERFAMILY SSF161098 79 301 1.44E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04420 75b06c9d0f24057a739da83dcf577fd5 313 Gene3D G3DSA:1.10.3720.10 57 311 4.0E-58 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04420 75b06c9d0f24057a739da83dcf577fd5 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 297 3.7E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 SUPERFAMILY SSF54570 34 117 1.57E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 2.6E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.943 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 Gene3D G3DSA:3.30.860.20 2 133 2.9E-54 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 Pfam PF00203 Ribosomal protein S19 35 116 2.1E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 4.1E-27 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 PIRSF PIRSF002144 1 133 8.2E-41 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02495 2dc9760c9ad3fff6cbc28b6f171c407a 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 5.3E-66 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 26.438 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 SUPERFAMILY SSF48140 1 141 6.02E-59 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 SMART SM01416 1 144 3.9E-91 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 Gene3D G3DSA:1.10.1200.240 56 147 3.8E-31 T 23-10-2018 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 Gene3D G3DSA:1.10.1650.10 1 54 5.1E-26 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 Pfam PF01280 Ribosomal protein L19e 2 143 3.0E-60 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02570 063b06b3a2a48667abe9e3646e6365f6 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 Pfam PF01300 Telomere recombination 22 196 1.1E-60 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 SUPERFAMILY SSF55821 10 209 3.97E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 Gene3D G3DSA:3.90.870.10 3 212 5.1E-86 T 23-10-2018 A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 5.4E-67 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 Gene3D G3DSA:3.40.50.11030 235 339 1.0E-39 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 PIRSF PIRSF004930 1 338 2.0E-131 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A3L14_08585 7b751c38f52d7eb4412046eda087f2d5 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 333 3.3E-28 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 SUPERFAMILY SSF46785 3 150 8.53E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.6 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 Gene3D G3DSA:1.10.10.2700 1 150 1.1E-65 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 2.0E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 Pfam PF01090 Ribosomal protein S19e 3 138 9.1E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08670 961a78c5631c5ea90607a060f08e7d3e 150 SMART SM01413 3 139 1.6E-89 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 Gene3D G3DSA:3.40.50.300 4 202 3.0E-45 T 23-10-2018 A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 Pfam PF00271 Helicase conserved C-terminal domain 240 336 7.1E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 Pfam PF08494 DEAD/H associated 583 747 2.1E-16 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 SMART SM00490 259 341 5.0E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 SMART SM00487 12 210 2.9E-35 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 Pfam PF00270 DEAD/DEAH box helicase 18 182 2.7E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 SUPERFAMILY SSF52540 28 350 5.89E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07715 2c17d1dd1b61910b95075e0fdbd02e54 923 Gene3D G3DSA:3.40.50.300 217 373 1.5E-29 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 4.2E-13 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 9.8E-34 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:1.10.10.1010 619 764 7.5E-231 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SUPERFAMILY SSF55608 848 940 3.87E-18 T 23-10-2018 IPR027434 Homing endonuclease A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 65 492 6.8E-94 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 1027 1282 3.8E-99 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00379 Intein signature 1003 1020 6.4E-23 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00379 Intein signature 578 591 6.4E-23 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00379 Intein signature 865 877 6.4E-23 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00379 Intein signature 892 907 6.4E-23 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00379 Intein signature 769 781 6.4E-23 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SUPERFAMILY SSF53098 1 347 3.75E-88 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.30.1490.210 934 986 7.5E-231 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SMART SM00306 490 615 4.6E-27 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 1073 1081 1.1E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 483 495 1.1E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 400 413 1.1E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF14890 Intein splicing domain 508 1028 8.4E-54 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 507 590 1.7E-8 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:1.10.287.690 447 493 2.0E-17 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SMART SM00305 986 1034 7.2E-13 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF14528 LAGLIDADG-like domain 865 923 8.8E-7 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SUPERFAMILY SSF56672 1027 1295 1.06E-79 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF00136 DNA polymerase family B 352 493 1.8E-29 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Pfam PF00136 DNA polymerase family B 1028 1284 1.1E-41 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 ProSitePatterns PS00116 DNA polymerase family B signature. 1075 1083 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.10.28.10 765 933 7.5E-231 T 23-10-2018 IPR027434 Homing endonuclease A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.30.342.10 3 366 1.3E-171 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:2.170.16.10 506 1026 7.5E-231 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SUPERFAMILY SSF56672 349 493 3.5E-43 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SMART SM00486 133 540 1.8E-102 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 SUPERFAMILY SSF51294 492 1029 2.35E-39 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1005 1029 8.5E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.90.1600.10 1027 1143 2.8E-36 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.30.420.10 131 347 1.3E-171 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:3.90.1600.20 378 444 3.3E-13 T 23-10-2018 A3L14_01995 809be4a75114b6068a6e8749afce759b 1311 Gene3D G3DSA:1.10.132.60 1144 1310 8.7E-62 T 23-10-2018 A3L14_08085 1a60657a864545994e3d1e49099ce9f7 677 Pfam PF00149 Calcineurin-like phosphoesterase 128 368 2.6E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_08085 1a60657a864545994e3d1e49099ce9f7 677 Gene3D G3DSA:3.60.21.10 182 375 1.1E-16 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_08085 1a60657a864545994e3d1e49099ce9f7 677 SUPERFAMILY SSF56300 127 412 2.32E-28 T 23-10-2018 A3L14_08085 1a60657a864545994e3d1e49099ce9f7 677 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 657 676 6.0E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 Gene3D G3DSA:3.40.50.1390 64 160 2.0E-27 T 23-10-2018 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 SUPERFAMILY SSF46955 6 55 3.2E-11 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 SUPERFAMILY SSF53041 63 189 3.14E-22 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 Pfam PF00239 Resolvase, N terminal domain 63 194 1.8E-24 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 SMART SM00857 63 184 8.9E-24 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 54 4.3E-10 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 Gene3D G3DSA:1.10.1660.10 8 63 4.9E-13 T 23-10-2018 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 Pfam PF12728 Helix-turn-helix domain 7 54 1.6E-12 T 23-10-2018 A3L14_08145 df2dbe20c4c0dcdaddfb3b845694360c 209 ProSitePatterns PS00397 Site-specific recombinases active site. 66 74 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Gene3D G3DSA:3.90.740.10 170 337 1.4E-240 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_06000 665dd5150641bfb391277033137fea4c 890 SUPERFAMILY SSF50677 187 335 2.49E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Gene3D G3DSA:1.10.730.10 2 752 1.4E-240 T 23-10-2018 A3L14_06000 665dd5150641bfb391277033137fea4c 890 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 868 8.0E-270 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Gene3D G3DSA:3.40.50.620 22 537 1.4E-240 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_06000 665dd5150641bfb391277033137fea4c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 488 506 1.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 1.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 1.5E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Pfam PF08264 Anticodon-binding domain of tRNA 616 764 6.9E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L14_06000 665dd5150641bfb391277033137fea4c 890 SUPERFAMILY SSF52374 3 581 3.47E-127 T 23-10-2018 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 795 28.886 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A3L14_06000 665dd5150641bfb391277033137fea4c 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 572 3.9E-142 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_06000 665dd5150641bfb391277033137fea4c 890 SUPERFAMILY SSF47323 588 827 4.49E-59 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_06000 665dd5150641bfb391277033137fea4c 890 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 6.9E-64 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 SUPERFAMILY SSF56091 219 422 3.6E-56 T 23-10-2018 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Gene3D G3DSA:3.30.470.30 221 422 3.3E-73 T 23-10-2018 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Pfam PF04675 DNA ligase N terminus 3 176 1.7E-38 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Gene3D G3DSA:1.10.3260.10 1 220 2.1E-84 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 SUPERFAMILY SSF117018 2 242 9.02E-71 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 8.9E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 SUPERFAMILY SSF50249 425 552 6.28E-40 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Gene3D G3DSA:2.40.50.140 423 559 4.7E-51 T 23-10-2018 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 9.2E-163 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A3L14_10840 ade8d1aa274bda599bf74c48fdf0e992 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.62 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A3L14_01870 a78570afef6e83a3bc4bbfcdd980881c 267 SUPERFAMILY SSF50249 34 131 5.14E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_01870 a78570afef6e83a3bc4bbfcdd980881c 267 Gene3D G3DSA:2.40.50.140 9 141 9.3E-13 T 23-10-2018 A3L14_01870 a78570afef6e83a3bc4bbfcdd980881c 267 Pfam PF01336 OB-fold nucleic acid binding domain 43 114 4.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 1.2E-94 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 Gene3D G3DSA:3.30.70.150 1 136 4.0E-45 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.245 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 3.9E-45 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 SUPERFAMILY SSF54966 4 137 1.57E-38 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 4.5E-218 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 Gene3D G3DSA:3.20.20.110 137 438 5.4E-125 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_09170 630a9e7b00a6f62a810b9fc92fb4af74 444 SUPERFAMILY SSF51649 136 441 1.83E-106 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L14_08485 4934b1ceec713c0907e4a8153fa20489 118 SUPERFAMILY SSF88723 4 111 5.33E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08485 4934b1ceec713c0907e4a8153fa20489 118 Gene3D G3DSA:3.40.50.1010 3 115 2.6E-5 T 23-10-2018 A3L14_08485 4934b1ceec713c0907e4a8153fa20489 118 Pfam PF10130 PIN domain 6 110 1.3E-18 T 23-10-2018 IPR002716 PIN domain A3L14_07410 43a443f4b48874e325dd2f6ecb1cda70 174 Pfam PF02915 Rubrerythrin 7 147 7.3E-14 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_07410 43a443f4b48874e325dd2f6ecb1cda70 174 Gene3D G3DSA:1.20.1260.10 1 152 6.0E-32 T 23-10-2018 IPR012347 Ferritin-like A3L14_07410 43a443f4b48874e325dd2f6ecb1cda70 174 SUPERFAMILY SSF47240 4 153 1.28E-21 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_09940 d444f929163ccda1c766441a3d7b0a40 262 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 241 3.6E-76 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L14_09940 d444f929163ccda1c766441a3d7b0a40 262 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 70 251 2.0E-91 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L14_09940 d444f929163ccda1c766441a3d7b0a40 262 Gene3D G3DSA:3.40.50.12640 1 261 1.9E-122 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A3L14_09940 d444f929163ccda1c766441a3d7b0a40 262 PIRSF PIRSF004853 1 253 1.3E-114 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 Gene3D G3DSA:3.40.50.360 259 405 5.2E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 PIRSF PIRSF005243 4 408 2.5E-112 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 5.2E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 SUPERFAMILY SSF56281 3 255 2.49E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 SUPERFAMILY SSF52218 262 406 4.57E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 Gene3D G3DSA:3.60.15.10 1 258 5.6E-91 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_07285 d76fd35e215bfe4d645a6698f63481d4 409 SMART SM00849 39 209 6.3E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_05790 86e391d2a8d97224f812764fadeb36d6 201 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 199 36.275 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L14_05790 86e391d2a8d97224f812764fadeb36d6 201 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 8.5E-49 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L14_05790 86e391d2a8d97224f812764fadeb36d6 201 SUPERFAMILY SSF75217 1 198 2.35E-67 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_05790 86e391d2a8d97224f812764fadeb36d6 201 Gene3D G3DSA:3.40.1280.10 1 200 9.6E-69 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 SUPERFAMILY SSF52402 151 276 2.76E-20 T 23-10-2018 A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 Gene3D G3DSA:3.40.50.620 1 142 2.0E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 PRINTS PR01438 Universal stress protein signature 254 276 2.6E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 PRINTS PR01438 Universal stress protein signature 236 248 2.6E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 PRINTS PR01438 Universal stress protein signature 2 20 2.6E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 Pfam PF00582 Universal stress protein family 1 133 1.4E-20 T 23-10-2018 IPR006016 UspA A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 Pfam PF00582 Universal stress protein family 194 276 1.8E-16 T 23-10-2018 IPR006016 UspA A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 Gene3D G3DSA:3.40.50.620 148 278 1.3E-23 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_10675 b02dcfc8339e30742259d69147aa9ac1 278 SUPERFAMILY SSF52402 1 133 8.37E-27 T 23-10-2018 A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 SUPERFAMILY SSF53335 2 252 4.85E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 PIRSF PIRSF017269 1 253 1.0E-79 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 234 5.8E-28 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 2 46 9.6E-9 T 23-10-2018 A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 Gene3D G3DSA:3.40.50.150 63 253 9.0E-69 T 23-10-2018 A3L14_09385 4880aa89f1cbe890723ad2f4fc7afed7 253 Gene3D G3DSA:3.10.330.20 1 61 4.2E-24 T 23-10-2018 A3L14_04655 7fe180201d52d5cde8ff6547714158dd 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.941 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_04655 7fe180201d52d5cde8ff6547714158dd 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 7.4E-11 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_04655 7fe180201d52d5cde8ff6547714158dd 49 SUPERFAMILY SSF63393 4 48 7.32E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L14_04655 7fe180201d52d5cde8ff6547714158dd 49 SMART SM00659 4 49 1.2E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_04655 7fe180201d52d5cde8ff6547714158dd 49 Gene3D G3DSA:2.20.28.30 1 49 1.3E-23 T 23-10-2018 A3L14_08780 b82271dd7f62d75d79edc9753f71e1b6 249 SMART SM00849 37 215 2.5E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_08780 b82271dd7f62d75d79edc9753f71e1b6 249 Pfam PF12706 Beta-lactamase superfamily domain 64 216 5.6E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_08780 b82271dd7f62d75d79edc9753f71e1b6 249 Gene3D G3DSA:3.60.15.10 2 249 6.7E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_08780 b82271dd7f62d75d79edc9753f71e1b6 249 SUPERFAMILY SSF56281 3 247 1.0E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 210 229 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 116 136 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 664 681 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 411 425 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 258 277 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00943 Copper-transporting ATPase signature 721 735 4.1E-15 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00942 Copper-transporting ATPase 1 signature 208 233 6.4E-9 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00942 Copper-transporting ATPase 1 signature 2 27 6.4E-9 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00942 Copper-transporting ATPase 1 signature 95 116 6.4E-9 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Gene3D G3DSA:2.70.150.20 281 393 1.5E-45 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 66 1.7E-14 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 135 8.9E-13 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Gene3D G3DSA:3.40.1110.10 500 619 4.0E-102 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 252 769 1.6E-128 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 SUPERFAMILY SSF81653 292 388 4.71E-31 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Pfam PF00122 E1-E2 ATPase 289 468 8.4E-60 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Gene3D G3DSA:3.40.50.1000 470 739 4.0E-102 T 23-10-2018 IPR023214 HAD superfamily A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 ProSitePatterns PS01047 Heavy-metal-associated domain. 77 106 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 SUPERFAMILY SSF55008 3 67 3.53E-20 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 623 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 644 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 503 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 687 706 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 710 722 3.4E-26 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Gene3D G3DSA:3.30.70.100 2 70 1.6E-21 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 SUPERFAMILY SSF81665 253 481 4.84E-14 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Pfam PF00702 haloacid dehalogenase-like hydrolase 487 701 2.3E-47 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 491 497 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 797 4.5E-188 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 261 765 2.7E-107 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 SUPERFAMILY SSF55008 73 138 4.58E-22 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Pfam PF00403 Heavy-metal-associated domain 6 64 1.1E-14 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Pfam PF00403 Heavy-metal-associated domain 74 135 1.6E-18 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 Gene3D G3DSA:3.30.70.100 71 136 1.1E-23 T 23-10-2018 A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 SUPERFAMILY SSF56784 487 794 1.04E-62 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_06950 62d47d21d17b30aa0298c2f83e69820b 801 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 225 796 1.3E-203 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 4.7E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.7E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.7E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 Pfam PF02421 Ferrous iron transport protein B 4 159 3.7E-64 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 625 2.4E-187 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 Pfam PF07670 Nucleoside recognition 353 447 1.8E-13 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 Pfam PF07670 Nucleoside recognition 514 628 4.0E-27 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 158 9.4E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 SUPERFAMILY SSF52540 1 166 4.77E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 2.1E-19 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A3L14_05915 c9ecbad73f7af2ec576337467f8169ad 658 Gene3D G3DSA:3.40.50.300 2 189 2.6E-48 T 23-10-2018 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 Gene3D G3DSA:3.30.930.10 107 438 1.0E-121 T 23-10-2018 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 Gene3D G3DSA:2.40.50.140 1 105 4.5E-27 T 23-10-2018 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 2.3E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 3.9E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 3.9E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 3.9E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 3.9E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 5.4E-184 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 3.6E-94 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.685 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 SUPERFAMILY SSF55681 96 437 2.77E-99 T 23-10-2018 A3L14_03865 5c0dd3bc6566889b70cdb406ae5f6865 438 SUPERFAMILY SSF50249 1 102 1.47E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Gene3D G3DSA:2.30.130.70 83 162 3.4E-15 T 23-10-2018 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Gene3D G3DSA:3.40.50.150 188 382 1.3E-61 T 23-10-2018 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 173 187 1.4E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 202 212 1.4E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 268 280 1.4E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 381 1.4E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 315 331 1.4E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 SUPERFAMILY SSF88697 88 159 1.38E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 SMART SM00359 89 163 2.4E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Gene3D G3DSA:3.30.70.3130 2 82 1.1E-12 T 23-10-2018 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 167 381 2.7E-63 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 7 77 1.9E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 90 158 4.5E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 SUPERFAMILY SSF53335 4 382 2.56E-56 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Pfam PF01472 PUA domain 92 158 1.9E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_00035 ffade2dc6ef0aaba4443a58aae08a275 382 Pfam PF01189 16S rRNA methyltransferase RsmB/F 191 380 2.9E-56 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L14_09725 2ee448d3ee5cada75591686e63ea1a05 265 Pfam PF02585 GlcNAc-PI de-N-acetylase 42 166 3.7E-27 T 23-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A3L14_09725 2ee448d3ee5cada75591686e63ea1a05 265 Gene3D G3DSA:3.40.50.10320 15 265 3.4E-83 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L14_09725 2ee448d3ee5cada75591686e63ea1a05 265 SUPERFAMILY SSF102588 39 253 2.35E-54 T 23-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 Gene3D G3DSA:3.40.50.620 1 134 1.9E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 216 1.1E-87 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 Pfam PF01902 Diphthamide synthase 1 220 2.6E-86 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 6.7E-85 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 PIRSF PIRSF039123 1 224 2.1E-79 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 221 2.2E-91 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 SUPERFAMILY SSF52402 1 219 1.37E-73 T 23-10-2018 A3L14_09235 09025cfb5b5f92af46a3975c1b344a31 224 Gene3D G3DSA:3.90.1490.10 137 224 1.8E-31 T 23-10-2018 A3L14_05820 6a505ed3626f37e229026ccba5abdb77 76 SMART SM00651 7 72 5.7E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L14_05820 6a505ed3626f37e229026ccba5abdb77 76 SUPERFAMILY SSF50182 5 74 1.99E-17 T 23-10-2018 IPR010920 LSM domain superfamily A3L14_05820 6a505ed3626f37e229026ccba5abdb77 76 Gene3D G3DSA:2.30.30.100 1 74 7.7E-23 T 23-10-2018 A3L14_05820 6a505ed3626f37e229026ccba5abdb77 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.291 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A3L14_05820 6a505ed3626f37e229026ccba5abdb77 76 Pfam PF01423 LSM domain 9 72 2.0E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 35 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Gene3D G3DSA:3.40.1110.10 409 520 8.6E-84 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Pfam PF00403 Heavy-metal-associated domain 6 57 9.4E-9 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 247 261 3.4E-22 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 546 3.4E-22 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 626 3.4E-22 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 3.4E-22 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 398 412 3.4E-22 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 SUPERFAMILY SSF55008 3 57 2.09E-9 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 668 3.1E-82 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 SUPERFAMILY SSF81665 148 690 2.22E-15 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 148 695 1.6E-165 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 148 692 1.8E-178 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Gene3D G3DSA:2.70.150.20 190 302 1.2E-34 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 SUPERFAMILY SSF81653 201 297 7.19E-26 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Pfam PF00702 haloacid dehalogenase-like hydrolase 396 604 3.4E-39 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Pfam PF00122 E1-E2 ATPase 198 378 2.4E-55 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00941 Cadmium-transporting ATPase signature 5 14 5.3E-8 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00941 Cadmium-transporting ATPase signature 110 127 5.3E-8 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00941 Cadmium-transporting ATPase signature 263 279 5.3E-8 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00941 Cadmium-transporting ATPase signature 182 202 5.3E-8 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 PRINTS PR00941 Cadmium-transporting ATPase signature 282 296 5.3E-8 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 SUPERFAMILY SSF56784 396 691 4.02E-59 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Gene3D G3DSA:3.30.70.100 2 80 2.4E-9 T 23-10-2018 A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 Gene3D G3DSA:3.40.50.1000 379 643 8.6E-84 T 23-10-2018 IPR023214 HAD superfamily A3L14_07105 0fdd1d5e44ae18170efc581738756f94 695 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 400 406 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 269 293 1.2E-5 T 23-10-2018 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 1.2E-5 T 23-10-2018 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 247 259 1.2E-5 T 23-10-2018 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 250 256 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 327 5.8E-97 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 SMART SM00981 56 141 8.2E-5 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 SUPERFAMILY SSF53335 152 311 6.98E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 Pfam PF01170 Putative RNA methylase family UPF0020 156 305 3.9E-25 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 Gene3D G3DSA:3.40.50.150 153 330 3.4E-33 T 23-10-2018 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 Pfam PF02926 THUMP domain 31 133 1.8E-9 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_07470 8af39fbdeabd84ac64adf5d045655f1e 330 SUPERFAMILY SSF143437 27 132 2.09E-8 T 23-10-2018 A3L14_02255 3c9e13cd132d25ebfdd4049bb227fc31 123 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 82 3.1E-12 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L14_02255 3c9e13cd132d25ebfdd4049bb227fc31 123 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 81 3.9E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L14_02255 3c9e13cd132d25ebfdd4049bb227fc31 123 PIRSF PIRSF018867 1 120 3.4E-29 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 SMART SM01374 20 141 1.6E-55 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 3.4E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 Gene3D G3DSA:2.40.150.20 1 140 3.4E-48 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 SUPERFAMILY SSF50193 16 141 1.44E-43 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.8E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L14_02530 80526e485c03baaa57b05262b3e6676e 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.467 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L14_01965 881196d4349595c0575d2768d6613ce6 204 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 2.5E-59 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A3L14_01965 881196d4349595c0575d2768d6613ce6 204 SUPERFAMILY SSF143447 3 202 6.8E-70 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A3L14_01965 881196d4349595c0575d2768d6613ce6 204 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 3 196 5.6E-70 T 23-10-2018 IPR023473 AMMECR1 A3L14_01965 881196d4349595c0575d2768d6613ce6 204 Gene3D G3DSA:3.30.700.20 9 192 4.7E-74 T 23-10-2018 IPR027485 AMMECR1, N-terminal A3L14_01965 881196d4349595c0575d2768d6613ce6 204 Gene3D G3DSA:3.30.1490.150 117 190 4.7E-74 T 23-10-2018 A3L14_01965 881196d4349595c0575d2768d6613ce6 204 Hamap MF_00645 Protein . 5 188 41.659 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A3L14_01965 881196d4349595c0575d2768d6613ce6 204 Pfam PF01871 AMMECR1 13 190 3.5E-54 T 23-10-2018 IPR002733 AMMECR1 domain A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 Pfam PF01472 PUA domain 3 73 2.8E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 SUPERFAMILY SSF88697 1 70 2.73E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 SUPERFAMILY SSF53335 78 389 7.07E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 Gene3D G3DSA:3.40.50.150 179 396 1.9E-71 T 23-10-2018 A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 SMART SM00359 2 87 7.1E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 Gene3D G3DSA:2.30.130.10 1 71 2.2E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 334 2.3E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A3L14_00890 f4db0b442bb3c308404894b1688d26e0 396 Gene3D G3DSA:3.30.750.80 72 178 8.0E-37 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 1.3E-106 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:1.20.120.1280 1 121 2.3E-30 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 SMART SM00663 211 515 6.8E-206 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:3.30.1490.180 354 418 9.5E-81 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 SUPERFAMILY SSF64484 4 887 0.0 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:1.10.132.30 672 813 7.8E-45 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:2.40.40.20 311 482 9.5E-81 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:2.20.25.410 850 900 7.9E-22 T 23-10-2018 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 2.1E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 4.4E-74 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 1.6E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 8.1E-37 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03415 70d8e2a2de0360613204279617759e60 905 Gene3D G3DSA:1.10.274.100 491 671 2.3E-63 T 23-10-2018 A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 PIRSF PIRSF005590 1 180 1.8E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.84 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 1.1E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 Gene3D G3DSA:3.90.1170.10 1 180 1.2E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02440 e6ce4f03b400876c61e89ca49eaba0ef 182 SUPERFAMILY SSF54686 4 168 6.02E-56 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 Pfam PF07687 Peptidase dimerisation domain 181 272 3.1E-9 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 Pfam PF01546 Peptidase family M20/M25/M40 68 375 6.2E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 PIRSF PIRSF005962 1 381 3.6E-134 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 Gene3D G3DSA:3.30.70.360 176 290 2.0E-145 T 23-10-2018 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 SUPERFAMILY SSF55031 177 285 9.03E-31 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 SUPERFAMILY SSF53187 5 380 4.29E-89 T 23-10-2018 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 Gene3D G3DSA:3.40.630.10 14 365 2.0E-145 T 23-10-2018 A3L14_03905 b3a58b20d07e93abed52cfa48a294b9e 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 6.0E-123 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L14_03375 1c50b9a6ae46cbe5c8bade6de7bd013f 373 Gene3D G3DSA:3.40.720.10 1 371 3.4E-57 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L14_03375 1c50b9a6ae46cbe5c8bade6de7bd013f 373 SUPERFAMILY SSF53649 1 359 5.09E-76 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_03375 1c50b9a6ae46cbe5c8bade6de7bd013f 373 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 1.1E-50 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L14_06200 40b6a2298fdb8d99c44d802224c30a1d 210 Gene3D G3DSA:3.40.50.850 14 205 4.9E-45 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L14_06200 40b6a2298fdb8d99c44d802224c30a1d 210 Pfam PF00857 Isochorismatase family 34 196 2.7E-37 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L14_06200 40b6a2298fdb8d99c44d802224c30a1d 210 SUPERFAMILY SSF52499 29 207 5.1E-46 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 SUPERFAMILY SSF161098 23 313 2.34E-42 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 Gene3D G3DSA:1.10.3720.10 331 600 8.9E-36 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 Gene3D G3DSA:1.10.3720.10 19 320 8.1E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 306 1.1E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 418 602 8.3E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_08070 e777fe425ee775ba3f2863a3ab67ff06 613 SUPERFAMILY SSF161098 334 606 5.05E-40 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 Pfam PF00571 CBS domain 122 176 6.4E-14 T 23-10-2018 IPR000644 CBS domain A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 Pfam PF00571 CBS domain 47 97 3.5E-9 T 23-10-2018 IPR000644 CBS domain A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 SUPERFAMILY SSF54631 32 176 1.88E-28 T 23-10-2018 A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 Gene3D G3DSA:3.10.580.10 99 179 3.8E-16 T 23-10-2018 A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 Gene3D G3DSA:3.10.580.10 8 98 1.2E-10 T 23-10-2018 A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 SMART SM00116 51 98 0.0059 T 23-10-2018 IPR000644 CBS domain A3L14_00555 e885585aaff2cd337c3d2cbf0fb553e8 181 SMART SM00116 129 177 1.6E-10 T 23-10-2018 IPR000644 CBS domain A3L14_06840 d19ac6acbb8ef2b318f1b49ec4a8a982 251 Gene3D G3DSA:3.40.50.1220 12 242 8.9E-91 T 23-10-2018 A3L14_06840 d19ac6acbb8ef2b318f1b49ec4a8a982 251 SUPERFAMILY SSF52467 2 246 2.86E-90 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L14_06840 d19ac6acbb8ef2b318f1b49ec4a8a982 251 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 60.589 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A3L14_06840 d19ac6acbb8ef2b318f1b49ec4a8a982 251 Pfam PF02146 Sir2 family 20 198 8.1E-59 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A3L14_06840 d19ac6acbb8ef2b318f1b49ec4a8a982 251 Gene3D G3DSA:3.30.1600.10 29 168 8.9E-91 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A3L14_10845 800ce0cffdd967a59a9519f8743cf80e 300 SUPERFAMILY SSF54211 3 156 2.81E-11 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_10845 800ce0cffdd967a59a9519f8743cf80e 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 1.5E-6 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L14_10845 800ce0cffdd967a59a9519f8743cf80e 300 PIRSF PIRSF016896 1 295 1.3E-87 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A3L14_00835 ab4f35d7b2fbdfb8367dea123ecc9cb5 135 Pfam PF01886 Protein of unknown function DUF61 6 132 2.0E-35 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L14_00835 ab4f35d7b2fbdfb8367dea123ecc9cb5 135 PIRSF PIRSF005264 1 135 3.0E-43 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L14_00835 ab4f35d7b2fbdfb8367dea123ecc9cb5 135 Hamap MF_00585 UPF0216 protein . 4 135 26.607 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L14_00835 ab4f35d7b2fbdfb8367dea123ecc9cb5 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 4.0E-39 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 2.8E-29 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 Gene3D G3DSA:3.40.1350.10 79 171 2.1E-31 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 32.947 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 PIRSF PIRSF005285 8 171 1.6E-63 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 7 69 1.1E-20 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 Gene3D G3DSA:3.40.1170.20 8 73 1.8E-17 T 23-10-2018 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 9 169 5.6E-36 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 SUPERFAMILY SSF55267 6 77 4.12E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L14_10190 fa7a253aa825c49ba6e78d82b0d50d34 171 SUPERFAMILY SSF53032 79 169 1.96E-28 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L14_07695 54a66e9be92e2c80976791783cda356b 479 Pfam PF07690 Major Facilitator Superfamily 9 402 2.2E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_07695 54a66e9be92e2c80976791783cda356b 479 Gene3D G3DSA:1.20.1720.10 1 198 5.2E-46 T 23-10-2018 A3L14_07695 54a66e9be92e2c80976791783cda356b 479 Gene3D G3DSA:1.20.1250.20 246 460 8.7E-14 T 23-10-2018 A3L14_07695 54a66e9be92e2c80976791783cda356b 479 SUPERFAMILY SSF103473 3 469 2.49E-67 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_07365 1c4b22b4cd5da47f01b359965ce5d4fe 175 Pfam PF00583 Acetyltransferase (GNAT) family 46 160 2.8E-14 T 23-10-2018 IPR000182 GNAT domain A3L14_07365 1c4b22b4cd5da47f01b359965ce5d4fe 175 SUPERFAMILY SSF55729 14 169 3.09E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_07365 1c4b22b4cd5da47f01b359965ce5d4fe 175 Gene3D G3DSA:3.30.1990.20 145 175 7.2E-10 T 23-10-2018 A3L14_07365 1c4b22b4cd5da47f01b359965ce5d4fe 175 Gene3D G3DSA:3.40.630.30 2 144 9.8E-61 T 23-10-2018 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 1.3E-38 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.551 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 203 3.2E-51 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 SUPERFAMILY SSF51366 2 210 4.12E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 SMART SM00934 3 203 3.2E-62 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09255 d6743715522cbd5002812b7df68f5dc6 211 Gene3D G3DSA:3.20.20.70 1 210 3.1E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 Pfam PF02254 TrkA-N domain 3 106 8.5E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 Pfam PF01368 DHH family 165 315 1.2E-9 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 SUPERFAMILY SSF51735 1 138 1.23E-18 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 Gene3D G3DSA:3.90.1640.10 163 366 9.3E-27 T 23-10-2018 A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 SUPERFAMILY SSF64182 162 453 8.11E-56 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 Pfam PF02272 DHHA1 domain 355 460 1.9E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L14_05155 c40a2b4d67ac8ba8f43b690ebe1da2dd 487 Gene3D G3DSA:3.40.50.720 1 140 8.0E-20 T 23-10-2018 A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 10 198 6.5E-52 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 3.7E-12 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 SUPERFAMILY SSF54980 136 198 2.73E-9 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 Gene3D G3DSA:3.30.230.30 2 131 3.4E-47 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 SUPERFAMILY SSF54211 4 130 1.21E-41 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_06345 1476c54c98d446ea31f7586eae0325a4 209 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 1.3E-32 T 23-10-2018 IPR001498 Impact, N-terminal A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 Pfam PF13353 4Fe-4S single cluster domain 21 124 4.6E-6 T 23-10-2018 A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 263 343 5.5E-12 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 Pfam PF04055 Radical SAM superfamily 19 175 4.4E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 SUPERFAMILY SSF102114 8 329 1.96E-50 T 23-10-2018 A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 PIRSF PIRSF037420 10 207 1.3E-29 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 PIRSF PIRSF037420 263 357 5.8E-14 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 Gene3D G3DSA:3.20.20.70 13 366 9.6E-42 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_05540 3786324bb93670dcf5200823d34a6df8 375 Pfam PF13186 Iron-sulfur cluster-binding domain 264 319 3.9E-6 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L14_08005 d7f888d15a764903967e6884f9780d83 172 PIRSF PIRSF016661 1 171 2.8E-48 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L14_08005 d7f888d15a764903967e6884f9780d83 172 Pfam PF02632 BioY family 27 167 1.3E-40 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L14_08005 d7f888d15a764903967e6884f9780d83 172 Gene3D G3DSA:1.10.1760.20 1 171 4.8E-56 T 23-10-2018 A3L14_10005 1a2a1b0459286f353a6eee53689be717 374 SUPERFAMILY SSF103473 2 360 1.18E-70 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_10005 1a2a1b0459286f353a6eee53689be717 374 Gene3D G3DSA:1.20.1250.20 1 191 4.9E-42 T 23-10-2018 A3L14_10005 1a2a1b0459286f353a6eee53689be717 374 Gene3D G3DSA:1.20.1250.20 192 370 5.0E-26 T 23-10-2018 A3L14_10005 1a2a1b0459286f353a6eee53689be717 374 Pfam PF07690 Major Facilitator Superfamily 11 219 9.4E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_09095 dc1e2111f3307ba8d79d2b9b14fe2f8d 284 SUPERFAMILY SSF161098 3 276 1.7E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_09095 dc1e2111f3307ba8d79d2b9b14fe2f8d 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 270 3.8E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_09095 dc1e2111f3307ba8d79d2b9b14fe2f8d 284 Gene3D G3DSA:1.10.3720.10 41 277 1.9E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_01725 b1c74050d72c0e524a25a1ef44dc860e 203 SUPERFAMILY SSF53335 4 201 3.46E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_01725 b1c74050d72c0e524a25a1ef44dc860e 203 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L14_01725 b1c74050d72c0e524a25a1ef44dc860e 203 Gene3D G3DSA:3.40.50.150 1 203 1.4E-61 T 23-10-2018 A3L14_01725 b1c74050d72c0e524a25a1ef44dc860e 203 Pfam PF05175 Methyltransferase small domain 31 126 6.4E-12 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 Pfam PF05048 Periplasmic copper-binding protein (NosD) 246 432 3.2E-48 T 23-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 120 142 4700.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 281 303 30.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 143 165 2.5 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 258 280 150.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 189 211 2300.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 350 397 3800.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 212 234 75.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 98 119 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 305 327 9.1 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 235 257 1500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 166 187 2200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SMART SM00710 328 349 500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 Pfam PF13229 Right handed beta helix region 75 216 7.5E-14 T 23-10-2018 IPR039448 Right handed beta helix domain A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 229 272 2.1E-6 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 305 343 2.1E-8 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 275 319 6.3E-8 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 182 227 9.6E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 322 364 8.3E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 137 180 9.2E-11 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 160 202 2.0E-6 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SUPERFAMILY SSF51126 41 232 6.11E-17 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 Gene3D G3DSA:2.160.20.10 26 239 2.3E-7 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 Gene3D G3DSA:2.160.20.10 243 388 3.7E-23 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_04375 403e7befeeb60050cce9cfffb8492aca 535 SUPERFAMILY SSF51126 204 423 7.18E-26 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_04650 2a6f3d694cc5b7b737c204d598c7abbb 213 Gene3D G3DSA:3.40.50.10480 1 186 4.0E-33 T 23-10-2018 A3L14_04650 2a6f3d694cc5b7b737c204d598c7abbb 213 SUPERFAMILY SSF52954 1 193 2.22E-35 T 23-10-2018 A3L14_04650 2a6f3d694cc5b7b737c204d598c7abbb 213 SMART SM00879 3 190 3.1E-16 T 23-10-2018 IPR007109 Brix domain A3L14_04650 2a6f3d694cc5b7b737c204d598c7abbb 213 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.966 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A3L14_03295 ec17463f44906199bace656d66700e6c 266 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 8 265 1.5E-74 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A3L14_03295 ec17463f44906199bace656d66700e6c 266 Gene3D G3DSA:3.40.50.10900 1 244 1.8E-75 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L14_03295 ec17463f44906199bace656d66700e6c 266 SUPERFAMILY SSF159659 3 256 7.19E-43 T 23-10-2018 A3L14_03295 ec17463f44906199bace656d66700e6c 266 Pfam PF09754 PAC2 family 19 242 4.1E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L14_04910 aa69fb570d41359b3578c32b1d5476c3 377 Gene3D G3DSA:3.40.50.2000 6 357 1.1E-136 T 23-10-2018 A3L14_04910 aa69fb570d41359b3578c32b1d5476c3 377 SUPERFAMILY SSF53756 2 364 1.49E-123 T 23-10-2018 A3L14_04910 aa69fb570d41359b3578c32b1d5476c3 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 360 8.8E-121 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L14_04910 aa69fb570d41359b3578c32b1d5476c3 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 362 2.3E-133 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L14_04910 aa69fb570d41359b3578c32b1d5476c3 377 Gene3D G3DSA:3.40.50.2000 183 347 1.1E-136 T 23-10-2018 A3L14_09800 0e1db374da92690df7a9321d5c180aec 155 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 116 1.1E-26 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A3L14_09800 0e1db374da92690df7a9321d5c180aec 155 Pfam PF13470 PIN domain 5 116 3.5E-15 T 23-10-2018 IPR002716 PIN domain A3L14_09800 0e1db374da92690df7a9321d5c180aec 155 SMART SM00670 4 119 1.2E-6 T 23-10-2018 IPR002716 PIN domain A3L14_09800 0e1db374da92690df7a9321d5c180aec 155 SUPERFAMILY SSF88723 4 125 1.51E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_03730 d66f7b77c6ad5df7e61abfa9b03b7525 85 Pfam PF09827 CRISPR associated protein Cas2 2 72 9.6E-23 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A3L14_03730 d66f7b77c6ad5df7e61abfa9b03b7525 85 Gene3D G3DSA:3.30.70.240 1 66 1.6E-30 T 23-10-2018 A3L14_03730 d66f7b77c6ad5df7e61abfa9b03b7525 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 72 4.8E-12 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L14_03730 d66f7b77c6ad5df7e61abfa9b03b7525 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 15.771 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A3L14_03730 d66f7b77c6ad5df7e61abfa9b03b7525 85 SUPERFAMILY SSF143430 2 81 7.06E-25 T 23-10-2018 A3L14_05445 3f416ad8af3609ae357a455962516293 476 Pfam PF09190 DALR domain 356 415 2.6E-16 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 SUPERFAMILY SSF47323 316 473 1.79E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_05445 3f416ad8af3609ae357a455962516293 476 SUPERFAMILY SSF52374 4 315 2.0E-111 T 23-10-2018 A3L14_05445 3f416ad8af3609ae357a455962516293 476 Gene3D G3DSA:3.40.50.620 1 305 5.5E-150 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_05445 3f416ad8af3609ae357a455962516293 476 SMART SM00840 356 417 2.0E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 4.0E-138 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 Gene3D G3DSA:1.20.120.640 306 473 3.7E-37 T 23-10-2018 A3L14_05445 3f416ad8af3609ae357a455962516293 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.793 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L14_05445 3f416ad8af3609ae357a455962516293 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 473 1.8E-180 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L14_01685 50190cab54af27a37fdaeca32843f810 119 Gene3D G3DSA:1.10.10.10 3 117 5.2E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01685 50190cab54af27a37fdaeca32843f810 119 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 3.7E-22 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_01685 50190cab54af27a37fdaeca32843f810 119 SUPERFAMILY SSF46785 15 114 2.0E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Gene3D G3DSA:3.30.1360.120 8 255 1.1E-88 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 1.1E-95 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 42.917 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 PIRSF PIRSF006487 1 398 4.9E-105 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 SUPERFAMILY SSF103025 2 307 2.51E-93 T 23-10-2018 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Gene3D G3DSA:2.40.30.110 309 383 6.5E-30 T 23-10-2018 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Gene3D G3DSA:3.30.70.1400 52 143 1.1E-88 T 23-10-2018 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Gene3D G3DSA:4.10.1250.10 256 305 1.8E-9 T 23-10-2018 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 4.2E-93 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 2.0E-25 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L14_10680 a315500891a6a0b5979d5d29032621e1 398 SUPERFAMILY SSF101790 300 392 1.08E-25 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A3L14_06495 c70f75c99ca44ac0e91e8a247d58ab89 358 Gene3D G3DSA:1.10.3210.10 1 257 2.4E-76 T 23-10-2018 A3L14_06495 c70f75c99ca44ac0e91e8a247d58ab89 358 SMART SM00471 46 156 2.0E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L14_06495 c70f75c99ca44ac0e91e8a247d58ab89 358 Pfam PF01966 HD domain 50 127 1.3E-10 T 23-10-2018 IPR006674 HD domain A3L14_06495 c70f75c99ca44ac0e91e8a247d58ab89 358 SUPERFAMILY SSF109604 1 356 1.27E-82 T 23-10-2018 A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 27 319 2.8E-100 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 Pfam PF13732 Domain of unknown function (DUF4162) 242 318 1.0E-6 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 Pfam PF00005 ABC transporter 31 174 2.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 SUPERFAMILY SSF52540 3 235 6.86E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 SMART SM00382 39 232 8.6E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_10635 adc2e4046db3e13ea34d72b88d6c951b 324 Gene3D G3DSA:3.40.50.300 2 280 9.9E-67 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 41 56 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A3L14_07495 f4334a9cc7130e885196c6140213324c 424 Gene3D G3DSA:1.10.3860.10 2 424 5.1E-162 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 Pfam PF00375 Sodium:dicarboxylate symporter family 16 412 6.4E-125 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 49 69 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 9.1E-46 T 23-10-2018 A3L14_07495 f4334a9cc7130e885196c6140213324c 424 SUPERFAMILY SSF118215 16 414 2.22E-121 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L14_09275 bc3af51b55dca0cee47b6ab3b6d91838 256 PIRSF PIRSF009320 92 256 4.4E-6 T 23-10-2018 A3L14_09275 bc3af51b55dca0cee47b6ab3b6d91838 256 PIRSF PIRSF009320 2 47 1.6E-14 T 23-10-2018 A3L14_09275 bc3af51b55dca0cee47b6ab3b6d91838 256 Gene3D G3DSA:3.40.50.300 1 255 2.8E-73 T 23-10-2018 A3L14_09275 bc3af51b55dca0cee47b6ab3b6d91838 256 SUPERFAMILY SSF52540 3 254 1.73E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09275 bc3af51b55dca0cee47b6ab3b6d91838 256 Pfam PF13614 AAA domain 4 178 3.3E-54 T 23-10-2018 IPR025669 AAA domain A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 Pfam PF00935 Ribosomal protein L44 16 92 4.7E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 4.0E-40 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 SUPERFAMILY SSF57829 1 93 2.93E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 Gene3D G3DSA:3.10.450.80 1 93 3.4E-31 T 23-10-2018 A3L14_03315 22334dcaa335269a4a30e9edb51c5895 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.954 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 Pfam PF00276 Ribosomal protein L23 5 73 3.6E-19 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 7.5E-39 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.45 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 Gene3D G3DSA:3.30.70.330 1 86 2.1E-36 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.581 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02485 724b6d52086f25b3e5acdcb3a148a3db 86 SUPERFAMILY SSF54189 4 78 1.47E-27 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_08140 32eff8262125b25a6740d8789a789a91 202 Pfam PF01895 PhoU domain 19 100 8.5E-9 T 23-10-2018 IPR026022 PhoU domain A3L14_08140 32eff8262125b25a6740d8789a789a91 202 Gene3D G3DSA:3.30.70.1450 117 202 3.5E-23 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_08140 32eff8262125b25a6740d8789a789a91 202 SUPERFAMILY SSF116726 108 191 4.32E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_08140 32eff8262125b25a6740d8789a789a91 202 Gene3D G3DSA:1.20.58.220 8 116 1.5E-22 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_08140 32eff8262125b25a6740d8789a789a91 202 Pfam PF02080 TrkA-C domain 125 191 2.0E-12 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L14_08140 32eff8262125b25a6740d8789a789a91 202 SUPERFAMILY SSF109755 11 158 1.7E-16 T 23-10-2018 A3L14_02350 f4243b5e5fbed00bfd802c57267304fc 104 Gene3D G3DSA:2.40.30.10 16 104 6.5E-18 T 23-10-2018 A3L14_02350 f4243b5e5fbed00bfd802c57267304fc 104 SUPERFAMILY SSF50447 27 99 1.01E-9 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_02350 f4243b5e5fbed00bfd802c57267304fc 104 Pfam PF14578 Elongation factor Tu domain 4 23 100 4.3E-17 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L14_04725 05694e2e8483b9bf4152af88be58a3a0 85 Gene3D G3DSA:1.20.1280.290 1 85 1.1E-10 T 23-10-2018 A3L14_08980 88d7f87ec6e0d45d31a973205342fd4c 123 Gene3D G3DSA:1.20.5.420 5 63 1.6E-21 T 23-10-2018 A3L14_08980 88d7f87ec6e0d45d31a973205342fd4c 123 Gene3D G3DSA:2.20.25.200 64 116 5.9E-23 T 23-10-2018 A3L14_08980 88d7f87ec6e0d45d31a973205342fd4c 123 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 106 26.851 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L14_08980 88d7f87ec6e0d45d31a973205342fd4c 123 PIRSF PIRSF004878 1 113 4.7E-45 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L14_08980 88d7f87ec6e0d45d31a973205342fd4c 123 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 97 2.5E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 SUPERFAMILY SSF56712 2 650 3.01E-163 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 SUPERFAMILY SSF57783 639 677 5.61E-5 T 23-10-2018 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 SMART SM00493 2 129 2.1E-20 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 3.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 3.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 3.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 3.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 3.2E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Gene3D G3DSA:1.10.290.10 279 406 2.0E-120 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 SMART SM00437 271 527 2.3E-102 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Gene3D G3DSA:3.40.50.140 1 154 7.7E-31 T 23-10-2018 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 638 675 1.6E-12 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 707 50.726 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Gene3D G3DSA:1.10.460.10 163 575 2.0E-120 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Pfam PF01751 Toprim domain 3 139 1.2E-18 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Pfam PF01131 DNA topoisomerase 156 564 1.4E-131 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 668 1.1E-283 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 Gene3D G3DSA:2.70.20.10 220 475 2.0E-120 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L14_03700 affb5a0aa6522ed478b1fb6ca89ac71f 719 SMART SM00436 131 226 5.0E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 Gene3D G3DSA:3.40.50.1820 377 632 2.9E-74 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 SUPERFAMILY SSF82171 24 366 1.28E-32 T 23-10-2018 A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 Pfam PF07676 WD40-like Beta Propeller Repeat 55 89 1.3E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 Gene3D G3DSA:2.120.10.30 23 145 2.5E-15 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 SUPERFAMILY SSF53474 374 631 1.15E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 Gene3D G3DSA:2.120.10.30 149 289 6.9E-8 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L14_07980 556a919ab09d95bfe56c4c668c342132 632 Pfam PF00326 Prolyl oligopeptidase family 421 631 5.7E-60 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L14_00385 8f6cdfa1054d57af722124b8caad501e 98 Gene3D G3DSA:1.10.10.10 1 98 4.9E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00385 8f6cdfa1054d57af722124b8caad501e 98 Pfam PF13601 Winged helix DNA-binding domain 17 93 1.9E-21 T 23-10-2018 IPR027395 Winged helix DNA-binding domain A3L14_00385 8f6cdfa1054d57af722124b8caad501e 98 SMART SM00418 6 93 0.008 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00385 8f6cdfa1054d57af722124b8caad501e 98 SUPERFAMILY SSF46785 10 96 3.43E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 Gene3D G3DSA:3.30.2130.30 1 189 8.3E-81 T 23-10-2018 A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 Gene3D G3DSA:3.40.50.150 190 365 1.2E-50 T 23-10-2018 A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 SUPERFAMILY SSF53335 179 359 2.47E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 Pfam PF02926 THUMP domain 19 182 3.9E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 SMART SM00981 86 182 8.2E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 7.7E-37 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L14_00270 b741a0975d1eb47038b8bcb4edc33457 365 SUPERFAMILY SSF143437 102 181 2.96E-9 T 23-10-2018 A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 4.6E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 Gene3D G3DSA:3.40.980.10 2 179 2.1E-55 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 SMART SM00852 4 179 1.2E-43 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 SUPERFAMILY SSF53218 1 206 4.19E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 1.5E-36 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_05770 ce877fe694be1fb6bd56d45b482895b2 252 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 38.944 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea A3L14_08605 ca9825f5a347fed132dc8295853f3b09 418 Pfam PF13635 Domain of unknown function (DUF4143) 220 356 3.6E-8 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L14_08605 ca9825f5a347fed132dc8295853f3b09 418 Gene3D G3DSA:3.40.50.300 22 81 5.5E-6 T 23-10-2018 A3L14_08605 ca9825f5a347fed132dc8295853f3b09 418 SUPERFAMILY SSF52540 36 198 7.11E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08605 ca9825f5a347fed132dc8295853f3b09 418 Pfam PF13173 AAA domain 35 164 6.4E-37 T 23-10-2018 A3L14_08605 ca9825f5a347fed132dc8295853f3b09 418 SMART SM00382 33 158 0.0059 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00030 a81e9a16473d99030aaa2e13f59c3e66 172 SUPERFAMILY SSF142913 3 170 2.59E-48 T 23-10-2018 A3L14_00030 a81e9a16473d99030aaa2e13f59c3e66 172 Gene3D G3DSA:3.30.930.10 1 170 1.6E-61 T 23-10-2018 A3L14_00030 a81e9a16473d99030aaa2e13f59c3e66 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 7.0E-66 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A3L14_08920 ec87be29178e5ee8e8ecdfbe50ce7946 533 Pfam PF01841 Transglutaminase-like superfamily 291 386 2.4E-6 T 23-10-2018 IPR002931 Transglutaminase-like A3L14_08920 ec87be29178e5ee8e8ecdfbe50ce7946 533 SUPERFAMILY SSF54001 276 454 9.07E-9 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L14_08920 ec87be29178e5ee8e8ecdfbe50ce7946 533 Gene3D G3DSA:3.10.620.30 269 401 2.5E-6 T 23-10-2018 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 SUPERFAMILY SSF88697 249 332 2.93E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 7.9E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Gene3D G3DSA:2.30.130.70 23 332 7.1E-146 T 23-10-2018 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 9.0E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Pfam PF01472 PUA domain 251 323 1.4E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 18 334 2.6E-134 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 120 180 5.5E-7 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 119 9.6E-16 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 SUPERFAMILY SSF55120 19 247 5.76E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.3E-22 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.159 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 SMART SM01136 4 63 9.5E-26 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 SMART SM00359 251 325 8.5E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_02630 0fd3ed906779bb78af0c2937968a59a6 334 Gene3D G3DSA:3.30.2350.10 40 243 7.1E-146 T 23-10-2018 A3L14_03175 774bee3e2ade55737562af8666353219 81 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 74 8.2E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 6.2E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 6.2E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 6.2E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 6.2E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 Gene3D G3DSA:2.40.50.970 1 74 1.4E-32 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L14_03175 774bee3e2ade55737562af8666353219 81 Pfam PF01455 HupF/HypC family 1 65 1.2E-29 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L14_03175 774bee3e2ade55737562af8666353219 81 SUPERFAMILY SSF159127 1 76 4.32E-28 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L14_03175 774bee3e2ade55737562af8666353219 81 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site A3L14_03565 a03968848eed30135905f4d806adcd6d 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Gene3D G3DSA:2.40.240.100 409 570 2.8E-45 T 23-10-2018 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 3 571 8.2E-213 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 405 1.8E-83 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 558 2.2E-29 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Gene3D G3DSA:2.40.240.10 418 516 2.8E-45 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Gene3D G3DSA:3.40.50.620 93 408 4.1E-119 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_03565 a03968848eed30135905f4d806adcd6d 571 SUPERFAMILY SSF50715 409 562 2.46E-31 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 SUPERFAMILY SSF52374 99 415 2.41E-90 T 23-10-2018 A3L14_03565 a03968848eed30135905f4d806adcd6d 571 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 569 39.664 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 Pfam PF02834 LigT like Phosphoesterase 7 91 1.3E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 Pfam PF02834 LigT like Phosphoesterase 98 174 7.3E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 2.6E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.096 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 SUPERFAMILY SSF55144 1 183 1.34E-45 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A3L14_01035 ead5cd513b8665aa65bb5fde5de9d176 184 Gene3D G3DSA:3.90.1140.10 1 183 6.4E-67 T 23-10-2018 A3L14_03520 ad92efeace55b9a9107380919c381b48 440 Gene3D G3DSA:1.20.1250.20 2 196 1.9E-30 T 23-10-2018 A3L14_03520 ad92efeace55b9a9107380919c381b48 440 Gene3D G3DSA:1.20.1250.20 222 425 6.5E-24 T 23-10-2018 A3L14_03520 ad92efeace55b9a9107380919c381b48 440 SUPERFAMILY SSF103473 8 423 8.5E-63 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_03520 ad92efeace55b9a9107380919c381b48 440 Pfam PF07690 Major Facilitator Superfamily 12 319 5.0E-41 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 SUPERFAMILY SSF50156 204 294 9.33E-23 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 Pfam PF13180 PDZ domain 204 272 1.1E-13 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 Gene3D G3DSA:2.30.42.10 203 291 1.8E-22 T 23-10-2018 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 Pfam PF02163 Peptidase family M50 115 363 6.4E-21 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 1.6E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 1.6E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 1.6E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 1.6E-19 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_00405 e4f2ad7cf2d8d0d6aac803979fef98aa 377 SMART SM00228 190 263 3.0E-7 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 11 447 1.2E-110 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 12 456 1.5E-234 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 Gene3D G3DSA:3.30.1110.20 18 198 1.8E-157 T 23-10-2018 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 4 456 44.262 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 PIRSF PIRSF015883 1 456 2.1E-200 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 SUPERFAMILY SSF53613 10 455 6.0E-156 T 23-10-2018 IPR029056 Ribokinase-like A3L14_08235 9b1781539f1f79194f596d201717dcfd 459 Gene3D G3DSA:3.40.1190.20 12 446 1.8E-157 T 23-10-2018 IPR029056 Ribokinase-like A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 3.3E-32 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Gene3D G3DSA:3.40.50.11540 163 341 3.7E-83 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SUPERFAMILY SSF54862 540 597 3.96E-15 T 23-10-2018 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 329 1.6E-50 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Gene3D G3DSA:3.40.30.10 5 97 4.1E-21 T 23-10-2018 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Gene3D G3DSA:3.10.20.600 342 436 2.3E-32 T 23-10-2018 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SUPERFAMILY SSF140490 435 531 5.62E-37 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SUPERFAMILY SSF52833 7 98 3.8E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Pfam PF10531 SLBB domain 353 401 1.1E-9 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SMART SM00928 439 484 7.5E-24 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Gene3D G3DSA:3.30.70.20 540 593 6.1E-13 T 23-10-2018 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SUPERFAMILY SSF142984 351 434 7.85E-25 T 23-10-2018 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Gene3D G3DSA:1.20.1440.230 437 539 2.2E-34 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Pfam PF00037 4Fe-4S binding domain 571 593 2.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 Pfam PF00037 4Fe-4S binding domain 540 563 2.6E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_02400 d0abf50138e46ac0585e78c7220e0230 600 SUPERFAMILY SSF142019 112 350 5.75E-97 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 Gene3D G3DSA:3.30.470.20 122 379 5.1E-93 T 23-10-2018 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 SUPERFAMILY SSF52440 1 133 4.12E-40 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 3.7E-41 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 Gene3D G3DSA:3.30.1490.20 152 218 5.1E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 PIRSF PIRSF004602 1 380 3.5E-142 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 SUPERFAMILY SSF56059 139 380 2.09E-76 T 23-10-2018 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 Gene3D G3DSA:3.40.50.20 1 121 1.5E-41 T 23-10-2018 A3L14_01400 a671264b14750deab3c9f6795e27d31b 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 2.0E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_05535 3b54b6778cb25fb68e83f36ff4b4a20c 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 416 2.5E-59 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05535 3b54b6778cb25fb68e83f36ff4b4a20c 447 Pfam PF01554 MatE 245 406 8.2E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05535 3b54b6778cb25fb68e83f36ff4b4a20c 447 Pfam PF01554 MatE 20 180 2.3E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05535 3b54b6778cb25fb68e83f36ff4b4a20c 447 PIRSF PIRSF006603 2 447 3.9E-117 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_06550 1018e58004ddfe4208559537875358fa 415 Pfam PF04409 Protein of unknown function (DUF530) 5 256 3.0E-23 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A3L14_06550 1018e58004ddfe4208559537875358fa 415 PIRSF PIRSF018863 1 415 4.9E-188 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 Gene3D G3DSA:3.30.70.60 1 91 5.5E-35 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 PIRSF PIRSF006521 3 91 5.3E-32 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.943 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 1.7E-20 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 SUPERFAMILY SSF54984 9 91 3.53E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 1.5E-21 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L14_01240 69486cbffe4c328cc774f7c1758d9354 91 SMART SM00888 5 91 8.2E-32 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 Pfam PF02222 ATP-grasp domain 126 302 4.8E-55 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L14_01385 5293598df6334f407c5cf3a15317546c 428 SUPERFAMILY SSF56059 117 323 2.69E-52 T 23-10-2018 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 Gene3D G3DSA:3.30.470.20 200 428 2.5E-80 T 23-10-2018 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 410 48.936 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 Gene3D G3DSA:3.40.50.20 1 127 1.9E-54 T 23-10-2018 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 Gene3D G3DSA:3.30.1490.20 128 199 1.6E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 409 1.3E-185 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 SUPERFAMILY SSF51246 338 409 5.96E-19 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L14_01385 5293598df6334f407c5cf3a15317546c 428 SUPERFAMILY SSF52440 8 114 2.3E-32 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L14_06660 cbf41f479f2e5fe7ee9855c40a62c74e 93 SUPERFAMILY SSF54285 1 93 4.3E-19 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L14_06660 cbf41f479f2e5fe7ee9855c40a62c74e 93 Pfam PF02597 ThiS family 3 93 2.7E-16 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L14_06660 cbf41f479f2e5fe7ee9855c40a62c74e 93 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 93 6.6E-21 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L14_06660 cbf41f479f2e5fe7ee9855c40a62c74e 93 Gene3D G3DSA:3.10.20.30 1 93 1.1E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 PRINTS PR00094 Adenylate kinase signature 158 173 5.7E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 PRINTS PR00094 Adenylate kinase signature 79 95 5.7E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 PRINTS PR00094 Adenylate kinase signature 4 17 5.7E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 PRINTS PR00094 Adenylate kinase signature 175 189 5.7E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 PRINTS PR00094 Adenylate kinase signature 32 46 5.7E-28 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 43.995 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 3.3E-16 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 5.1E-71 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 Gene3D G3DSA:3.40.50.300 1 219 1.8E-73 T 23-10-2018 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 Pfam PF00406 Adenylate kinase 5 188 4.1E-40 T 23-10-2018 A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 SUPERFAMILY SSF52540 1 212 2.17E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06670 ea622f1740a59117b89cc49ace68af85 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 SMART SM01118 1 166 1.0E-10 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 Pfam PF01928 CYTH domain 2 160 7.9E-25 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 165 3.5E-31 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 2.0E-38 T 23-10-2018 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 SUPERFAMILY SSF55154 1 164 5.89E-39 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L14_05945 4c1b47ac4048f90cf0c6c86ec8b63655 171 Gene3D G3DSA:2.40.320.10 1 170 1.4E-49 T 23-10-2018 A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 Gene3D G3DSA:3.40.50.300 232 374 9.5E-24 T 23-10-2018 A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 Pfam PF00271 Helicase conserved C-terminal domain 251 353 1.3E-12 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 Pfam PF00270 DEAD/DEAH box helicase 22 210 3.7E-16 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 SMART SM00487 16 237 1.2E-17 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 SUPERFAMILY SSF52540 33 364 1.84E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 SMART SM00490 276 354 8.4E-10 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 41 366 4.1E-57 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A3L14_03755 f48783d86ee8cbb103e54cbe075b66c3 677 Gene3D G3DSA:3.40.50.300 11 221 2.3E-20 T 23-10-2018 A3L14_05340 b71a00c8cbe2272288f51b778e85c767 113 Pfam PF14076 Domain of unknown function (DUF4258) 27 91 1.6E-9 T 23-10-2018 IPR025354 Protein of unknown function DUF4258 A3L14_10310 ac1dd5a148081cddb85dc88096aeed21 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 137 1.4E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_10310 ac1dd5a148081cddb85dc88096aeed21 137 Gene3D G3DSA:2.60.120.460 1 137 5.3E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L14_10310 ac1dd5a148081cddb85dc88096aeed21 137 PIRSF PIRSF004681 1 137 7.6E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_10310 ac1dd5a148081cddb85dc88096aeed21 137 SUPERFAMILY SSF111038 1 137 5.1E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L14_10310 ac1dd5a148081cddb85dc88096aeed21 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 7.5E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_08590 081f819be0366ddf2a540e012599bb57 388 Gene3D G3DSA:1.25.40.10 159 385 6.3E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_08590 081f819be0366ddf2a540e012599bb57 388 SUPERFAMILY SSF48452 9 314 3.6E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 SUPERFAMILY SSF46785 245 350 6.95E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 Pfam PF03008 Archaea bacterial proteins of unknown function 309 406 3.2E-35 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 Gene3D G3DSA:3.40.50.300 4 170 1.6E-31 T 23-10-2018 A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 Gene3D G3DSA:1.10.10.10 241 311 9.4E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 SUPERFAMILY SSF52980 339 406 1.39E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 SUPERFAMILY SSF52540 5 244 5.58E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04505 0117a19d27bd7b5a1c907d0782c32e26 452 Pfam PF01637 ATPase domain predominantly from Archaea 7 201 9.0E-23 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_04460 0e8bef6e59cd8003373f828d253af556 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 151 2.0E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_04460 0e8bef6e59cd8003373f828d253af556 192 SUPERFAMILY SSF56300 22 154 8.78E-19 T 23-10-2018 A3L14_04460 0e8bef6e59cd8003373f828d253af556 192 Gene3D G3DSA:3.60.21.10 15 139 8.5E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 363 399 5.6E-5 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 1330 1369 5.7E-7 T 23-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 1263 1522 4.87E-26 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Pfam PF05048 Periplasmic copper-binding protein (NosD) 1406 1530 3.0E-31 T 23-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Pfam PF05048 Periplasmic copper-binding protein (NosD) 1001 1246 3.5E-34 T 23-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 358 531 3.14E-14 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Pfam PF13229 Right handed beta helix region 610 793 1.1E-13 T 23-10-2018 IPR039448 Right handed beta helix domain A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Pfam PF13229 Right handed beta helix region 303 541 5.4E-9 T 23-10-2018 IPR039448 Right handed beta helix domain A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 85 328 2.51E-8 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Gene3D G3DSA:2.160.20.10 966 1231 8.2E-9 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Gene3D G3DSA:2.160.20.10 1286 1501 5.5E-24 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Gene3D G3DSA:2.160.20.10 736 944 2.1E-7 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 843 871 2500.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1359 1381 8.9 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1043 1064 1900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 806 825 1100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 435 457 1100.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1313 1335 670.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 488 510 0.035 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1167 1196 590.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 751 773 86.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1119 1140 1300.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 309 330 1600.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1451 1471 4800.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 249 270 900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 774 796 12.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 385 432 650.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1382 1404 60.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1093 1114 3400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1336 1358 1.1 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 593 616 9900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1429 1450 650.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 900 920 7700.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 225 246 5400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 363 384 0.043 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 177 198 270.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1143 1164 2200.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 287 308 62.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1021 1042 2900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 640 670 270.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1406 1427 1300.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 1067 1089 270.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 617 639 1400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00710 570 592 3000.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 542 698 1.19E-16 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Gene3D G3DSA:2.60.40.10 1537 1629 6.1E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 1002 1238 2.18E-15 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SUPERFAMILY SSF51126 737 929 2.01E-11 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00722 286 431 63.0 T 23-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00722 1262 1403 7.1E-4 T 23-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 SMART SM00722 518 722 32.0 T 23-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain A3L14_07730 19fd66daeac3103fe9de4465776b074d 1724 Gene3D G3DSA:2.160.20.10 549 719 2.5E-10 T 23-10-2018 IPR012334 Pectin lyase fold A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 SMART SM00729 79 374 3.4E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 Gene3D G3DSA:3.40.630.30 422 572 4.2E-8 T 23-10-2018 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 SUPERFAMILY SSF55729 449 568 2.16E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 Pfam PF16199 Radical_SAM C-terminal domain 335 414 2.3E-25 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 Pfam PF00583 Acetyltransferase (GNAT) family 459 561 5.1E-8 T 23-10-2018 IPR000182 GNAT domain A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 14 572 1.5E-262 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 PIRSF PIRSF005669 1 573 1.4E-248 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 Pfam PF04055 Radical SAM superfamily 86 319 1.2E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 SUPERFAMILY SSF102114 84 381 3.53E-34 T 23-10-2018 A3L14_00645 ade1e0b8ab30aa63288da8d260ac02be 591 Gene3D G3DSA:3.80.30.20 233 382 1.2E-12 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L14_01545 33a02d89519fbf0944c8678283534608 186 Pfam PF00575 S1 RNA binding domain 78 150 2.1E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L14_01545 33a02d89519fbf0944c8678283534608 186 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 3.2E-68 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A3L14_01545 33a02d89519fbf0944c8678283534608 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 4.0E-19 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A3L14_01545 33a02d89519fbf0944c8678283534608 186 SUPERFAMILY SSF50249 80 179 5.89E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_01545 33a02d89519fbf0944c8678283534608 186 Gene3D G3DSA:3.30.1490.120 1 81 2.0E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L14_01545 33a02d89519fbf0944c8678283534608 186 SUPERFAMILY SSF88798 1 78 1.06E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L14_01545 33a02d89519fbf0944c8678283534608 186 Gene3D G3DSA:2.40.50.140 82 186 8.8E-33 T 23-10-2018 A3L14_01545 33a02d89519fbf0944c8678283534608 186 SMART SM00316 80 166 7.6E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 Gene3D G3DSA:3.40.50.11850 100 208 4.3E-40 T 23-10-2018 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 Gene3D G3DSA:3.40.50.11840 5 98 7.3E-32 T 23-10-2018 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 PIRSF PIRSF004967 1 333 1.6E-81 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 1.1E-111 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 Gene3D G3DSA:3.40.50.11860 212 313 6.6E-35 T 23-10-2018 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 7 313 7.6E-92 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_01705 226e818f5e3263a2bfb91a28784d4f83 340 Pfam PF01866 Putative diphthamide synthesis protein 26 317 4.2E-76 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 SUPERFAMILY SSF82861 99 175 1.06E-5 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 Gene3D G3DSA:2.30.30.60 192 241 1.2E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 SUPERFAMILY SSF82689 243 342 5.1E-31 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 SUPERFAMILY SSF50182 177 241 3.6E-18 T 23-10-2018 IPR010920 LSM domain superfamily A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 206 240 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 Pfam PF00924 Mechanosensitive ion channel 132 331 1.7E-59 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L14_01745 0bdd1692d8461aae7e7fa08e12ac3836 362 Gene3D G3DSA:3.30.70.100 242 335 1.9E-27 T 23-10-2018 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 121 204 19.315 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 55 108 8.0E-21 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 SUPERFAMILY SSF101386 123 208 1.46E-21 T 23-10-2018 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 124 207 9.8E-16 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Gene3D G3DSA:1.10.287.1080 120 209 1.3E-26 T 23-10-2018 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Gene3D G3DSA:3.10.20.400 2 96 1.9E-34 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 209 35.813 T 23-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 SUPERFAMILY SSF141734 4 114 6.93E-42 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 124 204 4.9E-28 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 2.0E-31 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L14_07450 c23735e747142777f7c9a87a2181fefd 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 109 29.131 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 316 324 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 PRINTS PR00131 Glycosyl hydrolase family 1 signature 256 270 2.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 PRINTS PR00131 Glycosyl hydrolase family 1 signature 316 324 2.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 385 2.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 PRINTS PR00131 Glycosyl hydrolase family 1 signature 349 366 2.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 PRINTS PR00131 Glycosyl hydrolase family 1 signature 328 339 2.8E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 Gene3D G3DSA:3.20.20.80 1 417 7.1E-141 T 23-10-2018 A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 SUPERFAMILY SSF51445 3 408 1.4E-127 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_09740 adecf8c923ad2ce4b6a2dce29ef2ddd4 418 Pfam PF00232 Glycosyl hydrolase family 1 3 402 1.8E-86 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 Pfam PF01896 DNA primase small subunit 96 317 1.7E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 354 23.103 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 Gene3D G3DSA:1.10.8.160 176 288 2.9E-113 T 23-10-2018 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 340 5.9E-58 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 SUPERFAMILY SSF56747 6 351 1.68E-90 T 23-10-2018 A3L14_00860 e26101fc078ee72170089acd7a17136d 357 Gene3D G3DSA:3.90.920.10 9 337 2.9E-113 T 23-10-2018 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 Gene3D G3DSA:1.10.287.10 83 151 4.4E-32 T 23-10-2018 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 SMART SM01387 70 149 1.6E-26 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.634 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 Pfam PF00312 Ribosomal protein S15 73 148 8.5E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 SUPERFAMILY SSF47060 66 142 8.54E-25 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 SMART SM01386 1 60 1.7E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 Gene3D G3DSA:1.10.8.1030 36 82 4.5E-21 T 23-10-2018 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 132 0.003 T 23-10-2018 A3L14_05015 c07ed08d2bef1cc8efc792caa9158972 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 4.2E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 Gene3D G3DSA:3.50.50.60 135 256 4.7E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 320 3.6E-121 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 SUPERFAMILY SSF51905 15 319 1.23E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 309 3.0E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 153 173 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 71 81 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 271 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 158 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 228 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 302 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 6.5E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 Gene3D G3DSA:3.50.50.60 18 314 4.7E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 8.2E-40 T 23-10-2018 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 8.2E-40 T 23-10-2018 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 8.2E-40 T 23-10-2018 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 8.2E-40 T 23-10-2018 A3L14_11420 518fae1f2f19f6bebc62b2ca2e7d0cc0 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 8.2E-40 T 23-10-2018 A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 SUPERFAMILY SSF51735 3 152 7.13E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 SUPERFAMILY SSF55347 133 288 1.59E-25 T 23-10-2018 A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 21 122 5.5E-20 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 Gene3D G3DSA:3.40.50.720 21 309 1.2E-72 T 23-10-2018 A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 Gene3D G3DSA:3.30.360.10 130 331 1.2E-72 T 23-10-2018 A3L14_09105 36cbb417c23414d9d827ef2e53911f9a 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 252 1.9E-9 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 Pfam PF03008 Archaea bacterial proteins of unknown function 307 402 2.3E-27 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 SUPERFAMILY SSF52980 337 397 2.55E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 Gene3D G3DSA:1.10.10.10 234 314 3.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 SUPERFAMILY SSF52540 3 241 1.62E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 SUPERFAMILY SSF46785 240 299 1.23E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 236 302 3.9E-7 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 3.2E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_07195 bb9f663fe294941b6ca4ee8cd85a53ab 455 Gene3D G3DSA:3.40.50.300 2 169 2.4E-27 T 23-10-2018 A3L14_10385 ec73624bb07d06440fa2e6514c1af385 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 7.0E-71 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L14_10385 ec73624bb07d06440fa2e6514c1af385 261 PIRSF PIRSF005956 1 259 5.1E-97 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L14_10385 ec73624bb07d06440fa2e6514c1af385 261 SUPERFAMILY SSF51366 11 251 3.14E-26 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_10385 ec73624bb07d06440fa2e6514c1af385 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 257 3.3E-107 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L14_10385 ec73624bb07d06440fa2e6514c1af385 261 Pfam PF03437 BtpA family 5 255 8.8E-106 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 SUPERFAMILY SSF54909 65 150 4.96E-22 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 SMART SM00344 5 111 7.4E-51 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 5.0E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 Gene3D G3DSA:3.30.70.920 57 150 2.0E-28 T 23-10-2018 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.7E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.7E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.7E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 SUPERFAMILY SSF46785 5 65 3.55E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.1E-17 T 23-10-2018 A3L14_09665 8e812a9556ea22ae7dcd19d1dc979aae 150 Gene3D G3DSA:1.10.10.10 2 55 4.7E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 SUPERFAMILY SSF52540 6 144 1.6E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 Gene3D G3DSA:3.30.60.20 145 196 2.5E-25 T 23-10-2018 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 Gene3D G3DSA:3.40.50.300 2 143 6.0E-46 T 23-10-2018 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 PIRSF PIRSF035805 4 196 9.2E-66 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 177 190 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 SUPERFAMILY SSF57716 145 194 4.09E-16 T 23-10-2018 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 Hamap MF_00124 Thymidine kinase [tdk]. 5 193 36.215 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L14_09165 c666d9e0f7acec0853db1742a6a6bac7 196 Pfam PF00265 Thymidine kinase 7 190 1.3E-52 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L14_09250 1665781d819ce879200783c83efb2651 200 Gene3D G3DSA:3.30.1360.30 83 191 7.7E-43 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L14_09250 1665781d819ce879200783c83efb2651 200 Gene3D G3DSA:1.10.10.10 1 82 3.8E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09250 1665781d819ce879200783c83efb2651 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 190 6.5E-55 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A3L14_09250 1665781d819ce879200783c83efb2651 200 SUPERFAMILY SSF55261 88 198 4.84E-37 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L14_09250 1665781d819ce879200783c83efb2651 200 SUPERFAMILY SSF46785 18 76 1.28E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 SUPERFAMILY SSF74650 5 238 3.45E-41 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 686 735 3.7E-10 T 23-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Gene3D G3DSA:1.50.10.10 288 669 3.9E-133 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 295 682 6.1E-115 T 23-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 238 5.7E-41 T 23-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Gene3D G3DSA:2.70.98.40 3 240 3.2E-42 T 23-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 SUPERFAMILY SSF48208 243 723 1.36E-122 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 PIRSF PIRSF036289 1 743 2.1E-195 T 23-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase A3L14_04400 792184d7d5cd9a7ae559ed3215b89037 747 Gene3D G3DSA:2.60.420.10 671 740 6.6E-16 T 23-10-2018 A3L14_04075 5e5a2b1b1d4f124b3b0237481eca8d74 128 Pfam PF11469 Ribonuclease III 10 127 3.2E-57 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A3L14_04075 5e5a2b1b1d4f124b3b0237481eca8d74 128 SUPERFAMILY SSF69065 7 127 2.14E-49 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A3L14_04075 5e5a2b1b1d4f124b3b0237481eca8d74 128 Gene3D G3DSA:1.10.1520.20 2 127 1.4E-45 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A3L14_11055 98d842ee127df092666119d902b990bf 63 Pfam PF12802 MarR family 13 51 5.7E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L14_11055 98d842ee127df092666119d902b990bf 63 SUPERFAMILY SSF46785 6 52 2.06E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_11055 98d842ee127df092666119d902b990bf 63 Gene3D G3DSA:1.10.10.10 1 56 5.3E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 Gene3D G3DSA:2.10.260.30 1 69 7.0E-28 T 23-10-2018 A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 SUPERFAMILY SSF46906 66 138 6.67E-23 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 6.0E-23 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 SUPERFAMILY SSF54747 3 82 3.92E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 8.9E-23 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 Gene3D G3DSA:1.10.10.250 73 163 1.2E-35 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 SMART SM00649 5 138 4.9E-65 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03620 89392c0a1e45bab8d13ee6dd20015ed3 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.506 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 Pfam PF01957 NfeD-like C-terminal, partner-binding 296 440 1.6E-32 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 SUPERFAMILY SSF52096 11 192 1.48E-30 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 Gene3D G3DSA:2.40.50.140 377 447 3.3E-21 T 23-10-2018 A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 SUPERFAMILY SSF141322 373 442 1.44E-15 T 23-10-2018 A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 Gene3D G3DSA:3.90.226.10 22 245 4.2E-68 T 23-10-2018 A3L14_08415 ad8f6f90fed97164c7c8de973a71ab52 447 Pfam PF00574 Clp protease 55 192 8.6E-10 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Hamap MF_00900 GTPase HflX [hflX]. 17 391 42.679 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Gene3D G3DSA:3.40.50.11060 8 129 2.9E-33 T 23-10-2018 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Gene3D G3DSA:3.40.50.300 188 361 5.3E-41 T 23-10-2018 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 356 6.5E-94 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 9.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 9.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Pfam PF01926 50S ribosome-binding GTPase 189 307 8.5E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 SUPERFAMILY SSF52540 188 401 2.7E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 PIRSF PIRSF006809 1 420 3.9E-122 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Pfam PF13167 GTP-binding GTPase N-terminal 17 100 2.3E-23 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 7.5E-19 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A3L14_10565 4283f371e8fe1a747d6e408102b20311 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 333 1.4E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_07670 3a26515105eb24f8c6dbe6de7ec123f9 180 Pfam PF03266 NTPase 4 168 2.1E-52 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L14_07670 3a26515105eb24f8c6dbe6de7ec123f9 180 SUPERFAMILY SSF52540 5 149 1.54E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07670 3a26515105eb24f8c6dbe6de7ec123f9 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 29.038 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L14_07670 3a26515105eb24f8c6dbe6de7ec123f9 180 Gene3D G3DSA:3.40.50.300 3 176 7.2E-40 T 23-10-2018 A3L14_07670 3a26515105eb24f8c6dbe6de7ec123f9 180 SMART SM00382 1 158 3.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 822 843 1.0E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 461 570 8.4E-17 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SUPERFAMILY SSF51294 460 842 4.51E-40 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SUPERFAMILY SSF48168 9 150 1.91E-12 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 2.4E-27 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Pfam PF03477 ATP cone domain 5 93 9.8E-22 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 842 1162 6.7E-127 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SUPERFAMILY SSF51998 270 1164 1.81E-149 T 23-10-2018 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Gene3D G3DSA:3.20.70.20 822 1168 9.2E-118 T 23-10-2018 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Gene3D G3DSA:3.20.70.20 214 460 2.9E-78 T 23-10-2018 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SMART SM00305 803 848 1.2E-9 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SMART SM00306 459 590 1.3E-24 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 700 712 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 557 570 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 606 618 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 837 846 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 819 836 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 PRINTS PR00379 Intein signature 727 742 6.9E-28 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 SUPERFAMILY SSF55608 682 793 1.39E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Pfam PF14890 Intein splicing domain 541 842 2.5E-20 T 23-10-2018 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Gene3D G3DSA:3.20.70.20 61 164 4.8E-6 T 23-10-2018 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Pfam PF14528 LAGLIDADG-like domain 700 788 4.2E-20 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 1153 2.7E-230 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L14_01055 97975854842b3a9c8c7dfb6a5330736b 1291 Gene3D G3DSA:3.10.28.10 603 758 4.3E-32 T 23-10-2018 IPR027434 Homing endonuclease A3L14_04550 cb58b0f9c2541fc3ba69d4cec5381755 207 Pfam PF00005 ABC transporter 22 159 2.2E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_04550 cb58b0f9c2541fc3ba69d4cec5381755 207 SUPERFAMILY SSF52540 5 189 4.79E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04550 cb58b0f9c2541fc3ba69d4cec5381755 207 Gene3D G3DSA:3.40.50.300 2 201 6.6E-36 T 23-10-2018 A3L14_04550 cb58b0f9c2541fc3ba69d4cec5381755 207 SMART SM00382 28 198 1.5E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04550 cb58b0f9c2541fc3ba69d4cec5381755 207 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_03990 670ab12914872286e760c5da3da6c6e2 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 3.1E-112 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A3L14_03990 670ab12914872286e760c5da3da6c6e2 493 Pfam PF02386 Cation transport protein 59 479 1.1E-66 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 Gene3D G3DSA:3.50.50.60 1 367 4.4E-57 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 SUPERFAMILY SSF51905 3 283 4.73E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 Pfam PF01494 FAD binding domain 3 162 2.7E-14 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 8.9E-54 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.4E-12 T 23-10-2018 A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.4E-12 T 23-10-2018 A3L14_00370 486daa7bc708f7284af0ef9c1d8d107e 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.4E-12 T 23-10-2018 A3L14_00280 08a08c0db0928c42abcd5d026f932c5f 117 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 3.1E-20 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A3L14_05115 59d5fdfd7217bb7e7d06c117b07742d2 367 Pfam PF17179 4Fe-4S dicluster domain 233 326 1.6E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_05115 59d5fdfd7217bb7e7d06c117b07742d2 367 SUPERFAMILY SSF46548 218 333 3.03E-11 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_05115 59d5fdfd7217bb7e7d06c117b07742d2 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_05115 59d5fdfd7217bb7e7d06c117b07742d2 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.043 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 Gene3D G3DSA:3.30.300.20 74 144 5.9E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 Pfam PF07650 KH domain 14 94 8.2E-18 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 8.6E-60 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 SUPERFAMILY SSF54814 13 74 7.85E-12 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 Gene3D G3DSA:3.30.300.20 2 73 2.1E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 SMART SM00322 32 115 0.0014 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_03400 e823e54c1337bb07f1e1d07c91917e05 145 SUPERFAMILY SSF54814 88 141 6.54E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_00780 0f04ca747e586906fa061059918d60be 233 Gene3D G3DSA:2.40.30.10 3 83 3.8E-12 T 23-10-2018 A3L14_00780 0f04ca747e586906fa061059918d60be 233 Gene3D G3DSA:3.40.50.80 86 196 1.4E-24 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_00780 0f04ca747e586906fa061059918d60be 233 PIRSF PIRSF006816 1 232 3.1E-73 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L14_00780 0f04ca747e586906fa061059918d60be 233 SUPERFAMILY SSF63380 4 85 5.38E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L14_00780 0f04ca747e586906fa061059918d60be 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.211 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A3L14_00780 0f04ca747e586906fa061059918d60be 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 2.2E-5 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L14_00780 0f04ca747e586906fa061059918d60be 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 2.7E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L14_00780 0f04ca747e586906fa061059918d60be 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 2.7E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L14_00780 0f04ca747e586906fa061059918d60be 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 2.7E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L14_00780 0f04ca747e586906fa061059918d60be 233 SUPERFAMILY SSF52343 80 228 2.1E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_00780 0f04ca747e586906fa061059918d60be 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 1.7E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L14_09575 9a52f09d5dab5487689900bda67be219 350 SUPERFAMILY SSF53901 174 348 4.66E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09575 9a52f09d5dab5487689900bda67be219 350 SUPERFAMILY SSF53901 11 169 4.19E-33 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09575 9a52f09d5dab5487689900bda67be219 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 304 6.0E-11 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L14_09575 9a52f09d5dab5487689900bda67be219 350 Hamap MF_01409 UPF0219 protein . 10 350 60.797 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L14_09575 9a52f09d5dab5487689900bda67be219 350 Gene3D G3DSA:3.40.47.10 9 348 1.3E-71 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09575 9a52f09d5dab5487689900bda67be219 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 350 1.7E-191 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 Gene3D G3DSA:1.20.120.420 11 156 1.4E-45 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 SUPERFAMILY SSF100950 12 350 7.67E-114 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 1.1E-114 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 5.8E-128 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 Pfam PF01008 Initiation factor 2 subunit family 55 343 4.4E-82 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.665 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_07675 3913e7dddbc10e73ab2c4b86621d74e5 357 Gene3D G3DSA:3.40.50.10470 159 356 3.2E-61 T 23-10-2018 A3L14_00600 c75a82f2f4e1a2691ba12671dbee3d14 190 Pfam PF12389 Camelysin metallo-endopeptidase 11 96 2.2E-7 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L14_00600 c75a82f2f4e1a2691ba12671dbee3d14 190 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 42 3.7E-11 T 23-10-2018 IPR023833 Signal peptide, camelysin A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Gene3D G3DSA:3.30.1490.20 3 197 8.3E-73 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 PIRSF PIRSF000854 1 775 2.6E-206 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Gene3D G3DSA:3.50.30.10 355 461 6.1E-43 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 8.0E-29 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 729 741 1.3E-13 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 676 691 1.3E-13 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 531 1.3E-13 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 1.3E-13 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Gene3D G3DSA:3.20.20.60 462 783 1.9E-102 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 351 5.5E-119 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 771 9.8E-289 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 SUPERFAMILY SSF56059 3 381 5.65E-106 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 676 694 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 SUPERFAMILY SSF52009 353 461 5.89E-37 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 SUPERFAMILY SSF51621 485 778 2.88E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Gene3D G3DSA:3.30.470.20 198 354 5.4E-53 T 23-10-2018 A3L14_03080 9601678719903f2d8b9ab2de726ad227 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 476 770 7.8E-96 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L14_05510 6e6c4fba53b41aaec3c382748b070c2a 429 Pfam PF01964 Radical SAM ThiC family 2 420 1.0E-179 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L14_05510 6e6c4fba53b41aaec3c382748b070c2a 429 Gene3D G3DSA:3.20.20.540 44 362 1.3E-136 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L14_05510 6e6c4fba53b41aaec3c382748b070c2a 429 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 6.9E-185 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L14_05510 6e6c4fba53b41aaec3c382748b070c2a 429 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 86.857 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PIRSF PIRSF006540 1 226 1.2E-100 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 Pfam PF01269 Fibrillarin 5 225 1.8E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 SUPERFAMILY SSF53335 5 226 1.57E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 Gene3D G3DSA:3.30.200.20 1 50 3.9E-23 T 23-10-2018 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 Gene3D G3DSA:3.40.50.150 51 226 2.0E-75 T 23-10-2018 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 23 42 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 46 65 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 73 94 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 204 225 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 123 152 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 153 182 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 PRINTS PR00052 Fibrillarin signature 98 115 5.7E-80 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 SMART SM01206 3 226 8.3E-144 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_09585 495da73419d0e3cbc93407ac1e00d05b 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.308 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L14_08770 db86aacef35b50f451674b39deaea2a7 235 Pfam PF01973 Protein of unknown function DUF115 52 186 3.2E-26 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A3L14_08770 db86aacef35b50f451674b39deaea2a7 235 SUPERFAMILY SSF63999 53 107 9.55E-8 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A3L14_08770 db86aacef35b50f451674b39deaea2a7 235 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.388 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A3L14_00360 5bac9cbd207acc0b7d39c39551fb9c65 484 SUPERFAMILY SSF48239 396 461 5.69E-5 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_00360 5bac9cbd207acc0b7d39c39551fb9c65 484 Gene3D G3DSA:1.50.10.20 113 236 3.8E-9 T 23-10-2018 A3L14_00360 5bac9cbd207acc0b7d39c39551fb9c65 484 Gene3D G3DSA:1.50.10.20 39 112 5.7E-6 T 23-10-2018 A3L14_00360 5bac9cbd207acc0b7d39c39551fb9c65 484 SUPERFAMILY SSF48239 55 215 1.88E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_00360 5bac9cbd207acc0b7d39c39551fb9c65 484 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 47 168 2.4E-7 T 23-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 SUPERFAMILY SSF54821 86 186 3.53E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 SMART SM00322 38 104 3.6E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 SUPERFAMILY SSF54814 7 93 7.85E-26 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 2.6E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 Pfam PF07650 KH domain 17 88 6.0E-16 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.5E-94 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.41 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 Gene3D G3DSA:3.30.300.20 1 86 3.3E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_02505 b62c0adaad9d69c1d2cad4e040f135de 209 Gene3D G3DSA:3.30.1140.32 87 209 5.7E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 PIRSF PIRSF008955 12 263 5.9E-100 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 Gene3D G3DSA:1.10.340.30 41 188 5.0E-79 T 23-10-2018 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 SUPERFAMILY SSF48150 16 244 1.1E-77 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 38.797 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 Gene3D G3DSA:1.10.1670.10 20 249 5.0E-79 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L14_04185 c3be63e6639d79ad2a525f881b9cb4b3 263 Pfam PF09171 N-glycosylase/DNA lyase 23 241 5.8E-81 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.994 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 PIRSF PIRSF002133 19 147 2.4E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_03395 76caf095d0eb8849ecc7d31dfb1d2a61 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 23-10-2018 A3L14_09150 00c9239a9f804e7bfc09f63ac9368344 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.141 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09150 00c9239a9f804e7bfc09f63ac9368344 67 Pfam PF00833 Ribosomal S17 1 64 8.2E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09150 00c9239a9f804e7bfc09f63ac9368344 67 SUPERFAMILY SSF116820 1 60 1.83E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09150 00c9239a9f804e7bfc09f63ac9368344 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09150 00c9239a9f804e7bfc09f63ac9368344 67 Gene3D G3DSA:1.10.60.20 1 62 2.7E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 Gene3D G3DSA:3.40.50.300 3 243 3.1E-75 T 23-10-2018 A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 SUPERFAMILY SSF52540 1 235 1.61E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 157 234 4.6E-8 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 Pfam PF13614 AAA domain 3 145 4.2E-27 T 23-10-2018 IPR025669 AAA domain A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 PIRSF PIRSF003092 1 242 1.7E-57 T 23-10-2018 IPR025501 ATP binding protein MinD A3L14_08560 f291e9b177d4dd476c03c886b3bdc37d 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 236 1.4E-100 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 PIRSF PIRSF038945 39 389 2.0E-91 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 TIGRFAM TIGR00260 thrC: threonine synthase 57 381 2.5E-66 T 23-10-2018 IPR004450 Threonine synthase-like A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 Gene3D G3DSA:3.40.50.1100 110 204 3.9E-113 T 23-10-2018 A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 SUPERFAMILY SSF53686 4 387 6.55E-96 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 Gene3D G3DSA:3.40.50.1100 63 380 3.9E-113 T 23-10-2018 A3L14_09160 f5f9e5b1c258fc9d9403d7cbdb38729a 389 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 374 2.7E-75 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_10285 aa92f441dab700d15ece571eee1c4aa9 82 Pfam PF13396 Phospholipase_D-nuclease N-terminal 18 58 8.1E-8 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal A3L14_00365 d1ce4c081aa07d704c0bed53cfcbd9f5 121 SUPERFAMILY SSF88697 1 108 4.64E-37 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_00365 d1ce4c081aa07d704c0bed53cfcbd9f5 121 Gene3D G3DSA:2.30.130.30 2 109 1.1E-42 T 23-10-2018 A3L14_00365 d1ce4c081aa07d704c0bed53cfcbd9f5 121 Pfam PF04266 ASCH domain 7 108 2.2E-15 T 23-10-2018 IPR007374 ASCH domain A3L14_00365 d1ce4c081aa07d704c0bed53cfcbd9f5 121 SMART SM01022 6 109 5.9E-17 T 23-10-2018 IPR007374 ASCH domain A3L14_00365 d1ce4c081aa07d704c0bed53cfcbd9f5 121 PIRSF PIRSF016134 2 111 5.8E-45 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 Pfam PF02110 Hydroxyethylthiazole kinase family 8 252 4.4E-85 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PIRSF PIRSF000513 3 263 6.2E-100 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 162 179 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 16 23 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 86 103 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 29 50 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 117 131 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 60 68 1.9E-44 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 Gene3D G3DSA:3.40.1190.20 1 263 6.1E-99 T 23-10-2018 IPR029056 Ribokinase-like A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 SUPERFAMILY SSF53613 4 259 5.46E-65 T 23-10-2018 IPR029056 Ribokinase-like A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 10 255 33.784 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05495 0c7eeddae10ac224555a11071ec2912a 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 8 253 1.8E-97 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_03530 a8bc6df33b564bb7d314eea6db0ced93 288 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 81 162 2.6E-12 T 23-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A3L14_03530 a8bc6df33b564bb7d314eea6db0ced93 288 SUPERFAMILY SSF53474 18 288 2.34E-50 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_03530 a8bc6df33b564bb7d314eea6db0ced93 288 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 125 155 - T 23-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A3L14_03530 a8bc6df33b564bb7d314eea6db0ced93 288 Gene3D G3DSA:3.40.50.1820 43 288 7.0E-43 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_05880 733c5b16e66adccf920667007b28225e 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 6.5E-112 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A3L14_05880 733c5b16e66adccf920667007b28225e 357 SUPERFAMILY SSF55315 251 356 7.53E-29 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_05880 733c5b16e66adccf920667007b28225e 357 Pfam PF03463 eRF1 domain 1 1 127 9.2E-30 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L14_05880 733c5b16e66adccf920667007b28225e 357 Pfam PF03464 eRF1 domain 2 136 248 5.6E-16 T 23-10-2018 IPR005141 eRF1 domain 2 A3L14_05880 733c5b16e66adccf920667007b28225e 357 Gene3D G3DSA:3.30.420.60 133 257 5.6E-35 T 23-10-2018 A3L14_05880 733c5b16e66adccf920667007b28225e 357 SUPERFAMILY SSF159065 1 129 2.62E-36 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L14_05880 733c5b16e66adccf920667007b28225e 357 Gene3D G3DSA:3.30.1330.30 258 357 1.1E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_05880 733c5b16e66adccf920667007b28225e 357 SUPERFAMILY SSF53137 131 259 1.09E-30 T 23-10-2018 A3L14_05880 733c5b16e66adccf920667007b28225e 357 Pfam PF03465 eRF1 domain 3 261 356 4.3E-25 T 23-10-2018 IPR005142 eRF1 domain 3 A3L14_05880 733c5b16e66adccf920667007b28225e 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.079 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A3L14_05880 733c5b16e66adccf920667007b28225e 357 SMART SM01194 1 129 4.5E-49 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L14_05880 733c5b16e66adccf920667007b28225e 357 Gene3D G3DSA:2.30.30.870 1 129 4.6E-39 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 Gene3D G3DSA:3.40.1190.20 1 316 5.5E-104 T 23-10-2018 IPR029056 Ribokinase-like A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 31 55 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 PRINTS PR00990 Ribokinase signature 211 222 2.7E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 PRINTS PR00990 Ribokinase signature 26 45 2.7E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 PRINTS PR00990 Ribokinase signature 178 193 2.7E-5 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 SUPERFAMILY SSF53613 2 301 9.82E-73 T 23-10-2018 IPR029056 Ribokinase-like A3L14_09120 8d2972478af43e21da93a64aaf71c84b 316 Pfam PF00294 pfkB family carbohydrate kinase 2 293 4.9E-56 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L14_07275 795baf6c5fd0ceef67b56ff496535d3d 292 Gene3D G3DSA:3.40.50.970 63 219 2.7E-26 T 23-10-2018 A3L14_07275 795baf6c5fd0ceef67b56ff496535d3d 292 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 59 202 3.4E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_07275 795baf6c5fd0ceef67b56ff496535d3d 292 SUPERFAMILY SSF52518 18 266 9.56E-80 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_07275 795baf6c5fd0ceef67b56ff496535d3d 292 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 206 266 6.8E-26 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal A3L14_07275 795baf6c5fd0ceef67b56ff496535d3d 292 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 21 279 1.0E-109 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 43 7.1E-8 T 23-10-2018 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 Gene3D G3DSA:1.10.10.10 61 150 1.6E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 SUPERFAMILY SSF46785 68 146 2.24E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 Pfam PF01022 Bacterial regulatory protein, arsR family 76 120 3.3E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 Gene3D G3DSA:1.10.10.10 1 60 1.1E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 SMART SM00418 68 148 3.0E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 2.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 2.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_10440 ffe43f5a5f75e6d06ba4cab9438ee486 169 SUPERFAMILY SSF46785 4 58 8.19E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 Gene3D G3DSA:3.40.50.920 253 391 4.2E-40 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 SUPERFAMILY SSF52922 254 369 6.54E-33 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 6.8E-30 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 Gene3D G3DSA:3.40.50.970 2 252 1.1E-103 T 23-10-2018 A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 SUPERFAMILY SSF52518 4 251 7.2E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_10600 b08acb8add369758cf78d04bbfcdd91c 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 239 9.6E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_08205 003a64b558e998f6f98f8d27c7199297 196 SUPERFAMILY SSF52402 2 156 6.28E-40 T 23-10-2018 A3L14_08205 003a64b558e998f6f98f8d27c7199297 196 Gene3D G3DSA:3.40.50.620 1 195 4.6E-54 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_08205 003a64b558e998f6f98f8d27c7199297 196 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 188 4.9E-58 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L14_06385 de6d8787dc673b63527d13687adcad91 98 SUPERFAMILY SSF46785 7 92 2.52E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_06385 de6d8787dc673b63527d13687adcad91 98 Gene3D G3DSA:1.10.10.10 5 96 9.1E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06385 de6d8787dc673b63527d13687adcad91 98 Pfam PF12840 Helix-turn-helix domain 11 64 9.2E-14 T 23-10-2018 A3L14_06385 de6d8787dc673b63527d13687adcad91 98 SMART SM00418 10 91 4.4E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_02955 b1a96dcb063fad3f2d288311053153a8 151 Pfam PF01877 RNA binding 8 131 2.3E-38 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L14_02955 b1a96dcb063fad3f2d288311053153a8 151 SUPERFAMILY SSF55282 7 149 3.24E-41 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02955 b1a96dcb063fad3f2d288311053153a8 151 Gene3D G3DSA:3.30.1440.10 3 149 1.4E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 SMART SM00382 98 286 2.4E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 SMART SM00382 363 531 3.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Gene3D G3DSA:3.40.50.300 1 326 1.4E-102 T 23-10-2018 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Gene3D G3DSA:3.40.50.300 327 589 1.8E-66 T 23-10-2018 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Pfam PF00037 4Fe-4S binding domain 44 67 4.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Pfam PF00005 ABC transporter 96 238 2.6E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 SUPERFAMILY SSF52540 339 529 5.33E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 SUPERFAMILY SSF54862 4 126 7.15E-24 T 23-10-2018 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 4.1E-12 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 SUPERFAMILY SSF52540 96 285 3.58E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 Pfam PF00005 ABC transporter 360 482 5.4E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 48 72 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 134 150 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 20 35 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 75 95 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 150 176 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_06355 75d442803e323a9ac8bd2303762928cc 591 PRINTS PR01868 ABC transporter family E signature 103 128 1.3E-62 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 Gene3D G3DSA:1.10.443.10 90 280 1.8E-75 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 SUPERFAMILY SSF56349 3 269 2.06E-63 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 3 273 42.467 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 Pfam PF00589 Phage integrase family 98 261 6.6E-49 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 Gene3D G3DSA:1.10.150.130 2 89 8.1E-22 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A3L14_08240 7a380258132b78201d3f7fb8d8a888b8 280 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 77 1.2E-9 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 Gene3D G3DSA:3.40.800.20 5 311 4.1E-78 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 6.5E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 PRINTS PR01270 Histone deacetylase superfamily signature 125 148 6.5E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 PRINTS PR01270 Histone deacetylase superfamily signature 241 251 6.5E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 SUPERFAMILY SSF52768 4 335 3.69E-86 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L14_09530 3643d7bdba3ce30a87f1fc086356974a 336 Pfam PF00850 Histone deacetylase domain 20 290 2.4E-63 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 Pfam PF01163 RIO1 family 65 246 9.7E-54 T 23-10-2018 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 SMART SM00090 23 257 4.8E-119 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 SUPERFAMILY SSF56112 47 231 2.99E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 Gene3D G3DSA:3.30.200.20 51 151 8.7E-13 T 23-10-2018 A3L14_06570 4832d8d23419ae04e7f45f072cb55c83 258 Gene3D G3DSA:1.10.510.10 156 257 2.3E-25 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00305 1409 1454 1.2E-12 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF55608 1233 1316 1.59E-11 T 23-10-2018 IPR027434 Homing endonuclease A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00436 796 883 2.4E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1429 1449 1.1E-4 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:1.10.290.10 924 960 8.2E-9 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF01751 Toprim domain 644 805 3.1E-28 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:2.70.20.10 1542 1604 1.6E-57 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF00270 DEAD/DEAH box helicase 88 221 1.2E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:1.10.290.10 1447 1541 1.6E-57 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF51294 961 1448 8.44E-29 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:2.170.16.10 962 1098 1.0E-14 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF56712 637 961 4.19E-77 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00493 642 795 6.3E-45 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF52540 326 625 1.26E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1621 1635 1.0E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 1.0E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 1.0E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1446 1455 1.0E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1527 1543 1.0E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:3.40.50.140 630 819 3.3E-30 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 961 1035 4.6E-11 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:1.10.460.10 823 891 1.1E-20 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:1.10.460.10 1605 1703 1.6E-57 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Hamap MF_01125 Reverse gyrase [rgy]. 1 1708 57.019 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF14528 LAGLIDADG-like domain 1240 1316 9.7E-10 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:3.10.28.10 1153 1309 1.8E-14 T 23-10-2018 IPR027434 Homing endonuclease A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF52540 34 243 1.48E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1705 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SUPERFAMILY SSF56712 1447 1707 3.01E-58 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00487 81 331 1.1E-21 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00379 Intein signature 1157 1169 4.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00379 Intein signature 1274 1289 4.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00379 Intein signature 1443 1452 4.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00379 Intein signature 1022 1035 4.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 PRINTS PR00379 Intein signature 1240 1252 4.3E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:2.70.20.10 909 923 8.2E-9 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF01131 DNA topoisomerase 1448 1697 6.6E-50 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF01131 DNA topoisomerase 820 960 4.1E-24 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00437 916 1660 1.1E-92 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 SMART SM00306 959 1059 3.0E-21 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Pfam PF14890 Intein splicing domain 968 1448 6.2E-35 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:3.40.50.300 65 319 6.5E-83 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:3.40.50.300 320 498 2.2E-33 T 23-10-2018 A3L14_03810 779d1d5d63ad56942521959a8278dbd9 1709 Gene3D G3DSA:3.40.50.300 546 629 9.0E-14 T 23-10-2018 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 Gene3D G3DSA:3.40.50.720 7 327 5.3E-96 T 23-10-2018 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 PIRSF PIRSF036497 1 335 2.4E-89 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 SUPERFAMILY SSF51735 3 177 7.46E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 SUPERFAMILY SSF55347 156 314 1.77E-39 T 23-10-2018 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 Gene3D G3DSA:3.30.360.10 167 310 5.3E-96 T 23-10-2018 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 Pfam PF00742 Homoserine dehydrogenase 156 327 3.4E-51 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L14_02235 3b909d1f6eed353d7a728d372cefafde 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 5.8E-10 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A3L14_10195 319aac926c26fb51dccfbf114398a665 167 SUPERFAMILY SSF55729 14 160 6.71E-39 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_10195 319aac926c26fb51dccfbf114398a665 167 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 3.4E-28 T 23-10-2018 IPR000182 GNAT domain A3L14_10195 319aac926c26fb51dccfbf114398a665 167 Gene3D G3DSA:3.40.630.30 16 163 3.2E-48 T 23-10-2018 A3L14_10195 319aac926c26fb51dccfbf114398a665 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 5.5E-34 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A3L14_10200 49cc0f171843faadb71d086e51edfc7e 588 SUPERFAMILY SSF52540 148 542 1.54E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10200 49cc0f171843faadb71d086e51edfc7e 588 Gene3D G3DSA:3.40.50.300 138 292 8.4E-20 T 23-10-2018 A3L14_10200 49cc0f171843faadb71d086e51edfc7e 588 Pfam PF09378 HAS barrel domain 11 112 8.6E-21 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L14_10200 49cc0f171843faadb71d086e51edfc7e 588 Pfam PF01935 Domain of unknown function DUF87 152 377 9.8E-51 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L14_01955 b132674dd3928f5f2543a13fc8bafdd5 377 Pfam PF04123 Domain of unknown function (DUF373) 6 353 2.8E-98 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 Gene3D G3DSA:1.10.1330.10 444 501 8.1E-9 T 23-10-2018 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 PRINTS PR00113 Alkaline phosphatase signature 230 259 5.5E-37 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 PRINTS PR00113 Alkaline phosphatase signature 37 57 5.5E-37 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 PRINTS PR00113 Alkaline phosphatase signature 167 177 5.5E-37 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 PRINTS PR00113 Alkaline phosphatase signature 123 143 5.5E-37 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 ProSitePatterns PS00123 Alkaline phosphatase active site. 83 91 - T 23-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 SMART SM00098 38 432 1.4E-91 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 SUPERFAMILY SSF53649 33 429 7.33E-118 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 Gene3D G3DSA:3.40.720.10 41 421 4.5E-126 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 ProSitePatterns PS00018 EF-hand calcium-binding domain. 482 494 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 Gene3D G3DSA:1.10.60.40 306 391 4.5E-126 T 23-10-2018 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 Pfam PF00245 Alkaline phosphatase 38 427 2.1E-89 T 23-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 SUPERFAMILY SSF63446 445 499 3.01E-9 T 23-10-2018 IPR036439 Dockerin domain superfamily GO:0000272 A3L14_01260 54335ffabe73ecaf4b97b5de17de3189 501 ProSitePatterns PS00448 Clostridium cellulosome enzymes repeated domain signature. 449 468 - T 23-10-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 Pfam PF00270 DEAD/DEAH box helicase 25 191 6.0E-47 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 SUPERFAMILY SSF52540 71 354 1.29E-74 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 Pfam PF00271 Helicase conserved C-terminal domain 241 333 7.5E-26 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 SMART SM00490 252 333 1.6E-32 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 Gene3D G3DSA:3.40.50.300 1 207 4.8E-76 T 23-10-2018 A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 SMART SM00487 20 223 8.1E-64 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_08305 3c745631d05712908f4124dd0bf7c642 411 Gene3D G3DSA:3.40.50.300 211 395 6.3E-51 T 23-10-2018 A3L14_02765 ed147bda25fe337ccaadb6edc83a02e8 238 SUPERFAMILY SSF47413 15 62 7.95E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_02765 ed147bda25fe337ccaadb6edc83a02e8 238 SUPERFAMILY SSF53271 75 237 1.57E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_02765 ed147bda25fe337ccaadb6edc83a02e8 238 Gene3D G3DSA:3.40.50.2020 64 238 1.1E-39 T 23-10-2018 A3L14_02765 ed147bda25fe337ccaadb6edc83a02e8 238 Pfam PF00156 Phosphoribosyl transferase domain 101 214 6.0E-12 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_02765 ed147bda25fe337ccaadb6edc83a02e8 238 Pfam PF01381 Helix-turn-helix 17 62 1.3E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_02430 3d089f128e85924659886e574796c59f 384 PIRSF PIRSF000524 17 384 3.3E-101 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A3L14_02430 3d089f128e85924659886e574796c59f 384 Pfam PF00266 Aminotransferase class-V 45 369 2.8E-43 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L14_02430 3d089f128e85924659886e574796c59f 384 SUPERFAMILY SSF53383 22 383 1.63E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_02430 3d089f128e85924659886e574796c59f 384 Gene3D G3DSA:3.90.1150.10 25 379 1.5E-136 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_02430 3d089f128e85924659886e574796c59f 384 Gene3D G3DSA:3.40.640.10 35 280 1.5E-136 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_02430 3d089f128e85924659886e574796c59f 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 PIRSF PIRSF001338 1 143 8.2E-60 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 142 4.2E-56 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 25.852 T 23-10-2018 IPR033747 Class I PurE A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 Gene3D G3DSA:3.40.50.7700 2 143 4.0E-62 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 Pfam PF00731 AIR carboxylase 2 142 2.1E-57 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 SMART SM01001 1 143 1.6E-73 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L14_01390 e829f2a75c3201e04f86d287253bcf65 143 SUPERFAMILY SSF52255 1 142 8.37E-54 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L14_00225 e123ec10d2a9a7d1824e45d9d140a254 65 SUPERFAMILY SSF141694 1 58 3.4E-14 T 23-10-2018 A3L14_00225 e123ec10d2a9a7d1824e45d9d140a254 65 Gene3D G3DSA:4.10.1150.10 1 65 7.1E-12 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L14_00225 e123ec10d2a9a7d1824e45d9d140a254 65 Pfam PF01954 Protein of unknown function DUF104 1 57 5.3E-16 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_08680 7b5dc32200b0dce9135fe4a46ff31cd6 131 Pfam PF01850 PIN domain 3 111 7.4E-11 T 23-10-2018 IPR002716 PIN domain A3L14_08680 7b5dc32200b0dce9135fe4a46ff31cd6 131 Gene3D G3DSA:3.40.50.1010 1 121 1.6E-12 T 23-10-2018 A3L14_08680 7b5dc32200b0dce9135fe4a46ff31cd6 131 SUPERFAMILY SSF88723 1 116 4.21E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_07505 69dfbedf168d7ffac52f30dbaa5aee06 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 4.0E-33 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_07505 69dfbedf168d7ffac52f30dbaa5aee06 281 Gene3D G3DSA:3.20.20.70 2 279 1.3E-83 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_07505 69dfbedf168d7ffac52f30dbaa5aee06 281 SUPERFAMILY SSF51569 8 266 2.78E-68 T 23-10-2018 A3L14_07505 69dfbedf168d7ffac52f30dbaa5aee06 281 SMART SM01133 23 251 8.5E-43 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_07505 69dfbedf168d7ffac52f30dbaa5aee06 281 PIRSF PIRSF038992 4 280 1.3E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_04270 726621e4449587ba128415443330d7d2 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 SMART SM00870 94 417 5.6E-154 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 PIRSF PIRSF001220 90 428 1.9E-112 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 SUPERFAMILY SSF141300 4 75 2.62E-18 T 23-10-2018 IPR037222 GatD, N-terminal A3L14_04270 726621e4449587ba128415443330d7d2 439 Gene3D G3DSA:3.40.50.1170 81 301 5.5E-87 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 SUPERFAMILY SSF53774 87 436 3.93E-120 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 49.125 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L14_04270 726621e4449587ba128415443330d7d2 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L14_04270 726621e4449587ba128415443330d7d2 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 8.4E-196 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L14_04270 726621e4449587ba128415443330d7d2 439 Gene3D G3DSA:2.30.30.520 2 79 3.5E-21 T 23-10-2018 IPR037222 GatD, N-terminal A3L14_04270 726621e4449587ba128415443330d7d2 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 1.4E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 1.4E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 1.4E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 6.5E-148 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 Gene3D G3DSA:3.40.50.40 302 438 5.4E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 Pfam PF00710 Asparaginase, N-terminal 95 287 5.8E-63 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L14_04270 726621e4449587ba128415443330d7d2 439 PIRSF PIRSF500175 13 437 2.6E-190 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L14_03345 bc9287b997df8291c2adf529a62be43e 67 Pfam PF02597 ThiS family 10 67 1.1E-10 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L14_03345 bc9287b997df8291c2adf529a62be43e 67 Gene3D G3DSA:3.10.20.30 1 67 1.7E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_03345 bc9287b997df8291c2adf529a62be43e 67 SUPERFAMILY SSF54285 4 67 3.63E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L14_08635 5ba094f8d8bd31fbbe0fbe339f4547f8 235 SUPERFAMILY SSF56300 1 235 7.75E-64 T 23-10-2018 A3L14_08635 5ba094f8d8bd31fbbe0fbe339f4547f8 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 1.3E-29 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L14_08635 5ba094f8d8bd31fbbe0fbe339f4547f8 235 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 195 9.3E-17 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L14_08635 5ba094f8d8bd31fbbe0fbe339f4547f8 235 Gene3D G3DSA:3.60.21.10 2 235 2.0E-68 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_08635 5ba094f8d8bd31fbbe0fbe339f4547f8 235 PIRSF PIRSF000883 1 235 1.1E-70 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L14_09755 a7216982878da22bdd972c5ffa887e83 422 Pfam PF03577 Peptidase family C69 78 217 1.2E-9 T 23-10-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 A3L14_09755 a7216982878da22bdd972c5ffa887e83 422 Gene3D G3DSA:3.60.60.10 2 301 2.5E-22 T 23-10-2018 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 SUPERFAMILY SSF52954 332 436 1.66E-21 T 23-10-2018 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 SUPERFAMILY SSF55681 7 332 2.49E-86 T 23-10-2018 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 384 26.238 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Pfam PF03129 Anticodon binding domain 342 431 2.8E-18 T 23-10-2018 IPR004154 Anticodon-binding A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 PIRSF PIRSF001549 1 434 7.1E-138 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 327 7.7E-86 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Gene3D G3DSA:3.40.50.800 339 434 2.5E-23 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 433 31.004 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 423 8.9E-126 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Gene3D G3DSA:3.30.930.10 1 329 2.4E-109 T 23-10-2018 A3L14_00570 ec760ef096e01f6c1d1ddb434e394e92 437 Pfam PF13393 Histidyl-tRNA synthetase 10 324 1.4E-66 T 23-10-2018 A3L14_08255 38e36fbf190f8de9030f93e089427ca1 451 Pfam PF13173 AAA domain 26 148 2.4E-9 T 23-10-2018 A3L14_08255 38e36fbf190f8de9030f93e089427ca1 451 Gene3D G3DSA:3.40.50.300 1 167 1.2E-23 T 23-10-2018 A3L14_08255 38e36fbf190f8de9030f93e089427ca1 451 SUPERFAMILY SSF46785 242 356 1.2E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08255 38e36fbf190f8de9030f93e089427ca1 451 Pfam PF03008 Archaea bacterial proteins of unknown function 312 400 3.1E-17 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_08255 38e36fbf190f8de9030f93e089427ca1 451 SUPERFAMILY SSF52540 1 204 7.64E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Gene3D G3DSA:3.30.950.30 1 113 1.1E-28 T 23-10-2018 IPR038461 Schlafen, AAA domain superfamily A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 SUPERFAMILY SSF46785 371 441 5.54E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Gene3D G3DSA:3.30.565.60 206 366 7.6E-47 T 23-10-2018 IPR038475 RecG, C-terminal domain superfamily A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 280 366 3.7E-21 T 23-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Pfam PF08220 DeoR-like helix-turn-helix domain 387 430 8.1E-5 T 23-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Pfam PF04326 Putative DNA-binding domain 11 113 4.9E-16 T 23-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 A3L14_01145 9576af80d93e304c5eabbc3a9e0ec34c 447 Gene3D G3DSA:1.10.10.10 367 444 7.3E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09520 46c122473db3bc98d42da3d75981a170 646 SUPERFAMILY SSF52518 380 601 1.5E-32 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Gene3D G3DSA:3.40.50.970 390 568 2.4E-21 T 23-10-2018 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 SUPERFAMILY SSF52518 14 249 7.02E-58 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 562 5.3E-29 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Pfam PF12838 4Fe-4S dicluster domain 591 637 2.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_09520 46c122473db3bc98d42da3d75981a170 646 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 638 3.7E-267 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Gene3D G3DSA:3.40.50.970 5 195 9.3E-54 T 23-10-2018 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 PIRSF PIRSF006439 5 645 1.5E-259 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 7.2E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 623 634 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_09520 46c122473db3bc98d42da3d75981a170 646 SUPERFAMILY SSF52922 249 355 4.01E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 SUPERFAMILY SSF54862 585 643 3.32E-13 T 23-10-2018 A3L14_09520 46c122473db3bc98d42da3d75981a170 646 Gene3D G3DSA:3.30.70.20 584 640 1.0E-10 T 23-10-2018 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Gene3D G3DSA:2.170.8.10 62 395 1.1E-148 T 23-10-2018 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 26 236 5.3E-56 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 241 603 2.5E-107 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Gene3D G3DSA:3.90.228.20 244 602 1.1E-148 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 265 273 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 SUPERFAMILY SSF68923 8 240 6.28E-61 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 SUPERFAMILY SSF53795 241 603 5.72E-108 T 23-10-2018 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 15 604 36.116 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 Gene3D G3DSA:3.40.449.10 24 243 1.1E-148 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L14_03550 e082eb575b7ae91271bc7eaca15c995d 622 PIRSF PIRSF001348 2 607 9.2E-209 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 TIGRFAM TIGR01370 TIGR01370: extracellular protein 74 366 2.1E-114 T 23-10-2018 IPR016063 Extracellular protein A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 SUPERFAMILY SSF51445 100 354 1.05E-42 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 Gene3D G3DSA:3.20.20.70 83 376 3.2E-108 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 242 254 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 316 326 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 189 207 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 261 275 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 101 114 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 115 128 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 343 355 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 170 187 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 207 226 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 147 166 1.8E-67 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A3L14_06075 13d919fa2bc9d0409e97d594449ddb89 376 Pfam PF03537 Glycoside-hydrolase family GH114 101 330 2.0E-28 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 SUPERFAMILY SSF56112 134 388 1.34E-70 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 255 267 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 Gene3D G3DSA:1.10.510.10 124 408 1.9E-66 T 23-10-2018 A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 Pfam PF00069 Protein kinase domain 145 385 5.8E-48 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 SMART SM00220 145 394 2.9E-59 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L14_07035 ce801b8a599c25be4aec468cc788e9a0 492 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 151 173 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A3L14_00680 d245648e01493850a5fea1cbfc4143e4 305 Gene3D G3DSA:1.20.1640.10 117 302 1.7E-14 T 23-10-2018 A3L14_00680 d245648e01493850a5fea1cbfc4143e4 305 SUPERFAMILY SSF82866 120 291 7.46E-24 T 23-10-2018 A3L14_00680 d245648e01493850a5fea1cbfc4143e4 305 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 300 25.773 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A3L14_00680 d245648e01493850a5fea1cbfc4143e4 305 Pfam PF02355 Protein export membrane protein 127 296 4.3E-30 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 Pfam PF00281 Ribosomal protein L5 16 68 1.9E-20 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 SUPERFAMILY SSF55282 15 179 1.08E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.729 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 PIRSF PIRSF002161 2 180 3.1E-56 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 3.7E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02545 d69d5391dd9b72aebedfc8ae923b8bcb 183 Gene3D G3DSA:3.30.1440.10 10 182 1.1E-72 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 SUPERFAMILY SSF52374 164 372 7.11E-77 T 23-10-2018 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 Gene3D G3DSA:3.10.400.10 1 159 4.6E-47 T 23-10-2018 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 Pfam PF01747 ATP-sulfurylase 164 372 2.0E-85 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 SUPERFAMILY SSF88697 4 161 5.47E-48 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 Pfam PF14306 PUA-like domain 4 156 3.7E-50 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 Gene3D G3DSA:3.40.50.620 164 373 3.9E-89 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.189 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A3L14_01195 71a00c7982840f3cd7d03d8a28e48920 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 6.2E-118 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L14_01010 93b8524cf471353147e42211d90f1414 73 Pfam PF02597 ThiS family 13 73 1.2E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L14_01010 93b8524cf471353147e42211d90f1414 73 Gene3D G3DSA:3.10.20.30 1 73 1.3E-12 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_01010 93b8524cf471353147e42211d90f1414 73 SUPERFAMILY SSF54285 14 73 3.49E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 SUPERFAMILY SSF109728 82 155 7.06E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 Gene3D G3DSA:3.30.1250.10 8 87 4.2E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 Pfam PF09377 SBDS protein C-terminal domain 101 210 4.8E-17 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 1.5E-91 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 SUPERFAMILY SSF54980 157 228 2.88E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 1.2E-25 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 SUPERFAMILY SSF89895 4 87 7.72E-26 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 Gene3D G3DSA:3.30.70.240 163 235 7.2E-29 T 23-10-2018 A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 Gene3D G3DSA:1.10.10.900 88 162 3.2E-30 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L14_02185 3cb2577a6d1b619d75139a5bed06a946 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site A3L14_01535 f1b5029795410144b27d86cbfbd6b7ec 177 Pfam PF04019 Protein of unknown function (DUF359) 50 171 4.1E-39 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L14_01535 f1b5029795410144b27d86cbfbd6b7ec 177 PIRSF PIRSF006533 1 175 1.1E-54 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L14_01535 f1b5029795410144b27d86cbfbd6b7ec 177 Hamap MF_00590 UPF0218 protein . 6 173 29.27 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 6.1E-46 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 440 5.9E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Gene3D G3DSA:3.40.120.10 1 152 1.9E-62 T 23-10-2018 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Gene3D G3DSA:3.30.310.50 371 455 6.7E-29 T 23-10-2018 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 SUPERFAMILY SSF55957 358 455 3.01E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 SUPERFAMILY SSF53738 155 259 4.32E-30 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Gene3D G3DSA:3.40.120.10 257 365 1.9E-76 T 23-10-2018 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 SUPERFAMILY SSF53738 261 367 1.14E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 445 3.9E-176 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 1.9E-29 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 SUPERFAMILY SSF53738 3 180 4.32E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Gene3D G3DSA:3.40.120.10 169 358 1.9E-76 T 23-10-2018 A3L14_03265 26ff62b621a8d663ab8286efe321766a 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 3.2E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00775 13187fded3e8d9bd54213539d7448050 377 SMART SM00729 56 253 1.3E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_00775 13187fded3e8d9bd54213539d7448050 377 SUPERFAMILY SSF102114 60 261 1.31E-30 T 23-10-2018 A3L14_00775 13187fded3e8d9bd54213539d7448050 377 Pfam PF04055 Radical SAM superfamily 61 210 2.3E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_00775 13187fded3e8d9bd54213539d7448050 377 Gene3D G3DSA:3.20.20.70 51 305 5.1E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01845 9509c3b84bae35fcf1fcb32abb7ba7c9 207 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 178 7.1E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_01845 9509c3b84bae35fcf1fcb32abb7ba7c9 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.439 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A3L14_01845 9509c3b84bae35fcf1fcb32abb7ba7c9 207 Pfam PF01926 50S ribosome-binding GTPase 2 129 3.6E-18 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_01845 9509c3b84bae35fcf1fcb32abb7ba7c9 207 SUPERFAMILY SSF52540 2 182 1.49E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01845 9509c3b84bae35fcf1fcb32abb7ba7c9 207 Gene3D G3DSA:3.40.50.300 1 186 9.3E-52 T 23-10-2018 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 SUPERFAMILY SSF56235 5 202 1.14E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_03035 604a864e9485397b97bf7862aba484ba 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 2.8E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 34.788 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 Gene3D G3DSA:3.60.20.10 3 203 3.5E-68 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_03035 604a864e9485397b97bf7862aba484ba 203 Pfam PF00227 Proteasome subunit 6 185 8.7E-53 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 PRINTS PR00141 Proteasome component signature 15 30 1.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 PRINTS PR00141 Proteasome component signature 146 157 1.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 PRINTS PR00141 Proteasome component signature 135 146 1.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03035 604a864e9485397b97bf7862aba484ba 203 PRINTS PR00141 Proteasome component signature 171 182 1.2E-8 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_03450 055ec7cfed60b3db470024d7a21846f5 501 Pfam PF02347 Glycine cleavage system P-protein 30 309 6.3E-11 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L14_03450 055ec7cfed60b3db470024d7a21846f5 501 Gene3D G3DSA:3.90.1150.10 339 474 8.8E-45 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_03450 055ec7cfed60b3db470024d7a21846f5 501 Gene3D G3DSA:3.40.640.10 86 317 2.8E-61 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_03450 055ec7cfed60b3db470024d7a21846f5 501 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 489 61.427 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A3L14_03450 055ec7cfed60b3db470024d7a21846f5 501 SUPERFAMILY SSF53383 12 487 4.35E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Gene3D G3DSA:3.10.580.10 1 122 5.5E-38 T 23-10-2018 A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SUPERFAMILY SSF54631 125 278 2.42E-31 T 23-10-2018 A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Pfam PF00571 CBS domain 224 279 8.4E-13 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Pfam PF00571 CBS domain 67 116 3.4E-11 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Pfam PF00571 CBS domain 3 55 2.2E-7 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Pfam PF00571 CBS domain 142 181 9.2E-5 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 Gene3D G3DSA:3.10.580.10 123 281 1.2E-36 T 23-10-2018 A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SMART SM00116 10 59 7.0E-4 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SMART SM00116 231 279 3.2E-10 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SMART SM00116 136 184 3.8 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SMART SM00116 70 118 8.0E-9 T 23-10-2018 IPR000644 CBS domain A3L14_02240 184615e31b20be22f0cf82be4513a2ff 281 SUPERFAMILY SSF54631 1 118 1.24E-26 T 23-10-2018 A3L14_01680 9f31beaf5b0f4422212c76df8c42df43 266 Pfam PF13630 SdpI/YhfL protein family 29 89 5.0E-12 T 23-10-2018 IPR025962 SdpI/YhfL protein family A3L14_01680 9f31beaf5b0f4422212c76df8c42df43 266 Pfam PF07853 Protein of unknown function (DUF1648) 132 176 2.7E-13 T 23-10-2018 IPR012867 Domain of unknown function DUF1648 A3L14_07625 890b35c8d39bde1966b2fc884a898e7b 139 Gene3D G3DSA:3.30.1330.80 1 138 3.7E-48 T 23-10-2018 A3L14_07625 890b35c8d39bde1966b2fc884a898e7b 139 PIRSF PIRSF016702 1 139 2.0E-45 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A3L14_07625 890b35c8d39bde1966b2fc884a898e7b 139 SUPERFAMILY SSF117856 4 129 7.06E-36 T 23-10-2018 A3L14_07625 890b35c8d39bde1966b2fc884a898e7b 139 Pfam PF03479 Domain of unknown function (DUF296) 8 118 1.8E-19 T 23-10-2018 IPR005175 PPC domain A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 Pfam PF12327 FtsZ family, C-terminal domain 253 347 2.5E-24 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 Gene3D G3DSA:3.40.50.1440 35 347 4.7E-99 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 5.5E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 SUPERFAMILY SSF55307 238 352 6.18E-35 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 33 356 1.8E-112 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 SMART SM00864 37 236 3.5E-85 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 SMART SM00865 238 355 2.4E-38 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 SUPERFAMILY SSF52490 36 239 5.89E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 383 33.614 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 PRINTS PR00423 Cell division protein FtsZ signature 122 142 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 PRINTS PR00423 Cell division protein FtsZ signature 220 242 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 PRINTS PR00423 Cell division protein FtsZ signature 243 264 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_09280 ceea8df71df85a19a42ee6bd0eb3b8e7 414 PRINTS PR00423 Cell division protein FtsZ signature 158 179 7.2E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_08805 a70838b8abfdd4ac93050a9e59031ca4 399 SUPERFAMILY SSF111283 30 379 9.02E-52 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_08805 a70838b8abfdd4ac93050a9e59031ca4 399 Pfam PF01523 Putative modulator of DNA gyrase 26 265 3.8E-19 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 420 7.6E-39 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 SUPERFAMILY SSF46589 1 115 1.67E-27 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 4.9E-162 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.699 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 Gene3D G3DSA:1.10.287.40 1 107 6.1E-34 T 23-10-2018 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 SUPERFAMILY SSF55681 154 445 4.73E-88 T 23-10-2018 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 3.4E-27 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 PIRSF PIRSF001529 1 447 1.3E-154 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L14_08610 af103d0b7d0257901e01423faedd20e1 455 Gene3D G3DSA:3.30.930.10 108 455 8.5E-136 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 SUPERFAMILY SSF51971 187 429 6.47E-74 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 SUPERFAMILY SSF53706 703 833 1.01E-12 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 SUPERFAMILY SSF46548 96 199 2.25E-21 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 189 482 2.6E-43 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 72 2.5E-10 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Gene3D G3DSA:3.30.70.20 612 694 5.8E-13 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 1.8E-21 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 PRINTS PR00419 Adrenodoxin reductase family signature 255 265 1.8E-21 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 PRINTS PR00419 Adrenodoxin reductase family signature 190 212 1.8E-21 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 PRINTS PR00419 Adrenodoxin reductase family signature 354 367 1.8E-21 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 PRINTS PR00419 Adrenodoxin reductase family signature 321 335 1.8E-21 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Gene3D G3DSA:3.50.50.60 316 515 8.4E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Gene3D G3DSA:3.50.50.60 186 314 1.1E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 SUPERFAMILY SSF54862 580 694 1.97E-17 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 SUPERFAMILY SSF54292 1 97 5.38E-24 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Gene3D G3DSA:3.10.20.740 1 115 1.8E-24 T 23-10-2018 A3L14_02405 dddbc307521bf7a69c0e94bcbdc930ff 952 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 98 176 1.7E-18 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L14_02190 4eab3d01894735832ed695915442488e 256 Gene3D G3DSA:3.30.1370.10 149 236 7.7E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_02190 4eab3d01894735832ed695915442488e 256 Pfam PF15985 KH domain 149 194 2.7E-8 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L14_02190 4eab3d01894735832ed695915442488e 256 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 235 39.957 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A3L14_02190 4eab3d01894735832ed695915442488e 256 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 2.1E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02190 4eab3d01894735832ed695915442488e 256 Gene3D G3DSA:2.40.50.140 58 142 4.9E-20 T 23-10-2018 A3L14_02190 4eab3d01894735832ed695915442488e 256 SMART SM00316 63 137 1.6E-6 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L14_02190 4eab3d01894735832ed695915442488e 256 SUPERFAMILY SSF110324 3 58 1.07E-13 T 23-10-2018 A3L14_02190 4eab3d01894735832ed695915442488e 256 SMART SM00322 146 211 1.2E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_02190 4eab3d01894735832ed695915442488e 256 SUPERFAMILY SSF54791 148 226 5.31E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_02190 4eab3d01894735832ed695915442488e 256 Gene3D G3DSA:2.40.50.100 1 57 2.6E-21 T 23-10-2018 A3L14_02190 4eab3d01894735832ed695915442488e 256 SUPERFAMILY SSF50249 59 152 4.76E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 SMART SM00359 88 163 6.7E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 SUPERFAMILY SSF88697 88 169 1.49E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 PIRSF PIRSF005067 1 172 7.7E-44 T 23-10-2018 IPR016437 MCT-1/Tma20 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 2.5E-7 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 Pfam PF01472 PUA domain 89 161 2.3E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 5.9E-30 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 Gene3D G3DSA:3.10.450.120 1 78 7.5E-37 T 23-10-2018 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 Gene3D G3DSA:2.30.130.10 79 171 4.5E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_09260 cf0a836b7e1ce9e2040430a648092c06 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 3.0E-57 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A3L14_05845 cc4546cbbac29dc8f805f5c011c7f50f 364 Pfam PF02915 Rubrerythrin 13 139 4.5E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_05845 cc4546cbbac29dc8f805f5c011c7f50f 364 Gene3D G3DSA:1.20.1260.10 10 143 1.7E-6 T 23-10-2018 IPR012347 Ferritin-like A3L14_05845 cc4546cbbac29dc8f805f5c011c7f50f 364 SUPERFAMILY SSF47240 4 141 3.83E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_05845 cc4546cbbac29dc8f805f5c011c7f50f 364 Pfam PF01988 VIT family 149 353 1.8E-46 T 23-10-2018 IPR008217 Ccc1 family A3L14_05300 9e8d1801c0df85f36a4bf3fc914b737b 115 PIRSF PIRSF006113 1 115 1.2E-35 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L14_05300 9e8d1801c0df85f36a4bf3fc914b737b 115 Gene3D G3DSA:3.30.479.10 1 115 2.2E-39 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L14_05300 9e8d1801c0df85f36a4bf3fc914b737b 115 SUPERFAMILY SSF55620 4 114 1.22E-32 T 23-10-2018 A3L14_05300 9e8d1801c0df85f36a4bf3fc914b737b 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 8.3E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L14_11215 13dabdf3e13399447e90a18db1045dbd 190 Pfam PF00717 Peptidase S24-like 37 87 4.7E-5 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L14_11215 13dabdf3e13399447e90a18db1045dbd 190 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 151 3.6E-22 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_11215 13dabdf3e13399447e90a18db1045dbd 190 SUPERFAMILY SSF51306 29 126 1.78E-8 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 SMART SM00488 6 257 5.9E-79 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 SMART SM00491 465 607 8.6E-46 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Pfam PF13307 Helicase C-terminal domain 448 620 3.8E-37 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Pfam PF06777 Helical and beta-bridge domain 243 434 2.8E-66 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Gene3D G3DSA:3.40.50.300 23 402 4.0E-115 T 23-10-2018 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Pfam PF06733 DEAD_2 67 238 1.9E-33 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 SMART SM00487 11 277 9.6E-9 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 357 631 2.4E-78 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 SUPERFAMILY SSF52540 28 601 4.18E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Gene3D G3DSA:1.10.30.20 98 174 4.0E-115 T 23-10-2018 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 SUPERFAMILY SSF52540 8 231 2.57E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Gene3D G3DSA:1.10.275.40 233 370 4.0E-115 T 23-10-2018 A3L14_08275 0f36d3a7d3294a6b91604bdaccd428df 639 Gene3D G3DSA:3.40.50.300 417 630 8.1E-42 T 23-10-2018 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 SUPERFAMILY SSF55681 223 495 5.84E-60 T 23-10-2018 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Gene3D G3DSA:3.30.930.10 238 499 9.0E-77 T 23-10-2018 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Pfam PF01409 tRNA synthetases class II core domain (F) 223 494 5.1E-82 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 496 37.201 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 SUPERFAMILY SSF46785 71 145 7.79E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Gene3D G3DSA:1.10.10.2310 19 221 1.2E-17 T 23-10-2018 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 188 495 1.5E-92 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Gene3D G3DSA:1.10.10.2330 74 137 1.2E-17 T 23-10-2018 A3L14_04225 60badaf0274d5fe5551502203f8ab30d 499 Gene3D G3DSA:1.10.10.2320 61 173 1.2E-17 T 23-10-2018 A3L14_05350 38db6f8b5ec379f1e333bd8200a69646 284 Gene3D G3DSA:3.40.50.970 68 271 5.0E-33 T 23-10-2018 A3L14_05350 38db6f8b5ec379f1e333bd8200a69646 284 SUPERFAMILY SSF52518 19 274 1.97E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_05350 38db6f8b5ec379f1e333bd8200a69646 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 1.8E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_08810 365d528f9a6c39a356c5e16bf3e9102c 444 Gene3D G3DSA:3.30.2290.10 3 193 6.1E-10 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_08810 365d528f9a6c39a356c5e16bf3e9102c 444 SUPERFAMILY SSF111283 4 438 1.31E-79 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_08810 365d528f9a6c39a356c5e16bf3e9102c 444 PIRSF PIRSF004919 1 443 5.6E-115 T 23-10-2018 IPR025502 TldD A3L14_08810 365d528f9a6c39a356c5e16bf3e9102c 444 Pfam PF01523 Putative modulator of DNA gyrase 17 299 7.6E-38 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_07235 4512df9a4024bbe2f2dd22446748d8b3 178 Pfam PF00881 Nitroreductase family 7 62 9.5E-16 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_07235 4512df9a4024bbe2f2dd22446748d8b3 178 Pfam PF00881 Nitroreductase family 63 150 4.6E-12 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_07235 4512df9a4024bbe2f2dd22446748d8b3 178 SUPERFAMILY SSF55469 1 171 5.37E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_07235 4512df9a4024bbe2f2dd22446748d8b3 178 Gene3D G3DSA:3.40.109.10 1 173 1.6E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Gene3D G3DSA:3.40.1190.20 210 477 2.7E-74 T 23-10-2018 IPR029056 Ribokinase-like A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 SUPERFAMILY SSF64153 4 225 8.63E-49 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.841 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 PIRSF PIRSF017184 2 479 8.8E-95 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 5.4E-33 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 213 474 6.6E-70 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 SUPERFAMILY SSF53613 213 474 3.47E-59 T 23-10-2018 IPR029056 Ribokinase-like A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 1.2E-43 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Gene3D G3DSA:3.40.50.10260 8 204 8.4E-42 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Pfam PF01256 Carbohydrate kinase 227 471 1.8E-50 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L14_00180 2871f3ec1c1bd571bb88a132c1606feb 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.291 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L14_00670 1f5727302b6f0f7d171eae41bbdacbf4 168 Gene3D G3DSA:2.30.130.10 95 166 1.6E-19 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_00670 1f5727302b6f0f7d171eae41bbdacbf4 168 Gene3D G3DSA:3.10.450.220 1 94 4.5E-46 T 23-10-2018 A3L14_00670 1f5727302b6f0f7d171eae41bbdacbf4 168 Pfam PF03657 Uncharacterised protein family (UPF0113) 6 166 5.3E-10 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A3L14_05710 49940eadf0c8f5302866fff167dffc84 1350 SUPERFAMILY SSF82866 1181 1343 2.09E-19 T 23-10-2018 A3L14_05710 49940eadf0c8f5302866fff167dffc84 1350 Pfam PF03176 MMPL family 751 973 2.4E-35 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L14_05710 49940eadf0c8f5302866fff167dffc84 1350 Pfam PF03176 MMPL family 1107 1343 4.8E-29 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L14_05710 49940eadf0c8f5302866fff167dffc84 1350 SUPERFAMILY SSF82866 762 963 3.53E-25 T 23-10-2018 A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 TIGRFAM TIGR00552 nadE: NAD+ synthetase 9 248 2.8E-82 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 Gene3D G3DSA:3.40.50.620 7 253 6.1E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 SUPERFAMILY SSF52402 4 249 2.87E-76 T 23-10-2018 A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 Pfam PF02540 NAD synthase 10 248 3.5E-85 T 23-10-2018 IPR022310 NAD/GMP synthase A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 217 226 - T 23-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A3L14_00820 98680a3b490ed21af271c78c10da4c4e 253 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 251 52.209 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A3L14_08180 b936527e5ccef8385b8664698a67b27d 233 Gene3D G3DSA:3.40.50.11570 8 220 4.3E-46 T 23-10-2018 A3L14_08180 b936527e5ccef8385b8664698a67b27d 233 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 218 2.4E-44 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Pfam PF01472 PUA domain 134 204 1.0E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 429 1.8E-42 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Gene3D G3DSA:3.40.50.620 213 460 1.7E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 605 616 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 SUPERFAMILY SSF88697 132 204 4.2E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Gene3D G3DSA:2.30.130.10 130 207 2.4E-14 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 SUPERFAMILY SSF54862 566 621 4.84E-14 T 23-10-2018 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 574 585 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 SMART SM00359 133 207 1.2E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Gene3D G3DSA:3.30.70.20 568 620 2.5E-10 T 23-10-2018 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 SUPERFAMILY SSF52402 223 415 7.94E-45 T 23-10-2018 A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 Pfam PF12838 4Fe-4S dicluster domain 574 616 1.6E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_07860 03da4d2dd9b5af1f0295b26606f42b98 629 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 94 203 8.0E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Gene3D G3DSA:3.10.310.40 302 407 4.3E-8 T 23-10-2018 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 2.4E-9 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Gene3D G3DSA:3.30.980.10 92 248 2.9E-40 T 23-10-2018 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 SUPERFAMILY SSF55186 92 238 1.07E-34 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 SUPERFAMILY SSF50447 1 89 1.55E-14 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Pfam PF02272 DHHA1 domain 270 401 2.0E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Pfam PF01411 tRNA synthetases class II (A) 20 94 2.9E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 SMART SM00863 191 234 4.9E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_00740 cb19d096554a03eb26dd2b9427e85882 407 Gene3D G3DSA:2.40.30.130 1 90 8.6E-19 T 23-10-2018 A3L14_04635 c525eefc7d147ee31a2bcd9a9d1ae4e0 201 SUPERFAMILY SSF109755 15 155 4.32E-7 T 23-10-2018 A3L14_04635 c525eefc7d147ee31a2bcd9a9d1ae4e0 201 Gene3D G3DSA:1.20.58.220 6 130 2.1E-5 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_09910 c218a9e73a5830695e78686312f125b8 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 8.8E-28 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 SUPERFAMILY SSF54675 2 115 1.96E-33 T 23-10-2018 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 PIRSF PIRSF000484 68 388 2.4E-50 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 PIRSF PIRSF000484 8 72 0.53 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 Gene3D G3DSA:3.20.140.10 315 389 8.6E-6 T 23-10-2018 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 Gene3D G3DSA:3.20.20.70 107 297 1.2E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 Gene3D G3DSA:3.90.1170.20 1 106 3.1E-45 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 52 113 4.8E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L14_09910 c218a9e73a5830695e78686312f125b8 390 SUPERFAMILY SSF51690 112 386 6.54E-78 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L14_05330 83475c98e61007433e736c10096587c9 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 1.6E-20 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L14_05330 83475c98e61007433e736c10096587c9 382 SUPERFAMILY SSF52922 275 378 5.23E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_05330 83475c98e61007433e736c10096587c9 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 257 4.8E-81 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_05330 83475c98e61007433e736c10096587c9 382 SUPERFAMILY SSF52518 12 265 4.52E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_05330 83475c98e61007433e736c10096587c9 382 Gene3D G3DSA:3.40.50.920 272 381 1.0E-24 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_05330 83475c98e61007433e736c10096587c9 382 Gene3D G3DSA:3.40.50.970 1 199 1.4E-83 T 23-10-2018 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 Gene3D G3DSA:2.40.30.130 13 84 3.5E-30 T 23-10-2018 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 Pfam PF01411 tRNA synthetases class II (A) 12 87 3.0E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 SMART SM00863 165 208 3.2E-7 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 208 4.1E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 SUPERFAMILY SSF50447 2 84 5.3E-20 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_07485 925e3941168907b0127979bd2cd6e654 213 SUPERFAMILY SSF55186 85 210 8.76E-33 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L14_07485 925e3941168907b0127979bd2cd6e654 213 Gene3D G3DSA:3.30.980.10 85 212 3.2E-42 T 23-10-2018 A3L14_08350 6f1854d83bea035eb00886a48055a2bb 333 SMART SM00797 23 300 6.0E-138 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L14_08350 6f1854d83bea035eb00886a48055a2bb 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 7.4E-85 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L14_08350 6f1854d83bea035eb00886a48055a2bb 333 Gene3D G3DSA:2.40.100.10 171 310 3.5E-49 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L14_08350 6f1854d83bea035eb00886a48055a2bb 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 308 3.2E-106 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L14_08350 6f1854d83bea035eb00886a48055a2bb 333 SUPERFAMILY SSF50891 174 290 1.4E-11 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 SUPERFAMILY SSF89095 482 624 4.32E-27 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Gene3D G3DSA:1.10.150.380 453 546 1.3E-23 T 23-10-2018 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 4.0E-56 T 23-10-2018 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 336.597 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 SMART SM00845 484 624 5.8E-36 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Pfam PF02637 GatB domain 485 624 6.5E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 SUPERFAMILY SSF55931 5 453 9.81E-102 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 6 627 1.4E-239 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Gene3D G3DSA:3.30.1360.30 274 404 3.1E-52 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Gene3D G3DSA:1.10.10.410 566 624 5.4E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Pfam PF02934 GatB/GatE catalytic domain 13 444 9.7E-67 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 SUPERFAMILY SSF55261 278 404 6.21E-46 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L14_04265 e8e656ec5b993c2f9bf721e5c0bbaecf 629 Pfam PF02938 GAD domain 299 390 1.0E-16 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A3L14_09415 b3a80734bbcf60e49a5e1b536c1016f4 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 1.8E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_09415 b3a80734bbcf60e49a5e1b536c1016f4 201 PIRSF PIRSF019239 29 201 4.0E-50 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_07530 9617ce568c785108118eea6ca5e098ac 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 1.7E-74 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A3L14_07530 9617ce568c785108118eea6ca5e098ac 330 SUPERFAMILY SSF52540 13 320 3.43E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07530 9617ce568c785108118eea6ca5e098ac 330 Pfam PF02374 Anion-transporting ATPase 12 326 5.4E-72 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A3L14_07530 9617ce568c785108118eea6ca5e098ac 330 Gene3D G3DSA:3.40.50.300 3 330 1.2E-86 T 23-10-2018 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 1.3E-62 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 SUPERFAMILY SSF51569 3 290 5.02E-87 T 23-10-2018 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 PIRSF PIRSF001365 1 291 4.5E-86 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 7.7E-22 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 7.7E-22 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 7.7E-22 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 7.7E-22 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 Gene3D G3DSA:3.20.20.70 1 289 7.3E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 SMART SM01130 1 289 5.5E-100 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 162 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A3L14_07765 4e17713da82ee40151c59991bfb2af41 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 287 1.3E-65 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_00975 f5a0e0ea2cbd59d6fed024289c989624 361 Gene3D G3DSA:3.20.20.70 24 286 1.1E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_00975 f5a0e0ea2cbd59d6fed024289c989624 361 SUPERFAMILY SSF102114 27 206 1.31E-24 T 23-10-2018 A3L14_00975 f5a0e0ea2cbd59d6fed024289c989624 361 Pfam PF13394 4Fe-4S single cluster domain 31 121 5.7E-6 T 23-10-2018 A3L14_00975 f5a0e0ea2cbd59d6fed024289c989624 361 Pfam PF04055 Radical SAM superfamily 32 184 2.9E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_00975 f5a0e0ea2cbd59d6fed024289c989624 361 ProSitePatterns PS01087 Radical activating enzymes signature. 23 45 - T 23-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 A3L14_00720 797e6945549ac5e1da2abfdbd579ebc3 102 Gene3D G3DSA:3.40.50.10580 1 102 7.4E-32 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00720 797e6945549ac5e1da2abfdbd579ebc3 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.28 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A3L14_00720 797e6945549ac5e1da2abfdbd579ebc3 102 SUPERFAMILY SSF159468 3 100 1.83E-19 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00720 797e6945549ac5e1da2abfdbd579ebc3 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 8.0E-18 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_02725 b9fcabec4268a9eb0470fa346c2c51e2 52 Gene3D G3DSA:2.20.28.70 1 49 1.3E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L14_02725 b9fcabec4268a9eb0470fa346c2c51e2 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.593 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L14_02725 b9fcabec4268a9eb0470fa346c2c51e2 52 SUPERFAMILY SSF57829 2 46 8.24E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_02725 b9fcabec4268a9eb0470fa346c2c51e2 52 SMART SM01377 1 46 8.9E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 6.0E-181 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Pfam PF03463 eRF1 domain 1 17 133 5.3E-8 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Gene3D G3DSA:3.30.1330.30 274 415 3.0E-42 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 SUPERFAMILY SSF55481 3 135 1.22E-47 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 SMART SM01194 1 135 1.4E-33 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 SUPERFAMILY SSF53137 138 271 2.27E-43 T 23-10-2018 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.317 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Gene3D G3DSA:3.30.420.60 131 271 1.3E-53 T 23-10-2018 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Pfam PF03465 eRF1 domain 3 276 414 7.5E-34 T 23-10-2018 IPR005142 eRF1 domain 3 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Gene3D G3DSA:3.30.960.10 1 130 1.8E-53 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 SUPERFAMILY SSF55315 272 414 7.65E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_04955 379a2c209400c9ea5866cb848a531a8f 415 Pfam PF03464 eRF1 domain 2 140 272 1.6E-49 T 23-10-2018 IPR005141 eRF1 domain 2 A3L14_00705 04ddafab3a11ca0d75c448c8795bbe53 162 Gene3D G3DSA:1.20.120.610 2 158 3.6E-40 T 23-10-2018 A3L14_00705 04ddafab3a11ca0d75c448c8795bbe53 162 SUPERFAMILY SSF81333 6 70 2.62E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L14_00705 04ddafab3a11ca0d75c448c8795bbe53 162 SUPERFAMILY SSF81333 89 156 1.1E-13 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L14_00705 04ddafab3a11ca0d75c448c8795bbe53 162 Pfam PF00137 ATP synthase subunit C 9 68 4.5E-12 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L14_00705 04ddafab3a11ca0d75c448c8795bbe53 162 Pfam PF00137 ATP synthase subunit C 97 155 2.8E-15 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 Gene3D G3DSA:3.20.20.70 10 375 6.5E-127 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 40.937 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 4.0E-131 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 SUPERFAMILY SSF51395 32 368 6.28E-79 T 23-10-2018 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 SMART SM01240 30 349 0.0031 T 23-10-2018 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 PIRSF PIRSF003314 7 363 1.3E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L14_02870 4877a24b2d9a653ffae2dee76d7b785e 376 Pfam PF01070 FMN-dependent dehydrogenase 14 346 3.1E-23 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L14_02830 c51536476750dd3b171a8ab8d555432b 278 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 1.1E-96 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A3L14_02830 c51536476750dd3b171a8ab8d555432b 278 SUPERFAMILY SSF53167 18 247 7.72E-75 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L14_02830 c51536476750dd3b171a8ab8d555432b 278 Gene3D G3DSA:3.40.50.1580 7 261 1.8E-85 T 23-10-2018 A3L14_02830 c51536476750dd3b171a8ab8d555432b 278 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_02830 c51536476750dd3b171a8ab8d555432b 278 Pfam PF01048 Phosphorylase superfamily 31 256 4.9E-45 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L14_04410 bf3a989a16ecd78c5d80733458b5e2cd 352 SUPERFAMILY SSF46785 4 83 2.46E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04410 bf3a989a16ecd78c5d80733458b5e2cd 352 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 76 1.3E-17 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_04410 bf3a989a16ecd78c5d80733458b5e2cd 352 SUPERFAMILY SSF159071 262 348 7.85E-21 T 23-10-2018 A3L14_04410 bf3a989a16ecd78c5d80733458b5e2cd 352 Pfam PF11495 Archaeal transcriptional regulator TrmB 113 349 1.2E-51 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L14_04410 bf3a989a16ecd78c5d80733458b5e2cd 352 Gene3D G3DSA:1.10.10.10 5 104 2.8E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01855 b5c118f9168e148fcda81f8e1bcbd28b 355 Gene3D G3DSA:3.40.50.300 15 214 3.2E-28 T 23-10-2018 A3L14_01855 b5c118f9168e148fcda81f8e1bcbd28b 355 SUPERFAMILY SSF52540 27 251 1.67E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01855 b5c118f9168e148fcda81f8e1bcbd28b 355 SMART SM00382 26 195 9.6E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01855 b5c118f9168e148fcda81f8e1bcbd28b 355 SUPERFAMILY SSF52540 5 138 5.18E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01855 b5c118f9168e148fcda81f8e1bcbd28b 355 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 209 5.7E-41 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 23-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 Gene3D G3DSA:1.10.10.10 1 118 8.6E-36 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 SMART SM00418 33 112 5.4E-33 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 Pfam PF01022 Bacterial regulatory protein, arsR family 40 85 3.3E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 5.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 5.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 5.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 5.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07110 90f9911d0bb8e7412eb106ba1f501d6a 118 SUPERFAMILY SSF46785 23 114 4.05E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07795 57904f77a5268e3846e3ef66a898e00c 404 Pfam PF00155 Aminotransferase class I and II 35 396 3.0E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_07795 57904f77a5268e3846e3ef66a898e00c 404 Gene3D G3DSA:3.40.640.10 70 294 1.9E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_07795 57904f77a5268e3846e3ef66a898e00c 404 Gene3D G3DSA:3.90.1150.10 22 397 1.9E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_07795 57904f77a5268e3846e3ef66a898e00c 404 SUPERFAMILY SSF53383 6 401 3.85E-104 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 SUPERFAMILY SSF55315 3 96 1.31E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 4.3E-20 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 30.042 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03405 339f673f2da98fc2915303c8e8d9086a 101 Gene3D G3DSA:3.30.1330.30 1 101 7.1E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_01445 41acb46d9380c340953a90754bf259b0 145 Gene3D G3DSA:3.40.50.1010 1 124 2.9E-14 T 23-10-2018 A3L14_01445 41acb46d9380c340953a90754bf259b0 145 SUPERFAMILY SSF88723 2 128 5.61E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_01445 41acb46d9380c340953a90754bf259b0 145 Pfam PF01850 PIN domain 4 120 3.5E-13 T 23-10-2018 IPR002716 PIN domain A3L14_03760 aed5868bde4e10966a9aacc750a53e93 254 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 40 5.3E-8 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal A3L14_03760 aed5868bde4e10966a9aacc750a53e93 254 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 4 159 1.5E-38 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 90 5.8E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 Pfam PF00120 Glutamine synthetase, catalytic domain 101 440 4.4E-125 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 14 441 2.6E-172 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 SMART SM01230 100 343 2.7E-132 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 226 241 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 Gene3D G3DSA:3.30.590.10 103 443 2.6E-124 T 23-10-2018 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 SUPERFAMILY SSF55931 100 442 1.67E-119 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 SUPERFAMILY SSF54368 13 84 1.7E-18 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L14_00830 b1134728d78d0c04358ef9bd27442aa6 443 Gene3D G3DSA:3.10.20.70 7 102 1.7E-21 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L14_01945 47d4a10d80914fd1c51f69666e93c42c 281 SMART SM00518 4 276 3.8E-81 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L14_01945 47d4a10d80914fd1c51f69666e93c42c 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 7.4E-18 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L14_01945 47d4a10d80914fd1c51f69666e93c42c 281 Gene3D G3DSA:3.20.20.150 12 281 4.8E-40 T 23-10-2018 A3L14_01945 47d4a10d80914fd1c51f69666e93c42c 281 SUPERFAMILY SSF51658 7 279 4.81E-60 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L14_06405 45f736b19c51f5da34e552de4066836c 246 Gene3D G3DSA:3.40.50.11590 102 217 2.9E-24 T 23-10-2018 A3L14_06405 45f736b19c51f5da34e552de4066836c 246 Pfam PF04016 Putative heavy-metal chelation 109 241 3.2E-34 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A3L14_06405 45f736b19c51f5da34e552de4066836c 246 Pfam PF13938 Putative heavy-metal chelation 8 90 2.0E-12 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A3L14_06405 45f736b19c51f5da34e552de4066836c 246 SUPERFAMILY SSF159713 5 243 1.96E-59 T 23-10-2018 A3L14_06405 45f736b19c51f5da34e552de4066836c 246 Gene3D G3DSA:3.30.390.100 16 221 2.9E-24 T 23-10-2018 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 PIRSF PIRSF000521 136 443 1.2E-54 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 PIRSF PIRSF000521 2 144 2.4E-7 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 Gene3D G3DSA:3.40.640.10 72 340 8.6E-151 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 Gene3D G3DSA:3.90.1150.10 15 438 8.6E-151 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 Pfam PF00202 Aminotransferase class-III 34 438 8.7E-114 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_11435 43e3fe2727b781c8c0d12e73ec811d70 445 SUPERFAMILY SSF53383 33 441 1.83E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_01860 68bd52dedfb5602f1f3763fb0ef65f7e 276 Gene3D G3DSA:1.20.120.1780 159 276 4.2E-5 T 23-10-2018 A3L14_01860 68bd52dedfb5602f1f3763fb0ef65f7e 276 Pfam PF01040 UbiA prenyltransferase family 23 256 2.0E-43 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L14_01860 68bd52dedfb5602f1f3763fb0ef65f7e 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.531 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A3L14_01860 68bd52dedfb5602f1f3763fb0ef65f7e 276 Gene3D G3DSA:1.10.357.140 9 158 5.2E-15 T 23-10-2018 A3L14_00075 e72781ec4319ef14e542c4ce5b1b1147 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 62 1.2E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_00075 e72781ec4319ef14e542c4ce5b1b1147 160 Gene3D G3DSA:3.40.50.620 6 153 4.5E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00075 e72781ec4319ef14e542c4ce5b1b1147 160 SUPERFAMILY SSF52374 4 147 1.49E-19 T 23-10-2018 A3L14_00075 e72781ec4319ef14e542c4ce5b1b1147 160 Pfam PF01467 Cytidylyltransferase-like 9 145 2.8E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 SUPERFAMILY SSF53613 1 274 1.71E-53 T 23-10-2018 IPR029056 Ribokinase-like A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 Pfam PF00294 pfkB family carbohydrate kinase 4 274 2.0E-37 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 PRINTS PR00990 Ribokinase signature 23 42 9.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 PRINTS PR00990 Ribokinase signature 201 212 9.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 PRINTS PR00990 Ribokinase signature 162 177 9.3E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 Gene3D G3DSA:3.40.1190.20 2 276 7.0E-59 T 23-10-2018 IPR029056 Ribokinase-like A3L14_00350 6a9ebff0cf81203f425db8cc046a0fc6 277 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 232 245 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L14_10040 0f9c649b1f26031df72382f5793ca945 388 Gene3D G3DSA:1.20.1250.20 10 199 2.7E-15 T 23-10-2018 A3L14_10040 0f9c649b1f26031df72382f5793ca945 388 Pfam PF07690 Major Facilitator Superfamily 24 345 1.7E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_10040 0f9c649b1f26031df72382f5793ca945 388 Gene3D G3DSA:1.20.1250.20 209 388 4.5E-15 T 23-10-2018 A3L14_10040 0f9c649b1f26031df72382f5793ca945 388 SUPERFAMILY SSF103473 11 386 3.79E-41 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 SUPERFAMILY SSF53738 147 248 7.46E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 385 435 8.7E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 6.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 6.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 6.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 6.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 SUPERFAMILY SSF53738 250 351 1.02E-12 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Gene3D G3DSA:3.30.310.50 349 453 1.9E-17 T 23-10-2018 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 439 9.3E-146 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 SUPERFAMILY SSF53738 2 169 2.08E-40 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Gene3D G3DSA:3.40.120.10 246 348 3.0E-47 T 23-10-2018 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 130 3.1E-38 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Gene3D G3DSA:3.40.120.10 161 344 3.0E-47 T 23-10-2018 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 357 1.9E-7 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Gene3D G3DSA:3.40.120.10 1 145 7.2E-46 T 23-10-2018 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 150 245 9.1E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_00920 64ad4b231a502c75d7761333ee1e3781 453 SUPERFAMILY SSF55957 346 448 3.92E-21 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_01245 caf0862396c84c83fef6645527f9e240 315 Gene3D G3DSA:1.10.10.10 1 75 2.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01245 caf0862396c84c83fef6645527f9e240 315 Pfam PF01047 MarR family 2 51 5.4E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L14_01245 caf0862396c84c83fef6645527f9e240 315 SUPERFAMILY SSF46785 2 74 3.48E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00400 b86c76b291101c3bbf59e809bf88443b 322 Gene3D G3DSA:3.40.50.620 1 318 7.6E-85 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00400 b86c76b291101c3bbf59e809bf88443b 322 Pfam PF01171 PP-loop family 50 227 1.7E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L14_00400 b86c76b291101c3bbf59e809bf88443b 322 SUPERFAMILY SSF52402 36 270 1.08E-52 T 23-10-2018 A3L14_00400 b86c76b291101c3bbf59e809bf88443b 322 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 307 6.0E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L14_00400 b86c76b291101c3bbf59e809bf88443b 322 PIRSF PIRSF004976 1 317 2.4E-109 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L14_05200 94ec6da8f3ebb20cfa5b00a55063c038 286 Pfam PF01435 Peptidase family M48 70 278 2.5E-26 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L14_05200 94ec6da8f3ebb20cfa5b00a55063c038 286 Gene3D G3DSA:3.30.2010.10 61 151 3.0E-22 T 23-10-2018 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.241 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 SMART SM01393 18 125 4.3E-61 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 19 125 1.0E-53 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 Pfam PF01655 Ribosomal protein L32 18 125 5.2E-40 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02565 0d008ff34e6593482886d24afe7e50ae 127 SUPERFAMILY SSF52042 5 126 1.44E-45 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 Gene3D G3DSA:3.90.230.10 131 356 2.8E-84 T 23-10-2018 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 Gene3D G3DSA:3.40.350.10 1 129 1.3E-34 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 PRINTS PR00599 Methionine aminopeptidase-1 signature 210 226 5.3E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 PRINTS PR00599 Methionine aminopeptidase-1 signature 308 320 5.3E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 Pfam PF00557 Metallopeptidase family M24 138 340 1.3E-70 T 23-10-2018 IPR000994 Peptidase M24 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 131 1.7E-21 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 SUPERFAMILY SSF53092 2 129 9.24E-19 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_02925 7477cd8746078a4b63d8d3063c174523 357 SUPERFAMILY SSF55920 130 356 6.02E-77 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L14_06600 99d8742a7cdcdb8f1314f510ed9fef77 128 SUPERFAMILY SSF81593 3 121 4.71E-27 T 23-10-2018 A3L14_06600 99d8742a7cdcdb8f1314f510ed9fef77 128 Gene3D G3DSA:1.20.120.330 1 124 1.9E-34 T 23-10-2018 A3L14_06600 99d8742a7cdcdb8f1314f510ed9fef77 128 Pfam PF05168 HEPN domain 5 114 4.2E-32 T 23-10-2018 IPR007842 HEPN domain A3L14_06600 99d8742a7cdcdb8f1314f510ed9fef77 128 SMART SM00748 9 115 2.9E-19 T 23-10-2018 IPR007842 HEPN domain A3L14_05090 b5c5c79cad301208a594baf4d5b91ebf 143 Gene3D G3DSA:3.40.50.1010 4 139 2.3E-17 T 23-10-2018 A3L14_05090 b5c5c79cad301208a594baf4d5b91ebf 143 SMART SM00670 2 131 1.3E-13 T 23-10-2018 IPR002716 PIN domain A3L14_05090 b5c5c79cad301208a594baf4d5b91ebf 143 Pfam PF01850 PIN domain 5 130 2.6E-23 T 23-10-2018 IPR002716 PIN domain A3L14_05090 b5c5c79cad301208a594baf4d5b91ebf 143 SUPERFAMILY SSF88723 1 131 1.12E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05090 b5c5c79cad301208a594baf4d5b91ebf 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 139 9.564 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_10700 8c322bb4863fff42a2c08f00b7cea216 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 8.8E-187 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L14_10700 8c322bb4863fff42a2c08f00b7cea216 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L14_10700 8c322bb4863fff42a2c08f00b7cea216 375 PIRSF PIRSF015647 5 375 4.4E-191 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L14_10700 8c322bb4863fff42a2c08f00b7cea216 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 61.51 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L14_10700 8c322bb4863fff42a2c08f00b7cea216 375 SUPERFAMILY SSF111249 6 372 3.66E-177 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 SMART SM00632 426 502 4.0E-4 T 23-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Gene3D G3DSA:3.20.20.80 23 416 4.9E-104 T 23-10-2018 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 SUPERFAMILY SSF51011 423 501 3.31E-16 T 23-10-2018 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Gene3D G3DSA:2.60.40.10 505 582 1.3E-15 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Pfam PF16657 Maltogenic Amylase, C-terminal domain 423 496 6.8E-9 T 23-10-2018 IPR032091 Maltogenic Amylase, C-terminal A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 SUPERFAMILY SSF51445 24 420 8.65E-79 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Gene3D G3DSA:2.60.40.1180 417 500 1.5E-13 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 SMART SM00642 31 414 3.2E-78 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Pfam PF00128 Alpha amylase, catalytic domain 62 381 3.3E-54 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 SUPERFAMILY SSF81296 505 575 8.4E-14 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L14_10420 6b1af52912a65776872c3400fc1844c8 723 Pfam PF01833 IPT/TIG domain 506 580 6.8E-10 T 23-10-2018 IPR002909 IPT domain A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 SUPERFAMILY SSF51395 1 298 5.0E-83 T 23-10-2018 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 Gene3D G3DSA:2.30.26.10 55 212 1.6E-91 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 PIRSF PIRSF000164 1 300 2.6E-87 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 7.9E-64 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 Gene3D G3DSA:3.20.20.70 12 289 1.6E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 3.8E-128 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.306 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A3L14_09850 769adc89fadd8be2e023c26388f2d1e4 301 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L14_06425 4428eb28fa8bb37c0d558b232281474a 296 Gene3D G3DSA:3.40.50.300 92 290 2.5E-10 T 23-10-2018 A3L14_06425 4428eb28fa8bb37c0d558b232281474a 296 SUPERFAMILY SSF52540 91 285 2.7E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06425 4428eb28fa8bb37c0d558b232281474a 296 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 294 45.228 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A3L14_06425 4428eb28fa8bb37c0d558b232281474a 296 Pfam PF03477 ATP cone domain 13 86 6.6E-10 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L14_10345 ebaeac74b457ead8b625fd8489931e1c 192 Gene3D G3DSA:3.40.50.300 2 189 5.1E-44 T 23-10-2018 A3L14_10345 ebaeac74b457ead8b625fd8489931e1c 192 Pfam PF13238 AAA domain 3 142 2.6E-17 T 23-10-2018 A3L14_10345 ebaeac74b457ead8b625fd8489931e1c 192 SUPERFAMILY SSF52540 1 189 3.01E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00375 448acb414066464da9e010675b6b5019 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 198 3.2E-73 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 36.846 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 3.3E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 3.3E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 3.3E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 3.3E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 3.3E-41 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 PIRSF PIRSF015592 1 200 7.5E-76 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 Gene3D G3DSA:3.40.630.20 1 199 5.8E-76 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 SUPERFAMILY SSF53182 1 198 8.63E-70 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L14_00375 448acb414066464da9e010675b6b5019 200 Pfam PF01470 Pyroglutamyl peptidase 1 198 8.6E-75 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 Gene3D G3DSA:1.10.8.50 1 76 2.4E-25 T 23-10-2018 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 PIRSF PIRSF002134 2 149 1.1E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.161 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 SUPERFAMILY SSF46946 9 148 1.91E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 1.3E-40 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 3.4E-61 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02655 43ffac43989d3b22d74e84e122901809 149 Gene3D G3DSA:4.10.910.10 88 138 4.3E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02645 c4ba79adfecd11a8a4cd3f882082b7c2 195 Pfam PF05175 Methyltransferase small domain 27 191 1.2E-43 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L14_02645 c4ba79adfecd11a8a4cd3f882082b7c2 195 SUPERFAMILY SSF53335 6 190 9.64E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_02645 c4ba79adfecd11a8a4cd3f882082b7c2 195 Gene3D G3DSA:3.40.50.150 5 193 5.8E-50 T 23-10-2018 A3L14_06140 4c1cc4fd1a4655e5629ecc964c0b852a 427 SUPERFAMILY SSF56801 57 377 3.14E-25 T 23-10-2018 A3L14_06140 4c1cc4fd1a4655e5629ecc964c0b852a 427 ProSitePatterns PS00455 Putative AMP-binding domain signature. 81 92 - T 23-10-2018 IPR020845 AMP-binding, conserved site A3L14_06140 4c1cc4fd1a4655e5629ecc964c0b852a 427 Gene3D G3DSA:3.40.50.12780 8 315 2.0E-27 T 23-10-2018 A3L14_06140 4c1cc4fd1a4655e5629ecc964c0b852a 427 Pfam PF00501 AMP-binding enzyme 80 238 4.2E-12 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 SUPERFAMILY SSF52317 2 195 4.88E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.225 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 194 5.7E-73 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 4.5E-54 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 Gene3D G3DSA:3.40.50.880 1 197 1.0E-67 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01345 23c2b0cc1bef82c31df2db5e872163b7 197 PIRSF PIRSF005639 1 197 2.2E-68 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_02260 d7e5f42a9479d3e4725e2bb04b28658f 522 SUPERFAMILY SSF52096 244 522 6.71E-93 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L14_02260 d7e5f42a9479d3e4725e2bb04b28658f 522 Gene3D G3DSA:3.90.226.10 262 522 2.8E-96 T 23-10-2018 A3L14_02260 d7e5f42a9479d3e4725e2bb04b28658f 522 Gene3D G3DSA:3.90.226.10 1 260 7.3E-98 T 23-10-2018 A3L14_02260 d7e5f42a9479d3e4725e2bb04b28658f 522 Pfam PF01039 Carboxyl transferase domain 28 520 7.9E-203 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A3L14_02260 d7e5f42a9479d3e4725e2bb04b28658f 522 SUPERFAMILY SSF52096 3 257 7.32E-80 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 SUPERFAMILY SSF52540 1 315 1.22E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 3.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 3.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 3.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 3.6E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 SUPERFAMILY SSF81271 323 393 1.01E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 Gene3D G3DSA:1.10.8.470 126 215 6.4E-31 T 23-10-2018 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 Pfam PF02824 TGS domain 341 393 5.0E-14 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 Gene3D G3DSA:3.10.20.30 319 397 9.3E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 Pfam PF01926 50S ribosome-binding GTPase 2 121 2.9E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_05950 f167f0d3d04833c2c3919221f9080b2e 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 5.8E-35 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A3L14_05370 b4b77172ced96eb3993c2605fb7790c8 259 Gene3D G3DSA:3.40.1210.10 3 256 3.1E-82 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L14_05370 b4b77172ced96eb3993c2605fb7790c8 259 Pfam PF01975 Survival protein SurE 4 194 1.6E-53 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L14_05370 b4b77172ced96eb3993c2605fb7790c8 259 SUPERFAMILY SSF64167 3 253 7.59E-70 T 23-10-2018 A3L14_05370 b4b77172ced96eb3993c2605fb7790c8 259 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 244 4.0E-68 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L14_05370 b4b77172ced96eb3993c2605fb7790c8 259 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 259 32.115 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 Pfam PF02223 Thymidylate kinase 8 196 4.5E-54 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 Gene3D G3DSA:3.40.50.300 1 204 8.0E-69 T 23-10-2018 A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 Hamap MF_00165 Thymidylate kinase [tmk]. 3 204 28.098 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 SUPERFAMILY SSF52540 3 201 1.18E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 3.4E-58 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L14_03535 91ebc1242e7cf1ac602828e8b0753d5a 207 ProSitePatterns PS01331 Thymidylate kinase signature. 98 110 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L14_00750 1b1abf4650c715fa89e56e9d3dd7a88a 394 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 211 389 6.3E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00750 1b1abf4650c715fa89e56e9d3dd7a88a 394 Gene3D G3DSA:1.10.3720.10 184 392 1.5E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00750 1b1abf4650c715fa89e56e9d3dd7a88a 394 SUPERFAMILY SSF161098 189 382 1.14E-16 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 4.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 4.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 SMART SM00418 55 133 1.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 Pfam PF01022 Bacterial regulatory protein, arsR family 62 108 1.6E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 SUPERFAMILY SSF46785 47 122 3.05E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05720 d0e110a599208d378c889fc7d5dd5061 136 Gene3D G3DSA:1.10.10.10 34 124 2.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 SUPERFAMILY SSF48557 4 443 2.83E-135 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 Gene3D G3DSA:1.20.200.10 101 359 2.9E-95 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 SMART SM00998 360 439 1.7E-29 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 Gene3D G3DSA:1.10.275.10 1 100 1.4E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 2.3E-11 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 2.3E-11 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 2.3E-11 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 2.3E-11 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 8.8E-18 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 1.8E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 1.8E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 1.8E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 1.8E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 Gene3D G3DSA:1.10.40.30 360 439 1.1E-21 T 23-10-2018 A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 Pfam PF00206 Lyase 13 293 4.8E-55 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L14_07650 db1e2ad0444ef9065a2fced2e4d0d85c 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 1.7E-184 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 SMART SM00382 26 217 3.6E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 237 1.4E-87 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 Pfam PF00005 ABC transporter 17 167 1.7E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 Gene3D G3DSA:3.40.50.300 1 241 1.9E-58 T 23-10-2018 A3L14_07210 71952c9f3b1696330609c2d484c4ec39 247 SUPERFAMILY SSF52540 2 225 4.53E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Gene3D G3DSA:2.10.230.10 1 88 2.2E-6 T 23-10-2018 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Gene3D G3DSA:2.40.50.140 128 202 2.0E-13 T 23-10-2018 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 1.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Pfam PF00575 S1 RNA binding domain 131 193 9.7E-11 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Gene3D G3DSA:3.90.1640.30 332 529 1.3E-8 T 23-10-2018 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 SUPERFAMILY SSF50249 225 296 2.06E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 SUPERFAMILY SSF57938 5 32 4.32E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 SMART SM00316 131 196 6.3E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 Gene3D G3DSA:2.40.50.140 218 304 2.6E-7 T 23-10-2018 A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 SUPERFAMILY SSF64182 336 734 1.2E-41 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L14_02050 e6708c842de4a43a67748bb4817e4869 741 SUPERFAMILY SSF50249 121 192 2.5E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 Pfam PF12146 Serine aminopeptidase, S33 14 240 5.4E-67 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 Gene3D G3DSA:3.40.50.1820 1 259 2.3E-66 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 6.4E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 6.4E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 6.4E-5 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L14_07555 4877c77dd17eb20a1e00d0aaf8e8c322 263 SUPERFAMILY SSF53474 9 253 9.17E-48 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L14_05930 0ff429b40f83f0de0ee8e52ec83c1a2f 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 7.2E-22 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A3L14_05930 0ff429b40f83f0de0ee8e52ec83c1a2f 267 SUPERFAMILY SSF143597 91 260 2.75E-31 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L14_05930 0ff429b40f83f0de0ee8e52ec83c1a2f 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 34.463 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L14_05930 0ff429b40f83f0de0ee8e52ec83c1a2f 267 Gene3D G3DSA:3.40.1700.10 173 265 5.2E-15 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L14_05930 0ff429b40f83f0de0ee8e52ec83c1a2f 267 PIRSF PIRSF019073 3 267 1.2E-76 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L14_09000 592501c7ac0ee51848ac474963fd47b0 217 Gene3D G3DSA:2.40.30.70 6 138 8.6E-31 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L14_09000 592501c7ac0ee51848ac474963fd47b0 217 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 16 129 1.1E-33 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L14_09000 592501c7ac0ee51848ac474963fd47b0 217 Pfam PF01980 Uncharacterised protein family UPF0066 16 125 1.7E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L14_09000 592501c7ac0ee51848ac474963fd47b0 217 SUPERFAMILY SSF118196 4 134 1.96E-38 T 23-10-2018 IPR036413 YaeB-like superfamily A3L14_09000 592501c7ac0ee51848ac474963fd47b0 217 ProSitePatterns PS01318 TsaA-like domain signature. 73 84 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Gene3D G3DSA:3.30.310.50 360 446 2.6E-22 T 23-10-2018 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 441 8.5E-9 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Gene3D G3DSA:3.40.120.10 164 345 6.0E-56 T 23-10-2018 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 4.3E-20 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 SUPERFAMILY SSF53738 252 355 7.46E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 1.7E-164 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 7.0E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 SUPERFAMILY SSF53738 3 171 1.22E-45 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 246 6.0E-20 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Gene3D G3DSA:3.40.120.10 247 330 6.0E-56 T 23-10-2018 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Gene3D G3DSA:3.40.120.10 1 147 1.2E-50 T 23-10-2018 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.721 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 SUPERFAMILY SSF55957 348 446 3.79E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10365 108d09f6ec7edeb619703c336a5476f3 449 SUPERFAMILY SSF53738 150 249 1.26E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_10590 5035598fe06910d276031ae814c0ce4b 311 Gene3D G3DSA:3.40.50.970 99 310 3.1E-69 T 23-10-2018 A3L14_10590 5035598fe06910d276031ae814c0ce4b 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 2.5E-19 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_10590 5035598fe06910d276031ae814c0ce4b 311 SUPERFAMILY SSF52518 17 308 6.58E-73 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 SUPERFAMILY SSF53383 4 391 4.57E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 Gene3D G3DSA:3.90.1150.10 35 385 2.1E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 Pfam PF00155 Aminotransferase class I and II 40 383 2.8E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 Gene3D G3DSA:3.40.640.10 55 291 2.1E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_10175 d671abb7fe21a492308ace4e9dcddac6 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 4.5E-203 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A3L14_04790 ea98806464f8287c1c778bb582998602 103 SUPERFAMILY SSF51182 7 100 5.94E-25 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_04790 ea98806464f8287c1c778bb582998602 103 Gene3D G3DSA:2.60.120.10 7 103 4.0E-25 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_04790 ea98806464f8287c1c778bb582998602 103 Pfam PF07883 Cupin domain 33 100 1.4E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L14_07290 a7909062d7053af9854ab7e9293f5bd9 179 SUPERFAMILY SSF47240 11 147 3.52E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07290 a7909062d7053af9854ab7e9293f5bd9 179 Gene3D G3DSA:1.20.1260.10 5 148 7.4E-29 T 23-10-2018 IPR012347 Ferritin-like A3L14_07290 a7909062d7053af9854ab7e9293f5bd9 179 Pfam PF02915 Rubrerythrin 15 141 2.8E-20 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_10555 89012972df68c8ae67438f031bffefe8 111 SMART SM01407 6 66 2.4E-17 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L14_10555 89012972df68c8ae67438f031bffefe8 111 Gene3D G3DSA:1.10.8.10 70 109 1.6E-20 T 23-10-2018 A3L14_10555 89012972df68c8ae67438f031bffefe8 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 1.6E-36 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L14_10555 89012972df68c8ae67438f031bffefe8 111 Pfam PF01849 NAC domain 6 62 5.1E-11 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L14_10555 89012972df68c8ae67438f031bffefe8 111 SUPERFAMILY SSF46934 70 110 3.57E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A3L14_10555 89012972df68c8ae67438f031bffefe8 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.528 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L14_10555 89012972df68c8ae67438f031bffefe8 111 Gene3D G3DSA:2.20.70.30 10 68 1.1E-22 T 23-10-2018 IPR038187 NAC A/B domain superfamily A3L14_09775 8535b52bc12a5d7b72ef4ca94176bc28 581 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 371 571 2.7E-6 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A3L14_09775 8535b52bc12a5d7b72ef4ca94176bc28 581 SUPERFAMILY SSF56219 349 580 2.36E-31 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L14_09775 8535b52bc12a5d7b72ef4ca94176bc28 581 Gene3D G3DSA:3.60.10.10 353 581 6.8E-31 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L14_06095 31cf57bb130d75c92565bf14707bb4e0 335 Gene3D G3DSA:3.40.50.10210 1 333 5.6E-125 T 23-10-2018 A3L14_06095 31cf57bb130d75c92565bf14707bb4e0 335 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 2.2E-98 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L14_06095 31cf57bb130d75c92565bf14707bb4e0 335 Hamap MF_01086 UPF0284 protein . 1 335 135.787 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L14_06095 31cf57bb130d75c92565bf14707bb4e0 335 SUPERFAMILY SSF52733 18 327 5.36E-42 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L14_11135 fbaf406bab2d728a6dbe0dee5e0e0970 208 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.005 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L14_11135 fbaf406bab2d728a6dbe0dee5e0e0970 208 SUPERFAMILY SSF111278 2 182 8.24E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_11135 fbaf406bab2d728a6dbe0dee5e0e0970 208 Pfam PF02676 Methyltransferase TYW3 3 184 1.9E-38 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_11135 fbaf406bab2d728a6dbe0dee5e0e0970 208 Gene3D G3DSA:3.30.1960.10 1 183 6.6E-49 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 4.5E-106 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 SUPERFAMILY SSF51621 4 262 2.55E-102 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 Gene3D G3DSA:3.20.20.60 2 272 2.8E-110 T 23-10-2018 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 262 2.0E-89 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 PIRSF PIRSF000388 1 265 3.8E-103 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L14_06310 b2b99797fb01d91929b557fddebb3698 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.204 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L14_03030 890a89e835fe20ebd98f771e93f0c272 387 Gene3D G3DSA:3.40.50.300 1 183 7.3E-13 T 23-10-2018 A3L14_02960 2cdb20231023f2ffbe01ea3ed4e5b937 220 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 116 208 4.0E-39 T 23-10-2018 A3L14_02960 2cdb20231023f2ffbe01ea3ed4e5b937 220 Gene3D G3DSA:3.20.20.140 1 219 1.6E-100 T 23-10-2018 A3L14_02960 2cdb20231023f2ffbe01ea3ed4e5b937 220 SUPERFAMILY SSF89550 12 216 3.1E-32 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L14_02960 2cdb20231023f2ffbe01ea3ed4e5b937 220 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 10 220 23.195 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A3L14_02960 2cdb20231023f2ffbe01ea3ed4e5b937 220 Pfam PF01876 RNase P subunit p30 25 209 1.5E-31 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 Gene3D G3DSA:3.40.50.720 11 206 2.8E-71 T 23-10-2018 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 SUPERFAMILY SSF52413 312 412 2.22E-26 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 SMART SM00984 322 413 7.8E-36 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 SUPERFAMILY SSF48179 209 298 5.1E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 408 3.4E-127 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 295 2.2E-24 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 190 1.4E-50 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 413 2.4E-24 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 PIRSF PIRSF500136 1 424 3.5E-145 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 PIRSF PIRSF000124 10 416 8.6E-82 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 SUPERFAMILY SSF51735 12 201 1.14E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_04915 d4e93d2d8ef72e392e74a0f3a423e9e1 428 Gene3D G3DSA:3.40.50.720 240 428 2.3E-68 T 23-10-2018 A3L14_07230 084b619d0030b673720bd3fd10e64cb1 179 Pfam PF08241 Methyltransferase domain 41 122 1.1E-12 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L14_07230 084b619d0030b673720bd3fd10e64cb1 179 SUPERFAMILY SSF53335 34 173 8.22E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_07230 084b619d0030b673720bd3fd10e64cb1 179 Gene3D G3DSA:3.40.50.150 1 175 1.4E-33 T 23-10-2018 A3L14_03410 8fe1c5cf81b1fb85de08c20353c60967 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.278 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03410 8fe1c5cf81b1fb85de08c20353c60967 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 2.9E-151 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03410 8fe1c5cf81b1fb85de08c20353c60967 391 Gene3D G3DSA:1.10.150.390 333 378 5.4E-23 T 23-10-2018 A3L14_03410 8fe1c5cf81b1fb85de08c20353c60967 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 51 332 5.3E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03410 8fe1c5cf81b1fb85de08c20353c60967 391 SUPERFAMILY SSF64484 25 385 1.24E-106 T 23-10-2018 A3L14_08355 27314704b62a438b60ef87613ae442ad 229 SUPERFAMILY SSF50891 86 216 4.55E-52 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L14_08355 27314704b62a438b60ef87613ae442ad 229 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 209 2.4E-73 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L14_08355 27314704b62a438b60ef87613ae442ad 229 Gene3D G3DSA:2.40.100.10 85 225 6.1E-66 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L14_08355 27314704b62a438b60ef87613ae442ad 229 SMART SM00796 1 200 2.6E-111 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L14_08355 27314704b62a438b60ef87613ae442ad 229 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 200 1.8E-79 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L14_08355 27314704b62a438b60ef87613ae442ad 229 Gene3D G3DSA:3.30.1360.40 1 83 1.3E-25 T 23-10-2018 A3L14_08355 27314704b62a438b60ef87613ae442ad 229 SUPERFAMILY SSF160467 2 91 1.7E-22 T 23-10-2018 A3L14_05550 251406be2f388daa53d0b907ebee8860 867 Pfam PF00271 Helicase conserved C-terminal domain 278 384 1.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_05550 251406be2f388daa53d0b907ebee8860 867 Pfam PF00270 DEAD/DEAH box helicase 38 222 1.9E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_05550 251406be2f388daa53d0b907ebee8860 867 PIRSF PIRSF037307 7 864 1.0E-286 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L14_05550 251406be2f388daa53d0b907ebee8860 867 SUPERFAMILY SSF52540 49 392 2.99E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05550 251406be2f388daa53d0b907ebee8860 867 Pfam PF08494 DEAD/H associated 642 830 6.4E-55 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L14_05550 251406be2f388daa53d0b907ebee8860 867 Gene3D G3DSA:3.40.50.300 16 237 5.4E-53 T 23-10-2018 A3L14_05550 251406be2f388daa53d0b907ebee8860 867 SMART SM00487 33 261 1.0E-32 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_05550 251406be2f388daa53d0b907ebee8860 867 SMART SM00490 302 388 7.5E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_05550 251406be2f388daa53d0b907ebee8860 867 SMART SM00382 50 428 0.0045 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05550 251406be2f388daa53d0b907ebee8860 867 Gene3D G3DSA:3.40.50.300 267 420 9.8E-25 T 23-10-2018 A3L14_04720 24a53d46bbd799268923d923392a9305 155 Gene3D G3DSA:3.90.280.10 5 155 8.7E-53 T 23-10-2018 IPR036610 PEBP-like superfamily A3L14_04720 24a53d46bbd799268923d923392a9305 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 152 1.6E-42 T 23-10-2018 IPR005247 YbhB/YbcL A3L14_04720 24a53d46bbd799268923d923392a9305 155 SUPERFAMILY SSF49777 7 154 3.14E-46 T 23-10-2018 IPR036610 PEBP-like superfamily A3L14_04720 24a53d46bbd799268923d923392a9305 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 15 152 1.7E-35 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A3L14_03155 61290075d0c024f46085635ce5c755e1 131 Pfam PF05168 HEPN domain 8 120 6.3E-20 T 23-10-2018 IPR007842 HEPN domain A3L14_03155 61290075d0c024f46085635ce5c755e1 131 Gene3D G3DSA:1.20.120.330 2 125 3.2E-29 T 23-10-2018 A3L14_04830 a8ba316953b173557ba0c8d3bfc04538 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04830 a8ba316953b173557ba0c8d3bfc04538 391 Gene3D G3DSA:1.10.645.20 27 391 2.6E-113 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04830 a8ba316953b173557ba0c8d3bfc04538 391 SUPERFAMILY SSF56762 38 391 1.83E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04830 a8ba316953b173557ba0c8d3bfc04538 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 3.9E-70 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_08190 c694728a7174ae05d6e46f0daef90bae 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 257 3.9E-46 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_08190 c694728a7174ae05d6e46f0daef90bae 273 Gene3D G3DSA:3.40.50.1100 3 263 1.1E-70 T 23-10-2018 A3L14_08190 c694728a7174ae05d6e46f0daef90bae 273 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 7 21 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A3L14_08190 c694728a7174ae05d6e46f0daef90bae 273 SUPERFAMILY SSF53686 3 270 5.63E-64 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_08190 c694728a7174ae05d6e46f0daef90bae 273 Gene3D G3DSA:3.40.50.1100 19 120 1.1E-70 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 459 1.2E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 443 450 1.8E-15 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 1.8E-15 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 1.8E-15 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 1.8E-15 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 SUPERFAMILY SSF51971 158 408 2.88E-71 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 3.3E-22 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 3.3E-22 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 3.3E-22 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 428 450 3.3E-22 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 3.3E-22 T 23-10-2018 A3L14_09930 a788da5d03175e25696774b134d53492 481 Gene3D G3DSA:1.10.1060.10 14 151 6.0E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_09930 a788da5d03175e25696774b134d53492 481 SUPERFAMILY SSF46548 9 168 1.67E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_09930 a788da5d03175e25696774b134d53492 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 474 3.1E-220 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L14_09930 a788da5d03175e25696774b134d53492 481 Gene3D G3DSA:3.50.50.60 294 481 4.5E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09930 a788da5d03175e25696774b134d53492 481 Gene3D G3DSA:3.50.50.60 155 285 2.6E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09930 a788da5d03175e25696774b134d53492 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 4.7E-39 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L14_04205 d065ce1726096b17a3dc90c067e17cb9 421 SUPERFAMILY SSF50475 5 279 8.24E-63 T 23-10-2018 A3L14_04205 d065ce1726096b17a3dc90c067e17cb9 421 Gene3D G3DSA:3.40.1670.10 296 408 4.0E-37 T 23-10-2018 A3L14_04205 d065ce1726096b17a3dc90c067e17cb9 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 385 2.8E-97 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L14_04205 d065ce1726096b17a3dc90c067e17cb9 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 409 1.6E-112 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L14_04205 d065ce1726096b17a3dc90c067e17cb9 421 SUPERFAMILY SSF143968 282 419 9.15E-42 T 23-10-2018 A3L14_07115 4ddc8f0c84540f3bcc026e08cc23e792 299 Pfam PF00892 EamA-like transporter family 6 152 1.7E-28 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_07115 4ddc8f0c84540f3bcc026e08cc23e792 299 Pfam PF00892 EamA-like transporter family 165 298 3.7E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_07115 4ddc8f0c84540f3bcc026e08cc23e792 299 SUPERFAMILY SSF103481 75 153 9.68E-16 T 23-10-2018 A3L14_07115 4ddc8f0c84540f3bcc026e08cc23e792 299 SUPERFAMILY SSF103481 206 297 8.5E-8 T 23-10-2018 A3L14_10400 22752333e97faf7b8c37d780b6c3fc7a 324 Gene3D G3DSA:1.10.8.300 206 315 1.1E-30 T 23-10-2018 A3L14_10400 22752333e97faf7b8c37d780b6c3fc7a 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 1.1E-62 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L14_10400 22752333e97faf7b8c37d780b6c3fc7a 324 SUPERFAMILY SSF52540 6 290 6.28E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10400 22752333e97faf7b8c37d780b6c3fc7a 324 PIRSF PIRSF002849 1 320 3.8E-125 T 23-10-2018 A3L14_10400 22752333e97faf7b8c37d780b6c3fc7a 324 Gene3D G3DSA:3.40.50.300 22 188 3.0E-44 T 23-10-2018 A3L14_07740 acdbce3d063c75326d4fcadf958af8c1 238 SMART SM00849 31 220 6.1E-42 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_07740 acdbce3d063c75326d4fcadf958af8c1 238 Gene3D G3DSA:3.60.15.10 4 233 2.0E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_07740 acdbce3d063c75326d4fcadf958af8c1 238 SUPERFAMILY SSF56281 10 235 2.44E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_07740 acdbce3d063c75326d4fcadf958af8c1 238 Pfam PF00753 Metallo-beta-lactamase superfamily 31 220 2.6E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_09690 7c99a8884db1d13ac3833c1517cc7da5 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 7.9E-80 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L14_09690 7c99a8884db1d13ac3833c1517cc7da5 539 Pfam PF00474 Sodium:solute symporter family 33 435 1.7E-86 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L14_09690 7c99a8884db1d13ac3833c1517cc7da5 539 Gene3D G3DSA:1.20.1730.10 22 517 1.9E-93 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.738 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 Gene3D G3DSA:3.30.2320.30 100 203 7.3E-20 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 SUPERFAMILY SSF160527 81 203 9.94E-27 T 23-10-2018 A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 Gene3D G3DSA:1.20.5.620 18 98 1.3E-26 T 23-10-2018 A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 SUPERFAMILY SSF81573 13 63 2.35E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L14_00710 d2093361f5f5741ee1cdd4e811316668 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 7.3E-41 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_02005 8444ba64be62ac7c70765bf3cf01aacc 78 SUPERFAMILY SSF143011 5 73 7.85E-14 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_02005 8444ba64be62ac7c70765bf3cf01aacc 78 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 75 1.4E-6 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A3L14_02005 8444ba64be62ac7c70765bf3cf01aacc 78 Gene3D G3DSA:3.30.2310.20 2 76 1.5E-17 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_06595 767f53edb7c7bd001a1eb9d1065e2b2a 101 Gene3D G3DSA:3.30.460.10 1 100 5.6E-23 T 23-10-2018 A3L14_06595 767f53edb7c7bd001a1eb9d1065e2b2a 101 SUPERFAMILY SSF81301 8 90 1.15E-17 T 23-10-2018 A3L14_06595 767f53edb7c7bd001a1eb9d1065e2b2a 101 Pfam PF01909 Nucleotidyltransferase domain 8 79 6.7E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_06045 d5e9c4bdc3b1415779cda612d9e45c44 248 SMART SM00986 104 233 5.0E-9 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_06045 d5e9c4bdc3b1415779cda612d9e45c44 248 SMART SM00987 104 233 5.0E-9 T 23-10-2018 A3L14_06045 d5e9c4bdc3b1415779cda612d9e45c44 248 SUPERFAMILY SSF52141 99 224 1.77E-22 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_06045 d5e9c4bdc3b1415779cda612d9e45c44 248 Pfam PF03167 Uracil DNA glycosylase superfamily 109 227 8.5E-20 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_06045 d5e9c4bdc3b1415779cda612d9e45c44 248 Gene3D G3DSA:3.40.470.10 62 242 1.5E-23 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 SUPERFAMILY SSF52141 265 421 1.83E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 SUPERFAMILY SSF88802 247 500 1.9E-17 T 23-10-2018 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 SMART SM00359 502 568 1.8E-5 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 SUPERFAMILY SSF88697 511 566 8.52E-12 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 SUPERFAMILY SSF51713 1 242 1.7E-21 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 3.2E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 Gene3D G3DSA:3.40.50.10630 252 423 1.5E-46 T 23-10-2018 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 Gene3D G3DSA:2.30.130.10 502 568 1.1E-23 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_10755 1ca26e66c34443524b70f6c7030ad40d 568 Pfam PF01472 PUA domain 511 566 1.2E-8 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 SUPERFAMILY SSF54197 154 314 1.01E-42 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 PIRSF PIRSF000808 1 314 4.7E-109 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 5 310 5.7E-52 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 159 311 1.6E-15 T 23-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 Gene3D G3DSA:3.30.428.10 3 309 1.9E-92 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 3 151 1.3E-25 T 23-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 SUPERFAMILY SSF54197 1 151 6.81E-46 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_04355 e79307e675992deef4ca99df07e7eb52 327 Gene3D G3DSA:3.30.428.10 31 150 1.9E-92 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_05425 d2d1f26c60b948a799258acde3e70f05 216 Pfam PF00156 Phosphoribosyl transferase domain 16 152 3.6E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_05425 d2d1f26c60b948a799258acde3e70f05 216 Gene3D G3DSA:3.40.50.2020 6 169 4.1E-42 T 23-10-2018 A3L14_05425 d2d1f26c60b948a799258acde3e70f05 216 SUPERFAMILY SSF53271 7 159 4.59E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_00620 e7db9b3c29581269c15f0ee39960f219 309 Pfam PF00717 Peptidase S24-like 30 80 6.7E-6 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L14_00620 e7db9b3c29581269c15f0ee39960f219 309 SUPERFAMILY SSF51306 27 128 7.59E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L14_00620 e7db9b3c29581269c15f0ee39960f219 309 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 30 45 2.3E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_00620 e7db9b3c29581269c15f0ee39960f219 309 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 91 102 2.3E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_00620 e7db9b3c29581269c15f0ee39960f219 309 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 150 2.5E-29 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Gene3D G3DSA:3.30.930.10 13 284 9.4E-86 T 23-10-2018 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Gene3D G3DSA:3.40.50.800 285 403 7.5E-36 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 SUPERFAMILY SSF55681 12 278 1.15E-76 T 23-10-2018 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 SMART SM00946 412 483 5.0E-23 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 483 41.11 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 11 483 2.3E-178 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 SUPERFAMILY SSF52954 280 404 6.19E-37 T 23-10-2018 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 SUPERFAMILY SSF64586 407 483 2.75E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 101 273 8.5E-24 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Pfam PF03129 Anticodon binding domain 291 385 1.8E-22 T 23-10-2018 IPR004154 Anticodon-binding A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 413 483 1.4E-14 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 Gene3D G3DSA:3.30.110.30 406 482 5.7E-18 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 137 145 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 66 84 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L14_05225 336f778b98d5d21e3da1f98ad1efba61 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 107 118 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L14_08785 23971df4f2bff5b366cd8fce1af2be2c 187 SUPERFAMILY SSF55469 1 187 1.22E-45 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_08785 23971df4f2bff5b366cd8fce1af2be2c 187 Gene3D G3DSA:3.40.109.10 1 185 1.1E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_08785 23971df4f2bff5b366cd8fce1af2be2c 187 Pfam PF00881 Nitroreductase family 8 165 2.1E-27 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_07635 5f3ea3857de05ac966a22cf398bebeab 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 4.9E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L14_07635 5f3ea3857de05ac966a22cf398bebeab 152 Gene3D G3DSA:3.30.479.10 12 150 3.8E-32 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L14_07635 5f3ea3857de05ac966a22cf398bebeab 152 SUPERFAMILY SSF55620 10 150 1.0E-34 T 23-10-2018 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 SUPERFAMILY SSF55486 8 498 2.08E-109 T 23-10-2018 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PIRSF PIRSF006615 5 498 2.7E-195 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 Gene3D G3DSA:1.10.1370.30 1 498 4.8E-193 T 23-10-2018 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 449 467 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 7.9E-85 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_00355 33a305ec3dc99c41c6fafefdb7d42c7e 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 497 2.1E-102 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 SUPERFAMILY SSF53218 12 168 3.93E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 PIRSF PIRSF006443 1 171 5.1E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 SMART SM00852 17 165 1.3E-27 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 Pfam PF00994 Probable molybdopterin binding domain 17 159 1.2E-35 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 8.4E-35 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_06115 584cb42b40c6c8a2ffa43f270116c276 171 Gene3D G3DSA:3.40.980.10 12 170 9.2E-47 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_10495 34c9bcdeb3c96db7b48faa58107f49ed 174 SUPERFAMILY SSF117457 3 172 4.32E-52 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L14_10495 34c9bcdeb3c96db7b48faa58107f49ed 174 Pfam PF05683 Fumarase C-terminus 3 172 9.2E-41 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L14_10495 34c9bcdeb3c96db7b48faa58107f49ed 174 Gene3D G3DSA:3.20.130.10 1 174 2.0E-66 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L14_10495 34c9bcdeb3c96db7b48faa58107f49ed 174 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 13 173 3.3E-55 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L14_06050 f49ca9088f57a4dde19daed3285fc7f0 216 Gene3D G3DSA:3.90.1490.10 120 213 1.5E-14 T 23-10-2018 A3L14_06050 f49ca9088f57a4dde19daed3285fc7f0 216 SUPERFAMILY SSF52402 5 211 2.22E-50 T 23-10-2018 A3L14_06050 f49ca9088f57a4dde19daed3285fc7f0 216 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 7 209 5.5E-34 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_06050 f49ca9088f57a4dde19daed3285fc7f0 216 Gene3D G3DSA:3.40.50.620 2 119 3.3E-14 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_06050 f49ca9088f57a4dde19daed3285fc7f0 216 Pfam PF01902 Diphthamide synthase 7 211 1.0E-35 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L14_11230 735bf8cef1a39399b2c15b210a15ea5a 70 Pfam PF01938 TRAM domain 14 70 5.5E-15 T 23-10-2018 IPR002792 TRAM domain A3L14_11230 735bf8cef1a39399b2c15b210a15ea5a 70 Gene3D G3DSA:2.40.50.140 5 70 4.1E-26 T 23-10-2018 A3L14_11230 735bf8cef1a39399b2c15b210a15ea5a 70 SUPERFAMILY SSF50249 10 70 1.14E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 SUPERFAMILY SSF53323 8 222 1.31E-37 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 Gene3D G3DSA:3.40.920.10 5 186 9.8E-25 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 444 5.2E-57 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 1.4E-30 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 564 1.9E-203 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 SUPERFAMILY SSF52922 463 566 3.28E-12 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 Gene3D G3DSA:3.40.50.970 189 386 5.6E-71 T 23-10-2018 A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 SUPERFAMILY SSF52518 201 449 4.91E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_07270 f0184f4b71152aa79510acbaf9a6b2bd 570 Gene3D G3DSA:3.40.50.920 459 570 1.9E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 SUPERFAMILY SSF56042 545 704 4.64E-33 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 SUPERFAMILY SSF55326 376 534 2.88E-48 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Gene3D G3DSA:3.90.650.10 12 339 1.4E-121 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 184 339 5.5E-38 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 552 680 8.5E-20 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 704 5.3E-287 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Gene3D G3DSA:3.30.1330.10 362 535 4.6E-54 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 252.791 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 SUPERFAMILY SSF56042 184 400 1.47E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Gene3D G3DSA:3.30.1330.10 27 175 1.4E-121 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Gene3D G3DSA:3.90.650.10 544 709 5.5E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 428 532 4.7E-21 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 2.1E-24 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 SUPERFAMILY SSF55326 19 178 5.53E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_01425 19ca0025080aafe843c25d5b1cc7f413 713 PIRSF PIRSF001587 1 712 5.1E-277 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_04730 9c622b79438ea2fcad7d2c690cd47efa 154 SUPERFAMILY SSF48452 51 139 1.18E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_04730 9c622b79438ea2fcad7d2c690cd47efa 154 Gene3D G3DSA:1.25.40.10 2 49 1.5E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_04730 9c622b79438ea2fcad7d2c690cd47efa 154 Gene3D G3DSA:1.25.40.10 50 153 3.1E-21 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 1.5E-36 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Gene3D G3DSA:2.40.30.10 319 410 1.2E-33 T 23-10-2018 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 SUPERFAMILY SSF52540 4 209 4.07E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01800 010fbe323a4a6450dad92125572acadd 410 SUPERFAMILY SSF50447 204 316 1.48E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_01800 010fbe323a4a6450dad92125572acadd 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 195 1.6E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.367 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Gene3D G3DSA:2.40.30.10 204 318 4.3E-47 T 23-10-2018 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 SUPERFAMILY SSF50465 317 409 1.98E-32 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 2.0E-10 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Gene3D G3DSA:3.40.50.300 3 203 6.7E-68 T 23-10-2018 A3L14_01800 010fbe323a4a6450dad92125572acadd 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 7.7E-206 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L14_01800 010fbe323a4a6450dad92125572acadd 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 1.6E-30 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A3L14_03575 cd9cfd0d104e52425be6cc97edfd39d9 133 Hamap MF_01095 UPF0292 protein . 3 123 32.44 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A3L14_03575 cd9cfd0d104e52425be6cc97edfd39d9 133 Gene3D G3DSA:3.40.1360.10 3 116 1.2E-22 T 23-10-2018 A3L14_03575 cd9cfd0d104e52425be6cc97edfd39d9 133 Pfam PF01751 Toprim domain 25 86 3.4E-6 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03575 cd9cfd0d104e52425be6cc97edfd39d9 133 SUPERFAMILY SSF110455 19 99 4.05E-6 T 23-10-2018 A3L14_03575 cd9cfd0d104e52425be6cc97edfd39d9 133 SMART SM00493 20 90 1.2E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L14_08515 2a37bd80a64d4b9097738ddae5bd5303 143 SUPERFAMILY SSF52242 5 134 4.19E-48 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L14_08515 2a37bd80a64d4b9097738ddae5bd5303 143 Pfam PF02310 B12 binding domain 8 120 1.5E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L14_08515 2a37bd80a64d4b9097738ddae5bd5303 143 Gene3D G3DSA:3.40.50.280 1 142 1.6E-56 T 23-10-2018 A3L14_08515 2a37bd80a64d4b9097738ddae5bd5303 143 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 1.1E-59 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L14_05125 bbeff2990a064508136728d017af1667 616 Gene3D G3DSA:3.40.50.1980 469 596 2.6E-35 T 23-10-2018 A3L14_05125 bbeff2990a064508136728d017af1667 616 Gene3D G3DSA:3.40.50.1980 197 324 5.8E-35 T 23-10-2018 A3L14_05125 bbeff2990a064508136728d017af1667 616 Pfam PF01497 Periplasmic binding protein 353 571 7.0E-41 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L14_05125 bbeff2990a064508136728d017af1667 616 Pfam PF01497 Periplasmic binding protein 82 300 3.6E-35 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L14_05125 bbeff2990a064508136728d017af1667 616 Gene3D G3DSA:3.40.50.1980 60 181 1.7E-32 T 23-10-2018 A3L14_05125 bbeff2990a064508136728d017af1667 616 Gene3D G3DSA:3.40.50.1980 335 465 2.0E-36 T 23-10-2018 A3L14_05125 bbeff2990a064508136728d017af1667 616 SUPERFAMILY SSF53807 337 600 3.81E-74 T 23-10-2018 A3L14_05125 bbeff2990a064508136728d017af1667 616 SUPERFAMILY SSF53807 66 329 1.02E-68 T 23-10-2018 A3L14_10955 a6cc1146b9805bd1a6460e23d54bf3ad 166 SUPERFAMILY SSF46785 86 155 2.33E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10955 a6cc1146b9805bd1a6460e23d54bf3ad 166 Gene3D G3DSA:1.10.10.10 73 150 6.5E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10955 a6cc1146b9805bd1a6460e23d54bf3ad 166 Pfam PF08279 HTH domain 88 128 2.3E-6 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L14_04020 c85639b6f608caf5f25d796eb9643261 508 Gene3D G3DSA:2.60.40.10 305 382 3.2E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_04020 c85639b6f608caf5f25d796eb9643261 508 SUPERFAMILY SSF49373 310 369 1.14E-5 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A3L14_04020 c85639b6f608caf5f25d796eb9643261 508 SUPERFAMILY SSF49464 245 296 4.32E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 Gene3D G3DSA:3.30.420.40 4 298 5.4E-113 T 23-10-2018 A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 Pfam PF00814 Glycoprotease family 22 292 1.4E-95 T 23-10-2018 IPR000905 Gcp-like domain A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 Gene3D G3DSA:3.30.420.40 122 278 5.4E-113 T 23-10-2018 A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 3.3E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 1.0E-98 T 23-10-2018 IPR017861 Kae1/TsaD family A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.14 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 4.5E-151 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A3L14_00055 f4215d49fe09d7ebf99d081459dd5f2b 325 SUPERFAMILY SSF53067 1 292 2.78E-35 T 23-10-2018 A3L14_10070 04c9bde4a781a3dd163407c28dac8120 158 SUPERFAMILY SSF56784 2 143 1.05E-19 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_10070 04c9bde4a781a3dd163407c28dac8120 158 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 153 1.1E-27 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A3L14_10070 04c9bde4a781a3dd163407c28dac8120 158 Pfam PF03031 NLI interacting factor-like phosphatase 2 156 5.1E-11 T 23-10-2018 IPR004274 FCP1 homology domain A3L14_10070 04c9bde4a781a3dd163407c28dac8120 158 Gene3D G3DSA:3.40.50.1000 1 157 9.1E-29 T 23-10-2018 IPR023214 HAD superfamily A3L14_10070 04c9bde4a781a3dd163407c28dac8120 158 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 2 131 8.5E-17 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 Gene3D G3DSA:3.90.940.20 1 82 3.8E-37 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 SUPERFAMILY SSF55287 7 80 2.35E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.853 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 4.5E-32 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03425 a02ee85f6a54761f951c0bc35171bf86 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 13 79 1.0E-22 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_07570 a719eb9529680f05970f90fceba1c655 566 Pfam PF10102 Domain of unknown function (DUF2341) 183 263 2.7E-7 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 3.1E-242 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 SUPERFAMILY SSF52029 212 378 1.28E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 SUPERFAMILY SSF48592 17 524 1.83E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 SUPERFAMILY SSF54849 146 404 2.41E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 Gene3D G3DSA:3.50.7.10 218 369 4.5E-212 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 Gene3D G3DSA:3.30.260.10 147 405 4.5E-212 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 Gene3D G3DSA:1.10.560.10 28 522 4.5E-212 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L14_01265 b0bd59b2058af3913e5a4c8f9e2ac84d 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.9E-182 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 SUPERFAMILY SSF49464 632 703 3.02E-5 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 Gene3D G3DSA:2.60.40.10 789 868 6.4E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 Gene3D G3DSA:3.10.620.30 179 323 3.0E-21 T 23-10-2018 A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 SMART SM00460 248 316 6.9E-17 T 23-10-2018 IPR002931 Transglutaminase-like A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 Pfam PF01841 Transglutaminase-like superfamily 202 314 2.0E-23 T 23-10-2018 IPR002931 Transglutaminase-like A3L14_10390 1083ba2779a817700c63f8a220ceeb76 1075 SUPERFAMILY SSF54001 193 320 5.33E-26 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 SUPERFAMILY SSF51905 5 344 2.06E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 436 2.6E-181 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 Gene3D G3DSA:3.50.50.60 5 314 6.6E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 SUPERFAMILY SSF55424 320 438 8.25E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 301 1.6E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 427 9.8E-19 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 Gene3D G3DSA:3.50.50.60 320 441 3.7E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 Gene3D G3DSA:3.50.50.60 43 241 6.6E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 1.5E-22 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 1.5E-22 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 1.5E-22 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 1.5E-22 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.5E-22 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.8E-27 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.8E-27 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 3.8E-27 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.8E-27 T 23-10-2018 A3L14_03115 00a4df1cac1a633e91c8d28d02a4b22f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.8E-27 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 1.4E-235 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 SUPERFAMILY SSF75553 483 677 5.49E-50 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 SMART SM00968 520 632 2.0E-41 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 SUPERFAMILY SSF57997 712 935 2.42E-5 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:3.40.50.300 1010 1181 1.9E-59 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:3.40.50.300 2 235 1.1E-60 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:3.30.70.1620 581 658 2.9E-44 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:1.20.1060.20 506 661 2.9E-44 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 SUPERFAMILY SSF52540 1 1168 4.51E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 PIRSF PIRSF005719 1 1168 2.4E-281 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.294 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 631 1.4E-31 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:1.20.5.340 774 896 4.4E-7 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Gene3D G3DSA:1.20.5.340 368 488 1.0E-5 T 23-10-2018 A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 2.1E-68 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L14_08495 1ef40143a6a8af4c982c1068cdde16a3 1188 SUPERFAMILY SSF57997 379 512 1.24E-6 T 23-10-2018 A3L14_02435 4b9c8d810b86db1efd85d558d76e74c8 388 Gene3D G3DSA:1.20.1250.20 207 382 1.2E-8 T 23-10-2018 A3L14_02435 4b9c8d810b86db1efd85d558d76e74c8 388 SUPERFAMILY SSF103473 9 378 5.49E-28 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_02435 4b9c8d810b86db1efd85d558d76e74c8 388 Pfam PF07690 Major Facilitator Superfamily 12 307 7.3E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_02435 4b9c8d810b86db1efd85d558d76e74c8 388 Gene3D G3DSA:1.20.1250.20 1 199 4.4E-14 T 23-10-2018 A3L14_02080 56d63e56d73ce9cbf521e09f5cc44fd8 132 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 10 128 3.9E-9 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 SUPERFAMILY SSF55811 30 167 2.3E-35 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 Pfam PF00293 NUDIX domain 45 164 1.7E-23 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 Gene3D G3DSA:3.90.79.10 40 168 4.6E-43 T 23-10-2018 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 PRINTS PR00502 NUDIX hydrolase family signature 70 84 9.1E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L14_09200 2d5604d6b0914486fbcc12696a2716fb 169 PRINTS PR00502 NUDIX hydrolase family signature 84 99 9.1E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L14_03140 5fbeaca49f35555796908d6933d4db50 398 PIRSF PIRSF005572 15 398 1.4E-50 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A3L14_03140 5fbeaca49f35555796908d6933d4db50 398 Gene3D G3DSA:3.90.1150.10 7 387 6.2E-145 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_03140 5fbeaca49f35555796908d6933d4db50 398 Pfam PF00266 Aminotransferase class-V 18 386 2.3E-138 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L14_03140 5fbeaca49f35555796908d6933d4db50 398 SUPERFAMILY SSF53383 5 397 3.85E-119 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_03140 5fbeaca49f35555796908d6933d4db50 398 Gene3D G3DSA:3.40.640.10 29 287 6.2E-145 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 SMART SM00863 702 745 2.8E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Pfam PF02272 DHHA1 domain 782 910 5.0E-18 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 SUPERFAMILY SSF55186 603 752 1.06E-48 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 702 744 3.7E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 911 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Gene3D G3DSA:3.30.54.20 675 726 1.0E-28 T 23-10-2018 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Gene3D G3DSA:3.10.310.40 813 913 4.8E-20 T 23-10-2018 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 SUPERFAMILY SSF55681 57 264 1.37E-57 T 23-10-2018 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 893 7.3E-237 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Pfam PF01411 tRNA synthetases class II (A) 61 603 1.7E-160 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Gene3D G3DSA:3.30.980.10 605 674 3.7E-22 T 23-10-2018 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.6E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Gene3D G3DSA:3.30.930.10 1 260 1.1E-113 T 23-10-2018 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 910 24.202 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 SUPERFAMILY SSF50447 512 599 9.53E-20 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 SUPERFAMILY SSF101353 310 501 2.88E-48 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L14_00630 7d643da5287e74969b8411ddb2b998f1 913 Gene3D G3DSA:2.40.30.130 502 599 7.0E-38 T 23-10-2018 A3L14_05245 52429304c327b712f70a37b2922d316f 142 SUPERFAMILY SSF88723 6 130 1.88E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05245 52429304c327b712f70a37b2922d316f 142 Gene3D G3DSA:3.40.50.1010 10 129 3.7E-11 T 23-10-2018 A3L14_05245 52429304c327b712f70a37b2922d316f 142 SMART SM00670 8 120 3.6E-6 T 23-10-2018 IPR002716 PIN domain A3L14_05245 52429304c327b712f70a37b2922d316f 142 Pfam PF01850 PIN domain 11 123 1.7E-12 T 23-10-2018 IPR002716 PIN domain A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 SUPERFAMILY SSF53218 181 322 4.97E-35 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 SUPERFAMILY SSF63882 7 181 6.02E-58 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Gene3D G3DSA:3.40.980.10 19 314 1.2E-109 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Gene3D G3DSA:2.40.340.10 320 396 5.6E-27 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Pfam PF03454 MoeA C-terminal region (domain IV) 330 395 9.5E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Gene3D G3DSA:3.90.105.10 27 181 1.2E-109 T 23-10-2018 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Gene3D G3DSA:2.170.190.11 50 148 1.2E-109 T 23-10-2018 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 1.5E-47 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 5.4E-18 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 SUPERFAMILY SSF63867 327 396 3.27E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06120 f26b70db4dd0322ef7f7c9517f89af3f 396 SMART SM00852 186 317 4.1E-30 T 23-10-2018 IPR001453 MoaB/Mog domain A3L14_03225 c90b11b0de827801cb5c67a9484b8087 59 Pfam PF07650 KH domain 7 56 1.7E-5 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03225 c90b11b0de827801cb5c67a9484b8087 59 Gene3D G3DSA:3.30.300.20 5 58 8.2E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03225 c90b11b0de827801cb5c67a9484b8087 59 SUPERFAMILY SSF54814 14 57 2.57E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 46.459 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 SUPERFAMILY SSF52374 4 368 7.51E-90 T 23-10-2018 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 378 9.0E-106 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 Gene3D G3DSA:1.10.240.10 256 380 1.3E-45 T 23-10-2018 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 2.7E-26 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 1.4E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 1.4E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 1.4E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 1.4E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L14_00230 a53414a6e0e42471f1bfbcd2bd17c2c7 384 Gene3D G3DSA:3.40.50.620 1 255 1.0E-102 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 2.0E-82 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 SUPERFAMILY SSF51366 2 214 4.71E-45 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 Gene3D G3DSA:3.20.20.70 1 208 3.8E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 SMART SM00934 2 203 7.9E-45 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 Pfam PF01380 SIS domain 246 347 8.8E-20 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 3.0E-73 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 3.3E-27 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 Gene3D G3DSA:3.40.50.10490 213 406 4.4E-57 T 23-10-2018 A3L14_03835 9bdb76c7b233a6f63ae778684f4538b9 406 SUPERFAMILY SSF53697 215 404 3.64E-38 T 23-10-2018 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 2.6E-21 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 421 1.8E-142 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 Pfam PF04055 Radical SAM superfamily 142 314 2.7E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 Gene3D G3DSA:3.40.50.12160 2 124 3.1E-25 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 Pfam PF01938 TRAM domain 366 424 8.6E-9 T 23-10-2018 IPR002792 TRAM domain A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 SUPERFAMILY SSF102114 128 356 3.4E-54 T 23-10-2018 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 Gene3D G3DSA:3.80.30.20 138 369 2.4E-75 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 4.6E-129 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A3L14_11225 6d9c0eefc65a0bdd51f45fe995001d32 425 SMART SM00729 138 355 2.1E-61 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 Gene3D G3DSA:3.30.1490.10 70 128 1.5E-27 T 23-10-2018 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 SUPERFAMILY SSF56047 3 130 9.68E-40 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.402 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 Gene3D G3DSA:3.30.1370.30 1 69 2.6E-32 T 23-10-2018 A3L14_02555 b878d4e418bc1d8868323fd849363821 130 Pfam PF00410 Ribosomal protein S8 5 130 4.4E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04530 f13c8829cc5d62d747958a0ff5459653 169 Pfam PF01230 HIT domain 35 125 1.2E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L14_04530 f13c8829cc5d62d747958a0ff5459653 169 Gene3D G3DSA:3.30.428.10 1 163 4.2E-59 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_04530 f13c8829cc5d62d747958a0ff5459653 169 SUPERFAMILY SSF54197 1 154 4.54E-47 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_03875 91bd664f90020d73ae216c36c088af7e 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 4.2E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L14_03875 91bd664f90020d73ae216c36c088af7e 118 SUPERFAMILY SSF102462 3 118 1.1E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L14_03875 91bd664f90020d73ae216c36c088af7e 118 Gene3D G3DSA:3.40.1490.10 1 118 3.8E-48 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L14_03875 91bd664f90020d73ae216c36c088af7e 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.804 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A3L14_03875 91bd664f90020d73ae216c36c088af7e 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 1.6E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L14_00435 4a3caeb062aadcd12d7fbfdfaa673c79 354 Pfam PF13579 Glycosyl transferase 4-like domain 12 170 9.4E-17 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L14_00435 4a3caeb062aadcd12d7fbfdfaa673c79 354 Gene3D G3DSA:3.40.50.2000 11 179 9.9E-22 T 23-10-2018 A3L14_00435 4a3caeb062aadcd12d7fbfdfaa673c79 354 Gene3D G3DSA:3.40.50.2000 180 298 4.9E-11 T 23-10-2018 A3L14_00435 4a3caeb062aadcd12d7fbfdfaa673c79 354 SUPERFAMILY SSF53756 13 349 6.8E-33 T 23-10-2018 A3L14_07925 dccaa9ab5c4989094a4046bfe66c7e42 320 Gene3D G3DSA:3.40.50.150 123 311 4.2E-29 T 23-10-2018 A3L14_07925 dccaa9ab5c4989094a4046bfe66c7e42 320 Pfam PF13847 Methyltransferase domain 157 264 1.0E-14 T 23-10-2018 IPR025714 Methyltransferase domain A3L14_07925 dccaa9ab5c4989094a4046bfe66c7e42 320 SUPERFAMILY SSF53335 127 302 1.15E-29 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06985 bdca480e2d2cd0ddf20f5c7ab3e57867 246 Gene3D G3DSA:3.40.50.300 3 243 1.2E-69 T 23-10-2018 A3L14_06985 bdca480e2d2cd0ddf20f5c7ab3e57867 246 Pfam PF00005 ABC transporter 26 181 4.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06985 bdca480e2d2cd0ddf20f5c7ab3e57867 246 SUPERFAMILY SSF52540 5 235 3.59E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06985 bdca480e2d2cd0ddf20f5c7ab3e57867 246 SMART SM00382 34 229 6.6E-20 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06985 bdca480e2d2cd0ddf20f5c7ab3e57867 246 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 6.1E-211 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 SUPERFAMILY SSF52283 5 421 2.55E-102 T 23-10-2018 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 8.4E-34 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 SUPERFAMILY SSF51735 188 350 4.43E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Gene3D G3DSA:3.40.50.1480 9 410 4.9E-176 T 23-10-2018 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 PIRSF PIRSF001109 1 421 6.5E-196 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Gene3D G3DSA:3.40.50.720 190 349 4.9E-176 T 23-10-2018 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.231 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 416 3.7E-29 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 4.6E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 SMART SM00996 6 420 2.0E-138 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 SMART SM00997 188 349 9.3E-111 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_08995 fd568330cb3a07f4f636ab8b14d3a706 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 SUPERFAMILY SSF161070 4 498 9.81E-110 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 Pfam PF00209 Sodium:neurotransmitter symporter family 161 463 1.3E-30 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 3.2E-24 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 397 417 1.7E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.7E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 320 339 1.7E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_03015 592ec0d4a6fb38cba0ce5752ec299add 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.7E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 27.856 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 SMART SM01016 12 95 3.2E-21 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Gene3D G3DSA:3.40.50.620 122 523 9.7E-157 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 SUPERFAMILY SSF52374 121 513 4.64E-79 T 23-10-2018 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 SMART SM00836 520 642 4.1E-48 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 SUPERFAMILY SSF55190 13 116 1.44E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Pfam PF05746 DALR anticodon binding domain 520 642 3.2E-36 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 SUPERFAMILY SSF47323 516 642 3.79E-34 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Gene3D G3DSA:3.30.1360.70 7 121 4.4E-33 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Pfam PF00750 tRNA synthetases class I (R) 390 492 9.7E-11 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Pfam PF00750 tRNA synthetases class I (R) 105 361 2.1E-24 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 7.4E-15 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 368 3.9E-80 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L14_04940 3d2a3593885ad9db76560ac6631acf76 642 Gene3D G3DSA:1.10.730.10 524 642 4.4E-41 T 23-10-2018 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Pfam PF02926 THUMP domain 28 167 1.1E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 SUPERFAMILY SSF52402 177 336 8.6E-49 T 23-10-2018 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Gene3D G3DSA:3.30.70.1510 1 83 7.9E-33 T 23-10-2018 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 SMART SM00981 73 167 1.3E-20 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 366 1.6E-103 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Gene3D G3DSA:3.30.2300.10 84 165 2.5E-29 T 23-10-2018 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 369 9.8E-65 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 SUPERFAMILY SSF143437 1 175 3.14E-48 T 23-10-2018 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 380 126.667 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L14_08215 e2ec4ed3ab7e997472e2fc1711b8b370 380 Gene3D G3DSA:3.40.50.620 177 375 1.2E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 1.3E-10 T 23-10-2018 A3L14_04855 635b8be4f85f19062dda76f71313392a 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 5.8E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01115 89fab8af13c1766f9f133e5ec06fc89d 295 SUPERFAMILY SSF53448 2 235 1.07E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01115 89fab8af13c1766f9f133e5ec06fc89d 295 Gene3D G3DSA:3.90.550.10 2 222 3.2E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01115 89fab8af13c1766f9f133e5ec06fc89d 295 Pfam PF00535 Glycosyl transferase family 2 5 123 3.8E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_09005 39eca68d8e806bf0213f7d69860383fe 185 Pfam PF13023 HD domain 11 153 1.2E-31 T 23-10-2018 IPR006674 HD domain A3L14_09005 39eca68d8e806bf0213f7d69860383fe 185 Gene3D G3DSA:1.10.3210.10 1 183 2.4E-62 T 23-10-2018 A3L14_09005 39eca68d8e806bf0213f7d69860383fe 185 SUPERFAMILY SSF109604 2 176 3.66E-43 T 23-10-2018 A3L14_09005 39eca68d8e806bf0213f7d69860383fe 185 SMART SM00471 28 146 2.0E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L14_06030 96ee66794ea22187eef8097b004c36d8 248 Gene3D G3DSA:3.40.50.150 1 149 5.9E-49 T 23-10-2018 A3L14_06030 96ee66794ea22187eef8097b004c36d8 248 SUPERFAMILY SSF53335 1 244 3.14E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06030 96ee66794ea22187eef8097b004c36d8 248 Pfam PF13649 Methyltransferase domain 45 139 1.2E-25 T 23-10-2018 A3L14_06030 96ee66794ea22187eef8097b004c36d8 248 Gene3D G3DSA:2.20.25.110 150 209 1.7E-35 T 23-10-2018 A3L14_08645 0445d015845719ce27a1bf43e8cf5efd 145 Pfam PF06146 Phosphate-starvation-inducible E 57 122 2.8E-13 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 SMART SM00662 14 254 1.7E-82 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 5.1E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Gene3D G3DSA:3.30.70.3110 157 218 7.7E-95 T 23-10-2018 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 SUPERFAMILY SSF55257 3 257 2.85E-29 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Gene3D G3DSA:2.170.120.12 40 147 7.7E-95 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Gene3D G3DSA:3.30.1360.10 7 251 7.7E-95 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.32 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 SUPERFAMILY SSF56553 39 149 4.97E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_02670 784bf234cc8a692111fe1205c6890d5a 261 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 1.3E-27 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03310 d3f77106d8f23fc04d840456fc63827c 65 Gene3D G3DSA:2.20.25.100 11 65 6.4E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A3L14_03310 d3f77106d8f23fc04d840456fc63827c 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03310 d3f77106d8f23fc04d840456fc63827c 65 Pfam PF01667 Ribosomal protein S27 11 64 2.3E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03310 d3f77106d8f23fc04d840456fc63827c 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.447 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03310 d3f77106d8f23fc04d840456fc63827c 65 SUPERFAMILY SSF57829 11 65 3.66E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 Gene3D G3DSA:3.40.50.150 154 450 1.2E-79 T 23-10-2018 A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 SUPERFAMILY SSF53335 148 450 3.29E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 2.7E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 1.3E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 1.3E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 1.3E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 1.3E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 1.3E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 Pfam PF01029 NusB family 10 133 6.8E-19 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 Gene3D G3DSA:1.10.940.10 6 150 8.0E-14 T 23-10-2018 IPR035926 NusB-like superfamily A3L14_01975 a3ac9403e99cac94427b805342f5b42b 452 SUPERFAMILY SSF48013 9 163 2.35E-23 T 23-10-2018 IPR035926 NusB-like superfamily A3L14_02550 4520627ba3242f5f7641c61ce56aea22 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02550 4520627ba3242f5f7641c61ce56aea22 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.461 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A3L14_02550 4520627ba3242f5f7641c61ce56aea22 56 Gene3D G3DSA:4.10.830.10 1 56 2.2E-20 T 23-10-2018 A3L14_02550 4520627ba3242f5f7641c61ce56aea22 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 1.9E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 Gene3D G3DSA:3.40.630.10 14 336 6.1E-61 T 23-10-2018 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 SUPERFAMILY SSF53187 8 343 5.71E-41 T 23-10-2018 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 Pfam PF07687 Peptidase dimerisation domain 152 254 3.7E-7 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 Pfam PF01546 Peptidase family M20/M25/M40 64 343 1.0E-25 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 Gene3D G3DSA:3.30.70.360 155 264 6.1E-61 T 23-10-2018 A3L14_07725 3238e88a4b7a66282396b92bb7fa3414 351 SUPERFAMILY SSF55031 155 271 3.59E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L14_06455 0b8e898e3531a019338d93a1cc8620f4 279 Gene3D G3DSA:3.40.50.150 88 279 5.6E-59 T 23-10-2018 A3L14_06455 0b8e898e3531a019338d93a1cc8620f4 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 27 277 41.685 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A3L14_06455 0b8e898e3531a019338d93a1cc8620f4 279 SUPERFAMILY SSF53335 20 277 6.55E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06455 0b8e898e3531a019338d93a1cc8620f4 279 Gene3D G3DSA:3.30.300.110 20 87 8.2E-29 T 23-10-2018 A3L14_06455 0b8e898e3531a019338d93a1cc8620f4 279 Pfam PF02475 Met-10+ like-protein 30 224 7.2E-69 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 Pfam PF00270 DEAD/DEAH box helicase 220 381 1.3E-23 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 Pfam PF00271 Helicase conserved C-terminal domain 438 536 2.8E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 Gene3D G3DSA:3.40.50.300 201 402 1.4E-50 T 23-10-2018 A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 Gene3D G3DSA:3.40.50.300 404 590 7.8E-29 T 23-10-2018 A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 SUPERFAMILY SSF52540 228 552 1.03E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 SMART SM00487 213 410 5.7E-29 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_08045 1442aeaa2af2bf7dff89eb6a4a615c81 845 SMART SM00490 453 538 1.0E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_04065 4dd35103eb0a718bfb57691d8f73b418 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.68 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_04065 4dd35103eb0a718bfb57691d8f73b418 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 2.6E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A3L14_04065 4dd35103eb0a718bfb57691d8f73b418 95 Gene3D G3DSA:3.30.1360.10 1 94 4.0E-34 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_04065 4dd35103eb0a718bfb57691d8f73b418 95 SUPERFAMILY SSF55257 1 93 6.54E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_04065 4dd35103eb0a718bfb57691d8f73b418 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L14_03475 202cac4067be428ae272e78e5d39399d 226 Pfam PF00149 Calcineurin-like phosphoesterase 15 112 9.1E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_03475 202cac4067be428ae272e78e5d39399d 226 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 9 220 3.0E-48 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A3L14_03475 202cac4067be428ae272e78e5d39399d 226 SUPERFAMILY SSF56300 17 126 3.8E-15 T 23-10-2018 A3L14_03475 202cac4067be428ae272e78e5d39399d 226 PIRSF PIRSF000887 3 224 4.8E-60 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L14_03475 202cac4067be428ae272e78e5d39399d 226 Gene3D G3DSA:3.60.21.10 15 159 4.6E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_06640 4f54a9f0d950a517b977f6ec67566153 954 Gene3D G3DSA:3.40.50.12610 497 711 1.8E-88 T 23-10-2018 A3L14_06640 4f54a9f0d950a517b977f6ec67566153 954 Gene3D G3DSA:2.60.40.3020 713 953 2.7E-110 T 23-10-2018 A3L14_06640 4f54a9f0d950a517b977f6ec67566153 954 Gene3D G3DSA:2.60.40.3030 813 945 2.7E-110 T 23-10-2018 A3L14_06640 4f54a9f0d950a517b977f6ec67566153 954 Gene3D G3DSA:2.40.128.390 603 670 1.8E-88 T 23-10-2018 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 68 1.4E-5 T 23-10-2018 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 176 223 2.2E-4 T 23-10-2018 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 SUPERFAMILY SSF56784 1 223 2.75E-35 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 Hamap MF_00617 Mannosyl-3-phosphoglycerate phosphatase [mngB]. 1 243 36.858 T 23-10-2018 IPR012815 Mannosyl-3-phosphoglycerate phosphatase GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 3 226 2.9E-66 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 Gene3D G3DSA:3.40.50.1000 3 216 1.9E-65 T 23-10-2018 IPR023214 HAD superfamily A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 221 1.9E-15 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 3 222 5.6E-77 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 A3L14_03250 8178052a6517a5ec09d906a09041e3d7 243 Gene3D G3DSA:3.30.980.20 94 176 1.9E-65 T 23-10-2018 A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 3 246 3.7E-68 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 SUPERFAMILY SSF53639 254 429 3.41E-55 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 Gene3D G3DSA:3.40.225.10 255 430 3.2E-64 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 Pfam PF10120 Thiamine-phosphate synthase 262 426 3.3E-55 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 Pfam PF08543 Phosphomethylpyrimidine kinase 10 245 1.9E-71 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 SUPERFAMILY SSF53613 3 241 2.18E-57 T 23-10-2018 IPR029056 Ribokinase-like A3L14_05485 dd8b84807675a86afb2207244bba4c1d 430 Gene3D G3DSA:3.40.1190.20 1 254 1.0E-72 T 23-10-2018 IPR029056 Ribokinase-like A3L14_11480 61dbdeeabe805f9ad0d393a081b385e9 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 5.6E-60 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L14_11480 61dbdeeabe805f9ad0d393a081b385e9 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 41.023 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A3L14_11480 61dbdeeabe805f9ad0d393a081b385e9 184 Pfam PF01725 Ham1 family 3 178 2.4E-49 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L14_11480 61dbdeeabe805f9ad0d393a081b385e9 184 SUPERFAMILY SSF52972 1 182 3.14E-62 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L14_11480 61dbdeeabe805f9ad0d393a081b385e9 184 Gene3D G3DSA:3.90.950.10 1 184 1.8E-70 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L14_06225 f261555e7287ea4c5b7289b0d4a113fb 380 SUPERFAMILY SSF51556 49 342 7.94E-30 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_06225 f261555e7287ea4c5b7289b0d4a113fb 380 Gene3D G3DSA:3.20.20.140 50 338 3.6E-74 T 23-10-2018 A3L14_06225 f261555e7287ea4c5b7289b0d4a113fb 380 Pfam PF01979 Amidohydrolase family 244 371 1.6E-12 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L14_06225 f261555e7287ea4c5b7289b0d4a113fb 380 SUPERFAMILY SSF51338 16 376 8.64E-6 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_06225 f261555e7287ea4c5b7289b0d4a113fb 380 Gene3D G3DSA:2.30.40.10 27 372 3.6E-74 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 379 2.1E-198 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 8.0E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Gene3D G3DSA:3.40.50.300 129 309 9.6E-71 T 23-10-2018 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 66 122 3.8E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.213 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 SUPERFAMILY SSF52540 134 385 7.95E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Gene3D G3DSA:2.40.50.140 24 128 4.0E-25 T 23-10-2018 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 Gene3D G3DSA:1.10.8.60 310 381 2.9E-30 T 23-10-2018 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_10000 f82bbb6a506d941047c9390cd93f642e 398 SMART SM00382 172 311 3.8E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Gene3D G3DSA:2.40.30.10 320 425 9.5E-42 T 23-10-2018 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 SUPERFAMILY SSF52540 3 236 3.91E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 2.2E-37 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 4.7E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.246 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 6.4E-213 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 SUPERFAMILY SSF50465 321 424 1.01E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 2.6E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Gene3D G3DSA:3.40.50.300 1 212 7.7E-87 T 23-10-2018 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Gene3D G3DSA:2.40.30.10 216 310 1.7E-41 T 23-10-2018 A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 SUPERFAMILY SSF50447 213 315 1.56E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_06480 bc60923bf4e3d7b48e0e6f86d0843b33 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.0E-58 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_11195 a0a7f71677fe140bbbb8f5bb7fc216e6 224 SUPERFAMILY SSF109755 25 221 6.07E-17 T 23-10-2018 A3L14_11195 a0a7f71677fe140bbbb8f5bb7fc216e6 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 6.3E-36 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L14_11195 a0a7f71677fe140bbbb8f5bb7fc216e6 224 Gene3D G3DSA:1.20.58.220 1 224 1.2E-48 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_11195 a0a7f71677fe140bbbb8f5bb7fc216e6 224 Pfam PF01865 Protein of unknown function DUF47 6 222 4.5E-44 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L14_06740 36eadef899d43b84b90cca914ba4a8fe 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 3.1E-38 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A3L14_06740 36eadef899d43b84b90cca914ba4a8fe 126 SUPERFAMILY SSF54913 8 104 4.77E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L14_06740 36eadef899d43b84b90cca914ba4a8fe 126 Gene3D G3DSA:3.30.70.120 1 126 4.4E-56 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 SUPERFAMILY SSF53092 6 141 3.66E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 Pfam PF00557 Metallopeptidase family M24 150 350 2.5E-29 T 23-10-2018 IPR000994 Peptidase M24 A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 Gene3D G3DSA:3.40.350.10 8 141 4.2E-19 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 9.4E-12 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 Gene3D G3DSA:3.90.230.10 142 358 9.4E-41 T 23-10-2018 A3L14_04795 8bfa21da46c55a16c3bc7dc3b2b3c96c 358 SUPERFAMILY SSF55920 141 358 4.97E-43 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 3.2E-120 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 Gene3D G3DSA:3.30.230.70 5 243 9.5E-78 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.223 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 1.8E-35 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 SUPERFAMILY SSF54211 10 180 2.43E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 1.9E-15 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02195 c4e6425d9a403a24274c637d24641b2e 249 SUPERFAMILY SSF55666 154 240 1.83E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 5.3E-83 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 Gene3D G3DSA:3.20.20.390 5 252 1.4E-98 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 242 1.6E-78 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 247 35.195 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 SUPERFAMILY SSF51395 19 239 5.49E-46 T 23-10-2018 A3L14_08455 ec254815ef71eee90307487a4fed83f8 253 Pfam PF01884 PcrB family 16 238 3.6E-66 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 7.3E-6 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 7.3E-6 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.035 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 SUPERFAMILY SSF52317 1 187 1.02E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 Gene3D G3DSA:3.40.50.880 1 187 2.7E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 8.7E-10 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 8.7E-10 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 8.7E-10 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 3.4E-81 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.2E-11 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.2E-11 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.2E-11 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.2E-11 T 23-10-2018 A3L14_01450 76d6281a11f30687cd9617cbe487d7ba 189 Pfam PF00117 Glutamine amidotransferase class-I 4 181 7.7E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L14_05210 57c492e960e277d7cd21b34e640fb87b 389 SUPERFAMILY SSF53383 2 385 1.84E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_05210 57c492e960e277d7cd21b34e640fb87b 389 Pfam PF00155 Aminotransferase class I and II 28 378 1.3E-77 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_05210 57c492e960e277d7cd21b34e640fb87b 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L14_05210 57c492e960e277d7cd21b34e640fb87b 389 Gene3D G3DSA:3.90.1150.10 29 378 1.3E-153 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_05210 57c492e960e277d7cd21b34e640fb87b 389 Gene3D G3DSA:3.40.640.10 58 280 1.3E-153 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_02620 5774402e107cd2977c0a880c2a4522db 83 Pfam PF01929 Ribosomal protein L14 44 81 1.4E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02620 5774402e107cd2977c0a880c2a4522db 83 SUPERFAMILY SSF50104 2 80 4.51E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_02620 5774402e107cd2977c0a880c2a4522db 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.746 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A3L14_02620 5774402e107cd2977c0a880c2a4522db 83 Gene3D G3DSA:2.30.30.30 2 83 1.1E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_04165 393512eec42fccc5b77c1356d39f5a00 160 Pfam PF09638 Ph1570 protein 1 156 2.9E-76 T 23-10-2018 IPR023110 PH1570-like domain A3L14_04165 393512eec42fccc5b77c1356d39f5a00 160 SUPERFAMILY SSF159902 1 156 6.41E-69 T 23-10-2018 A3L14_04165 393512eec42fccc5b77c1356d39f5a00 160 Gene3D G3DSA:3.40.1600.10 1 157 2.7E-71 T 23-10-2018 IPR036807 PH1570-like superfamily A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 Pfam PF13416 Bacterial extracellular solute-binding protein 95 390 3.0E-51 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 SUPERFAMILY SSF53850 74 445 7.41E-90 T 23-10-2018 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 182 199 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 Gene3D G3DSA:3.40.190.10 80 406 3.0E-136 T 23-10-2018 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 Gene3D G3DSA:3.40.190.10 187 421 3.0E-136 T 23-10-2018 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 PRINTS PR00181 Maltose binding protein signature 179 198 9.4E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 PRINTS PR00181 Maltose binding protein signature 277 296 9.4E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 PRINTS PR00181 Maltose binding protein signature 406 425 9.4E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 PRINTS PR00181 Maltose binding protein signature 200 219 9.4E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L14_00950 f912b1cb2fa05ea95be8fd28413de815 451 PRINTS PR00181 Maltose binding protein signature 117 135 9.4E-10 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 338 9.8E-87 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 5.2E-41 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Pfam PF01472 PUA domain 506 577 1.1E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Gene3D G3DSA:3.10.450.90 427 501 5.5E-28 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 SMART SM00359 505 579 3.7E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 SUPERFAMILY SSF88697 504 578 7.18E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Gene3D G3DSA:3.20.20.105 1 356 1.3E-122 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 1.1E-23 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Gene3D G3DSA:3.90.1020.10 357 426 1.3E-27 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Gene3D G3DSA:2.30.130.10 502 579 9.2E-34 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 SUPERFAMILY SSF51713 4 355 1.57E-116 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 388 2.7E-167 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 484 576 1.3E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 2.6E-40 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 SUPERFAMILY SSF88802 357 502 3.92E-42 T 23-10-2018 A3L14_05580 9a0bdcd6dc0b67f3ffb756138c8d2c14 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.269 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L14_06035 d75ccddd962dbd96d4252f3e208a0eae 332 SUPERFAMILY SSF53383 15 317 4.45E-55 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_06035 d75ccddd962dbd96d4252f3e208a0eae 332 Pfam PF00155 Aminotransferase class I and II 31 315 4.8E-32 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_06035 d75ccddd962dbd96d4252f3e208a0eae 332 Gene3D G3DSA:3.90.1150.10 19 315 5.7E-71 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_06035 d75ccddd962dbd96d4252f3e208a0eae 332 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L14_06035 d75ccddd962dbd96d4252f3e208a0eae 332 Gene3D G3DSA:3.40.640.10 31 233 5.7E-71 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_01830 14fb0d7e99b913569cee4ddec3bb714f 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01830 14fb0d7e99b913569cee4ddec3bb714f 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.917 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L14_01830 14fb0d7e99b913569cee4ddec3bb714f 125 Pfam PF01092 Ribosomal protein S6e 4 124 1.1E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01830 14fb0d7e99b913569cee4ddec3bb714f 125 SMART SM01405 4 124 6.7E-52 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02030 a3a25563e4d84d6a06c241b42a18c45f 344 Gene3D G3DSA:3.40.50.10620 101 237 3.1E-66 T 23-10-2018 A3L14_02030 a3a25563e4d84d6a06c241b42a18c45f 344 Pfam PF11536 Protein of unknown function (DUF3226) 103 337 3.7E-79 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L14_02030 a3a25563e4d84d6a06c241b42a18c45f 344 ProDom PD038575 MJECL12 PLASMID PH0156 102 324 1.0E-83 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L14_02030 a3a25563e4d84d6a06c241b42a18c45f 344 SUPERFAMILY SSF160945 101 337 5.62E-84 T 23-10-2018 A3L14_02030 a3a25563e4d84d6a06c241b42a18c45f 344 Gene3D G3DSA:1.10.3490.10 238 324 3.1E-66 T 23-10-2018 A3L14_02835 e2d6fd73e35c002414c6ed298c43e037 351 SUPERFAMILY SSF53686 2 349 2.75E-71 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_02835 e2d6fd73e35c002414c6ed298c43e037 351 Gene3D G3DSA:3.40.50.1100 91 186 7.8E-82 T 23-10-2018 A3L14_02835 e2d6fd73e35c002414c6ed298c43e037 351 Gene3D G3DSA:3.40.50.1100 60 349 7.8E-82 T 23-10-2018 A3L14_02835 e2d6fd73e35c002414c6ed298c43e037 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 78 345 9.6E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 Pfam PF00572 Ribosomal protein L13 3 103 2.2E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 SUPERFAMILY SSF52161 2 142 3.4E-43 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 2.5E-63 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.347 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 Gene3D G3DSA:3.90.1180.10 1 142 1.1E-56 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02685 ff502e733545c71f6be85e5204784e2b 142 PIRSF PIRSF002181 1 142 1.5E-42 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Pfam PF14890 Intein splicing domain 158 754 4.5E-17 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF51294 147 754 7.46E-32 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF52540 12 147 4.07E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF48019 843 932 4.08E-23 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 49 149 1.3E-13 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF46785 311 381 1.65E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SMART SM00305 715 760 2.1E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SMART SM00306 145 244 1.0E-14 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF55608 528 636 6.8E-11 T 23-10-2018 IPR027434 Homing endonuclease A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:1.20.272.10 842 934 2.9E-36 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Pfam PF08542 Replication factor C C-terminal domain 843 928 3.9E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 584 599 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 749 758 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 435 447 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 544 556 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 731 748 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 PRINTS PR00379 Intein signature 211 224 1.4E-16 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Pfam PF14528 LAGLIDADG-like domain 543 631 5.6E-9 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:2.170.16.10 152 296 1.2E-13 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 147 224 7.5E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SMART SM00382 45 177 1.1E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:2.170.16.10 666 761 5.7E-9 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 733 755 9.4E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 SUPERFAMILY SSF52540 755 825 3.88E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:1.10.8.60 778 841 6.2E-25 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:3.40.50.300 6 151 1.1E-40 T 23-10-2018 A3L14_10170 ef7e8943c971eaedcddfa0f7836f47fb 934 Gene3D G3DSA:3.10.28.10 434 621 8.4E-20 T 23-10-2018 IPR027434 Homing endonuclease A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Gene3D G3DSA:3.40.50.20 2 94 4.0E-22 T 23-10-2018 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 4.9E-59 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 SMART SM01210 328 418 1.0E-17 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 1.4E-11 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 417 1.2E-146 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 SUPERFAMILY SSF51246 327 417 2.28E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 36.239 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 SUPERFAMILY SSF56059 103 323 8.49E-48 T 23-10-2018 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 1.5E-23 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 SUPERFAMILY SSF52440 1 102 2.88E-25 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 SMART SM01209 102 296 3.7E-94 T 23-10-2018 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Gene3D G3DSA:3.30.1490.20 122 187 1.1E-14 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Gene3D G3DSA:3.90.600.10 329 415 1.1E-7 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01395 11682cedec2ccb337a229f0a2258d0ce 438 Gene3D G3DSA:3.30.470.20 189 328 9.5E-47 T 23-10-2018 A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 Pfam PF03551 Transcriptional regulator PadR-like family 377 440 3.3E-9 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 SMART SM00418 366 444 2.7E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 Gene3D G3DSA:1.10.10.10 371 443 4.8E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 353 1.8E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 SUPERFAMILY SSF53686 4 358 2.1E-73 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 Gene3D G3DSA:3.40.50.1100 49 358 7.6E-97 T 23-10-2018 A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 Gene3D G3DSA:3.40.50.1100 96 192 7.6E-97 T 23-10-2018 A3L14_03045 f44a368f11053211a9f0faed4adb9e9e 444 SUPERFAMILY SSF46785 373 442 4.36E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 Gene3D G3DSA:3.40.50.720 2 239 5.0E-80 T 23-10-2018 A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 SUPERFAMILY SSF51735 5 239 3.94E-78 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 1.1E-57 T 23-10-2018 A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 9.2E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L14_04715 2185d41b904a5e92cc62c96dfe52525e 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 170 0.007 T 23-10-2018 A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 23 366 5.8E-148 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 Pfam PF13353 4Fe-4S single cluster domain 32 116 2.2E-6 T 23-10-2018 A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 SMART SM00729 25 227 0.001 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 SUPERFAMILY SSF102114 25 336 4.97E-51 T 23-10-2018 A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 Pfam PF04055 Radical SAM superfamily 29 191 1.3E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 Pfam PF13186 Iron-sulfur cluster-binding domain 253 331 5.6E-16 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L14_09870 a86418f76a6ec568276bfb2649e878be 376 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 31 42 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08015 d5917787fc5439dbb58d402e0686e54f 263 SMART SM00382 26 211 4.0E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08015 d5917787fc5439dbb58d402e0686e54f 263 Pfam PF00005 ABC transporter 27 162 1.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_08015 d5917787fc5439dbb58d402e0686e54f 263 SUPERFAMILY SSF52540 2 220 9.84E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08015 d5917787fc5439dbb58d402e0686e54f 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_08015 d5917787fc5439dbb58d402e0686e54f 263 Gene3D G3DSA:3.40.50.300 1 252 1.3E-69 T 23-10-2018 A3L14_00145 249d3cd6285c8a71b5ed2d95029eab32 242 Gene3D G3DSA:3.40.50.10900 1 242 4.5E-73 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L14_00145 249d3cd6285c8a71b5ed2d95029eab32 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 8 235 5.7E-68 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A3L14_00145 249d3cd6285c8a71b5ed2d95029eab32 242 SUPERFAMILY SSF159659 11 240 2.88E-49 T 23-10-2018 A3L14_00145 249d3cd6285c8a71b5ed2d95029eab32 242 Pfam PF09754 PAC2 family 19 222 2.9E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 SUPERFAMILY SSF100950 4 311 1.61E-101 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 1.6E-97 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 Gene3D G3DSA:1.20.120.420 1 114 5.0E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 Pfam PF01008 Initiation factor 2 subunit family 19 299 1.5E-93 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 4.8E-146 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A3L14_09605 e9b9dc9d5988f0fba917c27d7433a93a 322 Gene3D G3DSA:3.40.50.10470 115 310 4.7E-84 T 23-10-2018 A3L14_04895 5b6db93df66baea327910b1b3ea944e3 419 Pfam PF04055 Radical SAM superfamily 123 287 8.8E-27 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_04895 5b6db93df66baea327910b1b3ea944e3 419 SMART SM00729 115 333 1.9E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_04895 5b6db93df66baea327910b1b3ea944e3 419 Gene3D G3DSA:3.20.20.70 113 358 4.3E-37 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_04895 5b6db93df66baea327910b1b3ea944e3 419 SUPERFAMILY SSF102114 111 335 1.44E-37 T 23-10-2018 A3L14_08250 de265e48b26840aff5654e62841544a7 235 Gene3D G3DSA:2.40.50.580 1 79 1.6E-25 T 23-10-2018 A3L14_08250 de265e48b26840aff5654e62841544a7 235 Pfam PF03749 Sugar fermentation stimulation protein 15 220 3.5E-48 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L14_08250 de265e48b26840aff5654e62841544a7 235 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 8 233 1.6E-53 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L14_08250 de265e48b26840aff5654e62841544a7 235 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 4 234 38.686 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L14_08250 de265e48b26840aff5654e62841544a7 235 Gene3D G3DSA:3.40.1350.60 80 233 6.6E-40 T 23-10-2018 A3L14_10020 48a32ea49ca49c5127f37f39036efe04 315 Pfam PF04055 Radical SAM superfamily 36 194 1.8E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_10020 48a32ea49ca49c5127f37f39036efe04 315 SMART SM00729 24 238 2.0E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_10020 48a32ea49ca49c5127f37f39036efe04 315 Gene3D G3DSA:3.20.20.70 16 245 7.8E-25 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_10020 48a32ea49ca49c5127f37f39036efe04 315 SUPERFAMILY SSF102114 18 289 6.41E-36 T 23-10-2018 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 SUPERFAMILY SSF52490 2 199 1.44E-39 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.239 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.5E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 Gene3D G3DSA:3.40.50.1440 2 363 1.2E-85 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 SMART SM00864 2 199 3.0E-33 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_01500 192a219199ae577e046e6b37f50484c1 389 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 4 168 1.1E-26 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_08945 e0fb1123f20bd7041e232a6f69da87fd 189 SMART SM01022 4 104 1.8E-23 T 23-10-2018 IPR007374 ASCH domain A3L14_08945 e0fb1123f20bd7041e232a6f69da87fd 189 Pfam PF04266 ASCH domain 4 103 1.1E-15 T 23-10-2018 IPR007374 ASCH domain A3L14_08945 e0fb1123f20bd7041e232a6f69da87fd 189 SUPERFAMILY SSF88697 1 103 8.75E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_05395 55a331321aad171e795f6247b2da48a3 512 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_05395 55a331321aad171e795f6247b2da48a3 512 SUPERFAMILY SSF52540 258 495 9.37E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05395 55a331321aad171e795f6247b2da48a3 512 Pfam PF00005 ABC transporter 23 173 1.7E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_05395 55a331321aad171e795f6247b2da48a3 512 SMART SM00382 32 221 2.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05395 55a331321aad171e795f6247b2da48a3 512 Gene3D G3DSA:3.40.50.300 257 501 1.0E-43 T 23-10-2018 A3L14_05395 55a331321aad171e795f6247b2da48a3 512 Pfam PF00005 ABC transporter 278 434 1.4E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_05395 55a331321aad171e795f6247b2da48a3 512 SUPERFAMILY SSF52540 5 232 9.46E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05395 55a331321aad171e795f6247b2da48a3 512 Gene3D G3DSA:3.40.50.300 1 242 3.5E-57 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 755 6.4E-264 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 SUPERFAMILY SSF54975 1 88 1.24E-26 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Gene3D G3DSA:3.90.870.50 6 362 3.5E-145 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 PIRSF PIRSF006256 1 765 5.6E-285 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Pfam PF00814 Glycoprotease family 610 740 9.2E-6 T 23-10-2018 IPR000905 Gcp-like domain A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Pfam PF07503 HypF finger 158 191 6.0E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Pfam PF07503 HypF finger 108 141 1.5E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Gene3D G3DSA:3.30.110.120 252 371 3.5E-145 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Pfam PF01300 Telomere recombination 209 383 1.1E-46 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Gene3D G3DSA:3.30.420.350 486 743 8.2E-105 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 SUPERFAMILY SSF53067 401 737 1.33E-6 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Pfam PF00708 Acylphosphatase 4 87 9.1E-24 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 Gene3D G3DSA:3.30.420.360 383 755 8.2E-105 T 23-10-2018 A3L14_03165 f76e0d45402a0ed34e0ad768d48a0f18 772 SUPERFAMILY SSF55821 175 390 5.49E-46 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 Gene3D G3DSA:3.30.70.2510 162 275 1.3E-29 T 23-10-2018 A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 9 385 1.5E-143 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 Gene3D G3DSA:3.30.70.3190 276 384 2.1E-28 T 23-10-2018 A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 SUPERFAMILY SSF55120 271 383 2.7E-11 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 51.067 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L14_04280 9cbe58ca697076ec313dca0020c397e6 386 Pfam PF02926 THUMP domain 59 162 2.8E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_05665 e86c04aa30a172b178f4645b5b933476 264 SUPERFAMILY SSF55961 3 131 6.37E-5 T 23-10-2018 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 SUPERFAMILY SSF54211 353 514 7.05E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 SMART SM00387 31 182 2.0E-9 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.494 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Gene3D G3DSA:1.10.8.50 233 310 3.6E-9 T 23-10-2018 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 7.0E-102 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 2.1E-230 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Gene3D G3DSA:3.30.565.10 1 232 1.4E-67 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 PIRSF PIRSF006553 1 563 3.9E-212 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 SUPERFAMILY SSF55874 18 229 4.58E-27 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Gene3D G3DSA:3.30.230.10 353 563 2.4E-71 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 507 7.0E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L14_06560 8552bba6825431c1d00e1fd1b04d75e7 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 146 9.6E-12 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L14_11290 149dedb9fe6100949231acee0623f25d 431 Pfam PF00374 Nickel-dependent hydrogenase 47 114 1.0E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_11290 149dedb9fe6100949231acee0623f25d 431 SUPERFAMILY SSF56762 18 380 1.09E-103 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11290 149dedb9fe6100949231acee0623f25d 431 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 47 72 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L14_11290 149dedb9fe6100949231acee0623f25d 431 Gene3D G3DSA:1.10.645.20 9 380 6.2E-123 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11290 149dedb9fe6100949231acee0623f25d 431 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 380 1.8E-59 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_03195 94851c46167efd0bf1ff125d462757da 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 6.8E-27 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L14_03195 94851c46167efd0bf1ff125d462757da 139 Gene3D G3DSA:2.20.28.10 69 123 5.4E-27 T 23-10-2018 A3L14_03195 94851c46167efd0bf1ff125d462757da 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A3L14_03195 94851c46167efd0bf1ff125d462757da 139 PIRSF PIRSF004761 1 137 5.4E-34 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L14_03195 94851c46167efd0bf1ff125d462757da 139 Gene3D G3DSA:3.30.2320.50 2 130 5.4E-27 T 23-10-2018 A3L14_03195 94851c46167efd0bf1ff125d462757da 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.34 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L14_03775 c657ba1493f2634b4d22f5d157c05b2e 224 Gene3D G3DSA:1.10.10.10 144 222 1.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03775 c657ba1493f2634b4d22f5d157c05b2e 224 SUPERFAMILY SSF46785 150 223 1.7E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_06500 e7c79361c8683067d25fdc4525bd9c39 258 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_06500 e7c79361c8683067d25fdc4525bd9c39 258 Gene3D G3DSA:3.40.50.300 1 234 3.4E-45 T 23-10-2018 A3L14_06500 e7c79361c8683067d25fdc4525bd9c39 258 SUPERFAMILY SSF52540 1 216 2.61E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06500 e7c79361c8683067d25fdc4525bd9c39 258 Pfam PF00005 ABC transporter 17 154 1.4E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06500 e7c79361c8683067d25fdc4525bd9c39 258 SMART SM00382 25 201 4.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04605 bbb2f7df993f2079255affbfc78bc023 116 SUPERFAMILY SSF46579 6 110 1.31E-22 T 23-10-2018 A3L14_04605 bbb2f7df993f2079255affbfc78bc023 116 Gene3D G3DSA:1.10.287.370 1 116 1.0E-39 T 23-10-2018 IPR009053 Prefoldin A3L14_04605 bbb2f7df993f2079255affbfc78bc023 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 49.164 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L14_04605 bbb2f7df993f2079255affbfc78bc023 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 1.8E-39 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L14_04605 bbb2f7df993f2079255affbfc78bc023 116 Pfam PF01920 Prefoldin subunit 9 111 1.2E-23 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 59.335 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 PIRSF PIRSF015883 9 454 3.2E-158 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 Gene3D G3DSA:3.30.1110.20 31 203 7.4E-153 T 23-10-2018 A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 Gene3D G3DSA:3.40.1190.20 24 447 7.4E-153 T 23-10-2018 IPR029056 Ribokinase-like A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 SUPERFAMILY SSF53613 2 452 8.18E-155 T 23-10-2018 IPR029056 Ribokinase-like A3L14_03240 179b201ebd1d7246e9c59cf6b36ea499 454 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 24 447 4.6E-95 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L14_09715 c135839eb59a4f10da7697af7675b217 364 Pfam PF03065 Glycosyl hydrolase family 57 56 313 1.8E-36 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L14_09715 c135839eb59a4f10da7697af7675b217 364 Gene3D G3DSA:3.20.110.20 2 329 1.2E-22 T 23-10-2018 A3L14_09715 c135839eb59a4f10da7697af7675b217 364 SUPERFAMILY SSF88713 2 307 1.17E-34 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 SUPERFAMILY SSF55920 2 295 1.2E-67 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.758 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.6E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 SUPERFAMILY SSF46785 196 271 4.9E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 8.2E-120 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 Gene3D G3DSA:1.10.10.10 196 272 1.8E-106 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 Gene3D G3DSA:3.90.230.10 9 286 1.8E-106 T 23-10-2018 A3L14_03985 333476850c79d7cfbe7c08a591bb3c62 295 Pfam PF00557 Metallopeptidase family M24 7 287 4.2E-45 T 23-10-2018 IPR000994 Peptidase M24 A3L14_05195 83ce7033693600892e1e6706102754f6 180 Pfam PF13238 AAA domain 3 116 1.9E-21 T 23-10-2018 A3L14_05195 83ce7033693600892e1e6706102754f6 180 SUPERFAMILY SSF52540 1 155 9.67E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05195 83ce7033693600892e1e6706102754f6 180 Hamap MF_00039 Putative adenylate kinase. 1 160 25.288 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L14_05195 83ce7033693600892e1e6706102754f6 180 Gene3D G3DSA:3.40.50.300 1 180 5.0E-56 T 23-10-2018 A3L14_08960 e1a9d8f247e4e24c784394690cbadb57 210 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 182 7.3E-55 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A3L14_08960 e1a9d8f247e4e24c784394690cbadb57 210 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 1.3E-31 T 23-10-2018 A3L14_08960 e1a9d8f247e4e24c784394690cbadb57 210 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 171 8.1E-19 T 23-10-2018 A3L14_08960 e1a9d8f247e4e24c784394690cbadb57 210 SUPERFAMILY SSF56784 2 203 2.53E-40 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_08960 e1a9d8f247e4e24c784394690cbadb57 210 Gene3D G3DSA:3.40.50.1000 1 199 2.0E-52 T 23-10-2018 IPR023214 HAD superfamily A3L14_01405 95569628772dc65a4107525b40e15eee 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 1.7E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01405 95569628772dc65a4107525b40e15eee 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 6.0E-22 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01405 95569628772dc65a4107525b40e15eee 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 2.6E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01405 95569628772dc65a4107525b40e15eee 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.153 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01405 95569628772dc65a4107525b40e15eee 80 SUPERFAMILY SSF82697 3 78 6.1E-24 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01405 95569628772dc65a4107525b40e15eee 80 Gene3D G3DSA:3.30.1280.10 1 80 5.3E-28 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 4.0E-88 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 SUPERFAMILY SSF56784 1 225 2.49E-50 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 Gene3D G3DSA:1.10.150.520 16 94 1.7E-87 T 23-10-2018 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 91 195 1.8E-13 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 Gene3D G3DSA:3.40.50.1000 3 219 1.7E-87 T 23-10-2018 IPR023214 HAD superfamily A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 1.3E-33 T 23-10-2018 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 188 2.0E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06830 03554aa7b8b68c27c13940ce20e8984b 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 94 193 8.4E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_07545 a7c2d24400e7b9c6c58c2ab9f8a81999 91 Gene3D G3DSA:2.10.260.10 4 44 4.7E-10 T 23-10-2018 A3L14_07545 a7c2d24400e7b9c6c58c2ab9f8a81999 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 49 1.2E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_07545 a7c2d24400e7b9c6c58c2ab9f8a81999 91 SUPERFAMILY SSF89447 4 46 1.44E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_07545 a7c2d24400e7b9c6c58c2ab9f8a81999 91 SMART SM00966 6 51 1.8E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_07545 a7c2d24400e7b9c6c58c2ab9f8a81999 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 2.1E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_00045 2e3a2c44d7fa746b0c615c7b4ced21bc 278 Pfam PF01513 ATP-NAD kinase 2 261 1.0E-71 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L14_00045 2e3a2c44d7fa746b0c615c7b4ced21bc 278 SUPERFAMILY SSF111331 2 266 4.71E-73 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L14_00045 2e3a2c44d7fa746b0c615c7b4ced21bc 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 30.128 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L14_00045 2e3a2c44d7fa746b0c615c7b4ced21bc 278 Gene3D G3DSA:3.40.50.10330 20 267 7.5E-71 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L14_00045 2e3a2c44d7fa746b0c615c7b4ced21bc 278 Gene3D G3DSA:2.60.200.30 121 254 7.5E-71 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 31.8 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 Gene3D G3DSA:2.30.30.30 2 121 1.9E-52 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 SUPERFAMILY SSF50104 6 116 2.11E-38 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 6.0E-35 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 Pfam PF00467 KOW motif 48 79 1.0E-10 T 23-10-2018 IPR005824 KOW A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 2.3E-57 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02535 fdef1170e846a2e7bd35e8004c4cfb64 121 SMART SM00739 45 72 7.3E-8 T 23-10-2018 IPR005824 KOW A3L14_06290 325ec105ec186637750c998b25ef397a 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 6.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 6.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 6.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 6.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 6.4E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 6.9E-93 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_06290 325ec105ec186637750c998b25ef397a 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 14 97 3.1E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_06290 325ec105ec186637750c998b25ef397a 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 5.2E-53 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L14_06290 325ec105ec186637750c998b25ef397a 311 Gene3D G3DSA:3.40.50.150 101 310 3.6E-72 T 23-10-2018 A3L14_06290 325ec105ec186637750c998b25ef397a 311 SUPERFAMILY SSF53335 20 306 5.23E-62 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06290 325ec105ec186637750c998b25ef397a 311 Gene3D G3DSA:3.30.70.3130 5 96 5.0E-18 T 23-10-2018 A3L14_05130 cd2b79a0b9eee09f907c376af3e9ca0c 405 SUPERFAMILY SSF52317 51 315 1.37E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_11205 1b26b864702c2c76c433e7468a182be0 552 Pfam PF00149 Calcineurin-like phosphoesterase 323 498 1.4E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_11205 1b26b864702c2c76c433e7468a182be0 552 SUPERFAMILY SSF56300 327 525 2.06E-32 T 23-10-2018 A3L14_11205 1b26b864702c2c76c433e7468a182be0 552 Gene3D G3DSA:3.60.21.10 325 546 2.7E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 218 244 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 270 294 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 295 313 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 188 202 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 314 330 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 63 79 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 PRINTS PR01050 Pyruvate kinase family signature 245 269 2.6E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 Pfam PF02887 Pyruvate kinase, alpha/beta domain 367 474 1.9E-24 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 Pfam PF00224 Pyruvate kinase, barrel domain 6 339 4.6E-120 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 SUPERFAMILY SSF50800 75 167 4.88E-24 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A3L14_06680 2933f9875cbb397c956323a1707422db 477 Gene3D G3DSA:3.20.20.60 7 336 4.0E-169 T 23-10-2018 A3L14_06680 2933f9875cbb397c956323a1707422db 477 SUPERFAMILY SSF51621 4 339 3.49E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L14_06680 2933f9875cbb397c956323a1707422db 477 Gene3D G3DSA:3.40.1380.20 337 473 4.0E-169 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 477 2.0E-170 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 SUPERFAMILY SSF52935 324 477 1.28E-32 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_06680 2933f9875cbb397c956323a1707422db 477 Gene3D G3DSA:2.40.33.10 74 170 4.0E-169 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L14_04930 ced494223fcda6d376b6014ebea21b2d 189 Pfam PF01944 Stage II sporulation protein M 17 184 2.0E-34 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L14_11315 653c51493ecec342dac86ac0eba60fbd 116 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 9 112 7.1E-33 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_11315 653c51493ecec342dac86ac0eba60fbd 116 Pfam PF03334 Na+/H+ antiporter subunit 9 97 1.9E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_09660 71ce6734f8117f5a80578243706f1ae4 166 Gene3D G3DSA:3.40.50.880 1 166 3.3E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_09660 71ce6734f8117f5a80578243706f1ae4 166 Pfam PF01965 DJ-1/PfpI family 1 163 6.3E-58 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A3L14_09660 71ce6734f8117f5a80578243706f1ae4 166 SUPERFAMILY SSF52317 1 166 1.15E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_09660 71ce6734f8117f5a80578243706f1ae4 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 166 1.6E-66 T 23-10-2018 IPR006286 Deglycase PfpI A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 SUPERFAMILY SSF54999 3 100 4.84E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 2.3E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 Gene3D G3DSA:3.30.70.600 1 101 8.7E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 3.5E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 SMART SM01403 5 99 1.7E-40 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.613 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.4E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L14_06475 e8ea0b6098998b9a5a925e014c242187 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_06745 277faf270947841e02fda1667eecb476 404 Gene3D G3DSA:3.40.50.1950 15 186 5.8E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L14_06745 277faf270947841e02fda1667eecb476 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 375 8.3E-57 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L14_06745 277faf270947841e02fda1667eecb476 404 Pfam PF02441 Flavoprotein 19 188 1.4E-41 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L14_06745 277faf270947841e02fda1667eecb476 404 Gene3D G3DSA:3.40.50.10300 187 404 2.1E-70 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L14_06745 277faf270947841e02fda1667eecb476 404 SUPERFAMILY SSF52507 18 217 1.18E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L14_06745 277faf270947841e02fda1667eecb476 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 1.1E-126 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A3L14_06745 277faf270947841e02fda1667eecb476 404 SUPERFAMILY SSF102645 181 402 9.16E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 SMART SM00382 29 225 1.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 Pfam PF00005 ABC transporter 21 178 6.7E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 Gene3D G3DSA:3.40.50.300 2 251 1.3E-71 T 23-10-2018 A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 SUPERFAMILY SSF52540 4 240 6.29E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04630 0a3856a60f5cb0b8a3e78be97bda124d 253 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 253 2.6E-106 T 23-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 SUPERFAMILY SSF55729 230 346 4.36E-8 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 Gene3D G3DSA:3.40.50.300 416 630 4.1E-40 T 23-10-2018 A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 Pfam PF00005 ABC transporter 437 573 1.4E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 SMART SM00382 446 625 1.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 Gene3D G3DSA:3.40.630.30 231 349 7.0E-8 T 23-10-2018 A3L14_05480 a15319e8e3d8d12b6888c31720007bc0 631 SUPERFAMILY SSF52540 426 624 1.46E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01215 249904b9c07f3492bb9378ea852ee894 317 Gene3D G3DSA:3.90.25.10 233 317 1.4E-26 T 23-10-2018 A3L14_01215 249904b9c07f3492bb9378ea852ee894 317 SUPERFAMILY SSF51735 1 316 1.22E-86 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_01215 249904b9c07f3492bb9378ea852ee894 317 Gene3D G3DSA:3.40.50.720 1 179 6.6E-52 T 23-10-2018 A3L14_01215 249904b9c07f3492bb9378ea852ee894 317 Gene3D G3DSA:3.90.25.10 180 232 2.6E-14 T 23-10-2018 A3L14_01215 249904b9c07f3492bb9378ea852ee894 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 5.3E-57 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L14_09325 16709d49217923354d69f0e665e4a61c 99 Pfam PF09946 Predicted membrane protein (DUF2178) 6 82 1.1E-6 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L14_08715 b09ee89294ab7bcfb66e799604d5e348 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 3.4E-241 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L14_08715 b09ee89294ab7bcfb66e799604d5e348 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 4.4E-290 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L14_08715 b09ee89294ab7bcfb66e799604d5e348 562 Gene3D G3DSA:3.20.20.240 1 562 1.9E-269 T 23-10-2018 A3L14_08715 b09ee89294ab7bcfb66e799604d5e348 562 SUPERFAMILY SSF51703 9 556 7.65E-231 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L14_05030 2342ee59ba698441bf4f5dcde5d7d19b 200 SMART SM01397 8 198 1.2E-99 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05030 2342ee59ba698441bf4f5dcde5d7d19b 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05030 2342ee59ba698441bf4f5dcde5d7d19b 200 Pfam PF01015 Ribosomal S3Ae family 11 198 1.2E-65 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05030 2342ee59ba698441bf4f5dcde5d7d19b 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.598 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A3L14_06220 923b13c67a9c54858e4177216b30cdcd 132 Gene3D G3DSA:1.20.120.580 1 132 2.6E-10 T 23-10-2018 IPR037038 Bsu32300-like superfamily A3L14_06220 923b13c67a9c54858e4177216b30cdcd 132 SUPERFAMILY SSF81593 6 126 1.02E-5 T 23-10-2018 A3L14_06220 923b13c67a9c54858e4177216b30cdcd 132 Pfam PF01934 Protein of unknown function DUF86 4 119 2.4E-19 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A3L14_04985 12217a84408c1f79775cccdc8b85d880 130 Gene3D G3DSA:3.50.30.10 1 130 2.4E-49 T 23-10-2018 A3L14_04985 12217a84408c1f79775cccdc8b85d880 130 SUPERFAMILY SSF52016 1 128 2.59E-45 T 23-10-2018 A3L14_04985 12217a84408c1f79775cccdc8b85d880 130 Hamap MF_00078 UPF0107 protein . 2 129 33.52 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A3L14_04985 12217a84408c1f79775cccdc8b85d880 130 Pfam PF01989 Protein of unknown function DUF126 24 103 3.0E-36 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A3L14_04985 12217a84408c1f79775cccdc8b85d880 130 PIRSF PIRSF004966 1 130 1.6E-53 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A3L14_04235 6f329d6ca001452043822a3a015c56ef 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 4.1E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_04235 6f329d6ca001452043822a3a015c56ef 247 SUPERFAMILY SSF52540 3 244 3.33E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04235 6f329d6ca001452043822a3a015c56ef 247 Gene3D G3DSA:3.40.50.300 2 241 6.1E-45 T 23-10-2018 A3L14_06835 a3a7ceff9bff38500cc7b98be5c1cd42 136 PIRSF PIRSF014543 1 122 2.0E-44 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L14_06835 a3a7ceff9bff38500cc7b98be5c1cd42 136 Pfam PF12646 Domain of unknown function (DUF3783) 58 113 1.7E-16 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 Pfam PF02347 Glycine cleavage system P-protein 5 442 1.1E-122 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 48.028 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 Gene3D G3DSA:3.40.640.10 81 349 2.6E-152 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 SUPERFAMILY SSF53383 3 445 4.83E-102 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 PIRSF PIRSF006815 3 446 9.0E-161 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L14_03455 5dbdd0be3c0d1f136f33c88f43b70cfe 446 Gene3D G3DSA:3.90.1150.10 70 442 2.6E-152 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 287 491 1.8E-18 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 SUPERFAMILY SSF55681 206 488 7.85E-56 T 23-10-2018 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 SUPERFAMILY SSF52954 503 605 2.87E-31 T 23-10-2018 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 293 321 2.1E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 327 350 2.1E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 483 2.1E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 427 455 2.1E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 517 2.1E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 5.1E-55 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Gene3D G3DSA:3.50.80.10 1 139 2.1E-56 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Gene3D G3DSA:3.30.930.10 202 493 6.1E-62 T 23-10-2018 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Gene3D G3DSA:3.40.50.800 503 606 6.5E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 601 29.038 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 Pfam PF03129 Anticodon binding domain 512 601 3.2E-24 T 23-10-2018 IPR004154 Anticodon-binding A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 25 602 1.7E-173 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L14_04050 db790cbb102da5166dadfd89c158b4c5 625 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 1.0E-66 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L14_00450 151a8822312b2d72eaabaa6ec464fd90 375 Gene3D G3DSA:3.40.50.2000 61 174 2.7E-17 T 23-10-2018 A3L14_00450 151a8822312b2d72eaabaa6ec464fd90 375 Pfam PF00534 Glycosyl transferases group 1 196 351 3.7E-8 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L14_00450 151a8822312b2d72eaabaa6ec464fd90 375 SUPERFAMILY SSF53756 66 374 1.1E-20 T 23-10-2018 A3L14_00450 151a8822312b2d72eaabaa6ec464fd90 375 Gene3D G3DSA:3.40.50.2000 175 357 2.7E-17 T 23-10-2018 A3L14_01005 72327645597abeabe9cf205270c7c699 622 Gene3D G3DSA:1.10.569.10 251 445 3.0E-74 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L14_01005 72327645597abeabe9cf205270c7c699 622 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 217 1.9E-61 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_01005 72327645597abeabe9cf205270c7c699 622 SUPERFAMILY SSF48310 224 608 1.12E-85 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_01005 72327645597abeabe9cf205270c7c699 622 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 243 606 3.2E-77 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_01005 72327645597abeabe9cf205270c7c699 622 SUPERFAMILY SSF56228 1 221 1.1E-56 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_01005 72327645597abeabe9cf205270c7c699 622 Gene3D G3DSA:3.60.9.10 1 222 4.4E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_01005 72327645597abeabe9cf205270c7c699 622 Gene3D G3DSA:1.10.599.10 250 606 3.0E-74 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L14_01005 72327645597abeabe9cf205270c7c699 622 SMART SM00790 4 219 1.9E-92 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_06625 8475140b087874bfb51a227a43380e84 383 Gene3D G3DSA:3.40.50.150 41 236 8.3E-27 T 23-10-2018 A3L14_06625 8475140b087874bfb51a227a43380e84 383 SUPERFAMILY SSF53335 54 161 8.51E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06625 8475140b087874bfb51a227a43380e84 383 Pfam PF13847 Methyltransferase domain 86 157 9.9E-8 T 23-10-2018 IPR025714 Methyltransferase domain A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 1.9E-41 T 23-10-2018 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:3.90.1100.10 21 177 2.2E-12 T 23-10-2018 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 1.7E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:3.90.1110.10 178 336 1.9E-58 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 2.4E-40 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:2.40.50.150 683 874 5.8E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:3.90.1100.10 337 512 1.1E-55 T 23-10-2018 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 1.1E-19 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 1.1E-8 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Gene3D G3DSA:2.40.270.10 653 1011 5.8E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 4.0E-132 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04563 RNA polymerase beta subunit 28 381 4.7E-54 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 SUPERFAMILY SSF64484 12 1116 0.0 T 23-10-2018 A3L14_03420 455b2db412f0718890256b22a61f704e 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1116 3.0E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 3.7E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 SUPERFAMILY SSF54292 17 98 3.23E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 4.8E-22 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 4.8E-22 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 4.8E-22 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 4.8E-22 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 4.8E-22 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 Gene3D G3DSA:3.10.20.440 5 99 2.5E-32 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 SUPERFAMILY SSF51905 107 433 8.42E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 6.3E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 6.3E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 6.3E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 6.3E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 6.3E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 8.2E-27 T 23-10-2018 A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 Gene3D G3DSA:3.50.50.60 237 367 5.7E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09840 870ec7feca57c37871bb77ffd7bbb9b8 481 Gene3D G3DSA:3.50.50.60 118 441 5.7E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10415 311d8b87d949151e2e3684dd61df7a21 192 Pfam PF09851 Short C-terminal domain 162 189 2.9E-11 T 23-10-2018 IPR018649 SHOCT domain A3L14_10415 311d8b87d949151e2e3684dd61df7a21 192 Pfam PF14470 Bacterial PH domain 13 105 1.4E-20 T 23-10-2018 IPR039519 YokE-like, PH domain A3L14_09935 eebd841f2f845985f8ed352641b77867 282 SUPERFAMILY SSF63380 3 91 6.28E-12 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L14_09935 eebd841f2f845985f8ed352641b77867 282 Gene3D G3DSA:2.40.30.10 2 91 6.0E-11 T 23-10-2018 A3L14_09935 eebd841f2f845985f8ed352641b77867 282 SUPERFAMILY SSF52343 115 249 5.47E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_09935 eebd841f2f845985f8ed352641b77867 282 PIRSF PIRSF006816 1 256 1.6E-40 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L14_09935 eebd841f2f845985f8ed352641b77867 282 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 9.0E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L14_09935 eebd841f2f845985f8ed352641b77867 282 Gene3D G3DSA:3.40.50.80 99 204 4.2E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 SUPERFAMILY SSF52922 286 393 4.71E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 3.6E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 SUPERFAMILY SSF52518 23 278 1.23E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 Gene3D G3DSA:3.40.50.920 283 395 1.3E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 4.1E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_05355 50378319b2fe1efa6c1316ee53e05cd5 396 Gene3D G3DSA:3.40.50.970 11 211 1.2E-77 T 23-10-2018 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 SMART SM00316 68 148 8.1E-9 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 SUPERFAMILY SSF110324 11 63 5.44E-12 T 23-10-2018 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Pfam PF10447 Exosome component EXOSC1/CSL4 66 122 6.4E-5 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Gene3D G3DSA:2.40.50.100 11 61 6.9E-16 T 23-10-2018 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 SUPERFAMILY SSF50249 64 185 1.8E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 192 28.377 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Gene3D G3DSA:2.40.50.140 66 154 3.8E-23 T 23-10-2018 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Gene3D G3DSA:2.20.70.10 155 188 1.4E-16 T 23-10-2018 A3L14_04055 b4e06ad94e71ef791fabab0f4a1103d4 195 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 3.0E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 SUPERFAMILY SSF50249 2 93 1.41E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 SMART SM01382 91 223 8.5E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 SUPERFAMILY SSF50104 94 237 3.67E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.355 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 92 222 8.2E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 SMART SM01383 11 85 2.0E-25 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 2.4E-20 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 PIRSF PIRSF002158 1 239 2.5E-72 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Gene3D G3DSA:2.40.50.140 1 81 5.0E-31 T 23-10-2018 A3L14_02490 6cac7668c83bcfa932ae85fe5f718baa 239 Gene3D G3DSA:2.30.30.30 85 162 2.3E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_00965 8a207dc4c3b1a9e5a9b565bcbd3dd57e 449 Pfam PF08323 Starch synthase catalytic domain 2 202 1.7E-37 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A3L14_00965 8a207dc4c3b1a9e5a9b565bcbd3dd57e 449 Gene3D G3DSA:3.40.50.2000 2 437 5.9E-116 T 23-10-2018 A3L14_00965 8a207dc4c3b1a9e5a9b565bcbd3dd57e 449 Pfam PF00534 Glycosyl transferases group 1 253 419 2.7E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L14_00965 8a207dc4c3b1a9e5a9b565bcbd3dd57e 449 SUPERFAMILY SSF53756 1 440 6.28E-89 T 23-10-2018 A3L14_00965 8a207dc4c3b1a9e5a9b565bcbd3dd57e 449 Gene3D G3DSA:3.40.50.2000 220 427 5.9E-116 T 23-10-2018 A3L14_07060 b9984f8e07f56d0ab0dc0876ddc7b765 186 SUPERFAMILY SSF103247 62 185 1.96E-34 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_07060 b9984f8e07f56d0ab0dc0876ddc7b765 186 Gene3D G3DSA:3.30.310.70 58 186 5.1E-41 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_07060 b9984f8e07f56d0ab0dc0876ddc7b765 186 Pfam PF03625 Domain of unknown function DUF302 99 154 2.9E-20 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L14_01550 64e4c719410f0fe5a6a4be91329929a7 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.771 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L14_01550 64e4c719410f0fe5a6a4be91329929a7 178 SUPERFAMILY SSF50324 1 176 2.35E-68 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L14_01550 64e4c719410f0fe5a6a4be91329929a7 178 Gene3D G3DSA:3.90.80.10 1 178 8.9E-76 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L14_01550 64e4c719410f0fe5a6a4be91329929a7 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 1.2E-58 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L14_01550 64e4c719410f0fe5a6a4be91329929a7 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L14_00940 d3fafeedb38962d6b06e8e7df8e0a256 422 Gene3D G3DSA:1.10.3720.10 171 412 8.2E-45 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00940 d3fafeedb38962d6b06e8e7df8e0a256 422 Gene3D G3DSA:1.10.3720.10 2 81 2.4E-7 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00940 d3fafeedb38962d6b06e8e7df8e0a256 422 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 234 411 1.5E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00940 d3fafeedb38962d6b06e8e7df8e0a256 422 SUPERFAMILY SSF161098 8 68 2.75E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00940 d3fafeedb38962d6b06e8e7df8e0a256 422 SUPERFAMILY SSF161098 176 421 1.31E-52 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08125 2d7ce34f0d0acdb547481976848d5709 143 Gene3D G3DSA:2.40.10.360 81 143 3.1E-15 T 23-10-2018 A3L14_08125 2d7ce34f0d0acdb547481976848d5709 143 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 13 70 7.1E-5 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_08125 2d7ce34f0d0acdb547481976848d5709 143 SUPERFAMILY SSF54585 2 73 2.03E-10 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L14_08125 2d7ce34f0d0acdb547481976848d5709 143 Gene3D G3DSA:3.10.330.10 1 77 4.5E-28 T 23-10-2018 A3L14_08125 2d7ce34f0d0acdb547481976848d5709 143 SMART SM01072 12 74 2.8E-5 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.158 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 4.0E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 Gene3D G3DSA:3.30.70.330 1 98 3.1E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 Pfam PF01282 Ribosomal protein S24e 21 97 5.2E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01530 86e1c6e352c5c63f0f55492b40eaeac9 98 SUPERFAMILY SSF54189 1 97 4.32E-32 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 SUPERFAMILY SSF50331 237 355 2.28E-19 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 Gene3D G3DSA:2.40.50.940 223 348 2.5E-20 T 23-10-2018 A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 SMART SM00382 28 212 4.1E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 Gene3D G3DSA:2.40.50.140 284 339 2.5E-20 T 23-10-2018 A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 Pfam PF00005 ABC transporter 20 161 1.0E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 SUPERFAMILY SSF52540 5 243 4.68E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04430 6a7d7662df226fe58191ed979cff6589 357 Gene3D G3DSA:3.40.50.300 4 222 3.3E-65 T 23-10-2018 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 4.9E-14 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 Gene3D G3DSA:3.40.50.150 62 281 7.5E-76 T 23-10-2018 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 280 36.935 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 Gene3D G3DSA:2.30.140.10 6 60 2.2E-24 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 SUPERFAMILY SSF53335 9 280 5.55E-77 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 TIGRFAM TIGR00417 speE: spermidine synthase 10 274 5.3E-85 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L14_09475 3bf041b39f9d49b8bf4f049ea5e72312 283 Pfam PF01564 Spermine/spermidine synthase domain 64 241 1.7E-52 T 23-10-2018 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.588 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 6.7E-36 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Gene3D G3DSA:3.90.600.20 156 251 1.0E-32 T 23-10-2018 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Pfam PF01336 OB-fold nucleic acid binding domain 270 341 4.9E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Gene3D G3DSA:2.40.50.1010 252 401 1.5E-43 T 23-10-2018 A3L14_06160 9da7a68e888e59057088fa77ecfdbaa1 428 Gene3D G3DSA:3.30.70.2200 2 155 3.4E-61 T 23-10-2018 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 Gene3D G3DSA:3.40.50.1100 11 236 1.5E-178 T 23-10-2018 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 PIRSF PIRSF001413 6 430 6.0E-157 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 426 6.5E-220 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 Gene3D G3DSA:3.40.50.1100 10 417 1.5E-178 T 23-10-2018 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 SUPERFAMILY SSF53686 27 423 1.14E-111 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 8.4E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.431 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L14_02965 edd0e3d8b22f4d6f224043caf10d336a 441 PIRSF PIRSF500824 1 433 5.4E-214 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 SMART SM01027 433 557 1.2E-56 T 23-10-2018 IPR022712 Beta-Casp domain A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Gene3D G3DSA:3.40.50.10890 401 588 1.5E-165 T 23-10-2018 A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 SMART SM00849 198 428 4.3E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 205 351 7.6E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Gene3D G3DSA:3.30.300.20 72 142 1.4E-63 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 3.2E-299 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 SUPERFAMILY SSF54814 91 141 1.31E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 SUPERFAMILY SSF56281 183 647 3.61E-133 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 SMART SM00322 102 169 4.2E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Pfam PF17214 KH domain 9 76 3.2E-27 T 23-10-2018 IPR033769 KH domain, archaeal A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Pfam PF10996 Beta-Casp domain 433 556 2.6E-24 T 23-10-2018 IPR022712 Beta-Casp domain A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 4.3E-19 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Gene3D G3DSA:3.60.15.10 191 627 1.5E-165 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_03040 778ab007f0c5f00604307feaa13450e1 648 Gene3D G3DSA:3.30.300.230 17 176 1.4E-63 T 23-10-2018 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 SMART SM00419 14 66 2.1E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 SUPERFAMILY SSF82114 88 209 1.31E-38 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.609 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 7.1E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 7.1E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 SUPERFAMILY SSF46785 4 80 3.22E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 Pfam PF01982 Domain of unknown function DUF120 92 209 1.7E-36 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 Gene3D G3DSA:2.40.30.30 85 212 7.1E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 Pfam PF13545 Crp-like helix-turn-helix domain 7 63 2.6E-8 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L14_05170 6c8aab00d34d93ccb8fd520207a7204f 212 Gene3D G3DSA:1.10.10.10 1 83 9.2E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09130 cb0d876a8c5012c6aa6a9060c3e1e5d5 620 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 8 146 1.2E-10 T 23-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal A3L14_09130 cb0d876a8c5012c6aa6a9060c3e1e5d5 620 Pfam PF06202 Amylo-alpha-1,6-glucosidase 228 569 1.5E-10 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 A3L14_09130 cb0d876a8c5012c6aa6a9060c3e1e5d5 620 Gene3D G3DSA:1.50.10.10 215 576 2.6E-42 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A3L14_09130 cb0d876a8c5012c6aa6a9060c3e1e5d5 620 SUPERFAMILY SSF48208 224 583 8.93E-60 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 361 1.5E-33 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 Gene3D G3DSA:3.40.50.620 1 226 3.3E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 SUPERFAMILY SSF52374 2 363 2.72E-67 T 23-10-2018 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.686 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 352 1.6E-43 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 Gene3D G3DSA:1.10.240.10 227 375 2.9E-55 T 23-10-2018 A3L14_08055 ea53ad1d8005a5519e32699f031d68de 375 PIRSF PIRSF006588 1 375 2.8E-130 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A3L14_10575 0d54365719c5275938387d0cdc151394 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 1.1E-78 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A3L14_10575 0d54365719c5275938387d0cdc151394 185 Gene3D G3DSA:3.40.920.10 1 182 5.2E-71 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_10575 0d54365719c5275938387d0cdc151394 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 2.6E-42 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_10575 0d54365719c5275938387d0cdc151394 185 SUPERFAMILY SSF53323 1 179 9.42E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Gene3D G3DSA:3.20.110.20 222 503 1.2E-23 T 23-10-2018 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1330 1349 9.2E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Pfam PF03065 Glycosyl hydrolase family 57 36 537 8.8E-127 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 SUPERFAMILY SSF49344 792 1025 7.45E-79 T 23-10-2018 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 792 1024 1.7E-77 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1036 1264 1.1E-74 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 SUPERFAMILY SSF88713 32 576 1.07E-66 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 SUPERFAMILY SSF49344 1035 1267 6.28E-78 T 23-10-2018 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Gene3D G3DSA:2.60.40.1190 789 1028 8.3E-67 T 23-10-2018 A3L14_00935 14fd10f1d1af9dcec2f9d4e982d2e4eb 1350 Gene3D G3DSA:2.60.40.1190 1034 1269 4.4E-65 T 23-10-2018 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 553 2.4E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 SUPERFAMILY SSF54862 563 628 7.92E-14 T 23-10-2018 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 610 621 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 SUPERFAMILY SSF52518 375 560 1.31E-38 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Pfam PF00037 4Fe-4S binding domain 604 626 1.9E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 206 2.4E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 625 1.2E-218 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Gene3D G3DSA:3.40.50.970 411 572 1.2E-24 T 23-10-2018 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Gene3D G3DSA:3.30.70.20 573 634 6.1E-11 T 23-10-2018 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 Gene3D G3DSA:3.40.50.970 5 198 1.1E-55 T 23-10-2018 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 PIRSF PIRSF006439 11 632 1.9E-220 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 SUPERFAMILY SSF52922 245 323 2.04E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_02130 c5f1848b9c59e7e8db22d3629d56bd1d 634 SUPERFAMILY SSF52518 20 253 1.18E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_06320 f449d7581e5143a5d5f38ad49bad209b 285 Pfam PF00892 EamA-like transporter family 6 139 5.7E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_06320 f449d7581e5143a5d5f38ad49bad209b 285 Pfam PF00892 EamA-like transporter family 149 270 9.1E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_06320 f449d7581e5143a5d5f38ad49bad209b 285 SUPERFAMILY SSF103481 41 143 1.83E-14 T 23-10-2018 A3L14_06320 f449d7581e5143a5d5f38ad49bad209b 285 SUPERFAMILY SSF103481 184 271 1.44E-6 T 23-10-2018 A3L14_04975 7fe85909bdd0e18afe7cd285356af32f 186 Gene3D G3DSA:1.10.10.10 125 185 2.7E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_02075 c5176e2fd71dfb692292cdd720935424 138 Pfam PF03061 Thioesterase superfamily 40 92 1.1E-6 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A3L14_02075 c5176e2fd71dfb692292cdd720935424 138 SUPERFAMILY SSF54637 13 129 1.5E-24 T 23-10-2018 IPR029069 HotDog domain superfamily A3L14_02075 c5176e2fd71dfb692292cdd720935424 138 Gene3D G3DSA:3.10.129.10 1 138 4.3E-41 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Pfam PF00271 Helicase conserved C-terminal domain 346 460 2.7E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Gene3D G3DSA:1.20.1320.20 212 338 2.9E-100 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SMART SM00487 6 201 8.8E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Pfam PF00270 DEAD/DEAH box helicase 14 151 2.8E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SUPERFAMILY SSF52980 575 703 7.24E-38 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Gene3D G3DSA:1.10.150.20 715 789 4.3E-24 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Pfam PF12826 Helix-hairpin-helix motif 732 782 2.1E-10 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SUPERFAMILY SSF47781 715 784 2.89E-16 T 23-10-2018 IPR010994 RuvA domain 2-like A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Gene3D G3DSA:3.40.50.10130 573 714 8.2E-53 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Gene3D G3DSA:3.40.50.300 1 199 2.0E-72 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SMART SM00891 577 657 8.5E-32 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SMART SM00490 372 461 3.0E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Gene3D G3DSA:3.40.50.300 209 478 2.9E-100 T 23-10-2018 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SMART SM00278 728 747 850.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SMART SM00278 760 779 0.0099 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 SUPERFAMILY SSF52540 52 480 6.47E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08470 293965bba9ac3aef9522f23f8af89c03 791 Pfam PF02732 ERCC4 domain 580 698 4.7E-29 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 SUPERFAMILY SSF50249 181 348 3.51E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 Pfam PF01336 OB-fold nucleic acid binding domain 75 151 2.2E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 Gene3D G3DSA:2.40.50.140 58 159 3.7E-20 T 23-10-2018 A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 Gene3D G3DSA:2.40.50.140 167 319 7.4E-11 T 23-10-2018 A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 Pfam PF08646 Replication factor-A C terminal domain 193 278 7.2E-10 T 23-10-2018 IPR013955 Replication factor A, C-terminal A3L14_01880 e449ea55789d5313413f53f1f05efdce 354 SUPERFAMILY SSF50249 53 176 7.71E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 1.2E-246 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Gene3D G3DSA:3.40.50.10490 250 601 2.0E-137 T 23-10-2018 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Pfam PF01380 SIS domain 288 412 2.7E-33 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Pfam PF01380 SIS domain 457 584 4.3E-24 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Gene3D G3DSA:3.40.50.10490 442 587 2.0E-137 T 23-10-2018 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 SUPERFAMILY SSF56235 2 227 1.72E-72 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.952 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Gene3D G3DSA:3.60.20.10 2 239 3.9E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 Pfam PF13522 Glutamine amidotransferase domain 67 187 5.4E-22 T 23-10-2018 A3L14_06635 c0c7938230a1d52b87e688e6bf39f3b1 602 SUPERFAMILY SSF53697 247 602 1.21E-110 T 23-10-2018 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 Gene3D G3DSA:3.30.230.10 2 179 2.5E-58 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 TIGRFAM TIGR00131 gal_kin: galactokinase 3 348 2.7E-77 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 ProSitePatterns PS00106 Galactokinase signature. 8 19 - T 23-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PIRSF PIRSF000530 1 353 5.0E-101 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00473 Galactokinase signature 234 248 3.1E-20 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00473 Galactokinase signature 87 105 3.1E-20 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00473 Galactokinase signature 8 26 3.1E-20 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00473 Galactokinase signature 67 78 3.1E-20 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 SUPERFAMILY SSF55060 183 348 1.4E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 Pfam PF00288 GHMP kinases N terminal domain 94 156 8.4E-15 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 Pfam PF08544 GHMP kinases C terminal 249 320 2.5E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 SUPERFAMILY SSF54211 2 178 4.4E-51 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 Gene3D G3DSA:3.30.70.890 180 350 2.0E-55 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 Pfam PF10509 Galactokinase galactose-binding signature 4 38 1.0E-15 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00959 Mevalonate kinase family signature 6 30 2.4E-40 T 23-10-2018 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00959 Mevalonate kinase family signature 94 116 2.4E-40 T 23-10-2018 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00959 Mevalonate kinase family signature 137 156 2.4E-40 T 23-10-2018 A3L14_09710 82c933e5ed49ed8a0ee959e789af5cac 353 PRINTS PR00959 Mevalonate kinase family signature 297 314 2.4E-40 T 23-10-2018 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 SUPERFAMILY SSF102114 3 274 1.7E-67 T 23-10-2018 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 1.1E-21 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 Pfam PF13353 4Fe-4S single cluster domain 18 104 3.5E-9 T 23-10-2018 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 Pfam PF04055 Radical SAM superfamily 17 172 4.4E-30 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 307 9.8E-124 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 Gene3D G3DSA:3.20.20.70 1 306 8.6E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 SMART SM00729 12 214 1.6E-14 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_10150 bf47f671bf06355b757a7253b3441c59 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 43.04 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L14_00010 640c6ac59543f08b98e6cfa6021c361b 173 PIRSF PIRSF006707 1 173 6.1E-40 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A3L14_00010 640c6ac59543f08b98e6cfa6021c361b 173 Pfam PF01047 MarR family 38 81 8.7E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L14_00010 640c6ac59543f08b98e6cfa6021c361b 173 Gene3D G3DSA:1.10.10.10 2 86 1.6E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00010 640c6ac59543f08b98e6cfa6021c361b 173 SUPERFAMILY SSF46785 3 135 5.4E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 PIRSF PIRSF005378 1 343 4.6E-111 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 Gene3D G3DSA:3.30.360.20 182 276 1.9E-126 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 6.5E-77 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 Gene3D G3DSA:3.65.10.20 5 321 1.9E-126 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 SUPERFAMILY SSF55205 4 216 7.85E-65 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 39.368 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 324 1.4E-126 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 184 275 3.6E-22 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A3L14_02295 fed4468d6f20c38be072376f8e2a7b85 344 SUPERFAMILY SSF52913 185 276 5.49E-23 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 Gene3D G3DSA:2.40.50.140 1 101 1.3E-29 T 23-10-2018 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 Gene3D G3DSA:3.30.930.10 105 430 6.8E-116 T 23-10-2018 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 96 1.7E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 SUPERFAMILY SSF50249 4 99 3.64E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 5.1E-86 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 5.7E-128 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L14_07935 3f7cb603d9a97c3047052f63bfbd549a 430 SUPERFAMILY SSF55681 111 425 1.1E-87 T 23-10-2018 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Gene3D G3DSA:2.60.40.10 1 103 9.7E-20 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 SUPERFAMILY SSF81296 22 81 7.93E-10 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 19 80 1.5E-6 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Gene3D G3DSA:2.60.40.10 104 196 1.3E-22 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 SUPERFAMILY SSF51011 586 646 2.94E-6 T 23-10-2018 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 SUPERFAMILY SSF81296 106 202 8.26E-12 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 SMART SM00642 209 577 6.1E-88 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Gene3D G3DSA:3.20.20.80 197 583 1.4E-146 T 23-10-2018 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 109 207 6.1E-7 T 23-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 Pfam PF00128 Alpha amylase, catalytic domain 236 543 3.2E-61 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_00955 124d66a6231611b3eabbae3cf76313fa 648 SUPERFAMILY SSF51445 193 586 5.66E-95 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_03845 8d8e0e69931683416610f913104b474a 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 2.7E-31 T 23-10-2018 A3L14_03845 8d8e0e69931683416610f913104b474a 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 A3L14_03845 8d8e0e69931683416610f913104b474a 214 SUPERFAMILY SSF56784 1 212 7.2E-51 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_03845 8d8e0e69931683416610f913104b474a 214 Gene3D G3DSA:3.40.50.1000 2 206 1.2E-50 T 23-10-2018 IPR023214 HAD superfamily A3L14_03845 8d8e0e69931683416610f913104b474a 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.2E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 2.2E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 2.2E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 2.2E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 179 1.1E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 Gene3D G3DSA:1.10.150.520 15 86 1.2E-50 T 23-10-2018 A3L14_03845 8d8e0e69931683416610f913104b474a 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 185 1.6E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_03845 8d8e0e69931683416610f913104b474a 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 206 1.2E-53 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L14_03845 8d8e0e69931683416610f913104b474a 214 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 82 186 2.3E-12 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L14_07380 9f02abd0e96b6863e1e74ba21153fd83 232 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_07380 9f02abd0e96b6863e1e74ba21153fd83 232 Pfam PF00005 ABC transporter 20 155 2.4E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_07380 9f02abd0e96b6863e1e74ba21153fd83 232 SMART SM00382 25 224 3.5E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_07380 9f02abd0e96b6863e1e74ba21153fd83 232 SUPERFAMILY SSF52540 1 217 1.33E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07380 9f02abd0e96b6863e1e74ba21153fd83 232 Gene3D G3DSA:3.40.50.300 1 224 4.6E-47 T 23-10-2018 A3L14_09640 b7446cf2cb3b7782ee22b2ef0f9fd571 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 286 6.3E-48 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A3L14_09640 b7446cf2cb3b7782ee22b2ef0f9fd571 308 Gene3D G3DSA:1.10.4200.10 25 293 3.1E-59 T 23-10-2018 A3L14_03570 a04b6f463b29a218254bb4b3226079dd 461 SMART SM00493 200 269 2.0E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03570 a04b6f463b29a218254bb4b3226079dd 461 SUPERFAMILY SSF56731 199 312 6.02E-11 T 23-10-2018 A3L14_03570 a04b6f463b29a218254bb4b3226079dd 461 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 460 36.348 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A3L14_03570 a04b6f463b29a218254bb4b3226079dd 461 Pfam PF13662 Toprim domain 201 284 1.4E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L14_03570 a04b6f463b29a218254bb4b3226079dd 461 Gene3D G3DSA:3.40.1360.10 198 294 1.2E-12 T 23-10-2018 A3L14_10875 51487dd4a703d1691625573b1d0f3fc4 485 SUPERFAMILY SSF50998 23 225 2.12E-11 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L14_10875 51487dd4a703d1691625573b1d0f3fc4 485 Gene3D G3DSA:2.130.10.10 13 253 9.2E-8 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L14_10875 51487dd4a703d1691625573b1d0f3fc4 485 PIRSF PIRSF016666 1 485 3.0E-240 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L14_10875 51487dd4a703d1691625573b1d0f3fc4 485 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 359 3.4E-149 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L14_02775 bad2566fdc5bf7d777c3799cb1e74cd6 79 SUPERFAMILY SSF54909 2 75 1.21E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_02775 bad2566fdc5bf7d777c3799cb1e74cd6 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.3E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_02775 bad2566fdc5bf7d777c3799cb1e74cd6 79 Gene3D G3DSA:3.30.70.920 1 74 2.5E-21 T 23-10-2018 A3L14_08930 002056f5c90e0221136ffd971a187bd8 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L14_08930 002056f5c90e0221136ffd971a187bd8 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 2.8E-15 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L14_08930 002056f5c90e0221136ffd971a187bd8 188 Gene3D G3DSA:1.20.120.1760 7 188 5.3E-51 T 23-10-2018 A3L14_00285 e6c3a3d2e362e84e5dc93178ea8ee3fe 478 Pfam PF04415 Protein of unknown function (DUF515) 30 477 6.1E-140 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A3L14_07660 8234e58486b60262acbc38ff47bf928d 216 SUPERFAMILY SSF46785 7 95 8.24E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07660 8234e58486b60262acbc38ff47bf928d 216 Pfam PF12840 Helix-turn-helix domain 15 70 8.5E-11 T 23-10-2018 A3L14_07660 8234e58486b60262acbc38ff47bf928d 216 Gene3D G3DSA:1.10.10.10 9 92 1.3E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04745 86fe98e19553d579636fab1ea86fdcc7 115 Gene3D G3DSA:3.40.30.10 21 109 3.3E-16 T 23-10-2018 A3L14_04745 86fe98e19553d579636fab1ea86fdcc7 115 SUPERFAMILY SSF52833 6 112 3.54E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_04745 86fe98e19553d579636fab1ea86fdcc7 115 Pfam PF13192 Thioredoxin domain 32 106 2.0E-10 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 Gene3D G3DSA:3.40.1280.10 1 177 2.5E-80 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 PIRSF PIRSF016123 1 177 3.5E-86 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 177 3.0E-57 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 174 2.7E-51 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 SUPERFAMILY SSF75217 1 174 2.35E-69 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_08925 6e089cc35efabf3ebf1a1d895f8ba2f3 177 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 176 44.005 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 SMART SM00382 44 194 1.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 Gene3D G3DSA:3.40.50.300 41 251 1.1E-87 T 23-10-2018 A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 3.5E-128 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 Pfam PF03308 ArgK protein 18 282 1.1E-101 T 23-10-2018 A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 Gene3D G3DSA:1.20.5.170 1 40 1.8E-6 T 23-10-2018 A3L14_08510 c18437f2ce0f209cfbcccb51e0e4b39e 319 SUPERFAMILY SSF52540 2 310 3.08E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 Gene3D G3DSA:3.40.30.10 1 144 1.1E-44 T 23-10-2018 A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 Hamap MF_00401 Peroxiredoxin. 2 215 50.471 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 7.2E-8 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 Pfam PF00578 AhpC/TSA family 4 134 1.5E-31 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 Gene3D G3DSA:3.30.1020.10 145 216 1.9E-33 T 23-10-2018 A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 SUPERFAMILY SSF52833 1 215 4.15E-62 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_06925 2c8dc3470c1ad1d76f5b513049134797 216 PIRSF PIRSF000239 1 215 1.3E-68 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 SUPERFAMILY SSF50677 203 401 4.4E-54 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Gene3D G3DSA:1.10.730.10 670 853 9.8E-53 T 23-10-2018 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1059 13.697 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Gene3D G3DSA:3.40.50.620 16 651 4.2E-231 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Gene3D G3DSA:3.90.740.10 199 405 4.2E-231 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 SUPERFAMILY SSF47323 676 915 6.35E-59 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 3.6E-187 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 875 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 SUPERFAMILY SSF47323 984 1050 8.5E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 1.3E-35 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 SUPERFAMILY SSF52374 9 674 5.09E-132 T 23-10-2018 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_00985 3944a6fe634233a93da09b14fd0de060 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 880 13.412 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Gene3D G3DSA:3.40.50.300 682 881 1.3E-44 T 23-10-2018 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Gene3D G3DSA:3.40.50.300 1 217 6.0E-47 T 23-10-2018 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Gene3D G3DSA:1.10.287.510 392 503 5.5E-27 T 23-10-2018 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Pfam PF04423 Rad50 zinc hook motif 424 469 7.7E-15 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 SUPERFAMILY SSF75712 394 492 1.7E-17 T 23-10-2018 A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 SUPERFAMILY SSF52540 1 869 3.56E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 SUPERFAMILY SSF52540 1 290 4.25E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10210 4c074608c2b51ef736edc0de785bbb22 885 Pfam PF13476 AAA domain 5 224 6.4E-22 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain A3L14_06145 bad633b3dd23f0564d268df3acb35d69 416 Gene3D G3DSA:1.10.3210.10 3 288 5.0E-85 T 23-10-2018 A3L14_06145 bad633b3dd23f0564d268df3acb35d69 416 SUPERFAMILY SSF109604 3 412 7.61E-90 T 23-10-2018 A3L14_06145 bad633b3dd23f0564d268df3acb35d69 416 SMART SM00471 48 188 5.2E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L14_06145 bad633b3dd23f0564d268df3acb35d69 416 Pfam PF01966 HD domain 52 179 6.5E-15 T 23-10-2018 IPR006674 HD domain A3L14_05860 20edb631bcd9f7d66922463fd81c06f5 220 Gene3D G3DSA:1.10.150.520 15 84 1.8E-9 T 23-10-2018 A3L14_05860 20edb631bcd9f7d66922463fd81c06f5 220 SUPERFAMILY SSF56784 4 187 2.4E-15 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_05860 20edb631bcd9f7d66922463fd81c06f5 220 Gene3D G3DSA:3.40.50.1000 4 134 1.8E-9 T 23-10-2018 IPR023214 HAD superfamily A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 SMART SM00881 4 98 8.0E-18 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 Pfam PF13380 CoA binding domain 9 129 3.9E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 2.7E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 SUPERFAMILY SSF52210 290 436 9.55E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 SUPERFAMILY SSF51735 2 126 1.5E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 SUPERFAMILY SSF52210 128 283 9.68E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 Gene3D G3DSA:3.40.50.720 1 125 1.3E-29 T 23-10-2018 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 Gene3D G3DSA:3.40.50.261 135 286 4.2E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00065 40d2ee98aa7d717dec69a1fa4de4ba94 438 Gene3D G3DSA:3.40.50.261 287 437 2.1E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_05360 2a95e56564d56524062aa1946151225e 89 Gene3D G3DSA:3.30.70.20 2 89 1.0E-16 T 23-10-2018 A3L14_05360 2a95e56564d56524062aa1946151225e 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_05360 2a95e56564d56524062aa1946151225e 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 70 81 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_05360 2a95e56564d56524062aa1946151225e 89 SUPERFAMILY SSF54862 24 87 2.52E-15 T 23-10-2018 A3L14_05360 2a95e56564d56524062aa1946151225e 89 Pfam PF12838 4Fe-4S dicluster domain 33 81 1.1E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 PIRSF PIRSF019240 1 136 8.9E-26 T 23-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 63 93 1.4E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 SUPERFAMILY SSF89447 12 44 2.35E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 Gene3D G3DSA:2.10.260.10 5 101 5.5E-26 T 23-10-2018 A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 SMART SM00966 63 109 9.9E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 SMART SM00966 13 58 0.8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_11035 061b544bf5651eecb82b6ae701be9209 141 SUPERFAMILY SSF89447 63 95 8.89E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 Hamap MF_00186 Glycerol kinase [glpK]. 4 490 57.377 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 489 7.9E-217 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 357 377 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 Gene3D G3DSA:3.30.420.40 4 249 2.6E-115 T 23-10-2018 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 443 6.6E-53 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 Gene3D G3DSA:3.30.420.40 251 495 7.1E-93 T 23-10-2018 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 SUPERFAMILY SSF53067 6 249 5.96E-95 T 23-10-2018 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 248 8.0E-89 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 SUPERFAMILY SSF53067 252 489 2.73E-82 T 23-10-2018 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 PIRSF PIRSF000538 4 494 2.1E-180 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L14_10705 2cc361ea35d8057510fd6d5a5506b323 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L14_08665 0655b6705b5b1204e6a0c2720c737f06 112 Gene3D G3DSA:1.10.8.140 31 112 1.2E-26 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L14_08665 0655b6705b5b1204e6a0c2720c737f06 112 PIRSF PIRSF015730 1 112 2.4E-34 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L14_08665 0655b6705b5b1204e6a0c2720c737f06 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 1.1E-26 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L14_08665 0655b6705b5b1204e6a0c2720c737f06 112 SUPERFAMILY SSF46950 8 111 1.2E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L14_08665 0655b6705b5b1204e6a0c2720c737f06 112 Hamap MF_00026 DNA-binding protein . 3 112 15.956 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Gene3D G3DSA:2.40.30.20 1 69 6.2E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 1.1E-14 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Gene3D G3DSA:1.10.1140.10 435 585 5.2E-60 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Gene3D G3DSA:2.40.50.100 113 184 6.6E-185 T 23-10-2018 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 SUPERFAMILY SSF50615 1 68 2.62E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Gene3D G3DSA:3.40.50.300 70 434 6.6E-185 T 23-10-2018 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.8E-92 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 1.4E-47 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.712 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 SMART SM00382 223 411 0.0011 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 SUPERFAMILY SSF52540 163 440 7.66E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00725 f3692df6c2dee43992553d97188ce1c0 585 SUPERFAMILY SSF47917 447 552 8.89E-27 T 23-10-2018 A3L14_03715 b7e2c2674c38094accd97378d664c1d3 240 SUPERFAMILY SSF46785 4 97 4.78E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03715 b7e2c2674c38094accd97378d664c1d3 240 Gene3D G3DSA:1.10.10.10 164 232 2.5E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03715 b7e2c2674c38094accd97378d664c1d3 240 SMART SM00418 5 86 2.4E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_03715 b7e2c2674c38094accd97378d664c1d3 240 Gene3D G3DSA:1.10.10.10 2 77 2.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03715 b7e2c2674c38094accd97378d664c1d3 240 Pfam PF12840 Helix-turn-helix domain 5 59 1.6E-8 T 23-10-2018 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 SMART SM01380 7 85 1.0E-18 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 Gene3D G3DSA:3.10.440.10 2 89 6.8E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 SUPERFAMILY SSF54575 6 83 3.14E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 Pfam PF01198 Ribosomal protein L31e 12 79 3.5E-9 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 27 57 2.0E-10 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 ProSitePatterns PS01144 Ribosomal protein L31e signature. 47 61 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08705 02cba83abdf9c8fc1930819562294e6f 89 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 89 22.321 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_00765 b8c5fea06256a98629aa8111d8875eb6 283 Gene3D G3DSA:3.40.50.620 2 163 7.1E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00765 b8c5fea06256a98629aa8111d8875eb6 283 SUPERFAMILY SSF52402 38 228 2.87E-31 T 23-10-2018 A3L14_00765 b8c5fea06256a98629aa8111d8875eb6 283 PIRSF PIRSF036668 1 274 1.9E-126 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related A3L14_00765 b8c5fea06256a98629aa8111d8875eb6 283 Pfam PF06508 Queuosine biosynthesis protein QueC 54 132 2.6E-8 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 Pfam PF01676 Metalloenzyme superfamily 5 401 3.5E-54 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 Gene3D G3DSA:3.30.70.2130 81 230 6.9E-142 T 23-10-2018 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 PIRSF PIRSF006392 1 407 4.0E-155 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 1.5E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 SUPERFAMILY SSF53649 5 404 2.13E-42 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 8.0E-138 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.707 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_04535 3b915acd08198747ef7a985301b876e4 411 Gene3D G3DSA:3.40.720.10 7 396 6.9E-142 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L14_09550 f75b20c2bcea0ead823944566e158ab3 180 SUPERFAMILY SSF47413 82 145 5.63E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_09550 f75b20c2bcea0ead823944566e158ab3 180 SMART SM00530 92 147 6.2E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_09550 f75b20c2bcea0ead823944566e158ab3 180 Pfam PF01381 Helix-turn-helix 97 144 4.0E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_09550 f75b20c2bcea0ead823944566e158ab3 180 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 173 4.0E-21 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A3L14_09550 f75b20c2bcea0ead823944566e158ab3 180 Gene3D G3DSA:1.10.260.40 81 180 1.0E-9 T 23-10-2018 A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 Gene3D G3DSA:3.40.50.300 3 240 2.3E-45 T 23-10-2018 A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 SUPERFAMILY SSF52317 192 368 1.41E-29 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 157.803 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 7.5E-157 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 Gene3D G3DSA:3.40.50.880 247 407 6.6E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 430 4.9E-51 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 SUPERFAMILY SSF52540 1 236 1.63E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06090 2258faf1ee2636d0cb1e197c81507c7a 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 9.0E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_05020 ebc975106e1622a31e93cccc1599fec1 475 Gene3D G3DSA:3.90.1640.30 4 204 1.5E-19 T 23-10-2018 A3L14_05020 ebc975106e1622a31e93cccc1599fec1 475 Gene3D G3DSA:3.10.310.30 335 468 2.0E-9 T 23-10-2018 A3L14_05020 ebc975106e1622a31e93cccc1599fec1 475 SUPERFAMILY SSF64182 7 470 3.35E-65 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L14_05020 ebc975106e1622a31e93cccc1599fec1 475 Pfam PF02272 DHHA1 domain 330 464 1.6E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 202 211 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 Gene3D G3DSA:3.90.1150.10 8 328 2.6E-98 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 Gene3D G3DSA:3.40.640.10 44 252 2.6E-98 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 Pfam PF00155 Aminotransferase class I and II 22 329 1.3E-49 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 331 3.3E-94 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 SUPERFAMILY SSF53383 16 330 2.72E-78 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_07455 73b86f93f218c08c09ca2bd74416956b 339 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 333 53.526 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A3L14_09625 dab8145dbf2992eb1dd2ac3256c0823e 137 Pfam PF02566 OsmC-like protein 32 121 5.1E-15 T 23-10-2018 IPR003718 OsmC/Ohr family A3L14_09625 dab8145dbf2992eb1dd2ac3256c0823e 137 SUPERFAMILY SSF82784 8 134 8.24E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L14_09625 dab8145dbf2992eb1dd2ac3256c0823e 137 Gene3D G3DSA:3.30.300.20 4 133 7.3E-34 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03765 2dfbcfd8f4e8e5d06224d31270350ec3 335 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 3 286 9.9E-97 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern A3L14_03765 2dfbcfd8f4e8e5d06224d31270350ec3 335 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 281 4.0E-73 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L14_03765 2dfbcfd8f4e8e5d06224d31270350ec3 335 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 266 9.4E-54 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 Gene3D G3DSA:3.40.50.261 130 289 1.1E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 SUPERFAMILY SSF52210 292 451 3.01E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 SUPERFAMILY SSF52210 132 288 1.83E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 SUPERFAMILY SSF51735 3 130 1.63E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 1.5E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 Gene3D G3DSA:3.40.50.261 290 458 1.3E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 Pfam PF13380 CoA binding domain 11 135 6.7E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 Gene3D G3DSA:3.40.50.720 3 129 1.4E-45 T 23-10-2018 A3L14_09510 1862b6807e3b37ea8d50de646966f459 458 SMART SM00881 6 100 2.6E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_04010 332b8359eb248f800b50ec09d32edf99 201 SUPERFAMILY SSF55486 60 190 4.55E-15 T 23-10-2018 A3L14_04010 332b8359eb248f800b50ec09d32edf99 201 PIRSF PIRSF005785 15 201 7.5E-61 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L14_04010 332b8359eb248f800b50ec09d32edf99 201 Hamap MF_01842 Archaemetzincin [amzA]. 17 194 36.135 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A3L14_04010 332b8359eb248f800b50ec09d32edf99 201 Gene3D G3DSA:3.40.390.10 41 194 9.0E-49 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L14_04010 332b8359eb248f800b50ec09d32edf99 201 Pfam PF07998 Peptidase family M54 36 194 1.3E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L14_11145 f5ab7c860153986f2b4d7134b7c2e082 435 Pfam PF07282 Putative transposase DNA-binding domain 319 388 6.6E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_11145 f5ab7c860153986f2b4d7134b7c2e082 435 Pfam PF01385 Probable transposase 174 299 1.7E-37 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_11145 f5ab7c860153986f2b4d7134b7c2e082 435 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 346 1.0E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_10645 69c25f583d177dc93ba3edfeff82da08 272 PIRSF PIRSF006648 30 262 1.9E-14 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_10645 69c25f583d177dc93ba3edfeff82da08 272 Pfam PF01061 ABC-2 type transporter 17 227 4.8E-16 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L14_10645 69c25f583d177dc93ba3edfeff82da08 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 8.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_10645 69c25f583d177dc93ba3edfeff82da08 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 8.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_10645 69c25f583d177dc93ba3edfeff82da08 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 8.5E-6 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 155 231 3.7E-7 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 Gene3D G3DSA:3.30.360.10 122 321 3.4E-82 T 23-10-2018 A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 SUPERFAMILY SSF51735 3 142 9.88E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 9.9E-29 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 Gene3D G3DSA:3.40.50.720 3 308 3.4E-82 T 23-10-2018 A3L14_09110 adb4a5b472ae87a945a0938f21f6638c 335 SUPERFAMILY SSF55347 155 308 6.21E-22 T 23-10-2018 A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 6.5E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 PIRSF PIRSF006293 1 238 8.3E-70 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 Gene3D G3DSA:3.40.50.620 1 237 7.9E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 45.511 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 225 3.2E-63 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_09855 df2acfa532448deae184bb7b8ecbe2d0 239 SUPERFAMILY SSF52402 1 235 1.63E-50 T 23-10-2018 A3L14_11500 c07a15f26296c6e158611d63644d52df 142 Gene3D G3DSA:3.90.1170.40 1 136 3.0E-49 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L14_11500 c07a15f26296c6e158611d63644d52df 142 Pfam PF02391 MoaE protein 5 117 1.2E-36 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L14_11500 c07a15f26296c6e158611d63644d52df 142 SUPERFAMILY SSF54690 4 135 2.48E-45 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 Gene3D G3DSA:3.30.1490.20 112 165 3.0E-73 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 SUPERFAMILY SSF52440 3 95 2.01E-30 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 SUPERFAMILY SSF56059 99 310 3.27E-65 T 23-10-2018 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 Pfam PF06849 Protein of unknown function (DUF1246) 3 113 1.9E-32 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 Gene3D G3DSA:3.40.50.20 1 83 7.9E-29 T 23-10-2018 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 Pfam PF06973 Domain of unknown function (DUF1297) 158 310 8.0E-40 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_05520 37dffb0b4142f6baa6e911af1fee4ba4 310 Gene3D G3DSA:3.30.470.20 85 308 3.0E-73 T 23-10-2018 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 Pfam PF00227 Proteasome subunit 33 215 2.1E-64 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 Gene3D G3DSA:3.60.20.10 5 253 4.1E-91 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_02180 615f2d180456854f540cdf374ee30d56 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 4.2E-107 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 SUPERFAMILY SSF56235 7 241 6.92E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_02180 615f2d180456854f540cdf374ee30d56 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L14_02180 615f2d180456854f540cdf374ee30d56 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.727 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L14_09765 634336d3a062637d929254cbed82f4e8 222 Pfam PF06745 KaiC 2 217 2.2E-38 T 23-10-2018 IPR014774 KaiC-like domain A3L14_09765 634336d3a062637d929254cbed82f4e8 222 Gene3D G3DSA:3.40.50.300 1 218 5.2E-43 T 23-10-2018 A3L14_09765 634336d3a062637d929254cbed82f4e8 222 SUPERFAMILY SSF52540 1 215 2.22E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 SUPERFAMILY SSF117070 160 253 1.7E-12 T 23-10-2018 A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 Pfam PF03168 Late embryogenesis abundant protein 187 259 6.1E-8 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 SMART SM00769 165 284 4.7E-4 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 SMART SM00769 29 142 1.9 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 Gene3D G3DSA:2.60.40.10 164 295 1.3E-29 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_00025 6a2d42e3fcf7e7a22803a3a25a3adbf4 302 Gene3D G3DSA:2.60.40.10 30 144 6.8E-11 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_00925 e3e64e674ea29def00ff79a65f63cf0c 134 Hamap MF_00341 UPF0146 protein . 3 132 24.981 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L14_00925 e3e64e674ea29def00ff79a65f63cf0c 134 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 4.0E-37 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L14_00925 e3e64e674ea29def00ff79a65f63cf0c 134 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 130 9.0E-27 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L14_00925 e3e64e674ea29def00ff79a65f63cf0c 134 Gene3D G3DSA:3.40.50.150 1 133 4.9E-23 T 23-10-2018 A3L14_03650 d8e8beba4a8b716ecfcfc522f4cddff3 344 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 10 335 1.1E-97 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L14_03650 d8e8beba4a8b716ecfcfc522f4cddff3 344 Pfam PF16868 NMT1-like family 54 335 2.4E-84 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L14_03650 d8e8beba4a8b716ecfcfc522f4cddff3 344 Gene3D G3DSA:3.40.190.10 49 335 2.5E-98 T 23-10-2018 A3L14_03650 d8e8beba4a8b716ecfcfc522f4cddff3 344 SUPERFAMILY SSF53850 47 336 1.9E-73 T 23-10-2018 A3L14_03650 d8e8beba4a8b716ecfcfc522f4cddff3 344 Gene3D G3DSA:3.40.190.10 135 272 2.5E-98 T 23-10-2018 A3L14_04360 e75f919151fde066c822fd919627d31a 424 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 380 3.6E-125 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A3L14_04360 e75f919151fde066c822fd919627d31a 424 SUPERFAMILY SSF89550 5 227 2.94E-14 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L14_04360 e75f919151fde066c822fd919627d31a 424 Gene3D G3DSA:3.20.20.140 3 234 4.2E-16 T 23-10-2018 A3L14_04360 e75f919151fde066c822fd919627d31a 424 Pfam PF13263 PHP-associated 175 225 5.7E-5 T 23-10-2018 A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 9 35 8.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 140 2.9E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 Gene3D G3DSA:2.160.10.10 3 155 6.3E-46 T 23-10-2018 A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 SUPERFAMILY SSF51161 6 161 5.58E-46 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 114 142 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A3L14_00425 0379167e99f8183649c95ccacb9efbe9 204 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 39 71 9.3E-10 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_10865 f0955b537923be2c2813c70b1ad2a0b1 590 Pfam PF13353 4Fe-4S single cluster domain 142 225 9.4E-7 T 23-10-2018 A3L14_10865 f0955b537923be2c2813c70b1ad2a0b1 590 SUPERFAMILY SSF102114 127 393 1.44E-41 T 23-10-2018 A3L14_10865 f0955b537923be2c2813c70b1ad2a0b1 590 Pfam PF04055 Radical SAM superfamily 142 301 1.2E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_10865 f0955b537923be2c2813c70b1ad2a0b1 590 Gene3D G3DSA:3.20.20.70 125 398 6.2E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_10865 f0955b537923be2c2813c70b1ad2a0b1 590 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_00995 5a49a26f33bbf3aa5b57a58110edd048 276 SUPERFAMILY SSF103481 176 269 3.92E-14 T 23-10-2018 A3L14_00995 5a49a26f33bbf3aa5b57a58110edd048 276 Pfam PF00892 EamA-like transporter family 139 269 9.9E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_00995 5a49a26f33bbf3aa5b57a58110edd048 276 Pfam PF00892 EamA-like transporter family 5 131 3.9E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_00995 5a49a26f33bbf3aa5b57a58110edd048 276 SUPERFAMILY SSF103481 39 133 1.83E-12 T 23-10-2018 A3L14_06260 e23eb373e24433b25b2d928e03864fd7 160 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 38.543 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A3L14_06260 e23eb373e24433b25b2d928e03864fd7 160 SUPERFAMILY SSF55040 12 157 4.45E-51 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06260 e23eb373e24433b25b2d928e03864fd7 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 145 4.9E-53 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06260 e23eb373e24433b25b2d928e03864fd7 160 Pfam PF01967 MoaC family 14 154 4.0E-50 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_06260 e23eb373e24433b25b2d928e03864fd7 160 Gene3D G3DSA:3.30.70.640 1 158 6.7E-66 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L14_08370 e9d724b0d524b0a55f20ff3018570103 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.242 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L14_08370 e9d724b0d524b0a55f20ff3018570103 255 Gene3D G3DSA:3.20.20.370 1 255 2.1E-111 T 23-10-2018 A3L14_08370 e9d724b0d524b0a55f20ff3018570103 255 SUPERFAMILY SSF88713 1 252 1.2E-104 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_08370 e9d724b0d524b0a55f20ff3018570103 255 Pfam PF03746 LamB/YcsF family 3 241 4.1E-105 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L14_02770 777ffdc72fd0891671dd0d50a1433ef5 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 130 3.5E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 SMART SM00195 13 146 2.7E-12 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 Pfam PF00782 Dual specificity phosphatase, catalytic domain 43 145 5.9E-17 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 SUPERFAMILY SSF52799 29 148 1.5E-34 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 SMART SM00404 52 141 4.0E-4 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 91 101 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A3L14_08790 b69e1b18f681c366011e30d66ba1a3df 150 Gene3D G3DSA:3.90.190.10 6 150 9.4E-34 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 Gene3D G3DSA:3.40.50.300 2 84 3.3E-11 T 23-10-2018 A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 Gene3D G3DSA:3.40.50.300 85 160 3.3E-14 T 23-10-2018 A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 SUPERFAMILY SSF52540 3 232 1.09E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 Pfam PF01637 ATPase domain predominantly from Archaea 4 195 2.4E-25 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 Pfam PF03008 Archaea bacterial proteins of unknown function 300 396 7.1E-32 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_06165 c45be5c35f68f3b2b9a8c443d4a970f7 457 SUPERFAMILY SSF46785 230 386 1.18E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05450 d816bd9500bf04d7dd966198843818af 387 SUPERFAMILY SSF103473 3 380 2.75E-49 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_05450 d816bd9500bf04d7dd966198843818af 387 Gene3D G3DSA:1.20.1250.20 2 383 4.0E-45 T 23-10-2018 A3L14_05450 d816bd9500bf04d7dd966198843818af 387 Pfam PF07690 Major Facilitator Superfamily 8 236 6.3E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_03645 65163a2f93ad6216adabaaf1b0dc9b3b 607 Gene3D G3DSA:3.20.20.70 240 540 2.5E-75 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_03645 65163a2f93ad6216adabaaf1b0dc9b3b 607 TIGRFAM TIGR00238 TIGR00238: KamA family protein 182 538 6.2E-114 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A3L14_03645 65163a2f93ad6216adabaaf1b0dc9b3b 607 SUPERFAMILY SSF102114 306 531 1.57E-13 T 23-10-2018 A3L14_10355 07e4478b4ce249db24479fab329fefe2 153 SMART SM00670 4 144 2.1E-8 T 23-10-2018 IPR002716 PIN domain A3L14_10355 07e4478b4ce249db24479fab329fefe2 153 SUPERFAMILY SSF88723 5 146 3.92E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_10355 07e4478b4ce249db24479fab329fefe2 153 Pfam PF01850 PIN domain 6 147 2.8E-23 T 23-10-2018 IPR002716 PIN domain A3L14_10355 07e4478b4ce249db24479fab329fefe2 153 Gene3D G3DSA:3.40.50.1010 5 152 9.8E-18 T 23-10-2018 A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 Gene3D G3DSA:3.30.110.40 1 67 9.5E-7 T 23-10-2018 IPR036868 TusA-like domain superfamily A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 Pfam PF01206 Sulfurtransferase TusA 2 67 2.2E-9 T 23-10-2018 IPR001455 TusA-like domain A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 Gene3D G3DSA:1.10.3910.10 83 153 1.4E-17 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 SUPERFAMILY SSF64307 2 67 4.32E-12 T 23-10-2018 IPR036868 TusA-like domain superfamily A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 SUPERFAMILY SSF140683 87 152 1.28E-16 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A3L14_04780 7f070c415a55a0cae49cfa0f6418f5c3 159 Pfam PF08984 Domain of unknown function (DUF1858) 88 144 1.3E-16 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 A3L14_07025 98f80df3bfa6240e4d70adf6a4c85522 244 SUPERFAMILY SSF81606 13 241 1.07E-54 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A3L14_07025 98f80df3bfa6240e4d70adf6a4c85522 244 Gene3D G3DSA:3.60.40.10 5 243 1.1E-56 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A3L14_07025 98f80df3bfa6240e4d70adf6a4c85522 244 SMART SM00331 10 243 3.4E-29 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A3L14_07025 98f80df3bfa6240e4d70adf6a4c85522 244 SMART SM00332 2 241 1.5E-23 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A3L14_07025 98f80df3bfa6240e4d70adf6a4c85522 244 Pfam PF13672 Protein phosphatase 2C 14 203 3.7E-15 T 23-10-2018 A3L14_03965 8084b91467b9e941f7e07003853f548b 419 Gene3D G3DSA:3.90.550.10 1 224 1.3E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03965 8084b91467b9e941f7e07003853f548b 419 SUPERFAMILY SSF51161 243 409 2.14E-38 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L14_03965 8084b91467b9e941f7e07003853f548b 419 Pfam PF00483 Nucleotidyl transferase 2 232 5.5E-37 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L14_03965 8084b91467b9e941f7e07003853f548b 419 Gene3D G3DSA:2.160.10.10 225 410 9.8E-58 T 23-10-2018 A3L14_03965 8084b91467b9e941f7e07003853f548b 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 398 7.0E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_03965 8084b91467b9e941f7e07003853f548b 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 1.4E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_03965 8084b91467b9e941f7e07003853f548b 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 1.3E-152 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A3L14_03965 8084b91467b9e941f7e07003853f548b 419 SUPERFAMILY SSF53448 2 312 1.69E-70 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_00910 7875a81145e7d685a047f098dd2f77a1 624 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 591 7.9E-253 T 23-10-2018 IPR004814 Oligopeptide transporter OPT A3L14_00910 7875a81145e7d685a047f098dd2f77a1 624 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 10 592 2.3E-121 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L14_00910 7875a81145e7d685a047f098dd2f77a1 624 Pfam PF03169 OPT oligopeptide transporter protein 15 589 7.0E-102 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 SUPERFAMILY SSF81271 309 386 9.94E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 SUPERFAMILY SSF52540 84 323 7.41E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 7.8E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 7.8E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 7.8E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 7.8E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 6.6E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Pfam PF01926 50S ribosome-binding GTPase 84 185 5.3E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Gene3D G3DSA:3.40.50.300 208 311 1.1E-8 T 23-10-2018 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Gene3D G3DSA:3.40.50.300 82 201 3.1E-31 T 23-10-2018 A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 6.6E-18 T 23-10-2018 IPR031662 GTP binding protein, second domain A3L14_09670 ccea3b8b6354d19f3f59abce1a2c57d5 388 Gene3D G3DSA:3.10.20.30 312 388 1.5E-28 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 Gene3D G3DSA:3.40.50.300 1 238 1.0E-77 T 23-10-2018 A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 SMART SM00382 28 211 3.0E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 Gene3D G3DSA:2.40.50.140 288 351 2.6E-29 T 23-10-2018 A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 SUPERFAMILY SSF52540 4 242 3.22E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 SUPERFAMILY SSF50331 237 366 1.92E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 Pfam PF00005 ABC transporter 20 161 4.9E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 Pfam PF08402 TOBE domain 281 358 4.6E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L14_09085 55895756f8b4979c077e69754a9a3f18 367 Gene3D G3DSA:2.40.50.100 239 287 5.0E-10 T 23-10-2018 A3L14_04380 eb7b05fe769b2a1b01007ae66362ed9b 439 Pfam PF00999 Sodium/hydrogen exchanger family 11 404 7.6E-44 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L14_04380 eb7b05fe769b2a1b01007ae66362ed9b 439 Gene3D G3DSA:1.20.1530.20 5 415 4.7E-68 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 Pfam PF01979 Amidohydrolase family 271 388 3.4E-9 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 Pfam PF01979 Amidohydrolase family 49 108 1.7E-10 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 SUPERFAMILY SSF51556 53 335 4.42E-73 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 63.002 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 SUPERFAMILY SSF51338 2 402 5.82E-23 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 391 2.0E-117 T 23-10-2018 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L14_00785 ce1e3f695bb994b99cfd27d4600c79c3 410 Gene3D G3DSA:3.20.20.140 44 407 1.2E-106 T 23-10-2018 A3L14_08955 8fe285f0da475cbe8ccb3d43e795a9f8 406 Gene3D G3DSA:1.20.120.1220 56 177 4.5E-12 T 23-10-2018 A3L14_08955 8fe285f0da475cbe8ccb3d43e795a9f8 406 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 262 370 2.8E-27 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A3L14_11280 2b39558bcd4a720b5bd946481b02a70c 171 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 155 8.7E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11280 2b39558bcd4a720b5bd946481b02a70c 171 SUPERFAMILY SSF56770 35 164 2.62E-51 T 23-10-2018 A3L14_11280 2b39558bcd4a720b5bd946481b02a70c 171 Gene3D G3DSA:3.40.50.12280 11 171 5.0E-50 T 23-10-2018 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 Pfam PF03952 Enolase, N-terminal domain 7 135 7.1E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 SUPERFAMILY SSF51604 139 429 3.01E-125 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 4.9E-198 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 SMART SM01193 7 135 4.4E-95 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 SMART SM01192 140 428 4.6E-205 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 Gene3D G3DSA:3.20.20.120 129 428 2.4E-133 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 1.3E-130 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 Gene3D G3DSA:3.30.390.10 2 128 3.6E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 SUPERFAMILY SSF54826 6 140 9.53E-58 T 23-10-2018 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 Hamap MF_00318 Enolase [eno]. 5 414 46.108 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PIRSF PIRSF001400 3 427 8.4E-196 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 162 175 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 108 124 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 366 383 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 337 351 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 39 53 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 PRINTS PR00148 Enolase signature 314 325 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_11460 77bdec790069ba735bd797e599b51f3a 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 SMART SM00485 1 101 1.3E-48 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 1.1E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 1.1E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 1.1E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 1.1E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 1.1E-32 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 Gene3D G3DSA:1.10.150.20 221 281 5.5E-21 T 23-10-2018 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 Pfam PF00752 XPG N-terminal domain 12 101 8.8E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 1.4E-155 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 Gene3D G3DSA:3.40.50.1010 1 220 2.6E-86 T 23-10-2018 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 Pfam PF00867 XPG I-region 141 236 6.9E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 SUPERFAMILY SSF88723 6 236 3.24E-65 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 145.597 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 SMART SM00279 223 257 1.5E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 SUPERFAMILY SSF47807 221 339 1.44E-32 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A3L14_08650 9aa3fb69b66f3388e961697963b5991d 341 SMART SM00484 140 221 5.5E-37 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 Gene3D G3DSA:3.40.50.300 1 209 2.7E-45 T 23-10-2018 A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 Pfam PF01637 ATPase domain predominantly from Archaea 15 251 1.3E-22 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 SUPERFAMILY SSF52540 1 281 5.51E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 Gene3D G3DSA:1.10.10.10 288 357 6.5E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 Gene3D G3DSA:1.10.8.60 210 287 1.7E-25 T 23-10-2018 A3L14_04945 55d9a71478b5b40415684ee132cdf7ed 357 SUPERFAMILY SSF46785 285 355 7.7E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09265 073fbe96bea8e67c85589d522844a4b3 151 Pfam PF01467 Cytidylyltransferase-like 13 144 1.1E-22 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_09265 073fbe96bea8e67c85589d522844a4b3 151 Gene3D G3DSA:3.40.50.620 1 149 6.3E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_09265 073fbe96bea8e67c85589d522844a4b3 151 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 11 77 2.2E-20 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_09265 073fbe96bea8e67c85589d522844a4b3 151 Hamap MF_02115 FAD synthase [ribL]. 10 150 29.935 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L14_09265 073fbe96bea8e67c85589d522844a4b3 151 SUPERFAMILY SSF52374 10 145 8.59E-28 T 23-10-2018 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 Pfam PF13380 CoA binding domain 12 141 6.8E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 SUPERFAMILY SSF51735 5 136 4.1E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 Gene3D G3DSA:3.40.50.261 137 298 4.2E-63 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 SUPERFAMILY SSF52210 138 297 8.24E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 Gene3D G3DSA:3.40.50.261 299 463 4.5E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 5 454 2.5E-183 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 SUPERFAMILY SSF52210 301 458 5.49E-33 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 Gene3D G3DSA:3.40.50.720 3 136 4.6E-44 T 23-10-2018 A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 158 295 2.0E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L14_08640 bf4bb4c146f48c7b0e12490909a368cf 464 SMART SM00881 8 107 2.6E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_02165 e809ccdaa8b65ee65c47afa7549037b0 105 PIRSF PIRSF029826 1 105 2.3E-38 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L14_02165 e809ccdaa8b65ee65c47afa7549037b0 105 Gene3D G3DSA:1.10.287.1080 1 105 1.4E-32 T 23-10-2018 A3L14_02165 e809ccdaa8b65ee65c47afa7549037b0 105 Pfam PF12643 MazG-like family 31 103 1.6E-20 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L14_02165 e809ccdaa8b65ee65c47afa7549037b0 105 SUPERFAMILY SSF101386 1 104 3.2E-31 T 23-10-2018 A3L14_05620 7ab9f99c2d4f7072f6600f138843920e 193 Gene3D G3DSA:1.10.1660.10 69 131 2.3E-7 T 23-10-2018 A3L14_05620 7ab9f99c2d4f7072f6600f138843920e 193 Pfam PF12728 Helix-turn-helix domain 69 119 2.4E-15 T 23-10-2018 A3L14_05620 7ab9f99c2d4f7072f6600f138843920e 193 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 69 118 1.8E-14 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A3L14_05620 7ab9f99c2d4f7072f6600f138843920e 193 SUPERFAMILY SSF46955 69 122 1.26E-7 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 PIRSF PIRSF036432 2 260 8.6E-98 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 SUPERFAMILY SSF53790 1 258 2.62E-63 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 Gene3D G3DSA:3.40.1010.10 1 114 2.1E-40 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 35.786 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 1.4E-101 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 Gene3D G3DSA:3.30.950.10 115 264 9.5E-54 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A3L14_09950 7c27e3dc0a450dabbad8ac60d6445041 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.1E-22 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A3L14_07345 7a8f4f187c3930864700937b7e616a17 183 PIRSF PIRSF018063 1 168 5.0E-69 T 23-10-2018 IPR014490 DNA-binding protein from starved cells-like A3L14_07345 7a8f4f187c3930864700937b7e616a17 183 Gene3D G3DSA:1.20.1260.10 4 160 8.0E-64 T 23-10-2018 IPR012347 Ferritin-like A3L14_07345 7a8f4f187c3930864700937b7e616a17 183 Pfam PF00210 Ferritin-like domain 21 160 7.7E-23 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A3L14_07345 7a8f4f187c3930864700937b7e616a17 183 SUPERFAMILY SSF47240 4 159 3.48E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 Gene3D G3DSA:3.40.50.720 4 134 4.3E-42 T 23-10-2018 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 SUPERFAMILY SSF52210 136 298 1.3E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 Gene3D G3DSA:3.40.50.261 302 468 1.5E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 Pfam PF13380 CoA binding domain 13 139 2.1E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 Gene3D G3DSA:3.40.50.261 136 300 6.4E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 SMART SM00881 9 107 5.3E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 160 297 5.8E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 SUPERFAMILY SSF51735 6 135 1.88E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00210 643832687b4906f7ce70525cf8ce8a0b 470 SUPERFAMILY SSF52210 304 464 6.28E-36 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_00220 fdcc941dee73c9ed57cbb536af145086 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 144 10.231 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_00220 fdcc941dee73c9ed57cbb536af145086 144 Pfam PF01850 PIN domain 7 138 4.9E-23 T 23-10-2018 IPR002716 PIN domain A3L14_00220 fdcc941dee73c9ed57cbb536af145086 144 Gene3D G3DSA:3.40.50.1010 6 144 5.3E-11 T 23-10-2018 A3L14_00220 fdcc941dee73c9ed57cbb536af145086 144 SMART SM00670 5 136 1.5E-17 T 23-10-2018 IPR002716 PIN domain A3L14_00220 fdcc941dee73c9ed57cbb536af145086 144 SUPERFAMILY SSF88723 6 140 3.64E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08405 ff9ff31aa80d3d0f19a4e899ea7516f8 276 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 105 242 4.1E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L14_08405 ff9ff31aa80d3d0f19a4e899ea7516f8 276 Gene3D G3DSA:1.10.1670.10 215 272 1.8E-8 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L14_08405 ff9ff31aa80d3d0f19a4e899ea7516f8 276 SMART SM00478 109 267 4.2E-20 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L14_08405 ff9ff31aa80d3d0f19a4e899ea7516f8 276 SUPERFAMILY SSF48150 88 266 2.44E-35 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L14_08405 ff9ff31aa80d3d0f19a4e899ea7516f8 276 Gene3D G3DSA:1.10.340.30 97 214 2.5E-25 T 23-10-2018 A3L14_10230 385a9be8f9e9d8e862fae4c59404a4bf 240 SUPERFAMILY SSF52540 8 213 1.28E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10230 385a9be8f9e9d8e862fae4c59404a4bf 240 Pfam PF00005 ABC transporter 18 155 1.1E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_10230 385a9be8f9e9d8e862fae4c59404a4bf 240 SMART SM00382 27 201 4.4E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_10230 385a9be8f9e9d8e862fae4c59404a4bf 240 Gene3D G3DSA:3.40.50.300 6 237 6.8E-64 T 23-10-2018 A3L14_10870 3f3e8e069639e2189392dc1a9f84035c 101 Pfam PF11491 Protein of unknown function (DUF3213) 14 96 3.2E-37 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A3L14_10870 3f3e8e069639e2189392dc1a9f84035c 101 Gene3D G3DSA:3.30.70.1750 7 100 1.5E-30 T 23-10-2018 A3L14_08150 5883230d72622fc4f74c5f875995d50b 396 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 239 312 1.0E-13 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_08150 5883230d72622fc4f74c5f875995d50b 396 Pfam PF01385 Probable transposase 172 273 1.1E-6 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_08150 5883230d72622fc4f74c5f875995d50b 396 Pfam PF07282 Putative transposase DNA-binding domain 298 349 6.9E-13 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_07255 ccab329290694ab951ed45d3b8f30086 117 PIRSF PIRSF021774 1 117 3.9E-22 T 23-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 A3L14_07255 ccab329290694ab951ed45d3b8f30086 117 Pfam PF03625 Domain of unknown function DUF302 39 94 3.3E-17 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L14_07255 ccab329290694ab951ed45d3b8f30086 117 SUPERFAMILY SSF103247 4 116 7.06E-25 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_07255 ccab329290694ab951ed45d3b8f30086 117 Gene3D G3DSA:3.30.310.70 1 117 6.3E-23 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_09305 e47a2a7da57168351133076bcfa45cba 401 Pfam PF07690 Major Facilitator Superfamily 20 355 7.0E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_09305 e47a2a7da57168351133076bcfa45cba 401 Gene3D G3DSA:1.20.1250.20 2 185 5.6E-13 T 23-10-2018 A3L14_09305 e47a2a7da57168351133076bcfa45cba 401 SUPERFAMILY SSF103473 3 389 3.92E-32 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_09305 e47a2a7da57168351133076bcfa45cba 401 Gene3D G3DSA:1.20.1250.20 193 391 3.0E-5 T 23-10-2018 A3L14_08905 0577d03e4c6c5925a2b1776cef38a710 158 SMART SM00670 2 133 2.7E-10 T 23-10-2018 IPR002716 PIN domain A3L14_08905 0577d03e4c6c5925a2b1776cef38a710 158 Gene3D G3DSA:3.40.50.1010 2 144 2.8E-10 T 23-10-2018 A3L14_08905 0577d03e4c6c5925a2b1776cef38a710 158 SUPERFAMILY SSF88723 2 142 2.02E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08905 0577d03e4c6c5925a2b1776cef38a710 158 Pfam PF01850 PIN domain 5 132 4.8E-20 T 23-10-2018 IPR002716 PIN domain A3L14_10525 466fbfdaeca73aa086193473939c8a76 238 SUPERFAMILY SSF75217 3 171 5.76E-32 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_10525 466fbfdaeca73aa086193473939c8a76 238 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 225 2.9E-62 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L14_10525 466fbfdaeca73aa086193473939c8a76 238 Pfam PF00588 SpoU rRNA Methylase family 2 150 1.1E-33 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A3L14_10525 466fbfdaeca73aa086193473939c8a76 238 PIRSF PIRSF004808 1 235 2.9E-73 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L14_10525 466fbfdaeca73aa086193473939c8a76 238 Gene3D G3DSA:3.40.1280.10 1 157 3.6E-49 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L14_00165 0b2ba393de524b23d6f1743fd0d101ca 183 SUPERFAMILY SSF52949 4 180 5.05E-49 T 23-10-2018 A3L14_00165 0b2ba393de524b23d6f1743fd0d101ca 183 SMART SM00506 3 146 5.7E-52 T 23-10-2018 IPR002589 Macro domain A3L14_00165 0b2ba393de524b23d6f1743fd0d101ca 183 Pfam PF01661 Macro domain 20 145 9.9E-35 T 23-10-2018 IPR002589 Macro domain A3L14_00165 0b2ba393de524b23d6f1743fd0d101ca 183 Gene3D G3DSA:3.40.220.10 1 180 2.6E-53 T 23-10-2018 A3L14_08580 05b5d0d150fbfc574999093250a26460 345 Gene3D G3DSA:3.40.50.2000 173 314 1.3E-31 T 23-10-2018 A3L14_08580 05b5d0d150fbfc574999093250a26460 345 Gene3D G3DSA:3.40.50.2000 1 172 2.5E-41 T 23-10-2018 A3L14_08580 05b5d0d150fbfc574999093250a26460 345 Pfam PF13439 Glycosyltransferase Family 4 14 169 1.0E-31 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L14_08580 05b5d0d150fbfc574999093250a26460 345 Pfam PF13692 Glycosyl transferases group 1 179 306 2.0E-24 T 23-10-2018 A3L14_08580 05b5d0d150fbfc574999093250a26460 345 SUPERFAMILY SSF53756 5 342 2.51E-78 T 23-10-2018 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Gene3D G3DSA:3.40.50.10050 335 443 1.8E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Gene3D G3DSA:2.40.30.10 214 324 3.2E-41 T 23-10-2018 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Pfam PF11987 Translation-initiation factor 2 337 432 1.2E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 1 582 40.586 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 SUPERFAMILY SSF52540 6 274 1.17E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 SUPERFAMILY SSF52156 320 446 1.28E-34 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Pfam PF00009 Elongation factor Tu GTP binding domain 21 200 3.3E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 150 1.9E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 5 580 1.4E-229 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Gene3D G3DSA:2.40.30.10 452 542 8.7E-31 T 23-10-2018 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Pfam PF14578 Elongation factor Tu domain 4 453 539 4.0E-29 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 SUPERFAMILY SSF50447 451 578 9.03E-26 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Gene3D G3DSA:3.40.50.300 5 213 6.2E-53 T 23-10-2018 A3L14_07810 4dc2f46537b475005909aaa555f4d5f7 583 Pfam PF03144 Elongation factor Tu domain 2 233 311 4.3E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L14_05410 eab1c2966c25afad2a7590230ad36fb9 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 266 3.3E-32 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A3L14_05410 eab1c2966c25afad2a7590230ad36fb9 327 SUPERFAMILY SSF53807 25 289 1.08E-40 T 23-10-2018 A3L14_05410 eab1c2966c25afad2a7590230ad36fb9 327 Gene3D G3DSA:3.40.50.1980 25 187 4.1E-28 T 23-10-2018 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 4.9E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 5.9E-85 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 58.306 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 SUPERFAMILY SSF54211 3 180 1.14E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 Pfam PF08544 GHMP kinases C terminal 244 310 5.3E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 Gene3D G3DSA:3.30.230.10 1 182 9.8E-50 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 SUPERFAMILY SSF55060 183 329 1.6E-34 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 Gene3D G3DSA:3.30.70.890 187 319 4.0E-40 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.0E-29 T 23-10-2018 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.0E-29 T 23-10-2018 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.0E-29 T 23-10-2018 A3L14_02855 77c4617114b641d67e9b0259fb47d5da 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.0E-29 T 23-10-2018 A3L14_08360 c0c1ef5c4ab5dc3442dbfe2cdd0578f7 125 Pfam PF01850 PIN domain 2 115 7.2E-19 T 23-10-2018 IPR002716 PIN domain A3L14_08360 c0c1ef5c4ab5dc3442dbfe2cdd0578f7 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 121 11.71 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_08360 c0c1ef5c4ab5dc3442dbfe2cdd0578f7 125 Gene3D G3DSA:3.40.50.1010 1 121 9.5E-31 T 23-10-2018 A3L14_08360 c0c1ef5c4ab5dc3442dbfe2cdd0578f7 125 SUPERFAMILY SSF88723 1 121 1.23E-31 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_04195 873213de58c1b53887bb35861522c656 305 Gene3D G3DSA:3.40.50.300 1 239 9.5E-58 T 23-10-2018 A3L14_04195 873213de58c1b53887bb35861522c656 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_04195 873213de58c1b53887bb35861522c656 305 Pfam PF00005 ABC transporter 17 167 3.6E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_04195 873213de58c1b53887bb35861522c656 305 SMART SM00382 26 217 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04195 873213de58c1b53887bb35861522c656 305 SUPERFAMILY SSF52540 2 228 9.27E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09330 8f7cd01559bc5fd919bf00707aa076ec 77 Gene3D G3DSA:1.10.260.40 1 65 1.7E-30 T 23-10-2018 A3L14_09330 8f7cd01559bc5fd919bf00707aa076ec 77 SMART SM00530 4 59 5.0E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_09330 8f7cd01559bc5fd919bf00707aa076ec 77 Pfam PF01381 Helix-turn-helix 5 59 1.6E-19 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_09330 8f7cd01559bc5fd919bf00707aa076ec 77 SUPERFAMILY SSF47413 2 63 2.95E-20 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 SMART SM00385 214 295 1.3E-10 T 23-10-2018 IPR013763 Cyclin-like A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 SMART SM00385 120 201 9.0E-13 T 23-10-2018 IPR013763 Cyclin-like A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 45.707 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 SUPERFAMILY SSF57783 5 50 1.36E-16 T 23-10-2018 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Pfam PF08271 TFIIB zinc-binding 6 47 4.4E-18 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 1.3E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Gene3D G3DSA:1.10.472.10 211 303 1.4E-26 T 23-10-2018 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Gene3D G3DSA:1.10.472.170 6 202 1.0E-65 T 23-10-2018 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 SUPERFAMILY SSF47954 114 207 7.73E-25 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 SUPERFAMILY SSF47954 211 302 9.52E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 3.9E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L14_09185 f6b65df4bc811995480985b2c275f25e 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 1.7E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 Gene3D G3DSA:3.50.50.60 4 403 9.6E-137 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.1E-5 T 23-10-2018 A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.1E-5 T 23-10-2018 A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 62 9.5E-12 T 23-10-2018 A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 SUPERFAMILY SSF51905 1 390 3.89E-35 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10735 0c22863d22ac037270d478d65bd25c44 420 Gene3D G3DSA:3.90.660.50 83 359 9.6E-137 T 23-10-2018 A3L14_04510 52030663b6885af88effcd62de71067e 315 Gene3D G3DSA:3.40.50.1370 138 297 8.9E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 6.8E-145 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L14_04510 52030663b6885af88effcd62de71067e 315 Gene3D G3DSA:3.40.50.1370 10 307 8.9E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.147 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A3L14_04510 52030663b6885af88effcd62de71067e 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 3.1E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 SUPERFAMILY SSF53671 4 313 2.1E-116 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_04510 52030663b6885af88effcd62de71067e 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 1.1E-65 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 Gene3D G3DSA:3.40.50.10860 36 180 5.8E-66 T 23-10-2018 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 Gene3D G3DSA:3.40.50.720 182 418 2.1E-95 T 23-10-2018 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 7.1E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 PIRSF PIRSF000185 1 418 6.2E-172 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 SUPERFAMILY SSF51735 182 417 2.45E-80 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 SMART SM00839 184 415 1.4E-95 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 7.7E-75 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 SUPERFAMILY SSF53223 4 184 1.63E-66 T 23-10-2018 A3L14_03020 6fec7eb62063f5da3807a32f1264444d 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 2.6E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L14_09180 1c7939c931bb9715696e42821f5dbd18 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 158 6.3E-34 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L14_09180 1c7939c931bb9715696e42821f5dbd18 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 4.2E-25 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L14_09180 1c7939c931bb9715696e42821f5dbd18 164 SUPERFAMILY SSF56300 2 163 5.89E-37 T 23-10-2018 A3L14_09180 1c7939c931bb9715696e42821f5dbd18 164 Gene3D G3DSA:3.60.21.10 1 163 4.1E-40 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_06155 e8a592d6a0083d14c0f72fe18ef4d023 176 SUPERFAMILY SSF55729 2 173 5.59E-44 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_06155 e8a592d6a0083d14c0f72fe18ef4d023 176 Gene3D G3DSA:3.40.630.30 4 173 3.0E-46 T 23-10-2018 A3L14_06155 e8a592d6a0083d14c0f72fe18ef4d023 176 Pfam PF13302 Acetyltransferase (GNAT) domain 18 149 5.4E-29 T 23-10-2018 IPR000182 GNAT domain A3L14_07215 8c7bcc092e982ecd36ff4447e27b9987 174 SUPERFAMILY SSF47240 1 161 8.34E-62 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07215 8c7bcc092e982ecd36ff4447e27b9987 174 Pfam PF00210 Ferritin-like domain 7 142 2.4E-46 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A3L14_07215 8c7bcc092e982ecd36ff4447e27b9987 174 Gene3D G3DSA:1.20.1260.10 1 174 4.0E-58 T 23-10-2018 IPR012347 Ferritin-like A3L14_09620 3b56be2b69f31716cfb0580676cc6cf4 280 SMART SM00729 18 225 6.5E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_09620 3b56be2b69f31716cfb0580676cc6cf4 280 SUPERFAMILY SSF102114 10 222 1.28E-15 T 23-10-2018 A3L14_09620 3b56be2b69f31716cfb0580676cc6cf4 280 Pfam PF04055 Radical SAM superfamily 23 187 3.3E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_09620 3b56be2b69f31716cfb0580676cc6cf4 280 Gene3D G3DSA:3.80.30.30 51 255 1.0E-13 T 23-10-2018 A3L14_05345 67c3b3e9a02cd14f50accfd5d8ac1bfa 170 SUPERFAMILY SSF53323 2 167 4.18E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_05345 67c3b3e9a02cd14f50accfd5d8ac1bfa 170 Gene3D G3DSA:3.40.920.10 1 170 1.2E-53 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_05345 67c3b3e9a02cd14f50accfd5d8ac1bfa 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 8.1E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_04285 6a52bb7e6096492c4da43a59700e2376 98 Gene3D G3DSA:2.30.30.70 2 97 2.8E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04285 6a52bb7e6096492c4da43a59700e2376 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04285 6a52bb7e6096492c4da43a59700e2376 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.03 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A3L14_04285 6a52bb7e6096492c4da43a59700e2376 98 Pfam PF01157 Ribosomal protein L21e 6 95 9.4E-32 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_04285 6a52bb7e6096492c4da43a59700e2376 98 SUPERFAMILY SSF50104 6 96 5.11E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 Gene3D G3DSA:1.10.10.10 5 94 1.3E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 SUPERFAMILY SSF46785 8 94 1.54E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 Gene3D G3DSA:1.10.510.10 203 296 1.8E-15 T 23-10-2018 A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 SUPERFAMILY SSF56112 103 274 8.42E-24 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 Pfam PF09202 Rio2, N-terminal 13 93 6.3E-23 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 Pfam PF01163 RIO1 family 111 287 8.3E-48 T 23-10-2018 A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 Gene3D G3DSA:3.30.200.20 98 196 6.9E-25 T 23-10-2018 A3L14_10010 f5b26567be8b26a6caeb22958df60f74 308 SMART SM00090 68 299 6.3E-81 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L14_00470 660857b8e33e675b32cc75bd6f39635a 65 Pfam PF13469 Sulfotransferase family 7 49 1.5E-8 T 23-10-2018 A3L14_00470 660857b8e33e675b32cc75bd6f39635a 65 Gene3D G3DSA:3.40.50.300 1 64 4.0E-19 T 23-10-2018 A3L14_00470 660857b8e33e675b32cc75bd6f39635a 65 SUPERFAMILY SSF52540 5 60 2.9E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00480 e170a06b794ca65b663e08f0dfcd52b4 409 Pfam PF01943 Polysaccharide biosynthesis protein 9 279 3.7E-29 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L14_00480 e170a06b794ca65b663e08f0dfcd52b4 409 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 331 408 4.1E-18 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L14_09525 5fcd35d56b88bdbc1d7cd633b9e210bd 204 Gene3D G3DSA:3.40.920.10 3 202 6.7E-49 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_09525 5fcd35d56b88bdbc1d7cd633b9e210bd 204 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 196 2.5E-40 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_09525 5fcd35d56b88bdbc1d7cd633b9e210bd 204 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 6 195 5.5E-86 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L14_09525 5fcd35d56b88bdbc1d7cd633b9e210bd 204 SUPERFAMILY SSF53323 6 201 3.53E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_02090 2187190a0fc42bef3640920373783843 235 SUPERFAMILY SSF161098 9 231 4.84E-35 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_02090 2187190a0fc42bef3640920373783843 235 Gene3D G3DSA:1.10.3720.10 3 233 9.5E-32 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_02090 2187190a0fc42bef3640920373783843 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 232 1.2E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 Gene3D G3DSA:3.30.470.20 87 205 4.4E-56 T 23-10-2018 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 19.039 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 Pfam PF01259 SAICAR synthetase 4 204 1.4E-29 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 SUPERFAMILY SSF56104 2 206 8.5E-48 T 23-10-2018 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 Gene3D G3DSA:3.30.200.20 4 86 4.4E-56 T 23-10-2018 A3L14_05515 a64f1a79ab1b69187a1a50b880482a21 219 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_09295 d9b75d7d4c3f8f84ef0dd4ae48f2b691 392 SUPERFAMILY SSF53383 10 391 5.78E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_09295 d9b75d7d4c3f8f84ef0dd4ae48f2b691 392 Gene3D G3DSA:3.40.640.10 65 284 9.2E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_09295 d9b75d7d4c3f8f84ef0dd4ae48f2b691 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L14_09295 d9b75d7d4c3f8f84ef0dd4ae48f2b691 392 Gene3D G3DSA:3.90.1150.10 34 384 9.2E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_09295 d9b75d7d4c3f8f84ef0dd4ae48f2b691 392 Pfam PF00155 Aminotransferase class I and II 34 383 9.5E-76 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 PIRSF PIRSF002155 1 216 7.0E-68 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 Gene3D G3DSA:3.30.190.20 13 213 3.5E-77 T 23-10-2018 A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.146 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 Gene3D G3DSA:3.40.50.790 59 150 3.5E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 1.1E-48 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A3L14_03615 5e071edda7db412e88b956caf6dcd063 216 SUPERFAMILY SSF56808 6 214 2.35E-65 T 23-10-2018 IPR023674 Ribosomal protein L1-like A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 Pfam PF01637 ATPase domain predominantly from Archaea 2 195 4.4E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 SUPERFAMILY SSF46785 238 314 1.62E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 SUPERFAMILY SSF52540 1 237 3.88E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 Pfam PF03008 Archaea bacterial proteins of unknown function 305 399 9.8E-32 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 SUPERFAMILY SSF52980 333 393 1.88E-6 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 Gene3D G3DSA:3.40.50.300 1 74 8.4E-11 T 23-10-2018 A3L14_02450 52125760ba9a7efff76ac5a302e2b04e 456 Gene3D G3DSA:3.40.50.300 75 164 2.0E-15 T 23-10-2018 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 3.1E-189 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 SUPERFAMILY SSF51412 10 475 8.11E-112 T 23-10-2018 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 SUPERFAMILY SSF54631 70 204 1.27E-32 T 23-10-2018 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 Pfam PF00571 CBS domain 100 146 1.0E-12 T 23-10-2018 IPR000644 CBS domain A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 Pfam PF00571 CBS domain 153 205 3.1E-15 T 23-10-2018 IPR000644 CBS domain A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 SMART SM00116 160 208 2.0E-10 T 23-10-2018 IPR000644 CBS domain A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 SMART SM00116 102 150 1.4E-10 T 23-10-2018 IPR000644 CBS domain A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 SMART SM01240 13 471 4.5E-261 T 23-10-2018 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 Gene3D G3DSA:3.20.20.70 4 484 2.5E-198 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 PIRSF PIRSF000130 3 486 2.5E-194 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 3.4E-148 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 79.488 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L14_01315 b2b0c9534c703598c31a58f0dd5bab0b 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 12 216 2.3E-63 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 Gene3D G3DSA:3.40.50.150 1 220 1.8E-96 T 23-10-2018 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 218 41.617 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 215 8.2E-67 T 23-10-2018 A3L14_08965 99d3d5c97c5fb502535b68d6626dd8a1 220 SUPERFAMILY SSF53335 6 214 4.1E-55 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_05270 72f190805aecf9f72d3d235068fa25c3 278 Gene3D G3DSA:1.10.10.10 198 272 1.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_05270 72f190805aecf9f72d3d235068fa25c3 278 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 211 270 3.6E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_05270 72f190805aecf9f72d3d235068fa25c3 278 SUPERFAMILY SSF46785 206 270 3.96E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07440 967ddd9942cbb93092e52b60b6c2bc9e 232 SUPERFAMILY SSF51366 1 224 3.06E-49 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_07440 967ddd9942cbb93092e52b60b6c2bc9e 232 Gene3D G3DSA:3.20.20.70 1 228 3.2E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_07440 967ddd9942cbb93092e52b60b6c2bc9e 232 Pfam PF00977 Histidine biosynthesis protein 3 217 1.2E-54 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L14_07440 967ddd9942cbb93092e52b60b6c2bc9e 232 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 225 28.774 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A3L14_05990 e15b6f5e750ecb6a1574a052d302e0b9 370 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 175 215 2.5E-4 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L14_05990 e15b6f5e750ecb6a1574a052d302e0b9 370 PIRSF PIRSF018978 1 370 9.0E-179 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A3L14_05990 e15b6f5e750ecb6a1574a052d302e0b9 370 Gene3D G3DSA:3.40.1280.30 88 270 6.4E-7 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 6.5E-22 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 SUPERFAMILY SSF53092 6 124 1.06E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 Gene3D G3DSA:3.90.230.10 123 348 2.8E-90 T 23-10-2018 A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 204 220 6.5E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 302 314 6.5E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 Pfam PF00557 Metallopeptidase family M24 132 334 5.5E-70 T 23-10-2018 IPR000994 Peptidase M24 A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 Gene3D G3DSA:3.40.350.10 1 122 7.3E-30 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L14_05865 fdeae091a59ae2c51390a7ed3185e4bb 348 SUPERFAMILY SSF55920 123 347 4.06E-85 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L14_00275 c0095524b7c557b53d99819c2539d13f 357 SUPERFAMILY SSF52540 4 168 2.34E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00275 c0095524b7c557b53d99819c2539d13f 357 Gene3D G3DSA:3.40.50.300 5 162 8.4E-44 T 23-10-2018 A3L14_00275 c0095524b7c557b53d99819c2539d13f 357 Gene3D G3DSA:1.10.1580.10 169 252 3.7E-15 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A3L14_00275 c0095524b7c557b53d99819c2539d13f 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 6.0E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_00960 194833c92f71114052fed80da761c68d 340 Gene3D G3DSA:1.10.10.10 2 99 1.4E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00960 194833c92f71114052fed80da761c68d 340 SUPERFAMILY SSF46785 4 91 2.07E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00960 194833c92f71114052fed80da761c68d 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 3.8E-54 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L14_00960 194833c92f71114052fed80da761c68d 340 SUPERFAMILY SSF159071 255 339 9.29E-19 T 23-10-2018 A3L14_00960 194833c92f71114052fed80da761c68d 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.5E-24 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_03215 83654624011c2015e653a8638eff334a 314 Pfam PF00753 Metallo-beta-lactamase superfamily 18 76 2.5E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_03215 83654624011c2015e653a8638eff334a 314 SUPERFAMILY SSF56281 3 298 2.16E-75 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_03215 83654624011c2015e653a8638eff334a 314 SMART SM00849 19 207 1.8E-5 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_03215 83654624011c2015e653a8638eff334a 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 295 3.1E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L14_03215 83654624011c2015e653a8638eff334a 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 1.6E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_03215 83654624011c2015e653a8638eff334a 314 Gene3D G3DSA:3.60.15.10 1 299 2.6E-84 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_03215 83654624011c2015e653a8638eff334a 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.494 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L14_03860 455c9b7b57a378ccfbfc601e5599392a 170 Pfam PF13184 NusA-like KH domain 57 124 2.3E-11 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A3L14_03860 455c9b7b57a378ccfbfc601e5599392a 170 SMART SM00322 57 119 1.7E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_03860 455c9b7b57a378ccfbfc601e5599392a 170 Gene3D G3DSA:3.30.300.20 42 97 7.6E-10 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L14_03860 455c9b7b57a378ccfbfc601e5599392a 170 SUPERFAMILY SSF54814 40 96 3.34E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_00540 7856c9b71044094e7cf82d569a0d556d 203 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 200 3.3E-47 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_00540 7856c9b71044094e7cf82d569a0d556d 203 Gene3D G3DSA:3.40.50.11570 1 202 5.0E-39 T 23-10-2018 A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 Pfam PF01637 ATPase domain predominantly from Archaea 6 198 2.9E-16 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 Gene3D G3DSA:3.40.50.300 3 164 3.0E-29 T 23-10-2018 A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 Pfam PF03008 Archaea bacterial proteins of unknown function 307 397 5.7E-27 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 SUPERFAMILY SSF52540 4 237 1.08E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 SUPERFAMILY SSF46785 238 316 3.26E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 PRINTS PR01874 DNA repair protein radA signature 14 42 9.2E-5 T 23-10-2018 A3L14_09735 b327ecc244e47f2f41d2c3ec2a50a409 450 PRINTS PR01874 DNA repair protein radA signature 252 275 9.2E-5 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 98 3.3E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L14_08625 e62736031ff41a80befd08b167928da7 836 SMART SM01072 116 200 7.3E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SUPERFAMILY SSF52540 540 818 2.95E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:1.10.8.60 450 528 1.3E-15 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SMART SM00382 579 715 8.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08625 e62736031ff41a80befd08b167928da7 836 SMART SM00382 244 380 8.0E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08625 e62736031ff41a80befd08b167928da7 836 ProSitePatterns PS00674 AAA-protein family signature. 683 701 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:3.40.50.300 206 378 2.3E-83 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SMART SM01073 14 98 8.6E-38 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L14_08625 e62736031ff41a80befd08b167928da7 836 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:1.10.8.60 379 406 2.3E-83 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SUPERFAMILY SSF50692 11 97 2.15E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L14_08625 e62736031ff41a80befd08b167928da7 836 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 4.4E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 583 712 3.3E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SUPERFAMILY SSF54585 98 213 7.52E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:3.40.50.300 537 712 2.5E-75 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 120 200 1.5E-11 T 23-10-2018 IPR004201 CDC48, domain 2 A3L14_08625 e62736031ff41a80befd08b167928da7 836 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 822 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L14_08625 e62736031ff41a80befd08b167928da7 836 SUPERFAMILY SSF52540 206 529 1.47E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:2.40.40.20 8 98 5.9E-33 T 23-10-2018 A3L14_08625 e62736031ff41a80befd08b167928da7 836 Gene3D G3DSA:1.10.8.60 714 822 3.1E-31 T 23-10-2018 A3L14_03945 3489a6e349f47eb5ea0882ba03f3aa15 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03945 3489a6e349f47eb5ea0882ba03f3aa15 130 Gene3D G3DSA:2.40.10.310 61 130 3.4E-32 T 23-10-2018 A3L14_03945 3489a6e349f47eb5ea0882ba03f3aa15 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 1.5E-46 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03945 3489a6e349f47eb5ea0882ba03f3aa15 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.1E-32 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A3L14_03945 3489a6e349f47eb5ea0882ba03f3aa15 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 31.91 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_05390 2c83c93b0aa057c943ed5d690c46ec85 412 Gene3D G3DSA:3.40.50.2300 38 314 3.8E-84 T 23-10-2018 A3L14_05390 2c83c93b0aa057c943ed5d690c46ec85 412 Gene3D G3DSA:3.40.50.2300 140 325 3.8E-84 T 23-10-2018 A3L14_05390 2c83c93b0aa057c943ed5d690c46ec85 412 SUPERFAMILY SSF53822 55 300 8.01E-8 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L14_05390 2c83c93b0aa057c943ed5d690c46ec85 412 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 39 329 5.8E-52 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 282 2.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 SUPERFAMILY SSF52343 99 282 2.36E-30 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 3.7E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 41 53 3.7E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 115 134 3.7E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 149 3.7E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Pfam PF00970 Oxidoreductase FAD-binding domain 15 102 8.6E-9 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 SUPERFAMILY SSF63380 4 107 3.23E-23 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 115 134 3.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 163 3.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 140 149 3.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 224 3.3E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 PIRSF PIRSF006816 5 291 4.1E-84 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Gene3D G3DSA:2.40.30.10 3 103 2.2E-19 T 23-10-2018 A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Gene3D G3DSA:3.40.50.80 105 248 1.1E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Gene3D G3DSA:2.10.240.10 249 283 1.1E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L14_02385 ac1d1381845a09f51fe6d2aad5c7447f 291 Pfam PF00175 Oxidoreductase NAD-binding domain 116 229 5.1E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L14_11515 dc0f643c1a746815ed2229fa6b6ef5cd 88 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 88 3.8E-19 T 23-10-2018 A3L14_11515 dc0f643c1a746815ed2229fa6b6ef5cd 88 SUPERFAMILY SSF54285 1 86 5.61E-24 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L14_11515 dc0f643c1a746815ed2229fa6b6ef5cd 88 Gene3D G3DSA:3.10.20.30 1 88 9.1E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_11515 dc0f643c1a746815ed2229fa6b6ef5cd 88 Pfam PF02597 ThiS family 5 88 2.5E-21 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L14_11515 dc0f643c1a746815ed2229fa6b6ef5cd 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 6.8E-27 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 Gene3D G3DSA:3.40.30.10 66 153 7.3E-32 T 23-10-2018 A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 SUPERFAMILY SSF52833 7 151 7.94E-52 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 8 147 3.6E-43 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 8 147 9.4E-54 T 23-10-2018 A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 Gene3D G3DSA:1.10.10.1590 5 65 3.7E-20 T 23-10-2018 A3L14_02395 c2ec37b5bec7894348b3d5d194e7380b 154 PIRSF PIRSF000216 5 154 1.6E-59 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09290 dcfb9701e65728805e74d5e112112fac 135 Gene3D G3DSA:3.30.2380.10 6 135 2.3E-45 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L14_09290 dcfb9701e65728805e74d5e112112fac 135 Pfam PF08617 Kinase binding protein CGI-121 38 98 4.5E-5 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 A3L14_09290 dcfb9701e65728805e74d5e112112fac 135 SUPERFAMILY SSF143870 8 127 2.62E-23 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L14_05380 01a7284259b65991514334cfa135d639 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 298 2.6E-108 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L14_05380 01a7284259b65991514334cfa135d639 301 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 1.5E-79 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 Pfam PF02881 SRP54-type protein, helical bundle domain 5 78 2.3E-14 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 SMART SM00962 104 299 6.6E-114 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 Gene3D G3DSA:3.40.50.300 90 298 1.4E-85 T 23-10-2018 A3L14_05380 01a7284259b65991514334cfa135d639 301 Gene3D G3DSA:1.20.120.140 3 87 1.0E-21 T 23-10-2018 A3L14_05380 01a7284259b65991514334cfa135d639 301 SMART SM00382 103 298 3.2E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05380 01a7284259b65991514334cfa135d639 301 SMART SM00963 1 85 6.3E-16 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 58.678 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L14_05380 01a7284259b65991514334cfa135d639 301 SUPERFAMILY SSF47364 1 89 2.09E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L14_05380 01a7284259b65991514334cfa135d639 301 SUPERFAMILY SSF52540 102 299 5.85E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 SUPERFAMILY SSF52540 1 226 4.97E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 Gene3D G3DSA:3.40.50.300 1 240 4.3E-73 T 23-10-2018 A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 Pfam PF00005 ABC transporter 17 162 5.0E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 194 3.1E-69 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 A3L14_03275 43c065c0153ef45469aff7ff185fd7e3 270 SMART SM00382 26 217 7.5E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_04640 e6b38309c9a7bb21ce95a3b0e9665ffb 199 SUPERFAMILY SSF109755 2 198 4.81E-36 T 23-10-2018 A3L14_04640 e6b38309c9a7bb21ce95a3b0e9665ffb 199 Gene3D G3DSA:1.20.58.220 1 199 1.2E-35 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_04640 e6b38309c9a7bb21ce95a3b0e9665ffb 199 Pfam PF01895 PhoU domain 117 189 1.8E-10 T 23-10-2018 IPR026022 PhoU domain A3L14_04640 e6b38309c9a7bb21ce95a3b0e9665ffb 199 Pfam PF01895 PhoU domain 17 96 2.8E-7 T 23-10-2018 IPR026022 PhoU domain A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Gene3D G3DSA:3.40.50.620 163 362 8.0E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Gene3D G3DSA:3.30.2300.10 78 151 5.4E-21 T 23-10-2018 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 SUPERFAMILY SSF143437 1 161 9.24E-41 T 23-10-2018 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Gene3D G3DSA:3.30.70.1510 1 77 5.6E-21 T 23-10-2018 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Pfam PF02926 THUMP domain 26 152 1.3E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 2 336 6.7E-97 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 363 108.853 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 SMART SM00981 67 153 2.0E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 353 1.4E-51 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L14_07220 935dac48a3aec03d6e157960c7020bf7 363 SUPERFAMILY SSF52402 162 362 2.43E-45 T 23-10-2018 A3L14_10885 55730cc94cf17473cc9423e95161b407 224 Pfam PF04172 LrgB-like family 9 221 4.0E-72 T 23-10-2018 IPR007300 CidB/LrgB family A3L14_10885 55730cc94cf17473cc9423e95161b407 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 223 2.9E-80 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A3L14_07690 b111b44d9a1ac3b8ee039da3cc63850a 378 Gene3D G3DSA:1.20.1090.10 185 378 4.4E-54 T 23-10-2018 A3L14_07690 b111b44d9a1ac3b8ee039da3cc63850a 378 Gene3D G3DSA:3.40.50.1970 1 183 8.4E-42 T 23-10-2018 A3L14_07690 b111b44d9a1ac3b8ee039da3cc63850a 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 2.8E-95 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L14_07690 b111b44d9a1ac3b8ee039da3cc63850a 378 SUPERFAMILY SSF56796 2 377 1.96E-96 T 23-10-2018 A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 SUPERFAMILY SSF88723 1 130 3.36E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 SUPERFAMILY SSF52540 134 439 1.1E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 SUPERFAMILY SSF54814 465 521 2.42E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 Pfam PF01850 PIN domain 6 117 6.1E-7 T 23-10-2018 IPR002716 PIN domain A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 Pfam PF00437 Type II/IV secretion system protein 213 370 1.6E-8 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 Gene3D G3DSA:3.40.50.300 232 391 6.9E-17 T 23-10-2018 A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 SMART SM00670 2 115 2.8E-20 T 23-10-2018 IPR002716 PIN domain A3L14_08555 9589743ffb9983fb8efbe35c906ac366 602 Gene3D G3DSA:3.40.50.1010 1 127 2.4E-33 T 23-10-2018 A3L14_06820 8d6b0dcac479289500011d7ec1fce21e 188 SUPERFAMILY SSF48317 28 182 7.85E-27 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L14_06820 8d6b0dcac479289500011d7ec1fce21e 188 SMART SM00014 79 180 3.4E-5 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L14_06820 8d6b0dcac479289500011d7ec1fce21e 188 Gene3D G3DSA:1.20.144.10 111 184 5.6E-11 T 23-10-2018 A3L14_06820 8d6b0dcac479289500011d7ec1fce21e 188 Gene3D G3DSA:1.20.144.10 4 108 3.3E-5 T 23-10-2018 A3L14_06820 8d6b0dcac479289500011d7ec1fce21e 188 Pfam PF01569 PAP2 superfamily 80 173 9.0E-11 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 PIRSF PIRSF005622 1 367 2.2E-143 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 Pfam PF01924 Hydrogenase formation hypA family 10 364 4.0E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 Gene3D G3DSA:3.40.50.11740 59 300 2.1E-111 T 23-10-2018 A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 Gene3D G3DSA:1.10.10.2140 315 367 3.4E-25 T 23-10-2018 A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 Gene3D G3DSA:3.40.50.11750 15 260 2.1E-111 T 23-10-2018 A3L14_03170 83fdb347c3d814312dce14739ff18ef8 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 4 364 4.3E-132 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 SUPERFAMILY SSF51366 24 309 2.31E-56 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 PIRSF PIRSF029271 3 335 1.5E-145 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 52.83 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 5.8E-7 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 Gene3D G3DSA:3.20.20.70 1 316 6.4E-150 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 Pfam PF01680 SOR/SNZ family 13 213 3.6E-94 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01340 7def9d1276191f231362e0775fe1c478 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 1.8E-142 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 SUPERFAMILY SSF53706 11 563 1.06E-194 T 23-10-2018 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Pfam PF01568 Molydopterin dinucleotide binding domain 561 659 4.1E-22 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 14 56 3.7E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Gene3D G3DSA:2.40.40.20 548 670 1.0E-34 T 23-10-2018 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Pfam PF00384 Molybdopterin oxidoreductase 61 480 1.7E-89 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Gene3D G3DSA:3.40.50.740 66 525 9.2E-172 T 23-10-2018 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 SMART SM00926 8 58 1.5E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 13 665 4.4E-267 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 SUPERFAMILY SSF50692 533 667 2.68E-37 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Gene3D G3DSA:3.40.228.10 138 335 9.2E-172 T 23-10-2018 A3L14_01350 1c2be556f2ea098cc442283fc6705b59 671 Gene3D G3DSA:2.20.25.90 11 58 7.6E-9 T 23-10-2018 A3L14_11385 0faacab793589592a62eb605501969a3 147 Pfam PF02915 Rubrerythrin 20 143 5.5E-12 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_11385 0faacab793589592a62eb605501969a3 147 Gene3D G3DSA:1.20.1260.10 8 145 2.8E-24 T 23-10-2018 IPR012347 Ferritin-like A3L14_11385 0faacab793589592a62eb605501969a3 147 SUPERFAMILY SSF47240 15 143 2.95E-21 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 Gene3D G3DSA:3.40.50.300 230 449 2.7E-49 T 23-10-2018 A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 PRINTS PR01874 DNA repair protein radA signature 55 72 8.3E-11 T 23-10-2018 A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 PRINTS PR01874 DNA repair protein radA signature 154 182 8.3E-11 T 23-10-2018 A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 PRINTS PR01874 DNA repair protein radA signature 13 41 8.3E-11 T 23-10-2018 A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 Pfam PF06745 KaiC 5 222 1.7E-51 T 23-10-2018 IPR014774 KaiC-like domain A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 Pfam PF06745 KaiC 240 448 2.2E-30 T 23-10-2018 IPR014774 KaiC-like domain A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 PIRSF PIRSF039117 1 449 2.2E-115 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 SUPERFAMILY SSF52540 234 447 4.64E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 SUPERFAMILY SSF52540 4 226 2.47E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 SMART SM00382 256 410 9.4E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 SMART SM00382 21 185 0.45 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01720 a5a9b72c721630467e95df1a4e5a1364 449 Gene3D G3DSA:3.40.50.300 2 224 1.5E-49 T 23-10-2018 A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.4E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 Pfam PF00106 short chain dehydrogenase 2 183 4.0E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 SUPERFAMILY SSF51735 2 212 2.56E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07180 dc548de85e3acaaeee518ff5158d6497 230 Gene3D G3DSA:3.40.50.720 1 230 4.0E-63 T 23-10-2018 A3L14_10605 49d5750231bfab0b395dc3ac0095ee5d 331 Gene3D G3DSA:3.40.50.970 13 97 5.8E-10 T 23-10-2018 A3L14_10605 49d5750231bfab0b395dc3ac0095ee5d 331 Gene3D G3DSA:3.40.50.970 98 324 2.9E-69 T 23-10-2018 A3L14_10605 49d5750231bfab0b395dc3ac0095ee5d 331 SUPERFAMILY SSF52518 12 317 4.91E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_10605 49d5750231bfab0b395dc3ac0095ee5d 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 2.6E-25 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_00260 74cc4463ec6fbf7c4dc5168bc786fa42 583 Pfam PF03169 OPT oligopeptide transporter protein 24 575 1.4E-62 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L14_00260 74cc4463ec6fbf7c4dc5168bc786fa42 583 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 4.9E-8 T 23-10-2018 A3L14_00260 74cc4463ec6fbf7c4dc5168bc786fa42 583 PRINTS PR00173 Glutamate-aspartate symporter signature 112 137 4.9E-8 T 23-10-2018 A3L14_00260 74cc4463ec6fbf7c4dc5168bc786fa42 583 PRINTS PR00173 Glutamate-aspartate symporter signature 273 292 4.9E-8 T 23-10-2018 A3L14_00260 74cc4463ec6fbf7c4dc5168bc786fa42 583 PRINTS PR00173 Glutamate-aspartate symporter signature 401 420 4.9E-8 T 23-10-2018 A3L14_00865 295ac14131cf581c628b18aa5c4f7eb3 401 SUPERFAMILY SSF140914 2 249 5.89E-24 T 23-10-2018 A3L14_00865 295ac14131cf581c628b18aa5c4f7eb3 401 Gene3D G3DSA:1.20.930.50 6 224 1.4E-47 T 23-10-2018 A3L14_00865 295ac14131cf581c628b18aa5c4f7eb3 401 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 143 369 5.4E-30 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L14_00865 295ac14131cf581c628b18aa5c4f7eb3 401 Gene3D G3DSA:2.20.20.80 109 171 1.4E-47 T 23-10-2018 A3L14_00865 295ac14131cf581c628b18aa5c4f7eb3 401 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 28.75 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 Gene3D G3DSA:3.30.70.141 1 159 1.9E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 SMART SM00562 6 146 2.4E-82 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 8.7E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 8.7E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 8.7E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 8.7E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 8.7E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 Pfam PF00334 Nucleoside diphosphate kinase 7 143 9.8E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 36.152 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_07820 6b3ae1582f737f573d2e0dde320431ee 170 SUPERFAMILY SSF54919 6 153 2.23E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 SUPERFAMILY SSF54909 65 147 9.92E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 Gene3D G3DSA:1.10.10.10 2 56 5.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.0E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.0E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.0E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 SMART SM00344 5 114 4.3E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.6E-15 T 23-10-2018 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 1.8E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 Gene3D G3DSA:3.30.70.920 59 150 1.7E-22 T 23-10-2018 A3L14_11475 d5ae2bc35f83a884ed134ff6507b2117 150 SUPERFAMILY SSF46785 5 63 6.45E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 Pfam PF10559 Plug domain of Sec61p 38 71 2.0E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 476 20.307 T 23-10-2018 IPR026593 Protein translocase subunit SecY A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 Gene3D G3DSA:1.10.3370.10 26 481 6.0E-178 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 SUPERFAMILY SSF103491 9 467 2.88E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 2.4E-8 T 23-10-2018 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 2.4E-8 T 23-10-2018 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 445 463 2.4E-8 T 23-10-2018 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 2.4E-8 T 23-10-2018 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 PIRSF PIRSF004557 5 481 7.7E-103 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 469 4.3E-92 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_02595 c95ee328a915bbf7e02e8bf1f995484c 481 Pfam PF00344 SecY translocase 72 460 4.6E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_01635 fdb8d11eca808424e480d9b7f112d85a 215 Gene3D G3DSA:3.60.21.10 9 121 5.9E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_01635 fdb8d11eca808424e480d9b7f112d85a 215 PIRSF PIRSF000887 4 214 6.2E-38 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L14_01635 fdb8d11eca808424e480d9b7f112d85a 215 Pfam PF00149 Calcineurin-like phosphoesterase 20 133 4.4E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_01635 fdb8d11eca808424e480d9b7f112d85a 215 SUPERFAMILY SSF56300 20 156 9.19E-15 T 23-10-2018 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 Gene3D G3DSA:3.40.1350.30 113 261 2.2E-99 T 23-10-2018 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 401 411 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 350 379 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 Pfam PF02475 Met-10+ like-protein 273 332 1.1E-8 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 344 418 2.7E-13 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 12 411 6.1E-70 T 23-10-2018 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 SUPERFAMILY SSF53335 61 418 5.38E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 SUPERFAMILY SSF50249 4 59 1.37E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 Gene3D G3DSA:3.40.50.150 74 413 2.2E-99 T 23-10-2018 A3L14_07800 617a43e46ac28fafa8b0acf7d08f31da 420 Gene3D G3DSA:2.40.50.140 2 62 2.6E-15 T 23-10-2018 A3L14_02095 c5e54e98fc5d631ef3cbf15d7c81d7d8 239 Gene3D G3DSA:3.40.50.300 1 237 3.7E-79 T 23-10-2018 A3L14_02095 c5e54e98fc5d631ef3cbf15d7c81d7d8 239 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_02095 c5e54e98fc5d631ef3cbf15d7c81d7d8 239 Pfam PF00005 ABC transporter 18 162 2.2E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_02095 c5e54e98fc5d631ef3cbf15d7c81d7d8 239 SUPERFAMILY SSF52540 3 234 8.06E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02095 c5e54e98fc5d631ef3cbf15d7c81d7d8 239 SMART SM00382 27 211 2.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 9.5E-96 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 SMART SM01211 1 221 1.4E-131 T 23-10-2018 A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 Gene3D G3DSA:3.40.50.880 2 223 6.4E-78 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 44.633 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 PIRSF PIRSF001586 1 223 1.7E-83 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 SUPERFAMILY SSF52317 3 221 5.14E-78 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_01410 b9901e59ea4b227ab43cc878724839b6 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 2.4E-50 T 23-10-2018 A3L14_02890 2f4e3caf37d85bf5055acb65f962923c 343 Pfam PF00348 Polyprenyl synthetase 33 269 5.8E-70 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A3L14_02890 2f4e3caf37d85bf5055acb65f962923c 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L14_02890 2f4e3caf37d85bf5055acb65f962923c 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L14_02890 2f4e3caf37d85bf5055acb65f962923c 343 SUPERFAMILY SSF48576 3 342 1.83E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L14_02890 2f4e3caf37d85bf5055acb65f962923c 343 Gene3D G3DSA:1.10.600.10 1 343 9.7E-135 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L14_02860 29b7837914d47da533f94ddadac57e61 265 Pfam PF00696 Amino acid kinase family 1 236 1.1E-42 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L14_02860 29b7837914d47da533f94ddadac57e61 265 Gene3D G3DSA:3.40.1160.10 1 264 9.3E-63 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_02860 29b7837914d47da533f94ddadac57e61 265 PIRSF PIRSF016496 1 264 4.7E-84 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A3L14_02860 29b7837914d47da533f94ddadac57e61 265 SUPERFAMILY SSF53633 1 261 1.27E-35 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_04180 b7c1e2e3ef4cb1b91223cdaee172eea2 323 Pfam PF00288 GHMP kinases N terminal domain 76 136 6.3E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L14_04180 b7c1e2e3ef4cb1b91223cdaee172eea2 323 Gene3D G3DSA:3.30.230.10 16 141 2.4E-10 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_04180 b7c1e2e3ef4cb1b91223cdaee172eea2 323 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 307 2.0E-47 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L14_04180 b7c1e2e3ef4cb1b91223cdaee172eea2 323 SUPERFAMILY SSF54211 1 146 1.37E-17 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_04180 b7c1e2e3ef4cb1b91223cdaee172eea2 323 PIRSF PIRSF004884 1 309 3.4E-98 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L14_07600 303e3bac9c18fe0497931f3ad73f9f8e 193 Gene3D G3DSA:3.30.420.130 1 112 8.4E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_07600 303e3bac9c18fe0497931f3ad73f9f8e 193 SUPERFAMILY SSF53146 1 107 8.89E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_07600 303e3bac9c18fe0497931f3ad73f9f8e 193 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 105 2.6E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L14_08365 a99931053ae253d1e090ec5b459bf0ad 67 SUPERFAMILY SSF141694 1 61 1.54E-14 T 23-10-2018 A3L14_08365 a99931053ae253d1e090ec5b459bf0ad 67 Gene3D G3DSA:4.10.1150.10 1 67 3.8E-10 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L14_08365 a99931053ae253d1e090ec5b459bf0ad 67 Pfam PF01954 Protein of unknown function DUF104 2 50 2.6E-14 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_08075 d2793796aec5760a8275a324c367951a 354 Gene3D G3DSA:2.40.50.140 289 340 2.7E-7 T 23-10-2018 A3L14_08075 d2793796aec5760a8275a324c367951a 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_08075 d2793796aec5760a8275a324c367951a 354 Gene3D G3DSA:2.40.50.100 238 344 2.7E-7 T 23-10-2018 A3L14_08075 d2793796aec5760a8275a324c367951a 354 SMART SM00382 28 211 4.9E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08075 d2793796aec5760a8275a324c367951a 354 Pfam PF00005 ABC transporter 19 161 2.3E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_08075 d2793796aec5760a8275a324c367951a 354 Gene3D G3DSA:3.40.50.300 1 237 2.3E-78 T 23-10-2018 A3L14_08075 d2793796aec5760a8275a324c367951a 354 SUPERFAMILY SSF50331 237 349 1.8E-13 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L14_08075 d2793796aec5760a8275a324c367951a 354 Pfam PF08402 TOBE domain 276 349 5.8E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L14_08075 d2793796aec5760a8275a324c367951a 354 SUPERFAMILY SSF52540 4 244 4.5E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 SMART SM01130 1 292 1.4E-93 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 Gene3D G3DSA:3.20.20.70 1 292 9.0E-90 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 6.9E-16 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 6.9E-16 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 6.9E-16 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 6.9E-16 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 PIRSF PIRSF001365 1 292 1.5E-79 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 SUPERFAMILY SSF51569 2 291 1.88E-78 T 23-10-2018 A3L14_04950 916035d8651c82669e8b1f47e5f4d128 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 6.7E-61 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L14_03855 4dfe99b1ba5b6dc445016f21bd9b5a23 206 SUPERFAMILY SSF109604 14 205 3.66E-61 T 23-10-2018 A3L14_03855 4dfe99b1ba5b6dc445016f21bd9b5a23 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 95 5.6E-9 T 23-10-2018 IPR006675 HDIG domain A3L14_03855 4dfe99b1ba5b6dc445016f21bd9b5a23 206 Gene3D G3DSA:1.10.3210.50 14 206 6.4E-64 T 23-10-2018 A3L14_03855 4dfe99b1ba5b6dc445016f21bd9b5a23 206 Pfam PF01966 HD domain 35 137 8.0E-20 T 23-10-2018 IPR006674 HD domain A3L14_03855 4dfe99b1ba5b6dc445016f21bd9b5a23 206 SMART SM00471 30 147 1.5E-11 T 23-10-2018 IPR003607 HD/PDEase domain A3L14_06265 603f3d0ce633724158896f08becedf4e 309 SUPERFAMILY SSF52540 4 227 7.28E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06265 603f3d0ce633724158896f08becedf4e 309 SMART SM00382 30 213 4.7E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06265 603f3d0ce633724158896f08becedf4e 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 303 5.7E-9 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L14_06265 603f3d0ce633724158896f08becedf4e 309 Gene3D G3DSA:3.40.50.300 2 239 1.9E-66 T 23-10-2018 A3L14_06265 603f3d0ce633724158896f08becedf4e 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_06265 603f3d0ce633724158896f08becedf4e 309 Pfam PF00005 ABC transporter 22 165 7.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06280 5d316424b0363563c8eb2cf4476c5ece 479 Pfam PF01139 tRNA-splicing ligase RtcB 45 479 7.7E-181 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L14_06280 5d316424b0363563c8eb2cf4476c5ece 479 SUPERFAMILY SSF103365 2 479 2.62E-184 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L14_06280 5d316424b0363563c8eb2cf4476c5ece 479 Gene3D G3DSA:3.90.1860.10 1 479 5.0E-226 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 1.0E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 Pfam PF09153 Domain of unknown function (DUF1938) 1 84 6.7E-23 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 SUPERFAMILY SSF46767 90 169 1.22E-21 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 Gene3D G3DSA:1.10.10.10 89 174 7.2E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 SUPERFAMILY SSF53155 1 88 1.33E-23 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 1.8E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 Gene3D G3DSA:3.30.160.70 1 88 7.2E-21 T 23-10-2018 A3L14_10530 38c2d63c3e7226baf8da832fe860df79 178 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 2.0E-19 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L14_02845 b95341e154371107787d4a2e77e48fa3 124 Pfam PF01909 Nucleotidyltransferase domain 13 51 8.8E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_02845 b95341e154371107787d4a2e77e48fa3 124 Gene3D G3DSA:3.30.460.10 2 96 9.5E-12 T 23-10-2018 A3L14_02845 b95341e154371107787d4a2e77e48fa3 124 SUPERFAMILY SSF81301 7 95 7.8E-15 T 23-10-2018 A3L14_02045 8fbbc1bb144db60ef1b15d0b9e6f1448 392 Gene3D G3DSA:1.20.1250.20 208 385 4.1E-18 T 23-10-2018 A3L14_02045 8fbbc1bb144db60ef1b15d0b9e6f1448 392 Gene3D G3DSA:1.20.1250.20 9 207 8.2E-27 T 23-10-2018 A3L14_02045 8fbbc1bb144db60ef1b15d0b9e6f1448 392 SUPERFAMILY SSF103473 11 385 1.57E-52 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_02045 8fbbc1bb144db60ef1b15d0b9e6f1448 392 Pfam PF07690 Major Facilitator Superfamily 214 389 4.0E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_02045 8fbbc1bb144db60ef1b15d0b9e6f1448 392 Pfam PF07690 Major Facilitator Superfamily 20 186 4.2E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_01770 e9de90d434fea48ecd374bd8670ba70e 256 Gene3D G3DSA:1.10.3210.10 33 197 8.6E-8 T 23-10-2018 A3L14_01770 e9de90d434fea48ecd374bd8670ba70e 256 SUPERFAMILY SSF109604 26 170 6.28E-9 T 23-10-2018 A3L14_01770 e9de90d434fea48ecd374bd8670ba70e 256 SMART SM00471 48 181 0.0016 T 23-10-2018 IPR003607 HD/PDEase domain A3L14_05440 540469176d7a7e69cdad5ba9e59748c4 155 Pfam PF10130 PIN domain 4 124 2.1E-25 T 23-10-2018 IPR002716 PIN domain A3L14_05440 540469176d7a7e69cdad5ba9e59748c4 155 Gene3D G3DSA:3.40.50.1010 1 122 1.8E-5 T 23-10-2018 A3L14_05440 540469176d7a7e69cdad5ba9e59748c4 155 SUPERFAMILY SSF88723 2 120 1.15E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05920 b5378dac2ac4658d3551ed94b471b31f 84 SUPERFAMILY SSF46785 3 64 2.09E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05920 b5378dac2ac4658d3551ed94b471b31f 84 Pfam PF09012 FeoC like transcriptional regulator 14 56 1.2E-5 T 23-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC A3L14_05920 b5378dac2ac4658d3551ed94b471b31f 84 Gene3D G3DSA:1.10.10.10 1 69 7.0E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06445 17d9ef2a756fa54c059bc613ae69694f 213 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 14 210 2.5E-29 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L14_06445 17d9ef2a756fa54c059bc613ae69694f 213 Gene3D G3DSA:3.90.320.10 2 211 3.0E-23 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L14_06445 17d9ef2a756fa54c059bc613ae69694f 213 Pfam PF12705 PD-(D/E)XK nuclease superfamily 59 208 4.0E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L14_02100 bf85400f5ce6c7647d8ee69db54d9ad1 178 SUPERFAMILY SSF52499 4 178 2.62E-54 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L14_02100 bf85400f5ce6c7647d8ee69db54d9ad1 178 Pfam PF00857 Isochorismatase family 5 177 2.9E-44 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L14_02100 bf85400f5ce6c7647d8ee69db54d9ad1 178 Gene3D G3DSA:3.40.50.850 1 178 3.3E-71 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Gene3D G3DSA:3.30.420.350 95 305 4.3E-65 T 23-10-2018 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Gene3D G3DSA:3.30.420.40 9 312 4.3E-65 T 23-10-2018 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Gene3D G3DSA:3.90.870.20 330 534 1.1E-75 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Pfam PF02543 Carbamoyltransferase N-terminus 85 312 1.7E-37 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Pfam PF02543 Carbamoyltransferase N-terminus 2 70 2.1E-8 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 SUPERFAMILY SSF53067 12 315 1.26E-11 T 23-10-2018 A3L14_05215 651bd2a0b304134b4611ea861e77dc23 536 Pfam PF16861 Carbamoyltransferase C-terminus 367 534 2.0E-63 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A3L14_09565 18ee23bd85f7b2b9d8ee07a5b0b108a1 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 111 1.0E-21 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A3L14_09565 18ee23bd85f7b2b9d8ee07a5b0b108a1 134 SUPERFAMILY SSF50249 7 116 3.77E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_09565 18ee23bd85f7b2b9d8ee07a5b0b108a1 134 Gene3D G3DSA:1.10.12.20 3 51 4.4E-6 T 23-10-2018 A3L14_09565 18ee23bd85f7b2b9d8ee07a5b0b108a1 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 2.3E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A3L14_08225 78f7ad5afa735a1e03a313b9379249ec 202 Pfam PF00881 Nitroreductase family 8 181 5.3E-35 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_08225 78f7ad5afa735a1e03a313b9379249ec 202 SUPERFAMILY SSF55469 4 201 1.31E-44 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_08225 78f7ad5afa735a1e03a313b9379249ec 202 Gene3D G3DSA:3.40.109.10 1 201 3.1E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 SMART SM00650 30 193 8.6E-81 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 SUPERFAMILY SSF53335 13 266 2.11E-64 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 14 225 1.2E-54 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.673 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 Gene3D G3DSA:1.10.8.100 195 271 6.2E-9 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 Gene3D G3DSA:3.40.50.150 2 193 2.7E-65 T 23-10-2018 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 263 2.6E-75 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L14_04300 4f548237739b5a80ab62fc9c767d5d30 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A3L14_00605 ef80f022eca4bcefbb7bcec4567bf309 251 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 42 2.8E-5 T 23-10-2018 IPR023833 Signal peptide, camelysin A3L14_00605 ef80f022eca4bcefbb7bcec4567bf309 251 ProSitePatterns PS00018 EF-hand calcium-binding domain. 164 176 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 Pfam PF00271 Helicase conserved C-terminal domain 273 375 1.5E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 SMART SM00490 293 376 8.9E-20 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 Pfam PF00270 DEAD/DEAH box helicase 50 224 1.5E-21 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 SUPERFAMILY SSF52540 57 378 1.03E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 SMART SM00487 44 251 7.2E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 Pfam PF09369 Domain of unknown function (DUF1998) 781 863 4.2E-17 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 Gene3D G3DSA:3.40.50.300 31 242 1.6E-39 T 23-10-2018 A3L14_06350 b7f0e31cf8c6d46862953a0e9a166bf3 898 Gene3D G3DSA:3.40.50.300 253 401 1.8E-24 T 23-10-2018 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 PRINTS PR00148 Enolase signature 92 108 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 PRINTS PR00148 Enolase signature 316 330 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 Gene3D G3DSA:3.30.390.10 1 111 1.6E-20 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L14_02710 e77cb983f246134f25a454612b73db3e 341 Gene3D G3DSA:3.20.20.120 220 339 2.4E-13 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L14_02710 e77cb983f246134f25a454612b73db3e 341 SUPERFAMILY SSF54826 1 123 1.48E-29 T 23-10-2018 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 SMART SM01193 4 119 9.4E-33 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 Pfam PF03952 Enolase, N-terminal domain 38 119 1.0E-22 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 SMART SM01192 124 340 2.6E-13 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_02710 e77cb983f246134f25a454612b73db3e 341 SUPERFAMILY SSF51604 125 337 5.65E-29 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L14_02710 e77cb983f246134f25a454612b73db3e 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 247 334 4.5E-9 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 Pfam PF01050 Mannose-6-phosphate isomerase 305 455 4.9E-67 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 SUPERFAMILY SSF51182 185 459 1.09E-63 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 Gene3D G3DSA:3.90.550.10 1 341 6.8E-110 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 Gene3D G3DSA:2.60.120.10 344 450 3.1E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 458 4.1E-156 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 Pfam PF00483 Nucleotidyl transferase 2 272 6.2E-59 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L14_03255 b1e6e5df13c0bb78d88e176602e3177c 460 SUPERFAMILY SSF53448 1 266 1.35E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_10325 f3737133d8636c4d062366dd439cd831 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 4.6E-27 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 Gene3D G3DSA:3.40.50.1370 135 292 2.0E-122 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 2.4E-49 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 SUPERFAMILY SSF53671 2 306 6.15E-101 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.8E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 5.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 5.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 5.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 5.5E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 Gene3D G3DSA:3.40.50.1370 7 301 2.0E-122 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 5.0E-129 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10325 f3737133d8636c4d062366dd439cd831 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.391 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_09135 9e7a7572b3c3f407576d1a2f7105e11d 306 SUPERFAMILY SSF75005 20 296 6.73E-67 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L14_09135 9e7a7572b3c3f407576d1a2f7105e11d 306 Gene3D G3DSA:2.115.10.20 2 296 7.3E-97 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily A3L14_09135 9e7a7572b3c3f407576d1a2f7105e11d 306 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 26 297 6.2E-77 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L14_09135 9e7a7572b3c3f407576d1a2f7105e11d 306 PIRSF PIRSF016202 4 303 4.8E-97 T 23-10-2018 IPR007184 Mannoside phosphorylase A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 Pfam PF09336 Vps4 C terminal oligomerisation domain 349 392 6.5E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 SUPERFAMILY SSF52540 112 391 6.65E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 Gene3D G3DSA:1.10.8.60 280 372 1.2E-84 T 23-10-2018 A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 SMART SM00382 144 281 8.9E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 Gene3D G3DSA:3.40.50.300 109 388 1.2E-84 T 23-10-2018 A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 148 279 2.1E-38 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_07030 d8142d5fb5f9278e4b87065eeba6c811 393 ProSitePatterns PS00674 AAA-protein family signature. 251 270 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L14_07460 bca2e863a2e078c40f789ef6b3593e29 241 SUPERFAMILY SSF56784 2 205 2.49E-11 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_07145 6408605d48cf9e0f7babc2dd184967a7 189 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 182 7.2E-5 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_07145 6408605d48cf9e0f7babc2dd184967a7 189 PIRSF PIRSF000239 1 189 2.8E-64 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_07145 6408605d48cf9e0f7babc2dd184967a7 189 Gene3D G3DSA:3.40.30.10 1 186 2.6E-67 T 23-10-2018 A3L14_07145 6408605d48cf9e0f7babc2dd184967a7 189 SUPERFAMILY SSF52833 1 188 3.69E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_07145 6408605d48cf9e0f7babc2dd184967a7 189 Pfam PF00578 AhpC/TSA family 4 135 7.0E-41 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 Gene3D G3DSA:3.40.50.1980 250 321 1.8E-19 T 23-10-2018 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 9 252 2.4E-93 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 SUPERFAMILY SSF53720 7 376 2.75E-58 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 Gene3D G3DSA:3.40.50.1980 3 212 1.5E-72 T 23-10-2018 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 311 329 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 170 195 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 9 33 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 199 220 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 270 295 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 107 133 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 80 107 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 PRINTS PR00083 Histidinol dehydrogenase signature 221 240 6.1E-98 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 Pfam PF00815 Histidinol dehydrogenase 255 376 4.7E-38 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 Pfam PF00815 Histidinol dehydrogenase 5 252 2.3E-93 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 199 231 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_07425 9f8043158e56d3c054f01fc7c33655fe 377 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 377 36.486 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 SMART SM00382 34 240 5.3E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 Gene3D G3DSA:3.40.50.300 3 319 3.3E-105 T 23-10-2018 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 Pfam PF00005 ABC transporter 25 182 7.1E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.3E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 9.5E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L14_00805 fa81c586be43eaa16963172e589bfdab 319 SUPERFAMILY SSF52540 33 313 7.38E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07340 38d2a0bda45568ebf58075903522f175 100 Pfam PF02915 Rubrerythrin 24 91 1.7E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_07340 38d2a0bda45568ebf58075903522f175 100 SUPERFAMILY SSF47240 6 86 4.65E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07340 38d2a0bda45568ebf58075903522f175 100 Gene3D G3DSA:1.20.1260.10 6 75 2.5E-10 T 23-10-2018 IPR012347 Ferritin-like A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 314 1.2E-144 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 Pfam PF00696 Amino acid kinase family 2 295 8.7E-30 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PIRSF PIRSF000723 1 314 1.7E-140 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 SUPERFAMILY SSF53633 1 313 8.38E-87 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 Gene3D G3DSA:3.40.1160.10 1 315 2.1E-137 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 5.8E-69 T 23-10-2018 A3L14_10740 288765a800d107d6b8eb4fca1dae51c1 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 5.8E-69 T 23-10-2018 A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 PIRSF PIRSF002825 1 335 4.8E-52 T 23-10-2018 IPR026045 Ferric binding protein A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 Gene3D G3DSA:3.40.190.10 30 306 4.0E-116 T 23-10-2018 A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 SUPERFAMILY SSF53850 24 332 3.63E-80 T 23-10-2018 A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 379 3.9E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 Gene3D G3DSA:3.40.190.10 131 331 4.0E-116 T 23-10-2018 A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 Pfam PF13343 Bacterial extracellular solute-binding protein 77 318 2.8E-31 T 23-10-2018 A3L14_07945 c46daaf3fad75a8b3a186023e64249dd 380 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 2.1E-96 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 SUPERFAMILY SSF88713 3 307 2.0E-69 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 Gene3D G3DSA:2.70.98.10 386 652 1.2E-87 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 3.0E-66 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 SUPERFAMILY SSF74650 386 651 1.1E-98 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 Gene3D G3DSA:3.20.110.20 1 379 2.0E-177 T 23-10-2018 A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 SUPERFAMILY SSF88688 309 381 4.77E-37 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 2.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 380 5.2E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L14_00520 d7df5539974cbc3a408e28b632c61501 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 648 5.2E-77 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A3L14_00140 df2803ab05461dc4a3ecb25406f39717 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 103 1.0E-35 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L14_00140 df2803ab05461dc4a3ecb25406f39717 126 Pfam PF04322 Protein of unknown function (DUF473) 1 113 3.5E-33 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L14_02355 134870c4e2fa02c853aa71acc3092082 232 Gene3D G3DSA:3.40.50.11570 11 219 2.3E-47 T 23-10-2018 A3L14_02355 134870c4e2fa02c853aa71acc3092082 232 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 17 217 3.5E-54 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_02600 c10a02cb0426ceb0723063ed40c90e45 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.627 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L14_02600 c10a02cb0426ceb0723063ed40c90e45 196 SMART SM00382 1 145 0.0081 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_02600 c10a02cb0426ceb0723063ed40c90e45 196 SUPERFAMILY SSF52540 1 188 3.92E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02600 c10a02cb0426ceb0723063ed40c90e45 196 Gene3D G3DSA:3.40.50.300 3 189 3.9E-57 T 23-10-2018 A3L14_02600 c10a02cb0426ceb0723063ed40c90e45 196 Pfam PF13207 AAA domain 8 145 1.0E-36 T 23-10-2018 A3L14_02170 0794673bda8f289d3bd3b6302b9d7fc2 149 Gene3D G3DSA:3.30.428.10 1 142 1.5E-35 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_02170 0794673bda8f289d3bd3b6302b9d7fc2 149 Pfam PF01230 HIT domain 11 100 4.1E-20 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L14_02170 0794673bda8f289d3bd3b6302b9d7fc2 149 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site A3L14_02170 0794673bda8f289d3bd3b6302b9d7fc2 149 SUPERFAMILY SSF54197 2 147 2.78E-36 T 23-10-2018 IPR036265 HIT-like superfamily A3L14_07780 db2e1600e2c6aca4083e591155284c41 141 Gene3D G3DSA:3.40.50.1010 3 128 1.0E-8 T 23-10-2018 A3L14_07780 db2e1600e2c6aca4083e591155284c41 141 Pfam PF10130 PIN domain 6 120 6.5E-24 T 23-10-2018 IPR002716 PIN domain A3L14_07780 db2e1600e2c6aca4083e591155284c41 141 SUPERFAMILY SSF88723 4 125 8.13E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08850 838fe05b145109c944d0a65a04ea8d4e 146 Gene3D G3DSA:1.10.10.10 53 136 1.4E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_08850 838fe05b145109c944d0a65a04ea8d4e 146 SUPERFAMILY SSF46785 59 131 4.82E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08850 838fe05b145109c944d0a65a04ea8d4e 146 Pfam PF03965 Penicillinase repressor 63 121 2.9E-5 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 PRINTS PR01250 Ribosomal protein L34 signature 5 18 7.7E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 PRINTS PR01250 Ribosomal protein L34 signature 18 35 7.7E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 PRINTS PR01250 Ribosomal protein L34 signature 36 46 7.7E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 PRINTS PR01250 Ribosomal protein L34 signature 56 78 7.7E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 Gene3D G3DSA:3.40.1800.40 29 87 3.0E-10 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 Pfam PF01199 Ribosomal protein L34e 3 83 5.4E-25 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02610 20daa1bb33b0e2b32d833be4f160a3d7 89 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 28.96 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09720 302900d33cf96fdb12ead989a7cda0f2 444 Gene3D G3DSA:1.20.1250.20 210 425 6.8E-22 T 23-10-2018 A3L14_09720 302900d33cf96fdb12ead989a7cda0f2 444 Gene3D G3DSA:1.20.1250.20 2 193 1.9E-39 T 23-10-2018 A3L14_09720 302900d33cf96fdb12ead989a7cda0f2 444 SUPERFAMILY SSF103473 5 426 3.14E-67 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_09720 302900d33cf96fdb12ead989a7cda0f2 444 Pfam PF07690 Major Facilitator Superfamily 14 364 3.7E-53 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_01915 3c8e0071d0a718b0398e28c94eb08be9 459 PIRSF PIRSF005353 1 456 3.3E-168 T 23-10-2018 IPR026033 Purine permease PbuG-like A3L14_01915 3c8e0071d0a718b0398e28c94eb08be9 459 Pfam PF00860 Permease family 20 414 7.7E-42 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L14_09915 0061eea6d441556b002ccf5f9df67a7d 231 Gene3D G3DSA:3.40.50.300 5 231 3.6E-53 T 23-10-2018 A3L14_10115 9a396308efe3266273439330501f98e2 211 SUPERFAMILY SSF56281 1 198 5.9E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_10115 9a396308efe3266273439330501f98e2 211 SMART SM00849 7 175 1.2E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_10115 9a396308efe3266273439330501f98e2 211 Pfam PF13483 Beta-lactamase superfamily domain 2 175 1.5E-29 T 23-10-2018 A3L14_10115 9a396308efe3266273439330501f98e2 211 Gene3D G3DSA:3.60.15.10 1 204 5.3E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_00305 d25894b44450faf74ea43ff11e867dc9 300 Pfam PF00482 Type II secretion system (T2SS), protein F 102 226 1.4E-18 T 23-10-2018 IPR018076 Type II secretion system F domain A3L14_00305 d25894b44450faf74ea43ff11e867dc9 300 Gene3D G3DSA:1.20.81.30 88 206 2.0E-8 T 23-10-2018 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.88 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 1.0E-40 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 SUPERFAMILY SSF55174 52 96 1.7E-7 T 23-10-2018 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Gene3D G3DSA:2.30.30.30 179 243 8.3E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Gene3D G3DSA:2.40.50.740 123 177 4.0E-16 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Pfam PF00900 Ribosomal family S4e 96 173 3.1E-22 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 SMART SM00363 44 107 1.2E-9 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 PIRSF PIRSF002116 2 243 1.9E-100 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Pfam PF01479 S4 domain 45 91 3.4E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Gene3D G3DSA:3.10.290.40 1 118 6.6E-50 T 23-10-2018 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02540 3c9e936edf83520b975d487f34daa09b 243 Pfam PF08071 RS4NT (NUC023) domain 4 40 5.3E-17 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 SUPERFAMILY SSF50249 7 87 1.43E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Gene3D G3DSA:3.30.70.1130 173 262 9.2E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Pfam PF00575 S1 RNA binding domain 9 83 3.3E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Gene3D G3DSA:1.10.150.190 86 171 1.3E-32 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 SUPERFAMILY SSF116742 85 174 9.42E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 SMART SM00316 10 83 7.2E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.997 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 7.2E-24 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 Gene3D G3DSA:2.40.50.140 3 85 4.3E-32 T 23-10-2018 A3L14_03305 a257af35a1b2d6cab86c3b715c323e1f 275 SUPERFAMILY SSF110993 176 259 1.31E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L14_09340 09d7e681663e065f2d2222bb17c5b42f 427 Pfam PF12698 ABC-2 family transporter protein 19 401 5.1E-34 T 23-10-2018 A3L14_09340 09d7e681663e065f2d2222bb17c5b42f 427 Gene3D G3DSA:3.40.1710.10 42 202 2.7E-31 T 23-10-2018 A3L14_09050 5d23a753f832e30fe571e96c76ac6f62 131 Pfam PF01957 NfeD-like C-terminal, partner-binding 20 130 7.6E-15 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L14_09050 5d23a753f832e30fe571e96c76ac6f62 131 SUPERFAMILY SSF141322 66 129 1.83E-11 T 23-10-2018 A3L14_09050 5d23a753f832e30fe571e96c76ac6f62 131 Gene3D G3DSA:2.40.50.140 67 131 9.4E-20 T 23-10-2018 A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 Gene3D G3DSA:3.40.630.10 5 356 1.9E-75 T 23-10-2018 A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 SUPERFAMILY SSF55031 167 272 1.5E-13 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 SUPERFAMILY SSF53187 3 366 3.83E-52 T 23-10-2018 A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 Pfam PF07687 Peptidase dimerisation domain 164 264 9.8E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 Pfam PF01546 Peptidase family M20/M25/M40 61 365 4.5E-29 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L14_10470 e5d442deedacf8a95a9da72785bb9e61 368 Gene3D G3DSA:3.30.70.360 167 278 1.9E-75 T 23-10-2018 A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 PIRSF PIRSF005644 2 330 7.6E-95 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 140 2.3E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 SUPERFAMILY SSF56042 146 322 2.84E-40 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 Gene3D G3DSA:3.90.650.10 146 330 3.1E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 Gene3D G3DSA:3.30.1330.10 11 144 3.0E-28 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 SUPERFAMILY SSF55326 5 144 1.48E-26 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_06395 8d44bbf986e8a1adc82d07d5dd76365f 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 310 5.2E-30 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_09965 e6ac409bf7ba65d6513f40d342d7fb89 121 Pfam PF03965 Penicillinase repressor 19 111 5.2E-15 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A3L14_09965 e6ac409bf7ba65d6513f40d342d7fb89 121 Gene3D G3DSA:1.10.10.10 19 85 4.2E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09965 e6ac409bf7ba65d6513f40d342d7fb89 121 SUPERFAMILY SSF46785 17 116 1.07E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03805 b765a8174f3b0b7d100b830e868261b4 183 Pfam PF04434 SWIM zinc finger 45 68 1.4E-6 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A3L14_07515 c0a251771a77b957bd763a48567d2843 576 Pfam PF02554 Carbon starvation protein CstA 1 352 2.0E-109 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A3L14_07515 c0a251771a77b957bd763a48567d2843 576 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 400 521 1.2E-28 T 23-10-2018 IPR025299 CstA, C-terminal domain A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 62 28.055 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 62 4.2E-16 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 61 2.0E-13 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 Gene3D G3DSA:2.20.28.90 1 62 2.7E-31 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 SMART SM01389 4 62 4.4E-29 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L14_01540 7096375a44d951bfe4b6156b5c8309db 62 SUPERFAMILY SSF63393 2 62 1.54E-22 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 2.9E-73 T 23-10-2018 IPR002687 Nop domain A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 SMART SM00931 130 182 1.4E-27 T 23-10-2018 IPR012976 NOSIC A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 Gene3D G3DSA:1.10.287.660 131 243 2.0E-38 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 Gene3D G3DSA:1.10.150.460 161 212 2.0E-38 T 23-10-2018 A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 SUPERFAMILY SSF89124 126 366 9.29E-81 T 23-10-2018 IPR036070 Nop domain superfamily A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 Gene3D G3DSA:1.10.246.90 244 368 1.6E-51 T 23-10-2018 A3L14_09590 dcccab2143a78efbb8469b34c37dcf8a 423 Gene3D G3DSA:3.30.420.220 1 125 7.7E-47 T 23-10-2018 A3L14_06685 86dfc6f659ccfc99031ee2d8a499de7f 153 PIRSF PIRSF000239 4 148 2.2E-23 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_06685 86dfc6f659ccfc99031ee2d8a499de7f 153 Gene3D G3DSA:3.40.30.10 2 150 6.8E-44 T 23-10-2018 A3L14_06685 86dfc6f659ccfc99031ee2d8a499de7f 153 Pfam PF00578 AhpC/TSA family 8 128 1.1E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L14_06685 86dfc6f659ccfc99031ee2d8a499de7f 153 SUPERFAMILY SSF52833 8 149 2.64E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_04335 430e1d13b4bbff72bca1b89f5b429373 240 Gene3D G3DSA:3.20.20.370 1 239 5.6E-39 T 23-10-2018 A3L14_04335 430e1d13b4bbff72bca1b89f5b429373 240 Pfam PF01522 Polysaccharide deacetylase 14 125 1.1E-18 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A3L14_04335 430e1d13b4bbff72bca1b89f5b429373 240 SUPERFAMILY SSF88713 3 232 1.2E-33 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_05590 496ad804b286fc78267d8cccda6757bc 313 SUPERFAMILY SSF52540 25 255 1.06E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06315 cf1a2f65e6288ff976cbdf4f5f6f5bae 221 Pfam PF00535 Glycosyl transferase family 2 9 164 1.5E-35 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_06315 cf1a2f65e6288ff976cbdf4f5f6f5bae 221 SUPERFAMILY SSF53448 6 219 4.57E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_06315 cf1a2f65e6288ff976cbdf4f5f6f5bae 221 Gene3D G3DSA:3.90.550.10 3 221 6.5E-60 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01210 e87a4782ec3f9f36ca4e71250aa9bbd5 331 Pfam PF00483 Nucleotidyl transferase 3 234 8.9E-38 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L14_01210 e87a4782ec3f9f36ca4e71250aa9bbd5 331 SUPERFAMILY SSF53448 1 286 3.38E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01210 e87a4782ec3f9f36ca4e71250aa9bbd5 331 Gene3D G3DSA:2.160.10.10 240 330 3.5E-7 T 23-10-2018 A3L14_01210 e87a4782ec3f9f36ca4e71250aa9bbd5 331 Gene3D G3DSA:3.90.550.10 1 239 7.6E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 Pfam PF04851 Type III restriction enzyme, res subunit 95 231 9.8E-18 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 SUPERFAMILY SSF52540 136 420 1.78E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 Gene3D G3DSA:3.40.50.300 273 454 2.0E-32 T 23-10-2018 A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 SMART SM00487 91 272 1.6E-25 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 SMART SM00490 328 406 1.6E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 Pfam PF00271 Helicase conserved C-terminal domain 308 404 5.7E-10 T 23-10-2018 IPR001650 Helicase, C-terminal A3L14_04210 6d74745ce97d6eeff2d07009adaf5434 464 Gene3D G3DSA:3.40.50.300 84 261 3.1E-34 T 23-10-2018 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 Gene3D G3DSA:1.10.8.800 2 70 2.1E-23 T 23-10-2018 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 Gene3D G3DSA:3.60.21.50 419 673 8.7E-25 T 23-10-2018 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 PIRSF PIRSF000803 31 699 8.6E-179 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 692 32.502 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 437 640 3.0E-16 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 SUPERFAMILY SSF56300 436 664 7.25E-20 T 23-10-2018 A3L14_00105 96ac335aeada8e8beb609a96f263d3e8 702 Gene3D G3DSA:2.40.50.140 339 414 2.0E-5 T 23-10-2018 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 3.0E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 Gene3D G3DSA:3.40.50.720 98 290 4.6E-139 T 23-10-2018 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 60.06 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 SUPERFAMILY SSF52283 2 133 6.62E-42 T 23-10-2018 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 SUPERFAMILY SSF51735 103 290 6.34E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 2.3E-66 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L14_07790 f55c3a778a3b0432f0fd1000abba3dfc 334 Gene3D G3DSA:3.40.50.720 4 317 4.6E-139 T 23-10-2018 A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 Gene3D G3DSA:3.30.230.40 1 75 2.7E-21 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 Gene3D G3DSA:3.30.230.40 76 176 4.9E-33 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 3.7E-39 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 SUPERFAMILY SSF54211 2 73 2.66E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_07430 eca8a55710016620e515bcb4d1888a34 178 SUPERFAMILY SSF54211 75 164 1.01E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 Gene3D G3DSA:3.20.20.70 2 333 2.2E-132 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 1.1E-128 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 Pfam PF08608 Wyosine base formation 255 315 2.8E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 SUPERFAMILY SSF102114 66 283 1.96E-16 T 23-10-2018 A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.214 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L14_01510 4b5eb2c48cfe0106429f0fce3e7631a8 333 Pfam PF04055 Radical SAM superfamily 67 252 1.1E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_07550 789a23466c204c5b2a274c82227c95f8 135 SMART SM00670 1 125 6.4E-10 T 23-10-2018 IPR002716 PIN domain A3L14_07550 789a23466c204c5b2a274c82227c95f8 135 Pfam PF01850 PIN domain 4 125 4.3E-20 T 23-10-2018 IPR002716 PIN domain A3L14_07550 789a23466c204c5b2a274c82227c95f8 135 Gene3D G3DSA:3.40.50.1010 3 131 7.2E-19 T 23-10-2018 A3L14_07550 789a23466c204c5b2a274c82227c95f8 135 SUPERFAMILY SSF88723 1 133 8.97E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 370 386 4.1E-15 T 23-10-2018 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 422 436 4.1E-15 T 23-10-2018 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 688 712 4.1E-15 T 23-10-2018 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 650 662 4.1E-15 T 23-10-2018 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 653 659 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 SUPERFAMILY SSF53335 223 767 2.02E-56 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 Pfam PF07669 Eco57I restriction-modification methylase 650 763 7.0E-15 T 23-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 Pfam PF02384 N-6 DNA Methylase 350 440 3.2E-5 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L14_05430 2cbec6562824f6afdfb99b07008c8d87 1282 Pfam PF12950 TaqI-like C-terminal specificity domain 932 1055 2.5E-7 T 23-10-2018 IPR025931 TaqI-like C-terminal specificity domain A3L14_04885 3899bd5ee2f7926a1f03b7c0fe61ddce 168 Pfam PF01899 Na+/H+ ion antiporter subunit 15 164 9.4E-49 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_04885 3899bd5ee2f7926a1f03b7c0fe61ddce 168 PIRSF PIRSF019239 4 168 7.3E-55 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 SUPERFAMILY SSF48310 207 601 4.19E-103 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 Gene3D G3DSA:1.10.569.10 237 428 6.2E-91 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 SUPERFAMILY SSF56228 1 203 2.49E-65 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 Gene3D G3DSA:1.10.599.10 235 597 6.2E-91 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 219 597 9.5E-97 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 SMART SM00790 4 204 1.6E-112 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 2.2E-67 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_04545 dfaf6dd2668b94f61e3dc44f3f04d694 618 Gene3D G3DSA:3.60.9.10 1 207 1.0E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_06785 d54a0b0c17eb41a98267c0eacb263a20 426 Pfam PF07690 Major Facilitator Superfamily 19 383 1.0E-41 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_06785 d54a0b0c17eb41a98267c0eacb263a20 426 Gene3D G3DSA:1.20.1250.20 6 426 1.5E-77 T 23-10-2018 A3L14_06785 d54a0b0c17eb41a98267c0eacb263a20 426 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A3L14_06785 d54a0b0c17eb41a98267c0eacb263a20 426 SUPERFAMILY SSF103473 4 424 3.01E-75 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_07895 cf96fc8c2e8efb3ce717a0d1d676a906 231 SUPERFAMILY SSF52540 4 220 1.15E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07895 cf96fc8c2e8efb3ce717a0d1d676a906 231 Gene3D G3DSA:3.40.50.300 5 231 6.6E-46 T 23-10-2018 A3L14_07895 cf96fc8c2e8efb3ce717a0d1d676a906 231 Pfam PF06745 KaiC 14 219 1.7E-17 T 23-10-2018 IPR014774 KaiC-like domain A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 1.2E-45 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 Pfam PF01918 Alba 6 66 8.3E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 SUPERFAMILY SSF82704 5 90 8.63E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 Gene3D G3DSA:3.30.110.20 2 90 2.7E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 PIRSF PIRSF028732 1 91 7.0E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 5.0E-40 T 23-10-2018 A3L14_07655 304ec62f72a6bf19dc74df78512cea93 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 27.894 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L14_10720 a0f511739b5c0566520892bec4a06986 121 SUPERFAMILY SSF160148 50 120 3.01E-23 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L14_10720 a0f511739b5c0566520892bec4a06986 121 Gene3D G3DSA:3.10.530.10 51 119 2.2E-24 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L14_10720 a0f511739b5c0566520892bec4a06986 121 SUPERFAMILY SSF53706 5 62 1.24E-6 T 23-10-2018 A3L14_10720 a0f511739b5c0566520892bec4a06986 121 Pfam PF07892 Protein of unknown function (DUF1667) 38 119 5.7E-32 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 SUPERFAMILY SSF53098 1 190 7.28E-49 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 1 188 2.2E-67 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 Hamap MF_00052_A Ribonuclease HII [rnhB]. 1 189 29.989 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 Gene3D G3DSA:3.30.420.10 1 144 5.6E-48 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 Gene3D G3DSA:1.10.10.460 145 189 2.4E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A3L14_06590 3cbaa67ca45e2edbe0f35ab870ef5c4a 216 Pfam PF01351 Ribonuclease HII 1 183 5.9E-42 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A3L14_03610 4d93bff7ae691822538ba3c7ab6dc560 339 Gene3D G3DSA:3.90.105.20 107 186 1.5E-74 T 23-10-2018 A3L14_03610 4d93bff7ae691822538ba3c7ab6dc560 339 Pfam PF00466 Ribosomal protein L10 5 105 1.3E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A3L14_03610 4d93bff7ae691822538ba3c7ab6dc560 339 Gene3D G3DSA:3.30.70.1730 15 210 1.5E-74 T 23-10-2018 A3L14_03610 4d93bff7ae691822538ba3c7ab6dc560 339 SUPERFAMILY SSF160369 5 141 3.01E-24 T 23-10-2018 A3L14_03610 4d93bff7ae691822538ba3c7ab6dc560 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 35.945 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A3L14_11250 ced43bca4008066ba68c043fa8f54d8c 88 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 1.9E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L14_07310 7ca24c259235588625dc067a3986b951 115 SUPERFAMILY SSF49367 5 114 4.32E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L14_07310 7ca24c259235588625dc067a3986b951 115 Gene3D G3DSA:2.60.40.730 1 115 7.5E-52 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L14_07310 7ca24c259235588625dc067a3986b951 115 Pfam PF01880 Desulfoferrodoxin 9 111 7.9E-33 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L14_07310 7ca24c259235588625dc067a3986b951 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 4.1E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L14_01440 c91bc0892e5493238e3c8cb55ac2816c 64 SUPERFAMILY SSF141694 1 40 8.11E-14 T 23-10-2018 A3L14_01440 c91bc0892e5493238e3c8cb55ac2816c 64 Pfam PF01954 Protein of unknown function DUF104 1 57 9.7E-17 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_01440 c91bc0892e5493238e3c8cb55ac2816c 64 Gene3D G3DSA:4.10.1150.10 1 60 4.9E-14 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 Gene3D G3DSA:3.30.70.20 69 105 1.5E-9 T 23-10-2018 A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 Gene3D G3DSA:3.30.70.20 30 68 1.7E-5 T 23-10-2018 A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 9.1E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 SUPERFAMILY SSF54862 33 104 1.97E-24 T 23-10-2018 A3L14_10580 5829671706968ea3b39b11c3fafb015d 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 6.2E-11 T 23-10-2018 A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 4 168 1.4E-68 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 1.5E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 SUPERFAMILY SSF52374 3 166 5.04E-37 T 23-10-2018 A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 Gene3D G3DSA:3.40.50.620 1 178 4.3E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 Pfam PF01467 Cytidylyltransferase-like 6 136 1.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L14_08900 554efbc4247a4464d63ea847a78b1ec2 187 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 187 89.881 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L14_05780 90c72e257bcf98e8f240e3b429b23b1a 368 Pfam PF03222 Tryptophan/tyrosine permease family 7 363 7.0E-37 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L14_05780 90c72e257bcf98e8f240e3b429b23b1a 368 Gene3D G3DSA:1.20.1740.10 1 368 1.4E-15 T 23-10-2018 A3L14_01715 5df985c5ec164b560693ceb345f68805 98 Pfam PF11537 Protein of unknown function (DUF3227) 11 80 1.2E-15 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A3L14_01715 5df985c5ec164b560693ceb345f68805 98 Gene3D G3DSA:1.10.1200.200 6 98 2.0E-26 T 23-10-2018 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 PIRSF PIRSF000521 2 143 2.3E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 PIRSF PIRSF000521 128 447 1.1E-34 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 SUPERFAMILY SSF53383 34 445 3.42E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 Gene3D G3DSA:3.40.640.10 73 344 3.2E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 Pfam PF00202 Aminotransferase class-III 37 444 1.4E-98 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_00575 ca720e330fb82292e123f0ac2a9a7f30 460 Gene3D G3DSA:3.90.1150.10 19 440 3.2E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_07330 11be60828d90979b8406f7fbe6e0ce88 174 SUPERFAMILY SSF47240 14 165 1.11E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07330 11be60828d90979b8406f7fbe6e0ce88 174 Gene3D G3DSA:1.20.1260.10 12 161 1.8E-45 T 23-10-2018 IPR012347 Ferritin-like A3L14_07330 11be60828d90979b8406f7fbe6e0ce88 174 Pfam PF02915 Rubrerythrin 22 157 3.6E-31 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 184 195 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 SUPERFAMILY SSF52743 86 734 6.44E-61 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 Gene3D G3DSA:3.40.50.200 315 641 1.9E-66 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 378 388 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 374 387 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 179 198 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 571 587 5.1E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 572 582 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 Pfam PF00082 Subtilase family 179 624 4.3E-57 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L14_03100 a841d8b08a174bd793ab19596fb4f5ab 1424 Gene3D G3DSA:3.40.50.200 161 268 2.3E-8 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_00460 2836544895800c891253d8afbe1a6a3c 384 SUPERFAMILY SSF53383 2 373 1.14E-114 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_00460 2836544895800c891253d8afbe1a6a3c 384 PIRSF PIRSF000390 1 377 2.1E-115 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L14_00460 2836544895800c891253d8afbe1a6a3c 384 Gene3D G3DSA:3.90.1150.10 250 378 3.7E-33 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_00460 2836544895800c891253d8afbe1a6a3c 384 Gene3D G3DSA:3.40.640.10 1 249 2.0E-91 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_00460 2836544895800c891253d8afbe1a6a3c 384 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 369 2.1E-115 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 PIRSF PIRSF005303 1 308 9.4E-92 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 308 27.264 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 143 293 1.4E-11 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 Gene3D G3DSA:3.90.650.10 138 308 9.3E-47 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 SUPERFAMILY SSF55326 8 132 1.5E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 Gene3D G3DSA:3.30.1330.10 1 136 4.4E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 308 5.1E-84 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 23 132 5.4E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_04350 fd7f5a626591e37c05be4f0a0cb73378 321 SUPERFAMILY SSF56042 136 295 8.22E-41 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_00205 66dc10583ca738f22659e7524de8c305 191 Gene3D G3DSA:1.10.20.10 90 191 1.3E-51 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_00205 66dc10583ca738f22659e7524de8c305 191 Pfam PF12840 Helix-turn-helix domain 11 67 7.3E-15 T 23-10-2018 A3L14_00205 66dc10583ca738f22659e7524de8c305 191 SUPERFAMILY SSF46785 1 163 1.84E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00205 66dc10583ca738f22659e7524de8c305 191 SMART SM00418 11 105 2.3E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00205 66dc10583ca738f22659e7524de8c305 191 Gene3D G3DSA:1.10.10.10 1 89 4.9E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03720 e6c33125df94860591310a45df03f887 226 Gene3D G3DSA:3.40.30.10 1 117 5.3E-36 T 23-10-2018 A3L14_03720 e6c33125df94860591310a45df03f887 226 Gene3D G3DSA:3.40.30.10 121 225 4.0E-26 T 23-10-2018 A3L14_03720 e6c33125df94860591310a45df03f887 226 SUPERFAMILY SSF52833 5 116 1.56E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_03720 e6c33125df94860591310a45df03f887 226 SUPERFAMILY SSF52833 121 221 6.5E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_03720 e6c33125df94860591310a45df03f887 226 Pfam PF13192 Thioredoxin domain 137 222 1.5E-14 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L14_03720 e6c33125df94860591310a45df03f887 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 2.1E-85 T 23-10-2018 IPR011903 Glutaredoxin-like domain A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 Gene3D G3DSA:3.40.630.10 28 405 1.4E-55 T 23-10-2018 A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 Gene3D G3DSA:3.50.30.30 73 208 1.4E-55 T 23-10-2018 A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 SUPERFAMILY SSF52025 92 197 2.22E-6 T 23-10-2018 A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 Pfam PF04389 Peptidase family M28 228 412 2.2E-18 T 23-10-2018 IPR007484 Peptidase M28 A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 SUPERFAMILY SSF53187 9 420 7.11E-32 T 23-10-2018 A3L14_01625 b079e630cbfc2dc4a02a89a3b326eb48 562 Pfam PF02225 PA domain 122 185 4.6E-5 T 23-10-2018 IPR003137 PA domain A3L14_01790 d3d912ee8e21313165bad5e4c8a1b367 88 SUPERFAMILY SSF88723 20 82 1.05E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_01790 d3d912ee8e21313165bad5e4c8a1b367 88 Gene3D G3DSA:3.40.50.1010 24 87 3.9E-5 T 23-10-2018 A3L14_01790 d3d912ee8e21313165bad5e4c8a1b367 88 Pfam PF01850 PIN domain 9 83 2.4E-12 T 23-10-2018 IPR002716 PIN domain A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 3.5E-81 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 Gene3D G3DSA:3.30.2130.30 1 149 7.6E-24 T 23-10-2018 A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 SUPERFAMILY SSF143437 3 147 4.88E-27 T 23-10-2018 A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 SMART SM00981 60 149 1.8E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 SUPERFAMILY SSF75217 187 336 2.22E-20 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_05035 53e61d4b1f7cdf8d48b622c5ed3f2f93 351 Pfam PF02926 THUMP domain 36 149 8.7E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 Gene3D G3DSA:3.20.20.70 63 286 2.0E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 PIRSF PIRSF004869 1 313 3.3E-96 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 Pfam PF13353 4Fe-4S single cluster domain 75 173 3.8E-7 T 23-10-2018 A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 Pfam PF04055 Radical SAM superfamily 78 234 2.8E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 345 7.0E-111 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A3L14_04330 5a06aba7939f0a3ad9876a26307400aa 348 SUPERFAMILY SSF102114 58 315 6.54E-35 T 23-10-2018 A3L14_08245 9a99652f1d2507b6d7bf74cee8be74e0 299 Gene3D G3DSA:3.40.1360.10 4 119 3.2E-6 T 23-10-2018 A3L14_08245 9a99652f1d2507b6d7bf74cee8be74e0 299 Pfam PF01751 Toprim domain 8 87 6.8E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L14_08245 9a99652f1d2507b6d7bf74cee8be74e0 299 SMART SM00493 5 84 9.0E-7 T 23-10-2018 IPR006171 TOPRIM domain A3L14_01835 4981880f5755d7a08e28f36acc9f54ca 56 Pfam PF03911 Sec61beta family 11 51 1.6E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_01835 4981880f5755d7a08e28f36acc9f54ca 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 15.167 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A3L14_10505 9b3330257e74f1ecd6c825653f7956f8 430 SUPERFAMILY SSF52540 31 234 3.23E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10505 9b3330257e74f1ecd6c825653f7956f8 430 Pfam PF13635 Domain of unknown function (DUF4143) 217 362 3.1E-15 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L14_10505 9b3330257e74f1ecd6c825653f7956f8 430 Pfam PF13173 AAA domain 43 160 4.7E-25 T 23-10-2018 A3L14_10065 0d61f499efe4a47596572dbae059938b 188 PIRSF PIRSF006503 1 188 1.3E-84 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L14_10065 0d61f499efe4a47596572dbae059938b 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 5.0E-91 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L14_10065 0d61f499efe4a47596572dbae059938b 188 Gene3D G3DSA:3.30.930.10 1 188 1.1E-71 T 23-10-2018 A3L14_10065 0d61f499efe4a47596572dbae059938b 188 SUPERFAMILY SSF55681 3 186 1.24E-71 T 23-10-2018 A3L14_10065 0d61f499efe4a47596572dbae059938b 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 3.9E-68 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L14_03585 026eaa81fb153aee900613fc1a96410c 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 1.9E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L14_03585 026eaa81fb153aee900613fc1a96410c 67 Gene3D G3DSA:1.10.20.10 1 67 4.3E-24 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_03585 026eaa81fb153aee900613fc1a96410c 67 SUPERFAMILY SSF47113 3 66 1.16E-19 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_08080 443c8a9fa3fad2a57957c6a586d4daeb 210 SUPERFAMILY SSF50475 6 187 3.01E-31 T 23-10-2018 A3L14_08080 443c8a9fa3fad2a57957c6a586d4daeb 210 PIRSF PIRSF018747 1 195 5.5E-42 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A3L14_08080 443c8a9fa3fad2a57957c6a586d4daeb 210 Gene3D G3DSA:1.20.58.290 60 165 3.1E-10 T 23-10-2018 A3L14_08080 443c8a9fa3fad2a57957c6a586d4daeb 210 Pfam PF04289 Protein of unknown function (DUF447) 13 184 1.7E-23 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A3L14_08080 443c8a9fa3fad2a57957c6a586d4daeb 210 Gene3D G3DSA:2.30.110.10 12 130 3.1E-10 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L14_04595 86a70ef0f9a3328c4ab4bb3a3bc74d08 327 Gene3D G3DSA:3.90.1640.10 8 192 8.1E-37 T 23-10-2018 A3L14_04595 86a70ef0f9a3328c4ab4bb3a3bc74d08 327 Gene3D G3DSA:3.10.310.40 221 321 7.0E-7 T 23-10-2018 A3L14_04595 86a70ef0f9a3328c4ab4bb3a3bc74d08 327 SUPERFAMILY SSF64182 17 306 9.42E-49 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L14_04595 86a70ef0f9a3328c4ab4bb3a3bc74d08 327 Pfam PF01368 DHH family 19 159 1.0E-11 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L14_04595 86a70ef0f9a3328c4ab4bb3a3bc74d08 327 Pfam PF02272 DHHA1 domain 240 317 1.4E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L14_09770 7ae0db547b358a7010dadad6bc89120a 177 SUPERFAMILY SSF56399 5 175 1.73E-54 T 23-10-2018 A3L14_09770 7ae0db547b358a7010dadad6bc89120a 177 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 3 175 33.129 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A3L14_09770 7ae0db547b358a7010dadad6bc89120a 177 Gene3D G3DSA:1.10.10.970 3 74 9.2E-21 T 23-10-2018 A3L14_09770 7ae0db547b358a7010dadad6bc89120a 177 Gene3D G3DSA:3.20.170.30 94 177 1.1E-29 T 23-10-2018 A3L14_09770 7ae0db547b358a7010dadad6bc89120a 177 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 4 165 2.6E-31 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 SUPERFAMILY SSF55326 6 147 3.66E-22 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 305 1.2E-17 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 Gene3D G3DSA:3.30.1330.10 16 147 1.3E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 143 8.2E-15 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 Gene3D G3DSA:3.90.650.10 152 328 8.5E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 PIRSF PIRSF005644 1 329 3.0E-65 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L14_05895 6cdb4d9125aa48ce6139b18feae42e97 332 SUPERFAMILY SSF56042 152 314 7.03E-29 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_00695 c531e0d5e66e0ff0d75fd8df081bcc7d 103 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 6 79 1.8E-6 T 23-10-2018 A3L14_00695 c531e0d5e66e0ff0d75fd8df081bcc7d 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 1.1E-17 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A3L14_00695 c531e0d5e66e0ff0d75fd8df081bcc7d 103 Gene3D G3DSA:1.20.5.620 30 91 2.0E-5 T 23-10-2018 A3L14_00695 c531e0d5e66e0ff0d75fd8df081bcc7d 103 SUPERFAMILY SSF81573 35 88 9.94E-7 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Gene3D G3DSA:3.30.460.10 16 152 7.8E-85 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 SUPERFAMILY SSF81301 1 150 7.85E-35 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 SUPERFAMILY SSF55003 265 449 9.81E-40 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 419 6.5E-140 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 PIRSF PIRSF005335 1 454 5.4E-150 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 278 4.3E-38 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Gene3D G3DSA:3.30.70.1550 360 399 2.4E-25 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 SUPERFAMILY SSF81631 153 279 3.14E-37 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Gene3D G3DSA:1.10.1410.30 9 278 7.8E-85 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Pfam PF01909 Nucleotidyltransferase domain 36 141 4.9E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Gene3D G3DSA:3.30.70.590 291 427 2.4E-25 T 23-10-2018 A3L14_01025 5cd78f179b1bd343d01b02269c651eec 455 Hamap MF_01264 CCA-adding enzyme [cca]. 1 455 159.332 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L14_05465 c37d799745eb368ff8f4dcb2c28e0eab 248 Pfam PF07786 Protein of unknown function (DUF1624) 11 230 1.4E-59 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 Gene3D G3DSA:1.10.287.310 1 66 1.4E-19 T 23-10-2018 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 SUPERFAMILY SSF46561 1 61 2.88E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.837 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 2.8E-20 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02510 38876fae3cac4630ad5b1546b3f91b8e 66 Pfam PF00831 Ribosomal L29 protein 4 61 1.1E-17 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03160 1ff049db669a771205ecfadf59053aa7 108 Gene3D G3DSA:3.30.460.10 2 103 6.9E-19 T 23-10-2018 A3L14_03160 1ff049db669a771205ecfadf59053aa7 108 SUPERFAMILY SSF81301 2 108 1.45E-21 T 23-10-2018 A3L14_03160 1ff049db669a771205ecfadf59053aa7 108 Pfam PF01909 Nucleotidyltransferase domain 11 79 1.3E-13 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 SUPERFAMILY SSF52540 3 236 5.0E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 SMART SM00382 3 163 0.0036 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 Gene3D G3DSA:3.40.50.300 4 233 1.8E-66 T 23-10-2018 A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 PIRSF PIRSF003092 1 259 1.5E-65 T 23-10-2018 IPR025501 ATP binding protein MinD A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.8E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L14_08425 0487bd1b6f27c1c53b83be6d96d94e07 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 3.6E-24 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_08175 1afa3e31d865f8f49e6736b3be2e4070 227 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 14 210 1.0E-38 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_08175 1afa3e31d865f8f49e6736b3be2e4070 227 Gene3D G3DSA:3.40.50.11570 9 214 7.7E-49 T 23-10-2018 A3L14_04965 5a2e30248dcdc42a012ea3281640324f 185 SUPERFAMILY SSF48371 29 158 1.92E-14 T 23-10-2018 IPR016024 Armadillo-type fold A3L14_04965 5a2e30248dcdc42a012ea3281640324f 185 Gene3D G3DSA:1.25.10.10 24 167 5.7E-10 T 23-10-2018 IPR011989 Armadillo-like helical A3L14_00945 642dd434226fbfb5555399e703fa02e2 299 Gene3D G3DSA:1.10.3720.10 54 296 1.1E-56 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00945 642dd434226fbfb5555399e703fa02e2 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 284 1.8E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00945 642dd434226fbfb5555399e703fa02e2 299 SUPERFAMILY SSF160964 7 42 1.26E-6 T 23-10-2018 A3L14_00945 642dd434226fbfb5555399e703fa02e2 299 SUPERFAMILY SSF161098 58 284 9.55E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08375 8f0801cbf9c13972fdb663e513cad42e 164 Gene3D G3DSA:3.40.50.1010 1 118 2.3E-42 T 23-10-2018 A3L14_08375 8f0801cbf9c13972fdb663e513cad42e 164 Pfam PF17146 PIN domain of ribonuclease 5 87 5.5E-19 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A3L14_08375 8f0801cbf9c13972fdb663e513cad42e 164 SUPERFAMILY SSF88723 20 114 1.08E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08375 8f0801cbf9c13972fdb663e513cad42e 164 Gene3D G3DSA:2.20.28.10 119 157 4.3E-20 T 23-10-2018 A3L14_08375 8f0801cbf9c13972fdb663e513cad42e 164 SMART SM00670 2 100 0.004 T 23-10-2018 IPR002716 PIN domain A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Gene3D G3DSA:3.40.50.200 132 439 1.2E-133 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 PIRSF PIRSF037907 1 657 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 200 210 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 SUPERFAMILY SSF52743 142 437 6.68E-95 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Gene3D G3DSA:2.60.120.380 557 655 3.1E-14 T 23-10-2018 A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Gene3D G3DSA:2.60.120.380 440 540 1.4E-21 T 23-10-2018 A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 163 174 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 572 639 7.5E-6 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 177 4.7E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 375 391 4.7E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 196 209 4.7E-24 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 376 386 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Pfam PF00082 Subtilase family 158 427 1.2E-67 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 SUPERFAMILY SSF49785 448 523 7.06E-6 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A3L14_09880 4b972453e0dacea1c2dccc8abfaf6190 657 Gene3D G3DSA:3.30.70.80 40 131 2.6E-41 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A3L14_03300 1ffd44377183d768a93a9a0b1f1d125e 59 Gene3D G3DSA:2.20.28.40 1 59 4.0E-30 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L14_03300 1ffd44377183d768a93a9a0b1f1d125e 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 2.8E-27 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L14_03300 1ffd44377183d768a93a9a0b1f1d125e 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.144 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A3L14_03300 1ffd44377183d768a93a9a0b1f1d125e 59 SUPERFAMILY SSF144210 4 51 1.96E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L14_10665 f2b758a1e0fb264d8acae49dbd6b0ed9 103 SUPERFAMILY SSF54913 3 100 3.67E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L14_10665 f2b758a1e0fb264d8acae49dbd6b0ed9 103 Pfam PF03091 CutA1 divalent ion tolerance protein 5 100 2.6E-32 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A3L14_10665 f2b758a1e0fb264d8acae49dbd6b0ed9 103 Gene3D G3DSA:3.30.70.120 1 102 7.8E-38 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L14_01380 738c49badd7acb570e108c12d669ee38 334 Gene3D G3DSA:3.90.650.10 166 332 1.6E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01380 738c49badd7acb570e108c12d669ee38 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 8.6E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_01380 738c49badd7acb570e108c12d669ee38 334 SUPERFAMILY SSF56042 167 327 1.26E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_01380 738c49badd7acb570e108c12d669ee38 334 Gene3D G3DSA:3.30.1330.10 2 165 6.7E-51 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_01380 738c49badd7acb570e108c12d669ee38 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.381 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01380 738c49badd7acb570e108c12d669ee38 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 1.4E-121 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L14_01380 738c49badd7acb570e108c12d669ee38 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 327 2.3E-25 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_01380 738c49badd7acb570e108c12d669ee38 334 SUPERFAMILY SSF55326 2 165 1.26E-39 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_08755 21986578b29378b02bcd732911ca3464 244 Gene3D G3DSA:3.20.20.20 159 220 1.3E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_08755 21986578b29378b02bcd732911ca3464 244 Pfam PF04060 Putative Fe-S cluster 160 191 1.1E-8 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A3L14_08755 21986578b29378b02bcd732911ca3464 244 SUPERFAMILY SSF52540 1 109 4.39E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08755 21986578b29378b02bcd732911ca3464 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 112 6.4E-17 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L14_08755 21986578b29378b02bcd732911ca3464 244 Gene3D G3DSA:3.40.50.300 2 158 4.6E-27 T 23-10-2018 A3L14_08685 17bac603e261f961e241a41e4a4f8e17 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 43 8.1E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_08685 17bac603e261f961e241a41e4a4f8e17 82 Gene3D G3DSA:2.10.260.10 3 40 1.4E-13 T 23-10-2018 A3L14_08685 17bac603e261f961e241a41e4a4f8e17 82 SMART SM00966 2 47 7.7E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_08685 17bac603e261f961e241a41e4a4f8e17 82 SUPERFAMILY SSF89447 4 61 1.92E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_08685 17bac603e261f961e241a41e4a4f8e17 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 40 3.4E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_10250 3fccea04fca500db69a5d1daa0cc6ba6 379 Gene3D G3DSA:3.40.50.1100 91 186 1.1E-103 T 23-10-2018 A3L14_10250 3fccea04fca500db69a5d1daa0cc6ba6 379 Gene3D G3DSA:3.40.50.1100 43 354 1.1E-103 T 23-10-2018 A3L14_10250 3fccea04fca500db69a5d1daa0cc6ba6 379 TIGRFAM TIGR00260 thrC: threonine synthase 50 354 2.6E-53 T 23-10-2018 IPR004450 Threonine synthase-like A3L14_10250 3fccea04fca500db69a5d1daa0cc6ba6 379 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 349 3.8E-69 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_10250 3fccea04fca500db69a5d1daa0cc6ba6 379 SUPERFAMILY SSF53686 4 356 9.43E-86 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_06295 f739f390ff9aad15ee43a0eabf91fc5a 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 3.0E-41 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L14_06295 f739f390ff9aad15ee43a0eabf91fc5a 142 SUPERFAMILY SSF69819 2 142 1.83E-47 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L14_06295 f739f390ff9aad15ee43a0eabf91fc5a 142 Gene3D G3DSA:3.55.10.10 1 142 1.5E-51 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L14_06295 f739f390ff9aad15ee43a0eabf91fc5a 142 Hamap MF_01222 Protein archease. 2 142 41.027 T 23-10-2018 IPR022952 Archease, archaea A3L14_06295 f739f390ff9aad15ee43a0eabf91fc5a 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 2.4E-44 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L14_01515 1cda8984bf2a03d9212be82b0761ef95 195 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 189 2.0E-62 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A3L14_01515 1cda8984bf2a03d9212be82b0761ef95 195 SUPERFAMILY SSF53335 4 180 4.74E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_01515 1cda8984bf2a03d9212be82b0761ef95 195 Pfam PF13847 Methyltransferase domain 34 164 3.6E-18 T 23-10-2018 IPR025714 Methyltransferase domain A3L14_01515 1cda8984bf2a03d9212be82b0761ef95 195 Gene3D G3DSA:3.40.50.150 13 193 4.1E-40 T 23-10-2018 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 Pfam PF00654 Voltage gated chloride channel 69 411 3.0E-85 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 PRINTS PR00762 Chloride channel signature 326 346 1.3E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 PRINTS PR00762 Chloride channel signature 81 98 1.3E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 PRINTS PR00762 Chloride channel signature 161 180 1.3E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 PRINTS PR00762 Chloride channel signature 361 377 1.3E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 Gene3D G3DSA:1.10.3080.10 2 431 1.4E-95 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 Gene3D G3DSA:3.10.580.10 437 564 7.0E-24 T 23-10-2018 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 SUPERFAMILY SSF54631 437 563 6.95E-27 T 23-10-2018 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 SUPERFAMILY SSF81340 8 432 1.44E-99 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 Pfam PF00571 CBS domain 444 497 1.1E-12 T 23-10-2018 IPR000644 CBS domain A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 Pfam PF00571 CBS domain 506 561 9.3E-7 T 23-10-2018 IPR000644 CBS domain A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 SMART SM00116 451 499 2.1E-7 T 23-10-2018 IPR000644 CBS domain A3L14_04365 46b7c35bfcc83633b18249f9b7e0c57e 572 SMART SM00116 513 563 0.053 T 23-10-2018 IPR000644 CBS domain A3L14_06920 cd780ad060841a71c051ed725e131477 636 SUPERFAMILY SSF53706 4 519 1.96E-136 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Gene3D G3DSA:3.30.2070.10 407 487 7.0E-117 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Pfam PF00384 Molybdopterin oxidoreductase 56 423 3.3E-46 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_06920 cd780ad060841a71c051ed725e131477 636 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A3L14_06920 cd780ad060841a71c051ed725e131477 636 SMART SM00926 1 53 3.0E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_06920 cd780ad060841a71c051ed725e131477 636 SUPERFAMILY SSF50692 515 635 1.29E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L14_06920 cd780ad060841a71c051ed725e131477 636 Pfam PF01568 Molydopterin dinucleotide binding domain 537 629 9.6E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Gene3D G3DSA:3.40.228.10 133 505 7.0E-117 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Gene3D G3DSA:2.40.40.20 509 636 4.3E-28 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Gene3D G3DSA:3.40.50.740 67 450 7.0E-117 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Gene3D G3DSA:2.20.25.90 2 58 1.8E-11 T 23-10-2018 A3L14_06920 cd780ad060841a71c051ed725e131477 636 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 2.1E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_03605 b5ff843ac5c480fab0c01fa33f457a4e 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 4.3E-42 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A3L14_03605 b5ff843ac5c480fab0c01fa33f457a4e 105 Pfam PF00428 60s Acidic ribosomal protein 16 104 1.3E-19 T 23-10-2018 A3L14_03605 b5ff843ac5c480fab0c01fa33f457a4e 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 14.692 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03605 b5ff843ac5c480fab0c01fa33f457a4e 105 Gene3D G3DSA:1.10.10.1410 1 58 4.4E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 48.19 T 23-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 SUPERFAMILY SSF53850 1 201 7.78E-61 T 23-10-2018 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 177 1.1E-59 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 Gene3D G3DSA:3.40.190.10 3 193 4.7E-64 T 23-10-2018 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 Gene3D G3DSA:3.40.190.10 86 170 4.7E-64 T 23-10-2018 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A3L14_07420 87a00faca66baa7d28352a1da4e8725f 205 Pfam PF01634 ATP phosphoribosyltransferase 46 198 1.2E-48 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 6.6E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 Pfam PF12800 4Fe-4S binding domain 97 111 0.0029 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 SUPERFAMILY SSF52540 3 283 6.32E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 Gene3D G3DSA:3.30.70.20 63 115 2.4E-9 T 23-10-2018 A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 Pfam PF00037 4Fe-4S binding domain 63 84 2.7E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07590 b8dbd2ec48c65ee2677469a58e17a808 289 SUPERFAMILY SSF54862 51 120 3.31E-17 T 23-10-2018 A3L14_07680 de72aa076e07a4aed36da9b69588c7c1 138 Pfam PF01850 PIN domain 5 130 2.4E-13 T 23-10-2018 IPR002716 PIN domain A3L14_07680 de72aa076e07a4aed36da9b69588c7c1 138 SUPERFAMILY SSF88723 5 137 8.83E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_07680 de72aa076e07a4aed36da9b69588c7c1 138 Gene3D G3DSA:3.40.50.1010 4 133 4.8E-9 T 23-10-2018 A3L14_04320 46e97da1fd20c438a2b93b25eb9a1727 607 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 604 8.6E-61 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L14_04320 46e97da1fd20c438a2b93b25eb9a1727 607 Pfam PF05123 S-layer like family, N-terminal region 4 309 1.1E-42 T 23-10-2018 IPR022650 S-layer protein, N-terminal A3L14_04320 46e97da1fd20c438a2b93b25eb9a1727 607 Pfam PF05124 S-layer like family, C-terminal region 373 604 2.0E-30 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L14_05070 2f0b13cd80bdffdbf2bbafed8372ee7f 266 Pfam PF10869 Protein of unknown function (DUF2666) 4 116 1.7E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L14_05070 2f0b13cd80bdffdbf2bbafed8372ee7f 266 Pfam PF10869 Protein of unknown function (DUF2666) 138 265 1.1E-37 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L14_05070 2f0b13cd80bdffdbf2bbafed8372ee7f 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 103 4.0E-26 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L14_05070 2f0b13cd80bdffdbf2bbafed8372ee7f 266 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 265 2.0E-41 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L14_01155 1826bc9e133d3cc1e4f508c08fe3d195 204 SUPERFAMILY SSF46785 7 150 2.23E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_01155 1826bc9e133d3cc1e4f508c08fe3d195 204 Gene3D G3DSA:1.10.10.10 5 64 8.8E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_11305 a762e4fcb9577de274edbfa0e9a272c4 167 PIRSF PIRSF019239 3 166 1.5E-36 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_11305 a762e4fcb9577de274edbfa0e9a272c4 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 165 6.6E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_11285 edc6259fc9d4cdea6029acfd5c5a556d 174 SUPERFAMILY SSF143243 9 160 3.14E-32 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11285 edc6259fc9d4cdea6029acfd5c5a556d 174 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 35 151 2.2E-23 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11285 edc6259fc9d4cdea6029acfd5c5a556d 174 Gene3D G3DSA:3.30.460.80 13 134 5.8E-19 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11285 edc6259fc9d4cdea6029acfd5c5a556d 174 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 151 8.0E-15 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_06990 c973e5d0c79c2de0d4857360dfdc7a49 390 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 358 2.3E-64 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L14_06990 c973e5d0c79c2de0d4857360dfdc7a49 390 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 42 60 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A3L14_06990 c973e5d0c79c2de0d4857360dfdc7a49 390 SUPERFAMILY SSF53686 10 378 4.08E-91 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_00295 5eafac8871d4414de9f1c33687e83b95 619 Gene3D G3DSA:3.30.450.380 102 319 3.8E-66 T 23-10-2018 A3L14_00295 5eafac8871d4414de9f1c33687e83b95 619 SMART SM00382 352 517 0.0016 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00295 5eafac8871d4414de9f1c33687e83b95 619 Pfam PF00437 Type II/IV secretion system protein 225 482 4.9E-64 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L14_00295 5eafac8871d4414de9f1c33687e83b95 619 Gene3D G3DSA:3.40.50.300 320 607 2.6E-101 T 23-10-2018 A3L14_00295 5eafac8871d4414de9f1c33687e83b95 619 SUPERFAMILY SSF52540 205 518 7.61E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 PRINTS PR00423 Cell division protein FtsZ signature 156 177 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 PRINTS PR00423 Cell division protein FtsZ signature 218 240 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 PRINTS PR00423 Cell division protein FtsZ signature 128 148 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 PRINTS PR00423 Cell division protein FtsZ signature 241 262 7.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 Gene3D G3DSA:3.40.50.1440 35 249 4.9E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 Gene3D G3DSA:3.30.1330.20 254 364 2.9E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 SUPERFAMILY SSF52490 42 237 8.5E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 SMART SM00865 236 352 1.2E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 Pfam PF12327 FtsZ family, C-terminal domain 251 343 6.8E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 SMART SM00864 43 234 1.5E-106 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 355 1.2E-135 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 3.7E-46 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 SUPERFAMILY SSF55307 236 348 2.29E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L14_03635 aa3a139b80cd0db394cfab468ebad555 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 373 38.225 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 Pfam PF07687 Peptidase dimerisation domain 206 317 6.1E-19 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 414 3.2E-78 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 Gene3D G3DSA:3.40.630.10 9 211 1.5E-45 T 23-10-2018 A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 Gene3D G3DSA:3.40.630.10 314 421 2.1E-12 T 23-10-2018 A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 SUPERFAMILY SSF53187 7 419 8.3E-64 T 23-10-2018 A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 Gene3D G3DSA:3.30.70.360 212 313 3.5E-16 T 23-10-2018 A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 SUPERFAMILY SSF55031 211 322 1.21E-17 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L14_00900 762df30dd59163d523f38f68dd211ebc 421 Pfam PF01546 Peptidase family M20/M25/M40 96 419 1.9E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 4.7E-83 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 8.0E-87 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 Gene3D G3DSA:3.40.1180.10 19 264 1.1E-102 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.272 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L14_04035 e88e6881c108081c43fc1397cf698d96 264 SUPERFAMILY SSF64005 31 259 5.49E-88 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 SUPERFAMILY SSF51735 2 211 2.85E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 Pfam PF00106 short chain dehydrogenase 3 184 1.1E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_02625 800e44d37805f9a0a7375ee71a77057c 236 Gene3D G3DSA:3.40.50.720 1 234 1.3E-53 T 23-10-2018 A3L14_06975 5df0b1a53dba4043040ce9a0993be871 217 Gene3D G3DSA:3.40.50.150 6 204 2.7E-40 T 23-10-2018 A3L14_06975 5df0b1a53dba4043040ce9a0993be871 217 Pfam PF08241 Methyltransferase domain 45 140 8.1E-24 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L14_06975 5df0b1a53dba4043040ce9a0993be871 217 SUPERFAMILY SSF53335 8 197 6.97E-42 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_00915 59f8d739a318f0551f14c53a44821c08 271 Gene3D G3DSA:3.60.15.10 1 253 3.3E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_00915 59f8d739a318f0551f14c53a44821c08 271 SUPERFAMILY SSF56281 3 251 5.86E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_00915 59f8d739a318f0551f14c53a44821c08 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 1.0E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_10130 3e8652bfcd225ae55b02745fb51c349d 74 SUPERFAMILY SSF89447 2 44 1.33E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_10130 3e8652bfcd225ae55b02745fb51c349d 74 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 45 5.0E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_10130 3e8652bfcd225ae55b02745fb51c349d 74 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 44 1.2E-14 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_10130 3e8652bfcd225ae55b02745fb51c349d 74 Gene3D G3DSA:2.10.260.10 2 42 1.5E-14 T 23-10-2018 A3L14_10130 3e8652bfcd225ae55b02745fb51c349d 74 SMART SM00966 4 47 2.4E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_04620 165d160b9129d9f5895bef30e5ce690a 306 Gene3D G3DSA:1.10.3720.10 61 303 2.1E-26 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04620 165d160b9129d9f5895bef30e5ce690a 306 SUPERFAMILY SSF161098 12 292 1.64E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04620 165d160b9129d9f5895bef30e5ce690a 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 292 1.5E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_04620 165d160b9129d9f5895bef30e5ce690a 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 7 299 8.4E-89 T 23-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A3L14_02370 8d9a3424cb3f5502f64fda7104e74c42 230 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 212 2.3E-61 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_02370 8d9a3424cb3f5502f64fda7104e74c42 230 Gene3D G3DSA:3.40.50.11570 4 216 3.1E-56 T 23-10-2018 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 2.2E-43 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.131 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 1.3E-37 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 Gene3D G3DSA:3.30.160.750 66 129 1.0E-24 T 23-10-2018 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 SUPERFAMILY SSF56276 6 120 1.7E-41 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A3L14_00675 79cc32b940f00cdcbaf0a9957d306992 143 Gene3D G3DSA:3.30.360.110 4 65 4.0E-18 T 23-10-2018 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Gene3D G3DSA:2.10.240.10 250 287 9.5E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 SUPERFAMILY SSF63380 18 115 1.97E-23 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 218 226 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 145 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Gene3D G3DSA:3.40.50.80 115 248 7.5E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Pfam PF00175 Oxidoreductase NAD-binding domain 127 231 3.8E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 PIRSF PIRSF006816 16 293 3.5E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 SUPERFAMILY SSF52343 110 285 1.57E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 250 286 9.1E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Gene3D G3DSA:2.40.30.10 16 114 2.1E-19 T 23-10-2018 A3L14_05110 09bfc2f223860addd1d507e8b67c2928 294 Pfam PF00970 Oxidoreductase FAD-binding domain 36 113 8.9E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L14_03820 14058ed30d0c7535269711bc797f49ad 70 SUPERFAMILY SSF46785 5 60 1.16E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03820 14058ed30d0c7535269711bc797f49ad 70 Gene3D G3DSA:1.10.10.10 2 70 1.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_08690 a99e983ed26d8ad540245de720f159ab 201 Gene3D G3DSA:3.40.50.620 2 200 6.6E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_08690 a99e983ed26d8ad540245de720f159ab 201 Pfam PF00733 Asparagine synthase 8 68 2.6E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L14_08690 a99e983ed26d8ad540245de720f159ab 201 SUPERFAMILY SSF52402 6 152 1.76E-22 T 23-10-2018 A3L14_03590 4a74afb8e3ade9bf5d663074fc01f7af 156 SUPERFAMILY SSF51283 1 153 1.57E-38 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L14_03590 4a74afb8e3ade9bf5d663074fc01f7af 156 Gene3D G3DSA:2.70.40.10 1 156 1.4E-41 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L14_03590 4a74afb8e3ade9bf5d663074fc01f7af 156 Pfam PF00692 dUTPase 43 139 1.6E-12 T 23-10-2018 IPR029054 dUTPase-like A3L14_03590 4a74afb8e3ade9bf5d663074fc01f7af 156 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.488 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L14_03590 4a74afb8e3ade9bf5d663074fc01f7af 156 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 8 152 2.6E-45 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 Pfam PF00297 Ribosomal protein L3 3 347 2.3E-90 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 Gene3D G3DSA:2.40.30.10 39 327 2.6E-123 T 23-10-2018 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 Gene3D G3DSA:3.30.1430.10 77 188 2.6E-123 T 23-10-2018 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 SUPERFAMILY SSF50447 3 347 4.24E-96 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 Gene3D G3DSA:4.10.960.10 6 257 2.6E-123 T 23-10-2018 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.494 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02475 9f8dc685f08286b142d6fec969279e32 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 2.9E-136 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07915 aee4447495acfdde0add875d114ff56b 167 Gene3D G3DSA:1.20.5.340 22 147 4.7E-7 T 23-10-2018 A3L14_07915 aee4447495acfdde0add875d114ff56b 167 Pfam PF05377 Flagella accessory protein C (FlaC) 57 110 6.9E-20 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A3L14_10100 e4a370eeb607540d410f077b15960dea 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 3 276 4.1E-89 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 SUPERFAMILY SSF53271 62 270 9.99E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_10100 e4a370eeb607540d410f077b15960dea 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 18 109 2.2E-19 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 Pfam PF00156 Phosphoribosyl transferase domain 143 242 4.5E-19 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 Gene3D G3DSA:3.40.50.2020 23 138 7.6E-82 T 23-10-2018 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 36.149 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 SMART SM01400 1 113 2.9E-30 T 23-10-2018 A3L14_10100 e4a370eeb607540d410f077b15960dea 279 Gene3D G3DSA:3.40.50.2020 139 263 7.6E-82 T 23-10-2018 A3L14_07720 3ca023cf566de7cb38693304330c4793 449 Pfam PF01637 ATPase domain predominantly from Archaea 5 202 4.6E-28 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_07720 3ca023cf566de7cb38693304330c4793 449 Pfam PF03008 Archaea bacterial proteins of unknown function 310 391 5.3E-22 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_07720 3ca023cf566de7cb38693304330c4793 449 Gene3D G3DSA:3.40.50.300 1 168 3.8E-30 T 23-10-2018 A3L14_07720 3ca023cf566de7cb38693304330c4793 449 SUPERFAMILY SSF52980 344 392 7.24E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_07720 3ca023cf566de7cb38693304330c4793 449 SUPERFAMILY SSF52540 4 242 5.45E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07720 3ca023cf566de7cb38693304330c4793 449 SUPERFAMILY SSF46785 243 320 5.73E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05065 991e7496be8a0bf1ec007e16da909242 127 SUPERFAMILY SSF55298 1 127 1.13E-44 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L14_05065 991e7496be8a0bf1ec007e16da909242 127 Pfam PF01042 Endoribonuclease L-PSP 9 126 8.1E-43 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A3L14_05065 991e7496be8a0bf1ec007e16da909242 127 Gene3D G3DSA:3.30.1330.40 1 127 5.3E-51 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L14_05065 991e7496be8a0bf1ec007e16da909242 127 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 A3L14_05065 991e7496be8a0bf1ec007e16da909242 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 2.6E-50 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 Gene3D G3DSA:3.30.420.80 3 139 5.2E-65 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 15 131 7.0E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 Pfam PF00411 Ribosomal protein S11 17 135 2.1E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 SUPERFAMILY SSF53137 11 137 3.47E-39 T 23-10-2018 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 PIRSF PIRSF002131 1 138 2.4E-35 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L14_02665 814d4b4748449f1ca5c6b3f9fdb56a26 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 136 23.642 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L14_06270 cca894341e3812edcb230dec69e4a7ce 708 Gene3D G3DSA:2.60.40.1120 381 453 2.7E-7 T 23-10-2018 A3L14_06270 cca894341e3812edcb230dec69e4a7ce 708 SUPERFAMILY SSF49464 385 467 2.35E-6 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily A3L14_06270 cca894341e3812edcb230dec69e4a7ce 708 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 594 663 4.5E-7 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A3L14_01030 2d169d7af65cedc9522fd3cd6e7cb28d 439 Pfam PF13173 AAA domain 43 165 6.6E-21 T 23-10-2018 A3L14_01030 2d169d7af65cedc9522fd3cd6e7cb28d 439 SUPERFAMILY SSF52540 12 238 1.72E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06150 c442eb19592e217fbdf5fb15c43a339a 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.552 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A3L14_06150 c442eb19592e217fbdf5fb15c43a339a 318 SMART SM00530 130 185 2.0E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_06150 c442eb19592e217fbdf5fb15c43a339a 318 Pfam PF01381 Helix-turn-helix 131 184 2.7E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_06150 c442eb19592e217fbdf5fb15c43a339a 318 Gene3D G3DSA:1.10.260.40 129 187 2.8E-12 T 23-10-2018 A3L14_06150 c442eb19592e217fbdf5fb15c43a339a 318 SUPERFAMILY SSF47413 126 185 7.68E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 SUPERFAMILY SSF54909 61 129 6.97E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.8E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.8E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.8E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 Gene3D G3DSA:3.30.70.920 57 137 2.5E-6 T 23-10-2018 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 SMART SM00344 1 106 3.5E-13 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 45 2.1E-11 T 23-10-2018 A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 SUPERFAMILY SSF46785 1 66 9.93E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 Pfam PF01037 Lrp/AsnC ligand binding domain 67 132 4.6E-6 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_07155 56228dd0b0d435c74299cd85133b52f1 209 Gene3D G3DSA:1.10.10.10 1 48 2.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 Gene3D G3DSA:3.40.50.300 339 527 1.6E-21 T 23-10-2018 A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 Pfam PF00488 MutS domain V 389 471 4.2E-7 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 SMART SM00534 386 574 4.2E-27 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 PIRSF PIRSF029254 1 575 5.0E-194 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 SUPERFAMILY SSF52540 382 551 1.67E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06250 ac4b0aa07583edcd866548ad34aa28ab 575 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.583 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L14_03510 d5878cb2645d584b268fe3b51de2a8cb 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 110 4.4E-30 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L14_03510 d5878cb2645d584b268fe3b51de2a8cb 248 SUPERFAMILY SSF51695 7 241 7.33E-58 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L14_03510 d5878cb2645d584b268fe3b51de2a8cb 248 Gene3D G3DSA:3.20.20.190 1 248 6.7E-97 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L14_02375 10deedfd5e4c70922fde56360e091d9b 415 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 402 411 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L14_02375 10deedfd5e4c70922fde56360e091d9b 415 Pfam PF00374 Nickel-dependent hydrogenase 39 121 2.3E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_02375 10deedfd5e4c70922fde56360e091d9b 415 Pfam PF00374 Nickel-dependent hydrogenase 226 411 1.9E-16 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_02375 10deedfd5e4c70922fde56360e091d9b 415 Gene3D G3DSA:1.10.645.10 1 411 2.3E-97 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02375 10deedfd5e4c70922fde56360e091d9b 415 SUPERFAMILY SSF56762 2 411 2.62E-91 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_07335 b5f47792f96aa3d52d965a3025f8dbe1 147 Gene3D G3DSA:1.20.1260.10 1 144 6.6E-8 T 23-10-2018 IPR012347 Ferritin-like A3L14_07335 b5f47792f96aa3d52d965a3025f8dbe1 147 SUPERFAMILY SSF47240 5 141 3.1E-8 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07335 b5f47792f96aa3d52d965a3025f8dbe1 147 Pfam PF02915 Rubrerythrin 8 141 4.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_02995 1cebc028e9f40de01abb90ca56302947 650 Gene3D G3DSA:2.30.310.10 5 150 4.6E-31 T 23-10-2018 A3L14_02995 1cebc028e9f40de01abb90ca56302947 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 435 8.2E-84 T 23-10-2018 A3L14_02995 1cebc028e9f40de01abb90ca56302947 650 Pfam PF05670 Domain of unknown function (DUF814) 455 553 2.3E-26 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A3L14_02995 1cebc028e9f40de01abb90ca56302947 650 SUPERFAMILY SSF46946 182 222 8.71E-5 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 SUPERFAMILY SSF53681 4 117 1.01E-36 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 229 3.3E-102 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 SUPERFAMILY SSF53681 119 227 1.29E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 Gene3D G3DSA:3.40.50.1860 107 214 5.0E-89 T 23-10-2018 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 Gene3D G3DSA:3.40.50.1860 6 220 5.0E-89 T 23-10-2018 A3L14_05960 4df0ddd9b07d34a43727281d2828ba1f 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 3.7E-64 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_09900 491831cbdf4bdd0cafe42ea8a0bd35cf 176 Pfam PF01883 Iron-sulfur cluster assembly protein 80 153 6.3E-22 T 23-10-2018 IPR002744 MIP18 family-like A3L14_09900 491831cbdf4bdd0cafe42ea8a0bd35cf 176 SUPERFAMILY SSF117916 77 174 4.25E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L14_09900 491831cbdf4bdd0cafe42ea8a0bd35cf 176 Gene3D G3DSA:3.30.300.130 73 175 1.6E-35 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L14_00795 8f8a1526b88199b6b95790d815669b14 351 SUPERFAMILY SSF161098 119 327 5.36E-14 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00795 8f8a1526b88199b6b95790d815669b14 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 344 2.4E-35 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00795 8f8a1526b88199b6b95790d815669b14 351 Gene3D G3DSA:1.10.3720.10 115 341 4.1E-16 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_06995 14860aa09b54120f13c1d7eb3ed71480 385 SUPERFAMILY SSF53383 29 382 2.82E-132 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_06995 14860aa09b54120f13c1d7eb3ed71480 385 Gene3D G3DSA:3.40.640.10 1 248 3.7E-102 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_06995 14860aa09b54120f13c1d7eb3ed71480 385 Gene3D G3DSA:3.90.1150.10 249 385 1.8E-62 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_06995 14860aa09b54120f13c1d7eb3ed71480 385 PIRSF PIRSF001434 1 384 2.2E-163 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A3L14_06995 14860aa09b54120f13c1d7eb3ed71480 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 381 3.4E-165 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 SUPERFAMILY SSF51905 5 459 3.38E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 Gene3D G3DSA:3.50.50.60 416 456 3.7E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 Gene3D G3DSA:3.50.50.60 133 229 1.5E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 Gene3D G3DSA:3.50.50.60 2 90 5.8E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 1.7E-11 T 23-10-2018 A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.7E-11 T 23-10-2018 A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 Pfam PF01946 Thi4 family 7 37 5.5E-7 T 23-10-2018 A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 PIRSF PIRSF038984 2 85 5.3E-9 T 23-10-2018 IPR028348 FAD dependent protein A3L14_00550 f7ced9476dd9d7fee7f52b2b57c50655 483 PIRSF PIRSF038984 132 463 2.3E-25 T 23-10-2018 IPR028348 FAD dependent protein A3L14_00530 55d27977a2a401629ff06ac6593ff825 218 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 216 1.6E-47 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_00530 55d27977a2a401629ff06ac6593ff825 218 Gene3D G3DSA:3.40.50.11570 7 218 2.2E-48 T 23-10-2018 A3L14_11370 62ef205d16b8ed036d9a0aaa271363e2 163 Pfam PF13237 4Fe-4S dicluster domain 59 108 3.7E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_11370 62ef205d16b8ed036d9a0aaa271363e2 163 Gene3D G3DSA:3.30.70.3270 46 163 1.8E-15 T 23-10-2018 A3L14_11370 62ef205d16b8ed036d9a0aaa271363e2 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_11370 62ef205d16b8ed036d9a0aaa271363e2 163 SUPERFAMILY SSF54862 54 110 1.81E-17 T 23-10-2018 A3L14_11370 62ef205d16b8ed036d9a0aaa271363e2 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_05305 eca3ff72faaa92d3244a7ab8cecf444f 157 SUPERFAMILY SSF88723 2 143 8.41E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05305 eca3ff72faaa92d3244a7ab8cecf444f 157 Pfam PF01850 PIN domain 2 144 1.4E-15 T 23-10-2018 IPR002716 PIN domain A3L14_05305 eca3ff72faaa92d3244a7ab8cecf444f 157 SMART SM00670 1 142 4.6E-4 T 23-10-2018 IPR002716 PIN domain A3L14_05305 eca3ff72faaa92d3244a7ab8cecf444f 157 Gene3D G3DSA:3.40.50.1010 1 152 2.1E-9 T 23-10-2018 A3L14_03205 a618b3a99cf1ab485eed93806fb5f78f 319 SUPERFAMILY SSF48452 77 218 1.58E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_03205 a618b3a99cf1ab485eed93806fb5f78f 319 SMART SM00028 121 154 0.77 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_03205 a618b3a99cf1ab485eed93806fb5f78f 319 SMART SM00028 81 114 30.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_03205 a618b3a99cf1ab485eed93806fb5f78f 319 Gene3D G3DSA:1.25.40.10 40 312 1.8E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_03205 a618b3a99cf1ab485eed93806fb5f78f 319 Pfam PF13424 Tetratricopeptide repeat 86 153 3.5E-8 T 23-10-2018 A3L14_10225 a791ea6ce5a0a23e5838ab7dd05ab3db 338 Pfam PF01032 FecCD transport family 13 330 4.8E-82 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L14_10225 a791ea6ce5a0a23e5838ab7dd05ab3db 338 SUPERFAMILY SSF81345 4 330 2.09E-74 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L14_10225 a791ea6ce5a0a23e5838ab7dd05ab3db 338 Gene3D G3DSA:1.10.3470.10 2 335 3.1E-89 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 49.022 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Gene3D G3DSA:3.30.1490.20 114 174 2.7E-97 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Pfam PF06973 Domain of unknown function (DUF1297) 156 331 3.6E-71 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Gene3D G3DSA:3.40.50.20 1 85 1.6E-28 T 23-10-2018 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 SUPERFAMILY SSF52440 1 97 2.78E-30 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 4.1E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 PIRSF PIRSF004602 1 331 2.9E-132 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 SUPERFAMILY SSF56059 102 331 1.85E-78 T 23-10-2018 A3L14_01430 1c531a768493fdc3eb18ccacb172b9e6 331 Gene3D G3DSA:3.30.470.20 87 330 2.7E-97 T 23-10-2018 A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.456 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 SUPERFAMILY SSF52080 5 147 3.4E-34 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 3.5E-20 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 Gene3D G3DSA:4.10.990.10 4 52 1.4E-9 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 Gene3D G3DSA:3.100.10.10 63 148 7.6E-24 T 23-10-2018 A3L14_02590 97235fad043a5a1bf510202a88d23ff9 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07950 595fd9a0c849a3225b45ea518b23efae 313 Gene3D G3DSA:1.20.1420.30 35 296 2.0E-81 T 23-10-2018 A3L14_07950 595fd9a0c849a3225b45ea518b23efae 313 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 297 2.7E-61 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A3L14_07950 595fd9a0c849a3225b45ea518b23efae 313 Pfam PF01699 Sodium/calcium exchanger protein 5 143 2.0E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L14_07950 595fd9a0c849a3225b45ea518b23efae 313 Pfam PF01699 Sodium/calcium exchanger protein 165 303 1.1E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L14_07950 595fd9a0c849a3225b45ea518b23efae 313 Gene3D G3DSA:1.20.58.1130 8 195 2.0E-81 T 23-10-2018 A3L14_11470 9b769df430df4aea4895908369b1e133 278 SUPERFAMILY SSF102114 13 232 3.53E-28 T 23-10-2018 A3L14_11470 9b769df430df4aea4895908369b1e133 278 SMART SM00729 16 219 3.4E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_11470 9b769df430df4aea4895908369b1e133 278 Pfam PF04055 Radical SAM superfamily 23 162 1.9E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_11470 9b769df430df4aea4895908369b1e133 278 Gene3D G3DSA:3.20.20.70 1 244 7.7E-18 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_11375 4515970e5d09ea6f1da1122cfb701c8f 170 Gene3D G3DSA:1.20.1260.10 9 156 2.7E-22 T 23-10-2018 IPR012347 Ferritin-like A3L14_11375 4515970e5d09ea6f1da1122cfb701c8f 170 Pfam PF02915 Rubrerythrin 17 85 2.3E-5 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_11375 4515970e5d09ea6f1da1122cfb701c8f 170 Pfam PF02915 Rubrerythrin 105 162 1.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_11375 4515970e5d09ea6f1da1122cfb701c8f 170 SUPERFAMILY SSF47240 14 157 3.95E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 Pfam PF03176 MMPL family 45 404 1.1E-35 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 Pfam PF03176 MMPL family 527 744 2.2E-22 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 SUPERFAMILY SSF82866 558 749 3.4E-36 T 23-10-2018 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 Gene3D G3DSA:1.20.1640.10 590 752 8.6E-13 T 23-10-2018 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 Gene3D G3DSA:1.20.1640.10 192 373 1.7E-23 T 23-10-2018 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 SUPERFAMILY SSF82866 145 364 4.71E-42 T 23-10-2018 A3L14_00015 be978cf98decc8c6cf9980250ca2622a 755 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 12 744 3.8E-226 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 A3L14_02950 eb14e21dfb4958cd20147938ec873266 76 SUPERFAMILY SSF89447 2 56 3.01E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_02950 eb14e21dfb4958cd20147938ec873266 76 Gene3D G3DSA:2.40.330.20 1 74 9.4E-6 T 23-10-2018 IPR038619 MraZ superfamily A3L14_02950 eb14e21dfb4958cd20147938ec873266 76 SMART SM00966 3 44 0.0014 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 Gene3D G3DSA:3.40.50.1000 2 215 2.6E-64 T 23-10-2018 IPR023214 HAD superfamily A3L14_02025 05761ef4c89290a391d67cff17799e45 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 4.7E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 4.7E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 4.7E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 4.7E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 96 199 4.8E-14 T 23-10-2018 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 Gene3D G3DSA:1.10.150.400 14 92 2.6E-64 T 23-10-2018 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 134 193 2.8E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_02025 05761ef4c89290a391d67cff17799e45 234 SUPERFAMILY SSF56784 1 226 5.08E-32 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Gene3D G3DSA:3.10.20.440 1 95 1.9E-37 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 257 2.3E-9 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Gene3D G3DSA:1.10.10.1100 399 475 5.5E-143 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 267 353 5.2E-7 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Gene3D G3DSA:3.50.50.60 110 481 5.5E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 1.2E-14 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 5.2E-8 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 5.2E-8 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 318 5.2E-8 T 23-10-2018 A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 SUPERFAMILY SSF51905 109 375 7.56E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09695 b9587b821a0bc4efa68f482b3922d964 499 Gene3D G3DSA:3.50.50.60 220 310 5.5E-143 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_08750 00c9db45a91ed9ecf4ea0f90c2336b89 160 SMART SM00670 1 142 4.7E-6 T 23-10-2018 IPR002716 PIN domain A3L14_08750 00c9db45a91ed9ecf4ea0f90c2336b89 160 Gene3D G3DSA:3.40.50.1010 1 150 1.8E-10 T 23-10-2018 A3L14_08750 00c9db45a91ed9ecf4ea0f90c2336b89 160 SUPERFAMILY SSF88723 2 144 2.8E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08750 00c9db45a91ed9ecf4ea0f90c2336b89 160 Pfam PF01850 PIN domain 2 144 1.7E-19 T 23-10-2018 IPR002716 PIN domain A3L14_00060 461ff3037c68ba1d5425960c5a5960e4 173 Gene3D G3DSA:2.30.110.10 1 168 1.3E-42 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L14_00060 461ff3037c68ba1d5425960c5a5960e4 173 SMART SM00903 5 146 1.1E-18 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L14_00060 461ff3037c68ba1d5425960c5a5960e4 173 SUPERFAMILY SSF50475 4 166 6.38E-37 T 23-10-2018 A3L14_00060 461ff3037c68ba1d5425960c5a5960e4 173 Pfam PF01613 Flavin reductase like domain 8 140 4.9E-21 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 SUPERFAMILY SSF56655 10 252 2.75E-55 T 23-10-2018 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 Gene3D G3DSA:3.30.540.10 6 143 1.0E-35 T 23-10-2018 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 Pfam PF00459 Inositol monophosphatase family 11 258 1.7E-34 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 Gene3D G3DSA:3.40.190.80 145 258 2.6E-27 T 23-10-2018 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 168 189 6.1E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 6.1E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 6.1E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 6.1E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_08330 275a3b57c8aaa6d87e81e7024a76f0a1 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 6.1E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 SUPERFAMILY SSF51230 517 594 3.14E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 Pfam PF00364 Biotin-requiring enzyme 528 593 3.1E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 Gene3D G3DSA:2.40.50.100 520 594 5.8E-30 T 23-10-2018 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 Gene3D G3DSA:3.20.20.70 2 457 8.0E-161 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 Pfam PF00682 HMGL-like 4 234 4.1E-39 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 SUPERFAMILY SSF51569 4 301 3.48E-83 T 23-10-2018 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 550 567 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 SUPERFAMILY SSF89000 297 447 2.94E-53 T 23-10-2018 A3L14_07510 bc2a1b34205b7b56b95fbba98636a1ec 594 Pfam PF02436 Conserved carboxylase domain 292 474 4.4E-56 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A3L14_05940 a343c01b820022066c143a343bc49c89 160 Gene3D G3DSA:3.30.70.920 57 160 2.5E-31 T 23-10-2018 A3L14_05940 a343c01b820022066c143a343bc49c89 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.8E-14 T 23-10-2018 A3L14_05940 a343c01b820022066c143a343bc49c89 160 SMART SM00344 4 105 2.7E-9 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_05940 a343c01b820022066c143a343bc49c89 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05940 a343c01b820022066c143a343bc49c89 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05940 a343c01b820022066c143a343bc49c89 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.4E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05940 a343c01b820022066c143a343bc49c89 160 Gene3D G3DSA:1.10.10.10 1 56 4.1E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_05940 a343c01b820022066c143a343bc49c89 160 SUPERFAMILY SSF46785 3 58 3.96E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 122 4.0E-28 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 220 4.7E-9 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 SUPERFAMILY SSF55347 127 290 1.36E-31 T 23-10-2018 A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 Gene3D G3DSA:3.30.360.10 124 315 5.6E-47 T 23-10-2018 A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 SUPERFAMILY SSF51735 2 150 1.86E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00415 668273e8664a6a6ed80fa9d4916d4423 315 Gene3D G3DSA:3.40.50.720 1 123 1.7E-32 T 23-10-2018 A3L14_10185 37d8ae6a50d65677e20d6e595dd3c1c9 73 Pfam PF05763 Protein of unknown function (DUF835) 5 66 1.6E-17 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_01670 af1df61ba0f73fd782f628a88e676871 130 Gene3D G3DSA:1.10.10.10 1 50 4.3E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01670 af1df61ba0f73fd782f628a88e676871 130 Pfam PF08281 Sigma-70, region 4 3 46 4.9E-6 T 23-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A3L14_01670 af1df61ba0f73fd782f628a88e676871 130 SUPERFAMILY SSF88659 9 48 4.58E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L14_07435 da06d679a98252e33f36f53468a0058d 195 Gene3D G3DSA:3.40.50.880 1 194 2.2E-61 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_07435 da06d679a98252e33f36f53468a0058d 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 193 1.9E-59 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L14_07435 da06d679a98252e33f36f53468a0058d 195 Pfam PF00117 Glutamine amidotransferase class-I 35 187 1.6E-18 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L14_07435 da06d679a98252e33f36f53468a0058d 195 PIRSF PIRSF000495 1 195 5.4E-56 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L14_07435 da06d679a98252e33f36f53468a0058d 195 SUPERFAMILY SSF52317 1 193 1.39E-46 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_07435 da06d679a98252e33f36f53468a0058d 195 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 195 33.583 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A3L14_04295 3aee1a6fd5e63ce3f4e7e0342dda1267 206 SUPERFAMILY SSF160975 23 199 6.15E-90 T 23-10-2018 A3L14_04295 3aee1a6fd5e63ce3f4e7e0342dda1267 206 Gene3D G3DSA:1.10.150.280 93 190 6.3E-42 T 23-10-2018 A3L14_04295 3aee1a6fd5e63ce3f4e7e0342dda1267 206 Gene3D G3DSA:2.40.50.140 23 92 2.8E-22 T 23-10-2018 A3L14_04295 3aee1a6fd5e63ce3f4e7e0342dda1267 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 3.8E-67 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A3L14_06535 3fff7047932710dbe28b13443d5954e7 267 Gene3D G3DSA:3.10.270.10 1 266 1.3E-67 T 23-10-2018 A3L14_06535 3fff7047932710dbe28b13443d5954e7 267 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 267 26.717 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 A3L14_06535 3fff7047932710dbe28b13443d5954e7 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 3 263 1.6E-65 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 Gene3D G3DSA:3.10.580.10 64 186 2.4E-27 T 23-10-2018 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 SUPERFAMILY SSF54631 68 184 1.64E-26 T 23-10-2018 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 SMART SM00116 141 187 0.27 T 23-10-2018 IPR000644 CBS domain A3L14_05135 bdca931d08894febb288b024dca1ce71 190 SMART SM00116 77 124 7.2E-7 T 23-10-2018 IPR000644 CBS domain A3L14_05135 bdca931d08894febb288b024dca1ce71 190 SUPERFAMILY SSF47413 11 60 2.57E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 PIRSF PIRSF037253 2 190 1.6E-80 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A3L14_05135 bdca931d08894febb288b024dca1ce71 190 Gene3D G3DSA:1.10.260.40 10 63 1.2E-16 T 23-10-2018 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 Pfam PF01381 Helix-turn-helix 13 60 1.1E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 SMART SM00530 12 68 2.7E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_05135 bdca931d08894febb288b024dca1ce71 190 Pfam PF00571 CBS domain 134 184 6.0E-7 T 23-10-2018 IPR000644 CBS domain A3L14_05135 bdca931d08894febb288b024dca1ce71 190 Pfam PF00571 CBS domain 70 121 1.0E-11 T 23-10-2018 IPR000644 CBS domain A3L14_00050 29c25ab3d5a9cf2e773a7fe9acfdf976 262 Pfam PF05763 Protein of unknown function (DUF835) 132 248 1.8E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_08720 be564fa8de9748cf04eb964466032ba1 292 Gene3D G3DSA:3.40.50.10890 128 171 1.5E-23 T 23-10-2018 A3L14_08720 be564fa8de9748cf04eb964466032ba1 292 SUPERFAMILY SSF56281 14 279 3.38E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_08720 be564fa8de9748cf04eb964466032ba1 292 Gene3D G3DSA:3.60.15.10 50 127 1.5E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_09920 f81c5e87866d5c06d9c7d1ed7966901b 298 Hamap MF_01406 UPF0282 protein . 1 285 38.184 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L14_09920 f81c5e87866d5c06d9c7d1ed7966901b 298 Pfam PF12706 Beta-lactamase superfamily domain 27 204 1.4E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_09920 f81c5e87866d5c06d9c7d1ed7966901b 298 PIRSF PIRSF004944 1 298 1.7E-111 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L14_09920 f81c5e87866d5c06d9c7d1ed7966901b 298 SUPERFAMILY SSF56281 1 259 3.01E-16 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_09920 f81c5e87866d5c06d9c7d1ed7966901b 298 Gene3D G3DSA:3.60.15.10 7 268 2.6E-14 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_07160 f2a825ca8a92fbe1c5fd4ba486e43002 65 Pfam PF11127 Protein of unknown function (DUF2892) 1 64 6.2E-20 T 23-10-2018 IPR021309 Protein of unknown function DUF2892 A3L14_11110 b782ad66de0c453933a926c12dfd2762 83 Hamap MF_00342 UPF0147 protein . 1 83 29.55 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L14_11110 b782ad66de0c453933a926c12dfd2762 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 3 82 3.5E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L14_11110 b782ad66de0c453933a926c12dfd2762 83 SUPERFAMILY SSF158436 3 83 1.44E-29 T 23-10-2018 A3L14_11110 b782ad66de0c453933a926c12dfd2762 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 3.0E-38 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L14_11110 b782ad66de0c453933a926c12dfd2762 83 Gene3D G3DSA:1.20.1440.50 2 83 3.2E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 Gene3D G3DSA:3.40.50.920 256 396 2.5E-44 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 SUPERFAMILY SSF52922 257 378 3.93E-36 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 242 4.1E-78 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 SUPERFAMILY SSF52518 8 254 2.7E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 266 369 3.0E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L14_10585 8551b515a7ffc5668a44e6289d74098c 396 Gene3D G3DSA:3.40.50.970 7 255 2.9E-99 T 23-10-2018 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Pfam PF00037 4Fe-4S binding domain 613 634 5.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 SUPERFAMILY SSF54862 578 635 3.81E-12 T 23-10-2018 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 PIRSF PIRSF006439 3 640 4.1E-189 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 SUPERFAMILY SSF52518 384 568 8.25E-29 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 SUPERFAMILY SSF52518 15 191 6.78E-50 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 SUPERFAMILY SSF52922 256 315 2.36E-8 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Gene3D G3DSA:3.40.50.970 394 569 1.6E-20 T 23-10-2018 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 205 7.8E-16 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Gene3D G3DSA:3.40.50.970 3 192 4.8E-49 T 23-10-2018 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 619 630 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 418 558 1.3E-25 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_07190 646271a9c5bf36862d17bb01ef3c4341 666 Gene3D G3DSA:3.30.70.20 581 644 3.9E-9 T 23-10-2018 A3L14_07875 082783dc7244ba31b46bfecd0c03c570 420 SUPERFAMILY SSF51338 12 404 2.72E-24 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_07875 082783dc7244ba31b46bfecd0c03c570 420 SUPERFAMILY SSF51556 54 344 3.08E-79 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_07875 082783dc7244ba31b46bfecd0c03c570 420 Gene3D G3DSA:2.30.40.10 6 401 1.0E-114 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_07875 082783dc7244ba31b46bfecd0c03c570 420 Gene3D G3DSA:3.20.20.140 55 341 1.0E-114 T 23-10-2018 A3L14_07875 082783dc7244ba31b46bfecd0c03c570 420 Pfam PF01979 Amidohydrolase family 51 395 6.4E-56 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 Gene3D G3DSA:1.10.10.10 6 78 1.2E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 Pfam PF01037 Lrp/AsnC ligand binding domain 89 152 2.3E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 SMART SM00419 21 72 4.3E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 Pfam PF12802 MarR family 7 65 7.0E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 SUPERFAMILY SSF46785 31 135 1.54E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_01850 b1d1084b7e8747fef46f19286057e274 154 Gene3D G3DSA:3.30.70.920 79 154 6.8E-10 T 23-10-2018 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.212 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 Gene3D G3DSA:3.40.50.1580 1 257 1.2E-103 T 23-10-2018 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 3 238 2.5E-101 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 Pfam PF01048 Phosphorylase superfamily 3 237 3.2E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L14_00155 6f6b109ea7bdef390f9b7bdeea3461ac 257 SUPERFAMILY SSF53167 1 255 4.32E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L14_00335 e0805e5b02210abc03cd380d30750766 317 PIRSF PIRSF002849 1 316 6.7E-139 T 23-10-2018 A3L14_00335 e0805e5b02210abc03cd380d30750766 317 Gene3D G3DSA:1.10.8.300 202 311 1.4E-37 T 23-10-2018 A3L14_00335 e0805e5b02210abc03cd380d30750766 317 Gene3D G3DSA:3.40.50.300 21 187 1.3E-47 T 23-10-2018 A3L14_00335 e0805e5b02210abc03cd380d30750766 317 SUPERFAMILY SSF52540 15 287 4.53E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00335 e0805e5b02210abc03cd380d30750766 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 1.5E-67 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L14_04455 b216d4395eacc89559278b37ee52977c 362 SUPERFAMILY SSF51735 1 168 3.53E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_04455 b216d4395eacc89559278b37ee52977c 362 SUPERFAMILY SSF55347 118 258 2.75E-38 T 23-10-2018 A3L14_04455 b216d4395eacc89559278b37ee52977c 362 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 2.6E-29 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A3L14_04455 b216d4395eacc89559278b37ee52977c 362 Gene3D G3DSA:3.40.50.720 2 349 6.5E-130 T 23-10-2018 A3L14_04455 b216d4395eacc89559278b37ee52977c 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 8.4E-20 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A3L14_04455 b216d4395eacc89559278b37ee52977c 362 Gene3D G3DSA:3.30.360.10 118 299 6.5E-130 T 23-10-2018 A3L14_02850 f4132f44bd00da511fa771343f8ddbb7 140 Gene3D G3DSA:1.20.120.580 4 140 1.5E-16 T 23-10-2018 IPR037038 Bsu32300-like superfamily A3L14_02850 f4132f44bd00da511fa771343f8ddbb7 140 Pfam PF01934 Protein of unknown function DUF86 13 132 9.4E-25 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A3L14_07975 20162921b985f43c9c4b087d6c6234fe 1498 Pfam PF13604 AAA domain 963 1164 7.4E-13 T 23-10-2018 A3L14_07975 20162921b985f43c9c4b087d6c6234fe 1498 Gene3D G3DSA:3.40.50.300 1231 1454 3.6E-34 T 23-10-2018 A3L14_07975 20162921b985f43c9c4b087d6c6234fe 1498 SUPERFAMILY SSF52540 962 1479 9.76E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07975 20162921b985f43c9c4b087d6c6234fe 1498 Pfam PF13087 AAA domain 1223 1421 1.4E-24 T 23-10-2018 A3L14_04735 c0ee27416fe618bc70c5838c1d306f0d 199 Gene3D G3DSA:3.40.30.10 12 117 3.8E-10 T 23-10-2018 A3L14_04735 c0ee27416fe618bc70c5838c1d306f0d 199 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 178 197 2.3E-5 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_04735 c0ee27416fe618bc70c5838c1d306f0d 199 SUPERFAMILY SSF52833 15 108 1.76E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Pfam PF08271 TFIIB zinc-binding 6 47 2.1E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Gene3D G3DSA:1.10.472.10 207 299 7.7E-28 T 23-10-2018 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 SUPERFAMILY SSF47954 206 298 4.9E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 SUPERFAMILY SSF47954 113 200 6.81E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Gene3D G3DSA:1.10.472.170 6 197 4.0E-68 T 23-10-2018 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.742 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 SUPERFAMILY SSF57783 4 50 2.1E-17 T 23-10-2018 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 3.5E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 SMART SM00385 114 195 1.8E-12 T 23-10-2018 IPR013763 Cyclin-like A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 SMART SM00385 210 291 7.8E-13 T 23-10-2018 IPR013763 Cyclin-like A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 1.7E-22 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L14_08655 c894f511219cdcc25e6b16dccb2f1d8f 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.3E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L14_09610 8c1cc6e1da07f09cf1c14d5777e6e0ac 418 Pfam PF00155 Aminotransferase class I and II 62 405 1.2E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_09610 8c1cc6e1da07f09cf1c14d5777e6e0ac 418 Gene3D G3DSA:3.40.640.10 79 304 3.2E-163 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_09610 8c1cc6e1da07f09cf1c14d5777e6e0ac 418 SUPERFAMILY SSF53383 16 411 2.04E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_09610 8c1cc6e1da07f09cf1c14d5777e6e0ac 418 Gene3D G3DSA:3.90.1150.10 34 410 3.2E-163 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_08745 eab5cb318385b9e4485a3f90acd144c9 133 Gene3D G3DSA:3.40.140.10 3 133 6.4E-28 T 23-10-2018 A3L14_08745 eab5cb318385b9e4485a3f90acd144c9 133 SMART SM00232 2 132 3.3E-15 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A3L14_08745 eab5cb318385b9e4485a3f90acd144c9 133 Pfam PF14464 Prokaryotic homologs of the JAB domain 19 109 1.4E-15 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L14_08745 eab5cb318385b9e4485a3f90acd144c9 133 SUPERFAMILY SSF102712 3 126 2.09E-23 T 23-10-2018 A3L14_06410 1ec036aefb5339377c5183ef20c92b88 263 Pfam PF13230 Glutamine amidotransferases class-II 30 123 9.9E-7 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A3L14_06410 1ec036aefb5339377c5183ef20c92b88 263 SUPERFAMILY SSF56235 40 233 1.54E-14 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_06410 1ec036aefb5339377c5183ef20c92b88 263 Gene3D G3DSA:3.60.20.10 19 224 1.5E-12 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_04600 443138c25a759fb5f3f88099cdc8c50b 110 Gene3D G3DSA:3.30.300.100 1 110 2.5E-42 T 23-10-2018 IPR035954 MTH677-like superfamily A3L14_04600 443138c25a759fb5f3f88099cdc8c50b 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 1.2E-26 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 PIRSF PIRSF004932 3 146 2.6E-65 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 Gene3D G3DSA:3.30.1190.10 17 135 6.4E-36 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 137 6.2E-58 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 Pfam PF14601 DNA_binding protein, TFX, C-term 52 132 7.7E-23 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 SUPERFAMILY SSF89915 17 121 1.05E-22 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L14_10890 652906d34c85f00ea6dc8e8836198eac 146 Pfam PF04545 Sigma-70, region 4 7 49 2.7E-6 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A3L14_02390 17f7e150ff4970646e1dc8ab124e8656 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_02390 17f7e150ff4970646e1dc8ab124e8656 334 Gene3D G3DSA:1.10.1060.10 283 332 1.9E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_02390 17f7e150ff4970646e1dc8ab124e8656 334 SUPERFAMILY SSF46548 224 331 9.77E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_02390 17f7e150ff4970646e1dc8ab124e8656 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_02390 17f7e150ff4970646e1dc8ab124e8656 334 Pfam PF17179 4Fe-4S dicluster domain 229 320 3.1E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_06675 e8da6e5dde2497b4f076cb1ddc89fbfc 148 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 3.1E-23 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 A3L14_10670 53f9accb5ecc4c5aba3268aba35c0327 195 Pfam PF01949 Protein of unknown function DUF99 8 188 1.0E-65 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L14_10670 53f9accb5ecc4c5aba3268aba35c0327 195 Gene3D G3DSA:3.30.2170.10 3 195 4.8E-61 T 23-10-2018 A3L14_10670 53f9accb5ecc4c5aba3268aba35c0327 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 191 6.0E-36 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L14_10670 53f9accb5ecc4c5aba3268aba35c0327 195 Hamap MF_00582 UPF0215 protein . 9 189 34.407 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L14_10670 53f9accb5ecc4c5aba3268aba35c0327 195 PIRSF PIRSF006380 1 195 4.9E-71 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L14_00125 28e55dc5579893385f9782e8134da869 338 PRINTS PR01333 Two pore domain K+ channel signature 121 130 2.6E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A3L14_00125 28e55dc5579893385f9782e8134da869 338 PRINTS PR01333 Two pore domain K+ channel signature 57 85 2.6E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A3L14_00125 28e55dc5579893385f9782e8134da869 338 SUPERFAMILY SSF51735 116 264 4.19E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_00125 28e55dc5579893385f9782e8134da869 338 Pfam PF07885 Ion channel 29 101 2.1E-16 T 23-10-2018 IPR013099 Potassium channel domain A3L14_00125 28e55dc5579893385f9782e8134da869 338 SUPERFAMILY SSF81324 10 137 8.24E-29 T 23-10-2018 A3L14_00125 28e55dc5579893385f9782e8134da869 338 Gene3D G3DSA:3.40.50.720 116 266 8.0E-27 T 23-10-2018 A3L14_00125 28e55dc5579893385f9782e8134da869 338 Pfam PF02254 TrkA-N domain 121 241 1.5E-17 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L14_00125 28e55dc5579893385f9782e8134da869 338 Gene3D G3DSA:1.10.287.70 5 102 4.1E-22 T 23-10-2018 A3L14_00755 77cdb03db2425867c8998a3bd183def4 418 SUPERFAMILY SSF161098 204 403 6.02E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00755 77cdb03db2425867c8998a3bd183def4 418 Gene3D G3DSA:1.10.3720.10 202 413 4.9E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00755 77cdb03db2425867c8998a3bd183def4 418 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 409 3.7E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00595 93c29de9195a8799093ada091ba6382f 91 SUPERFAMILY SSF46785 3 85 1.87E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_00595 93c29de9195a8799093ada091ba6382f 91 Gene3D G3DSA:1.10.10.10 1 90 2.8E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00595 93c29de9195a8799093ada091ba6382f 91 Pfam PF14947 Winged helix-turn-helix 2 77 1.4E-23 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 Gene3D G3DSA:2.30.30.30 1 70 1.7E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 2.0E-10 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 SUPERFAMILY SSF50249 71 133 5.57E-14 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 PIRSF PIRSF003025 1 136 4.5E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 SUPERFAMILY SSF50104 5 78 8.53E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.382 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 Gene3D G3DSA:2.40.50.140 71 135 9.3E-29 T 23-10-2018 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 SMART SM01376 70 134 4.9E-15 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L14_04440 f6ede8caf6e05f35858a10b68d9d406c 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 2.8E-47 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L14_03075 c9fb112fa41d2fd033dec7a9701e3fb7 466 PIRSF PIRSF006603 2 465 1.0E-142 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03075 c9fb112fa41d2fd033dec7a9701e3fb7 466 Pfam PF01554 MatE 264 418 6.6E-24 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03075 c9fb112fa41d2fd033dec7a9701e3fb7 466 Pfam PF01554 MatE 27 186 4.1E-34 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03075 c9fb112fa41d2fd033dec7a9701e3fb7 466 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 424 1.6E-72 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_10270 93eaed6e515babe9b161f10bca74de45 142 Pfam PF01850 PIN domain 11 134 1.4E-15 T 23-10-2018 IPR002716 PIN domain A3L14_10270 93eaed6e515babe9b161f10bca74de45 142 Gene3D G3DSA:3.40.50.1010 10 141 3.1E-23 T 23-10-2018 A3L14_10270 93eaed6e515babe9b161f10bca74de45 142 SUPERFAMILY SSF88723 11 139 7.06E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_10270 93eaed6e515babe9b161f10bca74de45 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 10 142 9.467 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_06645 81be4a9c7a110f4caac2f42e38fb913d 134 SMART SM00470 36 124 1.4E-5 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L14_06645 81be4a9c7a110f4caac2f42e38fb913d 134 SUPERFAMILY SSF110849 32 104 5.76E-13 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L14_06645 81be4a9c7a110f4caac2f42e38fb913d 134 Gene3D G3DSA:3.90.1530.10 17 121 1.1E-8 T 23-10-2018 A3L14_06645 81be4a9c7a110f4caac2f42e38fb913d 134 Pfam PF02195 ParB-like nuclease domain 38 104 7.4E-10 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L14_02070 8a6d46e66dc2aa886fc322b203543444 96 Gene3D G3DSA:1.10.10.10 1 94 2.6E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_02070 8a6d46e66dc2aa886fc322b203543444 96 SUPERFAMILY SSF46785 2 91 8.96E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02070 8a6d46e66dc2aa886fc322b203543444 96 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 2.4E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_03790 bef035f8ccddd1eca68a2fca0cfb23d6 232 SUPERFAMILY SSF56059 23 232 1.2E-50 T 23-10-2018 A3L14_03790 bef035f8ccddd1eca68a2fca0cfb23d6 232 Gene3D G3DSA:3.30.1490.20 39 116 4.4E-90 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_03790 bef035f8ccddd1eca68a2fca0cfb23d6 232 Pfam PF13549 ATP-grasp domain 16 231 8.1E-83 T 23-10-2018 A3L14_03790 bef035f8ccddd1eca68a2fca0cfb23d6 232 Gene3D G3DSA:3.30.470.20 21 230 4.4E-90 T 23-10-2018 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 SMART SM00950 454 736 2.3E-15 T 23-10-2018 IPR003165 Piwi domain GO:0003676 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 Gene3D G3DSA:3.30.420.10 527 750 2.0E-45 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 SUPERFAMILY SSF101690 4 308 6.04E-40 T 23-10-2018 IPR036085 PAZ domain superfamily GO:0005515 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 Pfam PF12212 PAZ domain 142 266 1.6E-38 T 23-10-2018 IPR021103 Argonaute PAZ domain, archaea A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 Gene3D G3DSA:2.170.260.20 140 267 3.9E-77 T 23-10-2018 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 SUPERFAMILY SSF53098 343 750 9.86E-66 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 Gene3D G3DSA:3.40.50.2300 328 526 1.6E-55 T 23-10-2018 A3L14_06700 09c77923dcda587b3bf8dc29997041ec 750 Pfam PF02171 Piwi domain 467 735 4.0E-16 T 23-10-2018 IPR003165 Piwi domain GO:0003676 A3L14_07405 9cd5d02c6229ebe5bbd193918cf6afa0 107 PIRSF PIRSF019108 1 107 3.3E-40 T 23-10-2018 IPR016748 Transcription regulator, CopG/Arc/MetJ DNA-binding domain-containing, predicted A3L14_07405 9cd5d02c6229ebe5bbd193918cf6afa0 107 SUPERFAMILY SSF47598 8 49 1.67E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 Gene3D G3DSA:3.90.180.10 21 338 1.1E-133 T 23-10-2018 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 6.4E-179 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 6.4E-29 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 SUPERFAMILY SSF50129 3 177 2.13E-54 T 23-10-2018 IPR011032 GroES-like superfamily A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 SUPERFAMILY SSF51735 146 310 8.41E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 Gene3D G3DSA:3.40.50.720 157 291 1.1E-133 T 23-10-2018 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 SMART SM00829 16 345 2.0E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 53.835 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L14_04230 a7a728fe59cee1ae98528f8f236c551f 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 1.3E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 Pfam PF01200 Ribosomal protein S28e 4 66 7.7E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 SUPERFAMILY SSF50249 3 69 2.14E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 Gene3D G3DSA:2.40.50.140 1 70 7.9E-32 T 23-10-2018 A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 2.0E-8 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_07830 68f87f0a96fedfd3798f86d06fa72d39 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 24.833 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 Gene3D G3DSA:3.40.50.300 1 243 2.7E-76 T 23-10-2018 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 Gene3D G3DSA:2.40.50.140 310 354 1.3E-25 T 23-10-2018 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 SUPERFAMILY SSF52540 4 249 9.06E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 Pfam PF00005 ABC transporter 20 167 7.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 Gene3D G3DSA:2.40.50.100 245 304 1.6E-23 T 23-10-2018 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 SMART SM00382 28 217 1.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 Pfam PF08402 TOBE domain 288 363 6.9E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L14_00930 fd161065a5a2e2b8bfa5fa5d239e8861 372 SUPERFAMILY SSF50331 242 370 2.67E-24 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 Gene3D G3DSA:1.10.10.10 281 358 2.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 SUPERFAMILY SSF46785 283 357 2.4E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 SUPERFAMILY SSF52540 1 278 2.0E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 Gene3D G3DSA:3.40.50.300 1 203 3.7E-37 T 23-10-2018 A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 Gene3D G3DSA:1.10.8.60 205 280 3.4E-23 T 23-10-2018 A3L14_06775 4398cf26bd4ff1ab7094e7bcc2b81717 359 Pfam PF01637 ATPase domain predominantly from Archaea 15 244 2.7E-15 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_09155 9690dd9a5cd8514501480cb9bdc75fd9 198 Gene3D G3DSA:1.10.10.10 4 105 8.1E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09155 9690dd9a5cd8514501480cb9bdc75fd9 198 SUPERFAMILY SSF46785 6 174 2.82E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09155 9690dd9a5cd8514501480cb9bdc75fd9 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 4.0E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_09155 9690dd9a5cd8514501480cb9bdc75fd9 198 SMART SM00418 9 89 1.8E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_09785 77046b48b165050ec530aaf70f81f512 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 21 87 1.9E-8 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A3L14_09785 77046b48b165050ec530aaf70f81f512 88 SUPERFAMILY SSF143011 1 84 7.06E-20 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_09785 77046b48b165050ec530aaf70f81f512 88 Gene3D G3DSA:3.30.2310.20 1 88 8.0E-28 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_10450 7a5aa5f71f0569a1bd911337f35468f0 149 Pfam PF00582 Universal stress protein family 2 149 1.7E-21 T 23-10-2018 IPR006016 UspA A3L14_10450 7a5aa5f71f0569a1bd911337f35468f0 149 Gene3D G3DSA:3.40.50.620 1 149 1.8E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_10450 7a5aa5f71f0569a1bd911337f35468f0 149 SUPERFAMILY SSF52402 2 149 1.17E-27 T 23-10-2018 A3L14_09975 971da29e53284f0ed5e559b2475b748f 178 SUPERFAMILY SSF53927 22 147 7.15E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L14_09975 971da29e53284f0ed5e559b2475b748f 178 PIRSF PIRSF006019 12 169 1.4E-56 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L14_09975 971da29e53284f0ed5e559b2475b748f 178 Gene3D G3DSA:3.40.140.10 18 167 7.5E-48 T 23-10-2018 A3L14_09975 971da29e53284f0ed5e559b2475b748f 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 2.4E-28 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L14_09975 971da29e53284f0ed5e559b2475b748f 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 PIRSF PIRSF001021 2 457 2.1E-119 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 Gene3D G3DSA:3.20.20.80 24 359 3.4E-109 T 23-10-2018 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 Pfam PF00128 Alpha amylase, catalytic domain 52 316 4.0E-11 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 Gene3D G3DSA:2.60.40.1180 360 457 1.1E-51 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 SMART SM00642 32 377 8.7E-24 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 PRINTS PR00110 Alpha-amylase signature 122 133 9.5E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 PRINTS PR00110 Alpha-amylase signature 301 313 9.5E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 PRINTS PR00110 Alpha-amylase signature 214 225 9.5E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 Pfam PF09154 Domain of unknown function (DUF1939) 386 452 2.9E-22 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 SUPERFAMILY SSF51445 29 380 7.04E-73 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_00190 a1d89ad2a8733584cb06a492ef6f8193 457 SUPERFAMILY SSF51011 384 457 3.16E-38 T 23-10-2018 A3L14_00395 73c60734094b5e0fbc6eb7e4ff5eb381 248 Gene3D G3DSA:3.40.50.300 3 246 1.4E-67 T 23-10-2018 A3L14_11400 21a864aba5d7594ed5880a24c4040126 161 SUPERFAMILY SSF143437 36 147 4.36E-17 T 23-10-2018 A3L14_11400 21a864aba5d7594ed5880a24c4040126 161 SMART SM00981 63 150 2.2E-18 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_11400 21a864aba5d7594ed5880a24c4040126 161 Gene3D G3DSA:3.30.2130.30 7 151 1.1E-13 T 23-10-2018 A3L14_11400 21a864aba5d7594ed5880a24c4040126 161 Pfam PF02926 THUMP domain 34 148 1.1E-22 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 3.6E-16 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 3.6E-16 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 3.6E-16 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 3.6E-16 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 Gene3D G3DSA:3.50.50.60 107 431 3.6E-144 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 424 2.8E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 SUPERFAMILY SSF51905 142 307 1.07E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 SUPERFAMILY SSF51905 1 191 1.01E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 9.4E-66 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 Gene3D G3DSA:3.50.50.60 2 331 3.6E-144 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 SUPERFAMILY SSF55424 316 437 3.26E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.9E-22 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.9E-22 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.9E-22 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.9E-22 T 23-10-2018 A3L14_09780 60df4e8c32a5d2e0b287dc2514d4db6e 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.9E-22 T 23-10-2018 A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 SUPERFAMILY SSF51735 8 258 7.11E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 7.1E-51 T 23-10-2018 A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 Gene3D G3DSA:3.40.50.720 2 258 1.1E-65 T 23-10-2018 A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.0E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.0E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.0E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.0E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_07620 03f38a263cde2f3f52da72bc2a7dbee5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 7.0E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_03360 4d94ea64eb8c36fe518e7c25f2a72ed7 422 Pfam PF04895 Archaeal Nre, C-terminal 297 407 5.7E-37 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A3L14_03360 4d94ea64eb8c36fe518e7c25f2a72ed7 422 Pfam PF04894 Archaeal Nre, N-terminal 20 285 6.2E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A3L14_03360 4d94ea64eb8c36fe518e7c25f2a72ed7 422 Hamap MF_02096 DNA repair protein. 1 407 39.784 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A3L14_03235 db65389371b296a86ef4b46dcada513c 189 SUPERFAMILY SSF51182 2 188 1.13E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_03235 db65389371b296a86ef4b46dcada513c 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 182 1.4E-42 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L14_03235 db65389371b296a86ef4b46dcada513c 189 Gene3D G3DSA:2.60.120.10 1 189 1.1E-74 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_03235 db65389371b296a86ef4b46dcada513c 189 PIRSF PIRSF019325 1 189 5.3E-74 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L14_11015 7ad37bc587b244a65d9b33939585639e 137 PIRSF PIRSF019240 2 136 2.3E-23 T 23-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related A3L14_11015 7ad37bc587b244a65d9b33939585639e 137 Gene3D G3DSA:2.10.260.10 10 102 7.0E-18 T 23-10-2018 A3L14_05140 d7163bf5f9819d18d3e11f38dd907edc 289 SUPERFAMILY SSF103481 48 146 2.88E-13 T 23-10-2018 A3L14_05140 d7163bf5f9819d18d3e11f38dd907edc 289 Pfam PF00892 EamA-like transporter family 153 288 2.4E-22 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_05140 d7163bf5f9819d18d3e11f38dd907edc 289 Pfam PF00892 EamA-like transporter family 6 141 1.1E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_05140 d7163bf5f9819d18d3e11f38dd907edc 289 SUPERFAMILY SSF103481 193 287 1.57E-11 T 23-10-2018 A3L14_10465 8ae6595b43d4406bbb285677d1ffdaf9 642 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 69 178 1.2E-12 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L14_10465 8ae6595b43d4406bbb285677d1ffdaf9 642 Gene3D G3DSA:3.30.230.10 32 225 3.2E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_10465 8ae6595b43d4406bbb285677d1ffdaf9 642 SUPERFAMILY SSF54211 52 230 7.59E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 5 221 40.234 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 SMART SM01133 6 219 2.3E-118 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 PIRSF PIRSF001357 3 225 2.4E-93 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 Gene3D G3DSA:3.20.20.70 2 225 2.6E-109 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 SUPERFAMILY SSF51569 4 220 2.72E-94 T 23-10-2018 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 217 2.0E-92 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_11450 82b4c3ecb0ebb56f64b38a352c49f9dd 226 Pfam PF01791 DeoC/LacD family aldolase 7 216 1.5E-23 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L14_11395 1414a685be8813cbf273beb03a285703 236 Pfam PF00881 Nitroreductase family 58 232 3.8E-36 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_11395 1414a685be8813cbf273beb03a285703 236 SUPERFAMILY SSF55469 54 235 5.68E-38 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_11395 1414a685be8813cbf273beb03a285703 236 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 73 232 9.8E-47 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain A3L14_11395 1414a685be8813cbf273beb03a285703 236 Gene3D G3DSA:3.40.109.10 32 235 2.7E-76 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 Gene3D G3DSA:1.10.10.10 1 51 5.1E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 2.0E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 Gene3D G3DSA:3.30.70.920 53 146 1.3E-21 T 23-10-2018 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 SUPERFAMILY SSF54909 61 144 3.49E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 SUPERFAMILY SSF46785 1 61 2.24E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 6.0E-18 T 23-10-2018 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 SMART SM00344 1 107 1.2E-42 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_02755 d8dd00158d8f05ffaf15e35ed3f2cbd9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05980 8b495679979933134f1513a17699c0cc 331 Gene3D G3DSA:3.40.50.150 143 331 1.1E-54 T 23-10-2018 A3L14_05980 8b495679979933134f1513a17699c0cc 331 Gene3D G3DSA:3.30.300.110 58 142 8.8E-27 T 23-10-2018 A3L14_05980 8b495679979933134f1513a17699c0cc 331 Gene3D G3DSA:3.30.70.2580 1 57 3.5E-5 T 23-10-2018 A3L14_05980 8b495679979933134f1513a17699c0cc 331 SUPERFAMILY SSF53335 72 329 2.24E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_05980 8b495679979933134f1513a17699c0cc 331 Pfam PF02475 Met-10+ like-protein 82 277 1.6E-67 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 52 109 3.0E-26 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 18 109 1.3E-34 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 SUPERFAMILY SSF50249 6 113 4.0E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 40 62 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 Pfam PF01176 Translation initiation factor 1A / IF-1 31 94 1.8E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 16 110 28.133 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 SMART SM00652 27 110 3.6E-43 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L14_06575 0b9bec3dfd8c63831c0c2916d1f109ef 121 Gene3D G3DSA:2.40.50.140 10 121 9.0E-41 T 23-10-2018 A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 Gene3D G3DSA:3.40.50.300 249 421 6.3E-14 T 23-10-2018 A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 Gene3D G3DSA:3.40.50.300 1 113 9.3E-13 T 23-10-2018 A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 PIRSF PIRSF029347 1 93 9.9E-13 T 23-10-2018 IPR014555 RecF-like A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 PIRSF PIRSF029347 261 433 1.4E-16 T 23-10-2018 IPR014555 RecF-like A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 Pfam PF13175 AAA ATPase domain 3 47 7.3E-14 T 23-10-2018 A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 237 399 5.2E-21 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_03880 7502f931cdd36fd7a08bd548af8d2424 453 SUPERFAMILY SSF52540 2 418 3.35E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 Gene3D G3DSA:3.40.50.1450 9 155 8.0E-41 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 PRINTS PR00446 Hydrogen uptake protein signature 67 77 1.2E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 PRINTS PR00446 Hydrogen uptake protein signature 13 25 1.2E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 PRINTS PR00446 Hydrogen uptake protein signature 25 36 1.2E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 152 1.6E-30 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 SUPERFAMILY SSF53163 12 156 1.96E-29 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L14_03185 437082f89a6ccc1ae02319600adf8eed 157 Pfam PF01750 Hydrogenase maturation protease 31 131 1.0E-13 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 SUPERFAMILY SSF53335 4 375 5.21E-105 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 374 6.4E-112 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 376 2.8E-94 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 Gene3D G3DSA:3.40.50.150 1 317 1.3E-101 T 23-10-2018 A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 Gene3D G3DSA:3.30.56.70 318 377 4.5E-21 T 23-10-2018 A3L14_05850 926fc499d9157f5067f1da17145dae4d 377 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 376 42.974 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 Gene3D G3DSA:3.20.20.140 55 344 1.0E-154 T 23-10-2018 A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 SUPERFAMILY SSF51556 54 347 3.97E-104 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.025 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 Pfam PF01979 Amidohydrolase family 51 397 4.4E-74 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 Gene3D G3DSA:2.30.40.10 4 416 1.0E-154 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_00160 83b867d1a3925fff0b83bf876700793b 424 SUPERFAMILY SSF51338 1 423 2.0E-38 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 SMART SM00788 3 334 7.5E-154 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 Pfam PF00709 Adenylosuccinate synthetase 148 289 3.4E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 SUPERFAMILY SSF52540 1 335 8.71E-107 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 Gene3D G3DSA:3.40.440.10 1 339 8.3E-136 T 23-10-2018 A3L14_07560 5a9037e2db6da067e259ac6d3c2d48ac 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 95.253 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L14_08230 c1e51a0b9e4e8725bb5b61aabdcaa354 237 Gene3D G3DSA:3.40.50.12500 6 237 6.9E-89 T 23-10-2018 A3L14_08230 c1e51a0b9e4e8725bb5b61aabdcaa354 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 31 215 9.9E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_08230 c1e51a0b9e4e8725bb5b61aabdcaa354 237 PIRSF PIRSF015736 1 237 6.3E-90 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A3L14_03920 7aef8c74e4b742e999b37ee6b9fa0267 95 SUPERFAMILY SSF158372 5 85 1.57E-25 T 23-10-2018 IPR036809 AF1782-like superfamily A3L14_03920 7aef8c74e4b742e999b37ee6b9fa0267 95 Gene3D G3DSA:1.20.1270.90 5 85 5.0E-25 T 23-10-2018 A3L14_03920 7aef8c74e4b742e999b37ee6b9fa0267 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 3.1E-29 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 Gene3D G3DSA:3.30.1330.10 1 155 8.7E-44 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 SUPERFAMILY SSF55326 4 155 2.27E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 6.1E-120 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 8.9E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 Gene3D G3DSA:3.90.650.10 156 338 2.1E-57 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 SUPERFAMILY SSF56042 156 332 1.36E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 PIRSF PIRSF005644 1 338 1.9E-126 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L14_03150 0065df4c5eaf8acec7bcd064ac7cf7b8 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 316 1.2E-33 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 Gene3D G3DSA:3.40.1360.10 156 385 3.5E-64 T 23-10-2018 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 Pfam PF04406 Type IIB DNA topoisomerase 83 151 2.0E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 Gene3D G3DSA:1.10.10.10 14 155 1.5E-51 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 SUPERFAMILY SSF56726 81 383 1.57E-78 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.39 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 2.6E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 2.6E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 2.6E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 2.6E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_06555 33463f655394fc72f8e30ea7f86a469f 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 2.6E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 SUPERFAMILY SSF54810 189 307 6.15E-45 T 23-10-2018 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.144 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 Pfam PF02540 NAD synthase 5 80 1.1E-6 T 23-10-2018 IPR022310 NAD/GMP synthase A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 307 2.8E-151 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 Gene3D G3DSA:3.40.50.620 2 189 2.5E-77 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 Pfam PF00958 GMP synthase C terminal domain 217 306 2.8E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 Gene3D G3DSA:3.30.300.10 190 307 9.5E-53 T 23-10-2018 A3L14_01435 41854ca86b288b6a4c711a8e54fd680f 307 SUPERFAMILY SSF52402 3 224 2.21E-54 T 23-10-2018 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 Gene3D G3DSA:3.40.50.10490 7 201 2.7E-71 T 23-10-2018 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 SUPERFAMILY SSF52313 3 192 3.53E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 3.2E-99 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.316 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 4.1E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 Pfam PF00318 Ribosomal protein S2 12 103 2.3E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02715 d8f9d50782b11803785d00a505ee04b8 201 Pfam PF00318 Ribosomal protein S2 110 174 8.2E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07575 5d212366abea420d32cecfbdaa3a6788 146 Gene3D G3DSA:1.10.287.370 1 146 1.2E-45 T 23-10-2018 IPR009053 Prefoldin A3L14_07575 5d212366abea420d32cecfbdaa3a6788 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 1 137 15.91 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L14_07575 5d212366abea420d32cecfbdaa3a6788 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 137 1.6E-36 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L14_07575 5d212366abea420d32cecfbdaa3a6788 146 Pfam PF02996 Prefoldin subunit 17 136 3.3E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L14_07575 5d212366abea420d32cecfbdaa3a6788 146 SUPERFAMILY SSF46579 7 138 1.91E-29 T 23-10-2018 A3L14_04390 f6777c2f0865a91c8e891f550021c753 443 Gene3D G3DSA:1.20.1530.20 5 425 1.3E-21 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L14_04390 f6777c2f0865a91c8e891f550021c753 443 Pfam PF00999 Sodium/hydrogen exchanger family 17 416 1.9E-55 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L14_06430 1afdd8373662fcc3df7ab2c3b937ca95 435 PIRSF PIRSF009445 1 434 3.4E-189 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L14_06430 1afdd8373662fcc3df7ab2c3b937ca95 435 Gene3D G3DSA:3.40.50.300 133 323 8.2E-8 T 23-10-2018 A3L14_06430 1afdd8373662fcc3df7ab2c3b937ca95 435 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 4 435 48.065 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L14_09995 01f050bca6fb4b5e1b52fafb0fe7328d 249 Gene3D G3DSA:3.30.70.1900 122 242 2.1E-37 T 23-10-2018 A3L14_09995 01f050bca6fb4b5e1b52fafb0fe7328d 249 Gene3D G3DSA:3.30.70.1890 1 121 4.7E-43 T 23-10-2018 A3L14_09995 01f050bca6fb4b5e1b52fafb0fe7328d 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 7.9E-43 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_09995 01f050bca6fb4b5e1b52fafb0fe7328d 249 PIRSF PIRSF005054 1 242 6.6E-63 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_09995 01f050bca6fb4b5e1b52fafb0fe7328d 249 Pfam PF01881 CRISPR associated protein Cas6 95 238 2.2E-31 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 SUPERFAMILY SSF46785 3 81 1.63E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 SUPERFAMILY SSF46785 85 152 3.34E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 5.7E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 PIRSF PIRSF019345 2 193 4.2E-46 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 Gene3D G3DSA:1.10.10.10 83 160 1.9E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 Gene3D G3DSA:1.10.10.10 2 82 1.4E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01885 7cfa19a751cc22b900f7e84d44c0f464 200 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 8.3E-32 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L14_09350 78ef1b13ca38feb15075b3e83827bebd 269 Pfam PF02535 ZIP Zinc transporter 124 264 7.7E-20 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 95.998 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 PIRSF PIRSF006413 2 228 8.9E-79 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 3.6E-64 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 Gene3D G3DSA:3.75.10.10 1 227 6.4E-79 T 23-10-2018 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 SUPERFAMILY SSF55909 3 226 7.06E-74 T 23-10-2018 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 Pfam PF01912 eIF-6 family 5 206 7.8E-69 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L14_08700 6e69209fd1d6a5b0ae2519e535796b65 228 SMART SM00654 4 206 2.4E-103 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 Gene3D G3DSA:3.90.1070.10 86 153 3.1E-72 T 23-10-2018 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 Hamap MF_01419 Phosphoglycolate phosphatase. 3 229 31.738 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 219 1.7E-73 T 23-10-2018 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 SUPERFAMILY SSF56784 1 228 6.3E-40 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 Gene3D G3DSA:3.40.50.1000 4 222 3.1E-72 T 23-10-2018 IPR023214 HAD superfamily A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 143 218 4.3E-17 T 23-10-2018 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 90 6.3E-8 T 23-10-2018 A3L14_03895 6b71e04fe5980518fea7446d320cb631 245 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 231 2.5E-69 T 23-10-2018 A3L14_08120 b632324f83a88e53fd7c4fd91360ffab 149 SUPERFAMILY SSF46785 11 134 1.69E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08120 b632324f83a88e53fd7c4fd91360ffab 149 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.5E-17 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_08120 b632324f83a88e53fd7c4fd91360ffab 149 Gene3D G3DSA:1.10.10.10 1 102 2.9E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 38.097 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 2.0E-158 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Gene3D G3DSA:2.30.30.300 170 213 6.9E-109 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Gene3D G3DSA:1.10.10.860 271 318 2.3E-23 T 23-10-2018 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 SUPERFAMILY SSF48163 323 523 1.09E-49 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Gene3D G3DSA:1.10.10.770 319 433 4.7E-37 T 23-10-2018 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Gene3D G3DSA:1.10.10.350 434 526 9.3E-26 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 SUPERFAMILY SSF52374 3 319 3.49E-67 T 23-10-2018 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 2.8E-138 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L14_10050 31f5242a9d7ff4a735ea27146e874e99 526 Gene3D G3DSA:3.40.50.620 4 270 6.9E-109 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_02800 73bba220706c3aa85395370800f35d5e 267 Pfam PF01048 Phosphorylase superfamily 3 246 1.4E-54 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L14_02800 73bba220706c3aa85395370800f35d5e 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.797 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L14_02800 73bba220706c3aa85395370800f35d5e 267 Gene3D G3DSA:3.40.50.1580 1 266 7.7E-101 T 23-10-2018 A3L14_02800 73bba220706c3aa85395370800f35d5e 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L14_02800 73bba220706c3aa85395370800f35d5e 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 4.6E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L14_02800 73bba220706c3aa85395370800f35d5e 267 SUPERFAMILY SSF53167 1 264 4.45E-96 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L14_04290 e4e6bb495e2057ddad59c228a10bdc5c 120 Pfam PF03874 RNA polymerase Rpb4 11 118 8.7E-6 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A3L14_04290 e4e6bb495e2057ddad59c228a10bdc5c 120 Gene3D G3DSA:1.10.150.80 55 120 7.8E-27 T 23-10-2018 A3L14_04290 e4e6bb495e2057ddad59c228a10bdc5c 120 Gene3D G3DSA:1.10.287.420 1 54 1.1E-35 T 23-10-2018 A3L14_04290 e4e6bb495e2057ddad59c228a10bdc5c 120 PIRSF PIRSF005053 1 120 2.4E-29 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A3L14_04290 e4e6bb495e2057ddad59c228a10bdc5c 120 SUPERFAMILY SSF47819 1 119 1.53E-23 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A3L14_10685 382188f169b03b8d0947ef8e0a495b93 279 SUPERFAMILY SSF103481 38 133 1.57E-14 T 23-10-2018 A3L14_10685 382188f169b03b8d0947ef8e0a495b93 279 SUPERFAMILY SSF103481 176 272 2.22E-7 T 23-10-2018 A3L14_10685 382188f169b03b8d0947ef8e0a495b93 279 Pfam PF00892 EamA-like transporter family 144 271 5.0E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_10685 382188f169b03b8d0947ef8e0a495b93 279 Pfam PF00892 EamA-like transporter family 6 130 1.4E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_07990 a75a13733c8e9b5994df06a55b2ccbd5 108 Gene3D G3DSA:3.40.50.1010 10 107 1.2E-11 T 23-10-2018 A3L14_07990 a75a13733c8e9b5994df06a55b2ccbd5 108 SUPERFAMILY SSF88723 3 98 3.08E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05325 7bc6c8523afe5f7f4fa8b7a7c5c340a0 281 SUPERFAMILY SSF52518 19 259 5.18E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L14_05325 7bc6c8523afe5f7f4fa8b7a7c5c340a0 281 Gene3D G3DSA:3.40.50.970 88 248 7.3E-28 T 23-10-2018 A3L14_05325 7bc6c8523afe5f7f4fa8b7a7c5c340a0 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 3.5E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 2.0E-81 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 Gene3D G3DSA:3.40.50.720 1 171 2.5E-64 T 23-10-2018 A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 SUPERFAMILY SSF51735 1 149 2.56E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 3.1E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 Gene3D G3DSA:1.10.1040.10 172 296 2.8E-42 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 1.7E-36 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A3L14_10520 b75a9f1e816b0460d7a92411ad20e76d 302 SUPERFAMILY SSF48179 172 295 1.84E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L14_03750 bcedb2c3445c39d33601cf5ff911733e 238 Gene3D G3DSA:1.10.3210.30 1 209 8.0E-59 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A3L14_03750 bcedb2c3445c39d33601cf5ff911733e 238 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 12 172 5.8E-15 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 Gene3D G3DSA:1.10.1660.10 2 51 4.8E-10 T 23-10-2018 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 SUPERFAMILY SSF53041 56 188 1.29E-24 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 SUPERFAMILY SSF46955 2 50 2.44E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 Pfam PF00239 Resolvase, N terminal domain 57 189 7.3E-26 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 Gene3D G3DSA:3.40.50.1390 54 154 1.4E-28 T 23-10-2018 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 SMART SM00857 57 180 4.3E-27 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 Pfam PF12728 Helix-turn-helix domain 3 51 1.8E-14 T 23-10-2018 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A3L14_01780 cd3dee0fd3c0938464e8da9fa6315ba9 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 46 1.1E-14 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A3L14_00825 fd8d03eb83dbd1803b37303c964bea9d 294 Pfam PF00892 EamA-like transporter family 3 137 6.7E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_00825 fd8d03eb83dbd1803b37303c964bea9d 294 Pfam PF00892 EamA-like transporter family 146 273 1.0E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_00825 fd8d03eb83dbd1803b37303c964bea9d 294 SUPERFAMILY SSF103481 180 277 4.05E-19 T 23-10-2018 A3L14_00825 fd8d03eb83dbd1803b37303c964bea9d 294 SUPERFAMILY SSF103481 38 140 2.09E-13 T 23-10-2018 A3L14_03515 4d216725e8bad8c4df51d8e582a58a50 250 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 228 3.9E-18 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L14_03515 4d216725e8bad8c4df51d8e582a58a50 250 SUPERFAMILY SSF51695 8 232 4.97E-39 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L14_03515 4d216725e8bad8c4df51d8e582a58a50 250 Gene3D G3DSA:3.20.20.190 3 240 1.9E-44 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L14_07325 a18b3b3f450324c12f9e4ea3fb540012 116 SUPERFAMILY SSF117916 26 89 2.49E-11 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L14_07325 a18b3b3f450324c12f9e4ea3fb540012 116 Gene3D G3DSA:3.30.300.130 22 108 2.0E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L14_07325 a18b3b3f450324c12f9e4ea3fb540012 116 Pfam PF01883 Iron-sulfur cluster assembly protein 27 87 2.6E-10 T 23-10-2018 IPR002744 MIP18 family-like A3L14_04925 0b7a40bc167fcd23641c79847af6305c 377 PIRSF PIRSF005357 1 346 1.5E-115 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L14_04925 0b7a40bc167fcd23641c79847af6305c 377 SUPERFAMILY SSF53756 1 321 4.93E-25 T 23-10-2018 A3L14_04925 0b7a40bc167fcd23641c79847af6305c 377 Pfam PF04007 Protein of unknown function (DUF354) 1 318 1.2E-96 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L14_02680 22104cf2d7864167da117c16c266d8e7 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.911 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A3L14_02680 22104cf2d7864167da117c16c266d8e7 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 1.1E-17 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L14_02680 22104cf2d7864167da117c16c266d8e7 121 SUPERFAMILY SSF52080 6 120 4.06E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L14_02680 22104cf2d7864167da117c16c266d8e7 121 Gene3D G3DSA:3.100.10.10 6 121 1.1E-40 T 23-10-2018 A3L14_02680 22104cf2d7864167da117c16c266d8e7 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 1.8E-26 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 SUPERFAMILY SSF54211 9 212 2.99E-52 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 SUPERFAMILY SSF55666 184 268 5.33E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 Pfam PF03725 3' exoribonuclease family, domain 2 189 253 2.8E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 45.093 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A3L14_02200 6dcec591d71ab08cdecc15418d042d89 269 Gene3D G3DSA:3.30.230.70 1 268 1.6E-86 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L14_03065 cec87a575d7dc30387d8f51c6d26cbc5 222 SUPERFAMILY SSF53271 13 217 1.08E-55 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_03065 cec87a575d7dc30387d8f51c6d26cbc5 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 3.4E-49 T 23-10-2018 A3L14_03065 cec87a575d7dc30387d8f51c6d26cbc5 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 3.8E-74 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L14_03065 cec87a575d7dc30387d8f51c6d26cbc5 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 39.616 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L14_03065 cec87a575d7dc30387d8f51c6d26cbc5 222 Gene3D G3DSA:3.40.50.2020 1 218 4.1E-57 T 23-10-2018 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.515 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PIRSF PIRSF000724 1 407 4.9E-129 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 1.6E-64 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 Gene3D G3DSA:3.40.50.1260 10 397 6.7E-137 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 Pfam PF00162 Phosphoglycerate kinase 5 389 1.1E-105 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 Gene3D G3DSA:3.40.50.1260 189 390 6.7E-137 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 SUPERFAMILY SSF53748 2 398 5.54E-115 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_08100 ba5ef5a5df02e1821b7a10313307f7ad 409 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_09825 fbaafc0c240456f6140ed229cfd1f625 388 SUPERFAMILY SSF54373 225 318 1.7E-8 T 23-10-2018 A3L14_09825 fbaafc0c240456f6140ed229cfd1f625 388 SUPERFAMILY SSF51905 2 378 4.66E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09825 fbaafc0c240456f6140ed229cfd1f625 388 Gene3D G3DSA:3.50.50.60 4 359 3.9E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09825 fbaafc0c240456f6140ed229cfd1f625 388 Gene3D G3DSA:3.30.9.10 82 317 3.9E-112 T 23-10-2018 A3L14_09825 fbaafc0c240456f6140ed229cfd1f625 388 Pfam PF01266 FAD dependent oxidoreductase 3 353 2.1E-67 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L14_09195 df0671a3fa294cb86ef6fc3c832a5710 282 SUPERFAMILY SSF53613 1 265 2.18E-34 T 23-10-2018 IPR029056 Ribokinase-like A3L14_09195 df0671a3fa294cb86ef6fc3c832a5710 282 Gene3D G3DSA:3.40.1190.20 1 275 5.0E-89 T 23-10-2018 IPR029056 Ribokinase-like A3L14_11190 84969f1f2e84d680187474ef89a68fe6 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.3E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_11190 84969f1f2e84d680187474ef89a68fe6 75 SUPERFAMILY SSF54909 1 74 9.52E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_11190 84969f1f2e84d680187474ef89a68fe6 75 Gene3D G3DSA:3.30.70.920 1 74 8.7E-27 T 23-10-2018 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 SUPERFAMILY SSF55729 489 643 8.54E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Gene3D G3DSA:3.40.50.11040 25 250 2.8E-11 T 23-10-2018 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 806 48.615 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Pfam PF13718 GNAT acetyltransferase 2 497 614 6.9E-34 T 23-10-2018 IPR000182 GNAT domain A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Pfam PF08351 Domain of unknown function (DUF1726) 128 220 1.8E-32 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Gene3D G3DSA:3.40.50.12320 280 447 3.3E-34 T 23-10-2018 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Gene3D G3DSA:3.40.630.30 455 661 1.4E-55 T 23-10-2018 A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 SUPERFAMILY SSF52540 226 396 2.0E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07965 989fc7f7a20394828d6928981f7f383f 810 Pfam PF05127 Helicase 284 457 1.7E-55 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A3L14_03120 87541e3a5e0e4f00fa02e1cb4c0a8129 414 SUPERFAMILY SSF103473 37 411 5.89E-34 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_03120 87541e3a5e0e4f00fa02e1cb4c0a8129 414 Pfam PF07690 Major Facilitator Superfamily 43 381 2.3E-23 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_03120 87541e3a5e0e4f00fa02e1cb4c0a8129 414 Gene3D G3DSA:1.20.1250.20 28 413 7.4E-33 T 23-10-2018 A3L14_01000 5102ac95f96556b8b71165e1e0ab013a 175 Gene3D G3DSA:3.30.70.20 31 142 2.0E-15 T 23-10-2018 A3L14_01000 5102ac95f96556b8b71165e1e0ab013a 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_01000 5102ac95f96556b8b71165e1e0ab013a 175 Pfam PF13247 4Fe-4S dicluster domain 54 132 7.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_01000 5102ac95f96556b8b71165e1e0ab013a 175 Pfam PF12800 4Fe-4S binding domain 15 29 0.026 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_01000 5102ac95f96556b8b71165e1e0ab013a 175 SUPERFAMILY SSF54862 8 140 1.42E-31 T 23-10-2018 A3L14_07855 6ef6db4f9f5e2c2420100205c840f2ec 316 SUPERFAMILY SSF46785 262 315 1.04E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07855 6ef6db4f9f5e2c2420100205c840f2ec 316 Pfam PF12802 MarR family 263 305 8.9E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L14_07855 6ef6db4f9f5e2c2420100205c840f2ec 316 Gene3D G3DSA:1.10.10.10 240 316 1.4E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 SUPERFAMILY SSF53383 6 427 6.19E-133 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 Gene3D G3DSA:3.40.640.10 38 280 3.1E-84 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 Pfam PF00464 Serine hydroxymethyltransferase 11 390 1.4E-80 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 Gene3D G3DSA:3.90.1150.10 281 426 3.4E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.261 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L14_06850 8a28e037187e6afbf61eb0b09b531307 429 PIRSF PIRSF000412 3 425 5.8E-145 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 SMART SM00881 12 111 2.0E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 SUPERFAMILY SSF52210 143 304 1.83E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 Gene3D G3DSA:3.40.50.720 6 140 4.9E-43 T 23-10-2018 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 Pfam PF13380 CoA binding domain 16 145 2.3E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 4.1E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 Gene3D G3DSA:3.40.50.261 142 306 5.0E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 SUPERFAMILY SSF51735 10 141 1.73E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 Gene3D G3DSA:3.40.50.261 308 469 2.0E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_08165 8b51db18f66825036e51885ac97b7cea 472 SUPERFAMILY SSF52210 311 468 8.11E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 Gene3D G3DSA:3.40.50.300 162 357 3.2E-57 T 23-10-2018 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 326 5.3E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 2.3E-24 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 Gene3D G3DSA:1.20.120.1190 1 161 5.2E-54 T 23-10-2018 A3L14_03950 17812639dd5958e5fa81e794d4fd5f03 359 SUPERFAMILY SSF52540 168 352 7.92E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00135 a1147e1c773b8dfea89984610642370c 223 Pfam PF01939 Endonuclease NucS 2 220 5.9E-90 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L14_00135 a1147e1c773b8dfea89984610642370c 223 Gene3D G3DSA:2.70.180.20 1 97 1.0E-36 T 23-10-2018 A3L14_00135 a1147e1c773b8dfea89984610642370c 223 Gene3D G3DSA:3.40.1350.10 98 209 1.4E-42 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L14_00135 a1147e1c773b8dfea89984610642370c 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 214 38.771 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L14_00440 b1dbb551a3afd69c66dd52f9d3b16acd 360 Gene3D G3DSA:3.40.50.2000 183 341 2.3E-137 T 23-10-2018 A3L14_00440 b1dbb551a3afd69c66dd52f9d3b16acd 360 SUPERFAMILY SSF53756 1 354 1.18E-118 T 23-10-2018 A3L14_00440 b1dbb551a3afd69c66dd52f9d3b16acd 360 Gene3D G3DSA:3.40.50.2000 6 351 2.3E-137 T 23-10-2018 A3L14_00440 b1dbb551a3afd69c66dd52f9d3b16acd 360 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 354 1.9E-118 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L14_00440 b1dbb551a3afd69c66dd52f9d3b16acd 360 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 354 6.2E-115 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L14_08630 b8f467ee7a4e995224e4b94048018a4d 108 Pfam PF05239 PRC-barrel domain 2 82 2.4E-13 T 23-10-2018 IPR027275 PRC-barrel domain A3L14_08630 b8f467ee7a4e995224e4b94048018a4d 108 SUPERFAMILY SSF50346 4 79 1.67E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L14_08630 b8f467ee7a4e995224e4b94048018a4d 108 Gene3D G3DSA:2.30.30.240 3 82 1.5E-5 T 23-10-2018 A3L14_01075 9ea68206f0a231f6a08421dbb81e6adc 319 Pfam PF07760 Protein of unknown function (DUF1616) 3 315 5.5E-94 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A3L14_01075 9ea68206f0a231f6a08421dbb81e6adc 319 PIRSF PIRSF018671 1 319 1.5E-120 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A3L14_04305 a37853537824c36b580d26113bd3b0f7 180 SUPERFAMILY SSF47240 26 174 4.54E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_04305 a37853537824c36b580d26113bd3b0f7 180 Gene3D G3DSA:1.20.1260.10 19 174 1.5E-26 T 23-10-2018 IPR012347 Ferritin-like A3L14_04305 a37853537824c36b580d26113bd3b0f7 180 Pfam PF02915 Rubrerythrin 41 170 1.4E-9 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_09020 7d42001886cb1547342e2c6bbed7f098 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 1.5E-41 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_09020 7d42001886cb1547342e2c6bbed7f098 134 Gene3D G3DSA:2.60.120.460 1 133 3.3E-49 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L14_09020 7d42001886cb1547342e2c6bbed7f098 134 PIRSF PIRSF004681 2 133 9.1E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_09020 7d42001886cb1547342e2c6bbed7f098 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 131 5.4E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L14_09020 7d42001886cb1547342e2c6bbed7f098 134 SUPERFAMILY SSF111038 2 131 4.71E-41 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 Gene3D G3DSA:2.40.30.40 70 164 3.1E-112 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 SUPERFAMILY SSF101821 67 178 1.39E-26 T 23-10-2018 A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 SUPERFAMILY SSF53187 2 334 6.53E-49 T 23-10-2018 A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 Gene3D G3DSA:3.40.630.10 11 332 3.1E-112 T 23-10-2018 A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 Pfam PF05343 M42 glutamyl aminopeptidase 48 327 1.5E-70 T 23-10-2018 IPR008007 Peptidase M42 A3L14_05700 a1192ffef83fef3eb0f50161f0eb79b3 338 PIRSF PIRSF001123 1 336 4.0E-37 T 23-10-2018 IPR008007 Peptidase M42 A3L14_03025 9c9a7b508713f36ec2ca8d505fd035d0 107 SUPERFAMILY SSF81324 8 105 4.58E-17 T 23-10-2018 A3L14_03025 9c9a7b508713f36ec2ca8d505fd035d0 107 Pfam PF07885 Ion channel 26 95 1.2E-11 T 23-10-2018 IPR013099 Potassium channel domain A3L14_03025 9c9a7b508713f36ec2ca8d505fd035d0 107 Gene3D G3DSA:1.10.287.70 6 107 1.0E-14 T 23-10-2018 A3L14_02515 263413d51d4451978f83c05472aec5a0 98 PIRSF PIRSF037511 5 97 1.9E-25 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L14_02515 263413d51d4451978f83c05472aec5a0 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.534 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A3L14_02515 263413d51d4451978f83c05472aec5a0 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 97 9.3E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L14_02515 263413d51d4451978f83c05472aec5a0 98 SUPERFAMILY SSF55159 5 90 5.75E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A3L14_02515 263413d51d4451978f83c05472aec5a0 98 Gene3D G3DSA:3.30.780.10 20 98 1.4E-28 T 23-10-2018 A3L14_02515 263413d51d4451978f83c05472aec5a0 98 Pfam PF01253 Translation initiation factor SUI1 20 89 2.6E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A3L14_07445 3e48facbd85d4a0511fba7827783942f 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 48.509 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L14_07445 3e48facbd85d4a0511fba7827783942f 252 Pfam PF00977 Histidine biosynthesis protein 5 233 3.8E-90 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A3L14_07445 3e48facbd85d4a0511fba7827783942f 252 Gene3D G3DSA:3.20.20.70 1 252 4.3E-109 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_07445 3e48facbd85d4a0511fba7827783942f 252 SUPERFAMILY SSF51366 1 249 6.99E-86 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L14_07445 3e48facbd85d4a0511fba7827783942f 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 2.1E-110 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A3L14_02120 82d4fbe8418dcbdeb54f2d5e8c1d8bb5 227 Gene3D G3DSA:3.30.420.440 1 227 5.9E-105 T 23-10-2018 A3L14_02120 82d4fbe8418dcbdeb54f2d5e8c1d8bb5 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 2.5E-130 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A3L14_01040 be99788f5c0c54fe90d7e04223010072 153 Gene3D G3DSA:3.40.50.2020 1 153 9.4E-55 T 23-10-2018 A3L14_01040 be99788f5c0c54fe90d7e04223010072 153 Pfam PF00156 Phosphoribosyl transferase domain 13 149 1.2E-28 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_01040 be99788f5c0c54fe90d7e04223010072 153 SUPERFAMILY SSF53271 2 145 4.06E-36 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 Gene3D G3DSA:2.40.50.140 2 71 7.5E-16 T 23-10-2018 A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 6.7E-84 T 23-10-2018 A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 SUPERFAMILY SSF50249 4 57 2.0E-8 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 246 414 1.2E-21 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 Gene3D G3DSA:3.40.1350.30 112 257 1.5E-116 T 23-10-2018 A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 Gene3D G3DSA:3.40.50.150 73 410 1.5E-116 T 23-10-2018 A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L14_10815 dd40fbd1dcb2bda263e0c28353689aca 417 SUPERFAMILY SSF53335 59 413 3.35E-72 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.1 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 Gene3D G3DSA:2.40.50.1000 1 111 3.6E-38 T 23-10-2018 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 1.0E-32 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 3.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 Pfam PF00366 Ribosomal protein S17 35 102 5.7E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 5.7E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 SUPERFAMILY SSF50249 29 109 1.17E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_02525 05c7f964d304d667f0aa3d073066900a 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05560 8f6e34a68c59b65a8f9a29c9af7ce443 72 SUPERFAMILY SSF89447 1 47 1.06E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_05560 8f6e34a68c59b65a8f9a29c9af7ce443 72 Pfam PF02381 MraZ protein, putative antitoxin-like 7 42 2.3E-5 T 23-10-2018 IPR020603 MraZ domain A3L14_01100 9212f144fd1048cad4da4b699040729d 309 Gene3D G3DSA:3.40.50.300 2 200 6.7E-53 T 23-10-2018 A3L14_01100 9212f144fd1048cad4da4b699040729d 309 SUPERFAMILY SSF52540 4 280 1.1E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01100 9212f144fd1048cad4da4b699040729d 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 4.5E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L14_01100 9212f144fd1048cad4da4b699040729d 309 PIRSF PIRSF002849 1 309 1.3E-130 T 23-10-2018 A3L14_01100 9212f144fd1048cad4da4b699040729d 309 SMART SM00382 34 175 1.2E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01100 9212f144fd1048cad4da4b699040729d 309 Gene3D G3DSA:1.10.8.300 201 305 1.3E-33 T 23-10-2018 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Gene3D G3DSA:3.40.1030.10 152 412 8.4E-101 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 SUPERFAMILY SSF52418 155 404 3.66E-68 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 1.5E-14 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 6.1E-226 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Gene3D G3DSA:1.20.970.10 84 151 1.7E-23 T 23-10-2018 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 SUPERFAMILY SSF47648 86 153 9.03E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Gene3D G3DSA:2.40.40.20 1 83 2.2E-38 T 23-10-2018 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 SMART SM00941 424 491 1.8E-23 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.543 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 4.6E-243 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Gene3D G3DSA:3.90.1170.30 413 493 4.0E-28 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 6.9E-13 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 PIRSF PIRSF000478 84 502 4.5E-121 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 2.2E-13 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_08440 f0026603ab7d113c916aee86143e6c49 503 SUPERFAMILY SSF54680 412 495 1.57E-17 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 3.5E-15 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 Gene3D G3DSA:3.30.1390.20 5 143 1.2E-54 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 4.9E-62 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 SUPERFAMILY SSF55129 5 155 2.35E-48 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 80.96 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L14_02585 75d83e7502cac5eeb048ef377cf9aae7 155 Gene3D G3DSA:1.10.15.30 60 114 1.2E-54 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A3L14_01645 14e628beb41834000e40a1ebc56be06b 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 1.5E-58 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L14_01645 14e628beb41834000e40a1ebc56be06b 264 Gene3D G3DSA:3.60.110.10 1 263 2.2E-102 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L14_01645 14e628beb41834000e40a1ebc56be06b 264 SUPERFAMILY SSF56317 1 264 2.22E-74 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L14_11300 401e0788e9ce39d3b39ec31b123ab969 141 Gene3D G3DSA:3.30.70.3270 23 141 4.4E-22 T 23-10-2018 A3L14_11300 401e0788e9ce39d3b39ec31b123ab969 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_11300 401e0788e9ce39d3b39ec31b123ab969 141 Pfam PF12838 4Fe-4S dicluster domain 45 91 4.0E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_11300 401e0788e9ce39d3b39ec31b123ab969 141 SUPERFAMILY SSF54862 27 108 4.84E-22 T 23-10-2018 A3L14_11300 401e0788e9ce39d3b39ec31b123ab969 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07165 efa63e2c971872cf7712e1628989a667 207 PRINTS PR00363 Cytochrome B5 signature 154 168 4.8E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A3L14_07165 efa63e2c971872cf7712e1628989a667 207 PRINTS PR00363 Cytochrome B5 signature 144 154 4.8E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A3L14_07165 efa63e2c971872cf7712e1628989a667 207 PRINTS PR00363 Cytochrome B5 signature 181 193 4.8E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A3L14_07165 efa63e2c971872cf7712e1628989a667 207 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 123 193 1.3E-19 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A3L14_07165 efa63e2c971872cf7712e1628989a667 207 SUPERFAMILY SSF55856 120 196 2.49E-24 T 23-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily A3L14_07165 efa63e2c971872cf7712e1628989a667 207 Pfam PF14358 Domain of unknown function (DUF4405) 14 65 1.4E-5 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A3L14_07165 efa63e2c971872cf7712e1628989a667 207 Gene3D G3DSA:3.10.120.10 115 195 5.3E-27 T 23-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily A3L14_07165 efa63e2c971872cf7712e1628989a667 207 SMART SM01117 122 194 3.5E-22 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A3L14_06440 dcea914025b97487119e9448dc5bdc15 292 SMART SM00849 15 200 4.4E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_06440 dcea914025b97487119e9448dc5bdc15 292 Gene3D G3DSA:3.60.15.10 1 216 3.1E-27 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_06440 dcea914025b97487119e9448dc5bdc15 292 SUPERFAMILY SSF56281 4 277 1.4E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_06440 dcea914025b97487119e9448dc5bdc15 292 Pfam PF00753 Metallo-beta-lactamase superfamily 16 189 1.6E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_07250 6838b0ea1ecbad9599a2eca2ea5c7d46 434 SUPERFAMILY SSF52833 23 171 6.64E-14 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L14_07250 6838b0ea1ecbad9599a2eca2ea5c7d46 434 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 210 416 4.8E-9 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A3L14_07250 6838b0ea1ecbad9599a2eca2ea5c7d46 434 Gene3D G3DSA:3.40.30.10 22 173 6.1E-12 T 23-10-2018 A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 83 143 7.9E-12 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 SUPERFAMILY SSF81296 85 176 2.0E-16 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 Gene3D G3DSA:3.20.20.80 278 683 3.3E-123 T 23-10-2018 A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 SMART SM00642 292 681 5.3E-105 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 SUPERFAMILY SSF51445 254 688 5.29E-107 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 Gene3D G3DSA:2.60.40.10 72 174 2.0E-19 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_05815 771f4d6096a985dd8e5c931b3acc3308 762 Pfam PF00128 Alpha amylase, catalytic domain 346 651 8.4E-67 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 SUPERFAMILY SSF52283 1 132 8.51E-33 T 23-10-2018 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 318 7.1E-32 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 Gene3D G3DSA:3.40.50.720 16 318 2.0E-110 T 23-10-2018 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 SUPERFAMILY SSF51735 100 287 1.16E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 7.1E-54 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L14_05230 e9ec900cb043c76d68a300b3cd3e39fa 333 Gene3D G3DSA:3.40.50.720 95 286 2.0E-110 T 23-10-2018 A3L14_01140 fdc4197aa1137b1f6bb5fc45a0746bd7 164 Pfam PF01943 Polysaccharide biosynthesis protein 12 140 3.2E-15 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L14_04405 322f08a21bbc5c2c2438433bac213f72 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 1.4E-7 T 23-10-2018 A3L14_04405 322f08a21bbc5c2c2438433bac213f72 233 Gene3D G3DSA:1.10.150.240 15 92 4.9E-36 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L14_04405 322f08a21bbc5c2c2438433bac213f72 233 Gene3D G3DSA:3.40.50.1000 93 230 2.9E-26 T 23-10-2018 IPR023214 HAD superfamily A3L14_04405 322f08a21bbc5c2c2438433bac213f72 233 SUPERFAMILY SSF56784 5 218 8.91E-25 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_09700 0f159350753f642eb892a2aa17e5c7bb 386 Gene3D G3DSA:3.30.9.10 88 315 3.5E-142 T 23-10-2018 A3L14_09700 0f159350753f642eb892a2aa17e5c7bb 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 2.0E-73 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L14_09700 0f159350753f642eb892a2aa17e5c7bb 386 SUPERFAMILY SSF51905 11 376 2.07E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09700 0f159350753f642eb892a2aa17e5c7bb 386 Gene3D G3DSA:3.50.50.60 12 359 3.5E-142 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09700 0f159350753f642eb892a2aa17e5c7bb 386 SUPERFAMILY SSF54373 224 316 7.46E-10 T 23-10-2018 A3L14_01095 18fb70263a023c53042ef23e6cf4af9d 342 Pfam PF14258 Domain of unknown function (DUF4350) 36 105 5.2E-9 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 A3L14_01095 18fb70263a023c53042ef23e6cf4af9d 342 SUPERFAMILY SSF52317 66 228 2.75E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_03780 15b27f6c96d1b76a5be6cb5efa3aeaab 253 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 43 238 7.7E-50 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_03780 15b27f6c96d1b76a5be6cb5efa3aeaab 253 Gene3D G3DSA:3.30.70.1900 123 241 1.4E-37 T 23-10-2018 A3L14_03780 15b27f6c96d1b76a5be6cb5efa3aeaab 253 PIRSF PIRSF005054 1 243 1.9E-68 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_03780 15b27f6c96d1b76a5be6cb5efa3aeaab 253 Pfam PF01881 CRISPR associated protein Cas6 95 239 1.3E-34 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L14_03780 15b27f6c96d1b76a5be6cb5efa3aeaab 253 Gene3D G3DSA:3.30.70.1890 1 122 1.3E-39 T 23-10-2018 A3L14_01525 cf0942ba7d77d6af574b7a2301ad0968 51 SMART SM01402 4 46 2.8E-24 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L14_01525 cf0942ba7d77d6af574b7a2301ad0968 51 Gene3D G3DSA:2.20.25.660 2 49 2.2E-19 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L14_01525 cf0942ba7d77d6af574b7a2301ad0968 51 Pfam PF01599 Ribosomal protein S27a 5 46 4.4E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L14_01525 cf0942ba7d77d6af574b7a2301ad0968 51 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 4 49 19.74 T 23-10-2018 IPR022845 Ribosomal protein S27ae A3L14_01525 cf0942ba7d77d6af574b7a2301ad0968 51 SUPERFAMILY SSF57829 4 50 3.11E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_03540 3d5ab69e1255d71c886c5aaa5ebdb60b 235 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 68 4.1E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_03540 3d5ab69e1255d71c886c5aaa5ebdb60b 235 Gene3D G3DSA:3.40.120.10 3 78 3.6E-6 T 23-10-2018 A3L14_03540 3d5ab69e1255d71c886c5aaa5ebdb60b 235 SUPERFAMILY SSF53738 8 76 8.63E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L14_05970 e84a3d635e316c28e4b12b67bcc0566b 455 SUPERFAMILY SSF111283 2 450 4.97E-98 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_05970 e84a3d635e316c28e4b12b67bcc0566b 455 Gene3D G3DSA:3.30.2290.10 1 216 8.9E-17 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_05970 e84a3d635e316c28e4b12b67bcc0566b 455 PIRSF PIRSF004919 1 455 3.4E-157 T 23-10-2018 IPR025502 TldD A3L14_05970 e84a3d635e316c28e4b12b67bcc0566b 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 7.6E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_10560 c2eaaff0eaf2e207d6c3d99d10733988 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 106 4.4E-20 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L14_10560 c2eaaff0eaf2e207d6c3d99d10733988 119 SUPERFAMILY SSF69118 12 109 1.13E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L14_10560 c2eaaff0eaf2e207d6c3d99d10733988 119 Gene3D G3DSA:1.20.1290.10 3 118 2.9E-29 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L14_10560 c2eaaff0eaf2e207d6c3d99d10733988 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 44 86 7.9E-13 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L14_01135 434b6dd82f32b8d9428fe51d36760e79 509 Pfam PF01943 Polysaccharide biosynthesis protein 12 288 1.3E-22 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L14_01135 434b6dd82f32b8d9428fe51d36760e79 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 477 1.6E-21 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L14_03105 4646b0f4ab21601844804e5fdcfd5a36 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 6.1E-32 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A3L14_03105 4646b0f4ab21601844804e5fdcfd5a36 99 Gene3D G3DSA:3.30.1860.10 1 97 2.0E-34 T 23-10-2018 A3L14_10745 2e1397a070a2ac691fd63fb5bb104a4b 280 Gene3D G3DSA:3.90.226.10 63 272 1.7E-23 T 23-10-2018 A3L14_10745 2e1397a070a2ac691fd63fb5bb104a4b 280 Pfam PF01972 Serine dehydrogenase proteinase 6 276 4.0E-148 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A3L14_10745 2e1397a070a2ac691fd63fb5bb104a4b 280 SUPERFAMILY SSF52096 66 241 1.23E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 SUPERFAMILY SSF48452 41 234 1.23E-20 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 Pfam PF13424 Tetratricopeptide repeat 133 201 1.2E-8 T 23-10-2018 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 Pfam PF13424 Tetratricopeptide repeat 58 122 3.6E-7 T 23-10-2018 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 SMART SM00028 55 88 240.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 SMART SM00028 174 207 70.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 SMART SM00028 93 126 0.0025 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 SMART SM00028 134 167 33.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L14_01255 f34ff3f706dcb83dcf36bf9bf6271dad 341 Gene3D G3DSA:1.25.40.10 49 244 3.6E-26 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_02470 6128b4710e1c3ca0e1c4a59edfeaf85b 256 SUPERFAMILY SSF75217 4 254 1.14E-46 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_02470 6128b4710e1c3ca0e1c4a59edfeaf85b 256 Gene3D G3DSA:2.40.50.140 91 156 3.1E-76 T 23-10-2018 A3L14_02470 6128b4710e1c3ca0e1c4a59edfeaf85b 256 SUPERFAMILY SSF50249 91 156 2.23E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_02470 6128b4710e1c3ca0e1c4a59edfeaf85b 256 Pfam PF02598 Putative RNA methyltransferase 5 249 5.4E-50 T 23-10-2018 IPR003750 Putative RNA methyltransferase A3L14_02470 6128b4710e1c3ca0e1c4a59edfeaf85b 256 Gene3D G3DSA:3.40.1280.10 5 252 3.1E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L14_00465 3ee17cb8779e9b1142068d33a8446f56 338 Gene3D G3DSA:3.90.25.30 171 273 2.3E-110 T 23-10-2018 A3L14_00465 3ee17cb8779e9b1142068d33a8446f56 338 Pfam PF02719 Polysaccharide biosynthesis protein 11 293 3.4E-91 T 23-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A3L14_00465 3ee17cb8779e9b1142068d33a8446f56 338 Gene3D G3DSA:3.40.50.720 8 295 2.3E-110 T 23-10-2018 A3L14_00465 3ee17cb8779e9b1142068d33a8446f56 338 SUPERFAMILY SSF51735 8 244 6.28E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_05545 267d3144c15c25a4e914f4b7c8b769f0 234 SUPERFAMILY SSF52540 5 227 9.14E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05545 267d3144c15c25a4e914f4b7c8b769f0 234 Gene3D G3DSA:3.40.50.300 4 230 8.3E-57 T 23-10-2018 A3L14_05545 267d3144c15c25a4e914f4b7c8b769f0 234 Pfam PF06745 KaiC 6 228 4.5E-51 T 23-10-2018 IPR014774 KaiC-like domain A3L14_05545 267d3144c15c25a4e914f4b7c8b769f0 234 PRINTS PR01874 DNA repair protein radA signature 57 74 2.7E-8 T 23-10-2018 A3L14_05545 267d3144c15c25a4e914f4b7c8b769f0 234 PRINTS PR01874 DNA repair protein radA signature 15 43 2.7E-8 T 23-10-2018 A3L14_05365 aa560b2ac465282c454d96f9b8cf8c97 324 SMART SM00729 17 247 1.1E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_05365 aa560b2ac465282c454d96f9b8cf8c97 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 7.6E-124 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L14_05365 aa560b2ac465282c454d96f9b8cf8c97 324 SUPERFAMILY SSF102114 16 255 4.45E-16 T 23-10-2018 A3L14_05365 aa560b2ac465282c454d96f9b8cf8c97 324 PIRSF PIRSF004954 1 319 1.2E-100 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L14_05365 aa560b2ac465282c454d96f9b8cf8c97 324 Pfam PF04055 Radical SAM superfamily 33 178 6.5E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_03745 cd47e73c350abbf49797ae57d4a9e9c9 347 Pfam PF09703 CRISPR-associated protein (Cas_Csa4) 6 340 1.1E-88 T 23-10-2018 IPR010184 CRISPR-associated protein, MJ0385 A3L14_03745 cd47e73c350abbf49797ae57d4a9e9c9 347 TIGRFAM TIGR01914 cas_Csa4: CRISPR-associated protein Cas8a2/Csa4, subtype I-A/APERN 2 341 5.6E-109 T 23-10-2018 IPR010184 CRISPR-associated protein, MJ0385 A3L14_06735 e1db2b3114f10d47336c68d8c075a54f 123 TIGRFAM TIGR00494 crcB: protein CrcB 7 121 1.7E-28 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L14_06735 e1db2b3114f10d47336c68d8c075a54f 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.569 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L14_06735 e1db2b3114f10d47336c68d8c075a54f 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 7.0E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L14_09830 de62bc327cc74729ea9c63d59b1f5271 90 Gene3D G3DSA:1.10.10.1100 2 67 3.4E-21 T 23-10-2018 A3L14_09830 de62bc327cc74729ea9c63d59b1f5271 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 2.5E-13 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 1.7E-69 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 Pfam PF08423 Rad51 2 218 8.0E-31 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 SUPERFAMILY SSF52540 2 220 8.11E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 Gene3D G3DSA:3.40.50.300 7 220 1.7E-58 T 23-10-2018 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 PRINTS PR01874 DNA repair protein radA signature 11 39 4.2E-7 T 23-10-2018 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 PRINTS PR01874 DNA repair protein radA signature 190 216 4.2E-7 T 23-10-2018 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 PIRSF PIRSF003336 1 220 7.4E-97 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L14_10120 32131a3f996c787dc5541c9183dd3958 221 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 37.101 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L14_04175 c3d53de8ab8d81ec31d48440ca66f404 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 265 2.1E-71 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A3L14_04175 c3d53de8ab8d81ec31d48440ca66f404 272 SUPERFAMILY SSF51717 6 269 1.31E-79 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_04175 c3d53de8ab8d81ec31d48440ca66f404 272 Pfam PF00809 Pterin binding enzyme 14 252 2.2E-60 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_04175 c3d53de8ab8d81ec31d48440ca66f404 272 Gene3D G3DSA:3.20.20.20 1 271 1.1E-88 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 Gene3D G3DSA:3.40.50.10880 132 284 3.8E-60 T 23-10-2018 A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 SUPERFAMILY SSF111321 1 282 1.22E-78 T 23-10-2018 IPR036075 AF1104-like superfamily A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 Gene3D G3DSA:1.10.8.380 1 68 2.6E-27 T 23-10-2018 A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 Pfam PF01937 Protein of unknown function DUF89 4 276 4.9E-48 T 23-10-2018 IPR002791 Domain of unknown function DUF89 A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 Gene3D G3DSA:1.10.285.20 69 129 2.0E-10 T 23-10-2018 A3L14_02785 57cb2523ce05bd92355c87cda2191cc8 284 PIRSF PIRSF006593 1 284 7.5E-91 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 Pfam PF00571 CBS domain 10 60 3.7E-10 T 23-10-2018 IPR000644 CBS domain A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 Pfam PF00571 CBS domain 71 123 5.8E-13 T 23-10-2018 IPR000644 CBS domain A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 Gene3D G3DSA:3.10.580.10 1 135 5.3E-44 T 23-10-2018 A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 SMART SM00116 78 125 1.7E-7 T 23-10-2018 IPR000644 CBS domain A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 SMART SM00116 14 61 5.4E-10 T 23-10-2018 IPR000644 CBS domain A3L14_06415 c41453a251971353dc2b816eeb0c6b24 135 SUPERFAMILY SSF54631 7 127 5.68E-31 T 23-10-2018 A3L14_03525 3f70b17c516d9e57a0aa4a028e1f0d8f 434 Pfam PF07690 Major Facilitator Superfamily 253 421 4.2E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_03525 3f70b17c516d9e57a0aa4a028e1f0d8f 434 SUPERFAMILY SSF103473 1 427 6.67E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_03525 3f70b17c516d9e57a0aa4a028e1f0d8f 434 Gene3D G3DSA:1.20.1250.20 280 429 1.0E-15 T 23-10-2018 A3L14_03525 3f70b17c516d9e57a0aa4a028e1f0d8f 434 Gene3D G3DSA:1.20.1250.20 6 279 4.0E-17 T 23-10-2018 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 SMART SM00846 3 141 3.2E-18 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 Gene3D G3DSA:3.30.360.10 140 301 8.8E-147 T 23-10-2018 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 187.816 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 8.7E-180 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 PIRSF PIRSF000149 1 318 1.9E-85 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 Gene3D G3DSA:3.40.50.720 3 331 8.8E-147 T 23-10-2018 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 SUPERFAMILY SSF55347 140 301 1.21E-51 T 23-10-2018 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 108 5.5E-13 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 7.3E-31 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L14_05775 9cce7bfd8095cf7dd1f7a881ac402eba 334 SUPERFAMILY SSF51735 3 158 1.23E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09500 9c31f4dbd5d41aadc590552275a2935f 334 Gene3D G3DSA:1.10.10.10 266 330 4.9E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09500 9c31f4dbd5d41aadc590552275a2935f 334 Pfam PF04122 Putative cell wall binding repeat 2 114 192 5.5E-7 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L14_09500 9c31f4dbd5d41aadc590552275a2935f 334 SUPERFAMILY SSF46785 266 330 1.85E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09500 9c31f4dbd5d41aadc590552275a2935f 334 SUPERFAMILY SSF53686 116 212 6.72E-5 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 3.3E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 3.3E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 3.3E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 3.3E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 SUPERFAMILY SSF46785 41 120 3.44E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 2.2E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 SMART SM00418 44 121 3.4E-26 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_05055 059b1590f297b09778e9e1531a43bbf7 125 Gene3D G3DSA:1.10.10.10 11 123 2.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04845 d6953989fb45ad8eeb7c3f905dcd92ac 309 Pfam PF00146 NADH dehydrogenase 8 306 2.4E-53 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11440 90e1b872be3e48a1dd8afa79453e0dbe 198 Pfam PF07155 ECF-type riboflavin transporter, S component 38 189 1.1E-37 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A3L14_11440 90e1b872be3e48a1dd8afa79453e0dbe 198 Gene3D G3DSA:1.10.1760.20 35 193 4.0E-47 T 23-10-2018 A3L14_04580 9c6407e36de4917fea7d76c4fb2c4dd9 241 SUPERFAMILY SSF50249 134 223 2.42E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_04580 9c6407e36de4917fea7d76c4fb2c4dd9 241 Gene3D G3DSA:2.40.50.140 125 241 3.7E-35 T 23-10-2018 A3L14_04580 9c6407e36de4917fea7d76c4fb2c4dd9 241 Gene3D G3DSA:1.20.1440.150 1 124 2.6E-58 T 23-10-2018 A3L14_04580 9c6407e36de4917fea7d76c4fb2c4dd9 241 Pfam PF01588 Putative tRNA binding domain 138 224 2.5E-18 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 Gene3D G3DSA:3.50.50.60 5 333 2.3E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.4E-26 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 3.4E-26 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.4E-26 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 3.4E-26 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.4E-26 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 297 3.5E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 SUPERFAMILY SSF55424 318 442 1.89E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 424 5.8E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 SUPERFAMILY SSF51905 1 309 2.69E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 Gene3D G3DSA:3.50.50.60 107 424 2.3E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 6.9E-20 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 6.9E-20 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.9E-20 T 23-10-2018 A3L14_02805 bb9942e336a05782839d4045848d0bb8 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 6.9E-20 T 23-10-2018 A3L14_05830 bf4b79aef97aaa6931a0143c3c4bbaae 456 PIRSF PIRSF006603 6 456 8.8E-111 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05830 bf4b79aef97aaa6931a0143c3c4bbaae 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 419 2.8E-127 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05830 bf4b79aef97aaa6931a0143c3c4bbaae 456 Pfam PF01554 MatE 17 177 1.1E-39 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05830 bf4b79aef97aaa6931a0143c3c4bbaae 456 Pfam PF01554 MatE 241 407 3.7E-34 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 Gene3D G3DSA:3.40.630.50 1 186 1.5E-68 T 23-10-2018 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 70 269 8.5E-66 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 SUPERFAMILY SSF142535 1 270 1.44E-84 T 23-10-2018 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 Gene3D G3DSA:3.40.50.10700 187 272 3.0E-31 T 23-10-2018 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 PIRSF PIRSF016210 1 272 1.1E-79 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L14_03640 3c50786f4bd2eee2330a097cb1b58071 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 34.264 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 Gene3D G3DSA:3.30.479.30 50 181 5.7E-50 T 23-10-2018 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 155 173 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 131 154 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 29 51 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 111 128 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 174 195 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 PRINTS PR00721 Stomatin signature 76 97 3.8E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 SMART SM00244 22 179 3.4E-71 T 23-10-2018 IPR001107 Band 7 domain A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 Pfam PF01145 SPFH domain / Band 7 family 26 206 1.7E-41 T 23-10-2018 IPR001107 Band 7 domain A3L14_07865 7b697232773cc9b1894ee808fa77a2b1 321 SUPERFAMILY SSF117892 53 186 7.19E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L14_03975 6fb203254e19e209fd7863272cef0327 391 SUPERFAMILY SSF54631 127 261 6.22E-35 T 23-10-2018 A3L14_03975 6fb203254e19e209fd7863272cef0327 391 SMART SM00116 139 187 1.4E-10 T 23-10-2018 IPR000644 CBS domain A3L14_03975 6fb203254e19e209fd7863272cef0327 391 SMART SM00116 75 123 0.2 T 23-10-2018 IPR000644 CBS domain A3L14_03975 6fb203254e19e209fd7863272cef0327 391 SMART SM00116 217 265 1.5E-8 T 23-10-2018 IPR000644 CBS domain A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Gene3D G3DSA:3.10.580.10 2 124 6.1E-17 T 23-10-2018 A3L14_03975 6fb203254e19e209fd7863272cef0327 391 PIRSF PIRSF036983 2 391 1.0E-138 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A3L14_03975 6fb203254e19e209fd7863272cef0327 391 SUPERFAMILY SSF54631 4 122 9.1E-18 T 23-10-2018 A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Gene3D G3DSA:3.10.580.10 125 206 6.3E-19 T 23-10-2018 A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Gene3D G3DSA:3.10.580.10 207 302 1.9E-14 T 23-10-2018 A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Pfam PF00571 CBS domain 70 123 9.0E-6 T 23-10-2018 IPR000644 CBS domain A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Pfam PF00571 CBS domain 132 183 2.5E-17 T 23-10-2018 IPR000644 CBS domain A3L14_03975 6fb203254e19e209fd7863272cef0327 391 Pfam PF00571 CBS domain 211 261 1.9E-11 T 23-10-2018 IPR000644 CBS domain A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 SUPERFAMILY SSF100966 9 110 5.36E-27 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 Gene3D G3DSA:3.30.70.3150 41 131 3.8E-31 T 23-10-2018 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 10 142 9.1E-51 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 SMART SM00653 30 137 3.1E-57 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 Pfam PF01873 Domain found in IF2B/IF5 24 136 1.0E-35 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 SUPERFAMILY SSF75689 107 142 6.02E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_02265 d9f5eec1a9f5cd521ba561f2ff1bb7ae 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 9 143 33.087 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 9 378 6.2E-169 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 Gene3D G3DSA:3.90.1150.10 5 374 4.1E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 SUPERFAMILY SSF53383 2 383 1.28E-102 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.773 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 72 331 3.6E-34 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A3L14_00490 ad93879609ade44cf291b9b5bb756c4e 385 Gene3D G3DSA:3.40.640.10 40 290 4.1E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_00870 7529cbb4b85376fca261ee8983a3df7b 249 SUPERFAMILY SSF52540 7 244 1.81E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00870 7529cbb4b85376fca261ee8983a3df7b 249 Pfam PF06745 KaiC 10 246 6.0E-77 T 23-10-2018 IPR014774 KaiC-like domain A3L14_00870 7529cbb4b85376fca261ee8983a3df7b 249 Gene3D G3DSA:3.40.50.300 2 249 2.4E-74 T 23-10-2018 A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 Pfam PF00117 Glutamine amidotransferase class-I 300 525 3.5E-58 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 Gene3D G3DSA:3.40.50.880 284 531 1.4E-106 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 Pfam PF06418 CTP synthase N-terminus 3 265 1.1E-127 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.187 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 SUPERFAMILY SSF52317 288 529 1.25E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 SUPERFAMILY SSF52540 2 265 6.84E-122 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 5.6E-253 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L14_03935 c7b8725f517a191dd234c3977e543c41 532 Gene3D G3DSA:3.40.50.300 1 283 5.5E-140 T 23-10-2018 A3L14_08325 d4f791ce589a142a884e160e90c672c5 204 Gene3D G3DSA:1.20.1540.10 3 198 4.2E-37 T 23-10-2018 IPR035952 Rhomboid-like superfamily A3L14_08325 d4f791ce589a142a884e160e90c672c5 204 Pfam PF01694 Rhomboid family 56 191 2.2E-30 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A3L14_08325 d4f791ce589a142a884e160e90c672c5 204 SUPERFAMILY SSF144091 10 193 2.09E-38 T 23-10-2018 A3L14_10435 1ec5bf6ceb56a66751a042b7b583f1eb 453 Pfam PF01523 Putative modulator of DNA gyrase 19 307 1.1E-65 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_10435 1ec5bf6ceb56a66751a042b7b583f1eb 453 Gene3D G3DSA:3.30.2290.10 1 195 2.0E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_10435 1ec5bf6ceb56a66751a042b7b583f1eb 453 SUPERFAMILY SSF111283 3 447 6.15E-117 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_10435 1ec5bf6ceb56a66751a042b7b583f1eb 453 PIRSF PIRSF004919 1 453 1.7E-162 T 23-10-2018 IPR025502 TldD A3L14_00420 0b2cede4391121c5ddafcff388e2241e 367 PIRSF PIRSF000390 1 367 9.7E-131 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L14_00420 0b2cede4391121c5ddafcff388e2241e 367 Gene3D G3DSA:3.40.640.10 1 240 1.3E-106 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_00420 0b2cede4391121c5ddafcff388e2241e 367 Gene3D G3DSA:3.90.1150.10 241 367 3.3E-43 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_00420 0b2cede4391121c5ddafcff388e2241e 367 SUPERFAMILY SSF53383 3 365 2.18E-132 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_00420 0b2cede4391121c5ddafcff388e2241e 367 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 362 5.1E-139 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A3L14_05745 30c472711bde9cee615a716265dce148 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 1.7E-48 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L14_05745 30c472711bde9cee615a716265dce148 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 1.5E-58 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L14_05745 30c472711bde9cee615a716265dce148 171 SUPERFAMILY SSF89028 2 165 2.94E-50 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L14_05745 30c472711bde9cee615a716265dce148 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 165 1.0E-68 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L14_05745 30c472711bde9cee615a716265dce148 171 Gene3D G3DSA:1.20.1200.10 25 171 4.4E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L14_04160 497b3ed033a47d19a785eda329412775 335 SUPERFAMILY SSF52096 88 282 1.68E-37 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L14_04160 497b3ed033a47d19a785eda329412775 335 Gene3D G3DSA:3.90.226.10 93 289 8.8E-56 T 23-10-2018 A3L14_04160 497b3ed033a47d19a785eda329412775 335 Gene3D G3DSA:3.40.1750.20 188 254 8.8E-56 T 23-10-2018 A3L14_04160 497b3ed033a47d19a785eda329412775 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 90 294 2.1E-69 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A3L14_04160 497b3ed033a47d19a785eda329412775 335 Pfam PF01343 Peptidase family S49 151 297 2.9E-41 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 SUPERFAMILY SSF51905 1 326 4.23E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 Gene3D G3DSA:3.30.9.10 69 356 4.9E-108 T 23-10-2018 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 Gene3D G3DSA:3.50.50.60 3 338 4.9E-108 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 393 39.411 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 Pfam PF01494 FAD binding domain 3 319 9.1E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 301 5.4E-75 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.6E-10 T 23-10-2018 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 5.6E-10 T 23-10-2018 A3L14_03705 421866c04c2d13818ad00c87f5996c97 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 5.6E-10 T 23-10-2018 A3L14_07400 1aca66e3e3391c9789331a7fe4ca2084 137 SMART SM00670 1 105 9.9E-9 T 23-10-2018 IPR002716 PIN domain A3L14_07400 1aca66e3e3391c9789331a7fe4ca2084 137 SUPERFAMILY SSF88723 1 107 1.69E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_07400 1aca66e3e3391c9789331a7fe4ca2084 137 Pfam PF13470 PIN domain 2 101 4.7E-11 T 23-10-2018 IPR002716 PIN domain A3L14_07400 1aca66e3e3391c9789331a7fe4ca2084 137 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 106 5.4E-16 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A3L14_07000 8ed1f72b7702b23813be6bfd1c8ec407 243 Gene3D G3DSA:3.40.50.150 8 236 6.7E-27 T 23-10-2018 A3L14_07000 8ed1f72b7702b23813be6bfd1c8ec407 243 SUPERFAMILY SSF53335 28 227 6.91E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_07000 8ed1f72b7702b23813be6bfd1c8ec407 243 Pfam PF13847 Methyltransferase domain 69 185 7.3E-13 T 23-10-2018 IPR025714 Methyltransferase domain A3L14_06755 4b5db06f359a045289788ec32b43c759 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 82 6.8E-15 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L14_06755 4b5db06f359a045289788ec32b43c759 97 SUPERFAMILY SSF101386 1 79 1.13E-21 T 23-10-2018 A3L14_06755 4b5db06f359a045289788ec32b43c759 97 Gene3D G3DSA:1.10.287.1080 1 79 7.8E-29 T 23-10-2018 A3L14_06375 9fe21c2e69cf76587447bfc7b30161c2 270 Gene3D G3DSA:1.20.1260.10 53 225 9.7E-68 T 23-10-2018 IPR012347 Ferritin-like A3L14_06375 9fe21c2e69cf76587447bfc7b30161c2 270 SUPERFAMILY SSF47240 58 198 2.23E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_06375 9fe21c2e69cf76587447bfc7b30161c2 270 Pfam PF09968 Uncharacterized protein domain (DUF2202) 58 216 3.5E-66 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 7.6E-52 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 Gene3D G3DSA:3.40.50.1860 102 211 1.2E-73 T 23-10-2018 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 Gene3D G3DSA:3.40.50.1860 4 215 1.2E-73 T 23-10-2018 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 SUPERFAMILY SSF53681 1 114 1.55E-27 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 2.8E-53 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L14_06750 c31c48502230910d3706f7811ee929d3 227 SUPERFAMILY SSF53681 116 224 9.81E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L14_00585 887508cf2e3fc7918a7c1f6746fb6116 437 Pfam PF07282 Putative transposase DNA-binding domain 319 388 1.2E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_00585 887508cf2e3fc7918a7c1f6746fb6116 437 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 271 346 3.2E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_00585 887508cf2e3fc7918a7c1f6746fb6116 437 Pfam PF01385 Probable transposase 176 299 9.9E-37 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_02065 511b93b6789a0ba2c74c0fd86f48fa0e 392 SUPERFAMILY SSF103473 12 390 1.44E-56 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_02065 511b93b6789a0ba2c74c0fd86f48fa0e 392 Pfam PF07690 Major Facilitator Superfamily 19 254 2.8E-24 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_02065 511b93b6789a0ba2c74c0fd86f48fa0e 392 Gene3D G3DSA:1.20.1250.20 211 392 3.7E-20 T 23-10-2018 A3L14_02065 511b93b6789a0ba2c74c0fd86f48fa0e 392 Gene3D G3DSA:1.20.1250.20 12 203 5.9E-24 T 23-10-2018 A3L14_01735 53a1ecc9c3986210913f009d46863e43 553 Gene3D G3DSA:1.25.10.10 1 249 2.3E-86 T 23-10-2018 IPR011989 Armadillo-like helical A3L14_01735 53a1ecc9c3986210913f009d46863e43 553 SUPERFAMILY SSF48371 11 550 4.85E-29 T 23-10-2018 IPR016024 Armadillo-type fold A3L14_01735 53a1ecc9c3986210913f009d46863e43 553 Gene3D G3DSA:1.25.10.10 330 552 1.0E-10 T 23-10-2018 IPR011989 Armadillo-like helical A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 223 248 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 9.3E-17 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L14_10455 0dd7a281b87868235d5c59600a91eda1 428 Pfam PF03600 Citrate transporter 18 368 5.8E-53 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 Pfam PF01037 Lrp/AsnC ligand binding domain 79 128 1.5E-6 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 Gene3D G3DSA:3.30.70.920 56 148 1.8E-11 T 23-10-2018 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 SUPERFAMILY SSF46785 4 62 5.07E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 SMART SM00344 4 112 1.7E-33 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 Gene3D G3DSA:1.10.10.10 1 55 2.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 3.4E-15 T 23-10-2018 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 SUPERFAMILY SSF54909 66 148 4.02E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_08050 99eb9b7adb77af87cfb90f4759fbdf8f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05755 277903a5ae0fb4afc4d00f7872b57b0c 275 Pfam PF01008 Initiation factor 2 subunit family 41 271 3.6E-49 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L14_05755 277903a5ae0fb4afc4d00f7872b57b0c 275 SUPERFAMILY SSF100950 4 272 1.5E-66 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L14_05755 277903a5ae0fb4afc4d00f7872b57b0c 275 Gene3D G3DSA:3.40.50.10470 96 275 2.1E-62 T 23-10-2018 A3L14_05755 277903a5ae0fb4afc4d00f7872b57b0c 275 Gene3D G3DSA:1.20.120.420 1 95 4.9E-30 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L14_07840 1eb1fd54d28c795a58f9c73824168927 204 SUPERFAMILY SSF75689 4 38 3.01E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_07840 1eb1fd54d28c795a58f9c73824168927 204 PIRSF PIRSF015877 1 199 4.5E-66 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A3L14_07840 1eb1fd54d28c795a58f9c73824168927 204 Pfam PF01873 Domain found in IF2B/IF5 2 34 4.0E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L14_09035 29c3d09874ea32e63941f96590f597c6 366 Gene3D G3DSA:3.40.50.150 171 354 1.3E-25 T 23-10-2018 A3L14_09035 29c3d09874ea32e63941f96590f597c6 366 SUPERFAMILY SSF53335 172 340 1.0E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_09035 29c3d09874ea32e63941f96590f597c6 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 7.0E-12 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 SUPERFAMILY SSF52980 337 403 1.36E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 SUPERFAMILY SSF52540 3 239 1.96E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 Pfam PF01022 Bacterial regulatory protein, arsR family 240 281 1.3E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 SUPERFAMILY SSF46785 226 348 4.34E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 Gene3D G3DSA:3.40.50.300 3 164 1.1E-28 T 23-10-2018 A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 1.5E-18 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_07010 66d074e1764154cc32dc17fc9439d064 452 Pfam PF03008 Archaea bacterial proteins of unknown function 307 398 7.8E-29 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 4.7E-141 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 408 1.7E-166 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 2.9E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 SUPERFAMILY SSF56542 4 398 4.71E-94 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 Gene3D G3DSA:3.90.770.10 75 395 3.2E-134 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 Gene3D G3DSA:1.10.3270.10 1 74 1.5E-6 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 SUPERFAMILY SSF55035 129 244 8.24E-40 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_04240 0a7c4ba4462402539d34923a7af726cc 408 Gene3D G3DSA:3.30.70.420 129 244 3.2E-134 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L14_00560 88384c41c252d12e9d94b3f2a33aeafa 380 Gene3D G3DSA:1.20.1530.20 1 379 7.0E-98 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L14_00560 88384c41c252d12e9d94b3f2a33aeafa 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 7.1E-68 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L14_03670 69132b11872582a08e559a2155acea18 402 SUPERFAMILY SSF53743 1 281 3.14E-38 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L14_07475 8f3a3aaf193c6c8cb621ebbb82f5701a 277 SUPERFAMILY SSF56219 11 248 7.33E-41 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L14_07475 8f3a3aaf193c6c8cb621ebbb82f5701a 277 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 14 242 2.4E-21 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A3L14_07475 8f3a3aaf193c6c8cb621ebbb82f5701a 277 Gene3D G3DSA:3.60.10.10 10 249 8.9E-50 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 SUPERFAMILY SSF63562 3 55 6.02E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.895 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 PIRSF PIRSF000778 1 57 3.7E-22 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 Gene3D G3DSA:3.90.940.50 1 57 8.0E-28 T 23-10-2018 A3L14_02705 165886a6b356013c6f0e816273ec73ff 57 Pfam PF01192 RNA polymerase Rpb6 5 51 1.7E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_03090 1d296b6ab50afd0b55fef6ce8c70e4b6 819 SUPERFAMILY SSF48239 518 779 2.2E-9 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_03090 1d296b6ab50afd0b55fef6ce8c70e4b6 819 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 216 4.1E-13 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L14_03090 1d296b6ab50afd0b55fef6ce8c70e4b6 819 Gene3D G3DSA:3.40.50.12610 377 492 5.4E-7 T 23-10-2018 A3L14_10610 3f0d51bc85b35faf0582f59a604a0a83 300 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 32 282 5.0E-96 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L14_10610 3f0d51bc85b35faf0582f59a604a0a83 300 SUPERFAMILY SSF52540 22 267 7.29E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10610 3f0d51bc85b35faf0582f59a604a0a83 300 Hamap MF_02040 Iron-sulfur cluster carrier protein. 21 283 37.203 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L14_10610 3f0d51bc85b35faf0582f59a604a0a83 300 ProSitePatterns PS01215 Mrp family signature. 147 163 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A3L14_10610 3f0d51bc85b35faf0582f59a604a0a83 300 Gene3D G3DSA:3.40.50.300 18 282 3.0E-82 T 23-10-2018 A3L14_07755 16ced7895d54dc27148dd833839b9a74 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 4.4E-67 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A3L14_07755 16ced7895d54dc27148dd833839b9a74 252 PIRSF PIRSF005902 1 252 4.3E-57 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L14_07755 16ced7895d54dc27148dd833839b9a74 252 Gene3D G3DSA:3.20.20.140 1 251 4.4E-61 T 23-10-2018 A3L14_07755 16ced7895d54dc27148dd833839b9a74 252 Pfam PF01026 TatD related DNase 2 248 1.5E-55 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L14_07755 16ced7895d54dc27148dd833839b9a74 252 SUPERFAMILY SSF51556 1 250 5.28E-55 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_07120 6ab789675a56219cbe396c7b5bf3b9c2 71 Pfam PF04945 YHS domain 3 47 7.5E-20 T 23-10-2018 IPR007029 YHS domain A3L14_07120 6ab789675a56219cbe396c7b5bf3b9c2 71 SMART SM00746 4 41 1.0E-11 T 23-10-2018 IPR011017 TRASH domain A3L14_07120 6ab789675a56219cbe396c7b5bf3b9c2 71 SUPERFAMILY SSF47240 3 47 5.95E-10 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07120 6ab789675a56219cbe396c7b5bf3b9c2 71 Gene3D G3DSA:1.10.620.20 1 66 2.3E-12 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A3L14_07225 34793c891d3292339e9b9f40a9122809 320 Pfam PF00899 ThiF family 6 224 1.5E-45 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L14_07225 34793c891d3292339e9b9f40a9122809 320 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 253 317 1.9E-6 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_07225 34793c891d3292339e9b9f40a9122809 320 Gene3D G3DSA:3.30.310.10 255 317 5.1E-6 T 23-10-2018 IPR012295 TBP domain superfamily A3L14_07225 34793c891d3292339e9b9f40a9122809 320 SUPERFAMILY SSF55945 249 316 1.11E-5 T 23-10-2018 A3L14_07225 34793c891d3292339e9b9f40a9122809 320 Gene3D G3DSA:3.40.50.720 2 233 4.1E-58 T 23-10-2018 A3L14_07225 34793c891d3292339e9b9f40a9122809 320 SUPERFAMILY SSF69572 5 232 5.76E-65 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L14_00790 5d519a7b0e87dcd40b1515100da07210 829 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 54 349 1.1E-17 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L14_00790 5d519a7b0e87dcd40b1515100da07210 829 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 800 829 5.0E-4 T 23-10-2018 A3L14_00790 5d519a7b0e87dcd40b1515100da07210 829 SUPERFAMILY SSF53850 8 358 4.89E-23 T 23-10-2018 A3L14_00790 5d519a7b0e87dcd40b1515100da07210 829 Gene3D G3DSA:3.10.105.10 177 415 1.1E-14 T 23-10-2018 A3L14_10280 a3b0bc75629e81a67b3a5e88d93da435 448 Gene3D G3DSA:3.40.50.300 211 304 1.5E-7 T 23-10-2018 A3L14_10280 a3b0bc75629e81a67b3a5e88d93da435 448 Gene3D G3DSA:3.40.50.720 3 132 5.9E-9 T 23-10-2018 A3L14_10280 a3b0bc75629e81a67b3a5e88d93da435 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 4.2E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A3L14_10280 a3b0bc75629e81a67b3a5e88d93da435 448 SUPERFAMILY SSF52540 125 295 7.65E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10135 85b4e51d6f42ef1947c9dce9fd905f49 128 SMART SM00670 3 117 8.7E-4 T 23-10-2018 IPR002716 PIN domain A3L14_10135 85b4e51d6f42ef1947c9dce9fd905f49 128 SUPERFAMILY SSF88723 1 117 9.25E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_10135 85b4e51d6f42ef1947c9dce9fd905f49 128 Pfam PF01850 PIN domain 3 117 6.8E-16 T 23-10-2018 IPR002716 PIN domain A3L14_10135 85b4e51d6f42ef1947c9dce9fd905f49 128 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 126 11.117 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_10135 85b4e51d6f42ef1947c9dce9fd905f49 128 Gene3D G3DSA:3.40.50.1010 2 127 3.3E-14 T 23-10-2018 A3L14_04825 b40b3a31020e9996a8b5317bcf293064 218 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_04825 b40b3a31020e9996a8b5317bcf293064 218 Pfam PF12838 4Fe-4S dicluster domain 61 115 4.7E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_04825 b40b3a31020e9996a8b5317bcf293064 218 SUPERFAMILY SSF54862 23 120 8.48E-22 T 23-10-2018 A3L14_04825 b40b3a31020e9996a8b5317bcf293064 218 Gene3D G3DSA:3.30.70.3270 40 157 2.7E-23 T 23-10-2018 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 Gene3D G3DSA:3.30.1330.30 1 123 7.7E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.212 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 2.1E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 3.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 7.6E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L14_07835 4aad0e78bd46c0999d733ab3bb701c9e 123 SUPERFAMILY SSF55315 4 120 5.6E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L14_10205 50117af618f0b7d71067ea3bc307c343 446 Pfam PF00149 Calcineurin-like phosphoesterase 1 217 1.3E-15 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_10205 50117af618f0b7d71067ea3bc307c343 446 Gene3D G3DSA:3.30.110.80 238 334 1.0E-122 T 23-10-2018 A3L14_10205 50117af618f0b7d71067ea3bc307c343 446 SUPERFAMILY SSF56300 1 337 9.32E-61 T 23-10-2018 A3L14_10205 50117af618f0b7d71067ea3bc307c343 446 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 416 24.432 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L14_10205 50117af618f0b7d71067ea3bc307c343 446 Gene3D G3DSA:3.60.21.10 1 280 1.0E-122 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_10215 2f8a00de6a65d37752356ebf517b11e6 442 PIRSF PIRSF018871 5 442 2.6E-121 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like A3L14_10215 2f8a00de6a65d37752356ebf517b11e6 442 SMART SM00933 43 407 2.6E-21 T 23-10-2018 IPR018977 NurA domain A3L14_10215 2f8a00de6a65d37752356ebf517b11e6 442 Pfam PF09376 NurA domain 44 407 6.5E-63 T 23-10-2018 IPR018977 NurA domain A3L14_07205 e9a53382f6befe926f18ec9c428063af 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 29 464 1.7E-190 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A3L14_07205 e9a53382f6befe926f18ec9c428063af 475 SUPERFAMILY SSF101960 39 468 3.01E-125 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L14_07205 e9a53382f6befe926f18ec9c428063af 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 2.5E-65 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L14_07150 ecc6670d279916da8f5a25505e1a33e1 188 Pfam PF03358 NADPH-dependent FMN reductase 1 135 7.2E-28 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A3L14_07150 ecc6670d279916da8f5a25505e1a33e1 188 Gene3D G3DSA:3.40.50.360 1 188 2.0E-41 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L14_07150 ecc6670d279916da8f5a25505e1a33e1 188 SUPERFAMILY SSF52218 1 168 4.33E-35 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 PRINTS PR00112 Acylphosphatase signature 26 51 7.6E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 PRINTS PR00112 Acylphosphatase signature 5 20 7.6E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 Pfam PF00708 Acylphosphatase 7 88 9.4E-29 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 SUPERFAMILY SSF54975 2 89 3.05E-32 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L14_10660 9ad4427b4a20292d8a7b27bf3cdf8fb9 91 Gene3D G3DSA:3.30.70.100 1 91 3.9E-38 T 23-10-2018 A3L14_09635 a45b9f1a47f5ef8511f10184aa001a48 93 PIRSF PIRSF004604 1 93 6.0E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_09635 a45b9f1a47f5ef8511f10184aa001a48 93 Gene3D G3DSA:3.30.2320.10 1 93 1.7E-27 T 23-10-2018 A3L14_09635 a45b9f1a47f5ef8511f10184aa001a48 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 92 2.5E-39 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_09635 a45b9f1a47f5ef8511f10184aa001a48 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 2.0E-25 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_09635 a45b9f1a47f5ef8511f10184aa001a48 93 SUPERFAMILY SSF111057 1 92 2.09E-31 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L14_06055 3991258e9c4203e74f9d3254b9faf2a8 141 Gene3D G3DSA:1.10.3760.10 2 139 2.5E-13 T 23-10-2018 A3L14_06055 3991258e9c4203e74f9d3254b9faf2a8 141 Pfam PF04608 Phosphatidylglycerophosphatase A 15 134 1.8E-10 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A3L14_06055 3991258e9c4203e74f9d3254b9faf2a8 141 SUPERFAMILY SSF101307 3 139 1.07E-35 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A3L14_06055 3991258e9c4203e74f9d3254b9faf2a8 141 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 9 135 3.7E-53 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 188 2.1E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 SUPERFAMILY SSF56784 1 217 7.13E-45 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 Gene3D G3DSA:1.10.150.240 17 86 1.7E-35 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 184 8.7E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 Gene3D G3DSA:3.40.50.1000 6 192 1.7E-35 T 23-10-2018 IPR023214 HAD superfamily A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 5.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 5.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 5.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_05655 97500d886aa1b9a5c79677d2497bcd24 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 190 7.1E-27 T 23-10-2018 A3L14_09145 8d8034d7d33838edb35eb9bee25eff5b 139 Gene3D G3DSA:2.60.120.630 1 139 4.4E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily A3L14_09145 8d8034d7d33838edb35eb9bee25eff5b 139 Pfam PF04027 Domain of unknown function (DUF371) 6 136 4.5E-51 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 Pfam PF00013 KH domain 142 189 4.8E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 Pfam PF00013 KH domain 39 86 2.1E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 215 1.9E-68 T 23-10-2018 IPR019964 KH domain protein, archaea A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 Gene3D G3DSA:3.30.1370.10 118 222 6.7E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 Gene3D G3DSA:3.30.1370.10 35 117 1.4E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 SUPERFAMILY SSF54791 40 114 5.18E-13 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 SUPERFAMILY SSF54791 136 204 5.55E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 SMART SM00322 126 193 6.7E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_06565 e89d0dd9384d154c1c6a6c4726d3b4b3 232 SMART SM00322 35 105 9.4E-11 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L14_03070 977c4dfd628dddd3b1ee15557dd4cb0c 484 Pfam PF01554 MatE 28 188 7.2E-32 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03070 977c4dfd628dddd3b1ee15557dd4cb0c 484 Pfam PF01554 MatE 253 414 5.0E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03070 977c4dfd628dddd3b1ee15557dd4cb0c 484 PIRSF PIRSF006603 2 479 9.9E-156 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_03070 977c4dfd628dddd3b1ee15557dd4cb0c 484 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 419 1.8E-73 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 Pfam PF01637 ATPase domain predominantly from Archaea 15 247 9.9E-17 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 Gene3D G3DSA:1.10.8.60 206 283 2.7E-24 T 23-10-2018 A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 Gene3D G3DSA:3.40.50.300 1 204 1.0E-41 T 23-10-2018 A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 SUPERFAMILY SSF52540 2 277 3.47E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 Gene3D G3DSA:1.10.10.10 288 362 1.5E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_05640 6d372624be0a94e4201698b1db1e55ac 362 SUPERFAMILY SSF46785 286 360 1.11E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 2.6E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 47.818 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 2.0E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 Gene3D G3DSA:3.30.160.770 12 122 3.8E-37 T 23-10-2018 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 SUPERFAMILY SSF54211 138 210 3.29E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 Gene3D G3DSA:3.30.230.10 123 214 1.6E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 2.3E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 SUPERFAMILY SSF54768 62 125 1.88E-18 T 23-10-2018 A3L14_02580 37f64008c632bb68a2ac25cf744f1197 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A3L14_05750 fd5cae0d363507ae91dc4c09dde477b9 683 Gene3D G3DSA:3.40.50.880 445 679 2.7E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_05750 fd5cae0d363507ae91dc4c09dde477b9 683 Gene3D G3DSA:2.60.40.10 199 294 1.5E-7 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_05750 fd5cae0d363507ae91dc4c09dde477b9 683 SUPERFAMILY SSF52317 434 681 7.14E-23 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_05750 fd5cae0d363507ae91dc4c09dde477b9 683 Pfam PF09822 ABC-type uncharacterized transport system 216 559 7.6E-10 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 A3L14_00380 40c66472fae31b528ce161df4d6151e7 653 Pfam PF04312 Protein of unknown function (DUF460) 201 340 1.2E-48 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 SUPERFAMILY SSF50447 5 87 1.94E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 23.292 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 Gene3D G3DSA:2.40.10.190 3 88 3.6E-23 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 1.0E-31 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 Pfam PF01247 Ribosomal protein L35Ae 5 87 4.5E-14 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05855 c896133b923e3bc4c05f5582b5602185 88 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 56 77 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08300 9b5bce61dd4746c9a2674bb2cae97138 388 Pfam PF04473 Transglutaminase-like domain 104 250 2.4E-39 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 253 5.0E-31 T 23-10-2018 A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 Gene3D G3DSA:3.40.50.720 2 256 1.4E-47 T 23-10-2018 A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.6E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L14_06195 61aee48223296ca1b5d720e1a82480ab 259 SUPERFAMILY SSF51735 3 254 7.47E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_10335 a31a8a39e25556eb821153ed2be45e45 194 Gene3D G3DSA:1.10.1760.20 1 191 1.8E-19 T 23-10-2018 A3L14_06650 79891df812c1f864f230e4348f9e5e44 223 Gene3D G3DSA:3.40.50.150 1 190 3.7E-52 T 23-10-2018 A3L14_06650 79891df812c1f864f230e4348f9e5e44 223 SUPERFAMILY SSF53335 2 195 1.04E-49 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06650 79891df812c1f864f230e4348f9e5e44 223 Pfam PF08241 Methyltransferase domain 44 133 2.5E-26 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L14_09210 ea13b221bdfd9a1b724b8fb147885498 487 Pfam PF09847 Membrane protein of 12 TMs 41 481 3.9E-75 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L14_09210 ea13b221bdfd9a1b724b8fb147885498 487 PIRSF PIRSF018875 1 486 4.7E-79 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L14_09630 f161b250e46bee7f02340b7df6eb02ca 213 Pfam PF01914 MarC family integral membrane protein 6 211 3.5E-62 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L14_09630 f161b250e46bee7f02340b7df6eb02ca 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 207 9.0E-65 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L14_11080 9df963fb3a5a1469815de783d0cd5def 260 Gene3D G3DSA:3.20.20.105 33 196 1.8E-8 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_11080 9df963fb3a5a1469815de783d0cd5def 260 SUPERFAMILY SSF51713 35 193 2.88E-7 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_01290 8206e5f0827c00fba8b8f9f3efc5a1ad 197 SUPERFAMILY SSF111278 7 193 1.57E-62 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_01290 8206e5f0827c00fba8b8f9f3efc5a1ad 197 Gene3D G3DSA:3.30.1960.10 2 197 8.6E-71 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_01290 8206e5f0827c00fba8b8f9f3efc5a1ad 197 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 31.844 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L14_01290 8206e5f0827c00fba8b8f9f3efc5a1ad 197 Pfam PF02676 Methyltransferase TYW3 11 193 6.1E-48 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L14_02320 6dc1db0768d1a0c11bd7a361937127d9 112 Pfam PF11848 Domain of unknown function (DUF3368) 64 108 4.5E-18 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 SUPERFAMILY SSF51713 88 368 5.36E-25 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 SUPERFAMILY SSF52141 446 577 1.44E-16 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 93 367 8.9E-14 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 Gene3D G3DSA:3.20.20.105 80 406 4.6E-34 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 Pfam PF01702 Queuine tRNA-ribosyltransferase 121 367 6.2E-14 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L14_07970 727ea627de9e6238aa20569bf35ba1a6 611 Gene3D G3DSA:3.40.50.10630 428 592 1.1E-24 T 23-10-2018 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 SMART SM00790 4 207 5.8E-132 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 SUPERFAMILY SSF48310 211 604 1.96E-140 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 1.7E-84 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 SUPERFAMILY SSF56228 1 209 1.57E-80 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 602 1.7E-140 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 Gene3D G3DSA:1.10.599.10 240 602 7.9E-152 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 Gene3D G3DSA:1.10.569.10 242 428 7.9E-152 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L14_09875 f4f9de07e18f26ce0184736040c02ab0 605 Gene3D G3DSA:3.60.9.10 1 211 3.4E-96 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 Gene3D G3DSA:3.10.580.10 1 73 4.8E-7 T 23-10-2018 A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 Gene3D G3DSA:3.10.580.10 83 156 3.5E-12 T 23-10-2018 A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 SUPERFAMILY SSF54631 5 152 1.48E-21 T 23-10-2018 A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 SMART SM00116 105 152 2.0E-4 T 23-10-2018 IPR000644 CBS domain A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 SMART SM00116 24 72 1.9 T 23-10-2018 IPR000644 CBS domain A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 Pfam PF00571 CBS domain 99 152 8.2E-9 T 23-10-2018 IPR000644 CBS domain A3L14_04385 6b7d2e114ad49eb424a0c946f068d93f 164 Pfam PF00571 CBS domain 26 72 3.0E-5 T 23-10-2018 IPR000644 CBS domain A3L14_05455 9f3a1877a29dcd92a30482b4e25d9edb 362 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 154 1.1E-16 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L14_05455 9f3a1877a29dcd92a30482b4e25d9edb 362 SUPERFAMILY SSF54534 3 156 4.52E-41 T 23-10-2018 A3L14_05455 9f3a1877a29dcd92a30482b4e25d9edb 362 Gene3D G3DSA:3.10.50.80 3 166 1.5E-50 T 23-10-2018 A3L14_00535 a2457fa530dc82372e5dddce046dde91 305 SUPERFAMILY SSF52402 24 245 1.59E-51 T 23-10-2018 A3L14_00535 a2457fa530dc82372e5dddce046dde91 305 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 291 8.3E-26 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L14_00535 a2457fa530dc82372e5dddce046dde91 305 Gene3D G3DSA:3.40.50.620 1 303 4.9E-91 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_00535 a2457fa530dc82372e5dddce046dde91 305 PIRSF PIRSF004976 1 302 2.0E-96 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L14_00535 a2457fa530dc82372e5dddce046dde91 305 Pfam PF01171 PP-loop family 50 220 2.2E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L14_10515 7f83c810b1201742f14f61349726ac5d 215 Pfam PF01865 Protein of unknown function DUF47 7 211 2.9E-41 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L14_10515 7f83c810b1201742f14f61349726ac5d 215 Gene3D G3DSA:1.20.58.220 3 212 8.3E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_10515 7f83c810b1201742f14f61349726ac5d 215 SUPERFAMILY SSF109755 23 209 6.1E-8 T 23-10-2018 A3L14_10515 7f83c810b1201742f14f61349726ac5d 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 2.5E-36 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L14_09505 19ccb499336b3db72de0d9641a54e804 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 38.801 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A3L14_09505 19ccb499336b3db72de0d9641a54e804 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 2.0E-33 T 23-10-2018 A3L14_09505 19ccb499336b3db72de0d9641a54e804 224 SUPERFAMILY SSF56281 1 223 6.16E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_09505 19ccb499336b3db72de0d9641a54e804 224 Gene3D G3DSA:3.60.15.10 2 224 2.8E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_09505 19ccb499336b3db72de0d9641a54e804 224 SMART SM00849 8 189 4.4E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_01700 2400b1b106b7d72a8b757b52d535631a 195 Gene3D G3DSA:3.90.1720.10 52 180 1.5E-14 T 23-10-2018 A3L14_01700 2400b1b106b7d72a8b757b52d535631a 195 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 41 191 1.6E-25 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family A3L14_01700 2400b1b106b7d72a8b757b52d535631a 195 SUPERFAMILY SSF54001 41 191 1.23E-26 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.782 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 Gene3D G3DSA:3.40.50.10800 8 282 4.3E-125 T 23-10-2018 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 1.7E-113 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 SUPERFAMILY SSF142754 5 301 5.49E-116 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 1 302 2.3E-118 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 Gene3D G3DSA:3.40.50.10800 173 257 4.3E-125 T 23-10-2018 A3L14_01330 dfbeb9c25a310e8d9cd03708d717bb32 302 Gene3D G3DSA:3.40.50.10800 88 300 4.3E-125 T 23-10-2018 A3L14_04980 0087a2a2b36aa6de61049d7a08b17d60 418 Pfam PF02163 Peptidase family M50 304 349 2.0E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 2.8E-23 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 Pfam PF14697 4Fe-4S dicluster domain 64 116 1.9E-9 T 23-10-2018 A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 SUPERFAMILY SSF52540 2 293 2.54E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 SUPERFAMILY SSF54862 64 138 3.89E-16 T 23-10-2018 A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 Gene3D G3DSA:3.30.70.20 69 115 4.6E-10 T 23-10-2018 A3L14_07585 54c318fe79acf4b75a2985255eab003c 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_09345 39d8707407586473fa63a57951083071 137 Pfam PF01877 RNA binding 6 115 4.9E-17 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L14_09345 39d8707407586473fa63a57951083071 137 SUPERFAMILY SSF55282 6 136 1.88E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09345 39d8707407586473fa63a57951083071 137 Gene3D G3DSA:3.30.1440.10 1 136 3.4E-44 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09345 39d8707407586473fa63a57951083071 137 Hamap MF_01112 UPF0201 protein . 5 134 25.494 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L14_05695 48f33cbb082c60583d3b2ca0e2307e0c 789 Gene3D G3DSA:3.10.105.10 81 287 2.6E-16 T 23-10-2018 A3L14_05695 48f33cbb082c60583d3b2ca0e2307e0c 789 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 27 271 9.3E-13 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L14_05695 48f33cbb082c60583d3b2ca0e2307e0c 789 Gene3D G3DSA:3.40.190.10 27 80 2.6E-16 T 23-10-2018 A3L14_05695 48f33cbb082c60583d3b2ca0e2307e0c 789 SUPERFAMILY SSF53850 27 287 1.39E-19 T 23-10-2018 A3L14_04310 3e5352961303db310f16a8e9bfcefbb8 581 SUPERFAMILY SSF81585 511 579 3.73E-6 T 23-10-2018 A3L14_04310 3e5352961303db310f16a8e9bfcefbb8 581 Gene3D G3DSA:3.80.30.20 200 457 1.6E-23 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L14_04310 3e5352961303db310f16a8e9bfcefbb8 581 Pfam PF04055 Radical SAM superfamily 204 403 1.6E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_04310 3e5352961303db310f16a8e9bfcefbb8 581 SMART SM00729 200 450 7.8E-30 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_04310 3e5352961303db310f16a8e9bfcefbb8 581 SUPERFAMILY SSF102114 194 443 1.7E-23 T 23-10-2018 A3L14_10765 38a9c054b1bf0b452768bb58bf615663 220 Gene3D G3DSA:3.40.50.300 1 219 6.9E-51 T 23-10-2018 A3L14_10765 38a9c054b1bf0b452768bb58bf615663 220 Pfam PF00005 ABC transporter 17 155 3.4E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_10765 38a9c054b1bf0b452768bb58bf615663 220 SUPERFAMILY SSF52540 2 216 1.13E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10765 38a9c054b1bf0b452768bb58bf615663 220 SMART SM00382 25 211 7.6E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_09125 bf8609bcf1ee70e268c1102dd74dbcf6 492 SUPERFAMILY SSF53743 50 330 3.01E-47 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L14_09125 bf8609bcf1ee70e268c1102dd74dbcf6 492 Pfam PF02952 L-fucose isomerase, C-terminal domain 348 478 6.0E-25 T 23-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 A3L14_01355 35f8568e7681afd4ee464fa59a034e46 62 Pfam PF01954 Protein of unknown function DUF104 1 59 3.6E-10 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_01355 35f8568e7681afd4ee464fa59a034e46 62 Gene3D G3DSA:4.10.1150.10 1 60 2.0E-7 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L14_01355 35f8568e7681afd4ee464fa59a034e46 62 SUPERFAMILY SSF141694 1 55 2.51E-10 T 23-10-2018 A3L14_09420 2ed519e69504d535eac735132bd9611a 90 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 84 1.7E-15 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L14_09420 2ed519e69504d535eac735132bd9611a 90 Pfam PF06271 RDD family 6 90 8.5E-5 T 23-10-2018 IPR010432 RDD A3L14_04840 3aa2e91a8e7dddba2c76df2be3228a6e 197 Gene3D G3DSA:3.40.50.12280 3 162 1.3E-49 T 23-10-2018 A3L14_04840 3aa2e91a8e7dddba2c76df2be3228a6e 197 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 24 135 1.8E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04840 3aa2e91a8e7dddba2c76df2be3228a6e 197 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 7 141 8.5E-43 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04840 3aa2e91a8e7dddba2c76df2be3228a6e 197 SUPERFAMILY SSF56770 5 154 2.22E-50 T 23-10-2018 A3L14_05565 b528519190d4e1815f15b4a13eca2d00 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 138 9.914 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_05565 b528519190d4e1815f15b4a13eca2d00 138 Gene3D G3DSA:3.40.50.1010 2 138 3.0E-21 T 23-10-2018 A3L14_05565 b528519190d4e1815f15b4a13eca2d00 138 Pfam PF01850 PIN domain 3 132 8.6E-25 T 23-10-2018 IPR002716 PIN domain A3L14_05565 b528519190d4e1815f15b4a13eca2d00 138 SUPERFAMILY SSF88723 1 136 2.05E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05565 b528519190d4e1815f15b4a13eca2d00 138 SMART SM00670 1 130 5.7E-4 T 23-10-2018 IPR002716 PIN domain A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 155 2.2E-14 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 451 34.121 T 23-10-2018 IPR023935 Replication factor C, large subunit A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 SUPERFAMILY SSF52540 4 212 3.91E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 Gene3D G3DSA:1.10.8.60 160 217 3.5E-11 T 23-10-2018 A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 SMART SM00382 42 159 7.2E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_10165 846482ca07d6b504ceddd27b32af5aea 492 Gene3D G3DSA:3.40.50.300 4 157 2.2E-35 T 23-10-2018 A3L14_02745 dc3e261842dbb835ae55b827578d5a86 251 SUPERFAMILY SSF56300 1 250 1.49E-57 T 23-10-2018 A3L14_02745 dc3e261842dbb835ae55b827578d5a86 251 Gene3D G3DSA:3.60.21.10 1 251 4.1E-49 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_02745 dc3e261842dbb835ae55b827578d5a86 251 PIRSF PIRSF000883 2 251 8.4E-27 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L14_04610 610aa06f27b7095268b90267cb42d232 391 Gene3D G3DSA:3.40.190.10 63 376 1.6E-103 T 23-10-2018 A3L14_04610 610aa06f27b7095268b90267cb42d232 391 SUPERFAMILY SSF53850 58 388 2.69E-87 T 23-10-2018 A3L14_04610 610aa06f27b7095268b90267cb42d232 391 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 59 389 1.7E-124 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A3L14_04610 610aa06f27b7095268b90267cb42d232 391 Pfam PF12849 PBP superfamily domain 50 359 1.1E-57 T 23-10-2018 IPR024370 PBP domain A3L14_04610 610aa06f27b7095268b90267cb42d232 391 Gene3D G3DSA:3.40.190.10 139 325 1.6E-103 T 23-10-2018 A3L14_04610 610aa06f27b7095268b90267cb42d232 391 PIRSF PIRSF002756 1 391 1.4E-112 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A3L14_05280 c3af794532ffe379a972145f124cec8f 311 SUPERFAMILY SSF46785 240 303 4.21E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05280 c3af794532ffe379a972145f124cec8f 311 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 244 302 3.7E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_05280 c3af794532ffe379a972145f124cec8f 311 Gene3D G3DSA:1.10.10.10 234 309 2.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04625 3b0065de983af74f6fcd3e9c46d1d6e9 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 267 8.6E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_04625 3b0065de983af74f6fcd3e9c46d1d6e9 276 SUPERFAMILY SSF161098 19 265 3.46E-32 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04625 3b0065de983af74f6fcd3e9c46d1d6e9 276 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 11 270 9.8E-64 T 23-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A3L14_04625 3b0065de983af74f6fcd3e9c46d1d6e9 276 Gene3D G3DSA:1.10.3720.10 5 267 3.6E-25 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_11410 7ce4aa18e2accc8924c493a1d5927522 176 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 4 170 2.7E-14 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L14_10830 beed6de2e5b672a97b15ca312ead3860 183 Pfam PF00156 Phosphoribosyl transferase domain 35 167 2.0E-24 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L14_10830 beed6de2e5b672a97b15ca312ead3860 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 28.662 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10830 beed6de2e5b672a97b15ca312ead3860 183 SUPERFAMILY SSF53271 4 166 2.75E-49 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L14_10830 beed6de2e5b672a97b15ca312ead3860 183 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 171 4.2E-54 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L14_10830 beed6de2e5b672a97b15ca312ead3860 183 Gene3D G3DSA:3.40.50.2020 1 177 1.2E-61 T 23-10-2018 A3L14_04875 df0975199e793444fd11d027595e8228 138 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 9.5E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_04875 df0975199e793444fd11d027595e8228 138 Pfam PF03334 Na+/H+ antiporter subunit 11 95 1.1E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 SUPERFAMILY SSF54373 223 321 1.29E-9 T 23-10-2018 A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 Pfam PF04324 BFD-like [2Fe-2S] binding domain 407 465 9.3E-11 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 Gene3D G3DSA:3.50.50.60 5 356 1.3E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 Gene3D G3DSA:1.10.10.1100 393 474 3.2E-16 T 23-10-2018 A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 Pfam PF01266 FAD dependent oxidoreductase 5 360 3.2E-69 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 SUPERFAMILY SSF51905 3 271 1.73E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10710 5b9d0756e21a2d773847a0cb9b2002d8 499 Gene3D G3DSA:3.30.9.10 90 322 1.3E-111 T 23-10-2018 A3L14_04450 13e41d2fef730237da384d39d71af816 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 1.7E-51 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L14_04450 13e41d2fef730237da384d39d71af816 219 Gene3D G3DSA:3.40.1280.10 1 218 2.8E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L14_04450 13e41d2fef730237da384d39d71af816 219 SUPERFAMILY SSF75217 1 215 1.18E-62 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L14_04450 13e41d2fef730237da384d39d71af816 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.482 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 2.6E-77 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 605 2.3E-111 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 Gene3D G3DSA:1.10.569.10 239 417 4.9E-134 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 SUPERFAMILY SSF48310 211 617 7.19E-127 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 SMART SM00790 4 205 2.0E-117 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 Gene3D G3DSA:1.10.599.10 237 605 4.9E-134 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 SUPERFAMILY SSF56228 1 209 5.89E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_06460 5342a346f2591b2460b352caa8ccdbb4 619 Gene3D G3DSA:3.60.9.10 1 209 1.1E-89 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_10835 5b74fa92110395a04c2f7edfe86039f4 245 Pfam PF13367 Protease prsW family 45 200 5.1E-5 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 Gene3D G3DSA:1.10.150.240 15 100 2.6E-58 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 SUPERFAMILY SSF56784 1 230 7.43E-47 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 4.8E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 4.8E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 4.8E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 4.8E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 2.7E-54 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 Gene3D G3DSA:3.40.50.1000 3 222 2.6E-58 T 23-10-2018 IPR023214 HAD superfamily A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 200 6.9E-26 T 23-10-2018 A3L14_08935 7cce7e295d9b64065443c967a29ee13a 240 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 196 6.8E-10 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 Pfam PF00149 Calcineurin-like phosphoesterase 1 184 1.3E-19 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 SUPERFAMILY SSF56300 269 481 1.58E-27 T 23-10-2018 A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 SUPERFAMILY SSF56300 1 237 7.18E-50 T 23-10-2018 A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 Gene3D G3DSA:3.60.21.10 1 251 9.5E-40 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 Gene3D G3DSA:3.60.21.10 255 491 2.7E-18 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_06420 2e02d4b94c48a47145359eeeebe95108 510 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 280 471 5.5E-7 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L14_07300 84b3885f70e5379224486fbd31b05c1f 171 SUPERFAMILY SSF57802 137 170 1.34E-10 T 23-10-2018 A3L14_07300 84b3885f70e5379224486fbd31b05c1f 171 Gene3D G3DSA:1.20.1260.10 2 132 3.8E-48 T 23-10-2018 IPR012347 Ferritin-like A3L14_07300 84b3885f70e5379224486fbd31b05c1f 171 Gene3D G3DSA:2.20.28.10 133 171 2.2E-19 T 23-10-2018 A3L14_07300 84b3885f70e5379224486fbd31b05c1f 171 SUPERFAMILY SSF47240 4 133 4.61E-39 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07300 84b3885f70e5379224486fbd31b05c1f 171 Pfam PF02915 Rubrerythrin 10 124 7.3E-26 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 8.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 8.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 8.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 8.4E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 Pfam PF00535 Glycosyl transferase family 2 221 343 1.9E-23 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 Gene3D G3DSA:3.90.550.10 214 437 1.2E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 Gene3D G3DSA:1.10.150.240 18 80 3.3E-29 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 1.0E-21 T 23-10-2018 A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 Gene3D G3DSA:3.40.50.1000 6 184 3.3E-29 T 23-10-2018 IPR023214 HAD superfamily A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 SUPERFAMILY SSF53448 219 429 4.15E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_09985 d5c6b649946c4d84a3fee134e1f7050d 440 SUPERFAMILY SSF56784 1 217 2.2E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_09040 f7909edc693d60a9071d545ff7a6e7b2 141 SMART SM00881 18 111 1.3E-28 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_09040 f7909edc693d60a9071d545ff7a6e7b2 141 Gene3D G3DSA:3.40.50.720 4 141 2.0E-49 T 23-10-2018 A3L14_09040 f7909edc693d60a9071d545ff7a6e7b2 141 SUPERFAMILY SSF51735 7 140 2.49E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_09040 f7909edc693d60a9071d545ff7a6e7b2 141 Pfam PF13380 CoA binding domain 23 137 8.9E-40 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_11150 bcb27f219b6cfb7ef0465f2e1b4d52e8 158 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 150 3.3E-35 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_11150 bcb27f219b6cfb7ef0465f2e1b4d52e8 158 Pfam PF00717 Peptidase S24-like 39 90 1.2E-7 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L14_11150 bcb27f219b6cfb7ef0465f2e1b4d52e8 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 7.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_11150 bcb27f219b6cfb7ef0465f2e1b4d52e8 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 7.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_11150 bcb27f219b6cfb7ef0465f2e1b4d52e8 158 SUPERFAMILY SSF51306 36 124 1.92E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 9.5E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 Gene3D G3DSA:1.10.1220.10 10 50 1.7E-21 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 4.0E-34 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 SUPERFAMILY SSF55021 53 133 6.87E-29 T 23-10-2018 A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.61 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 SUPERFAMILY SSF47598 2 49 4.67E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_02985 1b433979c1c573d8db0b3458e70e56cf 138 Gene3D G3DSA:3.30.70.1150 51 138 1.1E-37 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L14_02465 f939d416a2631e49ce0861ec50abc06f 192 SUPERFAMILY SSF81301 30 167 7.85E-7 T 23-10-2018 A3L14_02465 f939d416a2631e49ce0861ec50abc06f 192 Gene3D G3DSA:3.30.460.40 10 165 3.3E-6 T 23-10-2018 A3L14_07890 35275527c91baaa4232675d8d2df0faa 542 Gene3D G3DSA:1.10.390.40 83 160 3.9E-59 T 23-10-2018 A3L14_07890 35275527c91baaa4232675d8d2df0faa 542 Pfam PF00437 Type II/IV secretion system protein 163 408 6.3E-49 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L14_07890 35275527c91baaa4232675d8d2df0faa 542 SUPERFAMILY SSF52540 143 520 1.02E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_07890 35275527c91baaa4232675d8d2df0faa 542 Gene3D G3DSA:3.40.50.300 261 538 1.5E-89 T 23-10-2018 A3L14_07890 35275527c91baaa4232675d8d2df0faa 542 Gene3D G3DSA:3.30.450.370 48 258 3.9E-59 T 23-10-2018 A3L14_09410 c654197ab98378fc9228e8925814b797 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.625 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L14_09410 c654197ab98378fc9228e8925814b797 134 Gene3D G3DSA:2.40.50.100 2 132 2.3E-52 T 23-10-2018 A3L14_09410 c654197ab98378fc9228e8925814b797 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A3L14_09410 c654197ab98378fc9228e8925814b797 134 SUPERFAMILY SSF51230 10 133 9.42E-43 T 23-10-2018 IPR011053 Single hybrid motif A3L14_09410 c654197ab98378fc9228e8925814b797 134 Pfam PF01597 Glycine cleavage H-protein 13 133 3.2E-50 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A3L14_09410 c654197ab98378fc9228e8925814b797 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 1.4E-46 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 257 8.4E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 SUPERFAMILY SSF52343 89 256 1.58E-16 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 PIRSF PIRSF006816 1 263 5.5E-66 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 Gene3D G3DSA:3.40.50.80 100 211 7.8E-26 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 SUPERFAMILY SSF63380 2 93 3.69E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L14_09395 1dea171d454d474b0fa292ce80f8f9e6 288 Gene3D G3DSA:2.40.30.10 1 92 3.1E-15 T 23-10-2018 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 SMART SM00344 5 111 2.4E-18 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 Gene3D G3DSA:1.10.10.10 1 56 7.4E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 Gene3D G3DSA:3.30.70.920 57 149 1.1E-27 T 23-10-2018 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 6.6E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 6.6E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 6.6E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 SUPERFAMILY SSF46785 5 65 1.69E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 SUPERFAMILY SSF54909 66 146 7.51E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.0E-15 T 23-10-2018 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 8.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L14_05045 d6dfc4c051c45aa45958a2c17fb2fd00 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 8.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L14_02245 8de648e66b33aa8f42c4e4fea3992b6d 401 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 399 4.5E-159 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L14_02245 8de648e66b33aa8f42c4e4fea3992b6d 401 PIRSF PIRSF015658 1 401 1.1E-168 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L14_02245 8de648e66b33aa8f42c4e4fea3992b6d 401 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 395 6.9E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L14_06805 5197da98a441d675823a04bfabfd2ffd 223 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_06805 5197da98a441d675823a04bfabfd2ffd 223 SUPERFAMILY SSF52540 2 214 7.58E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06805 5197da98a441d675823a04bfabfd2ffd 223 Pfam PF00005 ABC transporter 17 155 6.9E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06805 5197da98a441d675823a04bfabfd2ffd 223 SMART SM00382 25 203 3.7E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_06805 5197da98a441d675823a04bfabfd2ffd 223 Gene3D G3DSA:3.40.50.300 1 220 1.6E-46 T 23-10-2018 A3L14_03815 7e4938b295e78247be7e7654af04a870 264 Gene3D G3DSA:3.30.870.10 122 264 3.7E-78 T 23-10-2018 A3L14_03815 7e4938b295e78247be7e7654af04a870 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_03815 7e4938b295e78247be7e7654af04a870 264 SUPERFAMILY SSF46785 10 96 6.96E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03815 7e4938b295e78247be7e7654af04a870 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03815 7e4938b295e78247be7e7654af04a870 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 126 262 1.7E-5 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 SUPERFAMILY SSF54631 5 132 3.03E-31 T 23-10-2018 A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 Gene3D G3DSA:3.10.580.10 3 175 8.1E-42 T 23-10-2018 A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 Pfam PF00571 CBS domain 72 125 6.6E-12 T 23-10-2018 IPR000644 CBS domain A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 Pfam PF00571 CBS domain 7 60 5.7E-11 T 23-10-2018 IPR000644 CBS domain A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 SMART SM00116 14 61 3.8E-9 T 23-10-2018 IPR000644 CBS domain A3L14_07665 b6cdf94ea7a87b4d6a42bb5e29a9694e 177 SMART SM00116 79 126 1.2E-7 T 23-10-2018 IPR000644 CBS domain A3L14_01130 922668825cb5875bde99494c468741ff 380 SUPERFAMILY SSF53649 33 323 2.29E-23 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_01130 922668825cb5875bde99494c468741ff 380 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 10 273 6.9E-20 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L14_01130 922668825cb5875bde99494c468741ff 380 SUPERFAMILY SSF53649 310 350 3.14E-5 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_05905 05d58d4bfbc92addb027c5dba20a1479 120 Pfam PF09685 Domain of unknown function (DUF4870) 24 106 7.0E-10 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 Pfam PF01814 Hemerythrin HHE cation binding domain 94 233 2.5E-19 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 SUPERFAMILY SSF55785 324 422 1.28E-9 T 23-10-2018 IPR035965 PAS domain superfamily A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 Gene3D G3DSA:3.30.450.20 307 442 6.0E-45 T 23-10-2018 A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 Pfam PF13596 PAS domain 326 430 1.0E-22 T 23-10-2018 A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 Gene3D G3DSA:1.20.120.520 87 306 2.1E-59 T 23-10-2018 A3L14_04785 190a08c20c5c5dfb7ae003e951aafa83 446 Pfam PF04282 Family of unknown function (DUF438) 15 79 2.1E-24 T 23-10-2018 IPR007380 Domain of unknown function DUF438 A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 SUPERFAMILY SSF47973 16 215 9.42E-63 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 Gene3D G3DSA:1.10.455.10 15 215 5.9E-79 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 PIRSF PIRSF002122 1 215 4.9E-48 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 Pfam PF00177 Ribosomal protein S7p/S5e 54 215 9.2E-39 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 2.3E-89 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_03390 6beec0e0322c06ff0ecf6c97afd21023 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.185 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A3L14_01415 3cf103a71f05d6d3c540c0379a6a5b2c 280 Pfam PF16286 Domain of unknown function (DUF4932) 10 245 3.6E-46 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A3L14_10235 7f19c7e5d04b9aed7fc42fcf8d61224a 473 PIRSF PIRSF008315 1 469 4.8E-200 T 23-10-2018 IPR016539 Uncharacterised conserved protein UCP008315 A3L14_06110 a51749443f3f3c7c5ab1d5913a6d27f4 197 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 8.5E-46 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 Gene3D G3DSA:3.50.50.60 106 223 2.7E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 Gene3D G3DSA:3.50.50.60 3 277 2.7E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 4.0E-22 T 23-10-2018 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.0E-22 T 23-10-2018 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 4.0E-22 T 23-10-2018 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 4.0E-22 T 23-10-2018 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 Gene3D G3DSA:3.30.390.30 298 355 1.6E-19 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 SUPERFAMILY SSF55424 294 350 6.59E-17 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 SUPERFAMILY SSF51905 2 289 1.78E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 3.2E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 3.2E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 3.2E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.2E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_07295 79a3bc5f4457cbe0be3c4b06aa756eb3 360 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 279 5.1E-55 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 91 5.1E-21 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 PIRSF PIRSF000193 1 258 3.8E-70 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 SUPERFAMILY SSF51735 2 149 1.32E-30 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 253 2.1E-77 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 Gene3D G3DSA:3.40.50.720 1 153 8.0E-43 T 23-10-2018 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 SUPERFAMILY SSF48179 150 257 4.76E-34 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 Gene3D G3DSA:1.10.3730.10 154 256 1.3E-35 T 23-10-2018 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 151 253 4.0E-35 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L14_07465 3b3af79aff3c5541da6191bd571c8ee5 259 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 255 25.266 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A3L14_02795 9f9362b3b22d2a190ffe8dce2fbcc23e 433 Gene3D G3DSA:1.25.40.10 3 175 1.7E-14 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_02795 9f9362b3b22d2a190ffe8dce2fbcc23e 433 Gene3D G3DSA:1.25.40.10 274 407 1.0E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_07005 39b805afe9317e67d50caf50e45b04cf 73 Pfam PF09851 Short C-terminal domain 45 71 9.9E-11 T 23-10-2018 IPR018649 SHOCT domain A3L14_04345 2465df2683f676dbc3f0f028424df7d5 293 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 10 280 3.6E-36 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L14_04345 2465df2683f676dbc3f0f028424df7d5 293 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 274 6.3E-39 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L14_04520 7ac46145304eb646dbb9f5a6490f9bba 249 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 7 198 1.0E-51 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L14_04520 7ac46145304eb646dbb9f5a6490f9bba 249 SUPERFAMILY SSF69796 4 198 1.29E-58 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L14_04520 7ac46145304eb646dbb9f5a6490f9bba 249 Gene3D G3DSA:3.30.1360.170 3 202 2.5E-62 T 23-10-2018 A3L14_04520 7ac46145304eb646dbb9f5a6490f9bba 249 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 29.758 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L14_04520 7ac46145304eb646dbb9f5a6490f9bba 249 Pfam PF02511 Thymidylate synthase complementing protein 8 198 1.3E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L14_07350 12769d4853ceb5d27b324e72987e041c 125 SUPERFAMILY SSF46785 5 113 1.29E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07350 12769d4853ceb5d27b324e72987e041c 125 Gene3D G3DSA:1.10.10.10 2 82 2.2E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_07350 12769d4853ceb5d27b324e72987e041c 125 Pfam PF01475 Ferric uptake regulator family 13 122 1.2E-20 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A3L14_00545 71d7d26125bc1b67c8a80a8796a3e56c 201 Gene3D G3DSA:3.40.50.11570 7 199 5.7E-33 T 23-10-2018 A3L14_00545 71d7d26125bc1b67c8a80a8796a3e56c 201 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 15 175 2.4E-25 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_02690 a11d664672ac69051cde913b928aff15 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 6.3E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02690 a11d664672ac69051cde913b928aff15 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.194 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02690 a11d664672ac69051cde913b928aff15 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A3L14_02690 a11d664672ac69051cde913b928aff15 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.4E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A3L14_02690 a11d664672ac69051cde913b928aff15 135 SUPERFAMILY SSF54211 3 135 5.31E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L14_02690 a11d664672ac69051cde913b928aff15 135 Gene3D G3DSA:3.30.230.10 1 135 5.3E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 8 116 1.8E-19 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 Pfam PF00717 Peptidase S24-like 36 93 9.0E-12 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 9.3E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 9.3E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 SUPERFAMILY SSF51306 34 114 2.49E-12 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L14_01565 2ecf46a5f67385b2b63267d43e1db63f 354 Gene3D G3DSA:2.10.109.10 36 95 1.3E-6 T 23-10-2018 A3L14_06210 765ed6f4380d1f9b262bc828740d9b9d 315 PIRSF PIRSF006004 1 305 7.0E-41 T 23-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A3L14_06210 765ed6f4380d1f9b262bc828740d9b9d 315 Gene3D G3DSA:3.20.20.70 11 274 3.4E-28 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_06210 765ed6f4380d1f9b262bc828740d9b9d 315 SUPERFAMILY SSF102114 42 222 3.27E-12 T 23-10-2018 A3L14_06210 765ed6f4380d1f9b262bc828740d9b9d 315 Pfam PF04055 Radical SAM superfamily 46 210 3.9E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_08795 664dac1e7e154581a3adfe3b42c25a2c 236 SUPERFAMILY SSF56317 1 219 2.49E-39 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L14_08795 664dac1e7e154581a3adfe3b42c25a2c 236 Pfam PF00795 Carbon-nitrogen hydrolase 2 221 6.0E-17 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L14_08795 664dac1e7e154581a3adfe3b42c25a2c 236 Gene3D G3DSA:3.60.110.10 1 232 1.5E-35 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L14_02280 8cf461279c53de4f7cebcfb9e136cc57 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A3L14_02280 8cf461279c53de4f7cebcfb9e136cc57 170 SUPERFAMILY SSF56300 1 160 1.11E-38 T 23-10-2018 A3L14_02280 8cf461279c53de4f7cebcfb9e136cc57 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 3.8E-38 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L14_02280 8cf461279c53de4f7cebcfb9e136cc57 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 3.2E-33 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L14_02280 8cf461279c53de4f7cebcfb9e136cc57 170 Gene3D G3DSA:3.60.21.10 1 159 2.7E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_03005 933b70dacb999e623014a65a82b0feea 105 ProSitePatterns PS00638 P-II protein C-terminal region signature. 75 88 - T 23-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A3L14_03005 933b70dacb999e623014a65a82b0feea 105 SMART SM00938 4 97 4.0E-42 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L14_03005 933b70dacb999e623014a65a82b0feea 105 SUPERFAMILY SSF54913 1 104 2.22E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L14_03005 933b70dacb999e623014a65a82b0feea 105 PRINTS PR00340 P-II protein signature 44 67 4.8E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L14_03005 933b70dacb999e623014a65a82b0feea 105 PRINTS PR00340 P-II protein signature 75 95 4.8E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L14_03005 933b70dacb999e623014a65a82b0feea 105 PRINTS PR00340 P-II protein signature 2 17 4.8E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L14_03005 933b70dacb999e623014a65a82b0feea 105 Gene3D G3DSA:3.30.70.120 1 105 9.4E-39 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L14_03005 933b70dacb999e623014a65a82b0feea 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.1E-29 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L14_01930 4909fec35c169575487b9b663923c67c 334 Gene3D G3DSA:3.40.50.300 4 236 2.5E-76 T 23-10-2018 A3L14_01930 4909fec35c169575487b9b663923c67c 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_01930 4909fec35c169575487b9b663923c67c 334 SUPERFAMILY SSF52540 4 241 1.12E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01930 4909fec35c169575487b9b663923c67c 334 SMART SM00382 27 218 4.0E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01930 4909fec35c169575487b9b663923c67c 334 Pfam PF00005 ABC transporter 22 160 5.1E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_02365 9e468c40929af6149a509217879fa3a6 224 Gene3D G3DSA:3.40.50.11570 6 217 6.8E-51 T 23-10-2018 A3L14_02365 9e468c40929af6149a509217879fa3a6 224 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 214 2.1E-61 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_11310 a9e71f9da207019a872d903054b3816f 97 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 83 3.5E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L14_00905 c4b2a0f44ce341a58400350b0996bb78 111 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 102 5.2E-15 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D A3L14_00905 c4b2a0f44ce341a58400350b0996bb78 111 Gene3D G3DSA:1.10.10.1150 40 104 1.6E-8 T 23-10-2018 A3L14_09945 e7bfab1a498f40c55dba5348944a1b88 243 Gene3D G3DSA:1.10.260.40 24 80 7.9E-11 T 23-10-2018 A3L14_09945 e7bfab1a498f40c55dba5348944a1b88 243 SUPERFAMILY SSF47413 22 75 4.1E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_09945 e7bfab1a498f40c55dba5348944a1b88 243 PIRSF PIRSF037724 1 237 4.0E-105 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A3L14_09945 e7bfab1a498f40c55dba5348944a1b88 243 SMART SM00530 26 81 1.1E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_09945 e7bfab1a498f40c55dba5348944a1b88 243 Pfam PF01381 Helix-turn-helix 28 75 4.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:2.170.16.10 564 632 1.2E-16 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:2.170.16.10 149 289 6.0E-38 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:1.10.150.20 40 103 7.4E-25 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:3.40.50.300 104 148 4.2E-11 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Pfam PF14528 LAGLIDADG-like domain 371 437 6.7E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SMART SM00305 592 637 5.1E-13 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SUPERFAMILY SSF52540 632 835 8.73E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Pfam PF14520 Helix-hairpin-helix domain 40 95 1.1E-11 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:3.40.50.300 633 836 3.5E-63 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 631 836 6.4E-109 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SMART SM00306 148 269 1.6E-19 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SUPERFAMILY SSF55608 354 437 3.13E-19 T 23-10-2018 IPR027434 Homing endonuclease A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 836 70.137 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Gene3D G3DSA:3.10.28.10 355 451 1.9E-17 T 23-10-2018 IPR027434 Homing endonuclease A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SUPERFAMILY SSF47794 38 98 6.59E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Pfam PF08423 Rad51 102 150 8.4E-13 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Pfam PF08423 Rad51 632 836 2.8E-71 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SUPERFAMILY SSF51294 150 632 4.51E-40 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 609 632 7.9E-7 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 150 246 5.6E-11 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 PRINTS PR00379 Intein signature 282 294 1.3E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 PRINTS PR00379 Intein signature 233 246 1.3E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 PRINTS PR00379 Intein signature 626 635 1.3E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 PRINTS PR00379 Intein signature 607 624 1.3E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 PRINTS PR00379 Intein signature 371 383 1.3E-14 T 23-10-2018 IPR006142 Intein GO:0016539 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SUPERFAMILY SSF52540 80 149 4.56E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 Pfam PF14890 Intein splicing domain 168 631 2.4E-27 T 23-10-2018 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SMART SM00278 73 92 360.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L14_00130 bedb6d8b5877017e2069ed397d30fef1 836 SMART SM00278 40 59 0.011 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L14_02380 8f6e9b5c67cd2bbff87544fc4c335876 246 Gene3D G3DSA:3.40.50.700 3 165 3.3E-36 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L14_02380 8f6e9b5c67cd2bbff87544fc4c335876 246 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 150 2.5E-24 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02380 8f6e9b5c67cd2bbff87544fc4c335876 246 SUPERFAMILY SSF56770 3 212 9.42E-43 T 23-10-2018 A3L14_02975 0ec66cb4456b996d24b892156815d27b 333 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 98 330 9.2E-43 T 23-10-2018 A3L14_02975 0ec66cb4456b996d24b892156815d27b 333 Pfam PF04087 Domain of unknown function (DUF389) 146 284 4.1E-27 T 23-10-2018 IPR005240 Protein of unknown function DUF389 A3L14_04425 4edc31eae4103adb9b34fe89c8cf4988 282 SUPERFAMILY SSF161098 11 282 1.12E-63 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04425 4edc31eae4103adb9b34fe89c8cf4988 282 Gene3D G3DSA:1.10.3720.10 6 273 2.0E-63 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04425 4edc31eae4103adb9b34fe89c8cf4988 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 271 1.6E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_03110 da387e5e9efb0fbadb30ca58e6c11982 388 SUPERFAMILY SSF50249 332 382 5.57E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_03110 da387e5e9efb0fbadb30ca58e6c11982 388 Gene3D G3DSA:2.40.50.140 332 385 9.3E-9 T 23-10-2018 A3L14_03110 da387e5e9efb0fbadb30ca58e6c11982 388 Pfam PF04981 NMD3 family 6 276 9.9E-61 T 23-10-2018 IPR007064 Nmd3, N-terminal A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 Gene3D G3DSA:3.60.9.10 2 228 6.1E-25 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 SMART SM00790 1 226 3.0E-71 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 576 4.2E-18 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 Gene3D G3DSA:1.10.569.10 280 473 4.1E-13 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 SUPERFAMILY SSF48310 254 651 7.32E-67 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 3.9E-41 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L14_10725 6d6b81072ca61430f41104a9f43546bb 652 SUPERFAMILY SSF56228 3 228 5.75E-46 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L14_01280 4b4be062b2581efa6bda029bfdf6cd1c 90 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 2 88 2.0E-18 T 23-10-2018 A3L14_07595 d9a6d56fbffe9ca5d1cf487d2344dd08 128 Gene3D G3DSA:3.30.420.130 2 124 3.0E-16 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_07595 d9a6d56fbffe9ca5d1cf487d2344dd08 128 SUPERFAMILY SSF53146 3 114 1.57E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_07595 d9a6d56fbffe9ca5d1cf487d2344dd08 128 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 112 2.6E-15 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L14_10260 dc1bb16af400a4f31a9f8e2eef3413bd 263 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 253 1.9E-14 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A3L14_10260 dc1bb16af400a4f31a9f8e2eef3413bd 263 Gene3D G3DSA:3.40.830.10 1 262 1.7E-69 T 23-10-2018 A3L14_10260 dc1bb16af400a4f31a9f8e2eef3413bd 263 SUPERFAMILY SSF53213 5 259 3.79E-24 T 23-10-2018 A3L14_07125 2d1032c12517f27b44e43f73c88461c7 68 Pfam PF00403 Heavy-metal-associated domain 5 64 6.3E-11 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L14_07125 2d1032c12517f27b44e43f73c88461c7 68 Gene3D G3DSA:3.30.70.100 1 66 3.8E-17 T 23-10-2018 A3L14_07125 2d1032c12517f27b44e43f73c88461c7 68 SUPERFAMILY SSF55008 1 67 2.49E-17 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 SUPERFAMILY SSF102522 1 161 7.59E-55 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 SUPERFAMILY SSF101852 163 254 4.18E-25 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 6.4E-77 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 Gene3D G3DSA:3.40.50.10790 1 160 1.4E-59 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 PIRSF PIRSF006779 1 256 4.6E-78 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L14_08915 c016e997e19f313d8d086c79971a13eb 256 Gene3D G3DSA:2.40.30.90 161 256 2.7E-34 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L14_08950 e5a40842aa95f5cb99d214b19dc116d0 112 SMART SM01022 6 109 1.1E-11 T 23-10-2018 IPR007374 ASCH domain A3L14_08950 e5a40842aa95f5cb99d214b19dc116d0 112 Gene3D G3DSA:2.30.130.30 1 112 3.5E-40 T 23-10-2018 A3L14_08950 e5a40842aa95f5cb99d214b19dc116d0 112 PIRSF PIRSF016134 2 111 8.6E-45 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L14_08950 e5a40842aa95f5cb99d214b19dc116d0 112 SUPERFAMILY SSF88697 1 108 9.2E-32 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_08950 e5a40842aa95f5cb99d214b19dc116d0 112 Pfam PF04266 ASCH domain 7 107 2.1E-12 T 23-10-2018 IPR007374 ASCH domain A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 1.1E-19 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 Gene3D G3DSA:3.30.70.3130 1 101 1.8E-35 T 23-10-2018 A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 SUPERFAMILY SSF53335 8 308 1.21E-75 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 Gene3D G3DSA:3.40.50.150 103 309 7.3E-69 T 23-10-2018 A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 3.7E-90 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 2.3E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 2.3E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 2.3E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 2.3E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 2.3E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L14_04470 b27fd85fb9d38371846ffeae6d1d4eb9 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 5.8E-59 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L14_07750 6d05c967ade90212f9299dabe653c74e 314 Pfam PF05763 Protein of unknown function (DUF835) 172 310 3.8E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_07750 6d05c967ade90212f9299dabe653c74e 314 SUPERFAMILY SSF47240 12 153 8.33E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07750 6d05c967ade90212f9299dabe653c74e 314 Gene3D G3DSA:1.20.1260.10 5 153 3.4E-33 T 23-10-2018 IPR012347 Ferritin-like A3L14_07750 6d05c967ade90212f9299dabe653c74e 314 Pfam PF02915 Rubrerythrin 15 149 7.9E-23 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_10350 60c9e217d534323466580bc72454e97d 65 SUPERFAMILY SSF141694 1 64 2.46E-15 T 23-10-2018 A3L14_10350 60c9e217d534323466580bc72454e97d 65 Gene3D G3DSA:4.10.1150.10 1 65 4.9E-15 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L14_10350 60c9e217d534323466580bc72454e97d 65 Pfam PF01954 Protein of unknown function DUF104 1 59 1.6E-17 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 Pfam PF00005 ABC transporter 20 162 3.1E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 Gene3D G3DSA:3.40.50.300 1 233 5.0E-75 T 23-10-2018 A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 SMART SM00382 28 212 2.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 SUPERFAMILY SSF52540 3 224 2.09E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 304 4.7E-123 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L14_08115 1b220bdb38da7ac19ad8db38b3bdcbca 326 Pfam PF13732 Domain of unknown function (DUF4162) 217 302 1.2E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L14_01940 3fcdafeb82d46378503376486051ddd8 348 SUPERFAMILY SSF56266 2 345 2.22E-95 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L14_01940 3fcdafeb82d46378503376486051ddd8 348 Pfam PF03576 Peptidase family S58 19 325 1.4E-101 T 23-10-2018 IPR005321 Peptidase S58, DmpA A3L14_01940 3fcdafeb82d46378503376486051ddd8 348 Gene3D G3DSA:3.60.70.12 1 347 7.1E-132 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L14_03925 78ba05c22e6731b556819d16ebb75946 125 Pfam PF04475 Protein of unknown function (DUF555) 3 104 2.8E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L14_03925 78ba05c22e6731b556819d16ebb75946 125 Hamap MF_01223 UPF0212 protein . 1 112 32.377 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L14_03925 78ba05c22e6731b556819d16ebb75946 125 PIRSF PIRSF016934 1 122 7.4E-53 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L14_03925 78ba05c22e6731b556819d16ebb75946 125 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 2.0E-51 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L14_04680 3a7e62d1695b57989616c58a9318a5df 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 37.931 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L14_04680 3a7e62d1695b57989616c58a9318a5df 253 Gene3D G3DSA:3.20.20.70 3 253 3.4E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_04680 3a7e62d1695b57989616c58a9318a5df 253 SUPERFAMILY SSF102114 32 210 1.96E-14 T 23-10-2018 A3L14_04680 3a7e62d1695b57989616c58a9318a5df 253 Pfam PF04055 Radical SAM superfamily 31 188 4.6E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_04680 3a7e62d1695b57989616c58a9318a5df 253 Pfam PF13353 4Fe-4S single cluster domain 29 133 1.1E-6 T 23-10-2018 A3L14_06335 7a8d472d953ceb47151d0997d4458f0c 271 Pfam PF14378 PAP2 superfamily 69 213 5.2E-8 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 A3L14_06335 7a8d472d953ceb47151d0997d4458f0c 271 SUPERFAMILY SSF48317 68 216 1.01E-6 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L14_06335 7a8d472d953ceb47151d0997d4458f0c 271 Gene3D G3DSA:1.20.144.10 144 230 9.0E-6 T 23-10-2018 A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 Gene3D G3DSA:2.160.20.80 78 271 5.3E-6 T 23-10-2018 A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 Gene3D G3DSA:1.10.287.70 431 541 7.7E-13 T 23-10-2018 A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 Pfam PF07885 Ion channel 486 538 2.8E-13 T 23-10-2018 IPR013099 Potassium channel domain A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 Pfam PF13576 Pentapeptide repeats (9 copies) 158 197 2.9E-6 T 23-10-2018 IPR001646 Pentapeptide repeat A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 Pfam PF13576 Pentapeptide repeats (9 copies) 79 119 1.0E-8 T 23-10-2018 IPR001646 Pentapeptide repeat A3L14_09795 579011929ea9c148f2e2c3f54b48a39d 541 SUPERFAMILY SSF81324 433 540 1.7E-14 T 23-10-2018 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 Gene3D G3DSA:3.20.20.70 120 263 5.8E-90 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 4.5E-31 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 1.1E-49 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 SUPERFAMILY SSF51690 104 273 3.26E-48 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 Gene3D G3DSA:3.90.1170.20 10 271 5.8E-90 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 PIRSF PIRSF006250 4 276 1.7E-90 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 SUPERFAMILY SSF54675 5 103 9.89E-31 T 23-10-2018 A3L14_01335 63c46f7d416b5e526cc90b342df0c551 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 2.6E-97 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A3L14_05205 6095afeab8a7dfe521b13f76ece6c339 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 205 4.0E-20 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L14_05205 6095afeab8a7dfe521b13f76ece6c339 218 Gene3D G3DSA:3.60.21.10 1 214 3.5E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L14_05205 6095afeab8a7dfe521b13f76ece6c339 218 SUPERFAMILY SSF56300 1 211 1.9E-66 T 23-10-2018 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 SUPERFAMILY SSF56821 9 439 2.09E-146 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Pfam PF03063 Prismane/CO dehydrogenase family 11 93 7.4E-17 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Pfam PF03063 Prismane/CO dehydrogenase family 90 435 1.1E-95 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Gene3D G3DSA:3.40.50.2030 271 439 9.4E-60 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Gene3D G3DSA:1.20.1270.20 32 117 7.0E-28 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 34 439 5.0E-188 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Gene3D G3DSA:3.40.50.2030 123 270 3.5E-53 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_04765 c312bd631a0e1735bbc7741b9deed7f5 456 Hamap MF_00069 Hydroxylamine reductase [hcp]. 11 440 16.217 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A3L14_06185 97b5c2abb99d87762f131f325c748db5 336 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.326 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A3L14_06185 97b5c2abb99d87762f131f325c748db5 336 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 335 5.9E-122 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L14_06185 97b5c2abb99d87762f131f325c748db5 336 Gene3D G3DSA:3.40.910.10 2 336 1.2E-145 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A3L14_06185 97b5c2abb99d87762f131f325c748db5 336 Pfam PF01916 Deoxyhypusine synthase 34 331 9.8E-112 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L14_06185 97b5c2abb99d87762f131f325c748db5 336 SUPERFAMILY SSF52467 5 334 8.17E-116 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 Gene3D G3DSA:3.60.15.10 3 439 1.1E-137 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 421 1.4E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 SMART SM00849 14 221 2.2E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 440 3.6E-163 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 1.3E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 Gene3D G3DSA:3.40.50.10710 215 374 1.1E-137 T 23-10-2018 A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 50.032 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A3L14_02885 018bbedc5a667048400df5e5b79bd61b 440 SUPERFAMILY SSF56281 2 439 3.69E-68 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_01615 0f09d86595edb4463fde2c4fb75e6caf 237 SUPERFAMILY SSF52540 8 233 2.26E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01615 0f09d86595edb4463fde2c4fb75e6caf 237 Gene3D G3DSA:3.40.50.300 7 235 2.1E-55 T 23-10-2018 A3L14_01615 0f09d86595edb4463fde2c4fb75e6caf 237 Pfam PF06745 KaiC 13 234 4.8E-45 T 23-10-2018 IPR014774 KaiC-like domain A3L14_04805 7859d71debef6134c2402fe460074d20 447 SUPERFAMILY SSF53383 24 430 4.26E-128 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_04805 7859d71debef6134c2402fe460074d20 447 Gene3D G3DSA:3.40.640.10 63 328 8.3E-147 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_04805 7859d71debef6134c2402fe460074d20 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_04805 7859d71debef6134c2402fe460074d20 447 Pfam PF00202 Aminotransferase class-III 26 428 7.8E-112 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_04805 7859d71debef6134c2402fe460074d20 447 PIRSF PIRSF000521 25 431 2.2E-36 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L14_04805 7859d71debef6134c2402fe460074d20 447 Gene3D G3DSA:3.90.1150.10 10 424 8.3E-147 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_04590 95766db22025bc3a0b620d0646fb9b0f 108 Gene3D G3DSA:1.10.10.1220 1 88 1.4E-46 T 23-10-2018 A3L14_03180 b5ec45d6601d4fb2b8db8f23b5cc60ae 193 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 19.288 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A3L14_03180 b5ec45d6601d4fb2b8db8f23b5cc60ae 193 Gene3D G3DSA:3.90.550.10 4 192 1.4E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03180 b5ec45d6601d4fb2b8db8f23b5cc60ae 193 SUPERFAMILY SSF53448 1 185 2.03E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03180 b5ec45d6601d4fb2b8db8f23b5cc60ae 193 Pfam PF12804 MobA-like NTP transferase domain 3 158 8.4E-34 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 31 53 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 133 156 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 176 197 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 157 175 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 201 224 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 78 99 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 PRINTS PR00721 Stomatin signature 113 130 1.4E-72 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 SUPERFAMILY SSF117892 55 188 7.45E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 Gene3D G3DSA:3.30.479.30 52 183 2.1E-51 T 23-10-2018 A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 Pfam PF01145 SPFH domain / Band 7 family 28 198 2.9E-38 T 23-10-2018 IPR001107 Band 7 domain A3L14_08420 103a7eae5c431d3a6d66c8b4d1dcc182 280 SMART SM00244 24 181 5.2E-70 T 23-10-2018 IPR001107 Band 7 domain A3L14_08465 8f55aed55161456c4bfb688da1eb359d 281 SUPERFAMILY SSF63992 1 276 3.53E-79 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A3L14_08465 8f55aed55161456c4bfb688da1eb359d 281 Pfam PF04951 D-aminopeptidase 1 266 4.2E-79 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L14_08465 8f55aed55161456c4bfb688da1eb359d 281 Gene3D G3DSA:3.30.1360.130 119 265 4.3E-75 T 23-10-2018 A3L14_08465 8f55aed55161456c4bfb688da1eb359d 281 Gene3D G3DSA:3.40.50.10780 1 218 4.3E-75 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal A3L14_08465 8f55aed55161456c4bfb688da1eb359d 281 PIRSF PIRSF015853 1 278 3.8E-92 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L14_05160 78f940627081157efd6dabe6ccefb29c 69 SUPERFAMILY SSF50346 1 66 2.67E-15 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L14_05160 78f940627081157efd6dabe6ccefb29c 69 Pfam PF05239 PRC-barrel domain 2 68 4.3E-14 T 23-10-2018 IPR027275 PRC-barrel domain A3L14_05160 78f940627081157efd6dabe6ccefb29c 69 Gene3D G3DSA:2.30.30.240 3 69 4.3E-7 T 23-10-2018 A3L14_06760 46eea7e3f2439fe771671311a3c31edc 473 Gene3D G3DSA:3.30.2290.10 1 195 8.0E-27 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_06760 46eea7e3f2439fe771671311a3c31edc 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 2.7E-57 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_06760 46eea7e3f2439fe771671311a3c31edc 473 PIRSF PIRSF004919 1 472 3.6E-151 T 23-10-2018 IPR025502 TldD A3L14_06760 46eea7e3f2439fe771671311a3c31edc 473 SUPERFAMILY SSF111283 1 468 1.83E-104 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_01960 cfc4e54d6e48bdfcc13395ab62e772db 100 SUPERFAMILY SSF89957 1 96 1.96E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L14_01960 cfc4e54d6e48bdfcc13395ab62e772db 100 Gene3D G3DSA:3.30.70.930 1 97 6.6E-35 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L14_01960 cfc4e54d6e48bdfcc13395ab62e772db 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 2.5E-29 T 23-10-2018 IPR002767 Thiamine-binding protein A3L14_01960 cfc4e54d6e48bdfcc13395ab62e772db 100 Pfam PF01910 Thiamine-binding protein 4 93 5.4E-32 T 23-10-2018 IPR002767 Thiamine-binding protein A3L14_05490 922182d084ce6f4c055e965a5f04028d 205 Pfam PF02581 Thiamine monophosphate synthase 9 184 4.7E-60 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05490 922182d084ce6f4c055e965a5f04028d 205 Gene3D G3DSA:3.20.20.70 2 203 8.8E-72 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_05490 922182d084ce6f4c055e965a5f04028d 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 203 26.974 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05490 922182d084ce6f4c055e965a5f04028d 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 198 6.7E-60 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_05490 922182d084ce6f4c055e965a5f04028d 205 SUPERFAMILY SSF51391 6 201 2.88E-63 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L14_06465 271f3f7d1743d30a142674891e3fe100 76 SUPERFAMILY SSF54285 2 76 1.31E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L14_06465 271f3f7d1743d30a142674891e3fe100 76 Gene3D G3DSA:3.10.20.30 1 76 1.2E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L14_06465 271f3f7d1743d30a142674891e3fe100 76 Pfam PF02597 ThiS family 5 76 6.8E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L14_07870 610cf7adacc1c1e4b305fd346a1acf40 139 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 138 4.1E-16 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L14_07870 610cf7adacc1c1e4b305fd346a1acf40 139 SUPERFAMILY SSF141322 71 138 1.44E-16 T 23-10-2018 A3L14_07870 610cf7adacc1c1e4b305fd346a1acf40 139 Gene3D G3DSA:2.40.50.140 69 139 9.0E-19 T 23-10-2018 A3L14_02520 51bec45fbe2c1eff83035f1a3782260e 97 Pfam PF01868 Domain of unknown function UPF0086 14 93 8.0E-19 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L14_02520 51bec45fbe2c1eff83035f1a3782260e 97 SUPERFAMILY SSF101744 10 96 1.12E-23 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A3L14_02520 51bec45fbe2c1eff83035f1a3782260e 97 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 17 92 18.796 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A3L14_02520 51bec45fbe2c1eff83035f1a3782260e 97 Gene3D G3DSA:2.30.30.210 1 97 3.3E-34 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A3L14_02520 51bec45fbe2c1eff83035f1a3782260e 97 SMART SM00538 9 97 2.5E-31 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L14_11360 52548cfcec45d7b885a2e5835c1b53f4 412 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 376 2.2E-61 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11360 52548cfcec45d7b885a2e5835c1b53f4 412 Gene3D G3DSA:1.10.645.20 7 376 6.9E-118 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11360 52548cfcec45d7b885a2e5835c1b53f4 412 Pfam PF00374 Nickel-dependent hydrogenase 44 112 1.1E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_11360 52548cfcec45d7b885a2e5835c1b53f4 412 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 44 69 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L14_11360 52548cfcec45d7b885a2e5835c1b53f4 412 SUPERFAMILY SSF56762 15 376 1.23E-100 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09355 7adcf5e71f58c48388a5512dbda853f5 185 Gene3D G3DSA:3.40.50.300 1 183 2.1E-46 T 23-10-2018 A3L14_09355 7adcf5e71f58c48388a5512dbda853f5 185 Pfam PF13207 AAA domain 6 137 1.5E-20 T 23-10-2018 A3L14_09355 7adcf5e71f58c48388a5512dbda853f5 185 Hamap MF_01111 UPF0200 protein . 2 182 32.257 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A3L14_09355 7adcf5e71f58c48388a5512dbda853f5 185 SUPERFAMILY SSF52540 1 181 1.89E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02415 626334933c1354f64d4a8e72c56d7509 300 Gene3D G3DSA:3.30.930.10 1 299 4.4E-73 T 23-10-2018 A3L14_02415 626334933c1354f64d4a8e72c56d7509 300 SUPERFAMILY SSF55681 6 295 2.49E-54 T 23-10-2018 A3L14_02415 626334933c1354f64d4a8e72c56d7509 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 292 3.9E-42 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L14_07185 abb06f9b87d2891d44c53f0e9f5660aa 200 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 194 7.2E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_07185 abb06f9b87d2891d44c53f0e9f5660aa 200 SUPERFAMILY SSF53323 2 197 1.23E-39 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_07185 abb06f9b87d2891d44c53f0e9f5660aa 200 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 2 193 3.2E-63 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L14_07185 abb06f9b87d2891d44c53f0e9f5660aa 200 Gene3D G3DSA:3.40.920.10 1 200 1.8E-47 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_05935 73e4b4c71e30e6d7ac199886d5001214 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 8.1E-74 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L14_05935 73e4b4c71e30e6d7ac199886d5001214 177 Pfam PF02441 Flavoprotein 1 156 1.6E-29 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L14_05935 73e4b4c71e30e6d7ac199886d5001214 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.886 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L14_05935 73e4b4c71e30e6d7ac199886d5001214 177 Gene3D G3DSA:3.40.50.1950 1 177 2.6E-75 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L14_05935 73e4b4c71e30e6d7ac199886d5001214 177 SUPERFAMILY SSF52507 1 176 4.84E-60 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 Gene3D G3DSA:3.40.50.720 7 298 2.9E-134 T 23-10-2018 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L14_10510 3276a75bcc6315ad389de46012e45036 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 1.4E-72 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 SUPERFAMILY SSF52283 2 133 3.21E-38 T 23-10-2018 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L14_10510 3276a75bcc6315ad389de46012e45036 304 Gene3D G3DSA:3.40.50.720 92 282 2.9E-134 T 23-10-2018 A3L14_10510 3276a75bcc6315ad389de46012e45036 304 SUPERFAMILY SSF51735 99 280 3.13E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_10510 3276a75bcc6315ad389de46012e45036 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 3.7E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L14_06080 2e632ff31e0d90371ee3af6fd076cb87 179 Gene3D G3DSA:3.90.550.10 2 175 1.5E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_06080 2e632ff31e0d90371ee3af6fd076cb87 179 SUPERFAMILY SSF53448 1 173 1.19E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_06080 2e632ff31e0d90371ee3af6fd076cb87 179 Pfam PF12804 MobA-like NTP transferase domain 3 111 1.0E-15 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L14_09465 af082119c2e583ed5463454ef102ba94 157 Gene3D G3DSA:3.50.20.10 44 156 5.2E-34 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 46.682 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 SUPERFAMILY SSF56271 2 155 2.88E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 154 1.1E-38 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 4.5E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 PIRSF PIRSF005216 2 157 9.3E-47 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 Gene3D G3DSA:3.30.60.30 1 43 3.4E-18 T 23-10-2018 A3L14_09465 af082119c2e583ed5463454ef102ba94 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 4.0E-69 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L14_08675 1c3e3906261dbe4d9ed5132c5c8df53a 138 SMART SM01103 5 92 1.9E-26 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L14_08675 1c3e3906261dbe4d9ed5132c5c8df53a 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 1.0E-36 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L14_08675 1c3e3906261dbe4d9ed5132c5c8df53a 138 SUPERFAMILY SSF75471 5 101 3.4E-18 T 23-10-2018 IPR035920 YhbY-like superfamily A3L14_08675 1c3e3906261dbe4d9ed5132c5c8df53a 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 3.5E-13 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L14_08675 1c3e3906261dbe4d9ed5132c5c8df53a 138 Gene3D G3DSA:3.30.110.60 5 112 2.4E-20 T 23-10-2018 IPR035920 YhbY-like superfamily A3L14_00500 7b625f4ca50e05db8835343405b0059e 82 Pfam PF01998 Protein of unknown function DUF131 33 74 2.4E-13 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L14_09090 8a85003ea771f791c306538bf22ee249 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 3.1E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_09090 8a85003ea771f791c306538bf22ee249 277 Gene3D G3DSA:1.10.3720.10 2 266 1.3E-49 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_09090 8a85003ea771f791c306538bf22ee249 277 SUPERFAMILY SSF161098 8 269 5.36E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Gene3D G3DSA:3.50.40.10 81 278 1.8E-73 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 3.6E-13 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 36.166 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Gene3D G3DSA:3.30.56.10 279 348 5.5E-26 T 23-10-2018 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SUPERFAMILY SSF56037 142 258 1.18E-5 T 23-10-2018 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Pfam PF03483 B3/4 domain 119 243 5.6E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SUPERFAMILY SSF55681 345 562 2.4E-45 T 23-10-2018 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 557 1.8E-178 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SUPERFAMILY SSF46955 5 81 6.13E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Gene3D G3DSA:3.30.930.10 367 562 5.2E-50 T 23-10-2018 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SMART SM00873 100 259 1.7E-19 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SUPERFAMILY SSF46955 281 352 7.87E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Gene3D G3DSA:3.30.56.10 1 80 5.4E-23 T 23-10-2018 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 Pfam PF01409 tRNA synthetases class II core domain (F) 327 555 1.1E-4 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L14_04220 d46e7a91f7a7a90420abbebe630238cb 568 SMART SM00874 280 348 6.6E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L14_08065 9c1fd41c753b7ba93a282010e9f73dbd 483 Gene3D G3DSA:3.40.190.10 88 315 3.5E-32 T 23-10-2018 A3L14_08065 9c1fd41c753b7ba93a282010e9f73dbd 483 SUPERFAMILY SSF53850 71 321 1.15E-37 T 23-10-2018 A3L14_08065 9c1fd41c753b7ba93a282010e9f73dbd 483 Gene3D G3DSA:3.40.190.10 153 272 3.5E-32 T 23-10-2018 A3L14_08065 9c1fd41c753b7ba93a282010e9f73dbd 483 Pfam PF13416 Bacterial extracellular solute-binding protein 90 320 3.5E-16 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L14_03785 09c0b436685b167e49734e3d27c47592 410 SUPERFAMILY SSF46785 200 271 2.06E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_03785 09c0b436685b167e49734e3d27c47592 410 SUPERFAMILY SSF52540 14 143 4.65E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_03785 09c0b436685b167e49734e3d27c47592 410 Pfam PF01022 Bacterial regulatory protein, arsR family 210 256 2.2E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_09075 579ac2102bee87008cf233e1b0730fe1 447 Gene3D G3DSA:3.40.50.10180 23 268 4.8E-161 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 A3L14_09075 579ac2102bee87008cf233e1b0730fe1 447 Gene3D G3DSA:3.40.1480.10 269 432 4.8E-161 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily A3L14_09075 579ac2102bee87008cf233e1b0730fe1 447 Pfam PF13660 Domain of unknown function (DUF4147) 7 244 3.7E-79 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A3L14_09075 579ac2102bee87008cf233e1b0730fe1 447 SUPERFAMILY SSF82544 3 435 1.7E-134 T 23-10-2018 A3L14_09075 579ac2102bee87008cf233e1b0730fe1 447 Pfam PF05161 MOFRL family 325 428 9.3E-34 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 A3L14_03245 abe72108e684d2e5609f275b8e64e5b5 393 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 7 380 3.0E-157 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L14_03245 abe72108e684d2e5609f275b8e64e5b5 393 SUPERFAMILY SSF53448 54 179 1.77E-5 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03245 abe72108e684d2e5609f275b8e64e5b5 393 Gene3D G3DSA:3.90.550.10 1 393 1.6E-158 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_03245 abe72108e684d2e5609f275b8e64e5b5 393 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 381 4.5E-180 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 Gene3D G3DSA:3.50.50.60 5 299 1.6E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 SUPERFAMILY SSF51905 5 341 2.16E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 Gene3D G3DSA:3.50.50.60 124 258 1.6E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 300 1.3E-35 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 5.0E-23 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 5.0E-23 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.0E-23 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 5.0E-23 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 5.0E-23 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.7E-17 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 1.7E-17 T 23-10-2018 A3L14_10715 ecae5600217b081c856ca26247cb3bb5 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 1.7E-17 T 23-10-2018 A3L14_11105 9ec4ed355982b3abed3fbc05e992e62a 184 SUPERFAMILY SSF53639 3 181 3.53E-55 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_11105 9ec4ed355982b3abed3fbc05e992e62a 184 Gene3D G3DSA:3.40.225.10 1 184 5.7E-60 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L14_11105 9ec4ed355982b3abed3fbc05e992e62a 184 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 179 6.6E-49 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L14_11105 9ec4ed355982b3abed3fbc05e992e62a 184 SMART SM01007 6 180 1.1E-59 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L14_00855 17b04ef18ae45ff639d12334be3a67c4 282 SUPERFAMILY SSF103481 34 138 1.1E-14 T 23-10-2018 A3L14_00855 17b04ef18ae45ff639d12334be3a67c4 282 SUPERFAMILY SSF103481 183 275 1.7E-12 T 23-10-2018 A3L14_00855 17b04ef18ae45ff639d12334be3a67c4 282 Pfam PF00892 EamA-like transporter family 149 275 8.1E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_00855 17b04ef18ae45ff639d12334be3a67c4 282 Pfam PF00892 EamA-like transporter family 5 136 6.0E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.9E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.9E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.9E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 SUPERFAMILY SSF54909 67 144 4.65E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_04800 266847e222f27694cfe66c505e4f3903 153 Gene3D G3DSA:1.10.10.10 5 58 9.2E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_04800 266847e222f27694cfe66c505e4f3903 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 2.9E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_04800 266847e222f27694cfe66c505e4f3903 153 Gene3D G3DSA:3.30.70.920 59 148 2.6E-21 T 23-10-2018 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 SUPERFAMILY SSF46785 7 76 1.43E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04800 266847e222f27694cfe66c505e4f3903 153 SMART SM00344 7 113 8.6E-42 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L14_04800 266847e222f27694cfe66c505e4f3903 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 1.6E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L14_06940 a31aaee66f51fa1f1626609dd18590f6 196 SUPERFAMILY SSF55469 14 195 3.83E-39 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_06940 a31aaee66f51fa1f1626609dd18590f6 196 Gene3D G3DSA:3.40.109.10 1 194 8.0E-77 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L14_06940 a31aaee66f51fa1f1626609dd18590f6 196 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 35 190 7.5E-51 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain A3L14_06940 a31aaee66f51fa1f1626609dd18590f6 196 Pfam PF00881 Nitroreductase family 20 192 7.4E-35 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L14_00100 4a99ecae0b49c91c9c2cdcb863c8b173 1297 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1226 518.275 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_00100 4a99ecae0b49c91c9c2cdcb863c8b173 1297 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 8 1205 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_00100 4a99ecae0b49c91c9c2cdcb863c8b173 1297 PIRSF PIRSF016275 1 1213 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_00100 4a99ecae0b49c91c9c2cdcb863c8b173 1297 Pfam PF03833 DNA polymerase II large subunit DP2 12 962 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L14_02615 b9c9d1d56b57251c9e9ea30acd2ec8bc 193 Gene3D G3DSA:3.40.50.300 2 177 1.9E-44 T 23-10-2018 A3L14_02615 b9c9d1d56b57251c9e9ea30acd2ec8bc 193 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 1.4E-62 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L14_02615 b9c9d1d56b57251c9e9ea30acd2ec8bc 193 Pfam PF13189 Cytidylate kinase-like family 7 160 1.4E-24 T 23-10-2018 A3L14_02615 b9c9d1d56b57251c9e9ea30acd2ec8bc 193 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.899 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L14_02615 b9c9d1d56b57251c9e9ea30acd2ec8bc 193 SUPERFAMILY SSF52540 3 176 3.56E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02345 34aa5b8225881df052b26f4f8d9f1225 281 PIRSF PIRSF004961 1 281 4.3E-122 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A3L14_02345 34aa5b8225881df052b26f4f8d9f1225 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 6.0E-75 T 23-10-2018 A3L14_02345 34aa5b8225881df052b26f4f8d9f1225 281 Pfam PF01026 TatD related DNase 5 275 6.5E-31 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L14_02345 34aa5b8225881df052b26f4f8d9f1225 281 Gene3D G3DSA:3.20.20.140 3 280 9.6E-28 T 23-10-2018 A3L14_02345 34aa5b8225881df052b26f4f8d9f1225 281 SUPERFAMILY SSF51556 1 278 1.51E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_02735 61555e23d6d85d2527b4cc50fdf8b24a 99 Pfam PF04930 FUN14 family 12 96 4.4E-13 T 23-10-2018 IPR007014 FUN14 A3L14_09890 fbc0697632d6c38f73f443013023079f 351 SUPERFAMILY SSF53335 165 285 4.28E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_09890 fbc0697632d6c38f73f443013023079f 351 Gene3D G3DSA:1.10.10.10 1 83 2.9E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09890 fbc0697632d6c38f73f443013023079f 351 Gene3D G3DSA:3.40.50.150 101 326 1.2E-85 T 23-10-2018 A3L14_09890 fbc0697632d6c38f73f443013023079f 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.482 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L14_09890 fbc0697632d6c38f73f443013023079f 351 Pfam PF01861 Protein of unknown function DUF43 106 350 8.9E-122 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A3L14_09890 fbc0697632d6c38f73f443013023079f 351 PIRSF PIRSF005895 1 351 3.0E-159 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L14_10500 76372e9e70a6735a563b32f0a9a214d6 283 Pfam PF05681 Fumarate hydratase (Fumerase) 3 270 3.8E-93 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L14_10500 76372e9e70a6735a563b32f0a9a214d6 283 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 2 272 4.6E-115 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 9.7E-117 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 5.6E-50 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.542 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 Gene3D G3DSA:3.40.1370.10 1 255 1.3E-99 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_02480 c6dd96f00039ca5628c8434677b77102 255 SUPERFAMILY SSF52166 1 252 7.72E-73 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 SUPERFAMILY SSF51905 131 267 1.36E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 Gene3D G3DSA:3.50.50.60 5 262 5.3E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 232 1.2E-21 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 Gene3D G3DSA:3.50.50.60 113 220 5.3E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.1E-21 T 23-10-2018 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 212 228 2.1E-21 T 23-10-2018 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.1E-21 T 23-10-2018 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 2.1E-21 T 23-10-2018 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 2.2E-10 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 154 2.2E-10 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.2E-10 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 235 2.2E-10 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L14_06205 3f7aff8a3bf6a126898dfd1694eb68ea 274 SUPERFAMILY SSF51905 4 173 2.16E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_06190 92146daad392f14feadd98f135488fba 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 311 5.5E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_06190 92146daad392f14feadd98f135488fba 348 SUPERFAMILY SSF51971 14 270 1.12E-54 T 23-10-2018 A3L14_06190 92146daad392f14feadd98f135488fba 348 Gene3D G3DSA:3.50.50.60 14 149 4.6E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_06190 92146daad392f14feadd98f135488fba 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 1.2E-15 T 23-10-2018 A3L14_06190 92146daad392f14feadd98f135488fba 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 1.2E-15 T 23-10-2018 A3L14_06190 92146daad392f14feadd98f135488fba 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 1.2E-15 T 23-10-2018 A3L14_06190 92146daad392f14feadd98f135488fba 348 Gene3D G3DSA:3.50.50.60 150 269 1.4E-16 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_02145 a704751fe4dfbfe1f7696891f6cc54a3 111 SUPERFAMILY SSF52980 3 71 6.65E-9 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Pfam PF01011 PQQ enzyme repeat 468 501 5.9E-7 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SUPERFAMILY SSF50998 30 349 4.0E-41 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SUPERFAMILY SSF50998 230 636 2.16E-64 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 523 561 0.86 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 563 601 6.1E-5 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 196 235 5.6 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 603 640 0.96 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 404 441 1.7 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 285 321 20.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 483 521 0.36 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 443 481 0.0023 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 364 402 0.018 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 28 68 34.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 70 107 0.018 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 109 155 63.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 157 194 1.8 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00320 245 283 30.0 T 23-10-2018 IPR001680 WD40 repeat GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Gene3D G3DSA:2.40.128.630 143 248 1.5E-10 T 23-10-2018 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Gene3D G3DSA:2.130.10.10 253 494 2.0E-32 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 380 412 3.3 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 126 165 37.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 499 531 43.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 420 451 25.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 459 491 7.2E-4 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 579 611 1.5 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 174 204 12.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 87 117 9.4 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 213 245 250.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 540 571 2.4 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 45 78 40.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 SMART SM00564 334 372 430.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Pfam PF13360 PQQ-like domain 517 631 1.1E-8 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Pfam PF13360 PQQ-like domain 316 459 5.1E-11 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Pfam PF13360 PQQ-like domain 108 245 5.0E-8 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 770 788 6.3E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Gene3D G3DSA:2.130.10.10 20 142 1.0E-13 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L14_02920 7cdd3883fc0766eaf3b6952002e6046c 790 Gene3D G3DSA:2.130.10.10 495 653 3.9E-22 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L14_05400 082ee49d2576d8314190c996f04b7449 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 332 4.6E-40 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L14_00200 ae2a9f0eb56ee00e4ebcd57b3767338d 101 SUPERFAMILY SSF160363 4 93 1.09E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L14_00200 ae2a9f0eb56ee00e4ebcd57b3767338d 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 9.0E-39 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L14_00200 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 6.7E-38 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L14_00200 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Gene3D G3DSA:3.30.70.1340 1 86 1.2E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L14_10045 9ef00e059275759cb13e089f3c4f4146 194 SUPERFAMILY SSF53323 2 192 9.55E-28 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_10045 9ef00e059275759cb13e089f3c4f4146 194 Gene3D G3DSA:3.40.920.10 1 194 2.2E-33 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_10045 9ef00e059275759cb13e089f3c4f4146 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 1.1E-33 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_01180 f4573ddf7d6f7c8e0ddcb71a5492707f 84 Pfam PF14076 Domain of unknown function (DUF4258) 7 70 1.5E-12 T 23-10-2018 IPR025354 Protein of unknown function DUF4258 A3L14_09245 ac480793bd490b34934de2638d89225e 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 7.5E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L14_09245 ac480793bd490b34934de2638d89225e 382 Gene3D G3DSA:3.30.360.10 216 319 3.0E-135 T 23-10-2018 A3L14_09245 ac480793bd490b34934de2638d89225e 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 110 211 6.9E-10 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L14_09245 ac480793bd490b34934de2638d89225e 382 SUPERFAMILY SSF55347 211 316 2.49E-28 T 23-10-2018 A3L14_09245 ac480793bd490b34934de2638d89225e 382 Gene3D G3DSA:3.40.50.720 3 354 3.0E-135 T 23-10-2018 A3L14_09245 ac480793bd490b34934de2638d89225e 382 PIRSF PIRSF015578 1 379 2.7E-96 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L14_09245 ac480793bd490b34934de2638d89225e 382 SUPERFAMILY SSF51735 1 379 4.17E-74 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 PIRSF PIRSF000915 4 266 1.6E-65 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 Gene3D G3DSA:3.40.50.1000 72 188 2.3E-95 T 23-10-2018 IPR023214 HAD superfamily A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 Pfam PF13242 HAD-hyrolase-like 188 260 6.7E-20 T 23-10-2018 A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 Gene3D G3DSA:3.40.50.1000 8 253 2.3E-95 T 23-10-2018 IPR023214 HAD superfamily A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 SUPERFAMILY SSF56784 7 261 2.1E-69 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 236 3.3E-49 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L14_01065 19ea4f321722eccd09ddca88d0d69c2f 272 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 6.3E-28 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L14_10160 d73df3725c6d798d93455d24926f7767 338 Gene3D G3DSA:3.40.50.150 150 337 1.8E-33 T 23-10-2018 A3L14_10160 d73df3725c6d798d93455d24926f7767 338 Pfam PF02475 Met-10+ like-protein 89 266 7.7E-37 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L14_10160 d73df3725c6d798d93455d24926f7767 338 Gene3D G3DSA:3.30.300.110 64 146 5.8E-12 T 23-10-2018 A3L14_10160 d73df3725c6d798d93455d24926f7767 338 SUPERFAMILY SSF53335 88 336 1.73E-44 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_06715 409871d1ae1dffdf69c7694f3ad931d7 288 SUPERFAMILY SSF48239 15 249 1.16E-15 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_06715 409871d1ae1dffdf69c7694f3ad931d7 288 PIRSF PIRSF016175 7 287 3.1E-128 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A3L14_06810 6790dc6cd4797e59bbb73142064f19cd 448 Pfam PF08308 PEGA domain 351 417 2.4E-9 T 23-10-2018 IPR013229 PEGA A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 SUPERFAMILY SSF55979 3 117 1.53E-33 T 23-10-2018 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 2.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 2.0E-40 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 Gene3D G3DSA:3.70.10.10 2 242 2.3E-79 T 23-10-2018 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 1.3E-10 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.703 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 SUPERFAMILY SSF55979 125 247 1.42E-31 T 23-10-2018 A3L14_06885 ee59b821d12369d6915d7c9b85232ff5 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 115 2.4E-18 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L14_00505 8be28b2c2ee80363267ee304ad9d25c3 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 3.5E-19 T 23-10-2018 A3L14_00505 8be28b2c2ee80363267ee304ad9d25c3 232 Gene3D G3DSA:1.10.150.520 14 96 6.2E-37 T 23-10-2018 A3L14_00505 8be28b2c2ee80363267ee304ad9d25c3 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 189 7.5E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L14_00505 8be28b2c2ee80363267ee304ad9d25c3 232 SUPERFAMILY SSF56784 3 223 1.16E-36 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_00505 8be28b2c2ee80363267ee304ad9d25c3 232 Gene3D G3DSA:3.40.50.1000 3 217 6.2E-37 T 23-10-2018 IPR023214 HAD superfamily A3L14_07705 ecb6e41965f88e53fc85feef69b88992 165 SUPERFAMILY SSF88723 14 134 2.8E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_07705 ecb6e41965f88e53fc85feef69b88992 165 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 14 131 9.3E-17 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A3L14_07705 ecb6e41965f88e53fc85feef69b88992 165 Pfam PF13470 PIN domain 14 131 2.1E-14 T 23-10-2018 IPR002716 PIN domain A3L14_04660 d8cc7e5e3ddad04367d1606e1bf759b8 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 8.7E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_04660 d8cc7e5e3ddad04367d1606e1bf759b8 86 Gene3D G3DSA:2.20.25.30 9 86 1.4E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_04660 d8cc7e5e3ddad04367d1606e1bf759b8 86 SUPERFAMILY SSF57829 10 80 1.22E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_04660 d8cc7e5e3ddad04367d1606e1bf759b8 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.2E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_04660 d8cc7e5e3ddad04367d1606e1bf759b8 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 24.916 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_09540 c9c52170f7517b37a8f0d199285dd929 137 Pfam PF04009 Protein of unknown function (DUF356) 5 110 3.2E-34 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L14_09540 c9c52170f7517b37a8f0d199285dd929 137 PIRSF PIRSF006606 3 133 2.9E-44 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 Pfam PF01625 Peptide methionine sulfoxide reductase 11 161 1.4E-58 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 Pfam PF01641 SelR domain 203 320 2.8E-37 T 23-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 SUPERFAMILY SSF51316 198 337 1.83E-47 T 23-10-2018 IPR011057 Mss4-like superfamily A3L14_07260 519db33babd598c369dfdd561ac2e388 338 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 198 330 8.1E-49 T 23-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 158 5.4E-57 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 SUPERFAMILY SSF55068 7 171 2.22E-69 T 23-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 Gene3D G3DSA:3.30.1060.10 2 166 5.8E-64 T 23-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 8 167 35.946 T 23-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A3L14_07260 519db33babd598c369dfdd561ac2e388 338 Gene3D G3DSA:2.170.150.20 193 338 2.2E-46 T 23-10-2018 A3L14_06825 d165440fd89c4589d24b5260db27ab99 182 SMART SM01022 1 102 4.2E-19 T 23-10-2018 IPR007374 ASCH domain A3L14_06825 d165440fd89c4589d24b5260db27ab99 182 Pfam PF04266 ASCH domain 5 101 1.0E-20 T 23-10-2018 IPR007374 ASCH domain A3L14_06825 d165440fd89c4589d24b5260db27ab99 182 SUPERFAMILY SSF88697 4 101 2.11E-19 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_02840 2bb4c4bfead60b0ab16a146231cfa5d6 292 Pfam PF01875 Memo-like protein 6 289 9.2E-71 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L14_02840 2bb4c4bfead60b0ab16a146231cfa5d6 292 Hamap MF_00055 MEMO1 family protein . 2 291 59.126 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L14_02840 2bb4c4bfead60b0ab16a146231cfa5d6 292 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 4 290 8.1E-88 T 23-10-2018 A3L14_02840 2bb4c4bfead60b0ab16a146231cfa5d6 292 Gene3D G3DSA:3.40.830.10 2 291 3.7E-66 T 23-10-2018 A3L14_10110 a31696cb6e10d35f1051e66faacf25d8 125 Gene3D G3DSA:2.30.130.30 9 108 1.7E-31 T 23-10-2018 A3L14_10110 a31696cb6e10d35f1051e66faacf25d8 125 SMART SM01022 12 100 4.4E-4 T 23-10-2018 IPR007374 ASCH domain A3L14_10110 a31696cb6e10d35f1051e66faacf25d8 125 SUPERFAMILY SSF88697 9 117 2.65E-28 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_10110 a31696cb6e10d35f1051e66faacf25d8 125 Pfam PF04266 ASCH domain 14 105 2.8E-10 T 23-10-2018 IPR007374 ASCH domain A3L14_07135 e86ba0c2416fecbcae500f5986cbb9c5 123 Pfam PF13380 CoA binding domain 7 121 2.1E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_07135 e86ba0c2416fecbcae500f5986cbb9c5 123 SMART SM00881 3 95 1.4E-23 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L14_07135 e86ba0c2416fecbcae500f5986cbb9c5 123 SUPERFAMILY SSF51735 6 121 1.81E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L14_07135 e86ba0c2416fecbcae500f5986cbb9c5 123 Gene3D G3DSA:3.40.50.720 3 122 4.1E-41 T 23-10-2018 A3L14_11010 9cf89a2fdc0b2c8593f2b0ca41bccdc5 265 Pfam PF12686 Protein of unknown function (DUF3800) 4 229 4.5E-17 T 23-10-2018 IPR024524 Protein of unknown function DUF3800 A3L14_08505 18611abc98ef45eeef380c5fde7a89ec 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 4.9E-25 T 23-10-2018 A3L14_08505 18611abc98ef45eeef380c5fde7a89ec 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 4.1E-52 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A3L14_08505 18611abc98ef45eeef380c5fde7a89ec 133 SUPERFAMILY SSF54593 1 131 2.26E-34 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L14_08505 18611abc98ef45eeef380c5fde7a89ec 133 Gene3D G3DSA:3.10.180.10 1 132 2.6E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L14_09480 fcfb724df46e4b37d4bc454872b6385b 238 SUPERFAMILY SSF102215 1 235 3.79E-61 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L14_09480 fcfb724df46e4b37d4bc454872b6385b 238 Gene3D G3DSA:3.40.50.10310 1 236 6.2E-65 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L14_09480 fcfb724df46e4b37d4bc454872b6385b 238 Pfam PF02633 Creatinine amidohydrolase 4 234 2.6E-61 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A3L14_07960 4e8a30c6b668a073c82a4c24d2e2ff8a 169 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 4.0E-29 T 23-10-2018 A3L14_07960 4e8a30c6b668a073c82a4c24d2e2ff8a 169 Gene3D G3DSA:3.40.50.1010 24 165 1.5E-8 T 23-10-2018 A3L14_07960 4e8a30c6b668a073c82a4c24d2e2ff8a 169 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 23 164 1.1E-61 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L14_07960 4e8a30c6b668a073c82a4c24d2e2ff8a 169 Pfam PF01936 NYN domain 32 163 9.2E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L14_11070 a0b10dd9f12a4a30cde0514c1877654e 220 Pfam PF12705 PD-(D/E)XK nuclease superfamily 105 215 2.2E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L14_11070 a0b10dd9f12a4a30cde0514c1877654e 220 Gene3D G3DSA:3.90.320.10 16 217 7.8E-25 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L14_10760 92f4c4a2120c99a61eab8f3134022e59 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 90 9.0E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 PRINTS PR00069 Aldo-keto reductase signature 100 118 1.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 PRINTS PR00069 Aldo-keto reductase signature 207 231 1.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 PRINTS PR00069 Aldo-keto reductase signature 132 149 1.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 132 149 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 Gene3D G3DSA:3.20.20.100 5 271 1.4E-89 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 Pfam PF00248 Aldo/keto reductase family 16 268 4.1E-61 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 SUPERFAMILY SSF51430 10 267 1.07E-77 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L14_04540 e0b4a90e9f5896092dcd366b6369593b 273 PIRSF PIRSF000097 2 271 1.9E-39 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L14_00235 1b61f2b46f48193f0f5999b338f87d2e 528 SUPERFAMILY SSF55486 199 439 2.4E-23 T 23-10-2018 A3L14_00235 1b61f2b46f48193f0f5999b338f87d2e 528 Gene3D G3DSA:1.10.390.60 196 433 4.5E-21 T 23-10-2018 A3L14_00235 1b61f2b46f48193f0f5999b338f87d2e 528 Pfam PF01433 Peptidase family M1 domain 275 429 9.0E-13 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A3L14_04275 45525f1763da938f8902e3ae795da133 97 SUPERFAMILY SSF46785 1 95 2.34E-34 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04275 45525f1763da938f8902e3ae795da133 97 Gene3D G3DSA:2.20.28.10 1 97 3.4E-33 T 23-10-2018 A3L14_09115 87a904ea7d2f29e3c1cec3a1eb622f27 380 Gene3D G3DSA:3.90.550.10 1 258 3.2E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_09115 87a904ea7d2f29e3c1cec3a1eb622f27 380 SUPERFAMILY SSF53448 3 373 4.08E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_09115 87a904ea7d2f29e3c1cec3a1eb622f27 380 Pfam PF00535 Glycosyl transferase family 2 5 136 5.6E-8 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_09515 60a2ca23954317360e15aec7c73c4c29 152 Gene3D G3DSA:3.40.50.1010 1 129 2.9E-6 T 23-10-2018 A3L14_09515 60a2ca23954317360e15aec7c73c4c29 152 SUPERFAMILY SSF88723 1 138 1.4E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_09515 60a2ca23954317360e15aec7c73c4c29 152 Pfam PF01850 PIN domain 3 122 2.4E-8 T 23-10-2018 IPR002716 PIN domain A3L14_04710 130cd22a84df16c866e384a3269de716 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 1.1E-33 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L14_04710 130cd22a84df16c866e384a3269de716 153 PIRSF PIRSF018748 1 153 6.8E-55 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 Pfam PF07549 SecD/SecF GG Motif 28 53 4.1E-4 T 23-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 Pfam PF02355 Protein export membrane protein 330 490 5.5E-18 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 SUPERFAMILY SSF82866 298 492 4.97E-24 T 23-10-2018 A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 18.858 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 Gene3D G3DSA:1.20.1640.10 313 501 7.9E-13 T 23-10-2018 A3L14_00685 e9c532fc7270c05cdc7d11dd086f1a19 507 Gene3D G3DSA:3.30.70.3400 35 117 3.0E-8 T 23-10-2018 A3L14_05795 d48d98023a469d87538f62c79a46e27b 178 Gene3D G3DSA:2.40.380.10 16 166 1.2E-12 T 23-10-2018 IPR035930 FomD-like superfamily A3L14_05795 d48d98023a469d87538f62c79a46e27b 178 SUPERFAMILY SSF159234 5 164 1.7E-38 T 23-10-2018 IPR035930 FomD-like superfamily A3L14_05795 d48d98023a469d87538f62c79a46e27b 178 Pfam PF04167 Protein of unknown function (DUF402) 58 123 1.9E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 Pfam PF00801 PKD domain 851 910 2.9E-14 T 23-10-2018 IPR000601 PKD domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 Pfam PF00801 PKD domain 760 825 8.6E-15 T 23-10-2018 IPR000601 PKD domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SUPERFAMILY SSF49299 837 921 2.22E-23 T 23-10-2018 IPR035986 PKD domain superfamily A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SMART SM00089 666 750 1.9E-5 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SMART SM00089 841 923 3.4E-24 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SMART SM00089 754 836 2.4E-24 T 23-10-2018 IPR022409 PKD/Chitinase domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SUPERFAMILY SSF69318 46 330 1.07E-19 T 23-10-2018 A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SUPERFAMILY SSF49299 662 748 1.14E-12 T 23-10-2018 IPR035986 PKD domain superfamily A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 Gene3D G3DSA:2.60.40.10 749 835 2.4E-26 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 Gene3D G3DSA:2.60.40.10 836 924 1.4E-26 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 Gene3D G3DSA:2.60.40.10 658 748 8.4E-14 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 980 999 4.3E-6 T 23-10-2018 IPR027552 CGP-CTERM domain A3L14_03210 4cd3f82f34a6f81f21dad58259461b20 999 SUPERFAMILY SSF49299 750 835 8.24E-24 T 23-10-2018 IPR035986 PKD domain superfamily A3L14_00970 f216621af1b5b40d9527ab5cc75dc7b7 120 Gene3D G3DSA:3.30.70.3250 1 120 3.5E-50 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L14_00970 f216621af1b5b40d9527ab5cc75dc7b7 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 27.066 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L14_00970 f216621af1b5b40d9527ab5cc75dc7b7 120 SUPERFAMILY SSF160350 4 116 2.09E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L14_00970 f216621af1b5b40d9527ab5cc75dc7b7 120 PIRSF PIRSF004952 4 120 7.3E-47 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A3L14_00970 f216621af1b5b40d9527ab5cc75dc7b7 120 Pfam PF01900 Rpp14/Pop5 family 17 113 2.4E-22 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L14_05240 420a7be442d6958bcef3e7dfad547103 84 SMART SM00966 4 48 2.9E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_05240 420a7be442d6958bcef3e7dfad547103 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 42 4.5E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_05240 420a7be442d6958bcef3e7dfad547103 84 SUPERFAMILY SSF89447 3 44 3.01E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_05240 420a7be442d6958bcef3e7dfad547103 84 Gene3D G3DSA:2.10.260.10 3 47 3.4E-13 T 23-10-2018 A3L14_05240 420a7be442d6958bcef3e7dfad547103 84 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 44 3.9E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_00080 c8468af6611ec14fc730391a31a829f8 355 Gene3D G3DSA:3.40.1610.10 8 221 5.0E-46 T 23-10-2018 IPR027479 Protein of unknown function DUF917, N-terminal A3L14_00080 c8468af6611ec14fc730391a31a829f8 355 Pfam PF06032 Protein of unknown function (DUF917) 14 349 1.7E-88 T 23-10-2018 IPR010318 Protein of unknown function DUF917 A3L14_00080 c8468af6611ec14fc730391a31a829f8 355 SUPERFAMILY SSF160991 9 349 1.83E-80 T 23-10-2018 A3L14_11140 0a75424d447aeb53909259812e806dd5 249 Gene3D G3DSA:3.30.930.10 8 249 2.4E-63 T 23-10-2018 A3L14_11140 0a75424d447aeb53909259812e806dd5 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 158 3.3E-14 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L14_11140 0a75424d447aeb53909259812e806dd5 249 SUPERFAMILY SSF55681 1 246 5.28E-69 T 23-10-2018 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 SUPERFAMILY SSF55154 2 172 4.09E-36 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 SMART SM01118 1 175 5.8E-23 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 Gene3D G3DSA:2.40.320.10 1 180 2.3E-56 T 23-10-2018 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 174 6.4E-45 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 Pfam PF01928 CYTH domain 1 169 7.5E-35 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L14_04005 2876722f5705b4e4500a98b9250e3954 184 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 132 4.0E-59 T 23-10-2018 A3L14_09370 e8ab624a0e795d8c6fb4deb20c8c8b18 81 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.3E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L14_09370 e8ab624a0e795d8c6fb4deb20c8c8b18 81 SUPERFAMILY SSF54909 2 76 4.42E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L14_09370 e8ab624a0e795d8c6fb4deb20c8c8b18 81 Gene3D G3DSA:3.30.70.920 1 73 2.0E-20 T 23-10-2018 A3L14_06580 242b34b5147f3ecc4e4ee797e33384b7 264 SUPERFAMILY SSF52540 5 228 1.64E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06580 242b34b5147f3ecc4e4ee797e33384b7 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_06580 242b34b5147f3ecc4e4ee797e33384b7 264 Pfam PF00005 ABC transporter 20 165 8.1E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_06580 242b34b5147f3ecc4e4ee797e33384b7 264 Gene3D G3DSA:3.40.50.300 2 240 2.1E-62 T 23-10-2018 A3L14_06580 242b34b5147f3ecc4e4ee797e33384b7 264 SMART SM00382 28 222 1.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_05660 857c803b4aafc4a2ca031530e9ea99b2 257 SMART SM00849 33 224 2.8E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_05660 857c803b4aafc4a2ca031530e9ea99b2 257 Gene3D G3DSA:3.60.15.10 6 244 2.5E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_05660 857c803b4aafc4a2ca031530e9ea99b2 257 Pfam PF00753 Metallo-beta-lactamase superfamily 34 224 7.7E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L14_05660 857c803b4aafc4a2ca031530e9ea99b2 257 SUPERFAMILY SSF56281 17 240 1.06E-31 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 SUPERFAMILY SSF116726 103 182 6.41E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 Gene3D G3DSA:1.20.58.220 1 110 5.8E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 SUPERFAMILY SSF109755 2 98 8.5E-16 T 23-10-2018 A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 Pfam PF01895 PhoU domain 11 94 5.3E-9 T 23-10-2018 IPR026022 PhoU domain A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 Pfam PF02080 TrkA-C domain 118 176 3.6E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L14_08135 488f8da89ae14fba7afcd13e3a8a4fa4 191 Gene3D G3DSA:3.30.70.1450 111 190 1.3E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 SMART SM00987 31 185 1.1E-37 T 23-10-2018 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 SMART SM00986 31 185 1.1E-37 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 Gene3D G3DSA:3.40.470.10 5 191 2.6E-71 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 SUPERFAMILY SSF52141 7 191 1.34E-61 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 Pfam PF03167 Uracil DNA glycosylase superfamily 31 184 4.6E-47 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L14_10855 575979447af84ccb39f83aba1eb05518 195 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 1.4E-75 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A3L14_01285 dbe851bf19eae340a7f10f46755bf7fc 152 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 1 129 6.0E-22 T 23-10-2018 A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 Pfam PF03099 Biotin/lipoate A/B protein ligase family 18 121 2.2E-18 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 SUPERFAMILY SSF55681 7 176 4.62E-48 T 23-10-2018 A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 Gene3D G3DSA:3.30.930.10 10 188 1.4E-53 T 23-10-2018 A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 SUPERFAMILY SSF50037 192 237 9.16E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 12 237 2.8E-54 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L14_07500 2cb78b3c9c438b350237c81e126f6c79 239 Gene3D G3DSA:2.30.30.100 192 239 3.3E-9 T 23-10-2018 A3L14_11380 0d45adddbe1efc4d34ae89ac99d7c2b6 392 Pfam PF07282 Putative transposase DNA-binding domain 290 356 2.5E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_11380 0d45adddbe1efc4d34ae89ac99d7c2b6 392 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 5.6E-24 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_11380 0d45adddbe1efc4d34ae89ac99d7c2b6 392 SUPERFAMILY SSF75712 273 343 1.7E-11 T 23-10-2018 A3L14_11380 0d45adddbe1efc4d34ae89ac99d7c2b6 392 Pfam PF01385 Probable transposase 170 259 3.7E-6 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_02605 f285f18d93aadbf77a427419b858e915 175 Pfam PF01956 Integral membrane protein DUF106 12 173 5.3E-30 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L14_02605 f285f18d93aadbf77a427419b858e915 175 SMART SM01415 10 174 7.8E-24 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L14_10730 9c4bba9efef15eb3d7c3f4328400db4e 579 SUPERFAMILY SSF48239 369 566 1.94E-8 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_10730 9c4bba9efef15eb3d7c3f4328400db4e 579 SUPERFAMILY SSF48239 36 341 6.91E-10 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_05610 b6331140408e962799f10b1375b0b426 64 Gene3D G3DSA:1.10.1660.10 7 60 4.5E-10 T 23-10-2018 A3L14_05610 b6331140408e962799f10b1375b0b426 64 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 57 1.1E-12 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A3L14_05610 b6331140408e962799f10b1375b0b426 64 Pfam PF12728 Helix-turn-helix domain 9 58 9.6E-13 T 23-10-2018 A3L14_05610 b6331140408e962799f10b1375b0b426 64 SUPERFAMILY SSF46955 9 57 1.53E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L14_00455 79e1bae93790e19d620670762738fd19 144 Gene3D G3DSA:2.160.10.10 5 141 2.4E-33 T 23-10-2018 A3L14_00455 79e1bae93790e19d620670762738fd19 144 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 85 113 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A3L14_00455 79e1bae93790e19d620670762738fd19 144 SUPERFAMILY SSF51161 3 139 8.87E-36 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L14_00455 79e1bae93790e19d620670762738fd19 144 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 77 110 1.7E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_04810 2b96c34ac94cbb51d2bf2d015d739e74 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L14_04810 2b96c34ac94cbb51d2bf2d015d739e74 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 430 1.8E-98 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L14_04810 2b96c34ac94cbb51d2bf2d015d739e74 433 Pfam PF00860 Permease family 24 400 5.2E-96 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L14_06870 9d267b3c6a20721b4a1babf00d322fe3 419 SUPERFAMILY SSF52540 11 148 2.0E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04155 ffcd006b3bceed830a174c735f34d5da 268 Gene3D G3DSA:3.20.20.150 1 256 6.9E-25 T 23-10-2018 A3L14_04155 ffcd006b3bceed830a174c735f34d5da 268 SUPERFAMILY SSF51658 11 238 3.93E-26 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L14_04155 ffcd006b3bceed830a174c735f34d5da 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 2.5E-15 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L14_00800 e6a61cf7f90ce738deca07ec129a2b62 485 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 55 2.8E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L14_00800 e6a61cf7f90ce738deca07ec129a2b62 485 Gene3D G3DSA:1.10.3720.10 269 484 1.2E-23 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00800 e6a61cf7f90ce738deca07ec129a2b62 485 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 297 484 5.6E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00800 e6a61cf7f90ce738deca07ec129a2b62 485 SUPERFAMILY SSF161098 273 466 5.49E-25 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 SMART SM00709 14 174 2.6E-75 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 Gene3D G3DSA:2.20.25.420 3 59 1.4E-7 T 23-10-2018 A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 15 205 1.3E-61 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 Pfam PF03367 ZPR1 zinc-finger domain 15 171 7.4E-38 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 Gene3D G3DSA:2.60.120.1040 63 187 3.3E-21 T 23-10-2018 A3L14_02215 0ab4cd54b776d7e92bdf82f80743da5c 208 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 16 181 1.8E-69 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A3L14_10825 e609516a29372a86ac3866f5eaaa305d 262 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 205 6.5E-12 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L14_10825 e609516a29372a86ac3866f5eaaa305d 262 SUPERFAMILY SSF52540 2 227 3.46E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10825 e609516a29372a86ac3866f5eaaa305d 262 Gene3D G3DSA:3.40.50.300 1 227 7.8E-41 T 23-10-2018 A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 1.0E-34 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 SUPERFAMILY SSF54893 3 98 7.06E-33 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.088 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 3.7E-19 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 SUPERFAMILY SSF57825 100 148 9.03E-16 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 148 2.3E-60 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 Gene3D G3DSA:2.30.30.20 98 151 7.0E-23 T 23-10-2018 A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 96 2.7E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L14_10330 56eb56176e7554b37006e1de8f819d75 151 Gene3D G3DSA:3.30.70.140 1 97 3.9E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L14_00005 290e870d2dcedd3f15f950832de7ff5c 170 Hamap MF_01117 CDP-archaeol synthase [carS]. 13 170 27.801 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L14_00005 290e870d2dcedd3f15f950832de7ff5c 170 Pfam PF01864 CDP-archaeol synthase 6 170 9.8E-59 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L14_11155 119837be507e5be5f5ebe6df602f4ccb 187 PIRSF PIRSF006006 1 178 4.2E-85 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L14_11155 119837be507e5be5f5ebe6df602f4ccb 187 Pfam PF04407 Protein of unknown function (DUF531) 1 169 1.2E-77 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 Pfam PF02803 Thiolase, C-terminal domain 258 355 2.2E-10 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 SUPERFAMILY SSF53901 4 229 1.35E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 Gene3D G3DSA:3.40.47.10 4 385 7.2E-122 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 SUPERFAMILY SSF53901 247 373 2.97E-28 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 PIRSF PIRSF000429 1 383 1.1E-64 T 23-10-2018 IPR002155 Thiolase GO:0016747 A3L14_09570 f182d1de79b39c3e2f6d1960be8af54d 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 4.6E-26 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 Gene3D G3DSA:1.10.340.30 40 153 3.0E-63 T 23-10-2018 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 ProSitePatterns PS01155 Endonuclease III family signature. 123 152 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 SMART SM00525 208 228 2.7E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 190 1.2E-17 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 SUPERFAMILY SSF48150 24 228 1.38E-62 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 Pfam PF00633 Helix-hairpin-helix motif 120 149 3.1E-7 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 Gene3D G3DSA:1.10.1670.10 35 225 3.0E-63 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 Hamap MF_00942 Endonuclease III [nth]. 21 231 33.245 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 PIRSF PIRSF001435 19 232 8.3E-42 T 23-10-2018 A3L14_08130 270a9463ff56a5c3b11482b1a0bbd953 243 SMART SM00478 57 207 4.3E-57 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L14_05570 c5e04a18db922a9073ac8c4915a4bdfb 349 Pfam PF00535 Glycosyl transferase family 2 40 199 9.0E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_05570 c5e04a18db922a9073ac8c4915a4bdfb 349 Gene3D G3DSA:3.90.550.10 27 242 8.2E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_05570 c5e04a18db922a9073ac8c4915a4bdfb 349 SUPERFAMILY SSF53448 36 263 4.5E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_08600 bfc4806d60d1615c6a107792a6762c79 234 PIRSF PIRSF005928 10 232 4.1E-102 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A3L14_08600 bfc4806d60d1615c6a107792a6762c79 234 Gene3D G3DSA:3.30.460.10 21 95 3.0E-7 T 23-10-2018 A3L14_08600 bfc4806d60d1615c6a107792a6762c79 234 SUPERFAMILY SSF81301 20 73 7.63E-9 T 23-10-2018 A3L14_08600 bfc4806d60d1615c6a107792a6762c79 234 Pfam PF01909 Nucleotidyltransferase domain 37 79 5.3E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_03995 f673bc4f27ae95682760fad0f3d5d75c 284 Gene3D G3DSA:3.40.50.300 2 277 1.3E-72 T 23-10-2018 A3L14_03995 f673bc4f27ae95682760fad0f3d5d75c 284 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L14_03995 f673bc4f27ae95682760fad0f3d5d75c 284 SMART SM00382 30 227 2.9E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_03995 f673bc4f27ae95682760fad0f3d5d75c 284 Pfam PF00005 ABC transporter 21 178 4.7E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_03995 f673bc4f27ae95682760fad0f3d5d75c 284 SUPERFAMILY SSF52540 3 239 2.88E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_05910 29f90d05689a7c88d02a0245ee052029 75 Gene3D G3DSA:2.30.30.90 12 75 4.2E-22 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A3L14_05910 29f90d05689a7c88d02a0245ee052029 75 SMART SM00899 3 74 4.9E-21 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L14_05910 29f90d05689a7c88d02a0245ee052029 75 Pfam PF04023 FeoA domain 3 73 1.7E-18 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L14_05910 29f90d05689a7c88d02a0245ee052029 75 SUPERFAMILY SSF50037 5 74 5.72E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L14_03325 8aa4eeab9cfba80054f87edfdb00af36 59 Pfam PF08279 HTH domain 7 49 3.0E-5 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L14_03325 8aa4eeab9cfba80054f87edfdb00af36 59 Gene3D G3DSA:1.10.10.10 4 56 1.5E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_03325 8aa4eeab9cfba80054f87edfdb00af36 59 SUPERFAMILY SSF46785 5 56 3.85E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08390 9e0e3fe9ad38db5487dc379873b25008 121 Gene3D G3DSA:1.20.120.330 1 120 4.2E-31 T 23-10-2018 A3L14_08390 9e0e3fe9ad38db5487dc379873b25008 121 Pfam PF05168 HEPN domain 3 114 9.3E-24 T 23-10-2018 IPR007842 HEPN domain A3L14_08390 9e0e3fe9ad38db5487dc379873b25008 121 SUPERFAMILY SSF81593 4 117 5.89E-8 T 23-10-2018 A3L14_01655 05a29fdc0b8f23de9ea4e3cb29acfe2e 264 Pfam PF13649 Methyltransferase domain 43 142 5.1E-8 T 23-10-2018 A3L14_01655 05a29fdc0b8f23de9ea4e3cb29acfe2e 264 SUPERFAMILY SSF53335 22 156 3.25E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_01655 05a29fdc0b8f23de9ea4e3cb29acfe2e 264 Gene3D G3DSA:3.40.50.150 7 177 1.6E-15 T 23-10-2018 A3L14_03460 9baf32ae10a60effc6e0e0b22c644938 429 SUPERFAMILY SSF48537 29 263 6.21E-33 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 A3L14_03460 9baf32ae10a60effc6e0e0b22c644938 429 SMART SM00770 1 254 1.8E-51 T 23-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A3L14_03460 9baf32ae10a60effc6e0e0b22c644938 429 Gene3D G3DSA:1.10.575.10 21 154 2.0E-12 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 A3L14_01570 ab04f51fb7f2ce038d2b844298bdcfc4 169 Pfam PF06510 Protein of unknown function (DUF1102) 46 168 1.9E-33 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L14_04445 2588d29d89028bc53065fcf3240f19b1 459 SUPERFAMILY SSF161070 5 367 7.06E-7 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L14_07640 489cf7de466778181e895d029fcfacad 118 Hamap MF_00674 UPF0251 protein . 14 111 23.523 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L14_07640 489cf7de466778181e895d029fcfacad 118 Pfam PF02001 Protein of unknown function DUF134 13 102 8.3E-25 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L14_07640 489cf7de466778181e895d029fcfacad 118 Gene3D G3DSA:1.10.10.10 47 96 2.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_07640 489cf7de466778181e895d029fcfacad 118 SUPERFAMILY SSF88659 49 95 1.16E-8 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 Gene3D G3DSA:2.30.170.20 2 66 1.3E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 SMART SM00746 7 45 2.2E-12 T 23-10-2018 IPR011017 TRASH domain A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 SUPERFAMILY SSF57716 6 56 8.84E-21 T 23-10-2018 A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 Pfam PF01246 Ribosomal protein L24e 3 60 2.7E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A3L14_07825 3d526b1419cd9e1409461bf5c2ead980 68 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.423 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 165 2.1E-48 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 SUPERFAMILY SSF46785 6 87 4.35E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 SMART SM00531 19 158 2.3E-56 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 Gene3D G3DSA:1.10.10.10 4 87 3.3E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 Pfam PF02002 TFIIE alpha subunit 11 110 2.5E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.514 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L14_10625 96600a101a6715a46eee1ed3621a5997 177 PIRSF PIRSF006373 1 177 6.8E-70 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L14_06890 9ca299288000044e1efb81467777d888 188 Gene3D G3DSA:1.20.58.1030 1 113 5.5E-46 T 23-10-2018 A3L14_06890 9ca299288000044e1efb81467777d888 188 Gene3D G3DSA:3.40.5.50 129 187 1.3E-25 T 23-10-2018 A3L14_03665 6d7686dee29d2140a0f7f5eeece532e4 66 Pfam PF04021 Class III signal peptide 2 27 4.5E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 SUPERFAMILY SSF56104 6 235 6.87E-82 T 23-10-2018 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 Gene3D G3DSA:3.30.470.20 84 219 1.2E-94 T 23-10-2018 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 Gene3D G3DSA:3.30.200.20 22 231 1.2E-94 T 23-10-2018 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 Pfam PF01259 SAICAR synthetase 7 228 2.0E-66 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 225 7.7E-76 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L14_01375 4f0fdf392c976f39086ec62f36dd78d5 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 32.957 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L14_09450 88c49b70b671babb7ea9ba508b89e3bd 500 Pfam PF00361 Proton-conducting membrane transporter 120 396 4.0E-48 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09450 88c49b70b671babb7ea9ba508b89e3bd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 225 249 3.0E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09450 88c49b70b671babb7ea9ba508b89e3bd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 126 145 3.0E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09450 88c49b70b671babb7ea9ba508b89e3bd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 3.0E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_09450 88c49b70b671babb7ea9ba508b89e3bd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 308 327 3.0E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_00320 6f1890a71d3a463564823cfb1ec67a38 164 PIRSF PIRSF019115 1 164 1.2E-65 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L14_00320 6f1890a71d3a463564823cfb1ec67a38 164 Gene3D G3DSA:2.40.50.100 97 163 2.8E-31 T 23-10-2018 A3L14_00320 6f1890a71d3a463564823cfb1ec67a38 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 3 163 6.6E-52 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L14_11240 9e8e981b6a9767aca8f93ab4ea70b620 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 9.0E-22 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L14_05635 a73d1bb11411f520aa9af2a64e91a191 356 Gene3D G3DSA:1.10.443.10 184 347 1.4E-39 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L14_05635 a73d1bb11411f520aa9af2a64e91a191 356 SUPERFAMILY SSF56349 94 336 2.94E-12 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L14_05635 a73d1bb11411f520aa9af2a64e91a191 356 Pfam PF16795 Archaeal phage integrase 188 343 6.2E-44 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal A3L14_11355 b3818816423462b0797796de7374535b 187 Gene3D G3DSA:3.30.460.80 20 145 1.4E-13 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11355 b3818816423462b0797796de7374535b 187 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 46 163 4.7E-20 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11355 b3818816423462b0797796de7374535b 187 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 106 162 2.0E-10 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11355 b3818816423462b0797796de7374535b 187 SUPERFAMILY SSF143243 36 165 7.19E-27 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01270 4d2ab8fc0755326a8b12efb75e86a21f 293 Gene3D G3DSA:3.40.50.300 2 230 1.5E-61 T 23-10-2018 A3L14_01270 4d2ab8fc0755326a8b12efb75e86a21f 293 Pfam PF00005 ABC transporter 19 158 5.6E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_01270 4d2ab8fc0755326a8b12efb75e86a21f 293 SUPERFAMILY SSF52540 3 218 7.5E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01270 4d2ab8fc0755326a8b12efb75e86a21f 293 SMART SM00382 28 214 3.7E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_10795 e2eb88f3bc3039a48e0f7a4e3e7f218f 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 5 188 5.2E-43 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L14_03675 57cf167e0a93e916005ac36e70a9ae9d 198 Pfam PF08745 PINc domain ribonuclease 2 190 2.2E-65 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L14_03675 57cf167e0a93e916005ac36e70a9ae9d 198 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 2.4E-70 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L14_03675 57cf167e0a93e916005ac36e70a9ae9d 198 SUPERFAMILY SSF88723 71 188 1.77E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_03675 57cf167e0a93e916005ac36e70a9ae9d 198 Hamap MF_01078 UPF0278 protein . 1 193 30.1 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L14_03340 11a213783c267c1a2f4b3ad0799483a4 399 Pfam PF00155 Aminotransferase class I and II 31 368 1.8E-58 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L14_03340 11a213783c267c1a2f4b3ad0799483a4 399 Gene3D G3DSA:3.90.1150.10 24 390 1.8E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L14_03340 11a213783c267c1a2f4b3ad0799483a4 399 SUPERFAMILY SSF53383 4 395 3.99E-104 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L14_03340 11a213783c267c1a2f4b3ad0799483a4 399 Gene3D G3DSA:3.40.640.10 53 294 1.8E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L14_03285 43b548e805e11c104b481e53c769f192 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 23 81 6.0E-4 T 23-10-2018 A3L14_03330 872892d4d449562252d22dbca7f67995 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 4.0E-43 T 23-10-2018 IPR005642 Lysine exporter LysO A3L14_03330 872892d4d449562252d22dbca7f67995 193 Pfam PF03956 Lysine exporter LysO 9 190 3.8E-59 T 23-10-2018 IPR005642 Lysine exporter LysO A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 SUPERFAMILY SSF159234 318 469 5.75E-30 T 23-10-2018 IPR035930 FomD-like superfamily A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 33.788 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 Gene3D G3DSA:2.40.380.10 373 471 1.6E-9 T 23-10-2018 IPR035930 FomD-like superfamily A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 Pfam PF04167 Protein of unknown function (DUF402) 379 442 1.5E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 Pfam PF10150 Ribonuclease E/G family 152 263 7.4E-12 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A3L14_10140 ebaed2c3e2bec4fd8dbf07fa96821979 471 PIRSF PIRSF018644 5 471 2.3E-191 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 Gene3D G3DSA:3.40.50.12240 2 459 1.1E-195 T 23-10-2018 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.693 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 SUPERFAMILY SSF50615 5 66 8.24E-5 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 1.9E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 SUPERFAMILY SSF47917 362 420 2.2E-9 T 23-10-2018 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 PIRSF PIRSF039114 1 463 3.2E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 7.6E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 SUPERFAMILY SSF52540 79 355 6.45E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00730 c80dc0a5987c8cc3c561f71810de3b06 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 461 7.9E-268 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A3L14_10425 620dcc5e54e637c301442731084b9e72 220 Gene3D G3DSA:3.40.50.11570 4 215 3.9E-68 T 23-10-2018 A3L14_10425 620dcc5e54e637c301442731084b9e72 220 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 210 1.5E-69 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_08695 9f661a006442433d354d7eb635afb492 76 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 18.105 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_08695 9f661a006442433d354d7eb635afb492 76 Gene3D G3DSA:3.10.20.10 3 75 1.7E-25 T 23-10-2018 A3L14_08695 9f661a006442433d354d7eb635afb492 76 SUPERFAMILY SSF160374 1 74 4.97E-24 T 23-10-2018 A3L14_08695 9f661a006442433d354d7eb635afb492 76 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 57 3.0E-15 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A3L14_08695 9f661a006442433d354d7eb635afb492 76 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 2.8E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_11295 5a33678c1406cb4fffdd448ac91677c5 329 Pfam PF00146 NADH dehydrogenase 13 319 7.1E-60 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_01185 cc91dfb838c51444c6a849d42888eb66 476 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 7.7E-64 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L14_01185 cc91dfb838c51444c6a849d42888eb66 476 SUPERFAMILY SSF53649 15 462 2.32E-41 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L14_01185 cc91dfb838c51444c6a849d42888eb66 476 Gene3D G3DSA:3.40.720.10 4 304 2.0E-51 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L14_10030 5846cb39bb9d84eaa982df81a798b40b 306 SUPERFAMILY SSF56235 18 299 1.18E-86 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L14_10030 5846cb39bb9d84eaa982df81a798b40b 306 Pfam PF01112 Asparaginase 2 297 6.2E-94 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A3L14_10030 5846cb39bb9d84eaa982df81a798b40b 306 Gene3D G3DSA:3.60.20.30 176 302 2.0E-32 T 23-10-2018 A3L14_04435 01e3703ccadc9fd14ab0df4bbc7705a3 412 SUPERFAMILY SSF53756 42 412 1.49E-54 T 23-10-2018 A3L14_04435 01e3703ccadc9fd14ab0df4bbc7705a3 412 Pfam PF00534 Glycosyl transferases group 1 225 391 1.9E-27 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L14_04435 01e3703ccadc9fd14ab0df4bbc7705a3 412 Gene3D G3DSA:3.40.50.2000 201 397 3.6E-161 T 23-10-2018 A3L14_04435 01e3703ccadc9fd14ab0df4bbc7705a3 412 Gene3D G3DSA:3.40.50.2000 14 200 3.6E-161 T 23-10-2018 A3L14_01325 0dfd47d3eeea196aad59f1bffec5c9d5 395 Pfam PF04165 Protein of unknown function (DUF401) 6 384 2.0E-67 T 23-10-2018 IPR007294 Protein of unknown function DUF401 A3L14_01325 0dfd47d3eeea196aad59f1bffec5c9d5 395 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 5 391 2.5E-135 T 23-10-2018 IPR005253 Conserved hypothetical protein CHP00529 A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 261 3.3E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 532 1.4E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 Gene3D G3DSA:1.10.3720.10 286 539 2.1E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 Gene3D G3DSA:1.10.3720.10 6 265 4.7E-62 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 SUPERFAMILY SSF161098 6 258 4.11E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_01935 3dfba3b3f09cdb1cadefb8f021cc20a0 541 SUPERFAMILY SSF161098 288 535 2.51E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_07360 5e19ef3a3d8b5410ad6c1ccb5ac2ef3e 159 SUPERFAMILY SSF47240 1 147 3.58E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_07360 5e19ef3a3d8b5410ad6c1ccb5ac2ef3e 159 Gene3D G3DSA:1.20.1260.10 1 143 4.9E-26 T 23-10-2018 IPR012347 Ferritin-like A3L14_07360 5e19ef3a3d8b5410ad6c1ccb5ac2ef3e 159 Pfam PF02915 Rubrerythrin 5 138 1.2E-15 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_00885 a4df35f4f3127520d96e6a2d8f73648d 102 Gene3D G3DSA:3.30.720.70 1 102 1.3E-45 T 23-10-2018 A3L14_08315 5b3d79355d5635e93e9c2f73ea16c89f 248 Pfam PF05763 Protein of unknown function (DUF835) 129 243 3.6E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_03290 5ea0b4e3318168ead010abcf41f44cb1 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 195 4.0E-61 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 A3L14_03290 5ea0b4e3318168ead010abcf41f44cb1 204 Gene3D G3DSA:1.10.1760.20 1 197 6.2E-64 T 23-10-2018 A3L14_06815 5bbf8880810bc965361fbe884fee9b25 153 Pfam PF06695 Putative small multi-drug export protein 17 143 9.4E-30 T 23-10-2018 IPR009577 Putative small multi-drug export A3L14_05175 85a601b873a370de7fac20ef36091438 186 Gene3D G3DSA:3.30.2170.10 1 140 5.3E-36 T 23-10-2018 A3L14_05175 85a601b873a370de7fac20ef36091438 186 Pfam PF04493 Endonuclease V 14 137 6.8E-32 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L14_05175 85a601b873a370de7fac20ef36091438 186 Pfam PF04493 Endonuclease V 143 179 5.5E-5 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L14_05175 85a601b873a370de7fac20ef36091438 186 Gene3D G3DSA:3.30.2170.10 141 185 8.6E-7 T 23-10-2018 A3L14_02360 3b24c345d1bc32e3d00bdcbf72eba567 219 Gene3D G3DSA:3.40.50.11570 3 217 1.2E-57 T 23-10-2018 A3L14_02360 3b24c345d1bc32e3d00bdcbf72eba567 219 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 213 1.3E-62 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 Pfam PF01769 Divalent cation transporter 56 178 2.0E-22 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 Pfam PF01769 Divalent cation transporter 259 382 2.4E-16 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 SUPERFAMILY SSF161093 220 390 2.62E-25 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 SUPERFAMILY SSF161093 12 184 3.53E-31 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 Gene3D G3DSA:1.10.357.20 10 186 3.2E-11 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L14_08155 55ee3c01bef99c9cb06b46b16babc327 391 Gene3D G3DSA:1.10.357.20 212 390 3.8E-12 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.4E-181 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 Gene3D G3DSA:3.30.260.10 147 405 1.6E-215 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 1.4E-234 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 SUPERFAMILY SSF52029 212 378 1.13E-61 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 SUPERFAMILY SSF48592 17 523 7.98E-91 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.9E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.9E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.9E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.9E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.9E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 Gene3D G3DSA:3.50.7.10 218 369 1.6E-215 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 Gene3D G3DSA:1.10.560.10 28 522 1.6E-215 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L14_06235 3e1b8f0643e23c35fe7840b6369da456 550 SUPERFAMILY SSF54849 149 405 9.46E-32 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L14_05825 71daeefca01fd2c24e2635016c475250 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 19.961 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05825 71daeefca01fd2c24e2635016c475250 63 Gene3D G3DSA:2.20.25.30 1 57 4.6E-20 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_05825 71daeefca01fd2c24e2635016c475250 63 SUPERFAMILY SSF57829 1 56 2.01E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L14_05825 71daeefca01fd2c24e2635016c475250 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 1.0E-15 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05825 71daeefca01fd2c24e2635016c475250 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_05825 71daeefca01fd2c24e2635016c475250 63 Pfam PF01907 Ribosomal protein L37e 3 55 3.7E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_09650 092b325fcc3482a67fb8ab2b5d44b879 146 Pfam PF04024 PspC domain 6 64 3.5E-19 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A3L14_03630 ffd1ff8e63a80df63c26d59722da9434 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 2.8E-18 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_03630 ffd1ff8e63a80df63c26d59722da9434 61 SUPERFAMILY SSF103456 3 58 2.62E-19 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_03630 ffd1ff8e63a80df63c26d59722da9434 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 11.978 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_03630 ffd1ff8e63a80df63c26d59722da9434 61 Gene3D G3DSA:1.20.5.820 1 61 1.0E-22 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_03630 ffd1ff8e63a80df63c26d59722da9434 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 146 2.4E-30 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 Gene3D G3DSA:3.40.50.1450 1 148 8.0E-36 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 PRINTS PR00446 Hydrogen uptake protein signature 15 26 2.7E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 PRINTS PR00446 Hydrogen uptake protein signature 63 79 2.7E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 PRINTS PR00446 Hydrogen uptake protein signature 3 15 2.7E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 PRINTS PR00446 Hydrogen uptake protein signature 51 61 2.7E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 SUPERFAMILY SSF53163 1 148 6.8E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L14_05085 1b0ccf3707056f1c69f8103fc3fcc699 149 Pfam PF01750 Hydrogenase maturation protease 30 144 4.9E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L14_06070 6cbc1af0645e6dd94cd34fd465d397cf 126 Gene3D G3DSA:3.40.50.1010 1 121 7.0E-14 T 23-10-2018 A3L14_06070 6cbc1af0645e6dd94cd34fd465d397cf 126 SUPERFAMILY SSF88723 1 122 9.53E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_06070 6cbc1af0645e6dd94cd34fd465d397cf 126 Pfam PF01850 PIN domain 2 117 1.0E-19 T 23-10-2018 IPR002716 PIN domain A3L14_06070 6cbc1af0645e6dd94cd34fd465d397cf 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 124 9.743 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_07090 5d786b0863eb0d24bd94a4642eb7fa9a 202 SUPERFAMILY SSF55729 11 199 1.13E-22 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_07090 5d786b0863eb0d24bd94a4642eb7fa9a 202 Pfam PF00583 Acetyltransferase (GNAT) family 37 175 5.6E-17 T 23-10-2018 IPR000182 GNAT domain A3L14_07090 5d786b0863eb0d24bd94a4642eb7fa9a 202 Gene3D G3DSA:3.40.630.30 9 201 3.0E-32 T 23-10-2018 A3L14_04835 a1d690a1c2560ef4573180dd437eb304 171 SUPERFAMILY SSF143243 22 160 5.75E-30 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04835 a1d690a1c2560ef4573180dd437eb304 171 Gene3D G3DSA:3.30.460.80 2 126 6.0E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04835 a1d690a1c2560ef4573180dd437eb304 171 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 151 8.3E-26 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04835 a1d690a1c2560ef4573180dd437eb304 171 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 82 123 1.0E-12 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 SUPERFAMILY SSF101821 68 176 1.16E-26 T 23-10-2018 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 Gene3D G3DSA:2.40.30.40 68 160 1.8E-131 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 330 3.6E-97 T 23-10-2018 IPR008007 Peptidase M42 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 SUPERFAMILY SSF53187 4 340 1.58E-62 T 23-10-2018 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 PIRSF PIRSF001123 1 344 9.1E-102 T 23-10-2018 IPR008007 Peptidase M42 A3L14_04015 38a399c89da28328376337fae2f95e6f 345 Gene3D G3DSA:3.40.630.10 7 333 1.8E-131 T 23-10-2018 A3L14_06300 0ea7e9e7d624e139484835068ee4ec98 153 SUPERFAMILY SSF88723 5 144 2.29E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_06300 0ea7e9e7d624e139484835068ee4ec98 153 Pfam PF01850 PIN domain 6 139 2.9E-11 T 23-10-2018 IPR002716 PIN domain A3L14_06300 0ea7e9e7d624e139484835068ee4ec98 153 Gene3D G3DSA:3.40.50.1010 6 139 3.6E-9 T 23-10-2018 A3L14_07910 373d366a149055a7a52804c54267ac92 301 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 184 285 1.0E-41 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L14_07910 373d366a149055a7a52804c54267ac92 301 Pfam PF04659 Archaeal flagella protein 180 273 1.4E-29 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A3L14_07910 373d366a149055a7a52804c54267ac92 301 PIRSF PIRSF017066 123 301 2.2E-61 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L14_07910 373d366a149055a7a52804c54267ac92 301 PIRSF PIRSF017066 1 117 1.5E-18 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A3L14_11200 14173fd6a269d8978184a8a0fa92d62f 405 Pfam PF01384 Phosphate transporter family 21 394 5.8E-112 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L14_06845 e19975a569d21e421d4b1049e20753e8 394 Pfam PF03222 Tryptophan/tyrosine permease family 65 393 3.9E-29 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L14_05690 d80b367794054c0994b8236270a79cdc 333 Pfam PF13421 SPFH domain-Band 7 family 16 204 1.5E-35 T 23-10-2018 IPR033880 SPFH domain, YdjI-like A3L14_05690 d80b367794054c0994b8236270a79cdc 333 SUPERFAMILY SSF117892 75 203 6.02E-13 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L14_05690 d80b367794054c0994b8236270a79cdc 333 Pfam PF12773 Double zinc ribbon 288 329 2.2E-10 T 23-10-2018 IPR025874 Double zinc ribbon A3L14_09060 2961ebdaa6fee9a7bc69f146b36ed637 266 Pfam PF04055 Radical SAM superfamily 29 183 1.0E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_09060 2961ebdaa6fee9a7bc69f146b36ed637 266 SUPERFAMILY SSF102114 31 227 4.32E-8 T 23-10-2018 A3L14_09060 2961ebdaa6fee9a7bc69f146b36ed637 266 Gene3D G3DSA:3.20.20.70 19 255 1.3E-5 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 Pfam PF13086 AAA domain 170 419 7.2E-54 T 23-10-2018 A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 Pfam PF13087 AAA domain 424 624 7.9E-55 T 23-10-2018 A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 Gene3D G3DSA:3.40.50.300 447 655 4.7E-60 T 23-10-2018 A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 14 646 9.8E-246 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 SMART SM00382 184 434 8.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_01305 2d561b5185b65bd45ae2aad8fba66a8f 659 SUPERFAMILY SSF52540 163 637 3.79E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_06040 55cbaeebf2419a6565ce0ddb4ed4ce45 294 Pfam PF03186 CobD/Cbib protein 8 265 2.9E-85 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L14_06040 55cbaeebf2419a6565ce0ddb4ed4ce45 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 287 1.4E-82 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L14_06040 55cbaeebf2419a6565ce0ddb4ed4ce45 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 290 79.437 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L14_00760 be3811874b43fb33e8a4f48f82201fb5 355 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 350 8.7E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00760 be3811874b43fb33e8a4f48f82201fb5 355 Gene3D G3DSA:1.10.3720.10 68 338 2.5E-5 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00760 be3811874b43fb33e8a4f48f82201fb5 355 SUPERFAMILY SSF161098 114 333 1.8E-9 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_08020 c7edd9da2f9049879f6eec7dfcf475e9 253 Pfam PF02361 Cobalt transport protein 11 204 1.1E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L14_10405 dda8ee678baf94b4a13e9a116b263cf9 417 Pfam PF01882 Protein of unknown function DUF58 187 271 1.7E-25 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L14_11320 2acf613b3b638c45e8bb6685bcb7a856 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 80 5.9E-20 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L14_05760 f1e2003d16d77b53c911fc9493854599 145 Pfam PF01850 PIN domain 2 133 1.8E-9 T 23-10-2018 IPR002716 PIN domain A3L14_05760 f1e2003d16d77b53c911fc9493854599 145 SUPERFAMILY SSF88723 1 143 1.71E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_05760 f1e2003d16d77b53c911fc9493854599 145 Gene3D G3DSA:3.40.50.1010 1 136 1.1E-13 T 23-10-2018 A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 Gene3D G3DSA:3.40.50.280 3 123 6.3E-24 T 23-10-2018 A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 Pfam PF04055 Radical SAM superfamily 168 333 3.1E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 SMART SM00729 164 382 4.2E-47 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 Gene3D G3DSA:3.80.30.20 163 390 9.9E-37 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 1.2E-139 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 Pfam PF02310 B12 binding domain 17 112 7.2E-7 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L14_03580 3c6a512dda7fbd8ef2b05aeb2e3af9a6 424 SUPERFAMILY SSF102114 154 377 2.75E-38 T 23-10-2018 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 230 243 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 PRINTS PR00990 Ribokinase signature 200 211 2.2E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 PRINTS PR00990 Ribokinase signature 10 31 2.2E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 PRINTS PR00990 Ribokinase signature 107 120 2.2E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 PRINTS PR00990 Ribokinase signature 168 183 2.2E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 Gene3D G3DSA:3.40.1190.20 4 290 1.7E-60 T 23-10-2018 IPR029056 Ribokinase-like A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 Pfam PF00294 pfkB family carbohydrate kinase 7 275 1.7E-41 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L14_10650 c8ced046b867d0d7752b5d9fd5f09382 298 SUPERFAMILY SSF53613 6 274 1.25E-62 T 23-10-2018 IPR029056 Ribokinase-like A3L14_08395 91111653d54209751c49115b85318a36 202 Gene3D G3DSA:3.30.460.10 71 169 1.8E-11 T 23-10-2018 A3L14_08395 91111653d54209751c49115b85318a36 202 Pfam PF01909 Nucleotidyltransferase domain 81 149 9.0E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_08395 91111653d54209751c49115b85318a36 202 SUPERFAMILY SSF46785 4 92 7.35E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_08395 91111653d54209751c49115b85318a36 202 SUPERFAMILY SSF81301 86 171 4.73E-13 T 23-10-2018 A3L14_08395 91111653d54209751c49115b85318a36 202 Gene3D G3DSA:1.10.10.10 1 70 4.1E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09430 5ca64c2b555794333423577afd8f17d0 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 73 7.8E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L14_10460 ad2aa99e50034b44822b6152f816253a 183 Gene3D G3DSA:3.40.50.620 38 183 3.5E-7 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_10460 ad2aa99e50034b44822b6152f816253a 183 SUPERFAMILY SSF52402 64 180 7.28E-7 T 23-10-2018 A3L14_09300 c89b6f791e69d6512f98095da4e33799 87 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 1.1E-22 T 23-10-2018 IPR001727 Gdt1 family A3L14_06100 37d6f80b6f13cf40002112a262b619b9 65 Gene3D G3DSA:3.40.50.1010 1 53 1.1E-7 T 23-10-2018 A3L14_06100 37d6f80b6f13cf40002112a262b619b9 65 SUPERFAMILY SSF88723 4 58 9.53E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_08990 6f12982118a003b3c666cee260712fa9 189 SUPERFAMILY SSF102198 2 188 1.96E-54 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L14_08990 6f12982118a003b3c666cee260712fa9 189 Pfam PF04199 Putative cyclase 3 134 5.0E-24 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L14_08990 6f12982118a003b3c666cee260712fa9 189 Gene3D G3DSA:3.50.30.50 1 188 1.8E-56 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L14_05180 944282ae17178f2d42679f26a109deec 207 SUPERFAMILY SSF74784 3 182 1.29E-36 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A3L14_05180 944282ae17178f2d42679f26a109deec 207 Gene3D G3DSA:1.20.58.2140 3 201 2.5E-65 T 23-10-2018 A3L14_05180 944282ae17178f2d42679f26a109deec 207 Pfam PF01997 Translin family 21 181 2.2E-10 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 A3L14_10820 ffbe61c25a368b223a5cbab37ad50584 71 SUPERFAMILY SSF46785 12 58 2.92E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_10275 f0736ba3c481ccfcc39b5bcb9c9c6536 151 Gene3D G3DSA:3.30.54.20 73 119 5.9E-59 T 23-10-2018 A3L14_10275 f0736ba3c481ccfcc39b5bcb9c9c6536 151 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 103 133 1.6E-4 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L14_10275 f0736ba3c481ccfcc39b5bcb9c9c6536 151 SUPERFAMILY SSF55186 5 148 2.22E-40 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L14_10275 f0736ba3c481ccfcc39b5bcb9c9c6536 151 Gene3D G3DSA:3.30.980.10 8 148 5.9E-59 T 23-10-2018 A3L14_11210 41a717c4551a5e3b8dd97a79b2d78f5a 118 Pfam PF07883 Cupin domain 38 104 7.6E-17 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L14_11210 41a717c4551a5e3b8dd97a79b2d78f5a 118 SUPERFAMILY SSF51182 6 106 6.88E-29 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_11210 41a717c4551a5e3b8dd97a79b2d78f5a 118 Gene3D G3DSA:2.60.120.10 4 116 2.1E-34 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_03625 8723152eba03d68412cabe6965a54069 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.449 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L14_03625 8723152eba03d68412cabe6965a54069 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 3.0E-52 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L14_03625 8723152eba03d68412cabe6965a54069 152 SMART SM00739 92 119 4.2E-7 T 23-10-2018 IPR005824 KOW A3L14_03625 8723152eba03d68412cabe6965a54069 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 4.2E-23 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L14_03625 8723152eba03d68412cabe6965a54069 152 Pfam PF00467 KOW motif 95 126 1.3E-8 T 23-10-2018 IPR005824 KOW A3L14_03625 8723152eba03d68412cabe6965a54069 152 Gene3D G3DSA:3.30.70.940 2 87 1.3E-33 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L14_03625 8723152eba03d68412cabe6965a54069 152 Gene3D G3DSA:2.30.30.30 88 152 4.0E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L14_03625 8723152eba03d68412cabe6965a54069 152 SUPERFAMILY SSF50104 55 147 3.05E-17 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L14_03625 8723152eba03d68412cabe6965a54069 152 SMART SM00738 3 87 7.2E-20 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L14_01170 822f31f57838cfa82e9f57bf02965954 178 Gene3D G3DSA:3.40.50.300 3 178 3.9E-61 T 23-10-2018 A3L14_01170 822f31f57838cfa82e9f57bf02965954 178 SUPERFAMILY SSF52540 4 174 6.39E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_01170 822f31f57838cfa82e9f57bf02965954 178 Pfam PF01583 Adenylylsulphate kinase 6 157 8.2E-61 T 23-10-2018 A3L14_01170 822f31f57838cfa82e9f57bf02965954 178 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 170 9.1E-69 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L14_01170 822f31f57838cfa82e9f57bf02965954 178 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 5 175 37.462 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L14_11490 fffc2e84e0847141f70a22c13488fdff 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 154 195 4.3E-7 T 23-10-2018 A3L14_11490 fffc2e84e0847141f70a22c13488fdff 305 SUPERFAMILY SSF46785 139 198 5.65E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_11490 fffc2e84e0847141f70a22c13488fdff 305 Gene3D G3DSA:1.10.10.10 154 199 3.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_10295 68df5627ff78592f57a068077ac951f7 131 Gene3D G3DSA:3.30.460.10 1 101 3.9E-15 T 23-10-2018 A3L14_10295 68df5627ff78592f57a068077ac951f7 131 SUPERFAMILY SSF81301 5 104 4.78E-16 T 23-10-2018 A3L14_10295 68df5627ff78592f57a068077ac951f7 131 Pfam PF01909 Nucleotidyltransferase domain 10 109 9.2E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_09375 d73955e990fd1e6e88e9b5abacf1768e 115 SUPERFAMILY SSF69695 1 108 1.83E-23 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_09375 d73955e990fd1e6e88e9b5abacf1768e 115 Gene3D G3DSA:3.30.56.30 1 106 1.0E-30 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_09375 d73955e990fd1e6e88e9b5abacf1768e 115 Pfam PF01922 SRP19 protein 5 91 1.5E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L14_09375 d73955e990fd1e6e88e9b5abacf1768e 115 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 94 21.474 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type A3L14_09175 5e07b373e6036f7b501f282ba99b6244 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 4.1E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L14_09175 5e07b373e6036f7b501f282ba99b6244 67 SMART SM00803 12 66 0.002 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L14_09175 5e07b373e6036f7b501f282ba99b6244 67 Gene3D G3DSA:1.10.20.10 1 67 6.0E-23 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_09175 5e07b373e6036f7b501f282ba99b6244 67 SUPERFAMILY SSF47113 3 66 6.79E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_10540 8b1ecde9f867e7bae0ac1aebc12265de 124 Pfam PF01850 PIN domain 3 118 1.2E-17 T 23-10-2018 IPR002716 PIN domain A3L14_10540 8b1ecde9f867e7bae0ac1aebc12265de 124 SUPERFAMILY SSF88723 2 122 3.36E-22 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_10540 8b1ecde9f867e7bae0ac1aebc12265de 124 Gene3D G3DSA:3.40.50.1010 2 123 2.8E-15 T 23-10-2018 A3L14_10540 8b1ecde9f867e7bae0ac1aebc12265de 124 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 124 10.345 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 101 134 1.3E-8 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 93 1.6E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 2.8E-13 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 SUPERFAMILY SSF53137 2 195 9.16E-63 T 23-10-2018 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 Gene3D G3DSA:3.30.420.100 1 198 3.5E-71 T 23-10-2018 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.825 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02575 94dc9b55e2ebdb9ed17703d01f13df9a 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_01120 ca76120687101f3063dd02de6dee83bd 321 SUPERFAMILY SSF53448 1 276 1.31E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01120 ca76120687101f3063dd02de6dee83bd 321 Pfam PF00535 Glycosyl transferase family 2 7 125 2.2E-20 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_01120 ca76120687101f3063dd02de6dee83bd 321 Gene3D G3DSA:3.90.550.10 1 227 8.4E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 3.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 Gene3D G3DSA:1.10.10.60 1 65 1.4E-32 T 23-10-2018 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 SUPERFAMILY SSF46924 2 63 2.09E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.786 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 2 58 2.7E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_02695 dfea653c364ba54c0caae0bdcae7485e 65 PIRSF PIRSF005653 1 65 1.7E-31 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L14_06980 d7d98dade8feb44dffccaeea87823bb7 373 Pfam PF02687 FtsX-like permease family 278 367 2.9E-10 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A3L14_06980 d7d98dade8feb44dffccaeea87823bb7 373 Pfam PF12704 MacB-like periplasmic core domain 15 218 1.7E-9 T 23-10-2018 IPR025857 MacB-like periplasmic core domain A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 361 6.6E-106 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 SUPERFAMILY SSF103486 35 361 6.8E-77 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 Gene3D G3DSA:1.20.1690.10 112 209 3.6E-59 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 Gene3D G3DSA:1.10.132.50 35 354 3.6E-59 T 23-10-2018 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 3.5E-65 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 24.994 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L14_00715 0a60cb27256718e043909a54e24b5a42 366 Gene3D G3DSA:1.20.1690.10 220 323 3.6E-59 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 Gene3D G3DSA:3.40.630.10 6 336 1.1E-135 T 23-10-2018 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 Gene3D G3DSA:2.40.30.40 68 161 1.1E-135 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 SUPERFAMILY SSF53187 5 345 7.37E-70 T 23-10-2018 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 1.5E-111 T 23-10-2018 IPR008007 Peptidase M42 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 SUPERFAMILY SSF101821 68 177 1.04E-29 T 23-10-2018 A3L14_08260 413135c58850550ab98d5c2c9011e256 348 PIRSF PIRSF001123 1 348 8.5E-122 T 23-10-2018 IPR008007 Peptidase M42 A3L14_06780 ee26d3f90a22506926161159111cd350 399 Pfam PF07690 Major Facilitator Superfamily 14 348 1.2E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_06780 ee26d3f90a22506926161159111cd350 399 Gene3D G3DSA:1.20.1250.20 5 383 1.5E-27 T 23-10-2018 A3L14_06780 ee26d3f90a22506926161159111cd350 399 SUPERFAMILY SSF103473 15 380 6.54E-29 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_02945 5b01e0252c2dd48eea8f87218ea6d00a 121 Gene3D G3DSA:3.40.50.1010 2 119 7.0E-9 T 23-10-2018 A3L14_02945 5b01e0252c2dd48eea8f87218ea6d00a 121 Pfam PF01850 PIN domain 2 111 3.3E-13 T 23-10-2018 IPR002716 PIN domain A3L14_02945 5b01e0252c2dd48eea8f87218ea6d00a 121 SUPERFAMILY SSF88723 1 116 1.07E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_06175 4c6edd67698d9ff440a19e3ad5ececfc 150 SUPERFAMILY SSF88723 4 147 5.05E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_06175 4c6edd67698d9ff440a19e3ad5ececfc 150 Pfam PF01850 PIN domain 4 143 2.1E-19 T 23-10-2018 IPR002716 PIN domain A3L14_06175 4c6edd67698d9ff440a19e3ad5ececfc 150 Gene3D G3DSA:3.40.50.1010 3 149 9.5E-10 T 23-10-2018 A3L14_11165 d242bbf849d73552e0fec9e1512a2eb8 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 3.5E-93 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L14_11165 d242bbf849d73552e0fec9e1512a2eb8 311 ProSitePatterns PS00869 Renal dipeptidase active site. 99 121 - T 23-10-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L14_11165 d242bbf849d73552e0fec9e1512a2eb8 311 SUPERFAMILY SSF51556 1 310 5.01E-77 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L14_11165 d242bbf849d73552e0fec9e1512a2eb8 311 Gene3D G3DSA:3.20.20.140 1 310 1.5E-94 T 23-10-2018 A3L14_09545 ea637763c95e56225f65dd47f26cb080 112 Gene3D G3DSA:3.40.50.1010 4 109 3.6E-5 T 23-10-2018 A3L14_09545 ea637763c95e56225f65dd47f26cb080 112 SUPERFAMILY SSF88723 45 111 6.17E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_09545 ea637763c95e56225f65dd47f26cb080 112 Pfam PF01850 PIN domain 5 104 2.3E-11 T 23-10-2018 IPR002716 PIN domain A3L14_09705 f3214d8adc085426f4a0f8b5125255a4 435 Pfam PF07282 Putative transposase DNA-binding domain 318 387 2.7E-20 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_09705 f3214d8adc085426f4a0f8b5125255a4 435 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 268 345 2.2E-9 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_09705 f3214d8adc085426f4a0f8b5125255a4 435 Pfam PF01385 Probable transposase 173 298 4.9E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_01020 861d158bc01a11f651e041d0e686377d 578 SUPERFAMILY SSF88713 2 244 5.23E-15 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 Gene3D G3DSA:3.90.550.10 2 220 1.8E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 Gene3D G3DSA:1.20.120.1760 230 423 4.6E-58 T 23-10-2018 A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 Pfam PF12804 MobA-like NTP transferase domain 6 116 1.1E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 317 2.3E-11 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L14_09240 9e79d3f9a33f89a66e72ba69ca579163 432 SUPERFAMILY SSF53448 2 221 4.38E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_11170 569611cb444acfde429bccd0242361db 282 SUPERFAMILY SSF53335 81 261 3.89E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_11170 569611cb444acfde429bccd0242361db 282 Pfam PF13649 Methyltransferase domain 129 230 8.4E-11 T 23-10-2018 A3L14_11170 569611cb444acfde429bccd0242361db 282 Gene3D G3DSA:3.40.50.150 97 280 8.0E-27 T 23-10-2018 A3L14_04890 59b856a798f5980ca74522523ed6d2c1 166 PIRSF PIRSF004897 1 166 7.4E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L14_04890 59b856a798f5980ca74522523ed6d2c1 166 SUPERFAMILY SSF55021 106 164 4.3E-8 T 23-10-2018 A3L14_09440 85d5d17c62520fe3fd909d1f5682937d 133 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 120 1.4E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L14_06230 15e6e2440efab7aa11a6f7f0957cda0c 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 30.33 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L14_06230 15e6e2440efab7aa11a6f7f0957cda0c 290 Pfam PF01435 Peptidase family M48 67 282 7.5E-37 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L14_06230 15e6e2440efab7aa11a6f7f0957cda0c 290 Gene3D G3DSA:3.30.2010.10 61 151 7.5E-33 T 23-10-2018 A3L14_07930 64a39ea2c76cf4ef0fe23df1f5abce12 106 SUPERFAMILY SSF46785 15 104 3.41E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_07930 64a39ea2c76cf4ef0fe23df1f5abce12 106 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 7 94 3.1E-33 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 A3L14_09980 ce10dd35d1d5409a78eaefdeb2f6fed5 121 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 6.0E-26 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A3L14_10850 282de68b73b5c2b534b9615b116292e9 552 Pfam PF03553 Na+/H+ antiporter family 156 507 1.6E-66 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A3L14_04475 481da1207d3a0246f8ad6b7f9d171d08 439 Pfam PF13173 AAA domain 45 169 1.3E-20 T 23-10-2018 A3L14_04475 481da1207d3a0246f8ad6b7f9d171d08 439 Pfam PF13635 Domain of unknown function (DUF4143) 252 399 2.9E-9 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L14_04475 481da1207d3a0246f8ad6b7f9d171d08 439 SUPERFAMILY SSF52540 37 220 8.87E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_00195 6f09de88e5def242641cce18b55134df 185 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 4.2E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00195 6f09de88e5def242641cce18b55134df 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 7.3E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00195 6f09de88e5def242641cce18b55134df 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 7.3E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00195 6f09de88e5def242641cce18b55134df 185 SMART SM00418 11 87 1.8E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_00195 6f09de88e5def242641cce18b55134df 185 Gene3D G3DSA:1.10.10.10 1 85 1.2E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_00195 6f09de88e5def242641cce18b55134df 185 SUPERFAMILY SSF46785 5 130 9.39E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_05100 e1881e377b49b6589034b9efd8db04cc 429 Gene3D G3DSA:1.10.645.10 6 425 6.6E-103 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_05100 e1881e377b49b6589034b9efd8db04cc 429 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 416 425 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L14_05100 e1881e377b49b6589034b9efd8db04cc 429 SUPERFAMILY SSF56762 8 425 6.15E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_05100 e1881e377b49b6589034b9efd8db04cc 429 Pfam PF00374 Nickel-dependent hydrogenase 307 425 2.1E-10 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_05100 e1881e377b49b6589034b9efd8db04cc 429 Pfam PF00374 Nickel-dependent hydrogenase 43 128 3.3E-11 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L14_03970 4f84cb2a14b5be641c89610ad2ea18a1 371 Pfam PF05763 Protein of unknown function (DUF835) 231 368 4.3E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_08340 3af70483182e51152d478b62f17fe440 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 14 268 1.1E-72 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L14_08340 3af70483182e51152d478b62f17fe440 346 PIRSF PIRSF000112 1 343 9.4E-66 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L14_08340 3af70483182e51152d478b62f17fe440 346 Gene3D G3DSA:3.40.50.1970 1 155 5.2E-35 T 23-10-2018 A3L14_08340 3af70483182e51152d478b62f17fe440 346 SUPERFAMILY SSF56796 1 339 6.15E-72 T 23-10-2018 A3L14_08340 3af70483182e51152d478b62f17fe440 346 Gene3D G3DSA:1.20.1090.10 156 345 6.4E-66 T 23-10-2018 A3L14_08340 3af70483182e51152d478b62f17fe440 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 346 46.282 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L14_04190 80d7e2782d43ea82775fa0a3d73156da 289 Pfam PF12679 ABC-2 family transporter protein 7 288 2.2E-41 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L14_10880 a3afbf515da699fb24b542b6986cda45 115 Pfam PF03788 LrgA family 15 106 1.6E-28 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 A3L14_00040 ea0951488ec48db785174990dbf2a1a5 345 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 2.9E-59 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L14_00040 ea0951488ec48db785174990dbf2a1a5 345 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 335 1.2E-61 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L14_04880 f2800ed7347a09d93e0b7ad805cbadab 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 2.5E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L14_06285 5ff0759c68d58e9bf2a882fba7cf769a 154 Gene3D G3DSA:2.30.130.90 55 149 3.0E-10 T 23-10-2018 A3L14_06285 5ff0759c68d58e9bf2a882fba7cf769a 154 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 97 145 7.9E-15 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 2 250 44.359 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 4 249 2.1E-93 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 SUPERFAMILY SSF51905 3 242 1.02E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 PRINTS PR00419 Adrenodoxin reductase family signature 26 48 1.4E-7 T 23-10-2018 A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 PRINTS PR00419 Adrenodoxin reductase family signature 49 62 1.4E-7 T 23-10-2018 A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 Gene3D G3DSA:3.50.50.60 1 252 1.9E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_05500 4307b8bfcb0c22915b17bb0154213cfa 252 Pfam PF01946 Thi4 family 8 231 2.9E-79 T 23-10-2018 A3L14_01795 3f79ede85d212830a350bbc2de274e84 138 SMART SM00670 7 113 2.6E-9 T 23-10-2018 IPR002716 PIN domain A3L14_01795 3f79ede85d212830a350bbc2de274e84 138 Gene3D G3DSA:3.40.50.1010 7 136 5.4E-30 T 23-10-2018 A3L14_01795 3f79ede85d212830a350bbc2de274e84 138 SUPERFAMILY SSF88723 7 130 1.77E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_01795 3f79ede85d212830a350bbc2de274e84 138 Pfam PF04900 Fcf1 33 130 2.8E-7 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A3L14_08710 a2e8a273ab862ab115fd55a65761048b 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.1 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_08710 a2e8a273ab862ab115fd55a65761048b 51 Pfam PF00832 Ribosomal L39 protein 9 50 3.1E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_08710 a2e8a273ab862ab115fd55a65761048b 51 Gene3D G3DSA:1.10.1620.10 2 51 9.7E-19 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L14_08710 a2e8a273ab862ab115fd55a65761048b 51 SUPERFAMILY SSF48662 4 50 1.83E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L14_07140 ed42e397846ab342cd8eda9c0090b523 285 Pfam PF03239 Iron permease FTR1 family 3 263 1.4E-64 T 23-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 A3L14_07995 36860832805fc015843bd82bc44c4dd1 195 SUPERFAMILY SSF53448 18 150 2.85E-8 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_07995 36860832805fc015843bd82bc44c4dd1 195 Gene3D G3DSA:3.90.550.10 16 194 2.0E-11 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_08880 b655278331d0aab671f20148620c8beb 155 Pfam PF00583 Acetyltransferase (GNAT) family 16 129 2.8E-14 T 23-10-2018 IPR000182 GNAT domain A3L14_08880 b655278331d0aab671f20148620c8beb 155 Gene3D G3DSA:3.40.630.30 8 152 1.7E-26 T 23-10-2018 A3L14_08880 b655278331d0aab671f20148620c8beb 155 SUPERFAMILY SSF55729 21 152 6.06E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_07370 42b2293ff41bd7138dc34894f2e03552 192 SUPERFAMILY SSF56524 42 182 2.09E-36 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A3L14_07370 42b2293ff41bd7138dc34894f2e03552 192 Pfam PF00174 Oxidoreductase molybdopterin binding domain 42 173 2.2E-23 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A3L14_07370 42b2293ff41bd7138dc34894f2e03552 192 Gene3D G3DSA:3.90.420.10 41 189 3.5E-29 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 Gene3D G3DSA:3.40.1350.10 2 129 8.0E-40 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 PIRSF PIRSF004985 1 126 3.0E-40 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 SUPERFAMILY SSF52980 3 109 1.34E-28 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 37.847 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 6.6E-31 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A3L14_04025 ea9ac5a0baa015e88415d13db87eaf6a 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 126 7.0E-30 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 SUPERFAMILY SSF75445 131 207 7.33E-25 T 23-10-2018 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 Gene3D G3DSA:3.40.50.1360 5 221 3.2E-89 T 23-10-2018 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.235 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 5.4E-65 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 9.4E-82 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 Gene3D G3DSA:3.30.70.260 127 205 3.2E-89 T 23-10-2018 A3L14_03055 7037b97f5a4535842584e26fc31a8e20 227 SUPERFAMILY SSF100950 2 150 2.34E-45 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L14_06765 ea1466790556f2c5b70302fd47d95d46 440 Pfam PF01523 Putative modulator of DNA gyrase 23 303 1.4E-47 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_06765 ea1466790556f2c5b70302fd47d95d46 440 SUPERFAMILY SSF111283 3 436 9.68E-92 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_06765 ea1466790556f2c5b70302fd47d95d46 440 Gene3D G3DSA:3.30.2290.10 3 209 1.3E-14 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_07390 30ed5b1cf8fac51cf7f6a13a6dda7fef 247 Pfam PF12730 ABC-2 family transporter protein 56 173 4.0E-8 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L14_05900 ed97366ae8f96eb960defbc9db358b1c 264 SUPERFAMILY SSF52402 3 184 6.17E-32 T 23-10-2018 A3L14_05900 ed97366ae8f96eb960defbc9db358b1c 264 Gene3D G3DSA:3.40.50.620 19 208 5.8E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_05900 ed97366ae8f96eb960defbc9db358b1c 264 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 3.0E-7 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L14_05900 ed97366ae8f96eb960defbc9db358b1c 264 PIRSF PIRSF036670 1 261 3.0E-120 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A3L14_09100 c78c8699dfeb5b2f35ac12daf928e3c0 428 Gene3D G3DSA:3.40.190.10 26 423 2.3E-52 T 23-10-2018 A3L14_09100 c78c8699dfeb5b2f35ac12daf928e3c0 428 Pfam PF13416 Bacterial extracellular solute-binding protein 53 348 1.3E-41 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L14_09100 c78c8699dfeb5b2f35ac12daf928e3c0 428 SUPERFAMILY SSF53850 21 420 2.55E-58 T 23-10-2018 A3L14_10960 06913bd0364e09add217a9daf40d8d12 417 SUPERFAMILY SSF52540 21 388 1.48E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09225 f642132dd35c79fc7a701ea8b9c51439 981 SUPERFAMILY SSF52540 354 674 1.05E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_10595 c6b109513d80f3299572df695a3cb8c7 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 30 103 4.1E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L14_10595 c6b109513d80f3299572df695a3cb8c7 105 SUPERFAMILY SSF54862 30 102 8.9E-24 T 23-10-2018 A3L14_10595 c6b109513d80f3299572df695a3cb8c7 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_10595 c6b109513d80f3299572df695a3cb8c7 105 Gene3D G3DSA:3.30.70.20 8 105 1.4E-16 T 23-10-2018 A3L14_10595 c6b109513d80f3299572df695a3cb8c7 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 1.8E-12 T 23-10-2018 A3L14_04040 13238a59bff4335a8118131388670291 224 SUPERFAMILY SSF159612 3 218 6.93E-111 T 23-10-2018 A3L14_04040 13238a59bff4335a8118131388670291 224 Gene3D G3DSA:3.90.79.30 100 219 1.8E-61 T 23-10-2018 A3L14_04040 13238a59bff4335a8118131388670291 224 Gene3D G3DSA:3.40.1350.70 1 99 7.9E-49 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A3L14_04040 13238a59bff4335a8118131388670291 224 Pfam PF15517 TBP-interacting protein N-terminus 3 101 5.2E-44 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A3L14_09320 b99bc18cc49d1e56655eda8a34c07ab8 122 Pfam PF09946 Predicted membrane protein (DUF2178) 9 110 1.7E-9 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L14_08885 a1274a52c956fe969c76ee66e1840201 393 SUPERFAMILY SSF103473 23 383 3.92E-29 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_08885 a1274a52c956fe969c76ee66e1840201 393 Gene3D G3DSA:1.20.1250.20 18 383 1.2E-25 T 23-10-2018 A3L14_10035 bbbbc59f0c0c03e733b7d5b9912246ff 304 Pfam PF01895 PhoU domain 138 230 1.7E-14 T 23-10-2018 IPR026022 PhoU domain A3L14_10035 bbbbc59f0c0c03e733b7d5b9912246ff 304 SUPERFAMILY SSF109755 125 301 2.62E-17 T 23-10-2018 A3L14_10035 bbbbc59f0c0c03e733b7d5b9912246ff 304 Gene3D G3DSA:1.20.58.220 134 238 1.3E-11 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L14_10035 bbbbc59f0c0c03e733b7d5b9912246ff 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 3.1E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_10035 bbbbc59f0c0c03e733b7d5b9912246ff 304 SMART SM00966 8 54 4.7E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 2.0E-17 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 2.0E-17 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 2.0E-17 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 2.0E-17 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 Gene3D G3DSA:3.50.50.60 294 481 4.1E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 Gene3D G3DSA:3.50.50.60 154 283 1.4E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 1.8E-205 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 SUPERFAMILY SSF51971 340 473 6.47E-16 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 8.5E-40 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 Gene3D G3DSA:1.10.1060.10 4 151 3.0E-38 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 SUPERFAMILY SSF51971 157 408 1.06E-71 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 1.2E-25 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 1.2E-25 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 1.2E-25 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 1.2E-25 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 1.2E-25 T 23-10-2018 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 6.2E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L14_09400 c1b18268d3e2cb4f70f34797ca740378 481 SUPERFAMILY SSF46548 5 168 1.05E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L14_00250 5323a9d9cabf117f3411eb99e9e87ba9 225 SUPERFAMILY SSF56529 12 218 1.7E-81 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L14_00250 5323a9d9cabf117f3411eb99e9e87ba9 225 Gene3D G3DSA:3.90.850.10 2 221 3.0E-91 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L14_00250 5323a9d9cabf117f3411eb99e9e87ba9 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 4.6E-71 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A3L14_02250 8405264daaf55d7b0bedef14fdf317c1 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L14_02250 8405264daaf55d7b0bedef14fdf317c1 154 SUPERFAMILY SSF51230 77 153 5.23E-27 T 23-10-2018 IPR011053 Single hybrid motif A3L14_02250 8405264daaf55d7b0bedef14fdf317c1 154 Gene3D G3DSA:2.40.50.100 80 154 1.4E-30 T 23-10-2018 A3L14_02250 8405264daaf55d7b0bedef14fdf317c1 154 Pfam PF00364 Biotin-requiring enzyme 88 153 2.8E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L14_01750 79256714ec4ec4de983cf8573fbdc042 212 PIRSF PIRSF019202 1 212 2.6E-45 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L14_01750 79256714ec4ec4de983cf8573fbdc042 212 Pfam PF04254 Protein of unknown function (DUF432) 51 165 2.7E-27 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L14_07415 a233263791fe32ad307dbc263b5a565f 296 SUPERFAMILY SSF55681 11 255 1.37E-31 T 23-10-2018 A3L14_07415 a233263791fe32ad307dbc263b5a565f 296 Gene3D G3DSA:3.30.930.10 10 254 1.1E-35 T 23-10-2018 A3L14_07415 a233263791fe32ad307dbc263b5a565f 296 Pfam PF13393 Histidyl-tRNA synthetase 191 256 1.9E-8 T 23-10-2018 A3L14_07415 a233263791fe32ad307dbc263b5a565f 296 Pfam PF13393 Histidyl-tRNA synthetase 4 173 8.7E-17 T 23-10-2018 A3L14_05740 d4385775a74f455d9d100c5bb6058c7a 417 Pfam PF07690 Major Facilitator Superfamily 23 357 2.7E-30 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_05740 d4385775a74f455d9d100c5bb6058c7a 417 SUPERFAMILY SSF103473 24 403 2.22E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_05740 d4385775a74f455d9d100c5bb6058c7a 417 Gene3D G3DSA:1.20.1250.20 8 400 2.6E-37 T 23-10-2018 A3L14_05060 33af34192b491e607b83f414f5553502 123 Gene3D G3DSA:3.40.140.10 2 123 4.2E-28 T 23-10-2018 A3L14_05060 33af34192b491e607b83f414f5553502 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 101 4.2E-11 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L14_05060 33af34192b491e607b83f414f5553502 123 SUPERFAMILY SSF102712 3 121 9.94E-29 T 23-10-2018 A3L14_00745 43c82dcb5975ac2c5a9d47ac446bc61b 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 328 2.4E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L14_00745 43c82dcb5975ac2c5a9d47ac446bc61b 338 Gene3D G3DSA:1.10.3720.10 109 332 5.4E-6 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_00745 43c82dcb5975ac2c5a9d47ac446bc61b 338 SUPERFAMILY SSF161098 93 321 1.22E-5 T 23-10-2018 IPR035906 MetI-like superfamily A3L14_10545 a970802b34a0eef8692da1c99824aac2 75 SUPERFAMILY SSF89447 2 51 3.79E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L14_10545 a970802b34a0eef8692da1c99824aac2 75 SMART SM00966 1 42 8.1E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_10545 a970802b34a0eef8692da1c99824aac2 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 39 1.9E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L14_09455 eaf5548e4959aa5b089adff274d1998f 135 Gene3D G3DSA:3.30.70.260 47 131 1.6E-9 T 23-10-2018 A3L14_09455 eaf5548e4959aa5b089adff274d1998f 135 Pfam PF01842 ACT domain 59 117 1.2E-10 T 23-10-2018 IPR002912 ACT domain A3L14_09455 eaf5548e4959aa5b089adff274d1998f 135 SUPERFAMILY SSF55021 60 130 4.58E-11 T 23-10-2018 A3L14_01190 cee4c84f82fef39c641f080abbd75c42 311 SUPERFAMILY SSF64182 3 310 2.35E-28 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L14_04760 792697b2a20cb3b91d36cafbfdaf2289 128 SUPERFAMILY SSF47413 14 52 1.01E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L14_04760 792697b2a20cb3b91d36cafbfdaf2289 128 Pfam PF01022 Bacterial regulatory protein, arsR family 17 51 4.7E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L14_04760 792697b2a20cb3b91d36cafbfdaf2289 128 Gene3D G3DSA:1.10.260.40 16 60 2.7E-6 T 23-10-2018 A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 PRINTS PR01035 Tetracycline resistance protein signature 298 318 4.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 PRINTS PR01035 Tetracycline resistance protein signature 135 157 4.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 PRINTS PR01035 Tetracycline resistance protein signature 17 33 4.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 SUPERFAMILY SSF103473 6 379 5.49E-56 T 23-10-2018 IPR036259 MFS transporter superfamily A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 Pfam PF07690 Major Facilitator Superfamily 13 294 2.9E-35 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L14_10025 94659ab243302bcc8dc5111e1ca97289 390 Gene3D G3DSA:1.20.1250.20 3 381 1.3E-48 T 23-10-2018 A3L14_04615 56c8971df813253ec9d889547d8cfc39 261 Pfam PF01261 Xylose isomerase-like TIM barrel 49 212 6.5E-16 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L14_04615 56c8971df813253ec9d889547d8cfc39 261 SUPERFAMILY SSF51658 1 239 3.27E-30 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L14_04615 56c8971df813253ec9d889547d8cfc39 261 Gene3D G3DSA:3.20.20.150 12 258 4.4E-36 T 23-10-2018 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 Gene3D G3DSA:3.30.310.10 16 97 3.2E-33 T 23-10-2018 IPR012295 TBP domain superfamily A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.746 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.2E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 1.3E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 8.3E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 SUPERFAMILY SSF55945 5 95 1.88E-29 T 23-10-2018 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 SUPERFAMILY SSF55945 96 182 2.2E-30 T 23-10-2018 A3L14_09535 d32a1f2c4df1ba100170dd4057a54387 190 Gene3D G3DSA:3.30.310.10 98 182 3.7E-35 T 23-10-2018 IPR012295 TBP domain superfamily A3L14_05415 f038c964ae013e2ec9fcc635ae67bfa2 596 Pfam PF16286 Domain of unknown function (DUF4932) 29 180 4.0E-9 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A3L14_05415 f038c964ae013e2ec9fcc635ae67bfa2 596 Pfam PF05124 S-layer like family, C-terminal region 454 564 2.1E-8 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L14_03655 2bf3e5747805e0253c0e7a1561dd4902 151 Pfam PF08905 Domain of unknown function (DUF1850) 44 89 7.5E-7 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 A3L14_05105 63b000052a5ea740c2a6a0fee7ae6d36 264 SUPERFAMILY SSF56770 5 211 2.75E-43 T 23-10-2018 A3L14_05105 63b000052a5ea740c2a6a0fee7ae6d36 264 Gene3D G3DSA:3.40.50.700 4 164 9.7E-41 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L14_05105 63b000052a5ea740c2a6a0fee7ae6d36 264 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 150 4.4E-25 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_10265 e29e3d6922c716e7e8509c59b87d133e 86 Gene3D G3DSA:1.10.1220.10 2 46 1.6E-6 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L14_10265 e29e3d6922c716e7e8509c59b87d133e 86 SUPERFAMILY SSF47598 3 45 6.45E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_05310 2e78a6918b2634068d0e3166929e7de2 436 Pfam PF01385 Probable transposase 182 299 1.3E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_05310 2e78a6918b2634068d0e3166929e7de2 436 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 346 7.8E-10 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_05310 2e78a6918b2634068d0e3166929e7de2 436 Pfam PF07282 Putative transposase DNA-binding domain 319 388 4.7E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_04060 8714dc5d5e7bedbaf332c5f0fa101980 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 196 4.0E-51 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A3L14_03660 5391b46027957e2e9ef7030fcdb74879 767 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 44 750 1.0E-165 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ A3L14_03660 5391b46027957e2e9ef7030fcdb74879 767 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 463 687 1.6E-26 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A3L14_03660 5391b46027957e2e9ef7030fcdb74879 767 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 142 449 4.1E-58 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A3L14_07605 0abb750761f10c4009983a9c29e76136 152 SUPERFAMILY SSF53146 1 111 5.23E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_07605 0abb750761f10c4009983a9c29e76136 152 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 3.3E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L14_07605 0abb750761f10c4009983a9c29e76136 152 Gene3D G3DSA:3.30.420.130 1 114 1.0E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L14_03830 02f639e02cebae00f3012d4044b75ebd 241 SUPERFAMILY SSF52768 56 223 1.31E-24 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L14_03830 02f639e02cebae00f3012d4044b75ebd 241 PIRSF PIRSF036979 27 231 1.0E-14 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L14_03830 02f639e02cebae00f3012d4044b75ebd 241 Gene3D G3DSA:3.40.800.10 26 240 6.5E-18 T 23-10-2018 A3L14_03830 02f639e02cebae00f3012d4044b75ebd 241 Pfam PF00491 Arginase family 54 224 6.4E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L14_11495 06089305833b2b9be072a938d18ec208 310 Pfam PF13186 Iron-sulfur cluster-binding domain 225 281 3.3E-5 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L14_11495 06089305833b2b9be072a938d18ec208 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 222 301 6.5E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L14_11495 06089305833b2b9be072a938d18ec208 310 Gene3D G3DSA:3.20.20.70 191 309 2.3E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_11495 06089305833b2b9be072a938d18ec208 310 SUPERFAMILY SSF102114 214 286 1.45E-9 T 23-10-2018 A3L14_05975 629f642911f9b2c3a06ad96b3a1242d1 441 Pfam PF01523 Putative modulator of DNA gyrase 15 304 3.3E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_05975 629f642911f9b2c3a06ad96b3a1242d1 441 Gene3D G3DSA:3.30.2290.10 9 207 6.2E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_05975 629f642911f9b2c3a06ad96b3a1242d1 441 SUPERFAMILY SSF111283 2 439 8.63E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_10895 c3016348ae9f7ec4d7327a7804c5aa41 284 Pfam PF16795 Archaeal phage integrase 115 274 1.3E-55 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal A3L14_10895 c3016348ae9f7ec4d7327a7804c5aa41 284 SUPERFAMILY SSF56349 25 263 4.12E-14 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L14_10895 c3016348ae9f7ec4d7327a7804c5aa41 284 Gene3D G3DSA:1.10.443.10 112 279 2.7E-46 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L14_01060 a2e105e49fb108fc31d5933b1524de04 144 Gene3D G3DSA:1.20.1260.10 1 144 2.0E-12 T 23-10-2018 IPR012347 Ferritin-like A3L14_01060 a2e105e49fb108fc31d5933b1524de04 144 Pfam PF02915 Rubrerythrin 30 139 1.5E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L14_01060 a2e105e49fb108fc31d5933b1524de04 144 SUPERFAMILY SSF47240 4 142 1.59E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_00475 d17ef008110bed69d30688785a33fa11 153 Gene3D G3DSA:3.40.50.300 2 153 4.8E-40 T 23-10-2018 A3L14_00475 d17ef008110bed69d30688785a33fa11 153 Pfam PF00685 Sulfotransferase domain 36 147 1.6E-10 T 23-10-2018 IPR000863 Sulfotransferase domain GO:0008146 A3L14_00475 d17ef008110bed69d30688785a33fa11 153 SUPERFAMILY SSF52540 4 148 2.85E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_02085 7713556b35e491eba28df02391b75b75 344 Gene3D G3DSA:3.40.190.10 41 277 2.2E-74 T 23-10-2018 A3L14_02085 7713556b35e491eba28df02391b75b75 344 Gene3D G3DSA:3.40.190.10 117 240 2.2E-74 T 23-10-2018 A3L14_02085 7713556b35e491eba28df02391b75b75 344 Pfam PF12849 PBP superfamily domain 32 271 8.7E-23 T 23-10-2018 IPR024370 PBP domain A3L14_02085 7713556b35e491eba28df02391b75b75 344 SUPERFAMILY SSF53850 39 280 2.17E-23 T 23-10-2018 A3L14_04935 b91345077bce67562c1e37b74361cc33 92 SUPERFAMILY SSF82649 4 86 1.05E-10 T 23-10-2018 A3L14_04935 b91345077bce67562c1e37b74361cc33 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 63 4.1E-8 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A3L14_04935 b91345077bce67562c1e37b74361cc33 92 Gene3D G3DSA:3.30.390.50 1 88 5.0E-27 T 23-10-2018 A3L14_06655 dbe2fb7df57759a500cc4283c9c5212a 93 Pfam PF01910 Thiamine-binding protein 4 92 5.9E-30 T 23-10-2018 IPR002767 Thiamine-binding protein A3L14_06655 dbe2fb7df57759a500cc4283c9c5212a 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 92 1.3E-26 T 23-10-2018 IPR002767 Thiamine-binding protein A3L14_06655 dbe2fb7df57759a500cc4283c9c5212a 93 Gene3D G3DSA:3.30.70.930 1 93 1.4E-32 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L14_06655 dbe2fb7df57759a500cc4283c9c5212a 93 SUPERFAMILY SSF89957 1 92 1.31E-29 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 80 3.7E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 SUPERFAMILY SSF69786 2 93 8.11E-30 T 23-10-2018 IPR036591 YggU-like superfamily A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 94 21.417 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 89 3.4E-30 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 Gene3D G3DSA:3.30.1200.10 1 94 2.6E-34 T 23-10-2018 IPR036591 YggU-like superfamily A3L14_05785 f65a4301876f3fa05e4c37ddb865fdce 94 SMART SM01152 7 82 3.9E-34 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L14_01875 249ca37eabcc4f0149a1935db5372e3e 125 SUPERFAMILY SSF50249 24 88 8.0E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L14_00880 b7037f38b7a321659707233ecd903015 375 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 365 9.8E-35 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L14_08875 34bff43e12bfe5be3a217e275f8fcd20 269 SUPERFAMILY SSF55729 1 132 4.15E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_08875 34bff43e12bfe5be3a217e275f8fcd20 269 Pfam PF00583 Acetyltransferase (GNAT) family 27 125 5.8E-14 T 23-10-2018 IPR000182 GNAT domain A3L14_08875 34bff43e12bfe5be3a217e275f8fcd20 269 Gene3D G3DSA:3.40.630.30 3 187 1.0E-29 T 23-10-2018 A3L14_00735 11afd577d967916b49ca11930a9a7807 217 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 3.6E-72 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00735 11afd577d967916b49ca11930a9a7807 217 Pfam PF01813 ATP synthase subunit D 13 206 9.4E-62 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_00735 11afd577d967916b49ca11930a9a7807 217 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.393 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L14_07920 13159010e566ac65ded64eeace22cba0 217 Pfam PF01917 Archaebacterial flagellin 9 195 8.3E-46 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L14_07920 13159010e566ac65ded64eeace22cba0 217 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 7 30 1.7E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A3L14_09885 79d5e459db3c97f79c4f69fcbab7c286 589 SUPERFAMILY SSF48239 353 480 2.57E-11 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_09885 79d5e459db3c97f79c4f69fcbab7c286 589 Gene3D G3DSA:1.50.10.20 17 142 2.9E-13 T 23-10-2018 A3L14_09885 79d5e459db3c97f79c4f69fcbab7c286 589 Gene3D G3DSA:1.50.10.20 328 522 1.8E-6 T 23-10-2018 A3L14_09885 79d5e459db3c97f79c4f69fcbab7c286 589 SUPERFAMILY SSF48239 17 231 1.39E-19 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L14_06710 63b0f83c698e7c52d1e8a83c98b7ffe8 238 SUPERFAMILY SSF55486 173 220 1.86E-8 T 23-10-2018 A3L14_06710 63b0f83c698e7c52d1e8a83c98b7ffe8 238 Gene3D G3DSA:3.40.390.10 74 227 5.0E-18 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L14_06710 63b0f83c698e7c52d1e8a83c98b7ffe8 238 Pfam PF07998 Peptidase family M54 1 138 2.7E-19 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L14_06710 63b0f83c698e7c52d1e8a83c98b7ffe8 238 Pfam PF07998 Peptidase family M54 167 223 6.3E-21 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L14_10300 dddc362b19295686d2a3620cd8b6f672 135 SUPERFAMILY SSF81593 4 128 6.67E-43 T 23-10-2018 A3L14_10300 dddc362b19295686d2a3620cd8b6f672 135 SMART SM00748 10 122 1.2E-44 T 23-10-2018 IPR007842 HEPN domain A3L14_10300 dddc362b19295686d2a3620cd8b6f672 135 Gene3D G3DSA:1.20.120.330 1 131 2.0E-38 T 23-10-2018 A3L14_10300 dddc362b19295686d2a3620cd8b6f672 135 Pfam PF05168 HEPN domain 6 127 4.9E-33 T 23-10-2018 IPR007842 HEPN domain A3L14_08170 4622e60c786a9db44c8019ef99f27e12 238 SUPERFAMILY SSF56059 20 236 3.54E-45 T 23-10-2018 A3L14_08170 4622e60c786a9db44c8019ef99f27e12 238 Gene3D G3DSA:3.30.470.20 17 232 1.5E-90 T 23-10-2018 A3L14_08170 4622e60c786a9db44c8019ef99f27e12 238 Pfam PF13549 ATP-grasp domain 12 234 6.0E-80 T 23-10-2018 A3L14_08170 4622e60c786a9db44c8019ef99f27e12 238 Gene3D G3DSA:3.30.1490.20 38 115 1.5E-90 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 Gene3D G3DSA:3.30.70.580 1 103 2.5E-23 T 23-10-2018 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 PIRSF PIRSF001430 1 243 2.0E-76 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 SUPERFAMILY SSF55120 1 235 1.04E-64 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 30.795 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 1.5E-22 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 222 8.7E-52 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L14_04215 b92dfec596b3c108e5d66f20f92f1124 267 Gene3D G3DSA:3.30.70.660 104 226 1.0E-26 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A3L14_08335 279b2ebb36c8073d533c4a73964e6b3c 270 Pfam PF01889 Membrane protein of unknown function DUF63 4 269 3.9E-85 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L14_09460 6c771c347d4eb75ea532ece351539767 382 Pfam PF00999 Sodium/hydrogen exchanger family 8 361 3.1E-27 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L14_09460 6c771c347d4eb75ea532ece351539767 382 Gene3D G3DSA:1.20.1530.20 2 380 5.0E-43 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L14_07900 7c585318eb575cbe97e4eb1a56ff3ecf 149 Pfam PF01917 Archaebacterial flagellin 2 145 1.0E-15 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A3L14_10620 65c02a8a3d458a03c3bbec43ac40be71 244 PIRSF PIRSF019322 2 244 2.0E-87 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L14_10620 65c02a8a3d458a03c3bbec43ac40be71 244 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 2.0E-72 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L14_06305 869e579c65b4045e90952bb6f2ce262a 86 Pfam PF12651 Ribbon-helix-helix domain 3 41 4.8E-5 T 23-10-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain A3L14_11485 732d8c1b17ac8543c0bfbfb5864c1cc2 162 Gene3D G3DSA:3.40.1520.10 1 162 4.4E-71 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L14_11485 732d8c1b17ac8543c0bfbfb5864c1cc2 162 Pfam PF04008 Adenosine specific kinase 7 160 2.8E-61 T 23-10-2018 IPR007153 Adenosine specific kinase A3L14_11485 732d8c1b17ac8543c0bfbfb5864c1cc2 162 SUPERFAMILY SSF103165 2 160 1.7E-59 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L14_09805 191000f05db238dcc891e14d80c5f7ee 88 SUPERFAMILY SSF47598 4 47 9.45E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_09805 191000f05db238dcc891e14d80c5f7ee 88 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 43 2.2E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L14_09805 191000f05db238dcc891e14d80c5f7ee 88 Gene3D G3DSA:1.10.1220.10 11 47 2.6E-7 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L14_00895 18783e53246829dcfd774afd26175899 247 Pfam PF05971 Protein of unknown function (DUF890) 31 164 4.9E-10 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A3L14_00895 18783e53246829dcfd774afd26175899 247 SUPERFAMILY SSF53335 8 233 3.35E-24 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_00895 18783e53246829dcfd774afd26175899 247 Gene3D G3DSA:3.40.50.150 66 246 2.5E-40 T 23-10-2018 A3L14_04030 d61ffc133bd9c47072183e38ebb82a11 174 Gene3D G3DSA:2.160.10.10 1 172 3.3E-64 T 23-10-2018 A3L14_04030 d61ffc133bd9c47072183e38ebb82a11 174 SUPERFAMILY SSF51161 4 169 1.28E-51 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L14_04030 d61ffc133bd9c47072183e38ebb82a11 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 2.9E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L14_01165 ff291db861e886b489e4a32704c3fc3e 245 Pfam PF01925 Sulfite exporter TauE/SafE 6 239 4.5E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L14_01775 ccd81d37281914f495cb5a285bdc4069 76 SUPERFAMILY SSF141694 16 70 1.36E-10 T 23-10-2018 A3L14_01775 ccd81d37281914f495cb5a285bdc4069 76 Pfam PF01954 Protein of unknown function DUF104 16 69 1.9E-11 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_08040 b9716727f6e445843f8e62fbe33e07b9 390 Pfam PF13173 AAA domain 41 157 1.9E-21 T 23-10-2018 A3L14_08040 b9716727f6e445843f8e62fbe33e07b9 390 SUPERFAMILY SSF52540 23 169 2.64E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_08040 b9716727f6e445843f8e62fbe33e07b9 390 Gene3D G3DSA:1.10.10.10 211 310 1.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_08040 b9716727f6e445843f8e62fbe33e07b9 390 SUPERFAMILY SSF46785 237 290 3.46E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 SUPERFAMILY SSF54189 1 191 8.15E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 Gene3D G3DSA:3.40.1120.10 1 193 2.2E-89 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 Pfam PF00827 Ribosomal L15 2 189 1.3E-88 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 SMART SM01384 2 191 3.1E-133 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L14_02930 ca74efafbe5f48e1caae23d72c531291 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.145 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L14_11235 9121ada2641f728e5865f9b8873f4a19 165 Pfam PF01899 Na+/H+ ion antiporter subunit 7 162 5.1E-46 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_11235 9121ada2641f728e5865f9b8873f4a19 165 PIRSF PIRSF019239 1 164 1.1E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 SUPERFAMILY SSF54862 3 61 7.7E-17 T 23-10-2018 A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 Gene3D G3DSA:3.30.70.20 37 63 3.9E-6 T 23-10-2018 A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 Gene3D G3DSA:3.30.70.20 1 36 8.8E-7 T 23-10-2018 A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 Pfam PF00037 4Fe-4S binding domain 7 29 8.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 Pfam PF00037 4Fe-4S binding domain 38 58 1.5E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_03710 bee949a62b79d7f59cfcfcbcf493aa53 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_00640 9fa1ced8ffc50437d4451350fcc91ebb 250 SUPERFAMILY SSF102705 1 245 2.75E-68 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A3L14_00640 9fa1ced8ffc50437d4451350fcc91ebb 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 2.9E-61 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L14_00640 9fa1ced8ffc50437d4451350fcc91ebb 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 238 1.8E-57 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L14_00640 9fa1ced8ffc50437d4451350fcc91ebb 250 Gene3D G3DSA:3.40.1390.30 6 238 9.6E-78 T 23-10-2018 A3L14_00640 9fa1ced8ffc50437d4451350fcc91ebb 250 Gene3D G3DSA:3.40.1390.30 96 221 9.6E-78 T 23-10-2018 A3L14_07745 e4a123eb2428591b7f6ff1e3c01c932b 81 Hamap MF_01245 UPF0248 protein . 10 79 19.566 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L14_07745 e4a123eb2428591b7f6ff1e3c01c932b 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 2.1E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L14_07130 18c9e739199afa50640573997ccb294c 125 Gene3D G3DSA:3.30.310.70 1 125 3.4E-10 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_07130 18c9e739199afa50640573997ccb294c 125 Pfam PF03625 Domain of unknown function DUF302 49 86 3.5E-5 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L14_07130 18c9e739199afa50640573997ccb294c 125 SUPERFAMILY SSF103247 2 125 2.09E-16 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L14_05715 9b408861fec7ab09a595aa8f1d2d6348 161 Gene3D G3DSA:1.10.10.10 3 124 5.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_05715 9b408861fec7ab09a595aa8f1d2d6348 161 Pfam PF03551 Transcriptional regulator PadR-like family 22 95 1.8E-15 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_05715 9b408861fec7ab09a595aa8f1d2d6348 161 SUPERFAMILY SSF46785 5 101 7.39E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02315 aa67aa418e3dc9d2febe5ece7a53930b 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 13 77 1.1E-22 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 A3L14_05650 90ed958305c8e6e9bcc119f1d0dfc458 242 Pfam PF02195 ParB-like nuclease domain 22 92 1.2E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L14_05650 90ed958305c8e6e9bcc119f1d0dfc458 242 SMART SM00470 19 114 6.8E-14 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L14_05650 90ed958305c8e6e9bcc119f1d0dfc458 242 Gene3D G3DSA:3.90.1530.10 17 238 1.1E-83 T 23-10-2018 A3L14_05650 90ed958305c8e6e9bcc119f1d0dfc458 242 Gene3D G3DSA:3.30.1760.10 98 227 1.1E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A3L14_05650 90ed958305c8e6e9bcc119f1d0dfc458 242 SUPERFAMILY SSF110849 12 241 5.49E-61 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L14_09215 338b0a5c036e2b5c84b85caa46d3f45e 253 SMART SM00382 26 209 8.3E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L14_09215 338b0a5c036e2b5c84b85caa46d3f45e 253 SUPERFAMILY SSF52540 2 222 6.29E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_09215 338b0a5c036e2b5c84b85caa46d3f45e 253 Gene3D G3DSA:3.40.50.300 1 242 1.8E-68 T 23-10-2018 A3L14_09215 338b0a5c036e2b5c84b85caa46d3f45e 253 Pfam PF00005 ABC transporter 17 161 1.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L14_08345 06efecba6483971a2647809902076bb3 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 4.7E-42 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L14_08345 06efecba6483971a2647809902076bb3 144 PIRSF PIRSF006595 1 144 1.8E-49 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L14_08345 06efecba6483971a2647809902076bb3 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 4.0E-66 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L14_08345 06efecba6483971a2647809902076bb3 144 Hamap MF_00498 UPF0179 protein . 2 141 23.619 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L14_08520 58dc71be0a0f1bf06919893a0137bb8f 218 Gene3D G3DSA:3.20.20.140 2 216 3.2E-45 T 23-10-2018 A3L14_08520 58dc71be0a0f1bf06919893a0137bb8f 218 Pfam PF02811 PHP domain 7 81 1.5E-7 T 23-10-2018 IPR004013 PHP domain GO:0003824 A3L14_08520 58dc71be0a0f1bf06919893a0137bb8f 218 SMART SM00481 6 78 3.4E-10 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A3L14_08520 58dc71be0a0f1bf06919893a0137bb8f 218 SUPERFAMILY SSF89550 6 214 7.59E-36 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L14_09895 99f5bc07ecace7c82cd382fc5d885fe9 246 Gene3D G3DSA:3.40.50.620 56 171 3.3E-7 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L14_09895 99f5bc07ecace7c82cd382fc5d885fe9 246 PIRSF PIRSF006601 1 246 1.0E-87 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A3L14_09895 99f5bc07ecace7c82cd382fc5d885fe9 246 SUPERFAMILY SSF52402 50 173 4.19E-13 T 23-10-2018 A3L14_08445 747ad066a5e291420638d417439ed9dc 129 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 3 127 2.6E-67 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A3L14_01765 664e71f4354c140265d8f3fea7fbba93 219 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 53 2.0E-15 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L14_01765 664e71f4354c140265d8f3fea7fbba93 219 Pfam PF04256 Protein of unknown function (DUF434) 2 56 1.4E-24 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L14_00310 b22286690a3e5f5a082129a52c7dad43 164 SUPERFAMILY SSF54534 2 150 6.87E-50 T 23-10-2018 A3L14_00310 b22286690a3e5f5a082129a52c7dad43 164 Gene3D G3DSA:3.10.50.80 2 158 1.7E-56 T 23-10-2018 A3L14_00310 b22286690a3e5f5a082129a52c7dad43 164 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 2.6E-23 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L14_00660 306e9132024194526c94257c373c5273 171 Pfam PF03692 Putative zinc- or iron-chelating domain 16 108 9.3E-15 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L14_03840 2bf328e8d46bd0736e7b15c558faaec5 251 SUPERFAMILY SSF55307 159 247 8.7E-11 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L14_03840 2bf328e8d46bd0736e7b15c558faaec5 251 Gene3D G3DSA:3.40.50.1440 114 249 4.5E-8 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 1.3E-8 T 23-10-2018 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 1.3E-8 T 23-10-2018 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.3E-8 T 23-10-2018 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 1.3E-8 T 23-10-2018 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 1.3E-8 T 23-10-2018 A3L14_11340 f30a6330e5088081ed152f6162236df2 517 Pfam PF00361 Proton-conducting membrane transporter 138 441 3.5E-52 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04820 b734cbc0dd1aa9304876f7304055c9de 200 Pfam PF06195 Protein of unknown function (DUF996) 37 175 2.3E-25 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L14_09835 fd46a767c0ed17183e17e40d35403e6a 169 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L14_09835 fd46a767c0ed17183e17e40d35403e6a 169 Pfam PF00037 4Fe-4S binding domain 67 88 1.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L14_09835 fd46a767c0ed17183e17e40d35403e6a 169 SUPERFAMILY SSF54862 11 137 2.46E-19 T 23-10-2018 A3L14_09835 fd46a767c0ed17183e17e40d35403e6a 169 Gene3D G3DSA:3.30.70.20 37 105 1.8E-12 T 23-10-2018 A3L14_03735 6205218cb149a91f66623838383ab60d 221 Gene3D G3DSA:3.90.320.10 6 218 1.9E-18 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L14_09555 570389353aa7c3e16d9c96831750ebeb 168 Gene3D G3DSA:3.40.630.30 2 159 4.5E-50 T 23-10-2018 A3L14_09555 570389353aa7c3e16d9c96831750ebeb 168 SUPERFAMILY SSF55729 7 154 2.03E-29 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_09555 570389353aa7c3e16d9c96831750ebeb 168 Pfam PF00583 Acetyltransferase (GNAT) family 20 141 1.1E-19 T 23-10-2018 IPR000182 GNAT domain A3L14_05525 5b932bac80873b77e517883b30f24bb7 195 Gene3D G3DSA:3.60.20.20 2 194 4.4E-45 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L14_05525 5b932bac80873b77e517883b30f24bb7 195 SUPERFAMILY SSF75569 3 193 6.54E-58 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L14_05525 5b932bac80873b77e517883b30f24bb7 195 Pfam PF07826 IMP cyclohydrolase-like protein 3 185 2.8E-46 T 23-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L14_05525 5b932bac80873b77e517883b30f24bb7 195 PIRSF PIRSF004866 2 195 1.1E-64 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L14_06770 2177c662aeec77749b742c2ca416d025 358 Pfam PF05763 Protein of unknown function (DUF835) 221 353 2.1E-31 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_03370 5380ac711026ed106d6beae336319ecb 113 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 108 1.4E-10 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L14_03370 5380ac711026ed106d6beae336319ecb 113 Gene3D G3DSA:2.30.30.110 15 112 7.7E-11 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L14_03370 5380ac711026ed106d6beae336319ecb 113 SUPERFAMILY SSF50118 4 111 1.87E-13 T 23-10-2018 A3L14_05890 19da80c5347b4c3bbd9a497d7d915e79 105 Gene3D G3DSA:3.30.460.10 1 103 1.9E-19 T 23-10-2018 A3L14_05890 19da80c5347b4c3bbd9a497d7d915e79 105 Pfam PF01909 Nucleotidyltransferase domain 13 89 7.7E-14 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_05890 19da80c5347b4c3bbd9a497d7d915e79 105 SUPERFAMILY SSF81301 5 105 2.02E-15 T 23-10-2018 A3L14_00430 00820d983c23f6ea439aabf12f7d0326 294 Pfam PF00535 Glycosyl transferase family 2 6 142 1.7E-32 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_00430 00820d983c23f6ea439aabf12f7d0326 294 SUPERFAMILY SSF53448 3 217 4.22E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_00430 00820d983c23f6ea439aabf12f7d0326 294 Gene3D G3DSA:3.90.550.10 1 240 1.1E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_04415 a4ab47ced75c203d5e5a82181c094852 453 Gene3D G3DSA:3.40.190.10 53 453 6.8E-85 T 23-10-2018 A3L14_04415 a4ab47ced75c203d5e5a82181c094852 453 SUPERFAMILY SSF53850 54 450 1.32E-77 T 23-10-2018 A3L14_04415 a4ab47ced75c203d5e5a82181c094852 453 Pfam PF01547 Bacterial extracellular solute-binding protein 68 369 3.8E-50 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L14_04870 d526240a6a84f967064a9a27dc933f91 94 Pfam PF13244 Domain of unknown function (DUF4040) 14 79 4.3E-19 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L14_06705 8b566484222723fdc456c5f800fdda69 348 Gene3D G3DSA:3.20.20.70 130 343 5.6E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L14_06705 8b566484222723fdc456c5f800fdda69 348 PIRSF PIRSF004869 56 346 3.0E-70 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L14_06705 8b566484222723fdc456c5f800fdda69 348 SUPERFAMILY SSF102114 137 334 2.09E-19 T 23-10-2018 A3L14_06705 8b566484222723fdc456c5f800fdda69 348 Pfam PF04055 Radical SAM superfamily 135 265 8.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L14_06705 8b566484222723fdc456c5f800fdda69 348 Pfam PF13353 4Fe-4S single cluster domain 133 221 2.3E-9 T 23-10-2018 A3L14_06545 98590224f80007be43e5ff4e14beec77 136 SUPERFAMILY SSF46689 85 125 6.72E-6 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L14_06545 98590224f80007be43e5ff4e14beec77 136 Gene3D G3DSA:1.10.10.60 85 128 8.2E-7 T 23-10-2018 A3L14_04130 b49587425f439d836eddc9657cd445f3 449 Gene3D G3DSA:2.60.40.10 23 123 4.6E-9 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L14_05405 0707e7e2f6db4c6a35c5394ba0897906 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 274 6.5E-31 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L14_09190 f74d537315e7c14a21ec83af6829c36a 103 SUPERFAMILY SSF50447 1 72 8.12E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L14_09190 f74d537315e7c14a21ec83af6829c36a 103 Gene3D G3DSA:2.40.10.230 1 75 2.5E-24 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A3L14_09190 f74d537315e7c14a21ec83af6829c36a 103 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 6.0E-16 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A3L14_09190 f74d537315e7c14a21ec83af6829c36a 103 Pfam PF04410 Gar1/Naf1 RNA binding region 3 74 2.0E-9 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A3L14_04970 07cbd318125b9a46da655abbd6a65dc0 63 Pfam PF04021 Class III signal peptide 3 27 1.1E-5 T 23-10-2018 IPR007166 Class III signal peptide motif A3L14_09580 7acf871636bcba68f18da5e472f8f08c 223 Gene3D G3DSA:3.60.160.10 1 223 1.4E-82 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A3L14_09580 7acf871636bcba68f18da5e472f8f08c 223 Pfam PF01987 Mitochondrial biogenesis AIM24 3 205 5.4E-63 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L14_09580 7acf871636bcba68f18da5e472f8f08c 223 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 221 2.2E-88 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L14_09580 7acf871636bcba68f18da5e472f8f08c 223 SUPERFAMILY SSF51219 1 221 8.63E-74 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 30.786 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 174 8.8E-50 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 PIRSF PIRSF006305 1 184 6.2E-60 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 Pfam PF02545 Maf-like protein 2 175 2.0E-56 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 SUPERFAMILY SSF52972 1 175 3.66E-58 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L14_08525 29e537ce461ef5300e3553798e0d3340 186 Gene3D G3DSA:3.90.950.10 1 180 7.3E-65 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L14_08730 8d300f9d38c3de69da63d908f0364dab 160 Gene3D G3DSA:2.60.40.790 2 159 9.3E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A3L14_08730 8d300f9d38c3de69da63d908f0364dab 160 Pfam PF00011 Hsp20/alpha crystallin family 56 151 9.4E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A3L14_08730 8d300f9d38c3de69da63d908f0364dab 160 SUPERFAMILY SSF49764 25 151 7.72E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A3L14_03900 16f0775ab64917b400c9daca11b6a000 277 SUPERFAMILY SSF55729 1 144 3.11E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L14_03900 16f0775ab64917b400c9daca11b6a000 277 Gene3D G3DSA:3.40.630.30 1 147 6.3E-22 T 23-10-2018 A3L14_03900 16f0775ab64917b400c9daca11b6a000 277 Pfam PF13508 Acetyltransferase (GNAT) domain 57 141 1.3E-12 T 23-10-2018 IPR000182 GNAT domain A3L14_06215 dd2b3efed5c5d9e1cf367cafd31e3889 137 SUPERFAMILY SSF81301 11 92 4.28E-15 T 23-10-2018 A3L14_06215 dd2b3efed5c5d9e1cf367cafd31e3889 137 Pfam PF01909 Nucleotidyltransferase domain 20 94 7.2E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L14_06215 dd2b3efed5c5d9e1cf367cafd31e3889 137 Gene3D G3DSA:3.30.460.10 4 95 1.6E-9 T 23-10-2018 A3L14_07100 66666fef785099203573cb57019bfec6 305 Pfam PF16147 Domain of unknown function (DUF4855) 109 283 3.7E-7 T 23-10-2018 IPR032329 Protein of unknown function DUF4855 A3L14_01205 b2f78f22183df1a7680474e0eaa6deab 788 Gene3D G3DSA:3.40.50.12610 481 600 5.2E-14 T 23-10-2018 A3L14_08000 86bb9820869d2ff0ee11e7cfe743b59f 343 SUPERFAMILY SSF52317 47 212 3.2E-9 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_05050 7f401c2061a591e351acd8082d1f1205 99 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 95 9.4E-15 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L14_05050 7f401c2061a591e351acd8082d1f1205 99 Gene3D G3DSA:1.10.287.1080 1 99 4.8E-26 T 23-10-2018 A3L14_05050 7f401c2061a591e351acd8082d1f1205 99 PIRSF PIRSF029904 1 99 6.3E-34 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A3L14_05050 7f401c2061a591e351acd8082d1f1205 99 SUPERFAMILY SSF101386 1 95 4.74E-22 T 23-10-2018 A3L14_09425 05c5aabdc2146a81591fa348546f2dc7 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 5 99 1.7E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_09425 05c5aabdc2146a81591fa348546f2dc7 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 6.1E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_11265 5b3a19136cb1c4beb3d70918ab57e646 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 116 9.0E-26 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L14_06130 327234106d5c7c768a78814d03ec696c 364 Pfam PF05763 Protein of unknown function (DUF835) 233 363 1.0E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_07245 5158170db88acf812cd02fa6bab71899 109 Gene3D G3DSA:3.40.1260.10 1 109 2.8E-14 T 23-10-2018 IPR027396 DsrEFH-like A3L14_07245 5158170db88acf812cd02fa6bab71899 109 SUPERFAMILY SSF75169 1 91 7.46E-7 T 23-10-2018 IPR027396 DsrEFH-like A3L14_04850 6b1070442b11043ecc279ff214cbf2a3 619 Pfam PF00361 Proton-conducting membrane transporter 118 425 1.4E-58 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_02015 10279a19c4ab7d409665a654d85822ff 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 17 85 2.2E-9 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A3L14_02015 10279a19c4ab7d409665a654d85822ff 86 Gene3D G3DSA:3.30.2310.20 5 86 5.3E-17 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_02015 10279a19c4ab7d409665a654d85822ff 86 SUPERFAMILY SSF143011 21 82 2.35E-14 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_08110 f0b43facefa10317c756043dedb95962 254 Pfam PF01061 ABC-2 type transporter 3 216 1.5E-43 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 PIRSF PIRSF006648 1 253 1.5E-69 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_08110 f0b43facefa10317c756043dedb95962 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 4.7E-117 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein A3L14_07760 bc700699268a835452fcaf75bf00edf2 100 Gene3D G3DSA:1.20.120.460 4 99 4.6E-32 T 23-10-2018 IPR038317 Pf1176-like superfamily A3L14_07760 bc700699268a835452fcaf75bf00edf2 100 Pfam PF11505 Protein of unknown function (DUF3216) 8 94 2.6E-30 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A3L14_00325 18a98e1bfe16c393b90943dc5e90f63d 281 Pfam PF13559 Domain of unknown function (DUF4129) 209 272 9.7E-9 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L14_02220 8fc48617aa18dfa54c4517545ba396bb 174 Pfam PF04266 ASCH domain 6 116 4.3E-7 T 23-10-2018 IPR007374 ASCH domain A3L14_02220 8fc48617aa18dfa54c4517545ba396bb 174 SUPERFAMILY SSF88697 3 145 6.13E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L14_02220 8fc48617aa18dfa54c4517545ba396bb 174 SMART SM01022 5 125 1.4E-5 T 23-10-2018 IPR007374 ASCH domain A3L14_10570 d9f8fd48aacfeab3c94db1396d140a42 320 Pfam PF01384 Phosphate transporter family 19 307 3.4E-69 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 5.0E-17 T 23-10-2018 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 SUPERFAMILY SSF54862 3 65 1.28E-14 T 23-10-2018 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 Gene3D G3DSA:3.30.70.20 2 67 3.3E-23 T 23-10-2018 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L14_09905 c1b772d88d9986abb3bd7324f807d245 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 2.2E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L14_09285 cd5760b10a43bb4a168462e960255c34 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 7.1E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L14_09285 cd5760b10a43bb4a168462e960255c34 63 SUPERFAMILY SSF47598 4 46 9.45E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_09285 cd5760b10a43bb4a168462e960255c34 63 Gene3D G3DSA:1.10.1220.10 11 46 1.3E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L14_10155 d5407077ad8a1aad86dc15b87b86b1f5 435 Pfam PF07282 Putative transposase DNA-binding domain 318 387 1.1E-20 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_10155 d5407077ad8a1aad86dc15b87b86b1f5 435 Pfam PF01385 Probable transposase 175 298 1.0E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_10155 d5407077ad8a1aad86dc15b87b86b1f5 435 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 269 345 3.2E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_11445 31628201a68dfbcf7e798d2e78047a66 97 Pfam PF08967 Domain of unknown function (DUF1884) 6 81 3.7E-23 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_11445 31628201a68dfbcf7e798d2e78047a66 97 PIRSF PIRSF004604 2 96 8.5E-30 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_11445 31628201a68dfbcf7e798d2e78047a66 97 SUPERFAMILY SSF111057 6 79 5.49E-23 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L14_11445 31628201a68dfbcf7e798d2e78047a66 97 Gene3D G3DSA:3.30.2320.10 2 80 1.7E-21 T 23-10-2018 A3L14_11445 31628201a68dfbcf7e798d2e78047a66 97 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 7 79 3.0E-20 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L14_09445 fe1e02d9bdbf4b50500e007398dafba4 96 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 94 7.0E-16 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L14_08035 d2d1668d271fad927a9987af8dbe31c4 262 Pfam PF01889 Membrane protein of unknown function DUF63 6 262 2.0E-74 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 Pfam PF00361 Proton-conducting membrane transporter 136 437 3.1E-62 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 9.6E-15 T 23-10-2018 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 9.6E-15 T 23-10-2018 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 9.6E-15 T 23-10-2018 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 9.6E-15 T 23-10-2018 A3L14_11270 0322aba8858f35c70d5a192f36b01736 513 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 75 122 2.7E-10 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_04395 d1b9d0b909cdd5b7d8e3b6a54887a572 286 Gene3D G3DSA:3.40.800.10 3 285 2.8E-73 T 23-10-2018 A3L14_04395 d1b9d0b909cdd5b7d8e3b6a54887a572 286 SUPERFAMILY SSF52768 16 282 9.36E-72 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L14_04395 d1b9d0b909cdd5b7d8e3b6a54887a572 286 Pfam PF00491 Arginase family 23 280 2.3E-60 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L14_04395 d1b9d0b909cdd5b7d8e3b6a54887a572 286 PIRSF PIRSF036979 1 284 3.3E-81 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L14_04395 d1b9d0b909cdd5b7d8e3b6a54887a572 286 TIGRFAM TIGR01230 agmatinase: agmatinase 19 281 1.3E-68 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A3L14_08160 409970c9b0d9391d6796fac364b6afa3 256 SMART SM00518 1 255 1.6E-4 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L14_08160 409970c9b0d9391d6796fac364b6afa3 256 Gene3D G3DSA:3.20.20.150 1 255 1.2E-61 T 23-10-2018 A3L14_08160 409970c9b0d9391d6796fac364b6afa3 256 SUPERFAMILY SSF51658 15 254 1.44E-50 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L14_08160 409970c9b0d9391d6796fac364b6afa3 256 Pfam PF01261 Xylose isomerase-like TIM barrel 22 220 5.5E-33 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L14_08760 78b35238a960aa497fde972671ad1429 71 SUPERFAMILY SSF50182 6 71 3.6E-27 T 23-10-2018 IPR010920 LSM domain superfamily A3L14_08760 78b35238a960aa497fde972671ad1429 71 Gene3D G3DSA:2.30.30.100 2 71 1.6E-28 T 23-10-2018 A3L14_04515 1baf3c6be538b684d33d8b33fd8f66dc 174 Pfam PF06195 Protein of unknown function (DUF996) 22 150 5.9E-29 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L14_10105 21f1fe29a465ff0b2e7f38b8b4e6d9cd 234 Pfam PF07758 Protein of unknown function (DUF1614) 56 233 3.2E-55 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 A3L14_04325 8d77582006c6a8488cee2e9287ff9b85 274 ProDom PD039347 PF1398 MJ0538 PH1392 4 253 3.0E-52 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A3L14_08210 2c386f1243a0cee9ca9f41abd67a915f 184 Pfam PF06197 Protein of unknown function (DUF998) 15 175 1.7E-12 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L14_06360 f6c1ba114bfade358c69beea6602ebb4 235 Pfam PF14358 Domain of unknown function (DUF4405) 14 76 4.7E-16 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A3L14_10640 eee1520f869730bb0ce2d40775222525 255 PIRSF PIRSF006648 1 245 4.8E-18 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L14_10640 eee1520f869730bb0ce2d40775222525 255 Pfam PF01061 ABC-2 type transporter 8 209 1.0E-11 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L14_03465 dfcddb2febc3247edee1c54b3e6a3612 225 Gene3D G3DSA:1.10.150.240 14 83 1.5E-10 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L14_03465 dfcddb2febc3247edee1c54b3e6a3612 225 Gene3D G3DSA:3.40.50.1000 3 152 1.5E-10 T 23-10-2018 IPR023214 HAD superfamily A3L14_03465 dfcddb2febc3247edee1c54b3e6a3612 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 1.3E-10 T 23-10-2018 A3L14_03465 dfcddb2febc3247edee1c54b3e6a3612 225 SUPERFAMILY SSF56784 1 185 3.14E-18 T 23-10-2018 IPR036412 HAD-like superfamily A3L14_09970 481216e82ce2d266e93cb34a7a7a8eb5 260 Pfam PF01435 Peptidase family M48 57 244 8.1E-22 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L14_09970 481216e82ce2d266e93cb34a7a7a8eb5 260 Gene3D G3DSA:3.30.2010.10 49 131 8.6E-19 T 23-10-2018 A3L14_10475 51078576a33c8b9f1a58dd7d17c1ca3f 440 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 347 3.0E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_10475 51078576a33c8b9f1a58dd7d17c1ca3f 440 Pfam PF07282 Putative transposase DNA-binding domain 320 389 1.6E-20 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_10475 51078576a33c8b9f1a58dd7d17c1ca3f 440 Pfam PF01385 Probable transposase 187 300 1.9E-35 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 SUPERFAMILY SSF53187 2 330 1.28E-54 T 23-10-2018 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 2.6E-86 T 23-10-2018 IPR008007 Peptidase M42 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 Gene3D G3DSA:2.40.30.40 64 155 1.1E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 PIRSF PIRSF001123 1 331 3.8E-87 T 23-10-2018 IPR008007 Peptidase M42 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 SUPERFAMILY SSF101821 65 172 1.53E-21 T 23-10-2018 A3L14_05235 e40cdf142b9f46482d1fd136aabe4d94 331 Gene3D G3DSA:3.40.630.10 8 324 1.1E-114 T 23-10-2018 A3L14_03095 e4f997bbe720d5be738edadc571dd7ce 349 Pfam PF01901 Putative O-antigen polymerase 115 307 1.5E-13 T 23-10-2018 IPR002760 Putative O-antigen polymerase A3L14_02730 419c94d180a2f0c16e12e3c54239aeba 108 Gene3D G3DSA:1.10.10.10 2 107 1.1E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_02730 419c94d180a2f0c16e12e3c54239aeba 108 SUPERFAMILY SSF46785 3 106 1.47E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_02730 419c94d180a2f0c16e12e3c54239aeba 108 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 6.5E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L14_05705 05f7404ea01cf2e199254dee3550e767 293 Pfam PF03547 Membrane transport protein 2 130 3.1E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L14_05705 05f7404ea01cf2e199254dee3550e767 293 Pfam PF03547 Membrane transport protein 149 283 6.6E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A3L14_01605 cd04380e9965c7aca733a9db7d9cc161 352 Pfam PF00535 Glycosyl transferase family 2 4 168 1.9E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L14_01605 cd04380e9965c7aca733a9db7d9cc161 352 Gene3D G3DSA:3.90.550.10 1 240 1.3E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_01605 cd04380e9965c7aca733a9db7d9cc161 352 Pfam PF04138 GtrA-like protein 236 351 1.5E-26 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A3L14_01605 cd04380e9965c7aca733a9db7d9cc161 352 SUPERFAMILY SSF53448 2 244 3.18E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L14_07610 994a406072d012aa6c38c113899abf97 434 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 346 4.6E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_07610 994a406072d012aa6c38c113899abf97 434 Pfam PF07282 Putative transposase DNA-binding domain 319 388 2.3E-20 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A3L14_07610 994a406072d012aa6c38c113899abf97 434 Pfam PF01385 Probable transposase 181 299 2.3E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A3L14_08775 d23aefb4f604fa0595fddcaaf9bafb9d 153 Pfam PF01927 Mut7-C RNAse domain 1 144 2.4E-43 T 23-10-2018 IPR002782 Mut7-C RNAse domain A3L14_03485 0ed9d8ecc98942db0fa22f6f6c4a0305 235 Pfam PF13367 Protease prsW family 31 203 7.8E-31 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L14_03485 0ed9d8ecc98942db0fa22f6f6c4a0305 235 PIRSF PIRSF016933 4 222 3.5E-33 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A3L14_05315 e9cdec77fc3df045d3a418e347a4ff6e 156 Hamap MF_00263 UPF0127 protein . 2 116 28.829 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 A3L14_05315 e9cdec77fc3df045d3a418e347a4ff6e 156 Gene3D G3DSA:2.60.120.1140 1 123 1.3E-13 T 23-10-2018 IPR038695 Saro_0823-like superfamily A3L14_05315 e9cdec77fc3df045d3a418e347a4ff6e 156 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 2.8E-17 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A3L14_10800 3c9648347f94001a4d1ed1a64266251d 200 Gene3D G3DSA:3.40.50.150 19 198 1.4E-37 T 23-10-2018 A3L14_10800 3c9648347f94001a4d1ed1a64266251d 200 SUPERFAMILY SSF53335 6 189 2.13E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L14_10800 3c9648347f94001a4d1ed1a64266251d 200 Pfam PF08241 Methyltransferase domain 41 135 1.1E-25 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L14_10800 3c9648347f94001a4d1ed1a64266251d 200 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A3L14_01630 a7bb89c4dba5ee1ca65ad8223c9ef4a9 113 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 1.5E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_01630 a7bb89c4dba5ee1ca65ad8223c9ef4a9 113 Gene3D G3DSA:1.10.10.10 1 109 8.7E-37 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_01630 a7bb89c4dba5ee1ca65ad8223c9ef4a9 113 SUPERFAMILY SSF46785 3 105 5.88E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_04490 1c4369fcd88d1ec9eb626dbed1050e45 428 SUPERFAMILY SSF52540 29 221 9.16E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_04490 1c4369fcd88d1ec9eb626dbed1050e45 428 Pfam PF13173 AAA domain 35 167 2.8E-38 T 23-10-2018 A3L14_04490 1c4369fcd88d1ec9eb626dbed1050e45 428 Gene3D G3DSA:3.40.50.300 69 154 5.9E-7 T 23-10-2018 A3L14_04490 1c4369fcd88d1ec9eb626dbed1050e45 428 Pfam PF13635 Domain of unknown function (DUF4143) 227 366 6.2E-9 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L14_07700 068428f73b5f16103d210a1c2527d595 65 Pfam PF01954 Protein of unknown function DUF104 1 59 4.7E-11 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L14_05575 15ad11e0a64f6840d15cb92d2220af4c 302 Pfam PF01384 Phosphate transporter family 11 294 1.0E-49 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L14_05995 e708be62fa7b64853b05c2347d3f8e2d 369 Pfam PF04473 Transglutaminase-like domain 21 218 6.6E-25 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L14_01105 2f1b1c010fa3b0ce9515dcec58016e1a 435 Pfam PF01882 Protein of unknown function DUF58 182 258 7.9E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L14_01105 2f1b1c010fa3b0ce9515dcec58016e1a 435 Gene3D G3DSA:3.40.50.410 213 399 5.3E-5 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A3L14_11245 70ab00289fbbd918c762d7a215cc516c 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 1.5E-33 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_11245 70ab00289fbbd918c762d7a215cc516c 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 3.4E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L14_09495 2f3ec3fe6a6d071159c753df412fe329 47 SMART SM00355 18 41 0.0055 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L14_09495 2f3ec3fe6a6d071159c753df412fe329 47 SUPERFAMILY SSF57667 13 42 1.24E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily A3L14_09495 2f3ec3fe6a6d071159c753df412fe329 47 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L14_10430 9069e6ef7dca524a8c233b1f0d9a9450 429 SUPERFAMILY SSF111283 2 423 1.11E-82 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L14_10430 9069e6ef7dca524a8c233b1f0d9a9450 429 Pfam PF01523 Putative modulator of DNA gyrase 15 304 2.1E-47 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L14_10430 9069e6ef7dca524a8c233b1f0d9a9450 429 Gene3D G3DSA:3.30.2290.10 1 208 1.2E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L14_11405 4e71e9beb93f64ea56288cbb58227a9d 402 SUPERFAMILY SSF52540 60 300 1.5E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L14_11405 4e71e9beb93f64ea56288cbb58227a9d 402 Gene3D G3DSA:3.40.50.300 46 235 6.6E-10 T 23-10-2018 A3L14_01360 708544f18f32d937fed83610de5410dd 119 Gene3D G3DSA:2.30.30.110 25 119 7.5E-21 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L14_01360 708544f18f32d937fed83610de5410dd 119 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 115 2.0E-17 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L14_01360 708544f18f32d937fed83610de5410dd 119 SUPERFAMILY SSF50118 7 118 7.85E-22 T 23-10-2018 A3L14_01555 4ae5ffc56e8a38b52c3199f106b364e6 340 Pfam PF17231 Family of unknown function (DUF5305) 125 328 1.4E-13 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L14_03725 565556773b79725aa3dc943af15979eb 307 SUPERFAMILY SSF53795 105 179 1.22E-5 T 23-10-2018 A3L14_04865 4bcf60e0be034c9a86cd4c4a2d69b569 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 7.2E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L14_06400 c14594be68e3b2c154e5c993efc65248 290 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 1.4E-8 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L14_07885 d2b590f3fd7c237bc3eec69131aeb02f 572 Pfam PF00482 Type II secretion system (T2SS), protein F 88 215 4.2E-7 T 23-10-2018 IPR018076 Type II secretion system F domain A3L14_07885 d2b590f3fd7c237bc3eec69131aeb02f 572 Pfam PF00482 Type II secretion system (T2SS), protein F 337 462 1.7E-7 T 23-10-2018 IPR018076 Type II secretion system F domain A3L14_04860 3bfcfb5a937e040a2296719366486fab 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 3.3E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L14_07175 1bc14265b07318bfb4409a29a80c1de9 176 Pfam PF06197 Protein of unknown function (DUF998) 9 174 1.9E-24 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L14_08500 6ae6a47c5e4d317aafdbd8a332031acf 141 Pfam PF05763 Protein of unknown function (DUF835) 30 138 3.7E-21 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_08450 1288bc1369ab67e5ec7b4f0ece62a2e4 149 Pfam PF01986 Domain of unknown function DUF123 26 110 2.6E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A3L14_08450 1288bc1369ab67e5ec7b4f0ece62a2e4 149 SMART SM00465 18 113 1.7E-6 T 23-10-2018 IPR000305 GIY-YIG endonuclease A3L14_04755 c2017956865ea28046b6920300a62465 270 SUPERFAMILY SSF100950 12 120 1.88E-6 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L14_04000 2a6e8952ff8e892f0c4bdb1a7a9e87b4 273 Gene3D G3DSA:1.25.40.10 62 254 9.5E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_04045 d4478ea2a4419cc6f274e7b85bbd3ebe 244 Gene3D G3DSA:3.40.50.300 8 239 2.3E-60 T 23-10-2018 A3L14_10535 66b8e0ed23f32c9c03a1df7bdd671e53 343 SUPERFAMILY SSF48452 130 323 2.15E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_10535 66b8e0ed23f32c9c03a1df7bdd671e53 343 Gene3D G3DSA:1.25.40.10 117 335 4.9E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_10535 66b8e0ed23f32c9c03a1df7bdd671e53 343 Pfam PF13429 Tetratricopeptide repeat 165 312 3.4E-7 T 23-10-2018 A3L14_09140 7b51334fe8c37fa504045be8c46be392 299 Pfam PF05763 Protein of unknown function (DUF835) 167 262 1.1E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_03280 297ed041f05d7295e81a6095397dd161 219 Pfam PF02361 Cobalt transport protein 27 193 2.8E-25 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L14_11160 cbfb3195da11dd49bff6290d45e8ab96 359 Gene3D G3DSA:1.25.40.10 1 359 3.3E-87 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_11160 cbfb3195da11dd49bff6290d45e8ab96 359 SUPERFAMILY SSF48452 16 189 9.7E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_09990 57d141e067518c88970fe73fd67685cd 302 Pfam PF00953 Glycosyl transferase family 4 67 215 1.5E-33 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A3L14_10015 9fa1b4bb6314be1b10b653177660c4e7 163 SUPERFAMILY SSF48452 13 98 2.02E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_10015 9fa1b4bb6314be1b10b653177660c4e7 163 Gene3D G3DSA:1.25.40.10 15 160 2.5E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_08490 e053640ae7585d761cf0014619e544a6 219 Pfam PF02616 Segregation and condensation protein ScpA 18 161 1.8E-13 T 23-10-2018 IPR003768 Segregation and condensation protein A A3L14_08490 e053640ae7585d761cf0014619e544a6 219 Gene3D G3DSA:1.10.10.580 147 216 1.6E-31 T 23-10-2018 IPR023093 ScpA-like, C-terminal A3L14_05840 79079ce55ec2940805f14f5c920ccf4f 98 Gene3D G3DSA:3.40.50.1010 1 92 2.4E-15 T 23-10-2018 A3L14_05840 79079ce55ec2940805f14f5c920ccf4f 98 SUPERFAMILY SSF88723 3 96 3.36E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L14_00300 4d4e1e7847ee6669fa557f28b7dcecd3 354 Gene3D G3DSA:1.20.81.30 178 285 4.2E-12 T 23-10-2018 A3L14_00300 4d4e1e7847ee6669fa557f28b7dcecd3 354 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 1.6E-23 T 23-10-2018 IPR018076 Type II secretion system F domain A3L14_06540 3077cbf346a48aaf0fa943581596798c 257 Pfam PF13559 Domain of unknown function (DUF4129) 184 248 2.0E-5 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L14_05875 4675305d4e2fd39c2b96d1196a31e502 86 Gene3D G3DSA:3.30.2310.20 1 84 2.0E-22 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_05875 4675305d4e2fd39c2b96d1196a31e502 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 82 7.8E-9 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A3L14_05875 4675305d4e2fd39c2b96d1196a31e502 86 SUPERFAMILY SSF143011 1 82 9.03E-23 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_05295 6ad18aa2997f06c4e904ae8424b4dee3 92 SUPERFAMILY SSF143011 2 82 5.49E-21 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_05295 6ad18aa2997f06c4e904ae8424b4dee3 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 83 3.3E-9 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A3L14_05295 6ad18aa2997f06c4e904ae8424b4dee3 92 Gene3D G3DSA:3.30.2310.20 1 90 8.3E-21 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A3L14_05320 52dca1c32c3db1b7a02fad4203604bf5 186 Gene3D G3DSA:3.40.920.10 1 185 1.7E-53 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_05320 52dca1c32c3db1b7a02fad4203604bf5 186 SUPERFAMILY SSF53323 2 180 1.29E-39 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L14_05320 52dca1c32c3db1b7a02fad4203604bf5 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.5E-32 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L14_01490 15bac0edff9c0bb3f9c71437b56519aa 208 Pfam PF04021 Class III signal peptide 3 29 1.1E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L14_07200 b42aaf1ef768c65903cea4c1156fa6f8 366 Pfam PF01458 Uncharacterized protein family (UPF0051) 130 338 1.3E-29 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L14_07200 b42aaf1ef768c65903cea4c1156fa6f8 366 SUPERFAMILY SSF101960 9 344 5.49E-39 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L14_06060 e612de2e820488aaa10009ca83a432d0 231 Pfam PF02654 Cobalamin-5-phosphate synthase 5 222 6.2E-40 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L14_06060 e612de2e820488aaa10009ca83a432d0 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 30.12 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L14_06060 e612de2e820488aaa10009ca83a432d0 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 2.4E-45 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L14_11120 4c7196366ca2262ef168bc5b4f84841e 318 Gene3D G3DSA:3.40.1350.10 189 299 1.0E-6 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L14_04170 1d0541871af3dc04f6df996eba35a580 331 Pfam PF01594 AI-2E family transporter 10 322 1.5E-41 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L14_01730 e8546a82de0599a9f3951f380ddfbd43 317 Gene3D G3DSA:1.25.10.10 1 254 2.7E-88 T 23-10-2018 IPR011989 Armadillo-like helical A3L14_01730 e8546a82de0599a9f3951f380ddfbd43 317 SUPERFAMILY SSF48371 25 223 3.96E-12 T 23-10-2018 IPR016024 Armadillo-type fold A3L14_09380 f12c8631fdb211555325ea6bc4378af2 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 16 197 1.9E-12 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L14_09380 f12c8631fdb211555325ea6bc4378af2 212 Gene3D G3DSA:3.40.50.11570 6 207 3.8E-15 T 23-10-2018 A3L14_06695 d1c8961560d81712f7b5c3a2d13ec114 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 3.4E-27 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 A3L14_09030 b76d3836e3d13f83dcf013b0a374ca50 427 Gene3D G3DSA:1.25.40.10 260 410 2.6E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_09030 b76d3836e3d13f83dcf013b0a374ca50 427 Gene3D G3DSA:1.25.40.10 3 218 3.0E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L14_07320 9b0212a8e4d78ff3d8d898cd8623e891 119 SUPERFAMILY SSF117916 16 59 5.56E-6 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L14_07320 9b0212a8e4d78ff3d8d898cd8623e891 119 Pfam PF01883 Iron-sulfur cluster assembly protein 15 56 2.3E-6 T 23-10-2018 IPR002744 MIP18 family-like A3L14_06935 7c285a341edec498819c79dbc1775024 816 SUPERFAMILY SSF63825 27 235 2.22E-9 T 23-10-2018 A3L14_05885 164961c0ef99d9c153520f1956692209 124 SMART SM00748 7 113 4.4E-22 T 23-10-2018 IPR007842 HEPN domain A3L14_05885 164961c0ef99d9c153520f1956692209 124 Pfam PF05168 HEPN domain 4 119 2.6E-34 T 23-10-2018 IPR007842 HEPN domain A3L14_05885 164961c0ef99d9c153520f1956692209 124 Gene3D G3DSA:1.20.120.330 2 122 9.1E-36 T 23-10-2018 A3L14_05885 164961c0ef99d9c153520f1956692209 124 SUPERFAMILY SSF81593 6 120 7.46E-31 T 23-10-2018 A3L14_09080 a9244f88e430da266c07a41a3794853b 337 SUPERFAMILY SSF46785 4 98 1.15E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_09080 a9244f88e430da266c07a41a3794853b 337 Gene3D G3DSA:1.10.10.10 3 102 5.9E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L14_09080 a9244f88e430da266c07a41a3794853b 337 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 335 9.0E-45 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L14_09080 a9244f88e430da266c07a41a3794853b 337 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 76 1.9E-20 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L14_09080 a9244f88e430da266c07a41a3794853b 337 SUPERFAMILY SSF159071 248 336 3.66E-20 T 23-10-2018 A3L14_05645 3bf98f349de915277300a71cf1063a4e 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 1.7E-120 T 23-10-2018 IPR008482 Protein of unknown function DUF763 A3L14_05735 27939404f51954cab1de86379eb5557d 217 Pfam PF13349 Putative adhesin 7 185 4.8E-8 T 23-10-2018 IPR025164 Putative adhesin A3L14_02275 a54eda328ea90506b7073508bbc33509 164 Pfam PF05916 GINS complex protein 27 147 1.3E-7 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A3L14_02275 a54eda328ea90506b7073508bbc33509 164 Gene3D G3DSA:1.20.58.2050 1 164 1.0E-81 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L14_04815 4cf4d7855de9452f50f407f52a802e07 212 Pfam PF06195 Protein of unknown function (DUF996) 33 184 2.2E-27 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L14_07770 643bf0018066c43f4b254f13d472c788 515 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 6 503 1.6E-97 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A3L14_07770 643bf0018066c43f4b254f13d472c788 515 SUPERFAMILY SSF51717 161 386 1.31E-23 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_07770 643bf0018066c43f4b254f13d472c788 515 Gene3D G3DSA:3.20.20.20 166 322 3.1E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L14_06435 d43c76fef3a72d85a9be9adacd58d523 59 SUPERFAMILY SSF47113 5 59 4.37E-6 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L14_02040 d383959986927987a90485f57c2dbaed 488 Pfam PF05124 S-layer like family, C-terminal region 383 487 2.6E-9 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L14_01200 fbb294c0f617da137f87aef115163752 75 SUPERFAMILY SSF47598 7 49 1.1E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L14_05250 aff2a1e3a39bdefd54ef162a3d6e4f17 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 2.1E-58 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L14_06065 399345b2de7276ab988e4db476b761e7 69 Pfam PF10047 Protein of unknown function (DUF2281) 4 60 1.8E-15 T 23-10-2018 IPR018739 Domain of unknown function DUF2281 A3L14_11365 0bd4ff219ca7d89770f60b9e67c1e2b1 321 Pfam PF00146 NADH dehydrogenase 17 317 6.0E-65 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_11365 0bd4ff219ca7d89770f60b9e67c1e2b1 321 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 200 213 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L14_03220 166c09a54f3b4d2389f78c53663105b6 233 Pfam PF01963 TraB family 9 223 1.4E-14 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A3L14_10480 a85b7bf199d25123d1d58e2b120d4d16 128 Gene3D G3DSA:1.20.1260.10 1 102 1.5E-6 T 23-10-2018 IPR012347 Ferritin-like A3L14_02035 f7fe1c6772c903bdbee8029ff3b3f79f 170 Pfam PF09622 Putative integral membrane protein (DUF2391) 34 163 1.6E-9 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 A3L14_01070 7b2dfe8e336d0816dd1a828efda95898 198 Pfam PF12389 Camelysin metallo-endopeptidase 8 198 7.8E-8 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L14_09615 5469b76cbf91ad32d3c7b370fe82a9d7 281 Pfam PF07722 Peptidase C26 3 219 2.3E-52 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A3L14_09615 5469b76cbf91ad32d3c7b370fe82a9d7 281 Gene3D G3DSA:3.40.50.880 1 246 4.0E-66 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_09615 5469b76cbf91ad32d3c7b370fe82a9d7 281 SUPERFAMILY SSF52317 2 239 4.58E-33 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L14_10780 fa3a5d2167d7090de1954622fa739f8d 529 Pfam PF08308 PEGA domain 383 448 5.8E-6 T 23-10-2018 IPR013229 PEGA A3L14_01460 8b4a7bb5ed4af2d8e0f0f451a3931457 248 Pfam PF09874 Predicted membrane protein (DUF2101) 23 228 1.4E-79 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A3L14_03695 3228d5834c8c9a95580cd4dbbd9472da 106 Gene3D G3DSA:2.60.120.10 3 106 1.1E-36 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L14_03695 3228d5834c8c9a95580cd4dbbd9472da 106 Pfam PF07883 Cupin domain 36 102 1.4E-12 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L14_03695 3228d5834c8c9a95580cd4dbbd9472da 106 SUPERFAMILY SSF51182 5 104 4.75E-26 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L14_08095 741f3908b080eca5f6c7fc792f914e7b 712 SUPERFAMILY SSF52980 20 128 1.23E-8 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_08095 741f3908b080eca5f6c7fc792f914e7b 712 Pfam PF04471 Restriction endonuclease 20 124 2.7E-15 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A3L14_04960 e95c0a4bcb29273394e1e98de2992796 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 9 77 5.8E-7 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A3L14_03125 2fd1d81d75df023c8dadb2cf60b4b17b 480 SUPERFAMILY SSF81324 393 479 3.01E-16 T 23-10-2018 A3L14_03125 2fd1d81d75df023c8dadb2cf60b4b17b 480 Gene3D G3DSA:1.10.287.70 394 480 1.3E-13 T 23-10-2018 A3L14_03125 2fd1d81d75df023c8dadb2cf60b4b17b 480 Pfam PF07885 Ion channel 405 479 1.2E-14 T 23-10-2018 IPR013099 Potassium channel domain A3L14_03560 ce342938773a7141468845f3b36c54ec 429 SUPERFAMILY SSF161070 13 354 2.22E-8 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L14_10315 bedaf3390533fc655eed350f6e3d3fb9 109 Pfam PF04892 VanZ like family 30 92 1.0E-8 T 23-10-2018 IPR006976 VanZ-like A3L14_05260 e884feba381d07887dfe05a42f7ac41a 243 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 5.7E-57 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L14_03085 e22b0be28a835854862b0b000f20784d 462 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 53 213 6.8E-17 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L14_03825 a93c3de1be92493e488c3e2e4b6b1a37 99 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 8 40 5.7E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A3L14_04990 2b69e1b05ca97bd59cad9ce83179b8cf 386 Pfam PF04412 Protein of unknown function (DUF521) 1 382 2.7E-148 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A3L14_11260 ecd73c2237a62eb325d73b7680bb8036 144 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 4 130 5.7E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L14_04770 87594543c1fdef25591a24117ee70dd9 361 SUPERFAMILY SSF52980 243 326 8.71E-7 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L14_06615 74e54aac6388f3cdd64e918d5b35ab4e 120 Pfam PF03008 Archaea bacterial proteins of unknown function 12 56 5.0E-15 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L14_09055 80b0c206facffe81a47ec79112a105ac 215 Pfam PF01863 Protein of unknown function DUF45 10 196 1.3E-49 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A3L14_09055 80b0c206facffe81a47ec79112a105ac 215 Gene3D G3DSA:3.30.2010.10 106 200 2.4E-21 T 23-10-2018 A3L14_03870 9773467dc5ad06d8b3a6d340244a20e8 680 Pfam PF05753 Translocon-associated protein beta (TRAPB) 332 436 6.4E-8 T 23-10-2018 A3L14_00495 f40d4163fa39ba9fe095a92f35878457 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 3.8E-56 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L14_00495 f40d4163fa39ba9fe095a92f35878457 391 Gene3D G3DSA:1.20.1530.20 1 391 1.4E-76 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L14_04645 a4946232ba0bd0f33c6804d428096014 92 Gene3D G3DSA:3.30.310.50 7 92 2.4E-25 T 23-10-2018 A3L14_04645 a4946232ba0bd0f33c6804d428096014 92 Pfam PF09341 Transcription factor Pcc1 20 90 3.3E-13 T 23-10-2018 IPR015419 CTAG/Pcc1 family A3L14_02105 39cc15ce5c93cad59612839cbd69ad03 347 Pfam PF01594 AI-2E family transporter 12 322 7.9E-37 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L14_01575 c407c7486e817bc398ba0738d5bc8633 177 Pfam PF06510 Protein of unknown function (DUF1102) 38 174 9.0E-43 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L14_01890 d813e3d3874da1108c9e73aa25eb38da 348 Pfam PF05763 Protein of unknown function (DUF835) 221 345 2.2E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L14_01175 60a01494ec7ca8af398191e489eb2cd7 71 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 2.1E-19 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 A3L14_01235 02682f8838805e0f06feedc4d69b2acd 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 A3L14_01465 bf058c6e8f5da42e31dbdbc6e67ad455 1124 Pfam PF10102 Domain of unknown function (DUF2341) 580 657 1.7E-10 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L14_05460 de10d32fa6c6d232f261253417b28427 200 Pfam PF02517 CAAX protease self-immunity 114 188 4.2E-9 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L14_00625 645106cb6e2ecc42c21ef6222a233877 344 Pfam PF17231 Family of unknown function (DUF5305) 119 335 6.0E-33 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L14_06585 1ef3a4b37747d7c0b16ffbe60bf9b0b0 273 Pfam PF00950 ABC 3 transport family 4 266 1.7E-28 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A3L14_06585 1ef3a4b37747d7c0b16ffbe60bf9b0b0 273 SUPERFAMILY SSF81345 3 272 2.22E-19 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L14_06585 1ef3a4b37747d7c0b16ffbe60bf9b0b0 273 Gene3D G3DSA:1.10.3470.10 39 273 1.1E-5 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L14_11185 b161890d08bafdf2fb357fa0e321c5aa 215 SUPERFAMILY SSF56112 8 154 7.11E-13 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L14_01365 7ab9894884a68579b1ffc5113eabbdbb 162 Pfam PF11848 Domain of unknown function (DUF3368) 113 155 1.6E-7 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 A3L14_06275 4327d8781e6d2ff14c28c5c1255f950b 308 Pfam PF12679 ABC-2 family transporter protein 5 307 5.8E-58 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L14_05040 e0ad50a6f9a6516ade83c28788dc2528 237 Pfam PF01940 Integral membrane protein DUF92 11 215 1.2E-49 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A3L14_00340 b0b58b0a86ffb21bdcab772010dec381 408 Pfam PF01882 Protein of unknown function DUF58 188 267 8.8E-21 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L14_05335 ae4a1c7290e72aceca2ce54913f60c34 68 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 1.4E-11 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 A3L14_00565 b2f7de1f811936d7d6b7d5b2a6187aa8 204 Pfam PF01914 MarC family integral membrane protein 7 196 3.6E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L14_01590 cd93454aff1a9de5c682cb58c334a949 71 SUPERFAMILY SSF46785 8 70 5.33E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L14_11335 4f675659854f9836fa28d83a915025f1 117 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 113 1.3E-28 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L14_11330 10f2ef96ee2b09bfa36b3fb61acd265f 155 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 5 139 1.6E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L14_02330 ff94a993cef33041f7010698fb59f314 81 Pfam PF03683 Uncharacterised protein family (UPF0175) 5 77 2.1E-26 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 A3L14_07615 1ecc9142df2d9c147bb7f165b42bd413 193 Pfam PF06197 Protein of unknown function (DUF998) 14 179 9.0E-21 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L14_03320 39262e716b3931e417a21bd8526210fa 191 SUPERFAMILY SSF47240 9 181 1.53E-7 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L14_08830 a2a1648df4dd52a02619c11d1347fa7b 232 Pfam PF02517 CAAX protease self-immunity 98 184 6.6E-9 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L14_10655 148dd69a971f97253f7c7267ca994c0a 197 PIRSF PIRSF004897 1 165 2.8E-45 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type