THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 SUPERFAMILY SSF52172 1 126 1.42E-38 T 12-10-2018 IPR011006 CheY-like superfamily THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 SMART SM00862 148 219 9.7E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 Gene3D G3DSA:1.10.10.10 128 222 4.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 Gene3D G3DSA:3.40.50.2300 1 127 2.0E-36 T 12-10-2018 THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 219 5.3E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 SUPERFAMILY SSF46894 129 220 2.75E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 SMART SM00448 1 114 5.0E-40 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_07940 998f1c15e7a6856077fdec48cbb4ffc1 222 Pfam PF00072 Response regulator receiver domain 3 115 6.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 PIRSF PIRSF000151 1 427 2.0E-180 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 Pfam PF00171 Aldehyde dehydrogenase family 8 281 1.7E-12 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 Gene3D G3DSA:3.40.309.10 228 384 5.8E-162 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 7 426 41.154 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 SUPERFAMILY SSF53720 8 426 1.23E-111 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 15 415 5.4E-149 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 Gene3D G3DSA:3.40.605.10 20 421 5.8E-162 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THERU_01225 420fb6f010834e5158c67c81cf1eab89 441 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 333 355 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_08045 425c62ef563f45b0be970f25377652d0 527 SUPERFAMILY SSF110921 405 515 1.11E-22 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_08045 425c62ef563f45b0be970f25377652d0 527 Gene3D G3DSA:3.20.20.70 4 327 1.2E-117 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_08045 425c62ef563f45b0be970f25377652d0 527 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 518 5.3E-28 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_08045 425c62ef563f45b0be970f25377652d0 527 SUPERFAMILY SSF51569 1 294 7.33E-89 T 12-10-2018 THERU_08045 425c62ef563f45b0be970f25377652d0 527 Gene3D G3DSA:3.30.160.270 329 516 1.1E-9 T 12-10-2018 THERU_08045 425c62ef563f45b0be970f25377652d0 527 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_08045 425c62ef563f45b0be970f25377652d0 527 SMART SM00917 376 519 1.1E-41 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_08045 425c62ef563f45b0be970f25377652d0 527 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 526 2.7E-275 T 12-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 THERU_08045 425c62ef563f45b0be970f25377652d0 527 Pfam PF00682 HMGL-like 4 277 3.5E-50 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THERU_00140 8f416a5ea08638a68f4245731ae8e6e8 141 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 8 110 2.3E-22 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 THERU_00140 8f416a5ea08638a68f4245731ae8e6e8 141 SUPERFAMILY SSF52540 6 105 3.45E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00140 8f416a5ea08638a68f4245731ae8e6e8 141 Gene3D G3DSA:3.40.50.300 6 139 5.2E-31 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 Pfam PF00361 Proton-conducting membrane transporter 130 418 3.1E-83 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 4.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 259 281 4.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 4.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 32 51 4.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 410 432 4.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 59 118 8.0E-13 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 603 6.0E-186 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 7.8E-52 T 12-10-2018 THERU_02470 f1962cd14ec9b3dac6b832d5e2d0882c 609 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 411 430 7.8E-52 T 12-10-2018 THERU_00420 fec60c8eb974578c0059c434d6a26b70 109 SUPERFAMILY SSF81301 1 108 1.29E-36 T 12-10-2018 THERU_00420 fec60c8eb974578c0059c434d6a26b70 109 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 4 101 7.6E-35 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THERU_00420 fec60c8eb974578c0059c434d6a26b70 109 Gene3D G3DSA:3.30.460.10 1 109 1.5E-35 T 12-10-2018 THERU_00420 fec60c8eb974578c0059c434d6a26b70 109 Pfam PF02410 Ribosomal silencing factor during starvation 6 101 3.1E-27 T 12-10-2018 THERU_00420 fec60c8eb974578c0059c434d6a26b70 109 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 102 22.569 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THERU_07320 e32433aced156b39ef858e183b76acdf 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 1.3E-28 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 SUPERFAMILY SSF54980 601 688 2.64E-31 T 12-10-2018 IPR035647 EF-G domain III/V-like THERU_07320 e32433aced156b39ef858e183b76acdf 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site THERU_07320 e32433aced156b39ef858e183b76acdf 695 Pfam PF03144 Elongation factor Tu domain 2 323 389 4.4E-14 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 SUPERFAMILY SSF54980 400 478 9.71E-26 T 12-10-2018 IPR035647 EF-G domain III/V-like THERU_07320 e32433aced156b39ef858e183b76acdf 695 Gene3D G3DSA:3.30.70.240 602 672 1.9E-98 T 12-10-2018 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 5.9E-67 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 111.821 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_07320 e32433aced156b39ef858e183b76acdf 695 SUPERFAMILY SSF54211 477 597 5.56E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_07320 e32433aced156b39ef858e183b76acdf 695 Pfam PF00679 Elongation factor G C-terminus 598 684 2.6E-33 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like THERU_07320 e32433aced156b39ef858e183b76acdf 695 SUPERFAMILY SSF52540 6 281 5.12E-108 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07320 e32433aced156b39ef858e183b76acdf 695 Gene3D G3DSA:3.30.70.870 404 481 7.5E-33 T 12-10-2018 THERU_07320 e32433aced156b39ef858e183b76acdf 695 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.8E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 SMART SM00838 598 685 1.5E-57 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like THERU_07320 e32433aced156b39ef858e183b76acdf 695 SMART SM00889 478 596 9.0E-77 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 SUPERFAMILY SSF50447 247 399 1.11E-34 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07320 e32433aced156b39ef858e183b76acdf 695 Gene3D G3DSA:3.40.50.300 2 292 6.6E-114 T 12-10-2018 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Gene3D G3DSA:3.30.230.10 482 685 1.9E-98 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_07320 e32433aced156b39ef858e183b76acdf 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Pfam PF03764 Elongation factor G, domain IV 477 596 5.1E-50 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Pfam PF14492 Elongation Factor G, domain II 402 476 5.4E-36 T 12-10-2018 THERU_07320 e32433aced156b39ef858e183b76acdf 695 Gene3D G3DSA:2.40.30.10 293 403 1.1E-40 T 12-10-2018 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 383 403 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Gene3D G3DSA:3.40.50.170 20 161 5.7E-19 T 12-10-2018 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Pfam PF02911 Formyl transferase, C-terminal domain 171 256 9.4E-12 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 SUPERFAMILY SSF53328 6 153 3.53E-26 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Gene3D G3DSA:3.90.226.10 282 482 6.5E-35 T 12-10-2018 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 PIRSF PIRSF006787 1 562 5.8E-262 T 12-10-2018 IPR009188 [NiFe]-hydrogenase maturation factor, HypX/HoxX type THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Pfam PF00378 Enoyl-CoA hydratase/isomerase 306 518 1.3E-21 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Gene3D G3DSA:3.10.25.10 172 264 3.7E-8 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 SUPERFAMILY SSF50486 172 254 1.28E-12 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 Pfam PF00551 Formyl transferase 39 120 9.3E-6 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_04805 58aee484d3d1012508a6e92c3d9ed13e 562 SUPERFAMILY SSF52096 285 540 5.88E-38 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 SUPERFAMILY SSF55957 360 454 5.36E-19 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 244 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 201 214 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 SUPERFAMILY SSF53738 149 251 8.24E-21 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 134 5.6E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 366 2.1E-25 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Gene3D G3DSA:3.30.310.50 369 455 5.6E-25 T 12-10-2018 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 399 452 2.1E-11 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 SUPERFAMILY SSF53738 237 373 3.14E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Gene3D G3DSA:3.40.120.10 169 249 1.6E-20 T 12-10-2018 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 150 249 1.6E-21 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 SUPERFAMILY SSF53738 2 163 6.28E-41 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Gene3D G3DSA:3.40.120.10 250 368 5.6E-34 T 12-10-2018 THERU_00395 e555ad8750ae35a0a149b0792f27aaec 455 Gene3D G3DSA:3.40.120.10 1 160 5.4E-47 T 12-10-2018 THERU_03290 eb5dd7d194472d70e80493e6883dc64c 115 SUPERFAMILY SSF55620 2 113 9.45E-31 T 12-10-2018 THERU_03290 eb5dd7d194472d70e80493e6883dc64c 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 113 3.4E-26 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THERU_03290 eb5dd7d194472d70e80493e6883dc64c 115 PIRSF PIRSF006113 1 115 3.5E-23 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THERU_03290 eb5dd7d194472d70e80493e6883dc64c 115 Gene3D G3DSA:3.30.479.10 71 115 9.1E-10 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THERU_03290 eb5dd7d194472d70e80493e6883dc64c 115 Gene3D G3DSA:3.30.479.10 4 70 1.0E-13 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 Pfam PF00437 Type II/IV secretion system protein 97 362 3.3E-82 T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 SMART SM00382 223 346 4.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 Gene3D G3DSA:3.40.50.300 197 467 2.5E-120 T 12-10-2018 THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 290 304 - T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 SUPERFAMILY SSF160246 2 59 2.62E-6 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 2 65 7.4E-6 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 Gene3D G3DSA:3.30.450.90 59 195 2.6E-47 T 12-10-2018 THERU_01255 b5385dd6a02f7c9e7dda495d5e9e3c88 469 SUPERFAMILY SSF52540 86 465 7.43E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07910 89e16fab96a75196f5a94d5dfd562959 181 SUPERFAMILY SSF48452 44 157 1.28E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_07910 89e16fab96a75196f5a94d5dfd562959 181 Pfam PF13414 TPR repeat 46 82 5.2E-8 T 12-10-2018 THERU_07910 89e16fab96a75196f5a94d5dfd562959 181 Gene3D G3DSA:1.25.40.10 39 170 2.0E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Gene3D G3DSA:3.90.1640.10 2 175 2.4E-25 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Gene3D G3DSA:3.10.580.10 287 420 2.1E-24 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Pfam PF02272 DHHA1 domain 158 283 2.2E-8 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Gene3D G3DSA:1.10.3090.10 571 813 4.6E-48 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Pfam PF00571 CBS domain 358 411 3.2E-8 T 12-10-2018 IPR000644 CBS domain THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Pfam PF00571 CBS domain 296 347 5.8E-8 T 12-10-2018 IPR000644 CBS domain THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Pfam PF01743 Poly A polymerase head domain 450 575 1.8E-34 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 Gene3D G3DSA:3.30.460.10 423 570 1.5E-53 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SMART SM00116 303 351 1.1E-5 T 12-10-2018 IPR000644 CBS domain THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SMART SM00116 365 412 0.024 T 12-10-2018 IPR000644 CBS domain THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SUPERFAMILY SSF81301 439 572 5.12E-39 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SUPERFAMILY SSF64182 3 277 1.83E-39 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SUPERFAMILY SSF54631 294 414 6.06E-27 T 12-10-2018 THERU_03555 ba86b1887916b6d9f95d9a7225470d50 815 SUPERFAMILY SSF81891 573 780 7.85E-33 T 12-10-2018 THERU_08075 e162ad23afa21de1b1839720bc98bfe6 181 Gene3D G3DSA:1.20.1220.20 6 167 3.2E-20 T 12-10-2018 THERU_08075 e162ad23afa21de1b1839720bc98bfe6 181 Pfam PF01724 Domain of unknown function DUF29 12 165 3.7E-36 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_03990 07053fe19a86ffb79a0f2b7b5007ec17 78 Gene3D G3DSA:1.25.40.10 3 78 2.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03990 07053fe19a86ffb79a0f2b7b5007ec17 78 SUPERFAMILY SSF48452 18 66 3.94E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03990 07053fe19a86ffb79a0f2b7b5007ec17 78 Pfam PF14559 Tetratricopeptide repeat 23 66 1.8E-5 T 12-10-2018 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 Gene3D G3DSA:3.10.430.100 63 148 2.6E-30 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 SUPERFAMILY SSF55653 57 147 1.18E-27 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 145 7.8E-29 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 6.3E-21 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.544 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 2.1E-42 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 Gene3D G3DSA:3.40.5.10 1 62 1.5E-20 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07865 cbe5937c44d46688a31a3f42b94a34ad 148 SUPERFAMILY SSF55658 1 56 2.62E-16 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal THERU_01865 56aa13583ac113d2129f368a2976710b 473 SUPERFAMILY SSF48024 9 119 1.07E-15 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 THERU_01865 56aa13583ac113d2129f368a2976710b 473 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 12 441 2.8E-143 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 THERU_01865 56aa13583ac113d2129f368a2976710b 473 Pfam PF03796 DnaB-like helicase C terminal domain 184 439 1.3E-104 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 THERU_01865 56aa13583ac113d2129f368a2976710b 473 Gene3D G3DSA:1.10.860.10 4 165 9.6E-24 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THERU_01865 56aa13583ac113d2129f368a2976710b 473 SUPERFAMILY SSF52540 183 434 6.43E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01865 56aa13583ac113d2129f368a2976710b 473 Gene3D G3DSA:3.40.50.300 167 449 1.6E-101 T 12-10-2018 THERU_01865 56aa13583ac113d2129f368a2976710b 473 Pfam PF00772 DnaB-like helicase N terminal domain 12 96 6.8E-13 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THERU_06025 5db7327af2003c4dfc7da5d4769b395e 369 SUPERFAMILY SSF103473 15 369 2.75E-32 T 12-10-2018 IPR036259 MFS transporter superfamily THERU_06025 5db7327af2003c4dfc7da5d4769b395e 369 Pfam PF07690 Major Facilitator Superfamily 201 365 7.7E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THERU_06025 5db7327af2003c4dfc7da5d4769b395e 369 Gene3D G3DSA:1.20.1250.20 12 180 4.3E-9 T 12-10-2018 THERU_06025 5db7327af2003c4dfc7da5d4769b395e 369 Gene3D G3DSA:1.20.1250.20 181 369 1.0E-17 T 12-10-2018 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 Pfam PF00154 recA bacterial DNA recombination protein 14 274 6.6E-135 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 Gene3D G3DSA:3.40.50.300 34 274 7.9E-86 T 12-10-2018 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 Hamap MF_00268 Protein RecA [recA]. 12 336 50.466 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 SUPERFAMILY SSF54752 277 332 1.23E-19 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 SUPERFAMILY SSF52540 12 274 4.85E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 11 331 3.5E-166 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 ProSitePatterns PS00321 recA signature. 220 228 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 Gene3D G3DSA:3.30.250.10 275 333 1.1E-25 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 134 163 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 304 321 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 250 279 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 217 245 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 100 129 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 PRINTS PR00142 RecA protein signature 172 201 3.5E-82 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THERU_00565 af28b283eaa42eb3efd232dc3fd2bcc6 344 SMART SM00382 64 235 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07705 430ca8c11509411651a707822ca2ea8b 167 Pfam PF01782 RimM N-terminal domain 6 88 8.0E-11 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 THERU_07705 430ca8c11509411651a707822ca2ea8b 167 SUPERFAMILY SSF50447 3 92 6.0E-12 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07705 430ca8c11509411651a707822ca2ea8b 167 Gene3D G3DSA:2.40.30.60 3 92 4.8E-15 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 THERU_07705 430ca8c11509411651a707822ca2ea8b 167 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 166 17.127 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THERU_07705 430ca8c11509411651a707822ca2ea8b 167 SUPERFAMILY SSF50346 98 160 3.66E-11 T 12-10-2018 IPR011033 PRC-barrel-like superfamily THERU_07705 430ca8c11509411651a707822ca2ea8b 167 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 160 1.3E-31 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THERU_07705 430ca8c11509411651a707822ca2ea8b 167 Pfam PF05239 PRC-barrel domain 96 162 6.3E-6 T 12-10-2018 IPR027275 PRC-barrel domain THERU_07705 430ca8c11509411651a707822ca2ea8b 167 Gene3D G3DSA:2.30.30.240 94 165 9.5E-9 T 12-10-2018 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 Gene3D G3DSA:3.30.470.130 1 449 1.9E-194 T 12-10-2018 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 SUPERFAMILY SSF51246 330 447 2.2E-43 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 SMART SM00878 335 441 4.3E-62 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 7.4E-196 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 SUPERFAMILY SSF52440 1 112 1.8E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 Pfam PF02785 Biotin carboxylase C-terminal domain 335 442 2.8E-41 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.8E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 7.5E-79 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_03940 0b2f97444eb265403535f2ffe9e6facc 472 SUPERFAMILY SSF56059 82 347 2.19E-71 T 12-10-2018 THERU_00610 d7c954f0c214912cad72cbab6be19612 242 SMART SM00331 17 242 1.8E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THERU_00610 d7c954f0c214912cad72cbab6be19612 242 Gene3D G3DSA:3.60.40.10 1 242 1.3E-47 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THERU_00610 d7c954f0c214912cad72cbab6be19612 242 SMART SM00332 9 240 1.4E-16 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THERU_00610 d7c954f0c214912cad72cbab6be19612 242 SUPERFAMILY SSF81606 1 241 1.96E-44 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THERU_00610 d7c954f0c214912cad72cbab6be19612 242 Pfam PF13672 Protein phosphatase 2C 39 226 4.6E-11 T 12-10-2018 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 Gene3D G3DSA:3.40.50.740 107 195 8.4E-35 T 12-10-2018 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 SUPERFAMILY SSF53706 37 195 6.94E-53 T 12-10-2018 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 104 2.3E-19 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 4.6E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 SMART SM00926 43 104 3.1E-21 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02635 d4cacd2ad3aad1c093eb3ecc06fdea9c 195 Gene3D G3DSA:2.20.25.90 40 106 9.1E-18 T 12-10-2018 THERU_04235 17e3856dbae672c462b28d3168813423 245 SUPERFAMILY SSF63380 7 113 2.41E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THERU_04235 17e3856dbae672c462b28d3168813423 245 Pfam PF00970 Oxidoreductase FAD-binding domain 14 109 8.5E-18 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 Pfam PF00175 Oxidoreductase NAD-binding domain 121 225 3.4E-16 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00406 Cytochrome B5 reductase signature 120 139 5.0E-12 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00406 Cytochrome B5 reductase signature 212 220 5.0E-12 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00406 Cytochrome B5 reductase signature 97 111 5.0E-12 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00406 Cytochrome B5 reductase signature 60 67 5.0E-12 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00406 Cytochrome B5 reductase signature 158 169 5.0E-12 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THERU_04235 17e3856dbae672c462b28d3168813423 245 Gene3D G3DSA:3.40.50.80 114 245 2.3E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THERU_04235 17e3856dbae672c462b28d3168813423 245 SUPERFAMILY SSF52343 102 242 6.55E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THERU_04235 17e3856dbae672c462b28d3168813423 245 Gene3D G3DSA:2.40.30.10 6 109 2.5E-25 T 12-10-2018 THERU_04235 17e3856dbae672c462b28d3168813423 245 PIRSF PIRSF006816 8 244 4.9E-28 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 220 1.2E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 60 67 1.2E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 120 139 1.2E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THERU_04235 17e3856dbae672c462b28d3168813423 245 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 158 169 1.2E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 1134 14.976 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 SUPERFAMILY SSF50677 189 340 1.44E-62 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Pfam PF08264 Anticodon-binding domain of tRNA 854 1014 1.7E-38 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:1.10.730.10 815 1005 2.6E-52 T 12-10-2018 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 SUPERFAMILY SSF46589 1070 1133 3.87E-7 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:3.40.50.620 651 810 2.3E-48 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 SUPERFAMILY SSF52374 13 819 4.78E-99 T 12-10-2018 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:3.90.740.10 197 336 1.1E-56 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 SUPERFAMILY SSF47323 823 1082 2.24E-57 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:3.40.50.620 506 614 1.2E-22 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 PRINTS PR00986 Valyl-tRNA synthetase signature 693 714 2.7E-36 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 PRINTS PR00986 Valyl-tRNA synthetase signature 344 357 2.7E-36 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 PRINTS PR00986 Valyl-tRNA synthetase signature 723 741 2.7E-36 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 PRINTS PR00986 Valyl-tRNA synthetase signature 229 246 2.7E-36 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 2.7E-36 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 1070 1133 9.9E-7 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:1.10.287.380 1063 1133 8.8E-8 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 521 578 1.2E-15 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 375 7.3E-127 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 678 811 4.7E-52 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04120 55e85a64221e23156b79f0d666ce3266 1140 Gene3D G3DSA:3.40.50.620 4 196 5.3E-64 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_08170 14fdcb55b86c7319812552ea01db508d 283 Pfam PF07549 SecD/SecF GG Motif 28 50 7.2E-10 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THERU_08170 14fdcb55b86c7319812552ea01db508d 283 Gene3D G3DSA:1.20.1640.10 95 281 2.1E-8 T 12-10-2018 THERU_08170 14fdcb55b86c7319812552ea01db508d 283 SUPERFAMILY SSF82866 106 277 2.62E-32 T 12-10-2018 THERU_08170 14fdcb55b86c7319812552ea01db508d 283 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 29 266 1.9E-70 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THERU_08170 14fdcb55b86c7319812552ea01db508d 283 PRINTS PR01755 Bacterial translocase SecF protein signature 28 43 6.4E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_08170 14fdcb55b86c7319812552ea01db508d 283 PRINTS PR01755 Bacterial translocase SecF protein signature 134 148 6.4E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_08170 14fdcb55b86c7319812552ea01db508d 283 PRINTS PR01755 Bacterial translocase SecF protein signature 214 229 6.4E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_08170 14fdcb55b86c7319812552ea01db508d 283 PRINTS PR01755 Bacterial translocase SecF protein signature 182 200 6.4E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_08170 14fdcb55b86c7319812552ea01db508d 283 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 101 263 5.2E-49 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_08170 14fdcb55b86c7319812552ea01db508d 283 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 1 277 27.076 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THERU_08170 14fdcb55b86c7319812552ea01db508d 283 Pfam PF02355 Protein export membrane protein 95 274 1.3E-62 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 220 400 2.6E-68 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 SUPERFAMILY SSF52374 4 571 5.36E-145 T 12-10-2018 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 414 569 1.5E-10 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 169 1.1E-27 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 SUPERFAMILY SSF50677 225 411 1.15E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 Gene3D G3DSA:3.40.50.620 32 570 2.2E-274 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 570 6.8E-272 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 Gene3D G3DSA:3.90.740.10 227 412 2.2E-274 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 214 233 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 523 545 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 484 502 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 125 142 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 183 196 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 151 167 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 PRINTS PR00985 Leucyl-tRNA synthetase signature 556 566 7.0E-55 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THERU_05945 b20fd74173fd5b4797322d069ad7eb7c 602 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 SMART SM00420 3 54 1.3E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 Pfam PF08220 DeoR-like helix-turn-helix domain 3 53 1.5E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 SUPERFAMILY SSF160387 83 181 2.88E-26 T 12-10-2018 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 SUPERFAMILY SSF46785 2 51 3.58E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 Gene3D G3DSA:1.10.10.10 1 51 1.5E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 20 34 4.0E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 34 52 4.0E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THERU_04600 7298749d23aff121963cdb13b8e0dd30 190 Pfam PF05573 NosL 121 169 2.1E-7 T 12-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 SMART SM00478 57 219 4.6E-10 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 Gene3D G3DSA:1.10.340.30 30 159 5.8E-57 T 12-10-2018 THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 Gene3D G3DSA:1.10.1670.10 9 221 5.8E-57 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 16 224 29.04 T 12-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 PIRSF PIRSF005954 6 224 4.9E-72 T 12-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 THERU_06385 7761d4e2a2d27bbe1eb38b87742caed5 224 SUPERFAMILY SSF48150 37 194 6.95E-17 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 Gene3D G3DSA:3.40.1010.10 1 117 2.7E-45 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 SUPERFAMILY SSF53790 1 238 3.53E-76 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 2.2E-49 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 Gene3D G3DSA:3.30.950.10 118 247 4.4E-37 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 THERU_04680 1e0fd2985d5a47c27ab8f719c890e52d 249 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 236 3.5E-91 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 161 179 3.7E-33 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 444 458 3.7E-33 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 273 282 3.7E-33 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 343 359 3.7E-33 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 74 87 3.7E-33 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Gene3D G3DSA:2.70.20.10 183 427 5.2E-120 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 4 526 3.2E-155 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 SUPERFAMILY SSF56712 1 526 1.7E-158 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Gene3D G3DSA:1.10.290.10 239 357 5.2E-120 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 268 282 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Pfam PF01131 DNA topoisomerase 126 518 6.7E-121 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Gene3D G3DSA:1.10.460.10 134 524 5.2E-120 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Gene3D G3DSA:3.40.50.140 1 132 6.0E-38 T 12-10-2018 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 536 40.844 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 SMART SM00436 102 191 1.5E-41 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 Pfam PF01751 Toprim domain 3 111 4.8E-21 T 12-10-2018 IPR006171 TOPRIM domain THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 SMART SM00493 1 100 1.4E-24 T 12-10-2018 IPR006171 TOPRIM domain THERU_07425 b3ff462aca4a90ffa7d0d6b3ddedfd18 536 SMART SM00437 231 481 9.1E-89 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 Gene3D G3DSA:3.30.470.130 1 444 1.5E-184 T 12-10-2018 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 SUPERFAMILY SSF56059 83 333 2.12E-67 T 12-10-2018 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 Pfam PF02785 Biotin carboxylase C-terminal domain 333 441 1.3E-37 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 SUPERFAMILY SSF51246 328 442 4.03E-40 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.3E-44 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 7.0E-81 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 1.5E-200 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 SMART SM00878 333 440 3.4E-60 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_02815 fe1b1f3be53896d24c870a3c6a25fafb 444 SUPERFAMILY SSF52440 1 112 2.16E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 SUPERFAMILY SSF55120 3 219 1.27E-75 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 284 16.846 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 SUPERFAMILY SSF88697 230 285 2.73E-5 T 12-10-2018 IPR015947 PUA-like superfamily THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 231 283 5.2E-9 T 12-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 172 223 3.1E-13 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 Gene3D G3DSA:3.30.2350.10 1 226 8.3E-84 T 12-10-2018 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 171 9.9E-49 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 THERU_07965 1bd9fa2145ae0988cb1b4e9de31e9b16 287 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 4 210 4.8E-69 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_02090 e54e881b5570d7f8c23949f7b1ec9374 580 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 215 271 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02090 e54e881b5570d7f8c23949f7b1ec9374 580 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 15 475 3.9E-82 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02090 e54e881b5570d7f8c23949f7b1ec9374 580 SUPERFAMILY SSF81442 10 545 9.29E-94 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02090 e54e881b5570d7f8c23949f7b1ec9374 580 Gene3D G3DSA:1.20.210.10 3 554 1.6E-116 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 SMART SM00267 532 704 1.4E-44 T 12-10-2018 IPR000160 GGDEF domain THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 Pfam PF00563 EAL domain 719 950 1.5E-60 T 12-10-2018 IPR001633 EAL domain THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 542 700 8.0E-45 T 12-10-2018 IPR000160 GGDEF domain THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 SUPERFAMILY SSF55073 548 701 1.73E-43 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 Gene3D G3DSA:3.30.70.270 538 710 6.3E-51 T 12-10-2018 THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 Gene3D G3DSA:3.20.20.450 713 962 1.3E-72 T 12-10-2018 IPR035919 EAL domain superfamily THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 Pfam PF00990 Diguanylate cyclase, GGDEF domain 544 698 1.8E-40 T 12-10-2018 IPR000160 GGDEF domain THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 SUPERFAMILY SSF141868 719 960 2.35E-66 T 12-10-2018 IPR035919 EAL domain superfamily THERU_01390 d2aeec629266210e4b64ba8bbceb08dd 964 SMART SM00052 713 955 1.1E-54 T 12-10-2018 IPR001633 EAL domain THERU_02355 7863a03108583969b4e662b221ad9c56 109 SUPERFAMILY SSF46785 6 81 1.49E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_02355 7863a03108583969b4e662b221ad9c56 109 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 3.0E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_02355 7863a03108583969b4e662b221ad9c56 109 Gene3D G3DSA:1.10.10.10 1 100 8.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_02355 7863a03108583969b4e662b221ad9c56 109 SMART SM00418 12 93 3.7E-29 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_02355 7863a03108583969b4e662b221ad9c56 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 6.2E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_02355 7863a03108583969b4e662b221ad9c56 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 6.2E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_02355 7863a03108583969b4e662b221ad9c56 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 6.2E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_02355 7863a03108583969b4e662b221ad9c56 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 6.2E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 SUPERFAMILY SSF53686 28 428 2.49E-116 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THERU_05090 e955ae58cf01d14bc35565bfac304445 436 Gene3D G3DSA:3.40.50.1100 14 422 8.8E-180 T 12-10-2018 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 Gene3D G3DSA:3.40.50.1100 15 239 8.8E-180 T 12-10-2018 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 PIRSF PIRSF001413 10 435 2.5E-129 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 77 416 4.0E-44 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THERU_05090 e955ae58cf01d14bc35565bfac304445 436 PIRSF PIRSF500824 2 436 2.1E-211 T 12-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 106 120 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 22 429 42.173 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05090 e955ae58cf01d14bc35565bfac304445 436 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 14 431 2.9E-219 T 12-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 137 2.5E-25 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 Gene3D G3DSA:3.40.50.2000 159 333 8.0E-90 T 12-10-2018 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 SUPERFAMILY SSF53756 2 345 3.66E-83 T 12-10-2018 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 2 349 29.128 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 325 2.4E-34 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 342 2.3E-81 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_06335 99052e2c9934f0b36d133c3dff105d48 352 Gene3D G3DSA:3.40.50.2000 4 158 8.0E-90 T 12-10-2018 THERU_00790 d00ca03519742ec2c51fb7a1120264bd 226 Gene3D G3DSA:3.40.140.10 101 226 4.2E-40 T 12-10-2018 THERU_00790 d00ca03519742ec2c51fb7a1120264bd 226 Pfam PF04002 RadC-like JAB domain 104 224 1.2E-37 T 12-10-2018 IPR025657 RadC-like JAB domain THERU_00790 d00ca03519742ec2c51fb7a1120264bd 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 226 1.6E-67 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 THERU_00790 d00ca03519742ec2c51fb7a1120264bd 226 SUPERFAMILY SSF48150 32 101 6.67E-5 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THERU_07920 4bd279a933908593a16cc86ba0140893 460 SMART SM00849 13 238 5.1E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_07920 4bd279a933908593a16cc86ba0140893 460 Gene3D G3DSA:3.60.15.10 6 435 3.1E-147 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_07920 4bd279a933908593a16cc86ba0140893 460 Pfam PF00753 Metallo-beta-lactamase superfamily 12 245 7.2E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_07920 4bd279a933908593a16cc86ba0140893 460 Gene3D G3DSA:3.40.50.10890 220 402 3.1E-147 T 12-10-2018 THERU_07920 4bd279a933908593a16cc86ba0140893 460 SMART SM01027 252 376 1.7E-56 T 12-10-2018 IPR022712 Beta-Casp domain THERU_07920 4bd279a933908593a16cc86ba0140893 460 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 390 452 7.1E-16 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain THERU_07920 4bd279a933908593a16cc86ba0140893 460 Pfam PF10996 Beta-Casp domain 252 376 4.7E-25 T 12-10-2018 IPR022712 Beta-Casp domain THERU_07920 4bd279a933908593a16cc86ba0140893 460 SUPERFAMILY SSF56281 1 460 4.72E-132 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 SUPERFAMILY SSF47928 17 101 3.01E-7 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 PRINTS PR00125 ATP synthase delta subunit signature 152 170 5.1E-7 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 PRINTS PR00125 ATP synthase delta subunit signature 76 87 5.1E-7 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 PRINTS PR00125 ATP synthase delta subunit signature 137 152 5.1E-7 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 Pfam PF00213 ATP synthase delta (OSCP) subunit 10 173 4.0E-27 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 10 173 1.9E-21 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03665 110d0c7b2236d6b688b6007faa5258cb 174 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 174 12.162 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 485 36.286 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 SUPERFAMILY SSF52949 1 168 1.0E-19 T 12-10-2018 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 331 338 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 170 476 5.4E-121 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 Gene3D G3DSA:3.40.220.10 2 153 5.0E-21 T 12-10-2018 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 Gene3D G3DSA:3.40.630.10 154 485 1.2E-135 T 12-10-2018 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 33 138 3.6E-17 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 PRINTS PR00481 Cytosol aminopeptidase signature 305 326 6.4E-53 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 PRINTS PR00481 Cytosol aminopeptidase signature 268 289 6.4E-53 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 PRINTS PR00481 Cytosol aminopeptidase signature 246 263 6.4E-53 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 PRINTS PR00481 Cytosol aminopeptidase signature 355 370 6.4E-53 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 PRINTS PR00481 Cytosol aminopeptidase signature 327 347 6.4E-53 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THERU_00130 6aa25a2c68edaa77af21bfe4a624ed7b 485 SUPERFAMILY SSF53187 165 482 9.58E-118 T 12-10-2018 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 446 31.834 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Gene3D G3DSA:1.20.120.430 123 446 8.7E-102 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Gene3D G3DSA:3.40.50.300 218 374 8.7E-102 T 12-10-2018 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Pfam PF01926 50S ribosome-binding GTPase 220 332 8.6E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Gene3D G3DSA:3.30.1360.120 1 122 6.9E-41 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 121 5.0E-35 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 446 6.5E-119 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 SUPERFAMILY SSF52540 74 366 1.43E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 362 2.5E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_00380 995338404ee1e54ddae9dfb39eaad4b4 446 Pfam PF12631 MnmE helical domain 124 443 3.6E-51 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 THERU_01565 11ee0dac48841b225b573ac6f00397dd 571 Gene3D G3DSA:3.60.15.10 261 476 4.1E-15 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 SUPERFAMILY SSF52029 184 376 8.22E-85 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 527 3.8E-101 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 531 3.2E-262 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 Gene3D G3DSA:3.50.7.10 192 372 1.4E-242 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 SUPERFAMILY SSF48592 3 230 9.03E-67 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 SUPERFAMILY SSF48592 373 529 2.75E-36 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.413 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 PRINTS PR00298 60kDa chaperonin signature 83 110 1.5E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 PRINTS PR00298 60kDa chaperonin signature 268 291 1.5E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 PRINTS PR00298 60kDa chaperonin signature 27 53 1.5E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 PRINTS PR00298 60kDa chaperonin signature 398 419 1.5E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 PRINTS PR00298 60kDa chaperonin signature 350 375 1.5E-71 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 Gene3D G3DSA:1.10.560.10 8 525 1.4E-242 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily THERU_06905 e792cafa89c9048c96cbc45a35e3bd28 546 Gene3D G3DSA:3.30.260.10 136 410 1.4E-242 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 Pfam PF16199 Radical_SAM C-terminal domain 213 298 1.3E-25 T 12-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 SUPERFAMILY SSF102114 7 301 3.53E-46 T 12-10-2018 THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 Pfam PF04055 Radical SAM superfamily 44 207 1.4E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 8 307 1.6E-125 T 12-10-2018 IPR005911 Protein YhcC-like GO:0051536 THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 Gene3D G3DSA:3.80.30.20 43 255 3.5E-17 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_03420 0d7d39941f4b683c64686cd1e550d211 312 SMART SM00729 24 252 1.0E-41 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 SUPERFAMILY SSF56059 128 400 3.36E-112 T 12-10-2018 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 SMART SM01096 421 541 2.8E-69 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 SUPERFAMILY SSF52440 1 127 9.5E-50 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 7.4E-76 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 SUPERFAMILY SSF48108 396 543 3.01E-50 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 Gene3D G3DSA:1.10.1030.10 407 544 3.5E-48 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 Gene3D G3DSA:3.40.50.20 1 116 1.9E-48 T 12-10-2018 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 Gene3D G3DSA:3.30.470.20 120 402 2.7E-128 T 12-10-2018 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 541 5.5E-42 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_00970 9bcf949802bc6ee9af9dce1fa29c0116 557 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 7.2E-67 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06315 153435bcd6dee280fb870194ffe6b8b0 88 Gene3D G3DSA:2.60.120.10 5 87 9.6E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold THERU_06315 153435bcd6dee280fb870194ffe6b8b0 88 SUPERFAMILY SSF51182 21 79 1.4E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily THERU_06315 153435bcd6dee280fb870194ffe6b8b0 88 Pfam PF07883 Cupin domain 23 77 7.7E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Gene3D G3DSA:1.10.10.60 472 513 4.0E-16 T 12-10-2018 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Gene3D G3DSA:3.40.50.300 216 394 3.5E-69 T 12-10-2018 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SUPERFAMILY SSF55785 96 162 3.14E-7 T 12-10-2018 IPR035965 PAS domain superfamily THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Pfam PF13188 PAS domain 11 35 0.003 T 12-10-2018 IPR000014 PAS domain THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Pfam PF13188 PAS domain 115 160 0.02 T 12-10-2018 IPR000014 PAS domain THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 247 260 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Gene3D G3DSA:3.30.450.20 104 215 5.5E-10 T 12-10-2018 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SUPERFAMILY SSF52540 223 464 2.31E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 309 324 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Gene3D G3DSA:1.10.8.60 396 466 1.4E-28 T 12-10-2018 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 477 494 1.4E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 494 514 1.4E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Gene3D G3DSA:3.30.450.20 4 102 2.3E-6 T 12-10-2018 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SUPERFAMILY SSF46689 468 514 1.58E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SMART SM00382 243 386 2.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Pfam PF00158 Sigma-54 interaction domain 223 389 2.6E-68 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SMART SM00091 112 179 0.028 T 12-10-2018 IPR000014 PAS domain THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 SMART SM00091 1 67 52.0 T 12-10-2018 IPR000014 PAS domain THERU_05850 b237c2ed96dfb9649a3ad3a7f20a5ad5 517 Pfam PF02954 Bacterial regulatory protein, Fis family 472 511 1.1E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 SUPERFAMILY SSF111369 57 295 1.2E-25 T 12-10-2018 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 367 5.1E-64 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 Gene3D G3DSA:2.40.50.100 68 221 1.4E-69 T 12-10-2018 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 280 3.5E-18 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 Gene3D G3DSA:1.10.287.470 102 184 1.4E-69 T 12-10-2018 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 Gene3D G3DSA:2.40.30.170 55 295 1.4E-69 T 12-10-2018 THERU_07845 a42cc603bc6ef0df6de561a03a6488f0 369 Gene3D G3DSA:2.40.420.20 296 354 1.4E-69 T 12-10-2018 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 169 2.2E-26 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 4 282 5.2E-72 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 Gene3D G3DSA:3.30.300.20 186 301 6.8E-38 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 Pfam PF01926 50S ribosome-binding GTPase 6 124 5.6E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 Hamap MF_00367 GTPase Era [era]. 1 299 34.93 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 Pfam PF07650 KH domain 209 288 2.6E-14 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 SUPERFAMILY SSF54814 182 300 3.6E-34 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 Gene3D G3DSA:3.40.50.300 1 185 1.3E-51 T 12-10-2018 THERU_08445 bbc94cd78abea098d609d93c295dabf4 302 SUPERFAMILY SSF52540 6 205 2.07E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 Gene3D G3DSA:3.10.310.10 3 270 2.1E-84 T 12-10-2018 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 Pfam PF01678 Diaminopimelate epimerase 148 258 3.0E-22 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 Pfam PF01678 Diaminopimelate epimerase 3 129 1.8E-31 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 272 8.3E-87 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 Gene3D G3DSA:3.10.310.10 123 261 2.1E-84 T 12-10-2018 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 SUPERFAMILY SSF54506 137 272 1.14E-36 T 12-10-2018 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 SUPERFAMILY SSF54506 1 131 1.17E-36 T 12-10-2018 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 274 33.942 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THERU_02765 e9e17c8b62a09b5f432c4a40ecf6091f 279 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 72 86 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THERU_02855 ad829bb88005781a2abf86b51435b17e 279 Gene3D G3DSA:3.30.160.60 249 279 2.0E-10 T 12-10-2018 THERU_02855 ad829bb88005781a2abf86b51435b17e 279 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 1 277 8.2E-65 T 12-10-2018 IPR003770 Endolytic murein transglycosylase THERU_02855 ad829bb88005781a2abf86b51435b17e 279 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 1 279 29.745 T 12-10-2018 IPR003770 Endolytic murein transglycosylase THERU_02855 ad829bb88005781a2abf86b51435b17e 279 Pfam PF02618 YceG-like family 2 275 1.5E-75 T 12-10-2018 IPR003770 Endolytic murein transglycosylase THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF54791 549 625 1.05E-11 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Gene3D G3DSA:2.40.50.140 619 690 4.0E-20 T 12-10-2018 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF01138 3' exoribonuclease family, domain 1 320 453 1.6E-22 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 2.8E-18 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF46915 238 316 1.78E-11 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 PIRSF PIRSF005499 1 692 1.3E-283 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF00575 S1 RNA binding domain 616 684 1.1E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SMART SM00322 549 614 2.1E-6 T 12-10-2018 IPR004087 K Homology domain GO:0003676 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF50249 606 684 3.0E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF54211 293 485 5.06E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 1.1E-14 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF03725 3' exoribonuclease family, domain 2 458 525 1.7E-4 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Gene3D G3DSA:3.30.230.70 1 226 2.7E-75 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF55666 447 546 9.26E-29 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 689 28.048 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF54211 10 142 8.6E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Gene3D G3DSA:3.30.1370.10 547 618 9.9E-15 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SMART SM00316 617 686 8.1E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 244 315 1.0E-11 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Pfam PF00013 KH domain 554 610 7.5E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 Gene3D G3DSA:3.30.230.70 234 546 7.1E-111 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 SUPERFAMILY SSF55666 136 228 5.11E-22 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_01370 5ab4bda6fa33760a4e8992aba3d8f6c9 692 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 684 5.1E-272 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THERU_04295 3c5efdceea58be4be2cd0738eb8ba6c1 276 Pfam PF13393 Histidyl-tRNA synthetase 29 270 2.4E-37 T 12-10-2018 THERU_04295 3c5efdceea58be4be2cd0738eb8ba6c1 276 Gene3D G3DSA:3.30.930.10 29 272 4.1E-45 T 12-10-2018 THERU_04295 3c5efdceea58be4be2cd0738eb8ba6c1 276 SUPERFAMILY SSF55681 29 273 2.02E-32 T 12-10-2018 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 Gene3D G3DSA:4.10.520.10 1 90 4.8E-34 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 SUPERFAMILY SSF47729 1 90 8.83E-32 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 SMART SM00411 1 90 2.3E-39 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 8.6E-14 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 8.6E-14 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 8.6E-14 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THERU_00445 12058fb4c5fc7a3018d17879de3d54a2 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.8E-33 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 PRINTS PR00046 Major sigma-70 factor signature 544 555 2.9E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 PRINTS PR00046 Major sigma-70 factor signature 360 373 2.9E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 PRINTS PR00046 Major sigma-70 factor signature 384 392 2.9E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 PRINTS PR00046 Major sigma-70 factor signature 508 520 2.9E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 PRINTS PR00046 Major sigma-70 factor signature 529 544 2.9E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Pfam PF00140 Sigma-70 factor, region 1.2 82 114 9.7E-16 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Gene3D G3DSA:1.10.601.10 80 408 1.4E-93 T 12-10-2018 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 529 555 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Pfam PF04539 Sigma-70 region 3 415 491 1.8E-26 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Gene3D G3DSA:1.10.220.120 3 61 6.8E-12 T 12-10-2018 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Pfam PF03979 Sigma-70 factor, region 1.1 5 63 2.8E-12 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 SUPERFAMILY SSF88659 409 482 1.0E-20 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 SUPERFAMILY SSF88659 466 565 2.99E-29 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 SUPERFAMILY SSF88946 99 403 4.55E-62 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Gene3D G3DSA:1.10.10.10 490 570 3.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Pfam PF04542 Sigma-70 region 2 336 405 7.3E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 569 34.259 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Pfam PF04545 Sigma-70, region 4 504 557 7.1E-19 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 332 567 4.6E-118 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 335 557 3.6E-41 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 360 373 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_01240 d6b78d0e1370c0df0a5a8b6379a19ead 570 Gene3D G3DSA:1.10.10.10 409 485 3.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_07535 ce163a9c52fb37788f6a40e22f91d743 392 Gene3D G3DSA:1.20.1250.20 3 193 9.7E-14 T 12-10-2018 THERU_07535 ce163a9c52fb37788f6a40e22f91d743 392 SUPERFAMILY SSF103473 9 374 1.96E-34 T 12-10-2018 IPR036259 MFS transporter superfamily THERU_07535 ce163a9c52fb37788f6a40e22f91d743 392 Gene3D G3DSA:1.20.1250.20 206 382 4.3E-11 T 12-10-2018 THERU_07535 ce163a9c52fb37788f6a40e22f91d743 392 Pfam PF07690 Major Facilitator Superfamily 15 248 2.0E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 518 8.9E-26 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 596 8.9E-26 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 394 408 8.9E-26 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 246 260 8.9E-26 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 580 8.9E-26 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Gene3D G3DSA:3.30.70.100 1 74 7.2E-21 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00943 Copper-transporting ATPase signature 538 555 2.5E-5 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00943 Copper-transporting ATPase signature 46 66 2.5E-5 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 PRINTS PR00943 Copper-transporting ATPase signature 319 333 2.5E-5 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 SUPERFAMILY SSF81653 200 296 8.5E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Pfam PF00403 Heavy-metal-associated domain 5 65 1.0E-14 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Pfam PF00122 E1-E2 ATPase 198 373 1.1E-50 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 477 639 4.5E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 417 6.2E-43 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 116 666 3.4E-146 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Gene3D G3DSA:3.40.50.1000 376 596 6.3E-62 T 12-10-2018 IPR023214 HAD superfamily THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Gene3D G3DSA:2.70.150.20 189 300 4.7E-25 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 SUPERFAMILY SSF56784 393 665 1.48E-43 T 12-10-2018 IPR036412 HAD-like superfamily THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 SUPERFAMILY SSF55008 1 69 1.05E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 134 666 7.1E-137 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Gene3D G3DSA:3.40.1110.10 404 493 6.3E-62 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 396 402 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 165 666 2.2E-95 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 Pfam PF00702 haloacid dehalogenase-like hydrolase 391 575 4.3E-38 T 12-10-2018 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 SUPERFAMILY SSF81665 167 631 1.7E-14 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THERU_06285 baf6f20f22926d7ccb6a5fe1ad55a105 667 ProSitePatterns PS01229 Hypothetical cof family signature 2. 561 583 - T 12-10-2018 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 466 2.7E-160 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Gene3D G3DSA:2.170.220.10 114 226 1.3E-153 T 12-10-2018 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Pfam PF08264 Anticodon-binding domain of tRNA 370 456 1.1E-6 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 2 129 8.0E-13 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 486 46.088 T 12-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 SUPERFAMILY SSF47323 342 482 9.91E-30 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Gene3D G3DSA:1.10.730.10 330 486 1.6E-34 T 12-10-2018 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Gene3D G3DSA:3.40.50.620 3 327 1.3E-153 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 85 96 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 223 234 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 249 264 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 PRINTS PR01041 Methionyl-tRNA synthetase signature 341 352 1.3E-36 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 SUPERFAMILY SSF52374 2 337 1.82E-114 T 12-10-2018 THERU_01065 cdc712b8ec4df72feee2192942d96459 487 Pfam PF09334 tRNA synthetases class I (M) 141 354 5.0E-59 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01780 babc6f3ef0469875e23ffa817c10a317 154 Gene3D G3DSA:3.40.50.960 1 154 2.3E-58 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_01780 babc6f3ef0469875e23ffa817c10a317 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 1.1E-50 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_01780 babc6f3ef0469875e23ffa817c10a317 154 SUPERFAMILY SSF52121 4 153 1.1E-56 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_01780 babc6f3ef0469875e23ffa817c10a317 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 29.083 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_01780 babc6f3ef0469875e23ffa817c10a317 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 1.7E-53 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 Pfam PF02222 ATP-grasp domain 100 265 1.4E-48 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type THERU_07400 8e69f86934f3cbb40e50419449436da0 360 SUPERFAMILY SSF51246 290 356 9.42E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 SUPERFAMILY SSF52440 2 77 2.16E-18 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_07400 8e69f86934f3cbb40e50419449436da0 360 Gene3D G3DSA:3.30.1490.20 91 169 5.7E-22 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 345 7.0E-120 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 SUPERFAMILY SSF56059 92 286 1.66E-48 T 12-10-2018 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 Gene3D G3DSA:3.30.470.20 170 358 2.5E-65 T 12-10-2018 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 340 35.93 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THERU_07400 8e69f86934f3cbb40e50419449436da0 360 Gene3D G3DSA:3.40.50.20 1 90 5.4E-27 T 12-10-2018 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 SUPERFAMILY SSF47323 647 919 5.98E-65 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 225 248 7.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 387 402 7.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 524 537 7.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 556 565 7.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 48 59 7.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 55 66 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 SUPERFAMILY SSF50677 204 389 1.36E-54 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 835 1.8E-284 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Gene3D G3DSA:3.40.50.620 24 624 2.1E-246 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Pfam PF08264 Anticodon-binding domain of tRNA 679 837 1.4E-26 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Gene3D G3DSA:3.90.740.10 195 394 2.1E-246 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 636 2.3E-206 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 SUPERFAMILY SSF52374 1 641 6.81E-147 T 12-10-2018 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Gene3D G3DSA:1.10.730.20 635 921 5.0E-84 T 12-10-2018 THERU_02975 a083d43d1d397058298f011f9320a9e9 922 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 918 20.501 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 THERU_00365 eb0768a99f02265f0830fd5f1c63da9d 133 SMART SM00422 9 78 9.4E-26 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THERU_00365 eb0768a99f02265f0830fd5f1c63da9d 133 Pfam PF13411 MerR HTH family regulatory protein 9 76 8.2E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THERU_00365 eb0768a99f02265f0830fd5f1c63da9d 133 SUPERFAMILY SSF46955 9 96 1.88E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily THERU_00365 eb0768a99f02265f0830fd5f1c63da9d 133 Gene3D G3DSA:1.10.1660.10 2 99 3.4E-26 T 12-10-2018 THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 246 370 1.5E-17 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 247 2.0E-12 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SUPERFAMILY SSF55785 131 243 1.44E-19 T 12-10-2018 IPR035965 PAS domain superfamily THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Gene3D G3DSA:3.30.70.270 362 529 1.3E-49 T 12-10-2018 THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Pfam PF08447 PAS fold 151 237 9.3E-22 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Pfam PF13426 PAS domain 259 361 5.3E-12 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Gene3D G3DSA:3.30.450.20 245 361 4.7E-18 T 12-10-2018 THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SUPERFAMILY SSF55785 245 361 1.3E-18 T 12-10-2018 IPR035965 PAS domain superfamily THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00086 202 244 3.1E-4 T 12-10-2018 IPR001610 PAC motif THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00086 323 363 93.0 T 12-10-2018 IPR001610 PAC motif THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SUPERFAMILY SSF55785 5 97 2.44E-6 T 12-10-2018 IPR035965 PAS domain superfamily THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 525 1.3E-42 T 12-10-2018 IPR000160 GGDEF domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 528 4.2E-45 T 12-10-2018 IPR000160 GGDEF domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00267 363 529 4.7E-55 T 12-10-2018 IPR000160 GGDEF domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Gene3D G3DSA:3.30.450.20 138 244 3.6E-21 T 12-10-2018 THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 Pfam PF13188 PAS domain 8 57 0.023 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00091 5 75 12.0 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00091 124 194 8.7E-4 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SMART SM00091 249 316 9.9E-11 T 12-10-2018 IPR000014 PAS domain THERU_05675 f255aebd2cc3eb5405ce3ca994479def 529 SUPERFAMILY SSF55073 379 528 1.33E-42 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 9 16 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 Gene3D G3DSA:3.40.440.10 4 251 2.8E-90 T 12-10-2018 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 SMART SM00788 2 419 5.7E-236 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 Gene3D G3DSA:1.10.300.10 100 197 2.8E-90 T 12-10-2018 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 128 139 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 171.873 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 SUPERFAMILY SSF52540 2 422 6.59E-155 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 Gene3D G3DSA:3.90.170.10 262 426 8.8E-67 T 12-10-2018 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 Pfam PF00709 Adenylosuccinate synthetase 4 418 1.9E-163 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_03330 0717c1e9e1b64a25223d1de38d562902 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 4 423 1.6E-154 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 SMART SM00382 29 214 2.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 1.2E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 SUPERFAMILY SSF52540 5 236 2.13E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 Gene3D G3DSA:3.40.50.300 3 241 2.0E-71 T 12-10-2018 THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 241 1.5E-94 T 12-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 THERU_07420 ac09b575fbddf4d3539a65e81fc136be 241 Pfam PF00005 ABC transporter 20 166 1.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 Pfam PF00285 Citrate synthase, C-terminal domain 48 228 1.0E-38 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 Pfam PF00285 Citrate synthase, C-terminal domain 7 52 3.1E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 PRINTS PR00143 Citrate synthase signature 185 201 1.0E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 PRINTS PR00143 Citrate synthase signature 205 219 1.0E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 PRINTS PR00143 Citrate synthase signature 129 149 1.0E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 SUPERFAMILY SSF48256 5 229 3.4E-62 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 Gene3D G3DSA:1.10.230.10 101 199 1.4E-17 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain THERU_02245 a1f239a04e64f0d98c0d28632d61fb81 259 Gene3D G3DSA:1.10.580.10 3 55 1.2E-6 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 14 291 2.5E-134 T 12-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 Gene3D G3DSA:3.30.70.20 30 231 4.2E-85 T 12-10-2018 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 PIRSF PIRSF036298 7 295 2.4E-120 T 12-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 138 149 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 Pfam PF13247 4Fe-4S dicluster domain 97 193 1.0E-24 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 Pfam PF09163 Formate dehydrogenase N, transmembrane 249 291 9.3E-14 T 12-10-2018 IPR015246 Formate dehydrogenase, transmembrane THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 Gene3D G3DSA:3.30.70.20 25 166 4.2E-85 T 12-10-2018 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 SUPERFAMILY SSF54862 30 244 3.66E-63 T 12-10-2018 THERU_02625 44f71c0b7945a2b8ab695f842a6894fc 295 SUPERFAMILY SSF81597 249 291 6.8E-9 T 12-10-2018 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 PRINTS PR00956 Flagellar motor switch protein FliN signature 66 82 1.0E-22 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 65 1.0E-22 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 PRINTS PR00956 Flagellar motor switch protein FliN signature 95 110 1.0E-22 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 PRINTS PR00956 Flagellar motor switch protein FliN signature 82 95 1.0E-22 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 Gene3D G3DSA:2.30.330.10 36 128 7.3E-31 T 12-10-2018 IPR036429 SpoA-like superfamily THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 SUPERFAMILY SSF101801 47 126 7.72E-24 T 12-10-2018 IPR036429 SpoA-like superfamily THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 47 121 2.8E-28 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 THERU_00100 c86af0c4e305ba4ae18b46de1e7245ed 129 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 50 119 5.3E-25 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) THERU_02790 04e742fc702111a9703177353de93562 148 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 142 34.564 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THERU_02790 04e742fc702111a9703177353de93562 148 SUPERFAMILY SSF54637 1 137 2.43E-45 T 12-10-2018 IPR029069 HotDog domain superfamily THERU_02790 04e742fc702111a9703177353de93562 148 Pfam PF07977 FabA-like domain 10 134 2.8E-34 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THERU_02790 04e742fc702111a9703177353de93562 148 Gene3D G3DSA:3.10.129.10 1 146 6.3E-56 T 12-10-2018 THERU_02790 04e742fc702111a9703177353de93562 148 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 138 1.3E-60 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:1.10.8.60 892 983 1.9E-31 T 12-10-2018 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:1.10.1780.10 5 126 4.0E-10 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 750 768 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 765 783 1.1E-40 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 827 841 1.1E-40 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 794 812 1.1E-40 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 738 1.1E-40 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SMART SM00382 330 474 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SMART SM00382 716 870 3.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SUPERFAMILY SSF52540 292 648 3.06E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 335 447 1.3E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:1.10.1780.10 181 290 5.3E-5 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:3.40.50.300 291 478 5.6E-74 T 12-10-2018 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:3.40.50.300 669 890 9.9E-90 T 12-10-2018 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SUPERFAMILY SSF52540 665 981 4.65E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Pfam PF07724 AAA domain (Cdc48 subfamily) 715 886 2.7E-54 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Gene3D G3DSA:3.40.50.300 479 663 7.8E-45 T 12-10-2018 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 892 972 6.5E-28 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 425 437 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SUPERFAMILY SSF81923 225 271 1.83E-5 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SMART SM01086 892 981 2.7E-41 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 SUPERFAMILY SSF81923 7 82 6.15E-10 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 69 1.4E-8 T 12-10-2018 IPR004176 Clp, N-terminal THERU_04330 20f5291b04e39b9a8877a278aa234b10 984 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 236 271 0.024 T 12-10-2018 IPR004176 Clp, N-terminal THERU_00675 9d638d1cf2ae280c35f031998faab231 277 Gene3D G3DSA:3.20.20.70 25 252 2.7E-21 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 PIRSF PIRSF005963 4 277 1.2E-126 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 SMART SM00729 43 250 5.6E-15 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 TIGRFAM TIGR00510 lipA: lipoyl synthase 9 274 8.5E-110 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 Hamap MF_00206 Lipoyl synthase [lipA]. 1 277 130.721 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 SUPERFAMILY SSF102114 13 270 2.88E-60 T 12-10-2018 THERU_00675 9d638d1cf2ae280c35f031998faab231 277 Pfam PF04055 Radical SAM superfamily 49 209 3.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.6E-101 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 Gene3D G3DSA:3.30.70.980 133 205 1.4E-59 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 Pfam PF01709 Transcriptional regulator 5 238 8.2E-96 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 SUPERFAMILY SSF75625 5 246 2.22E-94 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 Gene3D G3DSA:1.10.10.200 1 80 1.1E-35 T 12-10-2018 IPR017856 Integrase-like, N-terminal THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 Gene3D G3DSA:3.30.70.980 84 237 1.4E-59 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02830 d5b0fccd90cdce0f205f6f38138b5eb0 248 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 35.608 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 597 3.2E-231 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 SUPERFAMILY SSF52540 152 421 8.67E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Pfam PF01434 Peptidase family M41 388 596 1.5E-78 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 621 36.817 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Gene3D G3DSA:1.20.58.760 403 609 1.3E-83 T 12-10-2018 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Gene3D G3DSA:3.40.50.300 141 328 3.0E-74 T 12-10-2018 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Gene3D G3DSA:1.10.8.60 329 402 1.8E-30 T 12-10-2018 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 SUPERFAMILY SSF140990 408 603 5.36E-68 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 326 4.6E-46 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_05670 b9837b391e0aaeefd65dda6f0825a623 624 SMART SM00382 189 329 7.9E-28 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Pfam PF02875 Mur ligase family, glutamate ligase domain 276 344 1.7E-11 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 SUPERFAMILY SSF53244 274 408 5.19E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 SUPERFAMILY SSF53623 76 272 2.49E-43 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 2 410 33.103 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Gene3D G3DSA:3.90.190.20 275 407 1.1E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Gene3D G3DSA:3.40.1190.10 73 274 6.5E-49 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 SUPERFAMILY SSF51984 2 73 3.53E-12 T 12-10-2018 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 3 407 1.2E-130 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Gene3D G3DSA:3.40.50.720 1 72 8.4E-11 T 12-10-2018 THERU_06245 6c54100c430ce7de43c5d95b1f01ab43 413 Pfam PF08245 Mur ligase middle domain 89 255 1.0E-26 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THERU_05305 820c5b70830e5267bc735f02f9c1d93d 275 Gene3D G3DSA:3.30.1490.300 66 121 8.2E-15 T 12-10-2018 THERU_05305 820c5b70830e5267bc735f02f9c1d93d 275 SUPERFAMILY SSF53067 41 149 1.75E-7 T 12-10-2018 THERU_05305 820c5b70830e5267bc735f02f9c1d93d 275 Pfam PF11104 Type IV pilus assembly protein PilM; 40 151 1.8E-9 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM THERU_05305 820c5b70830e5267bc735f02f9c1d93d 275 Gene3D G3DSA:3.30.420.40 25 151 8.2E-15 T 12-10-2018 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 425 3.3E-157 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 SUPERFAMILY SSF143968 320 481 6.54E-62 T 12-10-2018 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 450 1.0E-143 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 Gene3D G3DSA:3.40.1670.10 334 449 1.5E-39 T 12-10-2018 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 442 8.4E-196 T 12-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 SUPERFAMILY SSF50475 3 319 4.32E-113 T 12-10-2018 THERU_04750 887c798bf7dc822bd0374de2165cf6d6 483 Gene3D G3DSA:1.20.5.570 450 483 2.4E-6 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 SUPERFAMILY SSF51905 2 299 1.51E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 Gene3D G3DSA:3.50.50.60 4 295 1.5E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 277 6.7E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 264 282 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 35 50 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 1.8E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 Gene3D G3DSA:3.50.50.60 112 235 1.5E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 4.8E-33 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.8E-33 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 4.8E-33 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 4.8E-33 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 4.8E-33 T 12-10-2018 THERU_03440 0ee935b552b3367a77c85ff526e2f084 309 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 SUPERFAMILY SSF51338 3 420 3.35E-28 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 SUPERFAMILY SSF51556 50 344 2.11E-93 T 12-10-2018 IPR032466 Metal-dependent hydrolase THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 Gene3D G3DSA:2.30.40.10 19 409 3.1E-141 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 Gene3D G3DSA:3.20.20.140 51 341 3.1E-141 T 12-10-2018 THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 Pfam PF01979 Amidohydrolase family 48 394 4.6E-71 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THERU_07210 ecd5820bd03da7fad2664df9fd3a9d97 450 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 421 41.979 T 12-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 THERU_07190 9e3df954ebfca41f0bcc62fcf6af3792 142 Gene3D G3DSA:3.10.450.50 19 137 1.7E-5 T 12-10-2018 THERU_07190 9e3df954ebfca41f0bcc62fcf6af3792 142 Pfam PF12870 Domain of unknown function (DUF4878) 21 136 5.6E-21 T 12-10-2018 IPR024267 Domain of unknown function (DUF4878) THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 Pfam PF00551 Formyl transferase 1 181 5.6E-61 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 33.191 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 191 3.1E-80 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 SUPERFAMILY SSF53328 1 200 4.32E-66 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_01590 32f6ccc96bd206003c0a04123bf9a653 216 Gene3D G3DSA:3.40.50.170 1 215 1.9E-86 T 12-10-2018 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 Pfam PF14572 Phosphoribosyl synthetase-associated domain 203 310 1.0E-34 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 Gene3D G3DSA:3.40.50.2020 9 299 1.2E-123 T 12-10-2018 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 Gene3D G3DSA:3.40.50.2020 148 287 1.2E-123 T 12-10-2018 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 121 9.7E-48 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 SUPERFAMILY SSF53271 70 303 1.01E-66 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 311 6.7E-126 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 SMART SM01400 5 121 9.3E-77 T 12-10-2018 THERU_03105 0be3210e5cf6ae7e44820302b249e33f 311 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 5 311 48.655 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 THERU_06725 ea8cce67adee2fd460f71425fafb6a0f 187 Pfam PF12804 MobA-like NTP transferase domain 5 150 2.1E-28 T 12-10-2018 IPR025877 MobA-like NTP transferase THERU_06725 ea8cce67adee2fd460f71425fafb6a0f 187 SUPERFAMILY SSF53448 2 179 3.15E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_06725 ea8cce67adee2fd460f71425fafb6a0f 187 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 183 19.345 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 THERU_06725 ea8cce67adee2fd460f71425fafb6a0f 187 Gene3D G3DSA:3.90.550.10 1 186 7.0E-50 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SMART SM00534 599 786 5.4E-101 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Gene3D G3DSA:3.30.420.110 127 252 2.3E-11 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 680 696 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SUPERFAMILY SSF48334 260 557 1.11E-79 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Pfam PF05188 MutS domain II 127 240 3.2E-11 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Gene3D G3DSA:3.40.50.300 561 850 5.1E-95 T 12-10-2018 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Gene3D G3DSA:3.40.1170.10 2 124 3.1E-47 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SMART SM00533 276 584 1.1E-95 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 9 839 1.2E-248 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Pfam PF01624 MutS domain I 10 121 8.6E-43 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Pfam PF00488 MutS domain V 602 787 2.3E-76 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Pfam PF05190 MutS family domain IV 421 510 1.1E-27 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SUPERFAMILY SSF52540 560 789 6.46E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Pfam PF05192 MutS domain III 263 552 1.4E-30 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Gene3D G3DSA:1.10.1420.10 259 553 2.3E-86 T 12-10-2018 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SUPERFAMILY SSF55271 4 118 5.1E-42 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 PIRSF PIRSF037677 3 146 9.7E-29 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 PIRSF PIRSF037677 229 847 5.9E-118 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 9 834 22.067 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 SUPERFAMILY SSF53150 126 272 9.68E-22 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 THERU_08210 7b4dea465d457275169dc0c95e03ca71 850 Gene3D G3DSA:1.10.1420.10 393 528 2.3E-86 T 12-10-2018 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SMART SM00382 253 433 2.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 Gene3D G3DSA:1.20.120.140 164 453 5.2E-110 T 12-10-2018 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 187 455 59.818 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SMART SM00962 254 455 1.4E-114 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 428 441 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 187 453 1.8E-105 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SUPERFAMILY SSF48452 32 138 7.59E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 Pfam PF00448 SRP54-type protein, GTPase domain 255 453 2.0E-76 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 Gene3D G3DSA:3.40.50.300 254 443 5.2E-110 T 12-10-2018 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SMART SM00963 166 244 3.2E-15 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SUPERFAMILY SSF47364 161 238 1.31E-18 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 Pfam PF02881 SRP54-type protein, helical bundle domain 185 240 2.2E-11 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03610 c55a3c3a9d9d464d4fc1e2d4f7995794 455 SUPERFAMILY SSF52540 251 453 5.13E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Gene3D G3DSA:3.40.1390.10 2 79 2.0E-23 T 12-10-2018 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 5 458 3.2E-166 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Gene3D G3DSA:3.90.190.20 315 460 1.1E-63 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 SUPERFAMILY SSF53244 307 458 9.94E-50 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Pfam PF01225 Mur ligase family, catalytic domain 5 77 5.0E-11 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Pfam PF08245 Mur ligase middle domain 90 287 6.7E-48 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 SUPERFAMILY SSF63418 5 79 3.79E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 458 33.303 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Gene3D G3DSA:3.40.1190.10 81 311 8.7E-72 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 SUPERFAMILY SSF53623 81 304 1.22E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_00800 026be71a77a64a26ea4cccff497a8071 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 392 2.8E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THERU_03885 1247932d812b85734c8fa97319a4b23c 98 SUPERFAMILY SSF81301 2 90 3.05E-23 T 12-10-2018 THERU_03885 1247932d812b85734c8fa97319a4b23c 98 Gene3D G3DSA:3.30.460.10 1 97 2.5E-19 T 12-10-2018 THERU_03885 1247932d812b85734c8fa97319a4b23c 98 Pfam PF01909 Nucleotidyltransferase domain 11 83 1.2E-14 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 SUPERFAMILY SSF55174 2 61 9.92E-16 T 12-10-2018 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 231 7.4E-75 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 Pfam PF01479 S4 domain 2 47 2.3E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 Pfam PF01728 FtsJ-like methyltransferase 56 236 4.6E-24 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 SMART SM00363 1 65 8.4E-19 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 PIRSF PIRSF005578 1 256 3.8E-99 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 Gene3D G3DSA:3.10.290.10 1 58 3.2E-23 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 Gene3D G3DSA:3.40.50.150 59 257 3.2E-72 T 12-10-2018 THERU_01550 46f1358badf25faa734eaa893d9472a1 258 SUPERFAMILY SSF53335 42 238 7.75E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 PIRSF PIRSF006118 1 163 7.2E-64 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 Pfam PF08282 haloacid dehalogenase-like hydrolase 74 135 1.9E-8 T 12-10-2018 THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 Gene3D G3DSA:3.40.50.1000 1 161 2.7E-54 T 12-10-2018 IPR023214 HAD superfamily THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 1 152 1.9E-58 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 SUPERFAMILY SSF56784 1 155 5.12E-40 T 12-10-2018 IPR036412 HAD-like superfamily THERU_04185 5f2a4487944616205c52cad1b3161ab7 163 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 115 6.8E-15 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 217 15.812 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 PRINTS PR00123 ATP synthase A subunit signature 124 139 2.3E-20 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 PRINTS PR00123 ATP synthase A subunit signature 65 81 2.3E-20 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 PRINTS PR00123 ATP synthase A subunit signature 144 166 2.3E-20 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 PRINTS PR00123 ATP synthase A subunit signature 197 212 2.3E-20 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 Gene3D G3DSA:1.20.120.220 58 219 1.6E-36 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 SUPERFAMILY SSF81336 57 210 2.62E-36 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 13 212 2.1E-48 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 ProSitePatterns PS00449 ATP synthase a subunit signature. 147 156 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00890 5f97823d548cb6061fa8e690ee4b98db 219 Pfam PF00119 ATP synthase A chain 11 210 3.6E-55 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Pfam PF12344 Ultra-violet resistance protein B 555 596 2.1E-24 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Pfam PF00271 Helicase conserved C-terminal domain 436 547 3.5E-20 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Gene3D G3DSA:4.10.860.10 606 662 9.4E-12 T 12-10-2018 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Pfam PF02151 UvrB/uvrC motif 626 659 6.8E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 SUPERFAMILY SSF52540 36 576 3.75E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Gene3D G3DSA:3.40.50.300 275 417 2.5E-56 T 12-10-2018 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 SMART SM00490 463 549 1.0E-21 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Gene3D G3DSA:3.40.50.300 1 245 5.2E-73 T 12-10-2018 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 SUPERFAMILY SSF52540 7 418 2.14E-132 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 7 658 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Gene3D G3DSA:3.40.50.300 418 599 6.8E-53 T 12-10-2018 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 SMART SM00487 12 429 1.2E-31 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Hamap MF_00204 UvrABC system protein B [uvrB]. 6 660 43.599 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 SUPERFAMILY SSF46600 621 660 3.01E-10 T 12-10-2018 IPR036876 UVR domain superfamily THERU_02655 13275bf3c8e6f24d605aa5fc336f20c0 664 Pfam PF04851 Type III restriction enzyme, res subunit 17 140 1.4E-9 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THERU_04580 39d17c44fd142e12bcb43f7a8748ea7d 342 Pfam PF00534 Glycosyl transferases group 1 165 316 2.1E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_04580 39d17c44fd142e12bcb43f7a8748ea7d 342 Pfam PF13439 Glycosyltransferase Family 4 14 158 2.4E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_04580 39d17c44fd142e12bcb43f7a8748ea7d 342 SUPERFAMILY SSF53756 8 340 1.7E-67 T 12-10-2018 THERU_04580 39d17c44fd142e12bcb43f7a8748ea7d 342 Gene3D G3DSA:3.40.50.2000 2 166 2.3E-17 T 12-10-2018 THERU_04580 39d17c44fd142e12bcb43f7a8748ea7d 342 Gene3D G3DSA:3.40.50.2000 167 330 6.1E-35 T 12-10-2018 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 2.8E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 6.7E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 322 4.0E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 SUPERFAMILY SSF51246 331 446 3.61E-41 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 SMART SM00878 336 442 4.5E-59 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 Gene3D G3DSA:3.30.470.130 1 447 5.2E-184 T 12-10-2018 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 SUPERFAMILY SSF56059 82 352 2.47E-74 T 12-10-2018 THERU_05445 4f56506115a90ba40eee3ee0aef73daf 475 SUPERFAMILY SSF52440 1 111 3.6E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_08460 23f86a66f2bd4b57f6467b9b31d545f4 271 Pfam PF00950 ABC 3 transport family 11 261 2.2E-49 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THERU_08460 23f86a66f2bd4b57f6467b9b31d545f4 271 SUPERFAMILY SSF81345 9 259 5.62E-31 T 12-10-2018 IPR037294 ABC transporter, BtuC-like THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 62 185 7.6E-9 T 12-10-2018 IPR032551 HTH-type transcriptional repressor, C-terminal THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 1.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 SUPERFAMILY SSF46689 3 74 2.79E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 7.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 7.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_03400 0ee134d2fe820a93e1aa218e4127c8a9 187 Gene3D G3DSA:1.10.357.10 3 186 9.9E-36 T 12-10-2018 THERU_03350 d7488d8bababd2c65494d0f55499a1ae 265 Gene3D G3DSA:3.60.21.10 1 259 1.8E-104 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like THERU_03350 d7488d8bababd2c65494d0f55499a1ae 265 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 256 6.0E-82 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like THERU_03350 d7488d8bababd2c65494d0f55499a1ae 265 Pfam PF13277 YmdB-like protein 4 253 1.5E-101 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like THERU_03350 d7488d8bababd2c65494d0f55499a1ae 265 SUPERFAMILY SSF56300 1 254 2.5E-80 T 12-10-2018 THERU_03350 d7488d8bababd2c65494d0f55499a1ae 265 PIRSF PIRSF004789 1 262 4.6E-92 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like THERU_03125 e4827122702a933a56921a572d4ce30d 753 Gene3D G3DSA:3.40.50.300 288 618 4.5E-71 T 12-10-2018 THERU_03125 e4827122702a933a56921a572d4ce30d 753 Pfam PF01713 Smr domain 678 750 1.3E-12 T 12-10-2018 IPR002625 Smr domain THERU_03125 e4827122702a933a56921a572d4ce30d 753 Gene3D G3DSA:1.10.1420.10 142 222 1.2E-8 T 12-10-2018 THERU_03125 e4827122702a933a56921a572d4ce30d 753 SUPERFAMILY SSF160443 677 750 3.27E-7 T 12-10-2018 IPR036063 Smr domain superfamily THERU_03125 e4827122702a933a56921a572d4ce30d 753 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 750 18.807 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 THERU_03125 e4827122702a933a56921a572d4ce30d 753 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 750 7.9E-212 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 THERU_03125 e4827122702a933a56921a572d4ce30d 753 Gene3D G3DSA:3.30.1370.110 667 751 5.0E-16 T 12-10-2018 THERU_03125 e4827122702a933a56921a572d4ce30d 753 SUPERFAMILY SSF52540 293 506 7.85E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03125 e4827122702a933a56921a572d4ce30d 753 Gene3D G3DSA:1.10.1420.10 35 278 1.2E-8 T 12-10-2018 THERU_03125 e4827122702a933a56921a572d4ce30d 753 PIRSF PIRSF005814 1 751 5.6E-204 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 THERU_03125 e4827122702a933a56921a572d4ce30d 753 SMART SM00463 675 751 3.5E-5 T 12-10-2018 IPR002625 Smr domain THERU_03125 e4827122702a933a56921a572d4ce30d 753 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 404 420 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_03125 e4827122702a933a56921a572d4ce30d 753 SUPERFAMILY SSF48334 34 284 2.09E-22 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily THERU_03125 e4827122702a933a56921a572d4ce30d 753 SMART SM00534 323 507 9.0E-68 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_03125 e4827122702a933a56921a572d4ce30d 753 Pfam PF00488 MutS domain V 327 506 6.1E-31 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THERU_03125 e4827122702a933a56921a572d4ce30d 753 SMART SM00533 5 309 1.6E-16 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 SUPERFAMILY SSF54631 142 263 9.22E-21 T 12-10-2018 THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Pfam PF00571 CBS domain 149 202 3.7E-5 T 12-10-2018 IPR000644 CBS domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Pfam PF00571 CBS domain 214 265 9.3E-5 T 12-10-2018 IPR000644 CBS domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 SMART SM00100 13 130 6.5E-9 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 SMART SM00116 220 267 8.6E-5 T 12-10-2018 IPR000644 CBS domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 SMART SM00116 156 202 0.5 T 12-10-2018 IPR000644 CBS domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Pfam PF03445 Putative nucleotidyltransferase DUF294 292 430 1.6E-43 T 12-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 SUPERFAMILY SSF51206 6 129 3.67E-26 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 468 611 4.0E-49 T 12-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Pfam PF00027 Cyclic nucleotide-binding domain 32 113 2.3E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Gene3D G3DSA:2.60.120.10 2 143 1.7E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold THERU_06740 92937f6b8fdb6152b817298e0e8532d9 617 Gene3D G3DSA:3.10.580.10 144 310 1.6E-25 T 12-10-2018 THERU_06750 e03e018731052befb9e86f4877ee5cba 666 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 44 656 1.1E-232 T 12-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily THERU_06750 e03e018731052befb9e86f4877ee5cba 666 Pfam PF00474 Sodium:solute symporter family 69 238 8.7E-37 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THERU_06750 e03e018731052befb9e86f4877ee5cba 666 Pfam PF00474 Sodium:solute symporter family 348 411 2.7E-5 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THERU_06750 e03e018731052befb9e86f4877ee5cba 666 Pfam PF00474 Sodium:solute symporter family 479 594 3.0E-16 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THERU_06750 e03e018731052befb9e86f4877ee5cba 666 Gene3D G3DSA:1.20.1730.10 324 656 2.2E-28 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily THERU_06750 e03e018731052befb9e86f4877ee5cba 666 Gene3D G3DSA:1.20.1730.10 58 270 3.3E-38 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily THERU_06750 e03e018731052befb9e86f4877ee5cba 666 ProSitePatterns PS00018 EF-hand calcium-binding domain. 450 462 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 276 1.7E-113 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 SUPERFAMILY SSF52518 309 497 3.34E-56 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 SUPERFAMILY SSF52518 3 374 1.33E-74 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 616 1.1E-251 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 ProSitePatterns PS00802 Transketolase signature 2. 418 434 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 SMART SM00861 312 476 1.9E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 SUPERFAMILY SSF52922 483 616 2.88E-35 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Gene3D G3DSA:3.40.50.920 487 619 2.0E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Gene3D G3DSA:3.40.50.970 310 484 5.8E-67 T 12-10-2018 THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Pfam PF02779 Transketolase, pyrimidine binding domain 312 471 3.5E-41 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Pfam PF02780 Transketolase, C-terminal domain 487 608 3.1E-30 T 12-10-2018 IPR033248 Transketolase, C-terminal domain THERU_00535 6ee622640ff382aa5d7ebc4dba231ad1 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 617 45.653 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_01620 b937c43141c4f51d05f99ed5a3fc839f 240 Gene3D G3DSA:3.20.20.370 14 226 1.4E-7 T 12-10-2018 THERU_01620 b937c43141c4f51d05f99ed5a3fc839f 240 SUPERFAMILY SSF88713 18 150 5.0E-10 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THERU_01620 b937c43141c4f51d05f99ed5a3fc839f 240 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 3 142 9.1E-24 T 12-10-2018 IPR018763 Protein of unknown function DUF2334 THERU_05750 c53223b03ad6e89d675aae2f99132fe7 164 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 27 1.3E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05750 c53223b03ad6e89d675aae2f99132fe7 164 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 26 2.5E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05750 c53223b03ad6e89d675aae2f99132fe7 164 Gene3D G3DSA:3.30.700.10 9 148 1.6E-6 T 12-10-2018 THERU_05750 c53223b03ad6e89d675aae2f99132fe7 164 SUPERFAMILY SSF54523 9 138 6.75E-11 T 12-10-2018 THERU_01415 a043c828b653268a87cdc9cb648cf3bc 116 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 115 2.5E-27 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like THERU_01415 a043c828b653268a87cdc9cb648cf3bc 116 Gene3D G3DSA:3.10.490.10 2 116 6.9E-34 T 12-10-2018 THERU_01415 a043c828b653268a87cdc9cb648cf3bc 116 SUPERFAMILY SSF110857 3 114 1.83E-32 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 3 526 8.0E-174 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 653 23.313 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 SUPERFAMILY SSF109604 328 482 2.69E-15 T 12-10-2018 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 306 322 7.1E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 385 404 7.1E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 236 251 7.1E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 42 54 7.1E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 4 17 7.1E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05295 aa72c5fab93a2a4132909b72d8520bee 657 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 654 3.1E-174 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_04605 874419816afbdcb9fcbb613733bd17e3 226 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 1 225 60.109 T 12-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 THERU_04605 874419816afbdcb9fcbb613733bd17e3 226 Pfam PF02146 Sir2 family 8 175 6.7E-55 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 THERU_04605 874419816afbdcb9fcbb613733bd17e3 226 Gene3D G3DSA:3.40.50.1220 2 215 5.0E-88 T 12-10-2018 THERU_04605 874419816afbdcb9fcbb613733bd17e3 226 SUPERFAMILY SSF52467 2 223 2.66E-82 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THERU_04605 874419816afbdcb9fcbb613733bd17e3 226 Gene3D G3DSA:3.30.1600.10 17 145 5.0E-88 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 SMART SM00228 95 166 2.0E-18 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 SMART SM00245 168 357 1.8E-81 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 SUPERFAMILY SSF52096 32 361 6.79E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 Gene3D G3DSA:2.30.42.10 95 182 1.1E-104 T 12-10-2018 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 SUPERFAMILY SSF50156 83 178 1.11E-21 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 Pfam PF03572 Peptidase family S41 192 356 2.0E-56 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 Gene3D G3DSA:3.30.750.44 31 332 1.1E-104 T 12-10-2018 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 Gene3D G3DSA:3.90.226.10 183 354 1.1E-104 T 12-10-2018 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 47 373 4.6E-109 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THERU_00640 a4b4de1461d60a423484d3e1332bed04 410 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 94 162 1.3E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 6.3E-14 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 6.3E-14 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 6.3E-14 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.3E-14 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.6E-23 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 4.6E-23 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 4.6E-23 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.6E-23 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 4.6E-23 T 12-10-2018 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 Gene3D G3DSA:3.50.50.60 2 325 5.8E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 316 1.4E-54 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 SUPERFAMILY SSF51905 1 336 3.55E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_02775 c9aba550f0344b4569a4b4cbc26e1208 461 Gene3D G3DSA:3.50.50.60 34 247 5.8E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06545 cfa62475b5001a40ae487601c60aeda6 998 Hamap MF_01871 UPF0753 protein . 8 982 22.901 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 THERU_06545 cfa62475b5001a40ae487601c60aeda6 998 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 17 967 2.8E-257 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Pfam PF10385 RNA polymerase beta subunit external 1 domain 671 735 3.3E-20 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:2.40.50.100 793 870 7.9E-31 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1110.10 340 454 8.3E-9 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 SUPERFAMILY SSF64484 9 1450 0.0 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1100.10 503 703 9.8E-62 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Pfam PF04560 RNA polymerase Rpb2, domain 7 1375 1449 2.7E-25 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Pfam PF04563 RNA polymerase beta subunit 97 576 2.0E-18 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1800.10 1361 1415 9.1E-12 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1165 1177 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1100.10 16 90 3.3E-9 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1100.10 105 188 6.6E-24 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1110.10 189 293 1.1E-12 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:2.40.50.150 915 1035 1.1E-46 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 112 1447 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Pfam PF00562 RNA polymerase Rpb2, domain 6 796 1373 2.6E-165 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Pfam PF04565 RNA polymerase Rpb2, domain 3 593 660 6.0E-29 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 10 1451 11.891 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:2.40.270.10 872 914 3.9E-7 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:3.90.1100.10 727 792 8.6E-21 T 12-10-2018 THERU_07300 7764e862d3c0dc4e9638eb4dff0785b5 1466 Gene3D G3DSA:2.40.270.10 1138 1351 3.8E-83 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 Gene3D G3DSA:3.40.720.10 16 393 1.0E-98 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 16 396 7.4E-86 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 47 223 2.0E-47 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 Pfam PF01676 Metalloenzyme superfamily 14 396 8.6E-39 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 Gene3D G3DSA:3.30.70.2130 88 236 1.0E-98 T 12-10-2018 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 PIRSF PIRSF006392 10 402 1.7E-124 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 Hamap MF_01402_B 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 13 398 55.215 T 12-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_00075 c9e057e9aa56206e3b42e8d003325834 407 SUPERFAMILY SSF53649 13 369 1.01E-34 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 Gene3D G3DSA:3.30.1330.60 1 108 1.7E-38 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 66 85 1.1E-7 T 12-10-2018 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 48 65 1.1E-7 T 12-10-2018 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 86 106 1.1E-7 T 12-10-2018 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01021 OMPA domain signature 3 25 6.6E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01021 OMPA domain signature 48 64 6.6E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 PRINTS PR01021 OMPA domain signature 33 48 6.6E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 SUPERFAMILY SSF103088 1 103 7.19E-37 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_01345 7eb706c41516e0dccec12315c058d3aa 109 Pfam PF00691 OmpA family 3 97 2.1E-26 T 12-10-2018 IPR006665 OmpA-like domain THERU_00120 f9723fb014e288ff3e254132917b6b05 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 192 20.467 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THERU_00120 f9723fb014e288ff3e254132917b6b05 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 188 1.9E-56 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THERU_00120 f9723fb014e288ff3e254132917b6b05 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 183 1.4E-51 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THERU_00120 f9723fb014e288ff3e254132917b6b05 193 SMART SM01207 8 184 1.7E-77 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 36.251 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 204 4.2E-81 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 SUPERFAMILY SSF50447 3 213 3.27E-73 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 Pfam PF00297 Ribosomal protein L3 95 168 1.1E-16 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 ProSitePatterns PS00474 Ribosomal protein L3 signature. 103 126 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 Gene3D G3DSA:2.40.30.10 123 210 2.2E-11 T 12-10-2018 THERU_07335 8d82d0c006540c9de76e7d7be2614165 234 Gene3D G3DSA:2.40.50.620 33 97 8.9E-17 T 12-10-2018 THERU_01545 6f5fb4cd3eab9f2d54ff58ec4fbc5251 79 Pfam PF02325 YGGT family 8 77 1.3E-16 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 THERU_03425 e33129b2d4cd19e910a9c0b3bca692e4 117 Gene3D G3DSA:3.40.50.720 1 111 3.2E-10 T 12-10-2018 THERU_03425 e33129b2d4cd19e910a9c0b3bca692e4 117 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 99 1.7E-7 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THERU_03425 e33129b2d4cd19e910a9c0b3bca692e4 117 SUPERFAMILY SSF51735 1 106 1.69E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 Gene3D G3DSA:3.30.70.20 32 90 1.6E-5 T 12-10-2018 THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 SUPERFAMILY SSF54862 30 125 4.74E-9 T 12-10-2018 THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 Pfam PF02754 Cysteine-rich domain 322 404 3.1E-4 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 Pfam PF02754 Cysteine-rich domain 191 275 5.5E-9 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_02205 29d600e071cd3f0d3d104f531b2e1faf 425 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_06265 4b9fe3dcc63951c9362951d1ec4aed29 182 Gene3D G3DSA:3.40.50.300 1 181 2.5E-33 T 12-10-2018 THERU_06265 4b9fe3dcc63951c9362951d1ec4aed29 182 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 168 7.0E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_06265 4b9fe3dcc63951c9362951d1ec4aed29 182 Pfam PF03029 Conserved hypothetical ATP binding protein 40 147 8.5E-13 T 12-10-2018 IPR004130 GPN-loop GTPase THERU_06265 4b9fe3dcc63951c9362951d1ec4aed29 182 SUPERFAMILY SSF52540 6 178 1.09E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02190 59d0ec131344fcffe805745e584d10f2 266 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 126 2.0E-28 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 SUPERFAMILY SSF55347 128 236 3.27E-29 T 12-10-2018 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 264 2.1E-40 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 265 31.583 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 PIRSF PIRSF000161 1 266 8.7E-76 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 Gene3D G3DSA:3.30.360.10 128 234 7.8E-85 T 12-10-2018 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 265 7.6E-74 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 Gene3D G3DSA:3.40.50.720 5 264 7.8E-85 T 12-10-2018 THERU_02190 59d0ec131344fcffe805745e584d10f2 266 SUPERFAMILY SSF51735 1 266 1.14E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_02190 59d0ec131344fcffe805745e584d10f2 266 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 604 1.7E-267 T 12-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 Gene3D G3DSA:2.40.50.100 534 610 6.4E-25 T 12-10-2018 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 Pfam PF00364 Biotin-requiring enzyme 543 608 4.3E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 Pfam PF00682 HMGL-like 3 261 2.8E-40 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 Pfam PF02436 Conserved carboxylase domain 292 479 8.5E-56 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 SUPERFAMILY SSF89000 297 450 2.0E-49 T 12-10-2018 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 Gene3D G3DSA:3.20.20.70 1 457 4.9E-161 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 SUPERFAMILY SSF51230 539 608 4.06E-21 T 12-10-2018 IPR011053 Single hybrid motif THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 565 582 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_07945 ed493fc0599870e64e49f4fc83bd9f0a 612 SUPERFAMILY SSF51569 1 301 6.89E-85 T 12-10-2018 THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 Gene3D G3DSA:1.20.1510.10 4 197 4.2E-47 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 Pfam PF01545 Cation efflux family 8 197 8.2E-39 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 278 1.2E-66 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 Gene3D G3DSA:3.30.70.1350 198 279 1.9E-14 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 SUPERFAMILY SSF160240 200 279 1.96E-15 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 292 366 2.7E-5 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 SUPERFAMILY SSF161111 5 198 1.23E-40 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THERU_03415 999f42f2b3979c10c23b5d76e580a6ad 385 Pfam PF16916 Dimerisation domain of Zinc Transporter 202 277 1.4E-15 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain THERU_06805 c74c877122abc055a1718b2d318a0e77 209 Pfam PF00677 Lumazine binding domain 3 84 4.3E-18 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_06805 c74c877122abc055a1718b2d318a0e77 209 Pfam PF00677 Lumazine binding domain 97 181 6.8E-22 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_06805 c74c877122abc055a1718b2d318a0e77 209 SUPERFAMILY SSF63380 90 192 8.5E-30 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THERU_06805 c74c877122abc055a1718b2d318a0e77 209 Gene3D G3DSA:2.40.30.20 99 202 2.3E-31 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_06805 c74c877122abc055a1718b2d318a0e77 209 Gene3D G3DSA:2.40.30.20 1 86 6.2E-25 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_06805 c74c877122abc055a1718b2d318a0e77 209 SUPERFAMILY SSF63380 1 90 2.64E-23 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THERU_06805 c74c877122abc055a1718b2d318a0e77 209 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 3.9E-64 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_06805 c74c877122abc055a1718b2d318a0e77 209 PIRSF PIRSF000498 1 205 3.1E-69 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_00325 30481339da8c2a1b0f8d19998eea7a0d 356 Gene3D G3DSA:2.40.10.220 227 347 1.5E-8 T 12-10-2018 THERU_00325 30481339da8c2a1b0f8d19998eea7a0d 356 SUPERFAMILY SSF141371 260 346 3.14E-6 T 12-10-2018 THERU_00325 30481339da8c2a1b0f8d19998eea7a0d 356 Pfam PF07238 PilZ domain 255 342 1.7E-8 T 12-10-2018 IPR009875 PilZ domain GO:0035438 THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 SUPERFAMILY SSF55315 1 71 6.12E-14 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 Gene3D G3DSA:3.30.1330.30 1 72 1.1E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 Pfam PF00588 SpoU rRNA Methylase family 90 229 9.4E-39 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 2 232 7.9E-60 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 Gene3D G3DSA:3.40.1280.10 78 234 2.2E-47 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 SUPERFAMILY SSF75217 63 235 1.23E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 2 72 1.3E-20 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THERU_05790 4605b002c3e687bbfcdfdb7ab9ce11dc 241 SMART SM00967 2 75 1.6E-20 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THERU_05185 b0c812e530af315006897830441b1c59 251 Gene3D G3DSA:3.20.20.70 1 251 6.0E-117 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05185 b0c812e530af315006897830441b1c59 251 Pfam PF00977 Histidine biosynthesis protein 5 233 3.0E-95 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 THERU_05185 b0c812e530af315006897830441b1c59 251 TIGRFAM TIGR03572 WbuZ: glycosyl amidation-associated protein WbuZ 1 230 2.6E-92 T 12-10-2018 IPR020021 Glycosyl amidation-associated protein, WbuZ GO:0016833 THERU_05185 b0c812e530af315006897830441b1c59 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 51.18 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 THERU_05185 b0c812e530af315006897830441b1c59 251 SUPERFAMILY SSF51366 1 250 1.02E-89 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_05185 b0c812e530af315006897830441b1c59 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 250 4.6E-124 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 THERU_03600 64d85495a81aa36375962f5781b4ffc2 63 SUPERFAMILY SSF47598 5 44 4.45E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THERU_07985 5248594c6e9da7883b240f787da15cf6 205 Pfam PF12697 Alpha/beta hydrolase family 19 189 2.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THERU_07985 5248594c6e9da7883b240f787da15cf6 205 SUPERFAMILY SSF53474 1 192 8.23E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold THERU_07985 5248594c6e9da7883b240f787da15cf6 205 Gene3D G3DSA:3.40.50.1820 1 197 9.8E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold THERU_08020 a930e96a0f037cecf509b9004134be74 430 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 9 423 39.422 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_08020 a930e96a0f037cecf509b9004134be74 430 SUPERFAMILY SSF55205 10 425 2.45E-128 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THERU_08020 a930e96a0f037cecf509b9004134be74 430 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 413 2.4E-94 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THERU_08020 a930e96a0f037cecf509b9004134be74 430 Gene3D G3DSA:3.65.10.10 14 420 4.4E-157 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THERU_08020 a930e96a0f037cecf509b9004134be74 430 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 11 422 7.7E-158 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_08020 a930e96a0f037cecf509b9004134be74 430 Gene3D G3DSA:3.65.10.10 29 236 4.4E-157 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THERU_03215 aa900105450e591a2ee67831eba21744 405 SUPERFAMILY SSF52402 1 203 1.72E-49 T 12-10-2018 THERU_03215 aa900105450e591a2ee67831eba21744 405 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03215 aa900105450e591a2ee67831eba21744 405 Gene3D G3DSA:3.90.1260.10 172 402 9.1E-93 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03215 aa900105450e591a2ee67831eba21744 405 SUPERFAMILY SSF69864 171 396 5.49E-91 T 12-10-2018 THERU_03215 aa900105450e591a2ee67831eba21744 405 Gene3D G3DSA:3.40.50.620 2 171 2.7E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_03215 aa900105450e591a2ee67831eba21744 405 Pfam PF00764 Arginosuccinate synthase 5 391 8.0E-161 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03215 aa900105450e591a2ee67831eba21744 405 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 7 15 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03215 aa900105450e591a2ee67831eba21744 405 TIGRFAM TIGR00032 argG: argininosuccinate synthase 3 395 3.3E-156 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03215 aa900105450e591a2ee67831eba21744 405 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 397 54.397 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Pfam PF00158 Sigma-54 interaction domain 197 364 5.6E-72 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 479 499 2.0E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 462 479 2.0E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Gene3D G3DSA:3.30.450.40 5 176 7.9E-36 T 12-10-2018 IPR029016 GAF-like domain superfamily THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 283 298 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 SMART SM00382 217 360 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Pfam PF02954 Bacterial regulatory protein, Fis family 456 496 8.4E-15 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 221 234 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Gene3D G3DSA:1.10.8.60 368 432 1.8E-25 T 12-10-2018 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 SUPERFAMILY SSF46689 409 498 2.91E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 SUPERFAMILY SSF55781 9 186 8.59E-16 T 12-10-2018 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Pfam PF13185 GAF domain 26 139 4.9E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 SUPERFAMILY SSF52540 196 429 4.81E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 SMART SM00065 26 174 2.2E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Gene3D G3DSA:3.40.50.300 185 367 1.5E-69 T 12-10-2018 THERU_07040 e2b56a7be86be17d7414947a4d4f5913 503 Gene3D G3DSA:1.10.10.60 433 503 1.4E-17 T 12-10-2018 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 SMART SM00382 211 392 2.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 3.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 3.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 210 225 3.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 SUPERFAMILY SSF54211 11 168 4.55E-38 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 Gene3D G3DSA:3.40.50.300 174 502 1.9E-61 T 12-10-2018 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 395 2.1E-92 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 Gene3D G3DSA:3.30.230.10 20 166 8.6E-17 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 SUPERFAMILY SSF52540 190 503 1.15E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 402 498 6.3E-34 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 140 8.6E-49 T 12-10-2018 THERU_02810 38c9c05b27ae035b1d3e0c8333e4f5bc 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 498 5.1E-186 T 12-10-2018 IPR004482 Mg chelatase-related protein THERU_08200 fc993bcbb80825e1f084bf4c3cdf737b 155 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 148 1.1E-37 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THERU_08200 fc993bcbb80825e1f084bf4c3cdf737b 155 Gene3D G3DSA:3.40.50.10420 1 155 8.9E-53 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily THERU_08200 fc993bcbb80825e1f084bf4c3cdf737b 155 SUPERFAMILY SSF100950 2 153 1.95E-43 T 12-10-2018 IPR037171 NagB/RpiA transferase-like THERU_08200 fc993bcbb80825e1f084bf4c3cdf737b 155 PIRSF PIRSF006806 1 151 1.1E-39 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THERU_08200 fc993bcbb80825e1f084bf4c3cdf737b 155 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 1 148 1.2E-40 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THERU_01460 56ff37718fb9ca6a409ed0d2f725427c 62 Gene3D G3DSA:4.10.830.10 1 62 2.2E-27 T 12-10-2018 THERU_01460 56ff37718fb9ca6a409ed0d2f725427c 62 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 62 24.896 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z THERU_01460 56ff37718fb9ca6a409ed0d2f725427c 62 Pfam PF00253 Ribosomal protein S14p/S29e 12 61 1.3E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01460 56ff37718fb9ca6a409ed0d2f725427c 62 ProSitePatterns PS00527 Ribosomal protein S14 signature. 24 46 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01460 56ff37718fb9ca6a409ed0d2f725427c 62 SUPERFAMILY SSF57716 12 62 1.14E-19 T 12-10-2018 THERU_03515 698e19aad42e86d16d6fd52f241b24c4 519 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 356 428 1.1E-5 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_03515 698e19aad42e86d16d6fd52f241b24c4 519 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 268 343 1.2E-15 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_01090 cae5d362ddbe50852100133467a0704a 310 Pfam PF00698 Acyl transferase domain 6 291 1.8E-45 T 12-10-2018 IPR014043 Acyl transferase THERU_01090 cae5d362ddbe50852100133467a0704a 310 SUPERFAMILY SSF55048 128 196 2.62E-18 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding THERU_01090 cae5d362ddbe50852100133467a0704a 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 297 1.7E-42 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain THERU_01090 cae5d362ddbe50852100133467a0704a 310 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 2.1E-95 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THERU_01090 cae5d362ddbe50852100133467a0704a 310 SUPERFAMILY SSF52151 4 308 1.91E-73 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THERU_01090 cae5d362ddbe50852100133467a0704a 310 PIRSF PIRSF000446 1 310 9.7E-99 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THERU_01090 cae5d362ddbe50852100133467a0704a 310 Gene3D G3DSA:3.40.366.10 7 285 1.2E-93 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 THERU_01090 cae5d362ddbe50852100133467a0704a 310 Gene3D G3DSA:3.30.70.250 125 196 1.2E-93 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 SUPERFAMILY SSF54211 225 395 3.22E-50 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Gene3D G3DSA:3.30.230.10 224 401 3.2E-60 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 SMART SM00387 36 180 1.9E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Gene3D G3DSA:3.30.565.10 7 223 9.5E-92 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Pfam PF00204 DNA gyrase B 225 394 8.7E-54 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 SUPERFAMILY SSF55874 11 222 4.19E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 179 9.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Pfam PF01751 Toprim domain 423 534 3.9E-19 T 12-10-2018 IPR006171 TOPRIM domain THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 791 92.454 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Gene3D G3DSA:3.40.50.670 402 581 7.3E-80 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Gene3D G3DSA:3.40.50.670 692 791 1.4E-24 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 11 21 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 316 332 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 200 213 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 744 756 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 760 776 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 474 483 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 224 246 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 364 378 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 185 200 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR01159 DNA gyrase subunit B signature 378 398 4.0E-51 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 791 2.2E-290 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 SUPERFAMILY SSF56719 398 784 1.12E-88 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 SMART SM00433 40 784 2.7E-288 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 719 779 5.1E-31 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 508 525 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 40 55 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 118 132 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 490 506 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 723 739 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 75 88 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 272 285 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 528 540 8.0E-74 T 12-10-2018 THERU_04320 7413a1041ad6b704b2a9bd40ef05531e 791 PRINTS PR00418 DNA topoisomerase II family signature 424 438 8.0E-74 T 12-10-2018 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 172 3.3E-61 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 SUPERFAMILY SSF54364 5 78 5.36E-31 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 SUPERFAMILY SSF55200 85 172 3.14E-29 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 Gene3D G3DSA:3.30.110.10 77 172 4.8E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 Gene3D G3DSA:3.10.20.80 1 76 7.5E-36 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 172 30.0 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 8.4E-35 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THERU_04515 4b11b256d4851eedb967818d8d5f7886 172 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 3.3E-32 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 307 3.5E-38 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 330 5.5E-113 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 2 330 40.033 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 Gene3D G3DSA:3.20.20.70 2 330 2.2E-99 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 SUPERFAMILY SSF102114 4 295 3.01E-70 T 12-10-2018 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 Pfam PF04055 Radical SAM superfamily 15 175 2.7E-26 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 Pfam PF13353 4Fe-4S single cluster domain 18 105 5.9E-8 T 12-10-2018 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_06070 68e715ad317589d5940f2e00aa089a08 330 SMART SM00729 11 214 8.4E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 Gene3D G3DSA:3.40.50.720 1 182 2.6E-80 T 12-10-2018 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.166 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 Gene3D G3DSA:1.10.3730.40 183 333 1.3E-68 T 12-10-2018 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 1.9E-143 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 SUPERFAMILY SSF48179 184 328 1.43E-71 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 PIRSF PIRSF000116 202 330 3.6E-17 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 PIRSF PIRSF000116 5 206 6.3E-42 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 SUPERFAMILY SSF51735 3 183 1.98E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 1.5E-77 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_03030 295979cef8d8b1d42a0a2fbbba83c741 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 326 4.8E-66 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Gene3D G3DSA:3.90.960.10 240 386 2.6E-226 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Pfam PF04073 Aminoacyl-tRNA editing domain 256 375 1.2E-30 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 37.541 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 456 8.9E-44 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.3E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.3E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.3E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.3E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 SUPERFAMILY SSF55826 221 387 2.62E-32 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Pfam PF03129 Anticodon binding domain 475 563 1.3E-15 T 12-10-2018 IPR004154 Anticodon-binding THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 SUPERFAMILY SSF55681 10 473 1.16E-88 T 12-10-2018 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 SUPERFAMILY SSF52954 460 567 3.78E-26 T 12-10-2018 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Gene3D G3DSA:3.40.50.800 4 549 2.6E-226 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 Gene3D G3DSA:3.30.930.10 11 462 2.6E-226 T 12-10-2018 THERU_01195 e05dd54539ace5622b7a0a22b368548d 570 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 3.5E-199 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THERU_08425 8e52430f3d84cecde30782966393b059 202 Gene3D G3DSA:3.30.160.100 2 117 9.8E-20 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like THERU_08425 8e52430f3d84cecde30782966393b059 202 Gene3D G3DSA:3.30.505.50 152 197 1.8E-10 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily THERU_08425 8e52430f3d84cecde30782966393b059 202 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 111 4.2E-17 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 THERU_08425 8e52430f3d84cecde30782966393b059 202 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 115 1.6E-23 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 THERU_08425 8e52430f3d84cecde30782966393b059 202 SUPERFAMILY SSF69754 1 118 5.1E-16 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like THERU_08425 8e52430f3d84cecde30782966393b059 202 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 140 194 5.3E-13 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal THERU_08425 8e52430f3d84cecde30782966393b059 202 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 198 19.808 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid THERU_08125 98d59f97c7c917282b0285f90627bc61 428 Gene3D G3DSA:1.10.3110.10 95 193 1.9E-120 T 12-10-2018 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 SUPERFAMILY SSF54373 277 376 1.84E-21 T 12-10-2018 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 Pfam PF01593 Flavin containing amine oxidoreductase 11 425 2.0E-50 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 3 428 3.8E-112 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 SUPERFAMILY SSF51905 3 425 6.47E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_08125 98d59f97c7c917282b0285f90627bc61 428 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 6.8E-6 T 12-10-2018 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 6.8E-6 T 12-10-2018 THERU_08125 98d59f97c7c917282b0285f90627bc61 428 Gene3D G3DSA:3.50.50.60 4 419 1.9E-120 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_08125 98d59f97c7c917282b0285f90627bc61 428 Gene3D G3DSA:3.90.660.20 39 376 1.9E-120 T 12-10-2018 THERU_02505 a52175aa1727027d985397e79e9130ad 485 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 12 472 16.349 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THERU_02505 a52175aa1727027d985397e79e9130ad 485 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 15 471 3.5E-129 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THERU_02505 a52175aa1727027d985397e79e9130ad 485 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 9.1E-8 T 12-10-2018 THERU_02505 a52175aa1727027d985397e79e9130ad 485 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 9.1E-8 T 12-10-2018 THERU_02505 a52175aa1727027d985397e79e9130ad 485 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 9.1E-8 T 12-10-2018 THERU_02505 a52175aa1727027d985397e79e9130ad 485 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 9.1E-8 T 12-10-2018 THERU_02505 a52175aa1727027d985397e79e9130ad 485 Pfam PF00361 Proton-conducting membrane transporter 130 417 6.9E-61 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 4 1147 1.7E-289 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 PIRSF PIRSF005719 2 1153 4.8E-232 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Gene3D G3DSA:3.40.50.300 2 179 4.0E-50 T 12-10-2018 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 SUPERFAMILY SSF52540 820 1143 1.44E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 1139 4.4E-57 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Gene3D G3DSA:3.40.50.300 996 1152 1.4E-45 T 12-10-2018 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 SUPERFAMILY SSF75553 463 671 4.84E-49 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Gene3D G3DSA:3.30.70.1620 568 650 3.5E-42 T 12-10-2018 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 SUPERFAMILY SSF57997 202 486 1.05E-6 T 12-10-2018 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 SMART SM00968 507 624 4.3E-40 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 4 1146 1.1E-185 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Pfam PF06470 SMC proteins Flexible Hinge Domain 507 623 4.5E-34 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Hamap MF_01894 Chromosome partition protein Smc [smc]. 3 1150 19.142 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 SUPERFAMILY SSF52540 4 285 6.2E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08355 78b85ca305e9cab8b24a56154aa0abc9 1154 Gene3D G3DSA:1.20.1060.20 504 654 3.5E-42 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 SUPERFAMILY SSF50447 425 508 7.9E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Gene3D G3DSA:3.40.50.300 249 423 1.6E-71 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Gene3D G3DSA:2.40.30.10 653 749 1.9E-34 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 SUPERFAMILY SSF50447 653 745 2.5E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 PRINTS PR00449 Transforming protein P21 ras signature 294 316 2.8E-5 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 PRINTS PR00449 Transforming protein P21 ras signature 393 415 2.8E-5 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 PRINTS PR00449 Transforming protein P21 ras signature 352 365 2.8E-5 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 PRINTS PR00449 Transforming protein P21 ras signature 254 275 2.8E-5 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 749 17.117 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 173 748 1.5E-245 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Gene3D G3DSA:1.10.10.2480 1 68 9.5E-8 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Gene3D G3DSA:3.40.50.10050 545 652 1.2E-36 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 SUPERFAMILY SSF52540 240 420 5.95E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 SUPERFAMILY SSF52156 534 658 1.83E-34 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Pfam PF00009 Elongation factor Tu GTP binding domain 255 413 4.1E-36 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 256 411 2.6E-34 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Gene3D G3DSA:2.40.30.10 424 538 9.5E-46 T 12-10-2018 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 180 226 3.5E-6 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 1.4E-11 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 Pfam PF11987 Translation-initiation factor 2 536 641 4.0E-36 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 THERU_01130 eee2a79ffdc70b02eb0a576da1b8910f 751 ProSitePatterns PS01176 Initiation factor 2 signature. 702 724 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 269 286 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 320 333 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 25 41 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 117 129 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 248 263 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 62 80 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 PRINTS PR00992 Alanine racemase signature 231 246 3.4E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 Pfam PF01168 Alanine racemase, N-terminal domain 8 204 3.3E-41 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 Pfam PF00842 Alanine racemase, C-terminal domain 215 336 9.4E-36 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 Gene3D G3DSA:3.20.20.10 10 207 2.9E-91 T 12-10-2018 IPR029066 PLP-binding barrel THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 TIGRFAM TIGR00492 alr: alanine racemase 5 337 1.0E-82 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 Gene3D G3DSA:2.40.37.10 8 335 2.9E-91 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 SUPERFAMILY SSF50621 207 337 3.49E-41 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 SMART SM01005 215 338 9.4E-51 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 SUPERFAMILY SSF51419 8 216 1.88E-44 T 12-10-2018 IPR029066 PLP-binding barrel THERU_02740 0568656ba7ace749676dd6c0f37ea306 338 Hamap MF_01201 Alanine racemase. 1 338 28.544 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SMART SM00957 6 444 8.6E-256 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Pfam PF07517 SecA DEAD-like domain 6 444 8.8E-124 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Gene3D G3DSA:3.40.50.300 459 673 8.4E-95 T 12-10-2018 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SUPERFAMILY SSF81767 287 410 6.54E-49 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Pfam PF07516 SecA Wing and Scaffold domain 671 877 1.6E-55 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SMART SM00958 288 400 1.6E-71 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 ProSitePatterns PS01312 SecA family signature. 542 557 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 72 96 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 455 468 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 418 435 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 110 124 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 126 136 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 PRINTS PR00906 SecA protein signature 381 403 9.7E-51 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SUPERFAMILY SSF52540 459 672 4.77E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SUPERFAMILY SSF81886 674 889 1.57E-62 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Pfam PF01043 SecA preprotein cross-linking domain 293 400 5.4E-45 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Gene3D G3DSA:1.10.3060.10 675 880 2.0E-60 T 12-10-2018 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 SUPERFAMILY SSF52540 6 457 2.27E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 879 19.894 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_04125 58055bfa2c51943729c5ad849a84e3ea 930 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 219 862 1.8E-273 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 Pfam PF00330 Aconitase family (aconitate hydratase) 7 410 2.7E-104 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 SUPERFAMILY SSF53732 1 419 6.02E-155 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 418 51.765 T 12-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 Gene3D G3DSA:3.30.499.10 273 428 6.9E-59 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 ProSitePatterns PS01244 Aconitase family signature 2. 351 364 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 Gene3D G3DSA:3.30.499.20 4 269 7.2E-108 T 12-10-2018 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 ProSitePatterns PS00450 Aconitase family signature 1. 291 307 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 416 5.7E-173 T 12-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 102 110 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 189 202 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 127 142 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 351 364 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 113 126 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 PRINTS PR00415 Aconitase family signature 203 216 1.0E-17 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 416 1.3E-207 T 12-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 THERU_05665 38a334ba21da4ed1fdbbe07315e64e29 429 TIGRFAM TIGR02083 LEU2: 3-isopropylmalate dehydratase, large subunit 3 418 2.7E-206 T 12-10-2018 IPR011823 3-isopropylmalate dehydratase, large subunit, bacteria GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THERU_00575 af3dcfad8d7caddfafd4dc004a773778 132 Pfam PF01894 Uncharacterised protein family UPF0047 16 129 5.0E-42 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 THERU_00575 af3dcfad8d7caddfafd4dc004a773778 132 SUPERFAMILY SSF111038 4 130 2.22E-46 T 12-10-2018 IPR035917 YjbQ-like superfamily THERU_00575 af3dcfad8d7caddfafd4dc004a773778 132 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 130 1.4E-47 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 THERU_00575 af3dcfad8d7caddfafd4dc004a773778 132 Gene3D G3DSA:2.60.120.460 1 131 1.5E-51 T 12-10-2018 IPR035917 YjbQ-like superfamily THERU_00575 af3dcfad8d7caddfafd4dc004a773778 132 PIRSF PIRSF004681 1 132 5.7E-46 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 THERU_02695 ee98916e689124798ffba38652370536 503 Pfam PF01743 Poly A polymerase head domain 37 171 7.3E-22 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THERU_02695 ee98916e689124798ffba38652370536 503 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 199 257 6.6E-11 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THERU_02695 ee98916e689124798ffba38652370536 503 TIGRFAM TIGR00277 HDIG: HDIG domain 312 369 1.9E-10 T 12-10-2018 IPR006675 HDIG domain THERU_02695 ee98916e689124798ffba38652370536 503 SUPERFAMILY SSF81891 169 500 1.44E-39 T 12-10-2018 THERU_02695 ee98916e689124798ffba38652370536 503 SUPERFAMILY SSF81301 19 167 7.19E-17 T 12-10-2018 THERU_02695 ee98916e689124798ffba38652370536 503 Gene3D G3DSA:1.10.3090.10 169 498 1.8E-31 T 12-10-2018 THERU_02695 ee98916e689124798ffba38652370536 503 Gene3D G3DSA:3.30.460.10 1 166 8.8E-56 T 12-10-2018 THERU_02695 ee98916e689124798ffba38652370536 503 Pfam PF01966 HD domain 273 383 1.6E-13 T 12-10-2018 IPR006674 HD domain THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 SMART SM00994 7 47 9.2E-16 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Gene3D G3DSA:3.30.50.30 2 47 2.5E-15 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 SUPERFAMILY SSF57716 9 44 1.4E-7 T 12-10-2018 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 SMART SM00382 109 271 3.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 306 1.5E-47 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Gene3D G3DSA:3.40.50.300 52 310 4.9E-108 T 12-10-2018 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 52.083 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 SUPERFAMILY SSF52540 57 395 2.37E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 SMART SM01086 312 399 2.6E-34 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Gene3D G3DSA:1.10.8.60 311 412 1.4E-42 T 12-10-2018 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 405 5.2E-194 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 5.7E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_05715 6fe0c5274d7a33315299afdd9cd207be 412 Pfam PF06689 ClpX C4-type zinc finger 9 46 1.4E-16 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 460 1.8E-164 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 Gene3D G3DSA:3.40.50.620 1 316 1.2E-143 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01350 b0847844abea01f3a6d4879c43206d57 466 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 8 19 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 5 17 1.8E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 30 1.8E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 1.8E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 1.8E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 47 1.8E-27 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 Gene3D G3DSA:1.10.10.350 368 466 8.4E-20 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 SUPERFAMILY SSF48163 301 462 6.02E-34 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 Gene3D G3DSA:1.10.8.70 318 364 7.8E-7 T 12-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 SUPERFAMILY SSF52374 1 300 4.83E-115 T 12-10-2018 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 307 1.7E-113 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 THERU_01350 b0847844abea01f3a6d4879c43206d57 466 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 462 32.938 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THERU_05770 33fa07cd67f0fdf2c5faaca38d4ac12e 660 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 57 439 3.5E-13 T 12-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 THERU_05770 33fa07cd67f0fdf2c5faaca38d4ac12e 660 Gene3D G3DSA:3.40.1380.40 386 523 4.2E-19 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 Gene3D G3DSA:3.30.420.40 3 272 1.3E-56 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 SUPERFAMILY SSF53067 1 274 6.91E-33 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 337 597 1.3E-39 T 12-10-2018 IPR008275 CoA enzyme activase THERU_07010 eddcac337e189b3063617a934188ed29 717 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 3 219 3.4E-25 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 THERU_07010 eddcac337e189b3063617a934188ed29 717 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 339 598 4.0E-46 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 THERU_07010 eddcac337e189b3063617a934188ed29 717 Gene3D G3DSA:3.30.420.40 339 598 1.4E-67 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 Gene3D G3DSA:3.30.420.40 96 259 1.3E-56 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 Gene3D G3DSA:3.30.420.40 433 583 1.4E-67 T 12-10-2018 THERU_07010 eddcac337e189b3063617a934188ed29 717 SUPERFAMILY SSF53067 338 598 2.94E-34 T 12-10-2018 THERU_07065 696659d14687b83a6f1140d8df537229 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 1.1E-206 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THERU_07065 696659d14687b83a6f1140d8df537229 469 SMART SM01230 105 379 2.9E-137 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THERU_07065 696659d14687b83a6f1140d8df537229 469 SUPERFAMILY SSF55931 106 468 1.77E-131 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THERU_07065 696659d14687b83a6f1140d8df537229 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 98 4.8E-31 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THERU_07065 696659d14687b83a6f1140d8df537229 469 Gene3D G3DSA:3.30.590.10 108 457 2.2E-143 T 12-10-2018 THERU_07065 696659d14687b83a6f1140d8df537229 469 Pfam PF00120 Glutamine synthetase, catalytic domain 106 466 6.7E-133 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THERU_07065 696659d14687b83a6f1140d8df537229 469 SUPERFAMILY SSF54368 6 103 9.29E-36 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THERU_07065 696659d14687b83a6f1140d8df537229 469 Gene3D G3DSA:3.10.20.70 5 107 2.9E-39 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Pfam PF03143 Elongation factor Tu C-terminal domain 308 403 3.8E-35 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THERU_07325 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF50447 214 311 3.53E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Pfam PF03144 Elongation factor Tu domain 2 234 303 7.2E-19 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:2.40.30.10 348 404 3.5E-28 T 12-10-2018 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF50465 308 404 7.2E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:3.40.50.300 1 212 1.1E-67 T 12-10-2018 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 404 4.0E-213 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF52540 8 235 1.41E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07325 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 135 144 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Pfam PF00009 Elongation factor Tu GTP binding domain 10 210 1.0E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:2.40.30.10 215 344 2.2E-54 T 12-10-2018 THERU_07325 e753117673be3a77f778bf2d64d37c52 405 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 405 59.967 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Pfam PF03143 Elongation factor Tu C-terminal domain 308 403 3.8E-35 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THERU_07250 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF50447 214 311 3.53E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Pfam PF03144 Elongation factor Tu domain 2 234 303 7.2E-19 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:2.40.30.10 348 404 3.5E-28 T 12-10-2018 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF50465 308 404 7.2E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:3.40.50.300 1 212 1.1E-67 T 12-10-2018 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 404 4.0E-213 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 SUPERFAMILY SSF52540 8 235 1.41E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07250 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 135 144 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Pfam PF00009 Elongation factor Tu GTP binding domain 10 210 1.0E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Gene3D G3DSA:2.40.30.10 215 344 2.2E-54 T 12-10-2018 THERU_07250 e753117673be3a77f778bf2d64d37c52 405 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 405 59.967 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_03180 11673e778fb35c233d79326730902df4 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 1.1E-86 T 12-10-2018 THERU_03180 11673e778fb35c233d79326730902df4 272 SUPERFAMILY SSF51735 5 255 1.12E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03180 11673e778fb35c233d79326730902df4 272 PIRSF PIRSF000094 1 260 1.0E-119 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THERU_03180 11673e778fb35c233d79326730902df4 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03180 11673e778fb35c233d79326730902df4 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03180 11673e778fb35c233d79326730902df4 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03180 11673e778fb35c233d79326730902df4 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03180 11673e778fb35c233d79326730902df4 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03180 11673e778fb35c233d79326730902df4 272 Gene3D G3DSA:3.40.50.720 3 270 6.8E-66 T 12-10-2018 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Gene3D G3DSA:2.60.40.10 1 120 7.2E-42 T 12-10-2018 IPR013783 Immunoglobulin-like fold THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 106 4.5E-21 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Gene3D G3DSA:3.20.20.80 123 521 3.2E-158 T 12-10-2018 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 SMART SM00642 149 500 1.1E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Pfam PF00128 Alpha amylase, catalytic domain 177 250 3.9E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 3 625 44.075 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 11 623 2.5E-268 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Gene3D G3DSA:2.60.40.1180 522 625 2.8E-40 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 PIRSF PIRSF000463 1 629 2.3E-274 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 SUPERFAMILY SSF51011 522 624 1.53E-37 T 12-10-2018 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 SUPERFAMILY SSF81296 36 111 1.39E-10 T 12-10-2018 IPR014756 Immunoglobulin E-set THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 527 624 1.3E-23 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THERU_01880 003cfd5f953d0fad76545d0577dd5435 632 SUPERFAMILY SSF51445 72 515 2.88E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily THERU_00525 c3fcdd974810562452a655b2a83ecc40 399 Gene3D G3DSA:3.30.300.10 26 155 2.4E-153 T 12-10-2018 THERU_00525 c3fcdd974810562452a655b2a83ecc40 399 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 2 393 2.1E-163 T 12-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 THERU_00525 c3fcdd974810562452a655b2a83ecc40 399 Gene3D G3DSA:3.30.300.340 14 282 2.4E-153 T 12-10-2018 THERU_00525 c3fcdd974810562452a655b2a83ecc40 399 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 2 385 2.0E-150 T 12-10-2018 THERU_00525 c3fcdd974810562452a655b2a83ecc40 399 Gene3D G3DSA:3.30.300.280 13 389 2.4E-153 T 12-10-2018 THERU_08450 299b1354b9a7c962e1e4fd0f8f422dcf 271 Gene3D G3DSA:3.40.50.1980 19 157 2.6E-29 T 12-10-2018 THERU_08450 299b1354b9a7c962e1e4fd0f8f422dcf 271 SUPERFAMILY SSF53807 21 268 4.71E-58 T 12-10-2018 THERU_08450 299b1354b9a7c962e1e4fd0f8f422dcf 271 Pfam PF01297 Zinc-uptake complex component A periplasmic 21 265 3.0E-55 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THERU_08450 299b1354b9a7c962e1e4fd0f8f422dcf 271 Gene3D G3DSA:3.40.50.1980 160 270 3.9E-23 T 12-10-2018 THERU_06715 3a0a264aa4792d5a8940c366c9b90106 200 Gene3D G3DSA:1.10.510.10 2 157 2.5E-7 T 12-10-2018 THERU_06715 3a0a264aa4792d5a8940c366c9b90106 200 SUPERFAMILY SSF56112 9 148 1.46E-17 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 Gene3D G3DSA:1.10.287.610 103 150 2.1E-88 T 12-10-2018 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.3E-38 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.529 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.2E-103 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 SUPERFAMILY SSF52313 6 232 9.16E-94 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 Pfam PF00318 Ribosomal protein S2 9 224 1.3E-92 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05630 8ab981e90faa71d28f2b24a3d4c2c599 275 Gene3D G3DSA:3.40.50.10490 8 219 2.1E-88 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 559 776 5.1E-31 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 49 291 1.1E-51 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Gene3D G3DSA:3.30.460.100 567 782 8.5E-39 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Gene3D G3DSA:3.30.460.100 56 295 1.5E-59 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 SUPERFAMILY SSF81593 303 448 7.14E-27 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 SUPERFAMILY SSF81301 31 301 5.63E-61 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 SUPERFAMILY SSF81593 790 923 1.49E-15 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Gene3D G3DSA:1.20.120.330 785 925 3.9E-15 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Gene3D G3DSA:1.20.120.330 300 453 2.3E-37 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 SUPERFAMILY SSF81301 535 783 3.43E-46 T 12-10-2018 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Pfam PF08335 GlnD PII-uridylyltransferase 314 447 5.4E-28 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THERU_04190 f3b24f850ec707bff6d4afeeca3e2727 925 Pfam PF08335 GlnD PII-uridylyltransferase 802 921 3.9E-7 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THERU_08345 e522d82f1a142734c342e16b23c35830 164 PRINTS PR01100 Shikimate kinase family signature 97 114 1.0E-23 T 12-10-2018 THERU_08345 e522d82f1a142734c342e16b23c35830 164 PRINTS PR01100 Shikimate kinase family signature 76 85 1.0E-23 T 12-10-2018 THERU_08345 e522d82f1a142734c342e16b23c35830 164 PRINTS PR01100 Shikimate kinase family signature 6 21 1.0E-23 T 12-10-2018 THERU_08345 e522d82f1a142734c342e16b23c35830 164 PRINTS PR01100 Shikimate kinase family signature 30 43 1.0E-23 T 12-10-2018 THERU_08345 e522d82f1a142734c342e16b23c35830 164 PRINTS PR01100 Shikimate kinase family signature 58 66 1.0E-23 T 12-10-2018 THERU_08345 e522d82f1a142734c342e16b23c35830 164 SUPERFAMILY SSF52540 5 162 3.34E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08345 e522d82f1a142734c342e16b23c35830 164 Pfam PF01202 Shikimate kinase 12 163 1.2E-44 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THERU_08345 e522d82f1a142734c342e16b23c35830 164 Hamap MF_00109 Shikimate kinase [aroK]. 3 164 25.414 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THERU_08345 e522d82f1a142734c342e16b23c35830 164 ProSitePatterns PS01128 Shikimate kinase signature. 59 84 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THERU_08345 e522d82f1a142734c342e16b23c35830 164 Gene3D G3DSA:3.40.50.300 4 164 9.0E-54 T 12-10-2018 THERU_07880 a17dee77af8e456c2704f76640cb5d4c 112 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 9 104 19.474 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_07880 a17dee77af8e456c2704f76640cb5d4c 112 SUPERFAMILY SSF54995 8 104 7.98E-31 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07880 a17dee77af8e456c2704f76640cb5d4c 112 Pfam PF01250 Ribosomal protein S6 11 101 5.0E-25 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07880 a17dee77af8e456c2704f76640cb5d4c 112 Gene3D G3DSA:3.30.70.60 3 111 1.2E-31 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THERU_07880 a17dee77af8e456c2704f76640cb5d4c 112 TIGRFAM TIGR00166 S6: ribosomal protein bS6 9 103 8.1E-24 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 Gene3D G3DSA:3.20.20.70 3 216 2.1E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 PIRSF PIRSF001461 1 221 2.3E-98 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 2.0E-96 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 1.7E-83 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THERU_00510 3c7a87a131f6086f563137b3bf288778 222 SUPERFAMILY SSF51366 3 215 1.41E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 SUPERFAMILY SSF64005 3 221 2.62E-83 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 171 188 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 4 225 2.2E-78 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 4 226 40.367 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 Pfam PF01255 Putative undecaprenyl diphosphate synthase 11 225 4.1E-78 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THERU_00835 bd617c07cc54e29fa6f562ac26f4f64c 228 Gene3D G3DSA:3.40.1180.10 1 227 1.1E-91 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 SUPERFAMILY SSF46992 3 86 8.76E-26 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 Pfam PF01649 Ribosomal protein S20 2 84 2.7E-25 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 Gene3D G3DSA:1.20.58.110 1 86 5.1E-26 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 23 91 3.0E-23 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.0E-21 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06165 f233a3412fc117637aa904f2b2a6dad9 95 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.564 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 SMART SM01240 8 474 0.0 T 12-10-2018 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 Pfam PF00571 CBS domain 152 206 1.1E-11 T 12-10-2018 IPR000644 CBS domain THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 Pfam PF00571 CBS domain 95 141 1.2E-13 T 12-10-2018 IPR000644 CBS domain THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 SMART SM00116 97 145 4.9E-13 T 12-10-2018 IPR000644 CBS domain THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 SMART SM00116 160 208 8.1E-11 T 12-10-2018 IPR000644 CBS domain THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 297 309 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 9 487 89.486 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 SUPERFAMILY SSF54631 66 205 1.41E-34 T 12-10-2018 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 474 4.5E-170 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 PIRSF PIRSF000130 1 488 4.4E-224 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 SUPERFAMILY SSF51412 5 478 1.44E-130 T 12-10-2018 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 Gene3D G3DSA:3.20.20.70 3 487 4.3E-229 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_01380 fab1d1d05e389cb568a6c5d9044fba52 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 9 456 1.1E-202 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 SUPERFAMILY SSF140490 328 420 5.23E-27 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 176 191 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 58 228 1.8E-51 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 335 415 2.1E-23 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Pfam PF10531 SLBB domain 254 289 2.0E-10 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 SMART SM00928 332 377 1.9E-19 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Gene3D G3DSA:1.20.1440.230 330 428 4.3E-26 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Gene3D G3DSA:3.40.50.11540 63 240 4.5E-80 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 Gene3D G3DSA:3.10.20.600 241 328 1.4E-19 T 12-10-2018 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 345 356 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 SUPERFAMILY SSF142019 15 243 2.75E-86 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02325 8a6ea70a67231945e1b61c0b5ff89e8e 429 SUPERFAMILY SSF142984 250 326 8.89E-14 T 12-10-2018 THERU_04255 c51db0c4122d6ef7a0f07c5999b04a84 309 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 144 277 4.0E-25 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THERU_04255 c51db0c4122d6ef7a0f07c5999b04a84 309 Gene3D G3DSA:3.40.50.2000 140 308 3.9E-34 T 12-10-2018 THERU_04255 c51db0c4122d6ef7a0f07c5999b04a84 309 Gene3D G3DSA:3.40.50.2000 2 136 3.2E-8 T 12-10-2018 THERU_04255 c51db0c4122d6ef7a0f07c5999b04a84 309 SUPERFAMILY SSF53756 3 304 8.64E-55 T 12-10-2018 THERU_07355 2886e905390d18d985aeac760f250c16 151 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 62 147 1.1E-36 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 THERU_07355 2886e905390d18d985aeac760f250c16 151 ProSitePatterns PS00323 Ribosomal protein S19 signature. 110 134 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 Pfam PF00203 Ribosomal protein S19 63 140 8.5E-34 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 PIRSF PIRSF002144 21 151 9.5E-30 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 57 146 23.514 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 Gene3D G3DSA:3.30.860.10 58 151 1.0E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 SUPERFAMILY SSF54570 60 141 1.44E-31 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 PRINTS PR00975 Ribosomal protein S19 family signature 90 109 5.5E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 PRINTS PR00975 Ribosomal protein S19 family signature 122 137 5.5E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07355 2886e905390d18d985aeac760f250c16 151 PRINTS PR00975 Ribosomal protein S19 family signature 110 122 5.5E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 SUPERFAMILY SSF50249 422 565 6.68E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Pfam PF01068 ATP dependent DNA ligase domain 219 413 3.9E-52 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Gene3D G3DSA:2.40.50.140 416 572 5.3E-48 T 12-10-2018 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 SUPERFAMILY SSF56091 213 413 1.82E-49 T 12-10-2018 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Gene3D G3DSA:3.30.470.30 214 415 5.3E-62 T 12-10-2018 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Hamap MF_00407 DNA ligase [lig]. 1 563 27.901 T 12-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Pfam PF04675 DNA ligase N terminus 2 167 2.0E-31 T 12-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Pfam PF04679 ATP dependent DNA ligase C terminal region 442 547 1.2E-18 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 563 7.0E-131 T 12-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 Gene3D G3DSA:1.10.3260.10 1 211 1.9E-55 T 12-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 THERU_02785 a3bb5048a1d5075956be93929c4e1e1d 572 SUPERFAMILY SSF117018 1 228 5.49E-49 T 12-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 906 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 922 22.167 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:1.10.8.280 286 385 1.4E-228 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 SUPERFAMILY SSF52540 14 407 2.07E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:3.30.190.20 131 243 1.4E-228 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:1.20.1580.10 91 476 1.4E-228 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:1.20.1580.10 675 812 8.9E-143 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 ProSitePatterns PS00211 ABC transporters family signature. 812 826 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 SMART SM00382 24 546 11.0 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 SMART SM00382 615 904 1.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 SUPERFAMILY SSF52540 596 891 2.48E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:3.40.50.300 596 918 8.9E-143 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Gene3D G3DSA:3.40.50.300 6 579 1.4E-228 T 12-10-2018 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 SUPERFAMILY SSF52540 10 553 1.39E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_03035 cee99e7cbec1d0f92eef79ecfb4cab33 935 Pfam PF00005 ABC transporter 606 842 3.5E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_01625 51b7c3cf54cffa130d9521e9cd4e0c14 640 SUPERFAMILY SSF63829 300 619 1.01E-9 T 12-10-2018 THERU_01625 51b7c3cf54cffa130d9521e9cd4e0c14 640 Pfam PF05787 Bacterial protein of unknown function (DUF839) 54 605 4.9E-162 T 12-10-2018 IPR008557 Protein of unknown function DUF839 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 Pfam PF00809 Pterin binding enzyme 127 374 1.4E-86 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 160 173 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 126 141 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 126 388 1.2E-101 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 Gene3D G3DSA:3.20.20.20 121 393 2.9E-105 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_08165 41dfb08018318f8f6a17d060ff09de26 395 SUPERFAMILY SSF51717 124 390 1.57E-95 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_03925 40b384d57cab62685434e25065627729 454 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THERU_03925 40b384d57cab62685434e25065627729 454 TIGRFAM TIGR04038 tatD_link_rSAM: radical SAM protein, TatD family-associated 259 451 1.3E-79 T 12-10-2018 IPR023821 Radical SAM, TatD-associated THERU_03925 40b384d57cab62685434e25065627729 454 Pfam PF13394 4Fe-4S single cluster domain 271 376 3.0E-8 T 12-10-2018 THERU_03925 40b384d57cab62685434e25065627729 454 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 185 201 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THERU_03925 40b384d57cab62685434e25065627729 454 Gene3D G3DSA:3.20.20.140 1 252 8.4E-90 T 12-10-2018 THERU_03925 40b384d57cab62685434e25065627729 454 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 120 130 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THERU_03925 40b384d57cab62685434e25065627729 454 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 250 1.0E-88 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 THERU_03925 40b384d57cab62685434e25065627729 454 Gene3D G3DSA:3.20.20.70 257 454 5.0E-32 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03925 40b384d57cab62685434e25065627729 454 Pfam PF04055 Radical SAM superfamily 270 439 6.9E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_03925 40b384d57cab62685434e25065627729 454 Pfam PF01026 TatD related DNase 2 250 7.5E-78 T 12-10-2018 IPR001130 TatD family GO:0016788 THERU_03925 40b384d57cab62685434e25065627729 454 SUPERFAMILY SSF51556 1 252 6.59E-81 T 12-10-2018 IPR032466 Metal-dependent hydrolase THERU_03925 40b384d57cab62685434e25065627729 454 SUPERFAMILY SSF102114 267 439 6.02E-36 T 12-10-2018 THERU_07140 9ee1384b33b22dda88fa2923c63a1b9a 613 Pfam PF13519 von Willebrand factor type A domain 437 542 4.0E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A THERU_07140 9ee1384b33b22dda88fa2923c63a1b9a 613 SUPERFAMILY SSF53300 435 599 9.05E-18 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THERU_07140 9ee1384b33b22dda88fa2923c63a1b9a 613 SMART SM00327 432 606 2.1E-17 T 12-10-2018 IPR002035 von Willebrand factor, type A THERU_07140 9ee1384b33b22dda88fa2923c63a1b9a 613 Gene3D G3DSA:3.40.50.410 428 606 2.2E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 SUPERFAMILY SSF48452 117 252 2.53E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 Pfam PF13181 Tetratricopeptide repeat 332 361 0.012 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 SMART SM00028 198 231 1.2E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 SMART SM00028 332 365 0.016 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 SMART SM00028 118 151 0.28 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 Pfam PF00515 Tetratricopeptide repeat 199 225 8.3E-8 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 SUPERFAMILY SSF48452 267 366 3.42E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 Gene3D G3DSA:1.25.40.10 107 257 6.1E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04945 d6480168c1e91f5a5c02437f139a372c 393 Gene3D G3DSA:1.25.40.10 261 387 2.5E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 46 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 SUPERFAMILY SSF56112 9 263 1.62E-64 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 Gene3D G3DSA:1.10.510.10 5 269 6.2E-61 T 12-10-2018 THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 SMART SM00220 14 265 3.1E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 Pfam PF00069 Protein kinase domain 14 262 1.1E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THERU_01035 9e3fe15bcb155ad36ede5ba2883795e7 271 PIRSF PIRSF000654 13 266 3.6E-21 T 12-10-2018 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Pfam PF00925 GTP cyclohydrolase II 214 379 7.9E-74 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 214 403 5.9E-79 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 6 204 1.8E-80 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Gene3D G3DSA:3.90.870.10 1 210 1.5E-93 T 12-10-2018 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 SUPERFAMILY SSF142695 210 381 1.44E-71 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 4 208 41.112 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 PIRSF PIRSF001259 4 403 8.6E-186 T 12-10-2018 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 203 4.2E-88 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Gene3D G3DSA:3.40.50.10990 211 383 1.9E-75 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 403 40.198 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 SUPERFAMILY SSF55821 6 211 3.66E-89 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THERU_08475 2433c2b4640b41f53e65dbab684fa837 403 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 5 401 57.433 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 SUPERFAMILY SSF48452 23 139 5.52E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 Gene3D G3DSA:1.25.40.10 16 143 1.8E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 Pfam PF13181 Tetratricopeptide repeat 98 128 6.3E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 SMART SM00028 64 97 2.1E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 SMART SM00028 98 130 0.23 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 SMART SM00028 30 63 2.8E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06730 87d0f39d185db927d0815d7a7f2f6024 143 Pfam PF13432 Tetratricopeptide repeat 35 97 7.1E-11 T 12-10-2018 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 SUPERFAMILY SSF54782 214 301 7.85E-25 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 SUPERFAMILY SSF53850 3 212 1.78E-79 T 12-10-2018 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 291 40.035 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PRINTS PR00151 Porphobilinogen deaminase signature 224 241 1.1E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PRINTS PR00151 Porphobilinogen deaminase signature 120 137 1.1E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PRINTS PR00151 Porphobilinogen deaminase signature 41 61 1.1E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PRINTS PR00151 Porphobilinogen deaminase signature 139 156 1.1E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 1.1E-50 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Gene3D G3DSA:3.40.190.10 4 204 1.3E-83 T 12-10-2018 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 291 9.4E-113 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 289 8.7E-21 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Gene3D G3DSA:3.40.190.10 99 196 1.3E-83 T 12-10-2018 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 207 7.9E-80 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 Gene3D G3DSA:3.30.160.40 215 300 7.0E-25 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 225 241 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_02295 5c12a88181196cfe77f3037f9d4dffb2 303 PIRSF PIRSF001438 1 302 7.6E-121 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 Gene3D G3DSA:3.30.1550.10 2 72 7.9E-33 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.621 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 5.8E-27 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 SUPERFAMILY SSF46906 68 141 2.49E-28 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 5.0E-15 T 12-10-2018 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 9.3E-27 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 2.8E-67 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 Gene3D G3DSA:1.10.10.2720 73 145 2.3E-31 T 12-10-2018 THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 SUPERFAMILY SSF54747 3 73 3.4E-29 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily THERU_07275 1e702c6ecad6df0a4e471c6f724f72f5 145 SMART SM00649 9 141 4.9E-86 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 PRINTS PR00625 DnaJ domain signature 9 27 4.6E-33 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 PRINTS PR00625 DnaJ domain signature 43 63 4.6E-33 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 PRINTS PR00625 DnaJ domain signature 27 42 4.6E-33 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 PRINTS PR00625 DnaJ domain signature 63 82 4.6E-33 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 SUPERFAMILY SSF49493 120 269 5.76E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Pfam PF00226 DnaJ domain 7 68 6.5E-30 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Gene3D G3DSA:2.60.260.20 260 366 3.2E-27 T 12-10-2018 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Pfam PF00684 DnaJ central domain 154 213 4.5E-11 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 SUPERFAMILY SSF49493 265 342 1.44E-23 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Pfam PF01556 DnaJ C terminal domain 127 340 5.0E-40 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 48 67 - T 12-10-2018 IPR018253 DnaJ domain, conserved site THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 7 342 4.5E-121 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Gene3D G3DSA:1.10.287.110 3 117 9.6E-40 T 12-10-2018 IPR036869 Chaperone J-domain superfamily THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 SMART SM00271 6 63 2.4E-34 T 12-10-2018 IPR001623 DnaJ domain THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Gene3D G3DSA:2.10.230.10 154 213 5.2E-34 T 12-10-2018 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 SUPERFAMILY SSF46565 3 96 7.33E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Gene3D G3DSA:2.60.260.20 124 255 5.2E-34 T 12-10-2018 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 4 377 35.866 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THERU_00370 2fed04f6cd31df0b0bf616d1b0c7f2eb 377 SUPERFAMILY SSF57938 141 217 1.31E-16 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 4 129 7.7E-57 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 84 95 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 Pfam PF00252 Ribosomal protein L16p/L10e 6 134 2.9E-45 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 PRINTS PR00060 Ribosomal protein L16 signature 90 119 4.9E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 PRINTS PR00060 Ribosomal protein L16 signature 44 55 4.9E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 PRINTS PR00060 Ribosomal protein L16 signature 26 38 4.9E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 PRINTS PR00060 Ribosomal protein L16 signature 60 89 4.9E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 3 136 36.24 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 SUPERFAMILY SSF54686 4 137 2.09E-51 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_07370 f1098b4a6ace1edf13be67566a49080a 142 Gene3D G3DSA:3.90.1170.10 3 139 7.6E-52 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_02010 7352f7a372df22dfb7e94c27b9f1caba 694 Pfam PF07715 TonB-dependent Receptor Plug Domain 36 146 6.6E-25 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain THERU_02010 7352f7a372df22dfb7e94c27b9f1caba 694 Gene3D G3DSA:2.170.130.10 17 157 9.6E-36 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THERU_02010 7352f7a372df22dfb7e94c27b9f1caba 694 Gene3D G3DSA:2.40.170.20 162 694 1.7E-76 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THERU_02010 7352f7a372df22dfb7e94c27b9f1caba 694 SUPERFAMILY SSF56935 20 694 5.29E-124 T 12-10-2018 THERU_02010 7352f7a372df22dfb7e94c27b9f1caba 694 Pfam PF00593 TonB dependent receptor 175 693 1.9E-45 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Gene3D G3DSA:3.40.50.12780 11 406 3.8E-101 T 12-10-2018 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 SUPERFAMILY SSF56801 17 522 1.44E-122 T 12-10-2018 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Pfam PF00501 AMP-binding enzyme 17 413 7.0E-101 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Pfam PF01553 Acyltransferase 651 777 1.2E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 12-10-2018 IPR020845 AMP-binding, conserved site THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 SMART SM00563 664 780 2.6E-32 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 SUPERFAMILY SSF47336 538 604 5.37E-12 T 12-10-2018 IPR036736 ACP-like superfamily THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Gene3D G3DSA:1.10.1200.10 539 614 9.0E-13 T 12-10-2018 IPR036736 ACP-like superfamily THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Pfam PF00550 Phosphopantetheine attachment site 548 601 8.1E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 Gene3D G3DSA:3.30.300.30 411 537 1.5E-7 T 12-10-2018 THERU_01895 bb2aef6730467f37e2df774cef7781b3 827 SUPERFAMILY SSF69593 627 826 2.35E-37 T 12-10-2018 THERU_05645 93f2c8e1a1bd22a84b2e5f4540f5f65a 78 Gene3D G3DSA:3.30.1200.10 1 78 9.5E-20 T 12-10-2018 IPR036591 YggU-like superfamily THERU_05645 93f2c8e1a1bd22a84b2e5f4540f5f65a 78 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 2 71 2.6E-19 T 12-10-2018 IPR003746 Protein of unknown function DUF167 THERU_05645 93f2c8e1a1bd22a84b2e5f4540f5f65a 78 Hamap MF_00634 UPF0235 protein YggU [yggU]. 1 78 13.061 T 12-10-2018 IPR003746 Protein of unknown function DUF167 THERU_05645 93f2c8e1a1bd22a84b2e5f4540f5f65a 78 SUPERFAMILY SSF69786 2 74 5.23E-18 T 12-10-2018 IPR036591 YggU-like superfamily THERU_05645 93f2c8e1a1bd22a84b2e5f4540f5f65a 78 SMART SM01152 1 73 2.8E-16 T 12-10-2018 IPR003746 Protein of unknown function DUF167 THERU_05985 d194877ee7c3e2e9b63e4098d737075b 230 Gene3D G3DSA:3.20.20.70 1 230 5.6E-71 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05985 d194877ee7c3e2e9b63e4098d737075b 230 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 230 30.208 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THERU_05985 d194877ee7c3e2e9b63e4098d737075b 230 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 1 228 4.0E-75 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THERU_05985 d194877ee7c3e2e9b63e4098d737075b 230 SUPERFAMILY SSF51366 1 230 8.75E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_05985 d194877ee7c3e2e9b63e4098d737075b 230 Pfam PF00977 Histidine biosynthesis protein 1 224 3.1E-64 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 114 749 1.9E-226 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Pfam PF00270 DEAD/DEAH box helicase 355 516 2.1E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Gene3D G3DSA:3.40.50.300 297 533 4.6E-87 T 12-10-2018 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Pfam PF17191 RecG wedge domain 97 235 1.2E-10 T 12-10-2018 IPR033454 RecG, wedge domain THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Gene3D G3DSA:3.40.50.300 541 713 1.1E-52 T 12-10-2018 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SUPERFAMILY SSF50249 92 260 2.06E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SUPERFAMILY SSF52540 535 742 8.27E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SUPERFAMILY SSF52540 266 535 1.7E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Gene3D G3DSA:2.40.50.140 132 226 1.8E-7 T 12-10-2018 THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SMART SM00490 420 488 0.93 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SMART SM00490 588 670 4.5E-18 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_00055 1da59554deee808aa3c92240ac7af01e 782 SMART SM00487 350 542 1.5E-35 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_00055 1da59554deee808aa3c92240ac7af01e 782 Pfam PF00271 Helicase conserved C-terminal domain 553 669 6.0E-17 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Gene3D G3DSA:3.50.30.10 365 475 2.2E-40 T 12-10-2018 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 487 844 8.6E-64 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 424 435 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Pfam PF00391 PEP-utilising enzyme, mobile domain 393 465 2.5E-26 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 348 1.4E-116 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 845 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 SUPERFAMILY SSF51621 472 848 4.45E-98 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Gene3D G3DSA:3.30.470.20 196 361 7.8E-53 T 12-10-2018 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 SUPERFAMILY SSF56059 2 395 7.77E-100 T 12-10-2018 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 Gene3D G3DSA:3.30.1490.20 1 195 2.0E-69 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 PIRSF PIRSF000854 1 559 3.7E-234 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 PIRSF PIRSF000854 577 850 6.2E-137 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 SUPERFAMILY SSF52009 362 477 5.23E-33 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 THERU_05300 193b7dd5f5e7f8783dd920f0c8cbdc14 853 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 750 768 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THERU_04660 218e881830c2cc445f6af0ef0df0c1d4 256 SUPERFAMILY SSF161098 61 247 3.4E-28 T 12-10-2018 IPR035906 MetI-like superfamily THERU_04660 218e881830c2cc445f6af0ef0df0c1d4 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 255 2.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_04660 218e881830c2cc445f6af0ef0df0c1d4 256 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 51 250 4.9E-69 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 THERU_04660 218e881830c2cc445f6af0ef0df0c1d4 256 Gene3D G3DSA:1.10.3720.10 63 255 1.8E-21 T 12-10-2018 IPR035906 MetI-like superfamily THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 SMART SM00382 58 338 4.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 10 449 43.557 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 Pfam PF07724 AAA domain (Cdc48 subfamily) 61 123 2.6E-6 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 Pfam PF07724 AAA domain (Cdc48 subfamily) 195 335 2.9E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 SMART SM01086 341 430 1.1E-23 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 SUPERFAMILY SSF52540 12 447 2.23E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 341 411 1.9E-6 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 13 449 8.7E-193 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THERU_04200 63361fdc1a97549ef46ddaa03e5aa54e 449 Gene3D G3DSA:1.10.8.60 341 446 4.2E-41 T 12-10-2018 THERU_07755 18a7c3359261f8e403e858eadc5beeb8 169 Hamap MF_00269 Thiol peroxidase [tpx]. 4 166 34.598 T 12-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 THERU_07755 18a7c3359261f8e403e858eadc5beeb8 169 ProSitePatterns PS01265 Tpx family signature. 84 95 - T 12-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 THERU_07755 18a7c3359261f8e403e858eadc5beeb8 169 Pfam PF08534 Redoxin 20 161 6.6E-20 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THERU_07755 18a7c3359261f8e403e858eadc5beeb8 169 Gene3D G3DSA:3.40.30.10 1 167 2.0E-42 T 12-10-2018 THERU_07755 18a7c3359261f8e403e858eadc5beeb8 169 SUPERFAMILY SSF52833 4 163 4.19E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_03395 102edc23af10cc0c73af273f6e956677 577 SMART SM00483 2 319 3.7E-31 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Gene3D G3DSA:3.30.210.10 264 329 8.4E-22 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily THERU_03395 102edc23af10cc0c73af273f6e956677 577 SUPERFAMILY SSF89550 342 574 2.09E-50 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THERU_03395 102edc23af10cc0c73af273f6e956677 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 301 318 7.6E-10 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_03395 102edc23af10cc0c73af273f6e956677 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 185 204 7.6E-10 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_03395 102edc23af10cc0c73af273f6e956677 577 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 7.6E-10 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Gene3D G3DSA:1.10.150.20 87 154 1.4E-15 T 12-10-2018 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Pfam PF02811 PHP domain 344 451 2.2E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Pfam PF14520 Helix-hairpin-helix domain 93 147 1.4E-7 T 12-10-2018 THERU_03395 102edc23af10cc0c73af273f6e956677 577 PIRSF PIRSF005047 2 574 8.1E-219 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_03395 102edc23af10cc0c73af273f6e956677 577 SMART SM00278 52 71 36.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THERU_03395 102edc23af10cc0c73af273f6e956677 577 SMART SM00278 92 111 6.7 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THERU_03395 102edc23af10cc0c73af273f6e956677 577 SUPERFAMILY SSF81301 156 319 1.64E-39 T 12-10-2018 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Gene3D G3DSA:3.30.460.10 156 263 3.3E-26 T 12-10-2018 THERU_03395 102edc23af10cc0c73af273f6e956677 577 Pfam PF14791 DNA polymerase beta thumb 257 319 5.3E-21 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain THERU_03395 102edc23af10cc0c73af273f6e956677 577 Gene3D G3DSA:1.10.150.110 1 86 3.1E-25 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily THERU_03395 102edc23af10cc0c73af273f6e956677 577 Pfam PF14716 Helix-hairpin-helix domain 4 72 4.3E-19 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain THERU_03395 102edc23af10cc0c73af273f6e956677 577 Gene3D G3DSA:3.20.20.140 331 576 4.9E-70 T 12-10-2018 THERU_03395 102edc23af10cc0c73af273f6e956677 577 SUPERFAMILY SSF47802 3 85 2.09E-19 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily THERU_03395 102edc23af10cc0c73af273f6e956677 577 SMART SM00481 343 424 3.1E-20 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THERU_05815 1cc85004279169a4ae40b5bcb134753b 172 Gene3D G3DSA:1.20.1220.20 5 167 2.4E-21 T 12-10-2018 THERU_05815 1cc85004279169a4ae40b5bcb134753b 172 Pfam PF01724 Domain of unknown function DUF29 11 165 8.9E-36 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 Gene3D G3DSA:3.30.70.141 1 140 2.9E-59 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 SUPERFAMILY SSF54919 2 139 3.4E-57 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 139 32.25 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 7.4E-29 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 7.4E-29 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 7.4E-29 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 115 134 7.4E-29 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 SMART SM00562 1 141 6.4E-81 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 Pfam PF00334 Nucleoside diphosphate kinase 2 138 3.3E-52 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THERU_03660 775a53d60ca9e575841efd1669358a9f 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 115 123 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 Pfam PF00815 Histidinol dehydrogenase 23 423 2.5E-166 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PIRSF PIRSF000099 1 426 3.3E-165 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 226 258 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 Gene3D G3DSA:3.40.50.1980 34 228 6.6E-125 T 12-10-2018 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 SUPERFAMILY SSF53720 24 423 1.02E-79 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 248 267 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 PRINTS PR00083 Histidinol dehydrogenase signature 226 247 6.0E-87 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 424 41.735 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 423 6.3E-160 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THERU_08110 ad035efd5efcaad6c3c10faeaf08f625 426 Gene3D G3DSA:3.40.50.1980 230 346 6.6E-125 T 12-10-2018 THERU_05450 cfe81e3982a2c3e068b4c34c29c0b67f 336 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 53 68 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05450 cfe81e3982a2c3e068b4c34c29c0b67f 336 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 336 24.067 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05450 cfe81e3982a2c3e068b4c34c29c0b67f 336 Pfam PF00146 NADH dehydrogenase 14 330 3.6E-114 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Gene3D G3DSA:3.30.160.270 394 501 2.9E-12 T 12-10-2018 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 43.879 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 SUPERFAMILY SSF110921 392 500 3.92E-26 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 498 2.6E-247 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Gene3D G3DSA:1.10.238.260 280 393 3.8E-43 T 12-10-2018 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 SMART SM00917 369 501 5.8E-37 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Gene3D G3DSA:3.20.20.70 1 276 2.9E-113 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 SUPERFAMILY SSF51569 1 291 5.86E-102 T 12-10-2018 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Pfam PF00682 HMGL-like 3 272 1.8E-102 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THERU_02720 82435c1321704a531d2c4b113833ff6e 519 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 500 1.3E-36 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 SUPERFAMILY SSF52922 270 383 4.19E-22 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 Gene3D G3DSA:3.40.50.920 270 378 5.5E-24 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 SUPERFAMILY SSF52518 18 242 4.17E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 31 254 3.2E-63 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 275 353 1.8E-19 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II THERU_06515 faec93bb97d0c9d8389552959f7d1510 389 Gene3D G3DSA:3.40.50.970 18 255 6.2E-53 T 12-10-2018 THERU_03780 78a7e6257e92d1f978ac060ca971f112 289 Gene3D G3DSA:3.40.50.300 4 230 5.1E-63 T 12-10-2018 THERU_03780 78a7e6257e92d1f978ac060ca971f112 289 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_03780 78a7e6257e92d1f978ac060ca971f112 289 SUPERFAMILY SSF52540 10 226 8.47E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03780 78a7e6257e92d1f978ac060ca971f112 289 Pfam PF00005 ABC transporter 20 160 1.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_03780 78a7e6257e92d1f978ac060ca971f112 289 SMART SM00382 27 210 1.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 4 419 8.1E-167 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 70 2.4E-6 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 Gene3D G3DSA:3.40.50.12240 1 422 9.1E-132 T 12-10-2018 THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 SMART SM00382 142 323 9.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 SUPERFAMILY SSF52540 79 345 8.49E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 339 3.7E-62 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03130 5d5eb91cf29d23fa5821ae95908ffdae 425 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 330 339 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 Hamap MF_01694 Biotin synthase [bioB]. 19 329 42.541 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 SUPERFAMILY SSF102114 19 311 1.44E-70 T 12-10-2018 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 Pfam PF04055 Radical SAM superfamily 69 226 2.3E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 PIRSF PIRSF001619 3 332 2.0E-125 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 Gene3D G3DSA:3.20.20.70 21 330 6.1E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 SMART SM00729 60 270 1.5E-39 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 238 326 3.6E-14 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 TIGRFAM TIGR00433 bioB: biotin synthase 32 326 2.7E-114 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THERU_06325 e63fac4a3af05a22765902671c5cc6dd 333 SMART SM00876 238 328 4.4E-29 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 Gene3D G3DSA:3.40.640.10 77 345 5.4E-147 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 439 45.447 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 PIRSF PIRSF006815 1 440 2.5E-162 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 Pfam PF02347 Glycine cleavage system P-protein 2 434 4.1E-149 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 SUPERFAMILY SSF53383 2 437 7.36E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02065 2b754c3e015fe9ff2fa32edb7600805c 451 Gene3D G3DSA:3.90.1150.10 66 436 5.4E-147 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 380 393 4.2E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 87 99 4.2E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 67 85 4.2E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 200 213 4.2E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 281 300 4.2E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01181 Diaminopimelate decarboxylase signature 85 102 3.1E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01181 Diaminopimelate decarboxylase signature 309 327 3.1E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01181 Diaminopimelate decarboxylase signature 174 183 3.1E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07655 a61abceaacf76f645a15009a12be6931 424 PRINTS PR01181 Diaminopimelate decarboxylase signature 390 412 3.1E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07655 a61abceaacf76f645a15009a12be6931 424 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 49 291 9.0E-68 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 27 423 44.789 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_07655 a61abceaacf76f645a15009a12be6931 424 Gene3D G3DSA:3.20.20.10 46 286 5.0E-163 T 12-10-2018 IPR029066 PLP-binding barrel THERU_07655 a61abceaacf76f645a15009a12be6931 424 Gene3D G3DSA:2.40.37.10 26 419 5.0E-163 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 42 380 2.3E-27 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 SUPERFAMILY SSF51419 38 293 1.44E-87 T 12-10-2018 IPR029066 PLP-binding barrel THERU_07655 a61abceaacf76f645a15009a12be6931 424 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 238 251 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site THERU_07655 a61abceaacf76f645a15009a12be6931 424 SUPERFAMILY SSF50621 266 420 6.7E-55 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_07655 a61abceaacf76f645a15009a12be6931 424 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 17 420 6.6E-172 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_05575 01d3942c65ad228b30feb09d00676727 223 SMART SM00862 143 217 1.1E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_05575 01d3942c65ad228b30feb09d00676727 223 SUPERFAMILY SSF46894 116 219 3.12E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THERU_05575 01d3942c65ad228b30feb09d00676727 223 SMART SM00448 1 111 1.7E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_05575 01d3942c65ad228b30feb09d00676727 223 Gene3D G3DSA:1.10.10.10 121 222 2.3E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_05575 01d3942c65ad228b30feb09d00676727 223 Gene3D G3DSA:3.40.50.2300 1 120 8.7E-40 T 12-10-2018 THERU_05575 01d3942c65ad228b30feb09d00676727 223 SUPERFAMILY SSF52172 1 126 2.28E-40 T 12-10-2018 IPR011006 CheY-like superfamily THERU_05575 01d3942c65ad228b30feb09d00676727 223 Pfam PF00072 Response regulator receiver domain 3 112 9.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_05575 01d3942c65ad228b30feb09d00676727 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 217 7.3E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 Gene3D G3DSA:1.20.200.10 96 351 7.3E-99 T 12-10-2018 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 Pfam PF00206 Lyase 10 289 6.7E-60 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 SUPERFAMILY SSF48557 4 431 4.87E-134 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00145 Argininosuccinate lyase family signature 219 243 3.3E-13 T 12-10-2018 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00145 Argininosuccinate lyase family signature 264 280 3.3E-13 T 12-10-2018 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 3.3E-13 T 12-10-2018 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 3.3E-13 T 12-10-2018 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 SMART SM00998 352 432 8.7E-28 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 Gene3D G3DSA:1.10.275.10 1 95 1.3E-27 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 353 431 4.2E-20 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 ProSitePatterns PS00163 Fumarate lyases signature. 264 273 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 5.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00149 Fumarate lyase superfamily signature 219 246 5.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 5.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 PRINTS PR00149 Fumarate lyase superfamily signature 264 280 5.5E-28 T 12-10-2018 IPR000362 Fumarate lyase family THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 431 3.7E-163 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_05375 ecbec487846fd151fd07c3bdeac97f8c 435 Gene3D G3DSA:1.10.40.30 352 434 2.1E-25 T 12-10-2018 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 SUPERFAMILY SSF53067 3 95 1.29E-10 T 12-10-2018 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 Gene3D G3DSA:3.30.420.490 98 207 6.4E-35 T 12-10-2018 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 Gene3D G3DSA:3.30.420.40 4 210 6.4E-35 T 12-10-2018 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 Hamap MF_01274 Type III pantothenate kinase [coaX]. 2 222 14.598 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 217 1.6E-40 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 SUPERFAMILY SSF53067 98 217 2.46E-20 T 12-10-2018 THERU_02955 fda9d1adf2b868a6bbf457d840df07ad 222 Pfam PF03309 Type III pantothenate kinase 3 178 5.0E-22 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 PIRSF PIRSF000726 2 61 8.6E-19 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 PIRSF PIRSF000726 60 409 1.0E-123 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 SUPERFAMILY SSF53633 5 243 2.09E-72 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Gene3D G3DSA:3.30.70.260 255 400 1.5E-54 T 12-10-2018 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Pfam PF13840 ACT domain 335 398 8.5E-14 T 12-10-2018 IPR027795 CASTOR, ACT domain THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Pfam PF00696 Amino acid kinase family 3 230 2.5E-47 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 SUPERFAMILY SSF55021 247 325 8.51E-17 T 12-10-2018 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 SUPERFAMILY SSF55021 327 405 1.88E-23 T 12-10-2018 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Gene3D G3DSA:3.30.70.260 260 337 1.5E-54 T 12-10-2018 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 402 1.1E-130 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Gene3D G3DSA:3.40.1160.10 2 254 4.0E-87 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 2.3E-124 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 Pfam PF01842 ACT domain 266 326 3.3E-11 T 12-10-2018 IPR002912 ACT domain THERU_03235 8809f8c5e24058949735d40c8d48ca1e 412 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 Gene3D G3DSA:3.30.750.44 54 319 2.9E-52 T 12-10-2018 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 Gene3D G3DSA:3.90.226.10 166 341 2.9E-52 T 12-10-2018 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 SUPERFAMILY SSF50156 83 167 6.05E-15 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 SMART SM00245 140 345 3.0E-14 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 SMART SM00228 84 151 1.1E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 Pfam PF13180 PDZ domain 95 158 6.2E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 Gene3D G3DSA:2.30.42.10 86 165 2.9E-52 T 12-10-2018 THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 SUPERFAMILY SSF52096 64 345 2.24E-40 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_01040 1a6cd24ca157fc57742a7606864961ec 369 Pfam PF03572 Peptidase family S41 180 342 1.5E-32 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THERU_06860 206d0af6a020660362b1bbfdfc06e69e 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 15 47 5.7E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THERU_06860 206d0af6a020660362b1bbfdfc06e69e 80 SUPERFAMILY SSF89447 3 47 1.69E-10 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily THERU_06860 206d0af6a020660362b1bbfdfc06e69e 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 6.6E-13 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THERU_06860 206d0af6a020660362b1bbfdfc06e69e 80 Gene3D G3DSA:2.10.260.10 1 43 3.3E-14 T 12-10-2018 THERU_06860 206d0af6a020660362b1bbfdfc06e69e 80 SMART SM00966 5 50 5.7E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THERU_02150 18e0659caaa16a2b8411547d4c56698f 170 Gene3D G3DSA:1.20.120.1760 3 163 9.2E-9 T 12-10-2018 THERU_02150 18e0659caaa16a2b8411547d4c56698f 170 PIRSF PIRSF000847 1 168 1.8E-30 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THERU_02150 18e0659caaa16a2b8411547d4c56698f 170 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 40 62 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_02150 18e0659caaa16a2b8411547d4c56698f 170 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 62 5.2E-17 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 Gene3D G3DSA:3.20.20.210 3 336 2.0E-118 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 3 334 39.594 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 6 331 1.5E-110 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 133 149 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 333 7.5E-101 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 19 28 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THERU_08070 9990a9934acef6f1e764d1c15f63302f 336 SUPERFAMILY SSF51726 5 334 5.1E-87 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_08010 f6054e4caacc9650138506829647739d 99 SUPERFAMILY SSF54909 22 98 1.21E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel THERU_08010 f6054e4caacc9650138506829647739d 99 Pfam PF01037 Lrp/AsnC ligand binding domain 28 98 6.9E-12 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THERU_08010 f6054e4caacc9650138506829647739d 99 Gene3D G3DSA:3.30.70.920 25 99 1.2E-18 T 12-10-2018 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 ProSitePatterns PS00605 ATP synthase c subunit signature. 59 80 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 Gene3D G3DSA:1.20.20.10 21 97 2.7E-25 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 39 95 4.9E-14 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 Pfam PF00137 ATP synthase subunit C 30 93 7.2E-18 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 PRINTS PR00124 ATP synthase C subunit signature 52 67 1.5E-17 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 PRINTS PR00124 ATP synthase C subunit signature 31 50 1.5E-17 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 PRINTS PR00124 ATP synthase C subunit signature 69 94 1.5E-17 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 Hamap MF_01396 ATP synthase subunit c [atpH]. 29 94 15.401 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_00895 2a4540c111a700641379cc06bc7c41fc 97 SUPERFAMILY SSF81333 23 95 2.88E-22 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily THERU_03495 95b733c27c5f86b2c461807a2646d3a8 160 Pfam PF03938 Outer membrane protein (OmpH-like) 6 157 1.3E-29 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 THERU_03495 95b733c27c5f86b2c461807a2646d3a8 160 SUPERFAMILY SSF111384 17 158 9.94E-25 T 12-10-2018 THERU_03495 95b733c27c5f86b2c461807a2646d3a8 160 Gene3D G3DSA:3.30.910.20 12 160 1.5E-27 T 12-10-2018 IPR024930 Skp domain superfamily THERU_03495 95b733c27c5f86b2c461807a2646d3a8 160 SMART SM00935 6 158 4.1E-31 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 Gene3D G3DSA:3.20.10.10 127 298 4.3E-53 T 12-10-2018 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 Gene3D G3DSA:3.30.470.10 1 124 3.7E-30 T 12-10-2018 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 5 302 4.1E-117 T 12-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 ProSitePatterns PS00770 Aminotransferases class-IV signature. 188 217 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 Pfam PF01063 Amino-transferase class IV 31 263 1.9E-43 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 THERU_07815 02dfe658d815f5c970c202ce6a45f544 305 SUPERFAMILY SSF56752 2 299 2.75E-85 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 2 138 1.6E-34 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 PIRSF PIRSF003078 1 154 1.6E-35 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 SUPERFAMILY SSF53335 2 130 2.9E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 1 156 14.769 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 Pfam PF02527 rRNA small subunit methyltransferase G 2 135 4.9E-35 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THERU_08380 4ac62faac0fd8333b563f97b47d3ded8 162 Gene3D G3DSA:3.40.50.150 1 161 2.6E-35 T 12-10-2018 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 SMART SM00845 321 469 5.1E-73 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 Gene3D G3DSA:1.10.150.380 290 408 1.7E-38 T 12-10-2018 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 SUPERFAMILY SSF55931 4 289 7.19E-127 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 Gene3D G3DSA:1.10.10.410 409 470 1.1E-25 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 Pfam PF02637 GatB domain 321 469 1.7E-53 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 Pfam PF02934 GatB/GatE catalytic domain 6 282 1.5E-120 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 SUPERFAMILY SSF89095 290 397 9.16E-31 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 137 151 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 470 40.381 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THERU_03685 19bdeee08fa064ec46dc8a52cd87f0b4 471 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 469 3.2E-185 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR00811 Bacterial general secretion pathway protein D signature 617 631 1.2E-15 T 12-10-2018 IPR001775 GspD/PilQ family THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR00811 Bacterial general secretion pathway protein D signature 459 483 1.2E-15 T 12-10-2018 IPR001775 GspD/PilQ family THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR00811 Bacterial general secretion pathway protein D signature 594 612 1.2E-15 T 12-10-2018 IPR001775 GspD/PilQ family THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR00811 Bacterial general secretion pathway protein D signature 383 393 1.2E-15 T 12-10-2018 IPR001775 GspD/PilQ family THERU_06790 b2b61276cb580634e53e374c2283978e 668 Gene3D G3DSA:3.30.1370.120 194 261 1.8E-9 T 12-10-2018 IPR038591 NolW-like superfamily THERU_06790 b2b61276cb580634e53e374c2283978e 668 Gene3D G3DSA:3.30.1370.120 36 188 2.4E-43 T 12-10-2018 IPR038591 NolW-like superfamily THERU_06790 b2b61276cb580634e53e374c2283978e 668 Pfam PF00263 Bacterial type II and III secretion system protein 464 629 5.0E-41 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 THERU_06790 b2b61276cb580634e53e374c2283978e 668 Pfam PF03958 Bacterial type II/III secretion system short domain 271 383 3.1E-14 T 12-10-2018 IPR005644 NolW-like THERU_06790 b2b61276cb580634e53e374c2283978e 668 Pfam PF03958 Bacterial type II/III secretion system short domain 133 191 1.9E-7 T 12-10-2018 IPR005644 NolW-like THERU_06790 b2b61276cb580634e53e374c2283978e 668 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 39 639 4.0E-145 T 12-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR01032 Gene IV protein signature 484 507 3.9E-8 T 12-10-2018 THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR01032 Gene IV protein signature 610 632 3.9E-8 T 12-10-2018 THERU_06790 b2b61276cb580634e53e374c2283978e 668 PRINTS PR01032 Gene IV protein signature 557 585 3.9E-8 T 12-10-2018 THERU_05720 0e28fd8aa132078e1d830ea0bd71e404 935 Pfam PF07728 AAA domain (dynein-related subfamily) 654 787 3.8E-26 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THERU_05720 0e28fd8aa132078e1d830ea0bd71e404 935 SUPERFAMILY SSF52540 641 919 3.84E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05720 0e28fd8aa132078e1d830ea0bd71e404 935 SUPERFAMILY SSF50998 46 305 1.8E-9 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THERU_05720 0e28fd8aa132078e1d830ea0bd71e404 935 Gene3D G3DSA:3.40.50.300 637 802 1.4E-23 T 12-10-2018 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 Pfam PF01568 Molydopterin dinucleotide binding domain 780 859 6.7E-15 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 60 1.5E-14 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 SUPERFAMILY SSF50692 767 929 4.75E-33 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 Gene3D G3DSA:3.40.50.740 7 602 1.7E-100 T 12-10-2018 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 SUPERFAMILY SSF53706 9 764 3.14E-143 T 12-10-2018 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 816 843 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 Gene3D G3DSA:2.40.40.20 757 916 1.7E-28 T 12-10-2018 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 SMART SM00926 9 63 1.7E-17 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06660 c32c88d08fbb8e167b4349930beac4dd 947 Pfam PF00384 Molybdopterin oxidoreductase 66 571 1.4E-29 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04040 eca1ddf65a6b55c105af0a8df7ea43ec 302 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 26 271 3.3E-10 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain THERU_04040 eca1ddf65a6b55c105af0a8df7ea43ec 302 SUPERFAMILY SSF52266 23 287 5.64E-20 T 12-10-2018 THERU_04035 7ddc79baca803e9400d684fe41f84902 90 Gene3D G3DSA:3.40.50.720 5 87 1.2E-11 T 12-10-2018 THERU_04035 7ddc79baca803e9400d684fe41f84902 90 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 14 46 3.7E-7 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_04035 7ddc79baca803e9400d684fe41f84902 90 SUPERFAMILY SSF51735 14 46 1.43E-8 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 SUPERFAMILY SSF53335 1 286 7.9E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 Gene3D G3DSA:3.40.50.150 2 282 1.8E-109 T 12-10-2018 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 2 286 37.458 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 SUPERFAMILY SSF81799 109 207 3.92E-36 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 Gene3D G3DSA:1.10.150.170 108 208 1.8E-109 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 PIRSF PIRSF004486 1 286 1.3E-107 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 Pfam PF01795 MraW methylase family 2 285 3.9E-110 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THERU_06575 58a598b62661cb884aee417d6a5dc3c3 286 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 285 2.0E-98 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THERU_00595 5601de2cfe957051eaa0137c35977727 189 Pfam PF01553 Acyltransferase 11 134 2.4E-29 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THERU_00595 5601de2cfe957051eaa0137c35977727 189 SUPERFAMILY SSF69593 7 186 7.59E-53 T 12-10-2018 THERU_00595 5601de2cfe957051eaa0137c35977727 189 SMART SM00563 25 137 2.7E-41 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THERU_00595 5601de2cfe957051eaa0137c35977727 189 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 10 134 8.7E-32 T 12-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 THERU_05725 6821f91c21e8e83597dcf918139c242a 94 Pfam PF03330 Lytic transglycolase 2 86 2.1E-19 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THERU_05725 6821f91c21e8e83597dcf918139c242a 94 SUPERFAMILY SSF50685 10 93 2.69E-13 T 12-10-2018 IPR036908 RlpA-like domain superfamily THERU_05725 6821f91c21e8e83597dcf918139c242a 94 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 1 92 2.9E-30 T 12-10-2018 IPR012997 Rare lipoprotein A THERU_05725 6821f91c21e8e83597dcf918139c242a 94 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 1 90 18.535 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THERU_05725 6821f91c21e8e83597dcf918139c242a 94 Gene3D G3DSA:2.40.40.10 1 90 5.1E-32 T 12-10-2018 IPR036908 RlpA-like domain superfamily THERU_04885 11ef313712476128a04e639d5b796d9e 331 SUPERFAMILY SSF55326 3 147 1.59E-32 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_04885 11ef313712476128a04e639d5b796d9e 331 Gene3D G3DSA:3.30.1330.10 8 149 8.8E-49 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_04885 11ef313712476128a04e639d5b796d9e 331 PIRSF PIRSF005644 1 331 1.8E-124 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE THERU_04885 11ef313712476128a04e639d5b796d9e 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 158 302 2.8E-27 T 12-10-2018 IPR010918 PurM-like, C-terminal domain THERU_04885 11ef313712476128a04e639d5b796d9e 331 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 3 331 1.7E-135 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE THERU_04885 11ef313712476128a04e639d5b796d9e 331 Gene3D G3DSA:3.90.650.10 151 331 1.1E-54 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_04885 11ef313712476128a04e639d5b796d9e 331 SUPERFAMILY SSF56042 153 326 2.09E-41 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_04885 11ef313712476128a04e639d5b796d9e 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 147 4.0E-18 T 12-10-2018 IPR016188 PurM-like, N-terminal domain THERU_07055 45353bbc9e65d4d2a771ee4915ec0711 352 SUPERFAMILY SSF56935 103 348 2.38E-13 T 12-10-2018 THERU_07055 45353bbc9e65d4d2a771ee4915ec0711 352 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 29 352 2.7E-67 T 12-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 305 312 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 SUPERFAMILY SSF55021 262 358 2.4E-31 T 12-10-2018 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 SUPERFAMILY SSF48600 3 95 8.09E-21 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Gene3D G3DSA:3.40.190.10 95 265 1.0E-59 T 12-10-2018 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Pfam PF01817 Chorismate mutase type II 8 89 3.1E-24 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Gene3D G3DSA:3.30.70.260 271 359 5.6E-34 T 12-10-2018 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 SMART SM00830 8 91 1.9E-29 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 PIRSF PIRSF001500 1 360 1.1E-137 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 SUPERFAMILY SSF53850 92 275 6.19E-61 T 12-10-2018 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 243 265 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Pfam PF00800 Prephenate dehydratase 93 269 4.5E-63 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Gene3D G3DSA:3.40.190.10 173 257 1.0E-59 T 12-10-2018 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Gene3D G3DSA:1.20.59.10 1 91 7.0E-28 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THERU_00665 59057e9d92243d0ee60eb2a770ae5017 363 Pfam PF01842 ACT domain 278 339 2.8E-8 T 12-10-2018 IPR002912 ACT domain THERU_00165 6483a7f8327e232918a874f621830a54 242 Pfam PF13534 4Fe-4S dicluster domain 44 101 2.9E-8 T 12-10-2018 THERU_00165 6483a7f8327e232918a874f621830a54 242 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_00165 6483a7f8327e232918a874f621830a54 242 SUPERFAMILY SSF46548 32 119 1.06E-13 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_00165 6483a7f8327e232918a874f621830a54 242 Gene3D G3DSA:1.10.1060.10 11 125 1.3E-5 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_04735 99e0af0ccb88749380b6fded73736d17 309 Pfam PF00850 Histone deacetylase domain 19 303 3.1E-84 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_04735 99e0af0ccb88749380b6fded73736d17 309 SUPERFAMILY SSF52768 1 308 3.36E-110 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily THERU_04735 99e0af0ccb88749380b6fded73736d17 309 Gene3D G3DSA:3.40.800.20 2 309 2.7E-109 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_04735 99e0af0ccb88749380b6fded73736d17 309 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 2.3E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_04735 99e0af0ccb88749380b6fded73736d17 309 PRINTS PR01270 Histone deacetylase superfamily signature 237 247 2.3E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_04735 99e0af0ccb88749380b6fded73736d17 309 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 2.3E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_03115 1412920d22766abf7023859211fe0bee 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THERU_03115 1412920d22766abf7023859211fe0bee 190 SUPERFAMILY SSF53178 2 186 1.57E-62 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 THERU_03115 1412920d22766abf7023859211fe0bee 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 179 34.481 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THERU_03115 1412920d22766abf7023859211fe0bee 190 Pfam PF01195 Peptidyl-tRNA hydrolase 4 183 3.9E-58 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THERU_03115 1412920d22766abf7023859211fe0bee 190 Gene3D G3DSA:3.40.50.1470 1 188 2.9E-67 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 THERU_03115 1412920d22766abf7023859211fe0bee 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 177 1.9E-60 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THERU_02225 d6568a0af12a02a571e1182c75557273 211 SUPERFAMILY SSF53271 44 209 1.19E-20 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_02225 d6568a0af12a02a571e1182c75557273 211 Gene3D G3DSA:3.40.50.2020 48 210 9.8E-13 T 12-10-2018 THERU_02225 d6568a0af12a02a571e1182c75557273 211 Pfam PF00156 Phosphoribosyl transferase domain 166 203 3.0E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 Gene3D G3DSA:2.60.120.10 5 141 2.1E-31 T 12-10-2018 IPR014710 RmlC-like jelly roll fold THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 Gene3D G3DSA:1.10.10.10 142 208 2.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 SUPERFAMILY SSF46785 147 206 1.32E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 164 180 1.4E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 180 195 1.4E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 SUPERFAMILY SSF51206 9 142 2.23E-24 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 SMART SM00419 158 206 1.4E-10 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 Pfam PF00027 Cyclic nucleotide-binding domain 28 117 1.9E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain THERU_02140 e30111c6d0753a7c4db83ab1dbbe9a5e 209 Pfam PF13545 Crp-like helix-turn-helix domain 150 207 7.7E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 Gene3D G3DSA:2.170.230.10 87 149 5.2E-56 T 12-10-2018 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 150 169 1.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 1.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 88 1.0E-22 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 Pfam PF00717 Peptidase S24-like 31 100 2.8E-21 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 Gene3D G3DSA:2.10.109.10 22 189 5.2E-56 T 12-10-2018 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 ProSitePatterns PS00760 Signal peptidases I lysine active site. 78 90 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 SUPERFAMILY SSF51306 22 190 5.23E-62 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 Pfam PF10502 Signal peptidase, peptidase S26 149 184 3.4E-6 T 12-10-2018 IPR019533 Peptidase S26 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 ProSitePatterns PS00761 Signal peptidases I signature 3. 155 168 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 THERU_01570 31d31230a9cffa31d48275d1f16c8ada 227 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 7 189 5.8E-54 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THERU_04595 2cf70dade2ff965d5740fce193a7df00 276 SMART SM00267 94 260 6.9E-50 T 12-10-2018 IPR000160 GGDEF domain THERU_04595 2cf70dade2ff965d5740fce193a7df00 276 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 103 259 4.2E-45 T 12-10-2018 IPR000160 GGDEF domain THERU_04595 2cf70dade2ff965d5740fce193a7df00 276 SUPERFAMILY SSF55073 109 259 6.75E-45 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_04595 2cf70dade2ff965d5740fce193a7df00 276 Gene3D G3DSA:3.30.70.270 101 264 7.7E-49 T 12-10-2018 THERU_04595 2cf70dade2ff965d5740fce193a7df00 276 Pfam PF00990 Diguanylate cyclase, GGDEF domain 105 255 7.4E-42 T 12-10-2018 IPR000160 GGDEF domain THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Pfam PF01103 Surface antigen 599 851 3.6E-26 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Pfam PF07244 Surface antigen variable number repeat 290 354 1.4E-6 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Pfam PF07244 Surface antigen variable number repeat 80 155 3.5E-7 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Gene3D G3DSA:3.10.20.310 78 155 7.1E-10 T 12-10-2018 THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Gene3D G3DSA:3.10.20.310 277 357 2.5E-6 T 12-10-2018 THERU_07765 5f9f83406191c5f0e2f2d9ec1e520ccc 869 Gene3D G3DSA:2.40.160.50 575 867 1.0E-40 T 12-10-2018 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 Gene3D G3DSA:1.10.10.60 1 43 3.7E-15 T 12-10-2018 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 Gene3D G3DSA:1.10.357.10 44 193 3.4E-41 T 12-10-2018 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 SUPERFAMILY SSF48498 77 190 8.38E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 SUPERFAMILY SSF46689 4 79 2.57E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 4.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 4.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_00475 e39815a7b50fb9361e60b95e2f383659 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 4.9E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_07680 873bbc1fd5d3bb85fa3af847acd62afe 185 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 THERU_07680 873bbc1fd5d3bb85fa3af847acd62afe 185 Pfam PF00258 Flavodoxin 6 130 5.6E-11 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THERU_07680 873bbc1fd5d3bb85fa3af847acd62afe 185 SUPERFAMILY SSF52218 1 177 2.88E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily THERU_07680 873bbc1fd5d3bb85fa3af847acd62afe 185 Gene3D G3DSA:3.40.50.360 1 185 1.3E-60 T 12-10-2018 IPR029039 Flavoprotein-like superfamily THERU_02275 572894093d66a7539c564c65a8a11d65 63 Pfam PF09360 Iron-binding zinc finger CDGSH type 7 40 1.6E-13 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THERU_02275 572894093d66a7539c564c65a8a11d65 63 Gene3D G3DSA:3.40.5.90 3 55 1.0E-18 T 12-10-2018 THERU_02275 572894093d66a7539c564c65a8a11d65 63 SMART SM00704 9 45 3.7E-9 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 6 451 41.242 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Pfam PF08245 Mur ligase middle domain 111 289 2.7E-34 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Gene3D G3DSA:3.40.50.720 7 93 7.8E-34 T 12-10-2018 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Gene3D G3DSA:3.90.190.20 308 451 5.4E-49 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Pfam PF01225 Mur ligase family, catalytic domain 9 104 2.3E-27 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Gene3D G3DSA:3.40.1190.10 95 307 1.2E-79 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 393 2.5E-23 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 SUPERFAMILY SSF53623 93 308 1.83E-69 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 8 445 5.2E-164 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 SUPERFAMILY SSF53244 311 446 5.13E-39 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_05245 4ffc99e1de38922df0385d79c4207965 452 SUPERFAMILY SSF51984 6 93 1.44E-30 T 12-10-2018 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 368 43.25 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 368 2.4E-144 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 SUPERFAMILY SSF81271 284 365 4.36E-35 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Gene3D G3DSA:3.10.20.30 49 366 8.3E-147 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.1E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 4.8E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.8E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 4.8E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 4.8E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 PIRSF PIRSF006641 1 368 1.3E-155 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Gene3D G3DSA:3.40.50.300 4 283 8.3E-147 T 12-10-2018 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 SUPERFAMILY SSF52540 4 306 1.8E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Pfam PF06071 Protein of unknown function (DUF933) 284 367 2.3E-39 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 THERU_04575 00de07d05b6366ecff34e93defb681ef 368 Gene3D G3DSA:1.10.150.300 114 204 8.3E-147 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 173 193 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 211 228 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 71 83 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 149 170 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 193 210 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 105 124 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 PRINTS PR01166 Cytochrome c oxidase subunit II signature 83 103 4.3E-18 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 Gene3D G3DSA:1.10.287.90 14 101 1.0E-19 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 SUPERFAMILY SSF49503 104 247 5.5E-38 T 12-10-2018 IPR008972 Cupredoxin THERU_05615 d87ce6f41191acd278c123b4059bf029 254 SUPERFAMILY SSF81464 13 98 8.01E-16 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 Gene3D G3DSA:2.60.40.2600 105 252 8.2E-41 T 12-10-2018 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 29 238 2.3E-50 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 111 229 4.1E-20 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 174 222 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05615 d87ce6f41191acd278c123b4059bf029 254 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 25 96 2.0E-10 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 SUPERFAMILY SSF55424 339 455 9.79E-35 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 Gene3D G3DSA:3.30.390.30 341 464 2.5E-38 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 2.3E-61 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PIRSF PIRSF000350 1 456 2.0E-72 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.3E-33 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-33 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.3E-33 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.3E-33 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.3E-33 T 12-10-2018 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 449 1.1E-32 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 Gene3D G3DSA:3.50.50.60 3 328 8.3E-99 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00880 f11a3459001c1b5c70809fa50397e901 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 322 2.0E-64 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 457 5.7E-135 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 THERU_00880 f11a3459001c1b5c70809fa50397e901 465 SUPERFAMILY SSF51905 1 361 3.09E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00880 f11a3459001c1b5c70809fa50397e901 465 Gene3D G3DSA:3.50.50.60 152 272 8.3E-99 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 SUPERFAMILY SSF51735 102 286 1.0E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Gene3D G3DSA:3.30.70.260 457 530 1.4E-22 T 12-10-2018 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Gene3D G3DSA:3.30.1330.90 324 456 8.8E-37 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 285 9.9E-63 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Pfam PF01842 ACT domain 458 520 8.6E-11 T 12-10-2018 IPR002912 ACT domain THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Gene3D G3DSA:3.40.50.720 5 301 5.7E-118 T 12-10-2018 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Gene3D G3DSA:3.40.50.720 94 287 5.7E-118 T 12-10-2018 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 529 2.9E-220 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 SUPERFAMILY SSF55021 448 526 1.12E-16 T 12-10-2018 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 SUPERFAMILY SSF52283 1 136 1.89E-37 T 12-10-2018 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 2.1E-39 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 THERU_01635 f8cb54da45bbb796c7d96751516ace28 530 SUPERFAMILY SSF143548 324 452 6.28E-34 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Gene3D G3DSA:3.40.50.720 1 140 1.5E-33 T 12-10-2018 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 SUPERFAMILY SSF69055 282 375 4.58E-19 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Pfam PF13288 DXP reductoisomerase C-terminal domain 252 365 9.2E-26 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 372 39.506 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 124 2.2E-29 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 136 219 1.1E-37 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 SUPERFAMILY SSF51735 3 140 6.13E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 Gene3D G3DSA:1.10.1740.10 293 376 4.5E-16 T 12-10-2018 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 PIRSF PIRSF006205 1 376 5.4E-126 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 SUPERFAMILY SSF55347 125 254 7.52E-49 T 12-10-2018 THERU_08305 92853323d07e7baa4ac0b3e224cb96ce 377 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 368 3.2E-104 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 64 7.1E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 SUPERFAMILY SSF47648 2 67 5.1E-17 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 Gene3D G3DSA:1.20.970.10 1 68 2.9E-21 T 12-10-2018 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 333 38.188 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 332 2.0E-126 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 SUPERFAMILY SSF52418 73 335 5.63E-96 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 Pfam PF00591 Glycosyl transferase family, a/b domain 74 323 1.9E-91 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 THERU_07790 cf76c1482047219ea1d07e5be33c3fa2 337 Gene3D G3DSA:3.40.1030.10 69 337 1.1E-106 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 Gene3D G3DSA:3.20.20.120 129 427 9.6E-133 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 SUPERFAMILY SSF51604 141 424 2.69E-122 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 Pfam PF03952 Enolase, N-terminal domain 4 134 5.3E-61 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 1.9E-210 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 SMART SM01192 139 424 9.6E-204 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 421 3.4E-122 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 310 321 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 333 347 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 107 123 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 37 51 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 362 379 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PRINTS PR00148 Enolase signature 161 174 1.9E-41 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 PIRSF PIRSF001400 1 424 4.9E-192 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 Hamap MF_00318 Enolase [eno]. 2 410 44.924 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 SUPERFAMILY SSF54826 4 141 2.8E-58 T 12-10-2018 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 SMART SM01193 4 134 2.4E-97 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 Gene3D G3DSA:3.30.390.10 1 127 5.7E-57 T 12-10-2018 IPR029017 Enolase-like, N-terminal THERU_05590 b3b41553c3f0bb37fbb4ca0ca64fb33a 428 ProSitePatterns PS00164 Enolase signature. 333 346 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 SUPERFAMILY SSF53633 2 297 5.24E-93 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 TIGRFAM TIGR00761 argB: acetylglutamate kinase 26 272 2.2E-80 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 Gene3D G3DSA:3.40.1160.10 5 297 2.3E-99 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 PRINTS PR00474 Glutamate 5-kinase family signature 55 69 8.9E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 PRINTS PR00474 Glutamate 5-kinase family signature 197 224 8.9E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 PRINTS PR00474 Glutamate 5-kinase family signature 247 267 8.9E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 Pfam PF00696 Amino acid kinase family 24 274 7.0E-46 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 PIRSF PIRSF000728 9 297 1.9E-108 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_08025 0ada5fd5370409fb0e7ec2121d515f04 297 Hamap MF_00082 Acetylglutamate kinase [argB]. 23 290 50.096 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Gene3D G3DSA:3.40.1110.10 335 469 4.3E-22 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 66 3.1E-21 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 585 7.3E-23 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 431 449 2.6E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 587 2.6E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 543 559 2.6E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 602 627 2.6E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 321 327 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Pfam PF00122 E1-E2 ATPase 107 299 2.6E-50 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 SUPERFAMILY SSF81653 110 218 2.62E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 SUPERFAMILY SSF56784 318 673 1.14E-53 T 12-10-2018 IPR036412 HAD-like superfamily THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 SUPERFAMILY SSF81665 2 829 6.93E-98 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Gene3D G3DSA:1.20.1110.10 202 333 1.3E-28 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 385 516 1.8E-21 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 205 342 6.7E-24 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 541 660 2.7E-27 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 79 174 1.5E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Gene3D G3DSA:3.40.50.1000 470 521 7.7E-12 T 12-10-2018 IPR023214 HAD superfamily THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Pfam PF00689 Cation transporting ATPase, C-terminus 654 825 1.9E-27 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 SMART SM00831 2 72 3.2E-25 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Gene3D G3DSA:2.70.150.10 90 201 8.1E-33 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 Gene3D G3DSA:1.20.1110.10 581 829 3.1E-37 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 469 480 1.4E-35 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 491 501 1.4E-35 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 606 1.4E-35 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 590 1.4E-35 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 319 333 1.4E-35 T 12-10-2018 THERU_00285 c3baa4a2b5aa6ca9f75e28bd6ec29cd2 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 157 171 1.4E-35 T 12-10-2018 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 252 313 8.0E-21 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 153 5.0E-19 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Gene3D G3DSA:1.10.150.20 232 317 3.1E-27 T 12-10-2018 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Gene3D G3DSA:2.170.120.12 50 170 1.2E-79 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 SUPERFAMILY SSF56553 50 170 4.01E-36 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 2.2E-106 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 312 34.178 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 SMART SM00662 20 227 1.5E-80 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 SUPERFAMILY SSF55257 6 224 4.45E-29 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Gene3D G3DSA:3.30.1360.10 14 220 1.2E-79 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 SUPERFAMILY SSF47789 245 315 3.27E-22 T 12-10-2018 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 220 7.5E-23 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01535 f4c6854a204b02b5308ed7cddbfe7762 317 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 303 3.1E-22 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SUPERFAMILY SSF48452 412 483 6.33E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SUPERFAMILY SSF48452 231 370 1.97E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 467 542 7.5E-7 T 12-10-2018 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 Gene3D G3DSA:1.25.40.10 476 688 1.5E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SMART SM00028 487 516 17.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SMART SM00028 521 554 1.7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SMART SM00028 123 156 54.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SMART SM00028 261 294 36.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SMART SM00028 320 353 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06355 81a9201fd3203ac280bb11b7eeaac7fb 846 SUPERFAMILY SSF48452 485 621 1.66E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 76 89 2.6E-25 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 281 292 2.6E-25 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 43 57 2.6E-25 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 220 230 2.6E-25 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 116 130 2.6E-25 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 255 264 5.2E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 290 5.2E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 5.2E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 5.2E-23 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 SUPERFAMILY SSF53671 2 303 2.49E-99 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 2.0E-46 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 302 9.7E-120 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 300 7.3E-49 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 45 52 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 Gene3D G3DSA:3.40.50.1370 3 129 3.1E-104 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 303 69.592 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THERU_03065 6b887238ff8555ce33f884d4532326c9 305 Gene3D G3DSA:3.40.50.1370 130 298 3.1E-104 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_03405 bf4c7b66836935d78eadbf107a9c7b2b 281 Gene3D G3DSA:3.30.2320.10 144 276 1.8E-76 T 12-10-2018 THERU_03405 bf4c7b66836935d78eadbf107a9c7b2b 281 SUPERFAMILY SSF56563 79 279 1.31E-8 T 12-10-2018 THERU_03405 bf4c7b66836935d78eadbf107a9c7b2b 281 Gene3D G3DSA:3.30.2400.30 2 270 1.8E-76 T 12-10-2018 THERU_03405 bf4c7b66836935d78eadbf107a9c7b2b 281 Pfam PF04454 Encapsulating protein for peroxidase 1 267 1.3E-80 T 12-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 SUPERFAMILY SSF53223 2 119 1.82E-39 T 12-10-2018 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 Gene3D G3DSA:3.40.50.720 3 256 1.2E-108 T 12-10-2018 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 2 118 1.6E-38 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 SUPERFAMILY SSF51735 120 277 9.67E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 121 279 3.3E-65 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 31 53 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 236 252 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 253 271 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 72 99 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 202 231 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 107 128 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 153 173 8.7E-79 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 Gene3D G3DSA:3.40.50.10860 5 273 1.2E-108 T 12-10-2018 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 1 280 36.985 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_05650 1bb2d6ef21aa6f83cee60c84c96ecc6e 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 257 265 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 Gene3D G3DSA:3.20.20.450 46 197 3.7E-19 T 12-10-2018 IPR035919 EAL domain superfamily THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 Gene3D G3DSA:1.10.3210.10 198 404 3.8E-26 T 12-10-2018 THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 SUPERFAMILY SSF141868 7 198 8.11E-26 T 12-10-2018 IPR035919 EAL domain superfamily THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 SMART SM00052 1 197 0.0019 T 12-10-2018 IPR001633 EAL domain THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 Pfam PF00563 EAL domain 59 192 8.8E-15 T 12-10-2018 IPR001633 EAL domain THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 Pfam PF08668 HDOD domain 217 320 6.6E-19 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 PIRSF PIRSF003180 1 405 5.9E-87 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing THERU_07855 ff5de5dd6ef04287bf200b7a2ecac6be 407 SUPERFAMILY SSF109604 183 398 1.22E-34 T 12-10-2018 THERU_02985 203b0971a2f498d75ebf25610473dac2 364 Gene3D G3DSA:3.30.450.90 1 108 2.7E-37 T 12-10-2018 THERU_02985 203b0971a2f498d75ebf25610473dac2 364 SUPERFAMILY SSF52540 12 347 8.93E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02985 203b0971a2f498d75ebf25610473dac2 364 Gene3D G3DSA:3.40.50.300 109 363 1.8E-113 T 12-10-2018 THERU_02985 203b0971a2f498d75ebf25610473dac2 364 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 202 216 - T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_02985 203b0971a2f498d75ebf25610473dac2 364 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 11 352 1.0E-149 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 THERU_02985 203b0971a2f498d75ebf25610473dac2 364 Pfam PF00437 Type II/IV secretion system protein 21 270 1.9E-47 T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_02985 203b0971a2f498d75ebf25610473dac2 364 SMART SM00382 131 256 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:3.10.20.310 202 286 4.0E-19 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:3.10.20.310 91 200 1.7E-11 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:3.10.20.310 369 442 4.6E-22 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:2.40.160.50 444 774 7.6E-69 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:3.10.20.310 18 87 5.2E-16 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Gene3D G3DSA:3.10.20.310 287 368 3.6E-13 T 12-10-2018 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF01103 Surface antigen 469 774 1.2E-62 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 135 774 1.9E-137 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF07244 Surface antigen variable number repeat 371 441 2.9E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF07244 Surface antigen variable number repeat 202 285 4.1E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF07244 Surface antigen variable number repeat 19 87 5.7E-10 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF07244 Surface antigen variable number repeat 90 198 8.5E-9 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 Pfam PF07244 Surface antigen variable number repeat 288 367 8.1E-9 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THERU_00300 e1ebd80fedeed266afb2f7f503f44d01 774 PIRSF PIRSF006076 2 774 1.7E-189 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 8.0E-16 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SUPERFAMILY SSF47364 1 93 1.64E-20 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Pfam PF00448 SRP54-type protein, GTPase domain 97 289 2.6E-70 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SUPERFAMILY SSF47446 292 421 1.96E-44 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SMART SM00382 94 398 5.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Gene3D G3DSA:3.40.50.300 90 279 2.2E-113 T 12-10-2018 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 420 2.0E-168 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SMART SM00963 1 86 7.8E-22 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 434 33.497 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Gene3D G3DSA:1.10.260.30 304 428 5.6E-42 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Pfam PF02978 Signal peptide binding domain 322 418 2.4E-32 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 Gene3D G3DSA:1.20.120.140 5 300 2.2E-113 T 12-10-2018 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SUPERFAMILY SSF52540 96 292 3.38E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 263 276 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_03520 ce0ca520d566555e374f3b7ad2054f1a 437 SMART SM00962 95 290 5.8E-103 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_01110 f0401db054f8d75f2e4813f5650c822b 189 Gene3D G3DSA:3.30.420.40 1 113 5.5E-13 T 12-10-2018 THERU_01110 f0401db054f8d75f2e4813f5650c822b 189 Pfam PF00814 Glycoprotease family 36 98 2.3E-7 T 12-10-2018 IPR000905 Gcp-like domain THERU_01110 f0401db054f8d75f2e4813f5650c822b 189 SUPERFAMILY SSF53067 1 97 9.71E-15 T 12-10-2018 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 343 352 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THERU_04620 82bf9749e13d594650d101fd26d4b875 441 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216 231 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 154 167 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Gene3D G3DSA:3.40.50.300 124 300 2.3E-62 T 12-10-2018 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 SUPERFAMILY SSF52172 1 175 1.25E-32 T 12-10-2018 IPR011006 CheY-like superfamily THERU_04620 82bf9749e13d594650d101fd26d4b875 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 406 423 4.1E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 441 4.1E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Gene3D G3DSA:1.10.8.60 301 367 1.4E-19 T 12-10-2018 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Pfam PF00158 Sigma-54 interaction domain 130 297 4.4E-63 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Pfam PF00072 Response regulator receiver domain 3 111 1.5E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 SMART SM00382 150 293 4.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04620 82bf9749e13d594650d101fd26d4b875 441 SMART SM00448 1 110 6.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 SUPERFAMILY SSF46689 344 440 8.06E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 SUPERFAMILY SSF52540 130 359 8.26E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Pfam PF02954 Bacterial regulatory protein, Fis family 400 438 3.1E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Gene3D G3DSA:1.10.10.60 373 441 1.0E-11 T 12-10-2018 THERU_04620 82bf9749e13d594650d101fd26d4b875 441 Gene3D G3DSA:3.40.50.2300 1 123 1.6E-29 T 12-10-2018 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Gene3D G3DSA:1.10.340.30 16 127 1.3E-74 T 12-10-2018 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 183 199 1.9E-7 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Hamap MF_00942 Endonuclease III [nth]. 1 204 36.174 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 29 165 2.1E-24 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 ProSitePatterns PS01155 Endonuclease III family signature. 97 126 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 SMART SM00478 33 181 9.0E-61 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 SUPERFAMILY SSF48150 2 201 4.71E-67 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Gene3D G3DSA:1.10.1670.10 7 199 1.3E-74 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 Pfam PF00633 Helix-hairpin-helix motif 94 121 1.2E-9 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 SMART SM00525 182 202 2.5E-6 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 TIGRFAM TIGR01083 nth: endonuclease III 2 189 6.0E-76 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THERU_03975 6447520e5eaaef9c89bf0a8ede01ae93 204 PIRSF PIRSF001435 1 204 2.1E-48 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Pfam PF13263 PHP-associated 202 238 2.7E-5 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 SMART SM00481 8 82 1.8E-6 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Gene3D G3DSA:3.40.50.2000 432 547 2.4E-55 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Gene3D G3DSA:3.40.50.2000 548 718 2.4E-55 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Pfam PF00534 Glycosyl transferases group 1 566 714 5.7E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Gene3D G3DSA:3.20.20.140 2 243 1.0E-33 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 SUPERFAMILY SSF53756 380 724 1.26E-67 T 12-10-2018 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 SUPERFAMILY SSF89550 7 241 7.26E-25 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THERU_01615 85bd2082f0699238e66bcb7b7d04ff82 742 Pfam PF13439 Glycosyltransferase Family 4 392 550 2.5E-16 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 149 4.4E-33 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 SUPERFAMILY SSF48179 171 323 2.89E-53 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 Gene3D G3DSA:1.10.1040.10 177 317 2.8E-50 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PIRSF PIRSF000114 1 324 7.6E-96 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 180 201 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 172 311 1.0E-49 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 314 35.465 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 165 189 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 230 247 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 53 80 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 125 145 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 190 214 3.4E-41 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THERU_05235 0496428eac792d60ce67b84fc03a6235 327 SUPERFAMILY SSF51735 1 172 6.27E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05235 0496428eac792d60ce67b84fc03a6235 327 Gene3D G3DSA:3.40.50.720 1 176 1.4E-48 T 12-10-2018 THERU_04955 94bf50b06df253ba26049e29f1ec16a1 326 Gene3D G3DSA:2.120.10.30 21 171 1.2E-15 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THERU_04955 94bf50b06df253ba26049e29f1ec16a1 326 Gene3D G3DSA:2.120.10.30 187 326 2.1E-8 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THERU_04955 94bf50b06df253ba26049e29f1ec16a1 326 Pfam PF01436 NHL repeat 29 54 1.9E-4 T 12-10-2018 IPR001258 NHL repeat GO:0005515 THERU_04955 94bf50b06df253ba26049e29f1ec16a1 326 SUPERFAMILY SSF101898 35 323 6.28E-22 T 12-10-2018 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Gene3D G3DSA:2.60.320.10 43 124 8.5E-83 T 12-10-2018 IPR038690 NusG, domain 2 superfamily THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 SMART SM00739 187 214 1.6E-7 T 12-10-2018 IPR005824 KOW THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 3 241 22.356 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 6 241 1.2E-62 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 SUPERFAMILY SSF50104 186 241 2.71E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 SUPERFAMILY SSF82679 3 179 1.48E-20 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 PRINTS PR00338 Transcription termination factor NUSG signature 124 136 1.4E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 PRINTS PR00338 Transcription termination factor NUSG signature 199 214 1.4E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 PRINTS PR00338 Transcription termination factor NUSG signature 217 233 1.4E-18 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 SMART SM00738 3 177 4.9E-26 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Pfam PF00467 KOW motif 190 220 4.1E-8 T 12-10-2018 IPR005824 KOW THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 ProSitePatterns PS01014 Transcription termination factor nusG signature. 224 233 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Gene3D G3DSA:2.30.30.30 180 241 2.4E-26 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Pfam PF07009 NusG domain II 43 117 1.7E-10 T 12-10-2018 IPR024045 NusG, domain 2 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 SUPERFAMILY SSF82004 44 123 2.48E-41 T 12-10-2018 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Pfam PF02357 Transcription termination factor nusG 5 173 1.6E-27 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THERU_07270 3991eaf7e2bda2225f274a9ed5683339 241 Gene3D G3DSA:3.30.70.940 3 178 8.5E-83 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THERU_02030 1900f26d87ce3f05971fac759d31508e 296 Pfam PF13435 Cytochrome c554 and c-prime 35 104 5.5E-11 T 12-10-2018 IPR023155 Cytochrome c-552/4 THERU_02030 1900f26d87ce3f05971fac759d31508e 296 SUPERFAMILY SSF48695 33 166 6.63E-23 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily THERU_02030 1900f26d87ce3f05971fac759d31508e 296 Gene3D G3DSA:3.90.10.10 42 164 2.0E-7 T 12-10-2018 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 SUPERFAMILY SSF89000 320 479 1.69E-47 T 12-10-2018 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 600 617 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 SUPERFAMILY SSF51569 22 313 3.11E-80 T 12-10-2018 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 SUPERFAMILY SSF51230 573 644 8.77E-22 T 12-10-2018 IPR011053 Single hybrid motif THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 Gene3D G3DSA:3.20.20.70 3 480 1.1E-157 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 Pfam PF00682 HMGL-like 26 292 3.1E-41 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 Pfam PF00364 Biotin-requiring enzyme 579 643 4.8E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 Gene3D G3DSA:2.40.50.100 571 645 6.9E-25 T 12-10-2018 THERU_03935 bac6fa69468c36ea2dd5a7b1796af4b2 654 Pfam PF02436 Conserved carboxylase domain 315 519 7.5E-48 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 PIRSF PIRSF000709 1 123 0.0015 T 12-10-2018 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 SUPERFAMILY SSF52540 2 167 4.63E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 Pfam PF13671 AAA domain 2 144 6.6E-25 T 12-10-2018 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 PRINTS PR01100 Shikimate kinase family signature 3 18 1.3E-5 T 12-10-2018 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 PRINTS PR01100 Shikimate kinase family signature 27 40 1.3E-5 T 12-10-2018 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 PRINTS PR01100 Shikimate kinase family signature 104 121 1.3E-5 T 12-10-2018 THERU_01045 42a1dffa80475770b4c21ee483d86aac 169 Gene3D G3DSA:3.40.50.300 1 168 7.2E-32 T 12-10-2018 THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 13 367 4.0E-137 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 Pfam PF00155 Aminotransferase class I and II 26 363 1.2E-63 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 Gene3D G3DSA:3.40.640.10 36 276 8.8E-124 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 223 232 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 SUPERFAMILY SSF53383 24 369 5.03E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_06845 b6cda4e01ad82df4f262b6e8a5057095 377 Gene3D G3DSA:3.90.1150.10 26 363 8.8E-124 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_04920 7720cb098b29ce923c8a22ea0ff66e18 143 Pfam PF07849 Protein of unknown function (DUF1641) 104 140 4.8E-13 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.274.100 679 750 3.6E-20 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:2.40.50.100 1131 1211 8.0E-13 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 321 1335 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 SUPERFAMILY SSF51246 1341 1391 1.82E-5 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 SUPERFAMILY SSF64484 8 1546 0.0 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.40.90 499 541 1.1E-19 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.274.100 615 678 7.4E-23 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 SMART SM00663 361 639 1.3E-172 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1556 18.856 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Pfam PF04997 RNA polymerase Rpb1, domain 1 8 467 1.2E-84 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Pfam PF00623 RNA polymerase Rpb1, domain 2 469 610 2.5E-32 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Pfam PF04983 RNA polymerase Rpb1, domain 3 614 754 1.8E-31 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.150.390 1495 1558 2.0E-26 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.132.30 751 898 4.0E-60 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Pfam PF04998 RNA polymerase Rpb1, domain 5 874 1491 3.4E-75 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:2.40.50.100 1057 1130 4.6E-21 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:1.10.1790.20 1395 1493 8.3E-52 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Pfam PF05000 RNA polymerase Rpb1, domain 4 783 871 1.3E-16 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:2.40.50.100 1339 1394 8.3E-52 T 12-10-2018 THERU_07305 d137dbfdee3434bdcd6a41fb3e63f59f 1560 Gene3D G3DSA:2.40.50.100 1277 1336 1.7E-15 T 12-10-2018 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 SUPERFAMILY SSF52096 17 267 3.06E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 Pfam PF01039 Carboxyl transferase domain 88 230 2.5E-15 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 8 270 1.5E-113 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 271 37.164 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 Gene3D G3DSA:3.90.226.10 17 274 1.2E-76 T 12-10-2018 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 219 230 3.8E-40 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 119 133 3.8E-40 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 190 207 3.8E-40 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 241 250 3.8E-40 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_07150 251ddd5801cf5b3ec2b61cecf530379a 278 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 153 171 3.8E-40 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 104 125 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 227 250 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 159 182 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 202 223 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 183 201 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 57 79 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 PRINTS PR00721 Stomatin signature 139 156 3.1E-71 T 12-10-2018 IPR001972 Stomatin family GO:0016020 THERU_00655 3de23a3f35f601a3ed7323c132071530 287 Pfam PF01145 SPFH domain / Band 7 family 54 223 5.1E-38 T 12-10-2018 IPR001107 Band 7 domain THERU_00655 3de23a3f35f601a3ed7323c132071530 287 SUPERFAMILY SSF117892 81 214 4.71E-46 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily THERU_00655 3de23a3f35f601a3ed7323c132071530 287 ProSitePatterns PS01270 Band 7 protein family signature. 163 191 - T 12-10-2018 IPR018080 Band 7/stomatin-like, conserved site THERU_00655 3de23a3f35f601a3ed7323c132071530 287 SMART SM00244 50 207 4.3E-73 T 12-10-2018 IPR001107 Band 7 domain THERU_00655 3de23a3f35f601a3ed7323c132071530 287 Gene3D G3DSA:3.30.479.30 78 209 1.0E-52 T 12-10-2018 THERU_07460 eafa4954fd69fee37222bb34e71ebb7d 241 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 241 111.071 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THERU_07460 eafa4954fd69fee37222bb34e71ebb7d 241 SUPERFAMILY SSF63892 1 240 4.84E-90 T 12-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THERU_07460 eafa4954fd69fee37222bb34e71ebb7d 241 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 2 239 1.4E-95 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THERU_07460 eafa4954fd69fee37222bb34e71ebb7d 241 Gene3D G3DSA:3.20.20.70 1 241 2.8E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07460 eafa4954fd69fee37222bb34e71ebb7d 241 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 2 240 2.3E-107 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 PIRSF PIRSF038945 1 352 3.0E-169 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 SUPERFAMILY SSF53686 4 347 2.36E-109 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 320 2.8E-74 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 Gene3D G3DSA:3.40.50.1100 14 327 1.0E-136 T 12-10-2018 THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 TIGRFAM TIGR00260 thrC: threonine synthase 8 327 1.2E-101 T 12-10-2018 IPR004450 Threonine synthase-like THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 54 67 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THERU_00685 da9bf358284a4d10ad9d6f679882c6c7 352 Gene3D G3DSA:3.40.50.1100 62 158 1.0E-136 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 SUPERFAMILY SSF51735 5 126 1.09E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 Gene3D G3DSA:3.40.50.261 128 307 5.8E-41 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 PIRSF PIRSF001553 1 312 2.2E-118 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 SMART SM00881 6 104 8.8E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 Pfam PF02629 CoA binding domain 8 103 3.6E-22 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 4.1E-21 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 4.1E-21 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 PRINTS PR01798 Succinyl-CoA synthase signature 256 273 4.1E-21 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 4.1E-21 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 Gene3D G3DSA:3.40.50.720 4 127 2.1E-39 T 12-10-2018 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 Pfam PF00549 CoA-ligase 160 278 6.3E-10 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06635 e58d5d48f0189050b3997ff6e0bcbf8c 339 SUPERFAMILY SSF52210 148 308 2.88E-28 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_02520 ed727b0beb83b61e9d41cded343a2891 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 94 9.3E-21 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THERU_02520 ed727b0beb83b61e9d41cded343a2891 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 100 18.176 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 PIRSF PIRSF006769 1 358 4.2E-134 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 Gene3D G3DSA:3.40.140.10 1 135 2.3E-46 T 12-10-2018 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 SUPERFAMILY SSF53927 3 144 1.51E-47 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 Pfam PF01872 RibD C-terminal domain 147 345 4.1E-51 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 Gene3D G3DSA:3.40.430.10 136 357 2.7E-70 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 353 5.3E-116 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 355 9.2E-55 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 SUPERFAMILY SSF53597 145 354 2.14E-57 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THERU_03470 86053bfe38ab8b762639359b7e0939a0 358 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 2.2E-21 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THERU_06175 deb926b4db7f339025414a00fa72a684 430 Gene3D G3DSA:3.50.50.100 1 430 1.7E-172 T 12-10-2018 THERU_06175 deb926b4db7f339025414a00fa72a684 430 SUPERFAMILY SSF51905 115 240 6.22E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06175 deb926b4db7f339025414a00fa72a684 430 SUPERFAMILY SSF51905 3 333 2.11E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06175 deb926b4db7f339025414a00fa72a684 430 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 296 1.0E-17 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_03485 e3af9c64e1fe9f2e099958e545fde4db 246 Pfam PF00691 OmpA family 126 224 1.3E-24 T 12-10-2018 IPR006665 OmpA-like domain THERU_03485 e3af9c64e1fe9f2e099958e545fde4db 246 Gene3D G3DSA:3.30.1330.60 78 240 1.8E-54 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_03485 e3af9c64e1fe9f2e099958e545fde4db 246 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 55 5.9E-15 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain THERU_03485 e3af9c64e1fe9f2e099958e545fde4db 246 SUPERFAMILY SSF103088 116 231 1.15E-36 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_04150 0421a77c25f8bcd10c1d8cb1a0bebe69 139 Pfam PF04238 Protein of unknown function (DUF420) 7 132 5.7E-35 T 12-10-2018 IPR007352 Protein of unknown function DUF420 THERU_04405 5cddf9fb273f6d8c7270874891edaccc 103 SUPERFAMILY SSF158568 2 97 2.48E-15 T 12-10-2018 IPR023101 AF1862-like domain superfamily THERU_04405 5cddf9fb273f6d8c7270874891edaccc 103 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 2 99 1.6E-14 T 12-10-2018 IPR010160 CRISPR-associated protein, Cmr5 THERU_04405 5cddf9fb273f6d8c7270874891edaccc 103 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 3 94 3.7E-11 T 12-10-2018 IPR010160 CRISPR-associated protein, Cmr5 THERU_04405 5cddf9fb273f6d8c7270874891edaccc 103 Gene3D G3DSA:1.10.520.30 1 100 2.7E-14 T 12-10-2018 IPR023101 AF1862-like domain superfamily THERU_05380 92241782ec2daca50a7b83853e2dc3eb 269 SUPERFAMILY SSF53613 1 263 2.96E-87 T 12-10-2018 IPR029056 Ribokinase-like THERU_05380 92241782ec2daca50a7b83853e2dc3eb 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 259 2.0E-105 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_05380 92241782ec2daca50a7b83853e2dc3eb 269 Gene3D G3DSA:3.40.1190.20 1 267 6.3E-110 T 12-10-2018 IPR029056 Ribokinase-like THERU_05380 92241782ec2daca50a7b83853e2dc3eb 269 Pfam PF08543 Phosphomethylpyrimidine kinase 13 257 4.8E-100 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 THERU_08090 61f2d4d8f2572968672d22ef12e49e1a 361 Gene3D G3DSA:3.90.1720.10 211 360 1.2E-23 T 12-10-2018 THERU_08090 61f2d4d8f2572968672d22ef12e49e1a 361 SUPERFAMILY SSF54001 227 277 1.42E-9 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THERU_08090 61f2d4d8f2572968672d22ef12e49e1a 361 Pfam PF00877 NlpC/P60 family 235 276 4.8E-7 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain THERU_08090 61f2d4d8f2572968672d22ef12e49e1a 361 Pfam PF12913 SH3 domain (SH3b1 type) 107 146 7.2E-15 T 12-10-2018 IPR039439 SH3b1 domain THERU_08175 03de292e2fa334c1730590a6786e0584 339 SMART SM00729 72 278 5.3E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_08175 03de292e2fa334c1730590a6786e0584 339 Pfam PF04055 Radical SAM superfamily 79 229 1.2E-20 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_08175 03de292e2fa334c1730590a6786e0584 339 SUPERFAMILY SSF102114 48 313 2.35E-38 T 12-10-2018 THERU_08175 03de292e2fa334c1730590a6786e0584 339 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 338 1.6E-111 T 12-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme THERU_08175 03de292e2fa334c1730590a6786e0584 339 PIRSF PIRSF004869 1 313 1.0E-103 T 12-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THERU_08175 03de292e2fa334c1730590a6786e0584 339 Pfam PF13353 4Fe-4S single cluster domain 75 180 1.1E-6 T 12-10-2018 THERU_08175 03de292e2fa334c1730590a6786e0584 339 Gene3D G3DSA:3.20.20.70 65 286 6.9E-36 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07820 506d726b48b2d8e416acae439b3ed2be 61 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 58 20.773 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07820 506d726b48b2d8e416acae439b3ed2be 61 SUPERFAMILY SSF57829 1 58 1.65E-22 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THERU_07820 506d726b48b2d8e416acae439b3ed2be 61 Pfam PF01783 Ribosomal L32p protein family 2 60 7.9E-30 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07820 506d726b48b2d8e416acae439b3ed2be 61 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 59 6.7E-27 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 67 90 2.0E-50 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 298 324 2.0E-50 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 2.0E-50 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 2.0E-50 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 47 65 2.0E-50 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 Gene3D G3DSA:3.90.640.10 185 257 4.2E-123 T 12-10-2018 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 Gene3D G3DSA:3.30.420.40 12 325 4.2E-123 T 12-10-2018 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 SUPERFAMILY SSF53067 148 326 3.27E-43 T 12-10-2018 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 8 334 3.0E-144 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 SUPERFAMILY SSF53067 9 147 1.3E-39 T 12-10-2018 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 Pfam PF06723 MreB/Mbl protein 10 333 8.4E-138 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THERU_01190 9632f65200fc511ee06d78b56e04a290 339 Gene3D G3DSA:3.30.420.40 153 315 4.2E-123 T 12-10-2018 THERU_04280 c3508fd682018938c2bf2101765e449c 184 Gene3D G3DSA:3.90.950.10 2 183 3.7E-59 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THERU_04280 c3508fd682018938c2bf2101765e449c 184 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 176 2.0E-46 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 THERU_04280 c3508fd682018938c2bf2101765e449c 184 Pfam PF02545 Maf-like protein 4 181 1.8E-52 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 THERU_04280 c3508fd682018938c2bf2101765e449c 184 SUPERFAMILY SSF52972 3 181 2.03E-53 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THERU_04280 c3508fd682018938c2bf2101765e449c 184 Hamap MF_00528 Septum formation protein Maf [maf]. 3 183 25.966 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 THERU_04280 c3508fd682018938c2bf2101765e449c 184 PIRSF PIRSF006305 2 184 2.5E-50 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 THERU_00985 43449b4b72cd4a0135298f1c9481c9a3 160 Pfam PF02577 Bifunctional nuclease 6 132 4.0E-45 T 12-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 THERU_00985 43449b4b72cd4a0135298f1c9481c9a3 160 Gene3D G3DSA:3.10.690.10 1 143 9.1E-50 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 THERU_00985 43449b4b72cd4a0135298f1c9481c9a3 160 SUPERFAMILY SSF103256 1 139 1.44E-45 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 351 33.113 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 Gene3D G3DSA:3.20.20.20 1 254 2.0E-108 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 Pfam PF04551 GcpE protein 5 345 1.4E-131 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2 344 8.0E-142 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 PIRSF PIRSF004640 1 353 4.1E-148 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 SUPERFAMILY SSF51604 15 131 1.52E-7 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 SUPERFAMILY SSF56014 259 345 6.02E-10 T 12-10-2018 THERU_07025 de0033362908a7f3ab6fa63fc20d683f 354 Gene3D G3DSA:3.30.413.10 255 353 6.4E-37 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.70.1430 38 789 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Pfam PF00873 AcrB/AcrD/AcrF family 1 998 1.1E-267 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82693 133 317 4.53E-21 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:1.20.1640.10 8 491 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82866 284 483 3.4E-43 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.70.1320 132 319 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.70.1440 643 838 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 432 455 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 531 548 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 350 371 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 599 613 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 PRINTS PR00702 Acriflavin resistance protein family signature 323 346 4.2E-66 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:1.20.1640.10 492 995 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82714 182 256 1.03E-9 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82714 694 780 5.36E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.2090.10 693 781 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.2090.10 176 262 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82866 777 1003 1.1E-49 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82693 38 131 1.28E-26 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 Gene3D G3DSA:3.30.70.1430 546 642 0.0 T 12-10-2018 THERU_00690 4574ab0c11fd6ef364058ecba937220a 1009 SUPERFAMILY SSF82693 545 638 1.57E-15 T 12-10-2018 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 393 47.438 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 SUPERFAMILY SSF52374 4 312 4.8E-99 T 12-10-2018 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Pfam PF00579 tRNA synthetases class I (W and Y) 30 312 8.5E-86 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 SUPERFAMILY SSF55174 294 392 9.55E-17 T 12-10-2018 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 SMART SM00363 332 393 0.0098 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Gene3D G3DSA:1.10.240.10 218 324 6.6E-36 T 12-10-2018 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Pfam PF01479 S4 domain 337 378 2.3E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 391 2.2E-124 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Gene3D G3DSA:3.10.290.10 325 392 1.5E-16 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 2.0E-27 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 2.0E-27 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 2.0E-27 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 2.0E-27 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THERU_07110 3af06e3a6f35704ffc46314f56aca185 394 Gene3D G3DSA:3.40.50.620 4 217 2.7E-78 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Pfam PF13155 Toprim-like 243 327 3.1E-18 T 12-10-2018 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Hamap MF_00974 DNA primase [dnaG]. 1 497 24.649 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 SUPERFAMILY SSF57783 3 92 1.67E-30 T 12-10-2018 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 SMART SM00493 240 311 3.6E-16 T 12-10-2018 IPR006171 TOPRIM domain THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Pfam PF08275 DNA primase catalytic core, N-terminal domain 111 231 1.4E-34 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Gene3D G3DSA:3.90.580.10 1 95 7.0E-34 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Pfam PF01807 CHC2 zinc finger 4 93 3.0E-30 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 SUPERFAMILY SSF56731 101 388 3.27E-78 T 12-10-2018 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 SMART SM00400 29 83 8.9E-22 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 PIRSF PIRSF002811 2 503 6.8E-133 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Gene3D G3DSA:3.40.1360.10 222 344 7.0E-37 T 12-10-2018 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 TIGRFAM TIGR01391 dnaG: DNA primase 4 359 4.5E-118 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 THERU_07610 72abc9729c00c26d1b34985a0d11f99e 513 Gene3D G3DSA:3.90.980.10 96 221 9.5E-38 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Gene3D G3DSA:3.30.930.10 122 594 8.4E-193 T 12-10-2018 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 570 1.5E-108 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Pfam PF02938 GAD domain 313 405 2.8E-29 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.5E-17 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 596 34.529 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 SUPERFAMILY SSF55681 117 596 3.11E-105 T 12-10-2018 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 SUPERFAMILY SSF50249 4 108 2.1E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Gene3D G3DSA:3.30.1360.30 277 419 8.4E-193 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 Gene3D G3DSA:2.40.50.140 1 110 1.5E-34 T 12-10-2018 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 486 502 1.0E-23 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 1.0E-23 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 530 544 1.0E-23 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 1.0E-23 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 596 1.7E-233 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THERU_06925 b7da088db06c01e9e2d7d19123536cfc 599 SUPERFAMILY SSF55261 294 418 4.74E-41 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 THERU_06800 85e882eb61b32d2347b7c10bc4adf3a8 111 Gene3D G3DSA:1.10.530.10 1 111 2.6E-21 T 12-10-2018 THERU_06800 85e882eb61b32d2347b7c10bc4adf3a8 111 SUPERFAMILY SSF53955 1 108 3.49E-28 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily THERU_06800 85e882eb61b32d2347b7c10bc4adf3a8 111 Pfam PF01464 Transglycosylase SLT domain 1 92 1.3E-20 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 THERU_01145 a50870bc27e66b90105a6079841b8509 549 Gene3D G3DSA:1.10.530.10 403 549 8.3E-48 T 12-10-2018 THERU_01145 a50870bc27e66b90105a6079841b8509 549 SUPERFAMILY SSF48452 131 308 1.44E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_01145 a50870bc27e66b90105a6079841b8509 549 Pfam PF01464 Transglycosylase SLT domain 413 512 1.1E-27 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 THERU_01145 a50870bc27e66b90105a6079841b8509 549 Gene3D G3DSA:1.25.40.10 191 309 5.2E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_01145 a50870bc27e66b90105a6079841b8509 549 SUPERFAMILY SSF53955 408 547 6.68E-44 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily THERU_01145 a50870bc27e66b90105a6079841b8509 549 Pfam PF13181 Tetratricopeptide repeat 153 178 0.17 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_01145 a50870bc27e66b90105a6079841b8509 549 SMART SM00028 152 185 73.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_01145 a50870bc27e66b90105a6079841b8509 549 SMART SM00028 243 276 0.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_01145 a50870bc27e66b90105a6079841b8509 549 Pfam PF13432 Tetratricopeptide repeat 256 306 5.8E-5 T 12-10-2018 THERU_01145 a50870bc27e66b90105a6079841b8509 549 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 430 458 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THERU_01145 a50870bc27e66b90105a6079841b8509 549 Gene3D G3DSA:1.25.40.10 36 182 3.9E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_02515 3d871224522f903934901b8a2086a039 637 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 568 3.1E-180 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02515 3d871224522f903934901b8a2086a039 637 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 119 8.5E-13 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 155 176 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 9.9E-52 T 12-10-2018 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 354 376 5.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 80 100 5.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 260 282 5.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 5.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02515 3d871224522f903934901b8a2086a039 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 33 52 5.6E-14 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THERU_02515 3d871224522f903934901b8a2086a039 637 Pfam PF00361 Proton-conducting membrane transporter 131 419 3.4E-83 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 1.6E-12 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 258 269 1.6E-12 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 342 355 1.6E-12 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 371 48.866 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 366 1.1E-153 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 SUPERFAMILY SSF52021 2 148 2.09E-60 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 Gene3D G3DSA:3.50.30.20 1 149 4.4E-62 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 2.2E-36 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 2.2E-36 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 300 311 2.2E-36 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 292 2.2E-36 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 274 2.2E-36 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 SMART SM01097 2 132 3.5E-95 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 131 1.2E-55 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 Pfam PF00117 Glutamine amidotransferase class-I 191 365 6.5E-43 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 SUPERFAMILY SSF52317 153 369 5.13E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.7E-7 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00097 Anthranilate synthase component II signature 258 269 1.7E-7 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 PRINTS PR00097 Anthranilate synthase component II signature 342 355 1.7E-7 T 12-10-2018 THERU_06445 4890eec7d41f54c5728bbbf87b8cd35c 371 Gene3D G3DSA:3.40.50.880 150 369 8.0E-67 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_02670 84d308fc0863915680b9701325a7ddd5 159 PIRSF PIRSF037663 2 145 4.5E-11 T 12-10-2018 IPR017255 Acetyltransferase, GNAT, predicted THERU_02670 84d308fc0863915680b9701325a7ddd5 159 SUPERFAMILY SSF55729 1 146 5.79E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase THERU_02670 84d308fc0863915680b9701325a7ddd5 159 Pfam PF00583 Acetyltransferase (GNAT) family 33 137 2.9E-23 T 12-10-2018 IPR000182 GNAT domain THERU_02670 84d308fc0863915680b9701325a7ddd5 159 Gene3D G3DSA:3.40.630.30 1 155 7.4E-42 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Gene3D G3DSA:3.30.70.260 339 419 5.9E-161 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 SUPERFAMILY SSF55021 342 419 4.58E-11 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Pfam PF01842 ACT domain 344 417 8.2E-16 T 12-10-2018 IPR002912 ACT domain THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Gene3D G3DSA:3.40.50.720 3 332 5.9E-161 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 PIRSF PIRSF000098 1 431 1.8E-162 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 180 202 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 SUPERFAMILY SSF55347 134 299 1.31E-53 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 SUPERFAMILY SSF51735 3 155 5.22E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Pfam PF00742 Homoserine dehydrogenase 134 312 2.4E-62 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Gene3D G3DSA:3.30.360.10 133 338 5.9E-161 T 12-10-2018 THERU_00515 a4e88e17f9b85f5c514f7d7a2c2bfa0b 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 123 1.9E-19 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THERU_05810 0379c84f9b809a0ee48c4af6893255f3 179 SMART SM01007 6 178 3.7E-41 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal THERU_05810 0379c84f9b809a0ee48c4af6893255f3 179 SUPERFAMILY SSF53639 5 178 3.53E-44 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THERU_05810 0379c84f9b809a0ee48c4af6893255f3 179 Gene3D G3DSA:3.40.225.10 4 179 4.9E-52 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THERU_05810 0379c84f9b809a0ee48c4af6893255f3 179 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 177 1.3E-40 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 SUPERFAMILY SSF56719 25 479 3.27E-172 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 SMART SM00434 6 459 1.1E-270 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Gene3D G3DSA:3.30.1360.40 231 327 1.5E-204 T 12-10-2018 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Gene3D G3DSA:3.90.199.10 27 479 1.5E-204 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Gene3D G3DSA:1.10.268.10 364 453 1.5E-204 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 27 461 4.6E-160 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 668 702 0.25 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 569 611 7.0E-7 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 618 663 3.8E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 SUPERFAMILY SSF101904 521 728 1.31E-32 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THERU_01910 c783259d2ab806e0a6759342b9eb01fa 756 Gene3D G3DSA:2.120.10.90 491 756 4.2E-67 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THERU_04610 d39e3aabd933356b866196a7ae0b7167 275 Gene3D G3DSA:3.40.190.10 33 243 9.4E-48 T 12-10-2018 THERU_04610 d39e3aabd933356b866196a7ae0b7167 275 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 32 234 3.7E-35 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 THERU_04610 d39e3aabd933356b866196a7ae0b7167 275 Gene3D G3DSA:3.40.190.10 102 210 9.4E-48 T 12-10-2018 THERU_04610 d39e3aabd933356b866196a7ae0b7167 275 SUPERFAMILY SSF53850 25 244 7.36E-39 T 12-10-2018 THERU_04610 d39e3aabd933356b866196a7ae0b7167 275 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 33 261 2.6E-49 T 12-10-2018 THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 33 52 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 250 276 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 129 153 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 396 413 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 342 361 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 52 68 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PRINTS PR01806 Virulence factor MviN signature 153 174 1.5E-49 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 Pfam PF03023 MviN-like protein 28 450 8.0E-109 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 473 5.8E-118 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 PIRSF PIRSF002869 1 486 1.1E-122 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06160 3ba4162b2e4cb367d69837c6248a7d21 492 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 451 18.081 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06870 13b5c946d736b3fd6506edbde9a6bacc 311 SUPERFAMILY SSF53335 103 245 5.46E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_06870 13b5c946d736b3fd6506edbde9a6bacc 311 Gene3D G3DSA:1.20.120.1180 13 306 6.8E-105 T 12-10-2018 THERU_06870 13b5c946d736b3fd6506edbde9a6bacc 311 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 165 261 2.4E-30 T 12-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 THERU_06870 13b5c946d736b3fd6506edbde9a6bacc 311 Gene3D G3DSA:3.40.50.150 49 284 6.8E-105 T 12-10-2018 THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 SUPERFAMILY SSF55326 388 565 8.37E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Gene3D G3DSA:3.90.650.10 20 348 9.2E-128 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Gene3D G3DSA:3.30.1330.10 37 185 9.2E-128 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 SUPERFAMILY SSF56042 192 417 8.52E-50 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 742 284.621 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Gene3D G3DSA:3.30.1330.10 374 563 1.1E-59 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Gene3D G3DSA:3.90.650.10 567 742 2.6E-38 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 10 742 7.8E-283 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 80 181 2.3E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 432 559 9.1E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 PIRSF PIRSF001587 1 742 3.7E-304 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 SUPERFAMILY SSF56042 569 741 4.49E-36 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 573 715 3.7E-15 T 12-10-2018 IPR010918 PurM-like, C-terminal domain THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 193 343 2.6E-31 T 12-10-2018 IPR010918 PurM-like, C-terminal domain THERU_06970 8934a6a4d1b0a8e305007bd48d5bef28 742 SUPERFAMILY SSF55326 10 185 3.59E-50 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 SMART SM00490 254 335 1.6E-36 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 Gene3D G3DSA:3.40.50.300 1 207 6.2E-75 T 12-10-2018 THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 SUPERFAMILY SSF52540 68 355 2.49E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 Pfam PF00270 DEAD/DEAH box helicase 25 191 4.3E-52 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 Gene3D G3DSA:3.40.50.300 208 365 4.4E-54 T 12-10-2018 THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 SMART SM00487 20 217 6.4E-60 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_06610 de6b0be68e4ee5ddd491e6fe76aef3ce 367 Pfam PF00271 Helicase conserved C-terminal domain 227 335 2.1E-32 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 SMART SM01329 5 352 8.5E-212 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 356 51.328 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 352 2.3E-140 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 352 3.9E-166 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 SUPERFAMILY SSF53659 4 357 2.5E-127 T 12-10-2018 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THERU_00710 3f06a742f5f123f12611cf4d693e8366 363 Gene3D G3DSA:3.40.718.10 3 359 6.6E-153 T 12-10-2018 THERU_06835 cb5df8ccd6d142f9d396095cef202f79 218 Pfam PF01695 IstB-like ATP binding protein 76 210 1.1E-14 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 THERU_06835 cb5df8ccd6d142f9d396095cef202f79 218 Gene3D G3DSA:3.40.50.300 28 201 7.0E-36 T 12-10-2018 THERU_06835 cb5df8ccd6d142f9d396095cef202f79 218 SUPERFAMILY SSF52540 42 201 2.06E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04655 ffa1207e1aa9a43dd915667b648db1d5 405 Gene3D G3DSA:3.40.190.10 31 388 5.2E-124 T 12-10-2018 THERU_04655 ffa1207e1aa9a43dd915667b648db1d5 405 Pfam PF13379 NMT1-like family 30 278 1.7E-88 T 12-10-2018 THERU_04655 ffa1207e1aa9a43dd915667b648db1d5 405 Gene3D G3DSA:3.40.190.10 118 393 5.2E-124 T 12-10-2018 THERU_04655 ffa1207e1aa9a43dd915667b648db1d5 405 SUPERFAMILY SSF53850 30 273 1.48E-31 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 508 54.658 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 SUPERFAMILY SSF52402 180 429 3.97E-54 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.1E-8 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 3.1E-8 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 3.1E-8 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Gene3D G3DSA:3.30.300.10 389 508 1.8E-54 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 191 1.5E-77 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Pfam PF00117 Glutamine amidotransferase class-I 7 187 1.7E-42 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 199 508 1.5E-148 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 SUPERFAMILY SSF52317 4 224 9.74E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Gene3D G3DSA:3.40.50.620 196 388 6.4E-73 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00097 Anthranilate synthase component II signature 76 87 1.7E-7 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.7E-7 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.7E-7 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 SUPERFAMILY SSF54810 388 508 3.14E-53 T 12-10-2018 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Pfam PF02540 NAD synthase 202 260 1.3E-5 T 12-10-2018 IPR022310 NAD/GMP synthase THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Pfam PF00958 GMP synthase C terminal domain 416 507 8.2E-46 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THERU_03700 756cc4392b7c4d42fe0b55d041da04fd 508 Gene3D G3DSA:3.40.50.880 2 192 1.2E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_02875 585b18dd82df2907149cabc237d40e01 437 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 4 433 34.521 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 THERU_02875 585b18dd82df2907149cabc237d40e01 437 SUPERFAMILY SSF51905 2 366 5.42E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_02875 585b18dd82df2907149cabc237d40e01 437 Gene3D G3DSA:3.50.50.60 293 436 8.0E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_02875 585b18dd82df2907149cabc237d40e01 437 Gene3D G3DSA:3.50.50.60 1 177 2.5E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_02875 585b18dd82df2907149cabc237d40e01 437 Pfam PF01134 Glucose inhibited division protein A 3 366 1.0E-101 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 THERU_02875 585b18dd82df2907149cabc237d40e01 437 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 433 2.2E-215 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SUPERFAMILY SSF55874 404 555 1.11E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 Gene3D G3DSA:1.10.287.130 342 407 1.3E-5 T 12-10-2018 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SUPERFAMILY SSF47384 347 409 3.34E-5 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 Gene3D G3DSA:3.30.565.10 408 557 2.4E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SMART SM00387 453 557 1.8E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SUPERFAMILY SSF55785 222 337 6.47E-12 T 12-10-2018 IPR035965 PAS domain superfamily THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 455 556 2.0E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 Gene3D G3DSA:3.30.450.20 228 341 6.9E-14 T 12-10-2018 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SMART SM00091 235 301 0.0086 T 12-10-2018 IPR000014 PAS domain THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 Pfam PF13426 PAS domain 246 338 1.2E-7 T 12-10-2018 IPR000014 PAS domain THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 SMART SM00388 354 413 4.0E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 537 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 556 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 504 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 518 1.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_04615 0796737ce438c087f181ee4316e1ddb0 557 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 344 1.7E-10 T 12-10-2018 IPR000014 PAS domain THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 153 8.5E-37 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 SUPERFAMILY SSF51735 3 153 1.53E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 Gene3D G3DSA:1.10.1040.10 167 297 2.4E-47 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 SMART SM01350 167 296 1.5E-5 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 3 298 7.7E-126 T 12-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 1.2E-18 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 1.2E-18 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 2 25 1.2E-18 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 277 1.3E-22 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 Gene3D G3DSA:3.40.50.720 1 166 3.1E-43 T 12-10-2018 THERU_06010 daf11c1d898c2cb4b3b5b9d240538301 299 SUPERFAMILY SSF48179 165 279 8.16E-39 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_02115 caa1763b9716835b9e0de472013201b6 320 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 9 317 1.2E-49 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THERU_02115 caa1763b9716835b9e0de472013201b6 320 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 14 303 3.8E-45 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THERU_07930 8a4cf70cd5927766aa68808602032a52 426 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 155 7.7E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 173 336 2.7E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Pfam PF01926 50S ribosome-binding GTPase 174 291 7.1E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Pfam PF01926 50S ribosome-binding GTPase 3 118 3.4E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 348 422 5.1E-19 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like THERU_07930 8a4cf70cd5927766aa68808602032a52 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 174 194 7.7E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 223 238 7.7E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 PIRSF PIRSF006485 1 426 7.8E-153 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Gene3D G3DSA:3.30.300.20 342 425 4.6E-22 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Hamap MF_00195 GTPase Der [der]. 1 425 36.11 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 SUPERFAMILY SSF52540 3 165 2.0E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Gene3D G3DSA:3.40.50.300 2 159 1.5E-46 T 12-10-2018 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 Gene3D G3DSA:3.40.50.300 166 341 1.1E-48 T 12-10-2018 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 422 1.0E-151 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THERU_07930 8a4cf70cd5927766aa68808602032a52 426 SUPERFAMILY SSF52540 136 425 3.49E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 4 142 7.8E-44 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 71 84 1.9E-19 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 88 102 1.9E-19 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 116 1.9E-19 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 Pfam PF00364 Biotin-requiring enzyme 68 141 1.9E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 Gene3D G3DSA:2.40.50.100 63 142 4.7E-31 T 12-10-2018 THERU_07955 37d8e96a2e5b1c09db7c2efb635dede3 145 SUPERFAMILY SSF51230 66 142 7.85E-24 T 12-10-2018 IPR011053 Single hybrid motif THERU_04585 fd2b2eee0dd9cffba50ab2bfbd94f36e 308 SUPERFAMILY SSF56281 6 289 4.62E-62 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_04585 fd2b2eee0dd9cffba50ab2bfbd94f36e 308 Gene3D G3DSA:3.60.15.10 21 264 7.0E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_04585 fd2b2eee0dd9cffba50ab2bfbd94f36e 308 Pfam PF00753 Metallo-beta-lactamase superfamily 47 237 1.7E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_04585 fd2b2eee0dd9cffba50ab2bfbd94f36e 308 SMART SM00849 49 237 1.3E-29 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_05870 74d48e8e96a59ca8c64e3e8b35248797 80 Hamap MF_00262 Cell division topological specificity factor [minE]. 2 80 12.608 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THERU_05870 74d48e8e96a59ca8c64e3e8b35248797 80 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 2 79 3.6E-18 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THERU_05870 74d48e8e96a59ca8c64e3e8b35248797 80 SUPERFAMILY SSF55229 29 79 1.31E-7 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 THERU_05870 74d48e8e96a59ca8c64e3e8b35248797 80 Gene3D G3DSA:3.30.1070.10 1 79 1.7E-11 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 THERU_05870 74d48e8e96a59ca8c64e3e8b35248797 80 Pfam PF03776 Septum formation topological specificity factor MinE 12 79 4.8E-17 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 Hamap MF_01151 Protein GrpE [grpE]. 2 182 19.475 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 Gene3D G3DSA:2.30.22.10 126 181 1.6E-19 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 PRINTS PR00773 GrpE protein signature 82 97 3.1E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 PRINTS PR00773 GrpE protein signature 54 70 3.1E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 PRINTS PR00773 GrpE protein signature 161 180 3.1E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 PRINTS PR00773 GrpE protein signature 134 149 3.1E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 SUPERFAMILY SSF58014 31 126 1.44E-19 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 ProSitePatterns PS01071 grpE protein signature. 137 180 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 Pfam PF01025 GrpE 23 181 2.5E-46 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 SUPERFAMILY SSF51064 128 181 3.4E-15 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THERU_05635 9053cb8a37a559687aab093bb66a9a6f 188 Gene3D G3DSA:3.90.20.20 22 125 2.0E-19 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 164 41.054 T 12-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 TIGRFAM TIGR02084 leud: 3-isopropylmalate dehydratase, small subunit 5 160 3.6E-83 T 12-10-2018 IPR011824 Hydrolyase LeuD/DmdB, bacterial GO:0016836 KEGG: 00290+4.2.1.33 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 160 6.3E-65 T 12-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 Pfam PF00694 Aconitase C-terminal domain 39 101 5.3E-19 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 Gene3D G3DSA:3.20.19.10 1 168 3.4E-63 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 THERU_07085 91a1ba2571f4f0962fcc614eb42dd112 169 SUPERFAMILY SSF52016 3 163 1.06E-51 T 12-10-2018 THERU_01950 d193fb8296b095d6f03427368af368fa 330 Gene3D G3DSA:3.30.565.10 205 325 8.0E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_01950 d193fb8296b095d6f03427368af368fa 330 Pfam PF06580 Histidine kinase 153 226 3.7E-22 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 THERU_01950 d193fb8296b095d6f03427368af368fa 330 SUPERFAMILY SSF55874 226 323 1.06E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 Pfam PF01957 NfeD-like C-terminal, partner-binding 280 418 4.7E-33 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 SUPERFAMILY SSF52096 17 181 6.04E-27 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 SUPERFAMILY SSF141322 351 418 5.89E-13 T 12-10-2018 THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 Gene3D G3DSA:3.90.226.10 13 231 1.5E-61 T 12-10-2018 THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 Gene3D G3DSA:2.40.50.140 355 419 2.4E-16 T 12-10-2018 THERU_00855 72b3d5cfec2bab7241eddba690ad6814 419 Pfam PF00574 Clp protease 51 181 7.4E-8 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THERU_03435 c394f45eedccc394087219510495201e 184 SUPERFAMILY SSF117457 3 173 1.31E-64 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 THERU_03435 c394f45eedccc394087219510495201e 184 Pfam PF05683 Fumarase C-terminus 5 174 2.1E-58 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THERU_03435 c394f45eedccc394087219510495201e 184 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 174 3.9E-52 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THERU_03435 c394f45eedccc394087219510495201e 184 Gene3D G3DSA:3.20.130.10 1 174 2.1E-69 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 241 1.3E-103 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 Gene3D G3DSA:3.40.50.720 1 242 9.2E-95 T 12-10-2018 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 9.0E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 182 3.1E-7 T 12-10-2018 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 SUPERFAMILY SSF51735 5 241 8.27E-94 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 PIRSF PIRSF000126 2 213 1.2E-51 T 12-10-2018 THERU_03355 7081970d7b6eb737f95d07b6d5e2aa63 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 6.0E-70 T 12-10-2018 THERU_02360 1b116fd746ccc0f2907bcd902206f31c 81 SUPERFAMILY SSF52833 7 76 8.09E-12 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02360 1b116fd746ccc0f2907bcd902206f31c 81 Pfam PF13192 Thioredoxin domain 3 78 1.5E-19 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_02360 1b116fd746ccc0f2907bcd902206f31c 81 Gene3D G3DSA:3.40.30.10 1 78 1.2E-17 T 12-10-2018 THERU_06085 02d8207600d3c48bb03e33bdcad6a6df 278 SUPERFAMILY SSF74653 170 273 9.94E-20 T 12-10-2018 THERU_06085 02d8207600d3c48bb03e33bdcad6a6df 278 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 203 276 2.7E-20 T 12-10-2018 IPR006260 TonB/TolA, C-terminal THERU_06085 02d8207600d3c48bb03e33bdcad6a6df 278 Gene3D G3DSA:3.30.1150.10 88 277 1.6E-25 T 12-10-2018 THERU_06085 02d8207600d3c48bb03e33bdcad6a6df 278 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 202 276 2.7E-22 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 ProSitePatterns PS00585 Ribosomal protein S5 signature. 45 77 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 27 177 9.0E-60 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 Pfam PF00333 Ribosomal protein S5, N-terminal domain 28 92 1.4E-25 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 SUPERFAMILY SSF54768 27 93 1.15E-20 T 12-10-2018 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 Gene3D G3DSA:3.30.230.10 91 184 5.1E-29 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 Gene3D G3DSA:3.30.160.20 21 90 1.6E-27 T 12-10-2018 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 6 180 32.472 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 SUPERFAMILY SSF54211 96 175 6.57E-25 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_01480 bd775a5b69aa1b4ebd0d733a9bb4ad04 191 Pfam PF03719 Ribosomal protein S5, C-terminal domain 104 174 5.6E-26 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 THERU_07745 cdd35ebd6cde8c204520c94e9d6fc8ae 76 Pfam PF12800 4Fe-4S binding domain 11 25 0.02 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_07745 cdd35ebd6cde8c204520c94e9d6fc8ae 76 Pfam PF12800 4Fe-4S binding domain 44 57 0.016 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_07745 cdd35ebd6cde8c204520c94e9d6fc8ae 76 SUPERFAMILY SSF54862 4 67 2.99E-11 T 12-10-2018 THERU_07745 cdd35ebd6cde8c204520c94e9d6fc8ae 76 Gene3D G3DSA:3.30.70.20 1 75 4.1E-10 T 12-10-2018 THERU_02345 8c023abe335e86e0e58f137a06e65822 303 Gene3D G3DSA:3.40.50.300 1 303 2.2E-86 T 12-10-2018 THERU_02345 8c023abe335e86e0e58f137a06e65822 303 Pfam PF00005 ABC transporter 28 173 8.1E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_02345 8c023abe335e86e0e58f137a06e65822 303 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_02345 8c023abe335e86e0e58f137a06e65822 303 SUPERFAMILY SSF52540 3 244 6.23E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02345 8c023abe335e86e0e58f137a06e65822 303 SMART SM00382 37 221 1.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_02345 8c023abe335e86e0e58f137a06e65822 303 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 223 284 1.8E-11 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THERU_02345 8c023abe335e86e0e58f137a06e65822 303 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 222 300 3.6E-10 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Gene3D G3DSA:1.10.1140.10 357 475 1.5E-56 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 84 5.6E-18 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 2.6E-65 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Gene3D G3DSA:2.40.10.170 2 86 1.5E-25 T 12-10-2018 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Hamap MF_01347 ATP synthase subunit beta [atpB]. 3 472 55.251 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 SUPERFAMILY SSF50615 4 86 2.15E-22 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 SUPERFAMILY SSF52540 88 358 3.12E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 SMART SM00382 153 331 1.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 5 472 1.4E-251 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 SUPERFAMILY SSF47917 357 472 7.59E-52 T 12-10-2018 THERU_03565 a1b41dffb3675c290100cec990b0aaae 476 Gene3D G3DSA:3.40.50.300 87 356 1.0E-111 T 12-10-2018 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 278 6.3E-146 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 Gene3D G3DSA:1.20.58.180 205 280 4.2E-33 T 12-10-2018 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 278 9.1E-152 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 Gene3D G3DSA:3.30.930.10 1 204 1.2E-112 T 12-10-2018 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 8.1E-67 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 280 58.132 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THERU_05395 8ffecc7060da219dd3055ed10ba16af8 280 SUPERFAMILY SSF55681 2 278 3.48E-130 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 Gene3D G3DSA:3.30.470.30 83 184 1.8E-71 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 SUPERFAMILY SSF56091 51 234 6.3E-36 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 Gene3D G3DSA:2.20.25.320 2 50 7.2E-23 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 Pfam PF09414 RNA ligase 73 228 5.4E-20 T 12-10-2018 IPR021122 RNA ligase domain, REL/Rln2 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 151 172 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 206 219 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 74 87 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 125 140 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 342 362 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 277 291 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 52 70 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 224 237 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 31 45 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 95 110 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 PRINTS PR01048 Hypothetical protein Y414 family signature 248 266 3.7E-67 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_01860 2e206ad4580d6b24e9d809c983949247 367 Gene3D G3DSA:3.30.70.2160 230 367 2.1E-46 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 Gene3D G3DSA:3.30.1490.70 58 229 1.8E-71 T 12-10-2018 THERU_01860 2e206ad4580d6b24e9d809c983949247 367 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 7 366 1.8E-122 T 12-10-2018 IPR001072 RNA ligase, Pab1020 family THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 Gene3D G3DSA:1.10.760.10 87 167 6.1E-32 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 SUPERFAMILY SSF46626 93 166 1.2E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 Pfam PF00034 Cytochrome c 89 167 5.6E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 PRINTS PR00606 Class ID cytochrome C signature 129 142 2.5E-23 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 PRINTS PR00606 Class ID cytochrome C signature 106 119 2.5E-23 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 PRINTS PR00606 Class ID cytochrome C signature 155 165 2.5E-23 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 PRINTS PR00606 Class ID cytochrome C signature 91 104 2.5E-23 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06170 6a3206850bca897c8ee8c12451a02e27 167 PRINTS PR00606 Class ID cytochrome C signature 144 154 2.5E-23 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 288 34.615 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 SUPERFAMILY SSF56059 94 287 5.72E-48 T 12-10-2018 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Gene3D G3DSA:3.30.470.20 83 287 3.9E-73 T 12-10-2018 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Gene3D G3DSA:3.30.1490.20 109 170 3.9E-73 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Gene3D G3DSA:3.40.50.20 1 82 8.3E-30 T 12-10-2018 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 2.7E-20 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 SUPERFAMILY SSF52440 2 94 2.21E-31 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 SMART SM01209 93 258 0.0019 T 12-10-2018 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 PIRSF PIRSF039102 1 52 2.6E-9 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 PIRSF PIRSF039102 42 288 1.9E-85 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 Pfam PF07478 D-ala D-ala ligase C-terminus 107 287 1.8E-53 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 233 261 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06205 44e7aac3c4d76742f2165c3b61b85e34 288 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 287 5.7E-94 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SUPERFAMILY SSF110997 317 387 3.79E-12 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 96 129 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 166 199 3.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 28 61 0.54 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 132 165 56.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 62 95 4.3E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SMART SM00028 200 233 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Gene3D G3DSA:1.25.40.10 20 126 3.1E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Pfam PF13432 Tetratricopeptide repeat 67 126 6.0E-7 T 12-10-2018 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Gene3D G3DSA:1.25.40.10 127 259 1.5E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Pfam PF13174 Tetratricopeptide repeat 167 195 0.0018 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Gene3D G3DSA:3.30.70.1070 312 389 1.6E-12 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 SUPERFAMILY SSF81901 30 234 2.62E-26 T 12-10-2018 THERU_05465 9e3d395836f1e7efa8bc610708724ea3 389 Pfam PF05036 Sporulation related domain 317 383 1.6E-12 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 321 1.4E-6 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 Gene3D G3DSA:1.10.8.60 8 239 1.2E-102 T 12-10-2018 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 SMART SM00382 37 179 1.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 329 2.7E-129 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 2.6E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 2.6E-5 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 27 191 6.1E-56 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 SUPERFAMILY SSF52540 30 221 7.41E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 Gene3D G3DSA:3.40.50.300 13 177 1.2E-102 T 12-10-2018 THERU_07545 d3729e71ce50aea7453f35e33a6a99ba 486 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.2E-49 T 12-10-2018 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 182 39.035 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 109 119 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 SUPERFAMILY SSF55620 3 183 3.71E-72 T 12-10-2018 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 182 1.1E-66 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 Gene3D G3DSA:1.10.286.10 1 44 9.8E-18 T 12-10-2018 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 Gene3D G3DSA:3.30.1130.10 51 184 7.0E-57 T 12-10-2018 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 Pfam PF01227 GTP cyclohydrolase I 9 181 8.4E-71 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THERU_07510 dc3c311ab7939a238a649af384c8fbbd 186 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 61 77 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THERU_06260 40bf4ae440249ad356f207de2c288706 335 SUPERFAMILY SSF55347 146 303 1.84E-43 T 12-10-2018 THERU_06260 40bf4ae440249ad356f207de2c288706 335 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 330 8.8E-116 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_06260 40bf4ae440249ad356f207de2c288706 335 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_06260 40bf4ae440249ad356f207de2c288706 335 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 329 39.277 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_06260 40bf4ae440249ad356f207de2c288706 335 SUPERFAMILY SSF51735 1 159 1.23E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06260 40bf4ae440249ad356f207de2c288706 335 SMART SM00859 2 138 3.9E-56 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THERU_06260 40bf4ae440249ad356f207de2c288706 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 137 3.4E-33 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THERU_06260 40bf4ae440249ad356f207de2c288706 335 Gene3D G3DSA:3.30.360.10 144 303 2.4E-113 T 12-10-2018 THERU_06260 40bf4ae440249ad356f207de2c288706 335 Gene3D G3DSA:3.40.50.720 2 321 2.4E-113 T 12-10-2018 THERU_06260 40bf4ae440249ad356f207de2c288706 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 304 3.4E-13 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Gene3D G3DSA:3.30.1490.110 79 165 1.7E-105 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Pfam PF02491 SHS2 domain inserted in FTSA 82 157 8.1E-21 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Gene3D G3DSA:3.90.640.10 231 296 1.7E-105 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 4 374 1.0E-120 T 12-10-2018 IPR020823 Cell division protein FtsA THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 SUPERFAMILY SSF53067 195 373 2.16E-41 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Gene3D G3DSA:3.30.420.40 193 349 1.7E-105 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Pfam PF14450 Cell division protein FtsA 5 173 8.2E-8 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 415 25.431 T 12-10-2018 IPR020823 Cell division protein FtsA THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Pfam PF14450 Cell division protein FtsA 204 371 1.9E-22 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 SMART SM00842 4 192 1.7E-67 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 Gene3D G3DSA:3.30.420.40 7 369 1.7E-105 T 12-10-2018 THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 PIRSF PIRSF003101 1 415 4.8E-121 T 12-10-2018 IPR020823 Cell division protein FtsA THERU_06215 b89882b2b4c99bdcb0e4e3390c7c0f6c 415 SUPERFAMILY SSF53067 3 193 3.89E-41 T 12-10-2018 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 1.3E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 PRINTS PR00813 Bacterial general secretion pathway protein G signature 40 58 5.3E-17 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 PRINTS PR00813 Bacterial general secretion pathway protein G signature 4 29 5.3E-17 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 3 131 1.7E-53 T 12-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 Gene3D G3DSA:3.30.700.10 18 131 3.6E-36 T 12-10-2018 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 SUPERFAMILY SSF54523 30 128 9.42E-33 T 12-10-2018 THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 1.3E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_06470 5e79601c79e2b06b6935430748d6d0c9 133 Pfam PF08334 Type II secretion system (T2SS), protein G 27 130 2.2E-34 T 12-10-2018 IPR013545 Type II secretion system protein G THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Pfam PF12804 MobA-like NTP transferase domain 3 117 9.6E-20 T 12-10-2018 IPR025877 MobA-like NTP transferase THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Gene3D G3DSA:2.160.10.10 260 447 2.9E-53 T 12-10-2018 THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 SUPERFAMILY SSF53448 1 253 1.49E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 459 34.821 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 410 438 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Gene3D G3DSA:3.90.550.10 1 258 1.6E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 325 358 1.3E-7 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 361 392 0.0014 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 402 436 4.0E-6 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 273 306 1.2E-6 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 459 3.6E-162 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 THERU_05800 6181d1c0ed2f83c6fe7457f68c056713 462 SUPERFAMILY SSF51161 262 444 1.18E-44 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily THERU_08330 ab870abbf4f1ebe40335ffcff6eaae1c 277 Gene3D G3DSA:3.40.50.300 20 254 4.2E-49 T 12-10-2018 THERU_08330 ab870abbf4f1ebe40335ffcff6eaae1c 277 PIRSF PIRSF003092 3 265 1.1E-56 T 12-10-2018 IPR025501 ATP binding protein MinD THERU_08330 ab870abbf4f1ebe40335ffcff6eaae1c 277 SUPERFAMILY SSF52540 21 242 5.24E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08330 ab870abbf4f1ebe40335ffcff6eaae1c 277 Pfam PF13614 AAA domain 21 178 7.0E-19 T 12-10-2018 IPR025669 AAA domain THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 Gene3D G3DSA:3.40.50.300 292 565 3.3E-114 T 12-10-2018 THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 SUPERFAMILY SSF160246 5 142 1.15E-23 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 SMART SM00382 315 438 4.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 SUPERFAMILY SSF52540 170 563 4.67E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 Gene3D G3DSA:3.30.450.90 146 286 1.2E-46 T 12-10-2018 THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 38 145 1.1E-14 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 382 396 - T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 Pfam PF00437 Type II/IV secretion system protein 189 454 1.5E-83 T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_04500 2f41f568a6eceea41a38d27de61b5603 566 Gene3D G3DSA:3.30.300.160 65 143 3.3E-9 T 12-10-2018 THERU_03785 76307dd662fc6797c59d56d00027eb40 223 Gene3D G3DSA:1.10.3720.10 2 222 9.2E-52 T 12-10-2018 IPR035906 MetI-like superfamily THERU_03785 76307dd662fc6797c59d56d00027eb40 223 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 219 2.8E-73 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 THERU_03785 76307dd662fc6797c59d56d00027eb40 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 220 1.2E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_03785 76307dd662fc6797c59d56d00027eb40 223 SUPERFAMILY SSF161098 6 215 8.5E-49 T 12-10-2018 IPR035906 MetI-like superfamily THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 SUPERFAMILY SSF141868 180 408 1.09E-49 T 12-10-2018 IPR035919 EAL domain superfamily THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 Gene3D G3DSA:3.30.70.270 13 168 1.8E-25 T 12-10-2018 THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 Pfam PF00990 Diguanylate cyclase, GGDEF domain 15 158 3.7E-20 T 12-10-2018 IPR000160 GGDEF domain THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 SMART SM00052 173 411 2.1E-17 T 12-10-2018 IPR001633 EAL domain THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 SMART SM00267 2 164 2.5E-7 T 12-10-2018 IPR000160 GGDEF domain THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 Pfam PF00563 EAL domain 182 407 3.9E-45 T 12-10-2018 IPR001633 EAL domain THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 15 159 3.2E-21 T 12-10-2018 IPR000160 GGDEF domain THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 Gene3D G3DSA:3.20.20.450 173 411 3.6E-51 T 12-10-2018 IPR035919 EAL domain superfamily THERU_05990 6b5ad9a7a48f38ed8e65b7b3a27c1926 411 SUPERFAMILY SSF55073 15 163 2.9E-23 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_03810 aa83a8078311ce6071f4974e1dd94ab7 149 Gene3D G3DSA:3.40.630.30 3 147 2.0E-38 T 12-10-2018 THERU_03810 aa83a8078311ce6071f4974e1dd94ab7 149 Pfam PF00583 Acetyltransferase (GNAT) family 18 123 8.4E-18 T 12-10-2018 IPR000182 GNAT domain THERU_03810 aa83a8078311ce6071f4974e1dd94ab7 149 SUPERFAMILY SSF55729 3 146 2.78E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase THERU_03810 aa83a8078311ce6071f4974e1dd94ab7 149 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 13 142 9.6E-32 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 6 101 5.3E-43 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 SUPERFAMILY SSF54999 5 102 3.79E-36 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 SMART SM01403 7 101 6.1E-49 T 12-10-2018 IPR027486 Ribosomal protein S10 domain THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 Gene3D G3DSA:3.30.70.600 1 103 2.0E-35 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 3.4E-34 T 12-10-2018 IPR027486 Ribosomal protein S10 domain THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.5E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.5E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.5E-18 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07330 6f75ba0e5fa8dbddcdf20cbfcc67e5fa 104 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.423 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_02710 2f88f8cd0916bf36ace3ab0ae2c8e661 167 SUPERFAMILY SSF54197 1 151 6.96E-34 T 12-10-2018 IPR036265 HIT-like superfamily THERU_02710 2f88f8cd0916bf36ace3ab0ae2c8e661 167 Gene3D G3DSA:3.30.428.10 1 165 1.6E-44 T 12-10-2018 IPR036265 HIT-like superfamily THERU_02710 2f88f8cd0916bf36ace3ab0ae2c8e661 167 Pfam PF01230 HIT domain 37 128 5.3E-7 T 12-10-2018 IPR001310 Histidine triad (HIT) protein THERU_07045 8b9cab1ff76364ee128cee0fbeeec11e 224 Pfam PF00117 Glutamine amidotransferase class-I 17 177 5.2E-20 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_07045 8b9cab1ff76364ee128cee0fbeeec11e 224 Gene3D G3DSA:3.40.50.880 1 224 6.9E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_07045 8b9cab1ff76364ee128cee0fbeeec11e 224 SUPERFAMILY SSF52317 38 197 4.87E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 SUPERFAMILY SSF103025 1 254 1.43E-81 T 12-10-2018 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 248 333 3.4E-20 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Gene3D G3DSA:4.10.1250.10 221 259 1.4E-10 T 12-10-2018 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 241 5.4E-78 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 PIRSF PIRSF006487 1 340 6.1E-81 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Gene3D G3DSA:2.40.30.110 260 340 3.2E-24 T 12-10-2018 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 340 5.0E-93 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Gene3D G3DSA:3.30.1360.120 4 219 3.3E-71 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 Gene3D G3DSA:3.30.70.1400 50 132 3.3E-71 T 12-10-2018 THERU_04560 a98e1ec07ac5d744d4f5447a8511737d 340 SUPERFAMILY SSF101790 257 340 4.41E-21 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal THERU_01710 21c9c3b650b24688e21c861728c6437b 167 SUPERFAMILY SSF75169 42 165 9.42E-25 T 12-10-2018 IPR027396 DsrEFH-like THERU_01710 21c9c3b650b24688e21c861728c6437b 167 Pfam PF02635 DsrE/DsrF-like family 43 165 2.9E-13 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_01710 21c9c3b650b24688e21c861728c6437b 167 Gene3D G3DSA:3.40.1260.10 39 165 4.9E-25 T 12-10-2018 IPR027396 DsrEFH-like THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 119 203 1.7E-14 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 SUPERFAMILY SSF101386 116 204 1.83E-22 T 12-10-2018 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 2 205 34.603 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 119 200 6.6E-27 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 49 99 5.0E-20 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 26 100 3.3E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Gene3D G3DSA:3.10.20.400 1 91 9.3E-36 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 114 200 18.197 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 104 29.385 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 SUPERFAMILY SSF141734 3 108 6.15E-43 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 THERU_07885 0cd6ada2c53699684c2203a46694aaa8 206 Gene3D G3DSA:1.10.287.1080 115 206 1.2E-25 T 12-10-2018 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 SMART SM01340 208 307 1.2E-6 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 Gene3D G3DSA:2.30.42.20 324 424 6.7E-30 T 12-10-2018 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 SUPERFAMILY SSF54211 191 307 3.64E-15 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_05180 d355a9bb6045de0a58db868dc457769e 424 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site THERU_05180 d355a9bb6045de0a58db868dc457769e 424 SUPERFAMILY SSF118116 331 421 2.48E-11 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily THERU_05180 d355a9bb6045de0a58db868dc457769e 424 Gene3D G3DSA:3.30.565.10 1 209 1.9E-64 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_05180 d355a9bb6045de0a58db868dc457769e 424 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 113 1.1E-11 T 12-10-2018 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 2 290 1.2E-82 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 224 305 1.0E-11 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 THERU_05180 d355a9bb6045de0a58db868dc457769e 424 Gene3D G3DSA:3.30.230.10 210 307 8.1E-12 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_05180 d355a9bb6045de0a58db868dc457769e 424 SUPERFAMILY SSF55874 4 213 1.31E-49 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_02550 3c5baccb7f2f6bb2689353b39e3dfd43 79 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.2E-30 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_02550 3c5baccb7f2f6bb2689353b39e3dfd43 79 Gene3D G3DSA:3.30.1320.10 1 79 1.1E-32 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_02550 3c5baccb7f2f6bb2689353b39e3dfd43 79 SUPERFAMILY SSF54565 3 78 3.92E-28 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_02550 3c5baccb7f2f6bb2689353b39e3dfd43 79 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 76 22.201 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_02550 3c5baccb7f2f6bb2689353b39e3dfd43 79 Pfam PF00886 Ribosomal protein S16 9 66 2.5E-20 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 Gene3D G3DSA:3.30.70.240 1 93 6.7E-23 T 12-10-2018 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 85 2.3E-14 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 93 14.661 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 SUPERFAMILY SSF143430 1 83 8.24E-22 T 12-10-2018 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 PIRSF PIRSF032582 1 91 5.1E-21 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THERU_04470 b38ecace4c3d19942ddf91432abb9d85 93 Pfam PF09827 CRISPR associated protein Cas2 1 77 1.2E-20 T 12-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THERU_03315 1f9f5df76295b8df083d30468cb62523 361 SUPERFAMILY SSF53756 1 293 1.81E-16 T 12-10-2018 THERU_03315 1f9f5df76295b8df083d30468cb62523 361 Pfam PF02684 Lipid-A-disaccharide synthetase 3 316 1.0E-88 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 THERU_03315 1f9f5df76295b8df083d30468cb62523 361 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 16 314 1.4E-63 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 SMART SM00926 1 49 9.7E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 SUPERFAMILY SSF50692 525 653 7.69E-30 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 SUPERFAMILY SSF53706 5 540 4.45E-168 T 12-10-2018 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Pfam PF01568 Molydopterin dinucleotide binding domain 547 647 1.7E-27 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Gene3D G3DSA:3.40.228.10 127 325 1.5E-162 T 12-10-2018 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Gene3D G3DSA:2.20.25.90 3 50 2.5E-5 T 12-10-2018 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Pfam PF00384 Molybdopterin oxidoreductase 51 471 3.9E-69 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Gene3D G3DSA:2.40.40.20 541 655 3.8E-29 T 12-10-2018 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 39 2.2E-9 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04670 831f1bb733b136462acf618ffc2c23b5 656 Gene3D G3DSA:3.40.50.740 56 516 1.5E-162 T 12-10-2018 THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 SUPERFAMILY SSF57716 84 117 2.71E-10 T 12-10-2018 THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 SUPERFAMILY SSF109635 3 83 3.27E-16 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 87 111 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 Gene3D G3DSA:1.20.120.910 1 121 1.6E-31 T 12-10-2018 THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 82 116 1.7E-13 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 PRINTS PR00618 DksA/TraR zinc finger signature 87 98 8.2E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THERU_02235 ab1aaddb6953f5d19ac8fc73baaf6a85 121 PRINTS PR00618 DksA/TraR zinc finger signature 99 111 8.2E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THERU_07075 3dc7f7fea489f3a83a958dc57c8700c9 243 Pfam PF02535 ZIP Zinc transporter 104 238 6.9E-15 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 THERU_07385 3a53b98e7da10d541d8f0245a345f4ec 113 SUPERFAMILY SSF75169 2 113 2.88E-18 T 12-10-2018 IPR027396 DsrEFH-like THERU_07385 3a53b98e7da10d541d8f0245a345f4ec 113 Gene3D G3DSA:3.40.1260.10 1 113 1.3E-18 T 12-10-2018 IPR027396 DsrEFH-like THERU_07385 3a53b98e7da10d541d8f0245a345f4ec 113 Pfam PF02635 DsrE/DsrF-like family 1 112 2.0E-14 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_07470 23554d86ddfc2d7b5d121e05b2b2fdfb 131 Gene3D G3DSA:3.60.90.10 1 131 1.0E-51 T 12-10-2018 THERU_07470 23554d86ddfc2d7b5d121e05b2b2fdfb 131 SUPERFAMILY SSF56276 4 116 1.0E-39 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 THERU_07470 23554d86ddfc2d7b5d121e05b2b2fdfb 131 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 2 118 30.429 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THERU_07470 23554d86ddfc2d7b5d121e05b2b2fdfb 131 Pfam PF02675 S-adenosylmethionine decarboxylase 8 114 4.6E-37 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THERU_07470 23554d86ddfc2d7b5d121e05b2b2fdfb 131 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 4 114 4.6E-41 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THERU_00415 195804114d5a0d7f0b04b9eba6cbc270 304 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 8 228 4.3E-39 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD THERU_00415 195804114d5a0d7f0b04b9eba6cbc270 304 Pfam PF13525 Outer membrane lipoprotein 34 227 2.7E-36 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like THERU_00415 195804114d5a0d7f0b04b9eba6cbc270 304 Gene3D G3DSA:1.25.40.10 23 279 3.4E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00415 195804114d5a0d7f0b04b9eba6cbc270 304 SUPERFAMILY SSF48452 37 124 1.46E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 22 313 6.6E-61 T 12-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 Pfam PF01544 CorA-like Mg2+ transporter protein 27 309 2.9E-63 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 Gene3D G3DSA:1.20.58.340 256 313 1.3E-22 T 12-10-2018 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 Gene3D G3DSA:3.30.460.20 2 130 8.3E-10 T 12-10-2018 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 Gene3D G3DSA:1.20.58.340 132 254 7.7E-6 T 12-10-2018 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 SUPERFAMILY SSF143865 1 250 1.44E-32 T 12-10-2018 THERU_04230 7d109cc7163fcc451e0a9615fbc4f803 313 SUPERFAMILY SSF144083 248 311 3.27E-22 T 12-10-2018 THERU_04130 2965ebc13888828f278e799423123c09 220 Gene3D G3DSA:3.90.870.10 2 199 5.0E-44 T 12-10-2018 THERU_04130 2965ebc13888828f278e799423123c09 220 Pfam PF01300 Telomere recombination 14 186 1.9E-33 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 THERU_04130 2965ebc13888828f278e799423123c09 220 SUPERFAMILY SSF55821 8 191 2.23E-37 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THERU_04130 2965ebc13888828f278e799423123c09 220 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 5 192 1.3E-42 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Hamap MF_01397 NADH-quinone oxidoreductase subunit C/D [nuoC]. 26 571 49.608 T 12-10-2018 IPR026662 NADH-quinone oxidoreductase subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 311 571 1.3E-98 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Gene3D G3DSA:1.10.645.20 194 571 2.4E-144 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Gene3D G3DSA:3.30.460.80 4 125 1.6E-24 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 146 3.0E-32 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 81 125 1.0E-16 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 SUPERFAMILY SSF143243 12 209 3.79E-44 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 179 571 44.193 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02495 7d056950d378ec83d5b6546ba2ab8e6e 571 SUPERFAMILY SSF56762 205 571 1.96E-116 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 Gene3D G3DSA:3.40.50.720 1 159 1.5E-46 T 12-10-2018 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 161 323 2.1E-30 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 157 3.7E-36 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 PRINTS PR00086 L-lactate dehydrogenase signature 131 151 8.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 PRINTS PR00086 L-lactate dehydrogenase signature 185 198 8.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 8.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 PRINTS PR00086 L-lactate dehydrogenase signature 155 173 8.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 SUPERFAMILY SSF51735 7 158 6.77E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 PIRSF PIRSF000102 1 330 1.0E-103 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 Gene3D G3DSA:3.90.110.10 160 331 4.0E-59 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 SUPERFAMILY SSF56327 158 323 5.77E-50 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THERU_05285 d1adc121d6a0d08391fca64c280bfb88 332 Hamap MF_00487 Malate dehydrogenase [mdh]. 5 325 40.639 T 12-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 Pfam PF02441 Flavoprotein 3 169 2.0E-46 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 SUPERFAMILY SSF102645 176 386 1.44E-60 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 178 348 4.6E-55 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 SUPERFAMILY SSF52507 3 169 3.4E-56 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 Gene3D G3DSA:3.40.50.10300 175 389 2.1E-62 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 Gene3D G3DSA:3.40.50.1950 1 174 4.6E-61 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THERU_01630 a7f2b3ed9d8a4a1c95fbb5a905d08731 389 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 383 2.3E-113 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 SUPERFAMILY SSF46946 2 123 3.53E-46 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 Gene3D G3DSA:1.10.8.50 1 72 7.6E-30 T 12-10-2018 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 PIRSF PIRSF002134 1 125 1.5E-46 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.0E-53 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 Gene3D G3DSA:4.10.910.10 73 126 1.1E-26 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 4.7E-33 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01520 ccd584eb8099ef741326c1248bd30413 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.111 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Gene3D G3DSA:2.40.50.140 67 130 9.4E-19 T 12-10-2018 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Gene3D G3DSA:2.30.30.30 3 65 2.3E-24 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 SMART SM01185 70 124 1.2E-17 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 SUPERFAMILY SSF50249 71 129 4.8E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 SMART SM00841 132 187 8.0E-36 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Gene3D G3DSA:2.40.50.140 131 189 3.8E-29 T 12-10-2018 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Pfam PF09285 Elongation factor P, C-terminal 132 187 3.2E-28 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 73 124 5.7E-18 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 TIGRFAM TIGR00038 efp: translation elongation factor P 6 188 2.8E-73 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 7 62 2.1E-24 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 SUPERFAMILY SSF50104 5 66 9.63E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 SUPERFAMILY SSF50249 131 188 6.28E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 Hamap MF_00141 Elongation factor P [efp]. 4 188 48.836 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THERU_07950 98651cad69c6f49e2d22b814cf4e5d77 189 PIRSF PIRSF005901 3 189 7.8E-70 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP THERU_03135 e1fa0cab3acf9b737e604385f049c70c 255 SMART SM00028 210 243 0.0044 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03135 e1fa0cab3acf9b737e604385f049c70c 255 Pfam PF13432 Tetratricopeptide repeat 135 190 3.8E-7 T 12-10-2018 THERU_03135 e1fa0cab3acf9b737e604385f049c70c 255 SUPERFAMILY SSF48452 128 246 5.87E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03135 e1fa0cab3acf9b737e604385f049c70c 255 Pfam PF13174 Tetratricopeptide repeat 212 243 5.3E-7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03135 e1fa0cab3acf9b737e604385f049c70c 255 Gene3D G3DSA:1.25.40.10 131 255 3.8E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06475 32d39ca4eaa260419968abd698fc62db 93 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 27 1.3E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_06475 32d39ca4eaa260419968abd698fc62db 93 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 4.5E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_03270 85c5a517b2b7cd715ae16e17d24a5b43 256 Pfam PF01975 Survival protein SurE 5 186 2.4E-59 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THERU_03270 85c5a517b2b7cd715ae16e17d24a5b43 256 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 253 37.636 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THERU_03270 85c5a517b2b7cd715ae16e17d24a5b43 256 SUPERFAMILY SSF64167 4 248 4.45E-80 T 12-10-2018 THERU_03270 85c5a517b2b7cd715ae16e17d24a5b43 256 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 4 236 2.5E-66 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THERU_03270 85c5a517b2b7cd715ae16e17d24a5b43 256 Gene3D G3DSA:3.40.1210.10 1 250 2.6E-94 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THERU_05585 25312d089a73e900b33822918193dad9 86 Pfam PF04977 Septum formation initiator 7 81 1.2E-11 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 77 8.5E-26 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 Pfam PF01455 HupF/HypC family 1 67 2.5E-26 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.2E-16 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 2.2E-16 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 2.2E-16 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 2.2E-16 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 SUPERFAMILY SSF159127 1 77 6.15E-26 T 12-10-2018 IPR037254 HupF/HypC superfamily THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 12-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site THERU_04795 684d51822fa2a7a6f7e69f72fd43a9f1 80 Gene3D G3DSA:2.40.50.970 1 79 4.9E-29 T 12-10-2018 IPR037254 HupF/HypC superfamily THERU_06620 a7ee3099c8875e89776547330f097560 149 SUPERFAMILY SSF82861 2 42 3.4E-7 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THERU_06620 a7ee3099c8875e89776547330f097560 149 Pfam PF00924 Mechanosensitive ion channel 2 140 1.8E-38 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THERU_06620 a7ee3099c8875e89776547330f097560 149 SUPERFAMILY SSF50182 44 109 6.87E-17 T 12-10-2018 IPR010920 LSM domain superfamily THERU_06620 a7ee3099c8875e89776547330f097560 149 Gene3D G3DSA:2.30.30.60 60 109 7.0E-13 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 Gene3D G3DSA:3.50.50.60 13 310 5.2E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 302 6.8E-34 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 13 313 8.1E-108 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 SUPERFAMILY SSF51905 10 314 2.65E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 14 36 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 47 62 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 1.1E-50 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 Gene3D G3DSA:3.50.50.60 125 247 5.2E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.3E-24 T 12-10-2018 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 2.3E-24 T 12-10-2018 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 2.3E-24 T 12-10-2018 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.3E-24 T 12-10-2018 THERU_05175 cd0e777ca27166d392f3e52103dd75c2 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.3E-24 T 12-10-2018 THERU_07775 e5f2e28024a5893506590e01128ddfd1 393 Gene3D G3DSA:3.40.50.150 109 377 1.2E-90 T 12-10-2018 THERU_07775 e5f2e28024a5893506590e01128ddfd1 393 Pfam PF02353 Mycolic acid cyclopropane synthetase 106 369 3.5E-100 T 12-10-2018 THERU_07775 e5f2e28024a5893506590e01128ddfd1 393 SUPERFAMILY SSF53335 110 373 3.58E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07775 e5f2e28024a5893506590e01128ddfd1 393 PIRSF PIRSF003085 2 389 2.3E-119 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 2 616 35.138 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Gene3D G3DSA:3.30.420.40 181 364 8.0E-151 T 12-10-2018 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 8 15 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 SUPERFAMILY SSF53067 5 185 5.02E-60 T 12-10-2018 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Pfam PF00012 Hsp70 protein 5 602 2.9E-243 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Gene3D G3DSA:3.90.640.10 225 314 8.0E-151 T 12-10-2018 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Gene3D G3DSA:2.60.34.10 375 559 8.0E-80 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 SUPERFAMILY SSF100920 382 538 8.5E-62 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 198 208 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 4 17 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 386 405 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 32 44 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 332 348 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 363 383 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 467 483 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 139 159 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 PRINTS PR00301 70kDa heat shock protein signature 55 63 6.5E-70 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 Gene3D G3DSA:3.30.420.40 6 374 8.0E-151 T 12-10-2018 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 SUPERFAMILY SSF53067 189 380 6.48E-65 T 12-10-2018 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THERU_01435 6077487a7d5e389d12f45d57ce70621a 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 599 7.0E-270 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SMART SM00357 63 129 1.0E-16 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SUPERFAMILY SSF68912 13 56 2.82E-8 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Gene3D G3DSA:2.40.50.140 11 138 8.4E-43 T 12-10-2018 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 169 375 9.6E-24 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 430 215.093 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Pfam PF07498 Rho termination factor, N-terminal domain 16 55 8.8E-11 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SUPERFAMILY SSF50249 62 136 6.28E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 TIGRFAM TIGR00767 rho: transcription termination factor Rho 14 429 5.8E-203 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Gene3D G3DSA:3.40.50.300 144 429 4.1E-125 T 12-10-2018 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 Pfam PF07497 Rho termination factor, RNA-binding domain 62 136 3.6E-29 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SMART SM00959 16 58 2.3E-9 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SUPERFAMILY SSF52540 139 383 7.58E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00375 2235a9c497ca6b85cc81ba8f37c92056 430 SMART SM00382 180 367 9.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03500 1a0826bdc141ed01d7f5c25aef21f65f 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 172 3.7E-18 T 12-10-2018 THERU_03500 1a0826bdc141ed01d7f5c25aef21f65f 221 Gene3D G3DSA:1.10.150.240 12 81 3.7E-21 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THERU_03500 1a0826bdc141ed01d7f5c25aef21f65f 221 Gene3D G3DSA:3.40.50.1000 1 172 3.7E-21 T 12-10-2018 IPR023214 HAD superfamily THERU_03500 1a0826bdc141ed01d7f5c25aef21f65f 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 174 7.0E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_03500 1a0826bdc141ed01d7f5c25aef21f65f 221 SUPERFAMILY SSF56784 1 175 3.62E-25 T 12-10-2018 IPR036412 HAD-like superfamily THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 Gene3D G3DSA:3.40.50.300 2 243 3.2E-64 T 12-10-2018 THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 20 249 9.4E-104 T 12-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 SMART SM00382 29 211 1.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 SUPERFAMILY SSF52540 5 221 5.96E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_04665 8f402ae85a30f55ace296cdee38c9d38 257 Pfam PF00005 ABC transporter 20 161 1.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 297 72.545 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 SUPERFAMILY SSF56176 9 186 7.36E-38 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Pfam PF01565 FAD binding domain 22 149 2.0E-19 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 284 3.3E-70 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Gene3D G3DSA:3.30.465.10 77 201 4.1E-29 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 SUPERFAMILY SSF56194 186 286 2.35E-33 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 186 284 9.8E-30 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Gene3D G3DSA:3.90.78.10 202 291 1.5E-32 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_06200 f0c097935e118972de73be8b1c4d8d1b 297 Gene3D G3DSA:3.30.43.10 1 71 7.1E-19 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 SUPERFAMILY SSF50249 1 140 3.08E-35 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 PIRSF PIRSF002070 1 137 3.1E-28 T 12-10-2018 THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 Gene3D G3DSA:2.40.50.140 1 121 7.7E-33 T 12-10-2018 THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 Hamap MF_00984 Single-stranded DNA-binding protein. 2 108 27.84 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 Pfam PF00436 Single-strand binding protein family 2 102 3.7E-28 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 THERU_07875 68154b19ada593bf0f8f0fc7215243f3 140 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 107 1.3E-34 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THERU_00945 5d8375213693aa455fa0690352aaa39c 227 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 2 210 1.9E-66 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THERU_00945 5d8375213693aa455fa0690352aaa39c 227 PIRSF PIRSF003107 1 216 1.3E-66 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THERU_00945 5d8375213693aa455fa0690352aaa39c 227 Gene3D G3DSA:1.20.58.220 1 105 4.6E-41 T 12-10-2018 IPR038078 PhoU-like domain superfamily THERU_00945 5d8375213693aa455fa0690352aaa39c 227 SUPERFAMILY SSF109755 3 216 1.99E-71 T 12-10-2018 THERU_00945 5d8375213693aa455fa0690352aaa39c 227 Gene3D G3DSA:1.20.58.220 106 221 5.2E-45 T 12-10-2018 IPR038078 PhoU-like domain superfamily THERU_00945 5d8375213693aa455fa0690352aaa39c 227 Pfam PF01895 PhoU domain 118 201 4.5E-23 T 12-10-2018 IPR026022 PhoU domain THERU_00945 5d8375213693aa455fa0690352aaa39c 227 Pfam PF01895 PhoU domain 15 101 7.3E-25 T 12-10-2018 IPR026022 PhoU domain THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 3 302 3.0E-124 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 Gene3D G3DSA:2.30.26.10 54 215 7.7E-91 T 12-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 SUPERFAMILY SSF51395 1 292 2.53E-79 T 12-10-2018 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 39 58 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 Pfam PF01180 Dihydroorotate dehydrogenase 3 287 8.1E-69 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 PIRSF PIRSF000164 1 303 1.0E-80 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 Gene3D G3DSA:3.20.20.70 11 291 7.7E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 240 260 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THERU_07900 dc5cf51e9eaa07a1aa01c0d6fb20615a 312 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 3 301 38.874 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Gene3D G3DSA:1.10.10.1600 445 544 2.7E-18 T 12-10-2018 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 SUPERFAMILY SSF89550 4 262 1.55E-35 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1023 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Gene3D G3DSA:1.10.150.870 804 905 1.0E-11 T 12-10-2018 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 309 758 1.6E-174 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Gene3D G3DSA:3.20.20.140 1 285 8.0E-99 T 12-10-2018 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Pfam PF14579 Helix-hairpin-helix motif 832 917 1.3E-27 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Pfam PF02811 PHP domain 6 181 5.7E-48 T 12-10-2018 IPR004013 PHP domain GO:0003824 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 Gene3D G3DSA:2.40.50.140 969 1066 2.3E-5 T 12-10-2018 THERU_00605 0daa0839f4e249e0df220cf0c1ac43bf 1149 SMART SM00481 5 72 2.3E-31 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 PRINTS PR00625 DnaJ domain signature 7 25 5.3E-26 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 PRINTS PR00625 DnaJ domain signature 61 80 5.3E-26 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 PRINTS PR00625 DnaJ domain signature 25 40 5.3E-26 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 PRINTS PR00625 DnaJ domain signature 41 61 5.3E-26 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 SUPERFAMILY SSF49493 244 324 5.36E-13 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 SUPERFAMILY SSF49493 101 252 9.16E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 SUPERFAMILY SSF57938 121 195 1.96E-14 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Gene3D G3DSA:2.60.260.20 239 340 1.6E-20 T 12-10-2018 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Gene3D G3DSA:2.60.260.20 104 234 2.2E-30 T 12-10-2018 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Pfam PF00226 DnaJ domain 5 66 1.5E-28 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Gene3D G3DSA:2.10.230.10 134 192 2.2E-30 T 12-10-2018 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 SMART SM00271 4 61 7.5E-32 T 12-10-2018 IPR001623 DnaJ domain THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Gene3D G3DSA:1.10.287.110 2 101 1.2E-34 T 12-10-2018 IPR036869 Chaperone J-domain superfamily THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Pfam PF01556 DnaJ C terminal domain 107 314 2.4E-30 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 350 32.155 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THERU_07735 ee72f4569d5fea8e2ea300af4ed333ed 352 SUPERFAMILY SSF46565 1 82 4.32E-33 T 12-10-2018 IPR036869 Chaperone J-domain superfamily THERU_00205 011ce9ab7fcfc820e38ef057621c6777 129 SUPERFAMILY SSF75169 2 129 9.42E-21 T 12-10-2018 IPR027396 DsrEFH-like THERU_00205 011ce9ab7fcfc820e38ef057621c6777 129 Gene3D G3DSA:3.40.1260.10 1 129 3.1E-33 T 12-10-2018 IPR027396 DsrEFH-like THERU_00205 011ce9ab7fcfc820e38ef057621c6777 129 Pfam PF02635 DsrE/DsrF-like family 2 129 5.9E-18 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_00550 72e53e50064a67f65482656683daf106 229 Gene3D G3DSA:3.40.470.10 30 228 3.0E-69 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THERU_00550 72e53e50064a67f65482656683daf106 229 SMART SM00986 71 220 1.5E-35 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THERU_00550 72e53e50064a67f65482656683daf106 229 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 58 227 1.3E-65 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 THERU_00550 72e53e50064a67f65482656683daf106 229 SMART SM00987 71 220 1.5E-35 T 12-10-2018 THERU_00550 72e53e50064a67f65482656683daf106 229 SUPERFAMILY SSF52141 45 226 2.16E-57 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THERU_00550 72e53e50064a67f65482656683daf106 229 Pfam PF03167 Uracil DNA glycosylase superfamily 71 220 1.1E-45 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THERU_08465 cdfe501b0479f8a3124cdde998d81551 173 Gene3D G3DSA:3.30.70.560 2 172 3.5E-53 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THERU_08465 cdfe501b0479f8a3124cdde998d81551 173 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 131 6.4E-41 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THERU_08465 cdfe501b0479f8a3124cdde998d81551 173 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 131 6.0E-38 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THERU_08465 cdfe501b0479f8a3124cdde998d81551 173 SUPERFAMILY SSF55083 3 150 6.02E-50 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THERU_08465 cdfe501b0479f8a3124cdde998d81551 173 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 86 97 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THERU_00200 0faa63ce7a4a9a476328efd8ad6d1da3 85 Gene3D G3DSA:3.40.30.10 1 85 1.7E-15 T 12-10-2018 THERU_00200 0faa63ce7a4a9a476328efd8ad6d1da3 85 Pfam PF13192 Thioredoxin domain 12 83 1.1E-14 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_00200 0faa63ce7a4a9a476328efd8ad6d1da3 85 SUPERFAMILY SSF52833 4 84 4.39E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_00520 7290ea27301fce1094f222b7914ac162 167 Gene3D G3DSA:3.40.390.10 2 167 9.8E-55 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 THERU_00520 7290ea27301fce1094f222b7914ac162 167 Hamap MF_01842 Archaemetzincin [amzA]. 1 166 32.789 T 12-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 THERU_00520 7290ea27301fce1094f222b7914ac162 167 PIRSF PIRSF005785 1 167 1.3E-53 T 12-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 THERU_00520 7290ea27301fce1094f222b7914ac162 167 SUPERFAMILY SSF55486 30 161 1.7E-14 T 12-10-2018 THERU_00520 7290ea27301fce1094f222b7914ac162 167 Pfam PF07998 Peptidase family M54 41 166 1.2E-29 T 12-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 Gene3D G3DSA:3.40.50.720 187 346 2.3E-181 T 12-10-2018 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 Gene3D G3DSA:3.40.50.1480 5 407 2.3E-181 T 12-10-2018 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 SUPERFAMILY SSF51735 185 347 6.93E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 SMART SM00997 185 346 4.5E-112 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 418 7.2E-210 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 207 223 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 185 345 1.0E-55 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 418 49.213 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 SUPERFAMILY SSF52283 1 418 1.64E-98 T 12-10-2018 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 PIRSF PIRSF001109 1 418 2.8E-191 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 135 8.6E-37 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03705 fea68adf36f4f80ce64d0a29d4ea731f 418 SMART SM00996 2 417 5.6E-150 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 29 185 3.6E-62 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 SUPERFAMILY SSF55021 29 103 1.45E-20 T 12-10-2018 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 28 103 1.0E-30 T 12-10-2018 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 SUPERFAMILY SSF55021 103 185 2.9E-27 T 12-10-2018 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 Pfam PF10369 Small subunit of acetolactate synthase 111 184 2.1E-30 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 Gene3D G3DSA:3.30.70.260 26 105 3.0E-29 T 12-10-2018 THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 Pfam PF01842 ACT domain 30 95 1.8E-14 T 12-10-2018 IPR002912 ACT domain THERU_03265 501b4da61141f3c0829bc0924c34fa16 187 Gene3D G3DSA:3.30.70.1150 110 187 1.2E-32 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal THERU_02025 8a950e227e828fcf11ad520a6d0adc58 351 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 278 350 1.8E-20 T 12-10-2018 IPR006260 TonB/TolA, C-terminal THERU_02025 8a950e227e828fcf11ad520a6d0adc58 351 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 276 350 1.3E-22 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 THERU_02025 8a950e227e828fcf11ad520a6d0adc58 351 SUPERFAMILY SSF74653 272 348 3.92E-18 T 12-10-2018 THERU_02025 8a950e227e828fcf11ad520a6d0adc58 351 Gene3D G3DSA:3.30.1150.10 263 351 5.9E-20 T 12-10-2018 THERU_04030 a4c9f05e8f848b66475f51214aac7f8e 326 SUPERFAMILY SSF53448 8 203 1.95E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_04030 a4c9f05e8f848b66475f51214aac7f8e 326 Gene3D G3DSA:3.90.550.10 1 246 1.0E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_04030 a4c9f05e8f848b66475f51214aac7f8e 326 Pfam PF00535 Glycosyl transferase family 2 11 135 3.6E-26 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Gene3D G3DSA:3.30.1490.20 21 103 8.1E-92 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Pfam PF08442 ATP-grasp domain 2 198 1.0E-77 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Gene3D G3DSA:3.40.50.261 236 382 4.7E-57 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 382 8.7E-177 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 SUPERFAMILY SSF52210 235 381 3.92E-55 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 PIRSF PIRSF001554 1 382 1.8E-154 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Pfam PF00549 CoA-ligase 258 377 3.1E-22 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 382 43.497 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 Gene3D G3DSA:3.30.470.20 1 230 8.1E-92 T 12-10-2018 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 SUPERFAMILY SSF56059 1 233 2.12E-77 T 12-10-2018 THERU_02575 570fbe67e3ac139c5766ce314ff515b8 382 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 253 278 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 Gene3D G3DSA:3.20.20.70 7 364 2.2E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 SMART SM00729 65 290 7.1E-7 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 18 365 5.7E-148 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 PIRSF PIRSF004762 2 369 2.7E-119 T 12-10-2018 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 Pfam PF04055 Radical SAM superfamily 69 240 7.5E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 62 364 3.6E-118 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 SUPERFAMILY SSF102114 25 357 2.88E-51 T 12-10-2018 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 16 368 51.425 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 THERU_02910 5e94debbb9b358e3998f0c844b2e4096 369 Pfam PF13394 4Fe-4S single cluster domain 72 172 1.4E-6 T 12-10-2018 THERU_02995 3b1474684031033595f6594fa2dcd090 378 SUPERFAMILY SSF56266 8 375 5.75E-115 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THERU_02995 3b1474684031033595f6594fa2dcd090 378 Gene3D G3DSA:3.10.20.340 251 378 4.4E-42 T 12-10-2018 THERU_02995 3b1474684031033595f6594fa2dcd090 378 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 6 378 7.6E-110 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THERU_02995 3b1474684031033595f6594fa2dcd090 378 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 11 378 2.0E-142 T 12-10-2018 THERU_02995 3b1474684031033595f6594fa2dcd090 378 Gene3D G3DSA:3.60.70.12 3 250 5.0E-78 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THERU_02995 3b1474684031033595f6594fa2dcd090 378 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 378 107.655 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THERU_02995 3b1474684031033595f6594fa2dcd090 378 Pfam PF01960 ArgJ family 9 378 6.3E-125 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THERU_07505 c17ae7e0fa7b116d4bf7ab3789a6bf57 312 SUPERFAMILY SSF52540 12 200 8.68E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07505 c17ae7e0fa7b116d4bf7ab3789a6bf57 312 Pfam PF13177 DNA polymerase III, delta subunit 82 178 3.7E-31 T 12-10-2018 THERU_07505 c17ae7e0fa7b116d4bf7ab3789a6bf57 312 Pfam PF13177 DNA polymerase III, delta subunit 5 62 4.5E-12 T 12-10-2018 THERU_07505 c17ae7e0fa7b116d4bf7ab3789a6bf57 312 Gene3D G3DSA:3.40.50.300 1 177 4.9E-52 T 12-10-2018 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 159 172 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Gene3D G3DSA:1.10.8.60 304 375 1.0E-21 T 12-10-2018 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 219 234 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Gene3D G3DSA:3.40.50.300 126 303 6.2E-65 T 12-10-2018 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 SMART SM00448 8 119 4.4E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Pfam PF00158 Sigma-54 interaction domain 135 299 3.5E-62 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 SUPERFAMILY SSF52540 134 371 1.06E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 SUPERFAMILY SSF52172 7 180 6.12E-41 T 12-10-2018 IPR011006 CheY-like superfamily THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Pfam PF02954 Bacterial regulatory protein, Fis family 397 432 4.0E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Gene3D G3DSA:1.10.10.60 379 438 1.2E-18 T 12-10-2018 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Pfam PF00072 Response regulator receiver domain 11 118 2.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 SMART SM00382 155 296 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 SUPERFAMILY SSF46689 341 436 3.36E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_01815 a8065bcdf0bf0e8e081c75167ae996ac 438 Gene3D G3DSA:3.40.50.2300 8 125 4.2E-36 T 12-10-2018 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SUPERFAMILY SSF47384 210 291 2.94E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SMART SM00387 335 437 3.3E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_05580 799463bf7924dd95058cda9a9eece01d 437 Gene3D G3DSA:1.20.1480.50 136 227 2.3E-10 T 12-10-2018 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SUPERFAMILY SSF158472 173 224 4.71E-6 T 12-10-2018 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 Gene3D G3DSA:3.30.565.10 295 436 5.3E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SMART SM00304 171 225 5.3E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SMART SM00388 226 292 2.8E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 394 2.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 2.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 2.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 2.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 SUPERFAMILY SSF55874 287 431 4.32E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_05580 799463bf7924dd95058cda9a9eece01d 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 432 5.9E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_05580 799463bf7924dd95058cda9a9eece01d 437 Gene3D G3DSA:1.10.287.130 228 292 5.4E-11 T 12-10-2018 THERU_05580 799463bf7924dd95058cda9a9eece01d 437 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 291 6.4E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_00750 fda3b35c29e008c0e618d93f5a0f92e2 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 4 63 8.5E-31 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_00750 fda3b35c29e008c0e618d93f5a0f92e2 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 63 27.968 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_00750 fda3b35c29e008c0e618d93f5a0f92e2 80 Gene3D G3DSA:2.30.30.100 1 72 3.2E-30 T 12-10-2018 THERU_00750 fda3b35c29e008c0e618d93f5a0f92e2 80 SUPERFAMILY SSF50182 5 63 7.16E-22 T 12-10-2018 IPR010920 LSM domain superfamily THERU_00750 fda3b35c29e008c0e618d93f5a0f92e2 80 Pfam PF17209 Hfq protein 5 67 8.6E-30 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 Gene3D G3DSA:1.10.1060.10 104 224 7.6E-26 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 SUPERFAMILY SSF54292 4 102 1.31E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 Gene3D G3DSA:3.10.20.30 1 102 1.8E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_04095 1c9f30757283b0677ff5037929365fa6 225 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 216 1.6E-58 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 Pfam PF13183 4Fe-4S dicluster domain 139 208 4.9E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_04095 1c9f30757283b0677ff5037929365fa6 225 SUPERFAMILY SSF46548 127 217 5.76E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_04095 1c9f30757283b0677ff5037929365fa6 225 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_04095 1c9f30757283b0677ff5037929365fa6 225 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 1.3E-31 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 421 6.6E-139 T 12-10-2018 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 Gene3D G3DSA:2.30.40.10 361 423 7.4E-9 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 SUPERFAMILY SSF51338 2 422 5.41E-29 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 Pfam PF01979 Amidohydrolase family 52 418 1.1E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 ProSitePatterns PS00482 Dihydroorotase signature 1. 59 67 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 Hamap MF_00220_B Dihydroorotase [pyrC]. 4 421 42.98 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 SUPERFAMILY SSF51556 57 364 4.9E-98 T 12-10-2018 IPR032466 Metal-dependent hydrolase THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 Gene3D G3DSA:2.30.40.10 2 61 2.0E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THERU_06115 ff815c5a8547dd26ae1393c94bf8d01e 423 Gene3D G3DSA:3.20.20.140 62 360 6.1E-118 T 12-10-2018 THERU_04450 70e489a0e65e4593979f8effed424cee 717 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 379 435 1.3E-10 T 12-10-2018 IPR019121 CRISPR-associated protein, CXXC-CXXC domain THERU_04450 70e489a0e65e4593979f8effed424cee 717 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 378 664 9.1E-37 T 12-10-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC THERU_04450 70e489a0e65e4593979f8effed424cee 717 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 45 5.8E-9 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal THERU_04450 70e489a0e65e4593979f8effed424cee 717 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 3 142 6.7E-12 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 THERU_04450 70e489a0e65e4593979f8effed424cee 717 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 204 2.1E-50 T 12-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type THERU_01525 eb63688f522968b469403025177d7e37 129 Pfam PF00411 Ribosomal protein S11 18 128 6.0E-46 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THERU_01525 eb63688f522968b469403025177d7e37 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 9 126 7.1E-54 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01525 eb63688f522968b469403025177d7e37 129 PIRSF PIRSF002131 1 129 4.3E-51 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THERU_01525 eb63688f522968b469403025177d7e37 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site THERU_01525 eb63688f522968b469403025177d7e37 129 SUPERFAMILY SSF53137 15 129 9.16E-44 T 12-10-2018 THERU_01525 eb63688f522968b469403025177d7e37 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.805 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THERU_01525 eb63688f522968b469403025177d7e37 129 Gene3D G3DSA:3.30.420.80 1 129 1.6E-49 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 70 1.0E-9 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 Gene3D G3DSA:3.30.1280.10 1 70 2.1E-21 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 70 7.8E-17 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 70 16.003 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 SUPERFAMILY SSF82697 1 70 2.62E-21 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_01830 e2f50451bb36dd0e0a4a6bb90426f9db 70 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 70 3.5E-21 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_04935 3f4eef40a1554eae291c46c059920873 252 PRINTS PR00446 Hydrogen uptake protein signature 4 16 8.2E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 PRINTS PR00446 Hydrogen uptake protein signature 67 83 8.2E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 PRINTS PR00446 Hydrogen uptake protein signature 16 27 8.2E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 PRINTS PR00446 Hydrogen uptake protein signature 56 66 8.2E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 PRINTS PR00446 Hydrogen uptake protein signature 35 52 8.2E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 150 5.7E-43 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04935 3f4eef40a1554eae291c46c059920873 252 SUPERFAMILY SSF53163 3 152 3.14E-40 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily THERU_04935 3f4eef40a1554eae291c46c059920873 252 Gene3D G3DSA:3.40.50.1450 2 155 1.7E-44 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily THERU_04935 3f4eef40a1554eae291c46c059920873 252 Pfam PF01750 Hydrogenase maturation protease 22 149 2.1E-20 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_07205 d6c7a998a75238636ca7b0d944819501 357 Gene3D G3DSA:3.40.50.11720 1 159 3.5E-43 T 12-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 THERU_07205 d6c7a998a75238636ca7b0d944819501 357 Gene3D G3DSA:3.40.50.2000 165 354 2.6E-42 T 12-10-2018 THERU_07205 d6c7a998a75238636ca7b0d944819501 357 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 5 158 9.3E-27 T 12-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 THERU_07205 d6c7a998a75238636ca7b0d944819501 357 SUPERFAMILY SSF53756 20 307 1.51E-6 T 12-10-2018 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 Pfam PF04545 Sigma-70, region 4 177 226 3.4E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 12 229 3.4E-62 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 Pfam PF04539 Sigma-70 region 3 92 164 2.5E-6 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 Pfam PF04542 Sigma-70 region 2 13 79 5.2E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 SUPERFAMILY SSF88659 84 148 4.36E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 SUPERFAMILY SSF88659 146 230 1.16E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 SUPERFAMILY SSF88946 10 80 1.06E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 Gene3D G3DSA:1.20.140.160 80 231 4.2E-40 T 12-10-2018 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 PRINTS PR00046 Major sigma-70 factor signature 38 51 5.5E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 PRINTS PR00046 Major sigma-70 factor signature 213 224 5.5E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 PRINTS PR00046 Major sigma-70 factor signature 181 193 5.5E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 PRINTS PR00046 Major sigma-70 factor signature 198 213 5.5E-7 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 Gene3D G3DSA:1.10.1740.10 1 79 1.6E-21 T 12-10-2018 THERU_06290 52e5ce834989b291cdf772ec0800b01f 232 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 228 9.5E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Gene3D G3DSA:1.10.1780.10 1 143 6.9E-42 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SUPERFAMILY SSF81923 3 140 7.85E-25 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SUPERFAMILY SSF52540 154 463 2.9E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Gene3D G3DSA:4.10.860.10 407 459 2.5E-18 T 12-10-2018 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Gene3D G3DSA:1.10.8.60 707 809 1.5E-23 T 12-10-2018 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 707 787 2.7E-21 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SMART SM01086 707 796 6.6E-27 T 12-10-2018 IPR019489 Clp ATPase, C-terminal THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SUPERFAMILY SSF52540 479 792 1.75E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 564 582 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF07724 AAA domain (Cdc48 subfamily) 529 701 3.4E-54 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 88 140 4.7E-15 T 12-10-2018 IPR004176 Clp, N-terminal THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 63 3.1E-12 T 12-10-2018 IPR004176 Clp, N-terminal THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 288 300 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Gene3D G3DSA:3.40.50.300 145 335 1.1E-75 T 12-10-2018 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 626 2.4E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 534 552 2.4E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 579 597 2.4E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 641 655 2.4E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Gene3D G3DSA:3.40.50.300 483 705 7.8E-90 T 12-10-2018 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SMART SM00382 530 674 1.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 SMART SM00382 193 337 1.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF02151 UvrB/uvrC motif 410 444 6.4E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 THERU_08360 990e2cffdbe9e1af8308b6eabd5ab3b5 814 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 312 9.6E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_00230 26005dc191db92532811878936687ec8 245 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 42 213 5.4E-42 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG THERU_00230 26005dc191db92532811878936687ec8 245 Pfam PF03641 Possible lysine decarboxylase 84 213 2.3E-33 T 12-10-2018 IPR031100 LOG family THERU_00230 26005dc191db92532811878936687ec8 245 SUPERFAMILY SSF102405 17 214 5.8E-59 T 12-10-2018 THERU_00230 26005dc191db92532811878936687ec8 245 Gene3D G3DSA:3.40.50.450 19 219 1.5E-62 T 12-10-2018 THERU_06650 dde3e0046cc35e947c14d25546fdbf40 129 Pfam PF13682 Chemoreceptor zinc-binding domain 20 86 2.5E-7 T 12-10-2018 IPR025991 Chemoreceptor zinc-binding domain THERU_03245 7426426ac890baa8ac44ba6433397ab4 95 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THERU_03245 7426426ac890baa8ac44ba6433397ab4 95 Gene3D G3DSA:3.10.20.30 1 95 3.3E-13 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_03245 7426426ac890baa8ac44ba6433397ab4 95 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 83 1.4E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THERU_03245 7426426ac890baa8ac44ba6433397ab4 95 SUPERFAMILY SSF54292 7 86 1.48E-15 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 Gene3D G3DSA:3.40.50.300 260 370 4.6E-14 T 12-10-2018 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 Gene3D G3DSA:3.40.50.300 441 621 8.6E-32 T 12-10-2018 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 SMART SM00155 76 103 9.3E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 Pfam PF13091 PLD-like domain 8 126 6.6E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 SUPERFAMILY SSF52540 289 612 2.47E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 SMART SM00382 301 580 0.0053 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 SUPERFAMILY SSF56024 5 139 1.23E-15 T 12-10-2018 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 Gene3D G3DSA:3.30.870.10 1 147 3.7E-18 T 12-10-2018 THERU_06415 96e0a6fb96938ad50b13d2706c0dd015 621 Pfam PF01935 Domain of unknown function DUF87 284 490 1.4E-20 T 12-10-2018 IPR002789 Helicase HerA, central domain THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 SUPERFAMILY SSF51344 2 80 1.14E-19 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 2 79 5.8E-23 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 Gene3D G3DSA:2.60.15.10 1 128 1.3E-27 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 7 80 1.0E-27 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 126 16.309 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_01685 d3b07c2d4db7b4a300fdff98e551a296 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 1 128 2.5E-37 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05060 cd5b81b5b7dbfbcb5ca0b30391e85214 255 Gene3D G3DSA:3.30.70.1900 132 248 1.6E-31 T 12-10-2018 THERU_05060 cd5b81b5b7dbfbcb5ca0b30391e85214 255 Gene3D G3DSA:3.30.70.1890 5 130 2.5E-14 T 12-10-2018 THERU_05060 cd5b81b5b7dbfbcb5ca0b30391e85214 255 PIRSF PIRSF005054 9 252 9.7E-65 T 12-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 THERU_05060 cd5b81b5b7dbfbcb5ca0b30391e85214 255 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 54 246 1.3E-37 T 12-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 THERU_05060 cd5b81b5b7dbfbcb5ca0b30391e85214 255 Pfam PF01881 CRISPR associated protein Cas6 104 246 1.3E-36 T 12-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 SUPERFAMILY SSF46977 398 494 2.22E-24 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 Pfam PF02910 Fumarate reductase flavoprotein C-term 408 496 1.6E-14 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 327 349 7.8E-7 T 12-10-2018 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 7.8E-7 T 12-10-2018 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 Pfam PF00890 FAD binding domain 18 364 1.5E-72 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 Gene3D G3DSA:3.50.50.60 20 371 7.7E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 SUPERFAMILY SSF51905 6 380 8.92E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 SUPERFAMILY SSF56425 219 324 1.79E-31 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 9.5E-7 T 12-10-2018 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 9.5E-7 T 12-10-2018 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 349 9.5E-7 T 12-10-2018 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 Gene3D G3DSA:3.90.700.10 227 319 7.7E-115 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01665 de71d7e811f83ea88cffe34499f17f73 503 Gene3D G3DSA:1.20.58.100 382 483 1.0E-19 T 12-10-2018 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Gene3D G3DSA:3.40.50.12160 8 132 5.0E-39 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Gene3D G3DSA:2.40.50.140 363 428 5.8E-12 T 12-10-2018 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 134 154 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 SUPERFAMILY SSF102114 99 353 3.66E-54 T 12-10-2018 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Pfam PF00919 Uncharacterized protein family UPF0004 9 102 2.4E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Pfam PF04055 Radical SAM superfamily 136 306 3.0E-22 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 8 426 61.598 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 9 422 2.3E-158 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 SMART SM00729 130 348 5.6E-46 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 422 2.5E-122 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THERU_05325 c035c69e0f5a40fa2b906bb8d7903661 429 Gene3D G3DSA:3.80.30.20 133 361 1.2E-77 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_06125 b41f2cfaa0291575a43ac1be62935e94 173 SUPERFAMILY SSF51161 6 169 9.15E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily THERU_06125 b41f2cfaa0291575a43ac1be62935e94 173 Gene3D G3DSA:2.160.10.10 2 173 4.5E-62 T 12-10-2018 THERU_06125 b41f2cfaa0291575a43ac1be62935e94 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 90 124 1.2E-8 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_06125 b41f2cfaa0291575a43ac1be62935e94 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 46 2.3E-4 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 Pfam PF00425 chorismate binding enzyme 91 331 5.7E-74 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 SUPERFAMILY SSF56322 74 337 6.02E-87 T 12-10-2018 IPR005801 ADC synthase GO:0009058 THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 Gene3D G3DSA:3.60.120.10 23 338 2.1E-93 T 12-10-2018 IPR005801 ADC synthase GO:0009058 THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 PRINTS PR00095 Anthranilate synthase component I signature 182 195 8.4E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 PRINTS PR00095 Anthranilate synthase component I signature 288 302 8.4E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 PRINTS PR00095 Anthranilate synthase component I signature 196 209 8.4E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_08310 efa2190083df9f8c1b83e01a39289fd5 338 PRINTS PR00095 Anthranilate synthase component I signature 274 288 8.4E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 SUPERFAMILY SSF74942 87 154 1.1E-12 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 Gene3D G3DSA:2.30.30.180 91 154 7.8E-6 T 12-10-2018 THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 Pfam PF02576 RimP N-terminal domain 16 85 1.2E-25 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 Gene3D G3DSA:3.30.300.70 4 83 2.8E-27 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 10 156 24.382 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 Pfam PF17384 RimP C-terminal SH3 domain 89 155 1.1E-16 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal THERU_07695 cff47a82fbe7757cd2fa9bc659f98a88 157 SUPERFAMILY SSF75420 8 85 5.49E-23 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 263 41.945 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 Gene3D G3DSA:3.20.20.60 1 264 1.8E-111 T 12-10-2018 THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 SUPERFAMILY SSF51621 2 261 4.93E-101 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 2 259 5.6E-108 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 2.6E-98 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THERU_04495 e951b5af42808130bc4b8aa601498dbf 264 PIRSF PIRSF000388 1 264 1.1E-110 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THERU_04445 e7629919bf271a1c2a9925eb59e40fee 351 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 12 342 5.0E-49 T 12-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap THERU_04445 e7629919bf271a1c2a9925eb59e40fee 351 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 272 8.2E-67 T 12-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR THERU_04445 e7629919bf271a1c2a9925eb59e40fee 351 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 13 266 3.3E-35 T 12-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 132 152 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 SUPERFAMILY SSF51905 2 301 2.12E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 192 208 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 230 251 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 301 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 2.2E-67 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 301 1.9E-118 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 Gene3D G3DSA:3.50.50.60 119 241 5.9E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.0E-34 T 12-10-2018 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 3.0E-34 T 12-10-2018 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.0E-34 T 12-10-2018 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-34 T 12-10-2018 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 3.0E-34 T 12-10-2018 THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 Gene3D G3DSA:3.50.50.60 5 300 5.9E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00330 154eb6a24d023c7409a1f148e01f2ec7 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 290 6.0E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_08285 cbbe179b09c1ff1eff375e6dad7636da 440 Gene3D G3DSA:3.30.2290.10 2 215 3.7E-40 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal THERU_08285 cbbe179b09c1ff1eff375e6dad7636da 440 SUPERFAMILY SSF111283 7 440 4.19E-101 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 THERU_08285 cbbe179b09c1ff1eff375e6dad7636da 440 Pfam PF01523 Putative modulator of DNA gyrase 17 307 1.3E-50 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 645 688 4.1E-20 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Gene3D G3DSA:3.30.54.20 616 669 1.5E-51 T 12-10-2018 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Pfam PF01411 tRNA synthetases class II (A) 5 548 7.0E-222 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Pfam PF02272 DHHA1 domain 725 860 8.6E-24 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 SUPERFAMILY SSF50447 446 544 2.01E-18 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Gene3D G3DSA:3.30.930.10 1 231 1.5E-115 T 12-10-2018 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 SUPERFAMILY SSF101353 235 453 3.4E-67 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 2.8E-33 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 PRINTS PR00980 Alanyl-tRNA synthetase signature 215 228 2.8E-33 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 PRINTS PR00980 Alanyl-tRNA synthetase signature 289 302 2.8E-33 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 PRINTS PR00980 Alanyl-tRNA synthetase signature 265 281 2.8E-33 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 PRINTS PR00980 Alanyl-tRNA synthetase signature 188 199 2.8E-33 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Gene3D G3DSA:3.30.980.10 548 687 1.5E-51 T 12-10-2018 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Gene3D G3DSA:2.40.30.130 469 544 1.6E-9 T 12-10-2018 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 SUPERFAMILY SSF55681 2 234 1.62E-108 T 12-10-2018 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 845 1.8E-301 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 SUPERFAMILY SSF55186 544 702 6.41E-51 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 SMART SM00863 645 688 3.8E-22 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 863 178.659 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 THERU_07665 90e7e02cb7e77415b021d4a2e4bb23b7 863 Gene3D G3DSA:3.10.310.40 754 863 1.1E-29 T 12-10-2018 THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 Pfam PF01266 FAD dependent oxidoreductase 2 323 5.3E-46 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 SUPERFAMILY SSF54373 205 289 2.22E-13 T 12-10-2018 THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 SUPERFAMILY SSF51905 1 343 1.42E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 3 329 8.4E-78 T 12-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 Gene3D G3DSA:3.50.50.60 3 326 6.6E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01070 fb5e05ffb0a536eb1c610c960139d914 343 Gene3D G3DSA:3.30.9.10 86 288 6.6E-57 T 12-10-2018 THERU_02400 a97a4d802848071d2b2c4217497d89a3 249 Pfam PF01734 Patatin-like phospholipase 5 161 8.9E-22 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THERU_02400 a97a4d802848071d2b2c4217497d89a3 249 SUPERFAMILY SSF52151 1 244 3.66E-51 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THERU_02400 a97a4d802848071d2b2c4217497d89a3 249 Gene3D G3DSA:3.40.1090.10 1 94 5.4E-26 T 12-10-2018 THERU_07580 951838b208f54ba50988936382874179 413 SUPERFAMILY SSF53244 286 410 1.08E-20 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_07580 951838b208f54ba50988936382874179 413 Pfam PF02875 Mur ligase family, glutamate ligase domain 284 358 3.0E-6 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THERU_07580 951838b208f54ba50988936382874179 413 PIRSF PIRSF001563 1 413 1.1E-94 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THERU_07580 951838b208f54ba50988936382874179 413 SUPERFAMILY SSF53623 8 284 6.87E-69 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_07580 951838b208f54ba50988936382874179 413 Gene3D G3DSA:3.90.190.20 286 413 1.8E-23 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_07580 951838b208f54ba50988936382874179 413 Gene3D G3DSA:3.40.1190.10 2 285 1.5E-72 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_07580 951838b208f54ba50988936382874179 413 Pfam PF08245 Mur ligase middle domain 45 263 2.6E-10 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THERU_07580 951838b208f54ba50988936382874179 413 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 407 4.1E-96 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 3 566 5.2E-212 T 12-10-2018 IPR030998 Thiosulfohydrolase SoxB THERU_04700 e1bcf4893d551efac69425f586a1f090 576 Gene3D G3DSA:3.60.21.10 103 374 4.5E-79 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like THERU_04700 e1bcf4893d551efac69425f586a1f090 576 Pfam PF02872 5'-nucleotidase, C-terminal domain 392 524 1.2E-9 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 Gene3D G3DSA:3.90.780.10 375 573 1.2E-60 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 SUPERFAMILY SSF55816 372 566 5.89E-24 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 SUPERFAMILY SSF56300 37 373 6.77E-72 T 12-10-2018 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 PRINTS PR01607 Apyrase family signature 284 307 9.9E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 PRINTS PR01607 Apyrase family signature 39 57 9.9E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 PRINTS PR01607 Apyrase family signature 312 332 9.9E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 PRINTS PR01607 Apyrase family signature 265 282 9.9E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_04700 e1bcf4893d551efac69425f586a1f090 576 PRINTS PR01607 Apyrase family signature 513 532 9.9E-14 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THERU_07195 65f152f6c0fa872c95a7a13175c58ce0 314 Gene3D G3DSA:3.40.50.2000 1 137 6.1E-22 T 12-10-2018 THERU_07195 65f152f6c0fa872c95a7a13175c58ce0 314 Gene3D G3DSA:3.40.50.2000 145 314 1.1E-33 T 12-10-2018 THERU_07195 65f152f6c0fa872c95a7a13175c58ce0 314 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 62 262 2.4E-36 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THERU_07195 65f152f6c0fa872c95a7a13175c58ce0 314 SUPERFAMILY SSF53756 1 312 3.14E-72 T 12-10-2018 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 SMART SM00028 373 406 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 SMART SM00028 271 304 24.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 SMART SM00028 339 372 0.71 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 Gene3D G3DSA:3.30.2010.10 57 139 3.5E-8 T 12-10-2018 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 SUPERFAMILY SSF48452 275 403 1.85E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 Pfam PF01435 Peptidase family M48 63 237 6.7E-36 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 Gene3D G3DSA:1.25.40.10 257 404 6.9E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_08370 6b059afc0bfb452beca31bf8d4f094dc 420 Pfam PF13176 Tetratricopeptide repeat 376 402 0.031 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 Pfam PF02237 Biotin protein ligase C terminal domain 184 229 2.3E-8 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 9 229 1.5E-46 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 Gene3D G3DSA:3.30.930.10 4 181 3.5E-52 T 12-10-2018 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 Pfam PF03099 Biotin/lipoate A/B protein ligase family 25 125 6.2E-14 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 SUPERFAMILY SSF50037 188 229 3.25E-6 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 Gene3D G3DSA:2.30.30.100 185 230 2.5E-11 T 12-10-2018 THERU_03825 db8939dee5fb36ea7cb6503a2de16a26 234 SUPERFAMILY SSF55681 3 182 1.55E-46 T 12-10-2018 THERU_04705 9467d8a9adc8e06d9a947b7ee64b56fb 192 SUPERFAMILY SSF46626 66 184 1.92E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_04705 9467d8a9adc8e06d9a947b7ee64b56fb 192 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 97 185 2.7E-25 T 12-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX THERU_04705 9467d8a9adc8e06d9a947b7ee64b56fb 192 Gene3D G3DSA:1.10.760.10 1 192 2.2E-59 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_04705 9467d8a9adc8e06d9a947b7ee64b56fb 192 Pfam PF00034 Cytochrome c 100 184 3.6E-4 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02535 2afddc6ada711c830e07825561289726 311 Gene3D G3DSA:3.40.1190.20 7 306 1.8E-99 T 12-10-2018 IPR029056 Ribokinase-like THERU_02535 2afddc6ada711c830e07825561289726 311 SUPERFAMILY SSF53613 15 307 3.27E-53 T 12-10-2018 IPR029056 Ribokinase-like THERU_02535 2afddc6ada711c830e07825561289726 311 Pfam PF00294 pfkB family carbohydrate kinase 17 298 6.2E-44 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB THERU_02535 2afddc6ada711c830e07825561289726 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 56 79 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 SUPERFAMILY SSF52016 373 552 2.9E-62 T 12-10-2018 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 Pfam PF00920 Dehydratase family 31 550 3.0E-229 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 SUPERFAMILY SSF143975 1 372 5.75E-145 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 3.7E-253 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 461 472 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 553 48.721 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THERU_01875 7ed3842d806b912690ec6dbf3dee38be 554 Gene3D G3DSA:3.50.30.80 373 524 7.2E-56 T 12-10-2018 THERU_02530 864b2f61fa6825cc25a0acddd25e4ea0 201 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 17 191 25.51 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02530 864b2f61fa6825cc25a0acddd25e4ea0 201 Pfam PF13237 4Fe-4S dicluster domain 84 138 2.6E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_02530 864b2f61fa6825cc25a0acddd25e4ea0 201 Gene3D G3DSA:3.30.70.3270 43 192 1.9E-24 T 12-10-2018 THERU_02530 864b2f61fa6825cc25a0acddd25e4ea0 201 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 127 138 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02530 864b2f61fa6825cc25a0acddd25e4ea0 201 SUPERFAMILY SSF46548 24 159 4.97E-20 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_02125 7021212158b1567ffe0320018b946b5b 305 SUPERFAMILY SSF55060 161 272 3.17E-31 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THERU_02125 7021212158b1567ffe0320018b946b5b 305 Gene3D G3DSA:3.30.70.890 157 287 5.4E-44 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THERU_02125 7021212158b1567ffe0320018b946b5b 305 Hamap MF_00384 Homoserine kinase [thrB]. 8 298 29.177 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 THERU_02125 7021212158b1567ffe0320018b946b5b 305 Gene3D G3DSA:3.30.230.10 6 156 1.5E-38 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_02125 7021212158b1567ffe0320018b946b5b 305 Pfam PF08544 GHMP kinases C terminal 203 272 3.3E-10 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain THERU_02125 7021212158b1567ffe0320018b946b5b 305 PRINTS PR00958 Homoserine kinase signature 128 141 1.1E-30 T 12-10-2018 THERU_02125 7021212158b1567ffe0320018b946b5b 305 PRINTS PR00958 Homoserine kinase signature 245 260 1.1E-30 T 12-10-2018 THERU_02125 7021212158b1567ffe0320018b946b5b 305 PRINTS PR00958 Homoserine kinase signature 94 109 1.1E-30 T 12-10-2018 THERU_02125 7021212158b1567ffe0320018b946b5b 305 PRINTS PR00958 Homoserine kinase signature 166 183 1.1E-30 T 12-10-2018 THERU_02125 7021212158b1567ffe0320018b946b5b 305 PRINTS PR00958 Homoserine kinase signature 13 28 1.1E-30 T 12-10-2018 THERU_02125 7021212158b1567ffe0320018b946b5b 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 87 98 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 THERU_02125 7021212158b1567ffe0320018b946b5b 305 TIGRFAM TIGR00191 thrB: homoserine kinase 8 296 1.2E-77 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 THERU_02125 7021212158b1567ffe0320018b946b5b 305 PIRSF PIRSF000676 4 300 1.5E-88 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 THERU_02125 7021212158b1567ffe0320018b946b5b 305 SUPERFAMILY SSF54211 6 146 2.43E-28 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_02125 7021212158b1567ffe0320018b946b5b 305 Pfam PF00288 GHMP kinases N terminal domain 81 141 4.6E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 THERU_02490 84a81dcf17876df0c4299d12acddfecf 349 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 53 68 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02490 84a81dcf17876df0c4299d12acddfecf 349 Pfam PF00146 NADH dehydrogenase 13 341 1.4E-114 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02490 84a81dcf17876df0c4299d12acddfecf 349 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 347 23.396 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PIRSF PIRSF000724 2 398 3.6E-149 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 Gene3D G3DSA:3.40.50.1260 12 394 4.7E-159 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 Pfam PF00162 Phosphoglycerate kinase 12 386 1.3E-155 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 17 27 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 Gene3D G3DSA:3.40.50.1260 173 386 4.7E-159 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 194 213 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 372 389 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 12 28 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 PRINTS PR00477 Phosphoglycerate kinase family signature 171 193 1.6E-88 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 396 40.801 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_07030 49b562331de02ace36ba2bb99dc2a24f 398 SUPERFAMILY SSF53748 4 396 7.42E-153 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 330 1.5E-85 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Pfam PF01706 FliG C-terminal domain 221 327 3.3E-41 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Gene3D G3DSA:1.10.220.30 1 89 1.6E-17 T 12-10-2018 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Gene3D G3DSA:1.10.220.30 198 332 5.2E-45 T 12-10-2018 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 SUPERFAMILY SSF48029 10 102 3.4E-14 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PIRSF PIRSF003161 2 334 1.7E-108 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Gene3D G3DSA:1.10.220.30 90 194 2.0E-30 T 12-10-2018 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 116 139 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 4.4E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Pfam PF14842 FliG N-terminal domain 7 103 9.7E-17 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 SUPERFAMILY SSF48029 117 328 4.32E-65 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical THERU_06495 b032cd37794a1cb9c9788b04068fc1b5 334 Pfam PF14841 FliG middle domain 118 189 8.7E-26 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 TIGRFAM TIGR03540 DapC_direct: LL-diaminopimelate aminotransferase 4 383 5.6E-201 T 12-10-2018 IPR019881 Diaminopimelate aminotransferase, DapL, Desulfovibrio-type GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 Gene3D G3DSA:3.90.1150.10 18 382 4.7E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 Pfam PF00155 Aminotransferase class I and II 32 382 1.2E-70 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 Hamap MF_01642 LL-diaminopimelate aminotransferase [dapL]. 2 385 48.448 T 12-10-2018 IPR019942 LL-diaminopimelate aminotransferase/aminotransferase ALD1 GO:0008483 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 SUPERFAMILY SSF53383 1 384 7.75E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02265 a3cb6ad1c0c46c38ccd13fecdbd889eb 387 Gene3D G3DSA:3.40.640.10 43 284 4.7E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_00950 5bf51f698441ff76ea45360862e0a678 202 Gene3D G3DSA:3.40.50.300 1 199 1.2E-60 T 12-10-2018 THERU_00950 5bf51f698441ff76ea45360862e0a678 202 Hamap MF_00165 Thymidylate kinase [tmk]. 4 199 27.387 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THERU_00950 5bf51f698441ff76ea45360862e0a678 202 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 191 6.9E-50 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THERU_00950 5bf51f698441ff76ea45360862e0a678 202 SUPERFAMILY SSF52540 2 200 6.12E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00950 5bf51f698441ff76ea45360862e0a678 202 Pfam PF02223 Thymidylate kinase 8 191 1.2E-49 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 THERU_00950 5bf51f698441ff76ea45360862e0a678 202 ProSitePatterns PS01331 Thymidylate kinase signature. 90 102 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 21 76 8.3E-9 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 98 158 1.3E-6 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 343 422 2.9E-14 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 172 261 2.2E-14 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 262 342 5.6E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 96 162 1.64E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 101 117 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 203 224 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 281 300 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 PRINTS PR00681 Ribosomal protein S1 signature 119 136 3.7E-15 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 19 80 2.8E-8 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 347 415 3.3E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 179 251 1.7E-15 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 96 160 2.2E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 266 332 9.3E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SMART SM00316 430 494 1.8E-17 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Pfam PF00575 S1 RNA binding domain 428 483 1.2E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Pfam PF00575 S1 RNA binding domain 267 332 2.3E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Pfam PF00575 S1 RNA binding domain 178 250 1.9E-9 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Pfam PF00575 S1 RNA binding domain 19 56 6.3E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Pfam PF00575 S1 RNA binding domain 346 406 1.1E-9 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 328 435 4.7E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 Gene3D G3DSA:2.40.50.140 423 497 5.6E-17 T 12-10-2018 THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 3 86 2.24E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 256 333 1.8E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 415 494 5.37E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02175 d60f1c00cbf55f2d6e47c49f670e3a8a 523 SUPERFAMILY SSF50249 176 275 5.48E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07160 5441561f051c5dde0d8506e955ac757b 217 Gene3D G3DSA:3.40.50.150 13 217 6.5E-43 T 12-10-2018 THERU_07160 5441561f051c5dde0d8506e955ac757b 217 Pfam PF01209 ubiE/COQ5 methyltransferase family 4 211 3.2E-27 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THERU_07160 5441561f051c5dde0d8506e955ac757b 217 SUPERFAMILY SSF53335 1 211 5.02E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 PRINTS PR00050 Cold shock protein signature 41 59 3.4E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 PRINTS PR00050 Cold shock protein signature 5 20 3.4E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 PRINTS PR00050 Cold shock protein signature 26 35 3.4E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 SMART SM00357 4 68 1.7E-31 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 Gene3D G3DSA:2.40.50.140 3 69 2.1E-30 T 12-10-2018 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 PIRSF PIRSF002599 1 69 6.6E-27 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 Pfam PF00313 'Cold-shock' DNA-binding domain 4 67 1.2E-31 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 SUPERFAMILY SSF50249 2 68 3.43E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_02700 2ebf4a980e86c1e52abeff709c377a94 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 12-10-2018 IPR019844 Cold-shock conserved site THERU_02020 d1ec791d0be88e7c68556aac2c65b6f6 126 Gene3D G3DSA:3.30.420.270 55 120 1.5E-9 T 12-10-2018 THERU_02020 d1ec791d0be88e7c68556aac2c65b6f6 126 Pfam PF02472 Biopolymer transport protein ExbD/TolR 4 123 7.3E-26 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THERU_02880 c47c5ddf6af1ae6806bd6791281091c1 232 SMART SM00382 29 215 9.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_02880 c47c5ddf6af1ae6806bd6791281091c1 232 Pfam PF00005 ABC transporter 20 168 2.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_02880 c47c5ddf6af1ae6806bd6791281091c1 232 SUPERFAMILY SSF52540 4 226 6.59E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02880 c47c5ddf6af1ae6806bd6791281091c1 232 Gene3D G3DSA:3.40.50.300 2 222 8.3E-65 T 12-10-2018 THERU_01470 0b717706f98c9a02441e11daecc10069 185 Gene3D G3DSA:3.90.930.12 83 179 3.6E-38 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 SUPERFAMILY SSF56053 83 175 3.31E-35 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 175 35.913 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_01470 0b717706f98c9a02441e11daecc10069 185 PIRSF PIRSF002162 1 176 2.7E-56 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 175 3.1E-72 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_01470 0b717706f98c9a02441e11daecc10069 185 SUPERFAMILY SSF56053 1 82 1.42E-25 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 PRINTS PR00059 Ribosomal protein L6 signature 140 161 8.6E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_01470 0b717706f98c9a02441e11daecc10069 185 PRINTS PR00059 Ribosomal protein L6 signature 71 96 8.6E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_01470 0b717706f98c9a02441e11daecc10069 185 PRINTS PR00059 Ribosomal protein L6 signature 99 115 8.6E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THERU_01470 0b717706f98c9a02441e11daecc10069 185 Gene3D G3DSA:3.90.930.12 1 82 1.4E-31 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 Pfam PF00347 Ribosomal protein L6 11 82 4.2E-16 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 Pfam PF00347 Ribosomal protein L6 90 163 1.1E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01470 0b717706f98c9a02441e11daecc10069 185 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 153 161 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07805 821ab2453c33d5322190fa39879c8350 101 Gene3D G3DSA:2.60.120.10 1 101 9.1E-21 T 12-10-2018 IPR014710 RmlC-like jelly roll fold THERU_07805 821ab2453c33d5322190fa39879c8350 101 Pfam PF07883 Cupin domain 32 95 1.1E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel THERU_07805 821ab2453c33d5322190fa39879c8350 101 SUPERFAMILY SSF51182 17 98 6.32E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily THERU_03120 57bf82ac0b1bf2f1982e952bd02218c4 659 Pfam PF07715 TonB-dependent Receptor Plug Domain 40 126 1.9E-10 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain THERU_03120 57bf82ac0b1bf2f1982e952bd02218c4 659 Gene3D G3DSA:2.40.170.20 140 659 1.4E-83 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THERU_03120 57bf82ac0b1bf2f1982e952bd02218c4 659 Gene3D G3DSA:2.170.130.10 30 139 1.2E-15 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THERU_03120 57bf82ac0b1bf2f1982e952bd02218c4 659 SUPERFAMILY SSF56935 40 659 2.2E-94 T 12-10-2018 THERU_03120 57bf82ac0b1bf2f1982e952bd02218c4 659 Pfam PF00593 TonB dependent receptor 245 658 4.5E-41 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 82 96 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 3 392 54.203 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 PIRSF PIRSF001413 1 396 1.2E-171 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 SUPERFAMILY SSF53686 4 391 2.62E-153 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 Gene3D G3DSA:3.40.50.1100 55 385 5.1E-194 T 12-10-2018 THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 54 379 6.6E-45 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 Gene3D G3DSA:3.40.50.1100 11 207 5.1E-194 T 12-10-2018 THERU_01210 e12ec481aade9dd83a7bcbd7b42797c6 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 8 391 2.8E-199 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05960 e8fc4f076ea26bff0147e38e01e7a1ef 83 SUPERFAMILY SSF64307 5 79 4.58E-24 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_05960 e8fc4f076ea26bff0147e38e01e7a1ef 83 Gene3D G3DSA:3.30.110.40 5 81 9.6E-30 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_05960 e8fc4f076ea26bff0147e38e01e7a1ef 83 Pfam PF01206 Sulfurtransferase TusA 12 79 5.5E-22 T 12-10-2018 IPR001455 TusA-like domain THERU_05760 9d3a161042de6f4a37e0cc190a8d1423 304 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 4.3E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05760 9d3a161042de6f4a37e0cc190a8d1423 304 SUPERFAMILY SSF54523 7 64 5.96E-6 T 12-10-2018 THERU_05760 9d3a161042de6f4a37e0cc190a8d1423 304 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 24 4.8E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05760 9d3a161042de6f4a37e0cc190a8d1423 304 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_06645 fde32e6fb25bda9a0070ecfd1dff78b0 232 SUPERFAMILY SSF54862 1 205 2.93E-64 T 12-10-2018 THERU_06645 fde32e6fb25bda9a0070ecfd1dff78b0 232 Pfam PF13247 4Fe-4S dicluster domain 65 167 3.6E-22 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_06645 fde32e6fb25bda9a0070ecfd1dff78b0 232 Gene3D G3DSA:3.30.70.20 1 33 2.1E-5 T 12-10-2018 THERU_06645 fde32e6fb25bda9a0070ecfd1dff78b0 232 Gene3D G3DSA:3.30.70.20 35 226 2.0E-58 T 12-10-2018 THERU_06645 fde32e6fb25bda9a0070ecfd1dff78b0 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_05565 ed7b9707b6f82cc058f19305d86968d8 188 Pfam PF00025 ADP-ribosylation factor family 9 173 5.1E-11 T 12-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 THERU_05565 ed7b9707b6f82cc058f19305d86968d8 188 SUPERFAMILY SSF52540 8 181 7.22E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05565 ed7b9707b6f82cc058f19305d86968d8 188 Gene3D G3DSA:3.40.50.300 1 185 1.8E-57 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 688 696 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 TIGRFAM TIGR00763 lon: endopeptidase La 19 784 3.1E-293 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Gene3D G3DSA:1.20.58.1480 132 256 3.3E-35 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 738 756 8.7E-52 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 369 388 8.7E-52 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 685 704 8.7E-52 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 715 734 8.7E-52 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 623 8.7E-52 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Hamap MF_01973 Lon protease [lon]. 18 785 69.136 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 583 785 7.9E-89 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 SUPERFAMILY SSF52540 319 569 4.24E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Gene3D G3DSA:3.30.230.10 606 791 1.1E-78 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 SMART SM00382 361 506 2.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 SUPERFAMILY SSF88697 17 212 5.96E-38 T 12-10-2018 IPR015947 PUA-like superfamily THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 17 212 4.6E-38 T 12-10-2018 IPR003111 Lon, substrate-binding domain THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Gene3D G3DSA:2.30.130.40 14 123 5.0E-28 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 SMART SM00464 17 213 3.2E-57 T 12-10-2018 IPR003111 Lon, substrate-binding domain THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 PIRSF PIRSF001174 7 788 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 SUPERFAMILY SSF54211 607 783 2.47E-54 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Gene3D G3DSA:1.10.8.60 504 597 3.4E-26 T 12-10-2018 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 365 503 9.5E-24 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THERU_03615 9092e903a97696b6a18d0914e7d6aa64 791 Gene3D G3DSA:3.40.50.300 324 503 3.1E-65 T 12-10-2018 THERU_02395 c3699e22bf1fb5053b3f5e23ad3c5d07 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 409 2.5E-82 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THERU_02395 c3699e22bf1fb5053b3f5e23ad3c5d07 455 PIRSF PIRSF006603 9 450 8.0E-84 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THERU_02395 c3699e22bf1fb5053b3f5e23ad3c5d07 455 Pfam PF01554 MatE 246 407 5.5E-37 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THERU_02395 c3699e22bf1fb5053b3f5e23ad3c5d07 455 Pfam PF01554 MatE 26 184 6.0E-24 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 301 6.4E-64 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 SUPERFAMILY SSF53686 13 311 2.62E-86 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 TIGRFAM TIGR01138 cysM: cysteine synthase B 18 311 7.4E-144 T 12-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 Gene3D G3DSA:3.40.50.1100 17 308 2.5E-104 T 12-10-2018 THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 Gene3D G3DSA:3.40.50.1100 59 159 2.5E-104 T 12-10-2018 THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 TIGRFAM TIGR01136 cysKM: cysteine synthase 19 312 1.6E-114 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THERU_02455 5b291dbbc89f18cf1201d93dd1ada9d8 315 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 47 65 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 SMART SM00937 64 179 2.3E-55 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 355 1.6E-163 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 Pfam PF03462 PCRF domain 14 204 2.2E-73 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 Gene3D G3DSA:3.30.160.20 211 297 6.4E-102 T 12-10-2018 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 Pfam PF00472 RF-1 domain 212 321 1.4E-42 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 6 357 38.885 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 SUPERFAMILY SSF75620 13 353 7.19E-135 T 12-10-2018 THERU_07605 2d30a5779cdba95b1fede46171c39b09 360 Gene3D G3DSA:3.30.70.1660 112 342 6.4E-102 T 12-10-2018 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 Gene3D G3DSA:3.90.1170.20 13 271 2.4E-106 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 271 8.7E-66 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 PIRSF PIRSF006250 3 276 3.7E-99 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 105 5.4E-26 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 SUPERFAMILY SSF54675 3 106 4.94E-28 T 12-10-2018 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 273 1.7E-106 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 SUPERFAMILY SSF51690 107 273 3.06E-61 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THERU_00995 7bad58bec7f6c3b944f5bab86a28b5c8 277 Gene3D G3DSA:3.20.20.70 121 263 2.4E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Gene3D G3DSA:2.160.10.10 94 303 1.5E-61 T 12-10-2018 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 261 289 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Gene3D G3DSA:3.40.1390.10 1 92 7.5E-6 T 12-10-2018 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 323 3.9E-112 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 320 31.607 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 139 173 1.6E-8 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 216 250 5.6E-5 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 3.5E-8 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_07115 86c7021240116b32992d0dec0a6c1758 323 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 252 286 0.0016 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_07115 86c7021240116b32992d0dec0a6c1758 323 SUPERFAMILY SSF51161 65 309 1.02E-67 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily THERU_03820 839da5f880d994405e535eb1e6650fba 200 SUPERFAMILY SSF64438 22 198 1.78E-44 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic THERU_03820 839da5f880d994405e535eb1e6650fba 200 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 14 194 1.6E-43 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase THERU_03820 839da5f880d994405e535eb1e6650fba 200 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 26 196 4.3E-36 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase THERU_03820 839da5f880d994405e535eb1e6650fba 200 Gene3D G3DSA:3.60.140.10 17 199 2.2E-44 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily THERU_02680 ec616450b19a11cfd561a271d289e35f 508 SUPERFAMILY SSF64153 1 234 1.7E-66 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 203 25.485 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 212 497 21.273 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Gene3D G3DSA:3.40.1190.20 213 496 1.9E-73 T 12-10-2018 IPR029056 Ribokinase-like THERU_02680 ec616450b19a11cfd561a271d289e35f 508 PIRSF PIRSF017184 1 499 1.5E-129 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Pfam PF01256 Carbohydrate kinase 235 489 6.0E-48 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Pfam PF03853 YjeF-related protein N-terminus 26 182 5.8E-47 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 SUPERFAMILY SSF53613 217 494 8.91E-66 T 12-10-2018 IPR029056 Ribokinase-like THERU_02680 ec616450b19a11cfd561a271d289e35f 508 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 432 442 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site THERU_02680 ec616450b19a11cfd561a271d289e35f 508 Gene3D G3DSA:3.40.50.10260 1 210 1.6E-68 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 4 204 7.2E-51 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THERU_02680 ec616450b19a11cfd561a271d289e35f 508 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 221 492 1.8E-60 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 TIGRFAM TIGR00232 tktlase_bact: transketolase 15 660 6.5E-261 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 ProSitePatterns PS00802 Transketolase signature 2. 465 481 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Gene3D G3DSA:3.40.50.970 333 530 1.9E-75 T 12-10-2018 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 SMART SM00861 356 523 2.6E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 338 3.0E-130 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 SUPERFAMILY SSF52922 531 662 9.55E-35 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 ProSitePatterns PS00801 Transketolase signature 1. 20 40 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Pfam PF02780 Transketolase, C-terminal domain 546 654 6.7E-10 T 12-10-2018 IPR033248 Transketolase, C-terminal domain THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Gene3D G3DSA:3.40.50.920 537 662 6.4E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 SUPERFAMILY SSF52518 345 525 3.82E-66 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 SUPERFAMILY SSF52518 12 329 1.28E-106 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Pfam PF02779 Transketolase, pyrimidine binding domain 355 522 1.6E-46 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THERU_07515 64e72564dfd31bef26f87f4e3b1801ca 662 Gene3D G3DSA:3.40.50.970 9 332 6.9E-116 T 12-10-2018 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 Gene3D G3DSA:3.80.30.20 138 368 3.5E-82 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 144 164 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 Pfam PF04055 Radical SAM superfamily 145 314 6.9E-26 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 Pfam PF00919 Uncharacterized protein family UPF0004 2 95 8.3E-24 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 386 3.9E-124 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 Gene3D G3DSA:3.40.50.12160 1 128 3.2E-23 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 SUPERFAMILY SSF102114 138 360 7.46E-56 T 12-10-2018 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 403 9.2E-150 T 12-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 THERU_02835 2696c05778fd9d46c8c16c221b1d06d9 408 SMART SM00729 140 356 6.7E-54 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Gene3D G3DSA:2.40.50.140 1 113 2.3E-42 T 12-10-2018 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 281 5.5E-131 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Gene3D G3DSA:2.30.30.30 125 204 7.0E-35 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 SUPERFAMILY SSF50249 3 117 6.17E-43 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 SMART SM01382 132 259 9.3E-89 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 PIRSF PIRSF002158 4 282 3.8E-104 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 SMART SM01383 42 117 3.7E-42 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 133 257 8.5E-57 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 281 46.149 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 SUPERFAMILY SSF50104 134 276 2.11E-60 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Gene3D G3DSA:4.10.950.10 205 282 6.5E-33 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 2.0E-32 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07350 5d88bf5a5ddc641ec5a52c8dce6ea12a 290 ProSitePatterns PS00467 Ribosomal protein L2 signature. 226 237 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SMART SM00387 477 578 1.3E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SUPERFAMILY SSF47384 370 439 2.16E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 Gene3D G3DSA:1.20.1480.50 220 306 2.2E-16 T 12-10-2018 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 Pfam PF00672 HAMP domain 249 297 2.1E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SMART SM00388 374 444 1.4E-4 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SUPERFAMILY SSF158472 247 299 1.11E-10 T 12-10-2018 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SMART SM00304 247 300 3.9E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 Gene3D G3DSA:1.10.287.130 364 442 7.3E-9 T 12-10-2018 THERU_02915 8c2cba583323eb3f21c7de932307405e 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 479 577 4.9E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_02915 8c2cba583323eb3f21c7de932307405e 580 SUPERFAMILY SSF55874 446 575 2.17E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_02915 8c2cba583323eb3f21c7de932307405e 580 Gene3D G3DSA:3.30.565.10 451 579 1.5E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_02585 803840c73b104bcdd9d0582086242253 573 SUPERFAMILY SSF52540 5 171 3.12E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02585 803840c73b104bcdd9d0582086242253 573 Gene3D G3DSA:1.10.10.10 515 572 1.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_02585 803840c73b104bcdd9d0582086242253 573 Gene3D G3DSA:3.40.50.300 4 171 4.9E-44 T 12-10-2018 THERU_02585 803840c73b104bcdd9d0582086242253 573 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 124 7.2E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_02585 803840c73b104bcdd9d0582086242253 573 Gene3D G3DSA:2.40.30.10 178 291 4.9E-20 T 12-10-2018 THERU_02585 803840c73b104bcdd9d0582086242253 573 SUPERFAMILY SSF46785 531 571 1.45E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_02585 803840c73b104bcdd9d0582086242253 573 Pfam PF00009 Elongation factor Tu GTP binding domain 4 169 1.1E-31 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_02585 803840c73b104bcdd9d0582086242253 573 SUPERFAMILY SSF50447 181 296 2.83E-15 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_02585 803840c73b104bcdd9d0582086242253 573 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site THERU_02585 803840c73b104bcdd9d0582086242253 573 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 6 570 6.5E-132 T 12-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THERU_02585 803840c73b104bcdd9d0582086242253 573 PRINTS PR00315 GTP-binding elongation factor signature 74 85 3.4E-5 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_02585 803840c73b104bcdd9d0582086242253 573 PRINTS PR00315 GTP-binding elongation factor signature 5 18 3.4E-5 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_02585 803840c73b104bcdd9d0582086242253 573 PRINTS PR00315 GTP-binding elongation factor signature 58 68 3.4E-5 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_02585 803840c73b104bcdd9d0582086242253 573 Pfam PF09107 Elongation factor SelB, winged helix 531 570 2.9E-14 T 12-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THERU_08365 0515e9c893b5738d761cf751d033355e 174 Pfam PF13247 4Fe-4S dicluster domain 52 145 3.3E-24 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_08365 0515e9c893b5738d761cf751d033355e 174 Gene3D G3DSA:3.30.70.20 5 153 2.7E-45 T 12-10-2018 THERU_08365 0515e9c893b5738d761cf751d033355e 174 SUPERFAMILY SSF54862 5 161 8.79E-51 T 12-10-2018 THERU_08365 0515e9c893b5738d761cf751d033355e 174 Gene3D G3DSA:3.30.70.20 64 116 2.7E-45 T 12-10-2018 THERU_08365 0515e9c893b5738d761cf751d033355e 174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 Pfam PF00158 Sigma-54 interaction domain 130 291 4.7E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 SUPERFAMILY SSF52540 130 366 8.46E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 149 162 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 Gene3D G3DSA:3.40.50.300 112 295 1.1E-64 T 12-10-2018 THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 338 347 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 SMART SM00382 145 288 1.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 SUPERFAMILY SSF52172 29 168 1.51E-8 T 12-10-2018 IPR011006 CheY-like superfamily THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 SUPERFAMILY SSF46689 338 444 4.93E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 Gene3D G3DSA:1.10.8.60 296 362 1.5E-20 T 12-10-2018 THERU_05000 0f4efea20879dacaf311823fe5b1fc86 452 Gene3D G3DSA:1.10.10.60 363 445 1.2E-9 T 12-10-2018 THERU_06130 4cc8e529784911825d53ba0eb9e8811d 123 Pfam PF13155 Toprim-like 19 88 5.3E-5 T 12-10-2018 THERU_06130 4cc8e529784911825d53ba0eb9e8811d 123 Gene3D G3DSA:3.40.1360.10 1 110 3.9E-28 T 12-10-2018 THERU_06130 4cc8e529784911825d53ba0eb9e8811d 123 SUPERFAMILY SSF110455 2 105 3.92E-28 T 12-10-2018 THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 SUPERFAMILY SSF47240 151 286 1.23E-23 T 12-10-2018 IPR009078 Ferritin-like superfamily THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 Gene3D G3DSA:1.20.1260.10 146 292 1.2E-21 T 12-10-2018 IPR012347 Ferritin-like THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 Pfam PF00210 Ferritin-like domain 7 134 1.3E-9 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 Pfam PF00210 Ferritin-like domain 155 284 2.3E-10 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 Gene3D G3DSA:1.20.1260.10 1 138 1.7E-27 T 12-10-2018 IPR012347 Ferritin-like THERU_01005 0033486cfd5adf3f5368e1fb255a4362 294 SUPERFAMILY SSF47240 1 135 3.22E-24 T 12-10-2018 IPR009078 Ferritin-like superfamily THERU_05545 3f7314b60c230e94016c4a85bb7223af 267 Gene3D G3DSA:3.30.470.10 1 65 1.5E-9 T 12-10-2018 THERU_05545 3f7314b60c230e94016c4a85bb7223af 267 SUPERFAMILY SSF56752 2 215 2.75E-42 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 THERU_05545 3f7314b60c230e94016c4a85bb7223af 267 Gene3D G3DSA:3.20.10.10 92 239 3.1E-29 T 12-10-2018 THERU_05545 3f7314b60c230e94016c4a85bb7223af 267 Pfam PF01063 Amino-transferase class IV 10 215 7.2E-37 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 THERU_04140 7405323217923cda85cc276de304d0d8 378 Pfam PF12704 MacB-like periplasmic core domain 23 215 1.4E-7 T 12-10-2018 IPR025857 MacB-like periplasmic core domain THERU_04140 7405323217923cda85cc276de304d0d8 378 Pfam PF02687 FtsX-like permease family 272 370 3.5E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THERU_03735 bf98aaa7c66a37eabc05c5033ca3de6c 243 TIGRFAM TIGR01204 bioW: 6-carboxyhexanoate--CoA ligase 12 241 2.0E-77 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 THERU_03735 bf98aaa7c66a37eabc05c5033ca3de6c 243 Hamap MF_00668 6-carboxyhexanoate--CoA ligase [bioW]. 1 241 50.675 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 THERU_03735 bf98aaa7c66a37eabc05c5033ca3de6c 243 ProDom PD017229 LIGASE SYNTHASE BIOTIN MAGNESIUM PIMELOYL-COA 6-CARBOXYHEXANOATE--COA BIOSYNTHESIS 6-CARBOXYHEXANOATE-COA BIOW COA 2 215 3.0E-71 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 THERU_03735 bf98aaa7c66a37eabc05c5033ca3de6c 243 Pfam PF03744 6-carboxyhexanoate--CoA ligase 3 240 4.3E-76 T 12-10-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 THERU_07795 1e9237ae9b90463ec806481d5ab2de6b 242 SUPERFAMILY SSF53850 1 240 1.47E-63 T 12-10-2018 THERU_07795 1e9237ae9b90463ec806481d5ab2de6b 242 Gene3D G3DSA:3.40.190.10 3 234 1.7E-60 T 12-10-2018 THERU_07795 1e9237ae9b90463ec806481d5ab2de6b 242 Gene3D G3DSA:3.40.190.10 72 161 1.7E-60 T 12-10-2018 THERU_07795 1e9237ae9b90463ec806481d5ab2de6b 242 Hamap MF_00995 Chorismate dehydratase [mqnA]. 3 242 25.217 T 12-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 THERU_07795 1e9237ae9b90463ec806481d5ab2de6b 242 Pfam PF02621 Menaquinone biosynthesis 3 239 5.1E-47 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme THERU_01375 84d321bd9534613a08e040b10354abbc 90 SMART SM01387 8 88 5.9E-45 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01375 84d321bd9534613a08e040b10354abbc 90 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 78 1.0E-25 T 12-10-2018 THERU_01375 84d321bd9534613a08e040b10354abbc 90 Gene3D G3DSA:1.10.287.10 2 88 6.8E-37 T 12-10-2018 THERU_01375 84d321bd9534613a08e040b10354abbc 90 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.3 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01375 84d321bd9534613a08e040b10354abbc 90 Pfam PF00312 Ribosomal protein S15 8 87 8.6E-36 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01375 84d321bd9534613a08e040b10354abbc 90 SUPERFAMILY SSF47060 3 88 2.74E-35 T 12-10-2018 IPR009068 S15/NS1, RNA-binding THERU_01375 84d321bd9534613a08e040b10354abbc 90 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 88 1.9E-37 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01120 781bb0cd6af62fcc23e65e2ee37700f4 399 SUPERFAMILY SSF53187 157 379 1.57E-47 T 12-10-2018 THERU_01120 781bb0cd6af62fcc23e65e2ee37700f4 399 Gene3D G3DSA:3.40.630.40 132 387 1.3E-67 T 12-10-2018 THERU_01120 781bb0cd6af62fcc23e65e2ee37700f4 399 SMART SM00646 219 376 2.6E-27 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THERU_01120 781bb0cd6af62fcc23e65e2ee37700f4 399 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 159 376 1.4E-47 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 SUPERFAMILY SSF54292 2 77 1.44E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 60 1.0E-6 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 Gene3D G3DSA:1.10.150.120 77 151 1.2E-23 T 12-10-2018 THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 SUPERFAMILY SSF47741 72 149 2.09E-29 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 Gene3D G3DSA:3.10.20.30 1 75 1.4E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_06985 7bf09b92eaca3ae64f3fe27820d21d35 152 Pfam PF01799 [2Fe-2S] binding domain 72 141 1.0E-25 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 Gene3D G3DSA:1.20.1250.20 270 447 4.3E-15 T 12-10-2018 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 499 7.4E-160 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 Pfam PF07690 Major Facilitator Superfamily 22 415 8.7E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 Gene3D G3DSA:1.20.1720.10 18 261 6.4E-44 T 12-10-2018 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 SUPERFAMILY SSF103473 5 425 3.66E-56 T 12-10-2018 IPR036259 MFS transporter superfamily THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.5E-5 T 12-10-2018 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 1.5E-5 T 12-10-2018 THERU_00460 2aed4831f5ce41ad1f75987f1ce73a5a 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 1.5E-5 T 12-10-2018 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 SUPERFAMILY SSF54736 59 130 1.5E-26 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 2.8E-16 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 130 5.4E-52 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 64 130 8.1E-34 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 66 130 2.0E-21 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 130 26.671 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 Gene3D G3DSA:1.20.5.710 4 59 4.3E-21 T 12-10-2018 THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 Gene3D G3DSA:3.30.1390.10 60 130 7.8E-34 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THERU_07290 697a9ff0b346001ffa1fe16ae779052a 130 SUPERFAMILY SSF48300 4 66 7.32E-18 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06465 5319b70874ef866444b113ff70ccfed1 419 Gene3D G3DSA:2.40.160.10 19 303 5.3E-7 T 12-10-2018 IPR023614 Porin domain superfamily THERU_06465 5319b70874ef866444b113ff70ccfed1 419 Pfam PF07396 Phosphate-selective porin O and P 53 219 4.0E-8 T 12-10-2018 IPR010870 Phosphate-selective porin O/P THERU_05660 272f12210fd395991aeed04c62ab2553 400 SUPERFAMILY SSF63867 324 400 1.44E-13 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_05660 272f12210fd395991aeed04c62ab2553 400 Gene3D G3DSA:3.90.105.10 20 169 8.4E-128 T 12-10-2018 THERU_05660 272f12210fd395991aeed04c62ab2553 400 Gene3D G3DSA:2.170.190.11 44 136 8.4E-128 T 12-10-2018 THERU_05660 272f12210fd395991aeed04c62ab2553 400 SUPERFAMILY SSF63882 1 171 3.14E-55 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_05660 272f12210fd395991aeed04c62ab2553 400 Pfam PF00994 Probable molybdopterin binding domain 175 313 1.5E-27 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_05660 272f12210fd395991aeed04c62ab2553 400 SUPERFAMILY SSF53218 170 318 8.51E-36 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily THERU_05660 272f12210fd395991aeed04c62ab2553 400 Gene3D G3DSA:3.40.980.10 170 324 8.4E-128 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily THERU_05660 272f12210fd395991aeed04c62ab2553 400 Gene3D G3DSA:2.40.340.10 325 395 8.4E-128 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_05660 272f12210fd395991aeed04c62ab2553 400 SMART SM00852 175 315 1.5E-38 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_05660 272f12210fd395991aeed04c62ab2553 400 Pfam PF03454 MoeA C-terminal region (domain IV) 329 400 2.2E-14 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_05660 272f12210fd395991aeed04c62ab2553 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 172 311 6.6E-27 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_05660 272f12210fd395991aeed04c62ab2553 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 161 1.0E-47 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_03530 07fdd6082bbea92b62e21986c6255593 426 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 203 281 1.1E-6 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THERU_03530 07fdd6082bbea92b62e21986c6255593 426 SUPERFAMILY SSF90002 203 281 2.48E-6 T 12-10-2018 THERU_03530 07fdd6082bbea92b62e21986c6255593 426 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 162 3.1E-30 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THERU_03530 07fdd6082bbea92b62e21986c6255593 426 Gene3D G3DSA:3.40.50.300 1 192 9.5E-34 T 12-10-2018 THERU_03530 07fdd6082bbea92b62e21986c6255593 426 SUPERFAMILY SSF52540 3 180 9.82E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04460 04c45d6ec9e96527cbeee8a41e804b8c 169 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 10 168 1.3E-29 T 12-10-2018 IPR013343 CRISPR-associated protein Cas4 THERU_04460 04c45d6ec9e96527cbeee8a41e804b8c 169 Pfam PF01930 Domain of unknown function DUF83 10 168 7.0E-52 T 12-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 Gene3D G3DSA:3.40.718.10 2 334 4.8E-127 T 12-10-2018 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 Pfam PF02504 Fatty acid synthesis protein 3 320 4.8E-125 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 137.183 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 332 7.6E-108 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 SUPERFAMILY SSF53659 1 330 3.96E-96 T 12-10-2018 THERU_07825 15f493b44aea6d368cb386f161bbaccc 337 PIRSF PIRSF002465 1 334 1.1E-122 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 Gene3D G3DSA:3.90.1150.10 6 418 1.5E-183 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 2 424 104.519 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 Pfam PF00202 Aminotransferase class-III 32 421 1.2E-78 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 SUPERFAMILY SSF53383 2 421 4.43E-136 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 422 1.1E-199 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THERU_01140 9ef30e3a56a847fdb59e7efa5e8765b6 424 Gene3D G3DSA:3.40.640.10 68 316 1.5E-183 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 285 9.2E-81 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Gene3D G3DSA:3.30.479.20 156 285 9.7E-42 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 SUPERFAMILY SSF54713 52 152 3.01E-23 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Hamap MF_00050 Elongation factor Ts [tsf]. 1 287 66.493 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Gene3D G3DSA:1.10.8.10 1 53 4.1E-25 T 12-10-2018 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 SUPERFAMILY SSF46934 2 53 2.81E-18 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Gene3D G3DSA:3.30.479.20 55 155 2.7E-27 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 ProSitePatterns PS01126 Elongation factor Ts signature 1. 10 25 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 SUPERFAMILY SSF54713 156 285 1.57E-38 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Gene3D G3DSA:1.10.286.20 204 248 9.7E-42 T 12-10-2018 THERU_01905 541ba8677dac45d8f63779faa9bad71c 287 Pfam PF00889 Elongation factor TS 71 285 7.8E-66 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 THERU_01205 c2ec7419a215965838d08e5f0e712f16 404 Pfam PF03772 Competence protein 148 384 5.3E-24 T 12-10-2018 IPR004477 ComEC/Rec2-related protein THERU_01205 c2ec7419a215965838d08e5f0e712f16 404 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 164 326 1.5E-16 T 12-10-2018 IPR004477 ComEC/Rec2-related protein THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 20 89 2.2E-8 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 Gene3D G3DSA:1.10.287.990 21 89 9.6E-10 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 SUPERFAMILY SSF54719 91 207 8.77E-36 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 SUPERFAMILY SSF46609 7 90 2.75E-20 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 PIRSF PIRSF000349 1 205 2.8E-53 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 Gene3D G3DSA:2.40.500.20 90 210 2.5E-31 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_02250 236e38cbdd4be440f2c06fc119ea4f17 211 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 195 4.8E-24 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THERU_04675 4eed0282281ff2df6fc62aa1a53bb664 261 SUPERFAMILY SSF69618 4 258 1.7E-37 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_04675 4eed0282281ff2df6fc62aa1a53bb664 261 Gene3D G3DSA:3.40.50.10090 10 247 2.8E-48 T 12-10-2018 THERU_04675 4eed0282281ff2df6fc62aa1a53bb664 261 Pfam PF02602 Uroporphyrinogen-III synthase HemD 16 245 8.5E-24 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_04675 4eed0282281ff2df6fc62aa1a53bb664 261 Gene3D G3DSA:3.40.50.10090 34 167 2.8E-48 T 12-10-2018 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 SUPERFAMILY SSF101801 240 312 1.44E-16 T 12-10-2018 IPR036429 SpoA-like superfamily THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 PIRSF PIRSF002888 2 315 4.5E-71 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 Gene3D G3DSA:3.40.1550.10 41 229 2.6E-35 T 12-10-2018 IPR028976 CheC-like superfamily THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 Pfam PF02154 Flagellar motor switch protein FliM 35 226 1.7E-36 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 SUPERFAMILY SSF103039 80 226 3.14E-10 T 12-10-2018 IPR028976 CheC-like superfamily THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 243 311 1.3E-20 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 2.5E-13 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 PRINTS PR00955 Flagellar motor switch protein FliM signature 111 130 2.5E-13 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 PRINTS PR00955 Flagellar motor switch protein FliM signature 86 102 2.5E-13 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 PRINTS PR00955 Flagellar motor switch protein FliM signature 208 226 2.5E-13 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THERU_03390 57fa013d363cad3f23a379ba54c01c54 315 Gene3D G3DSA:2.30.330.10 231 314 1.0E-11 T 12-10-2018 IPR036429 SpoA-like superfamily THERU_07100 382a2427807e3642eb46f7a49e60728f 473 Gene3D G3DSA:3.40.640.10 79 306 4.6E-56 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_07100 382a2427807e3642eb46f7a49e60728f 473 Gene3D G3DSA:3.90.1150.10 331 457 4.4E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_07100 382a2427807e3642eb46f7a49e60728f 473 Pfam PF02347 Glycine cleavage system P-protein 42 293 1.7E-13 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THERU_07100 382a2427807e3642eb46f7a49e60728f 473 SUPERFAMILY SSF53383 6 469 1.51E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_00050 7c3e385aab36245963f52d19fcbb7884 216 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 202 4.3E-42 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein THERU_00050 7c3e385aab36245963f52d19fcbb7884 216 Pfam PF03749 Sugar fermentation stimulation protein 12 203 5.2E-53 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein THERU_00050 7c3e385aab36245963f52d19fcbb7884 216 Gene3D G3DSA:2.40.50.580 1 74 1.4E-23 T 12-10-2018 THERU_00050 7c3e385aab36245963f52d19fcbb7884 216 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 212 41.038 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein THERU_00050 7c3e385aab36245963f52d19fcbb7884 216 Gene3D G3DSA:3.40.1350.60 75 211 6.4E-35 T 12-10-2018 THERU_04345 04118f9df416cdf734e06d3177074dc5 67 Pfam PF11127 Protein of unknown function (DUF2892) 2 66 1.3E-11 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 THERU_07560 1e9112b816ae6bd95a984b33d315a004 259 SUPERFAMILY SSF56219 2 258 2.09E-75 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THERU_07560 1e9112b816ae6bd95a984b33d315a004 259 Gene3D G3DSA:3.60.10.10 2 258 1.6E-72 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THERU_07560 1e9112b816ae6bd95a984b33d315a004 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 256 4.5E-76 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THERU_07560 1e9112b816ae6bd95a984b33d315a004 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 250 3.3E-14 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase THERU_07560 1e9112b816ae6bd95a984b33d315a004 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 255 2.3E-77 T 12-10-2018 THERU_02370 f6a8f93734bc18c746d4f9d189cb42c7 138 Gene3D G3DSA:3.40.50.2300 1 137 5.1E-48 T 12-10-2018 THERU_02370 f6a8f93734bc18c746d4f9d189cb42c7 138 SMART SM00226 1 137 6.5E-60 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THERU_02370 f6a8f93734bc18c746d4f9d189cb42c7 138 SUPERFAMILY SSF52788 1 136 2.35E-42 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily THERU_02370 f6a8f93734bc18c746d4f9d189cb42c7 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 134 8.1E-33 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THERU_04555 89a24a1479fc8b02c682f8c0ca15050d 299 Pfam PF11563 Protoglobin 3 154 4.5E-29 T 12-10-2018 THERU_04555 89a24a1479fc8b02c682f8c0ca15050d 299 Pfam PF06146 Phosphate-starvation-inducible E 220 287 2.3E-8 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like THERU_04555 89a24a1479fc8b02c682f8c0ca15050d 299 Gene3D G3DSA:1.10.490.10 1 160 7.6E-41 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 THERU_04555 89a24a1479fc8b02c682f8c0ca15050d 299 SUPERFAMILY SSF46458 4 147 2.21E-28 T 12-10-2018 IPR009050 Globin-like superfamily THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 SUPERFAMILY SSF81464 33 98 8.67E-16 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 164 212 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 Gene3D G3DSA:2.60.40.2600 104 246 7.8E-42 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 PRINTS PR01166 Cytochrome c oxidase subunit II signature 105 124 1.3E-14 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 PRINTS PR01166 Cytochrome c oxidase subunit II signature 183 200 1.3E-14 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 PRINTS PR01166 Cytochrome c oxidase subunit II signature 163 183 1.3E-14 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 PRINTS PR01166 Cytochrome c oxidase subunit II signature 201 218 1.3E-14 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 PRINTS PR01166 Cytochrome c oxidase subunit II signature 71 83 1.3E-14 T 12-10-2018 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 Gene3D G3DSA:1.10.287.90 13 101 1.7E-20 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 32 228 1.4E-51 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 95 2.3E-10 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 112 218 9.5E-17 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00820 5ee02daff0d92db4320e554fbd53f456 247 SUPERFAMILY SSF49503 103 237 2.75E-38 T 12-10-2018 IPR008972 Cupredoxin THERU_06510 d19a319f4f582eea96f3cb82a99ccbd8 235 SUPERFAMILY SSF52467 38 181 4.9E-9 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THERU_06510 d19a319f4f582eea96f3cb82a99ccbd8 235 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 23 178 7.6E-47 T 12-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 THERU_04535 72db732c5242f6bd4a5a0e0a2a01811e 66 Pfam PF00830 Ribosomal L28 family 3 58 7.0E-18 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_04535 72db732c5242f6bd4a5a0e0a2a01811e 66 SUPERFAMILY SSF143800 1 64 1.2E-18 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_04535 72db732c5242f6bd4a5a0e0a2a01811e 66 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.2E-18 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_04535 72db732c5242f6bd4a5a0e0a2a01811e 66 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 14.457 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_04535 72db732c5242f6bd4a5a0e0a2a01811e 66 Gene3D G3DSA:2.30.170.40 18 66 1.3E-17 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00160 7ca9e182510d7162914b2a2670430da8 138 SUPERFAMILY SSF75169 33 137 1.02E-10 T 12-10-2018 IPR027396 DsrEFH-like THERU_00160 7ca9e182510d7162914b2a2670430da8 138 Gene3D G3DSA:3.40.1260.10 27 135 1.0E-22 T 12-10-2018 IPR027396 DsrEFH-like THERU_00160 7ca9e182510d7162914b2a2670430da8 138 Pfam PF02635 DsrE/DsrF-like family 30 137 7.8E-9 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 SUPERFAMILY SSF56059 1 230 3.98E-44 T 12-10-2018 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 Gene3D G3DSA:3.30.1490.20 22 97 6.9E-51 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 Pfam PF16114 ATP citrate lyase citrate-binding 260 397 2.2E-13 T 12-10-2018 IPR032263 ATP-citrate synthase, citrate-binding domain KEGG: 00020+2.3.3.8|KEGG: 00720+2.3.3.8|MetaCyc: PWY-5172|Reactome: R-HSA-163765|Reactome: R-HSA-6798695|Reactome: R-HSA-75105 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 Pfam PF08442 ATP-grasp domain 2 195 1.4E-38 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 SUPERFAMILY SSF52210 252 391 6.54E-24 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 PIRSF PIRSF001554 1 409 1.0E-100 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 Gene3D G3DSA:3.40.50.261 236 390 3.2E-32 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06630 f15d97a2fd002b576d3f577a043552d1 429 Gene3D G3DSA:3.30.470.20 1 219 6.9E-51 T 12-10-2018 THERU_00745 41062822c94235dbd860679acb9508e1 110 Gene3D G3DSA:3.40.30.10 1 110 2.2E-37 T 12-10-2018 THERU_00745 41062822c94235dbd860679acb9508e1 110 SUPERFAMILY SSF52833 4 105 3.13E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_06035 4239b4c765da049bfa1a3ec0abfc7775 193 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 4 189 1.4E-68 T 12-10-2018 IPR014856 PIN-domain ribonuclease THERU_06035 4239b4c765da049bfa1a3ec0abfc7775 193 Pfam PF08745 PINc domain ribonuclease 4 189 2.1E-67 T 12-10-2018 IPR014856 PIN-domain ribonuclease THERU_06035 4239b4c765da049bfa1a3ec0abfc7775 193 SUPERFAMILY SSF88723 3 187 5.61E-8 T 12-10-2018 IPR029060 PIN-like domain superfamily THERU_06035 4239b4c765da049bfa1a3ec0abfc7775 193 Hamap MF_01078 UPF0278 protein . 1 193 31.915 T 12-10-2018 IPR014856 PIN-domain ribonuclease THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 240 29.927 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 Gene3D G3DSA:3.30.70.660 107 238 2.3E-31 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 Pfam PF01416 tRNA pseudouridine synthase 145 238 5.3E-15 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 SUPERFAMILY SSF55120 1 239 1.21E-65 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 Gene3D G3DSA:3.30.70.580 1 105 1.6E-29 T 12-10-2018 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 PIRSF PIRSF001430 1 240 1.5E-64 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_07615 dac94a84d1a4f589c3efc3b33762bf34 240 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 6 234 2.6E-45 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 Gene3D G3DSA:3.30.950.10 111 225 9.8E-37 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 SUPERFAMILY SSF53790 1 220 1.31E-74 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 Gene3D G3DSA:3.40.1010.10 1 110 3.5E-43 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 219 2.0E-68 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 PIRSF PIRSF005917 1 225 1.8E-90 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 222 35.713 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THERU_04310 8748a0aca932dd1b8af57174bfdbb41f 225 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 199 9.8E-30 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 SMART SM00838 394 483 0.0031 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Gene3D G3DSA:3.30.70.870 281 362 7.1E-33 T 12-10-2018 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Gene3D G3DSA:3.40.50.300 1 180 8.3E-74 T 12-10-2018 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 SUPERFAMILY SSF54980 395 490 1.68E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.7E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 PRINTS PR00315 GTP-binding elongation factor signature 69 79 2.7E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 PRINTS PR00315 GTP-binding elongation factor signature 121 130 2.7E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.7E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 PRINTS PR00315 GTP-binding elongation factor signature 85 96 2.7E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Pfam PF03144 Elongation factor Tu domain 2 200 270 2.0E-13 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Hamap MF_00071 Elongation factor 4 [lepA]. 1 592 287.452 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 SUPERFAMILY SSF54980 286 365 1.08E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 170 5.0E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 SUPERFAMILY SSF50447 160 283 2.08E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 SUPERFAMILY SSF52540 2 200 6.35E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Gene3D G3DSA:3.30.70.2570 476 550 1.0E-32 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Pfam PF00679 Elongation factor G C-terminus 395 476 9.2E-23 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Gene3D G3DSA:3.30.70.3380 363 475 5.4E-44 T 12-10-2018 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 TIGRFAM TIGR01393 lepA: elongation factor 4 3 592 5.6E-300 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Gene3D G3DSA:2.40.30.10 181 280 1.9E-39 T 12-10-2018 THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Pfam PF06421 GTP-binding protein LepA C-terminus 484 590 6.2E-50 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal THERU_04245 c541fb6ea03884b6e3886f61ab6d2398 592 Pfam PF00009 Elongation factor Tu GTP binding domain 3 176 5.2E-55 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 Pfam PF00875 DNA photolyase 25 177 2.0E-11 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 Gene3D G3DSA:1.10.579.10 315 456 3.1E-71 T 12-10-2018 THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 SUPERFAMILY SSF52425 23 188 9.16E-21 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 SUPERFAMILY SSF48173 218 452 1.7E-62 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 Gene3D G3DSA:3.40.50.620 2 145 3.6E-27 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01960 2c4177c5677c7de4dae762850e4c5394 456 Gene3D G3DSA:1.25.40.80 147 313 1.0E-47 T 12-10-2018 THERU_03155 d9fa453273af847e8caeef7617918cdf 312 Gene3D G3DSA:1.10.3720.10 63 311 5.4E-33 T 12-10-2018 IPR035906 MetI-like superfamily THERU_03155 d9fa453273af847e8caeef7617918cdf 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 301 2.6E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_03155 d9fa453273af847e8caeef7617918cdf 312 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 16 305 3.2E-91 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 THERU_03155 d9fa453273af847e8caeef7617918cdf 312 SUPERFAMILY SSF161098 19 298 1.31E-36 T 12-10-2018 IPR035906 MetI-like superfamily THERU_01405 81d1226a2893c4ff14b87e84a9e72620 146 Gene3D G3DSA:3.10.490.10 1 141 2.3E-11 T 12-10-2018 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 117 27.912 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 PIRSF PIRSF002191 2 124 1.3E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 116 1.1E-44 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 PRINTS PR00061 Ribosomal protein L19 signature 5 34 1.2E-29 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 PRINTS PR00061 Ribosomal protein L19 signature 65 88 1.2E-29 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 PRINTS PR00061 Ribosomal protein L19 signature 35 64 1.2E-29 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 SUPERFAMILY SSF50104 6 109 1.6E-40 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 Pfam PF01245 Ribosomal protein L19 5 109 4.2E-42 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 ProSitePatterns PS01015 Ribosomal protein L19 signature. 87 102 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06565 67103a25fd1be512ff8fc6a25ce9147e 124 Gene3D G3DSA:2.30.30.790 10 116 2.3E-18 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.6E-22 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.6E-22 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.6E-22 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 PIRSF PIRSF004669 1 89 1.2E-30 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.1E-26 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THERU_08265 2e39a2a43d66876a2c2cd225a2106ed2 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 1.1E-29 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Gene3D G3DSA:2.160.20.60 1227 1488 1.7E-99 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 SUPERFAMILY SSF51395 438 1194 8.7E-248 T 12-10-2018 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Pfam PF04898 Glutamate synthase central domain 446 754 7.9E-109 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 SUPERFAMILY SSF56235 9 421 4.34E-134 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Gene3D G3DSA:3.60.20.10 9 534 0.0 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Pfam PF00310 Glutamine amidotransferases class-II 9 418 1.9E-158 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Pfam PF01645 Conserved region in glutamate synthase 816 1174 9.8E-151 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Pfam PF01493 GXGXG motif 1253 1437 2.1E-71 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 SUPERFAMILY SSF69336 1228 1477 2.22E-87 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Gene3D G3DSA:3.20.20.70 472 1188 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03220 16c7118d89a518030675c1d07cd99d52 1496 Gene3D G3DSA:3.20.20.70 423 810 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 Gene3D G3DSA:3.30.310.70 30 152 9.7E-13 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 Gene3D G3DSA:3.30.310.70 179 290 4.6E-8 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 SUPERFAMILY SSF103247 179 291 3.53E-17 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 SUPERFAMILY SSF103247 33 152 1.57E-15 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 Pfam PF03625 Domain of unknown function DUF302 59 118 2.0E-7 T 12-10-2018 IPR005180 Domain of unknown function DUF302 THERU_04695 5048402c1afad0b15f5f7df8141cfa23 294 Pfam PF03625 Domain of unknown function DUF302 208 257 6.3E-10 T 12-10-2018 IPR005180 Domain of unknown function DUF302 THERU_00125 410e84c94f2ebdc436ebde1e0c28102e 410 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 1 178 35.292 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 THERU_00125 410e84c94f2ebdc436ebde1e0c28102e 410 Pfam PF02677 Uncharacterized BCR, COG1636 1 174 9.3E-62 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 THERU_05860 e0c35fa47f3bc86b6128e3cca3218457 187 Gene3D G3DSA:2.160.20.70 80 187 4.4E-41 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 THERU_05860 e0c35fa47f3bc86b6128e3cca3218457 187 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 1 187 17.793 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THERU_05860 e0c35fa47f3bc86b6128e3cca3218457 187 SUPERFAMILY SSF63848 83 186 3.79E-31 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 THERU_05860 e0c35fa47f3bc86b6128e3cca3218457 187 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 71 186 1.9E-34 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THERU_05860 e0c35fa47f3bc86b6128e3cca3218457 187 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 85 184 5.7E-31 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THERU_04025 788459197f2d20a57b0a01184e5921a8 399 Pfam PF00534 Glycosyl transferases group 1 188 381 2.2E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_04025 788459197f2d20a57b0a01184e5921a8 399 Gene3D G3DSA:3.40.50.2000 183 386 4.2E-41 T 12-10-2018 THERU_04025 788459197f2d20a57b0a01184e5921a8 399 Gene3D G3DSA:3.40.50.2000 3 178 2.2E-11 T 12-10-2018 THERU_04025 788459197f2d20a57b0a01184e5921a8 399 Pfam PF13439 Glycosyltransferase Family 4 15 170 2.1E-9 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_04025 788459197f2d20a57b0a01184e5921a8 399 SUPERFAMILY SSF53756 7 398 1.57E-60 T 12-10-2018 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 502 1.0E-261 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 372 497 3.0E-50 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 93 3.4E-17 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 SUPERFAMILY SSF50615 11 95 8.89E-28 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 356 365 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Gene3D G3DSA:3.40.50.300 95 372 1.9E-128 T 12-10-2018 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 365 1.8E-76 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 SUPERFAMILY SSF52540 97 371 1.26E-102 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 502 51.928 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Gene3D G3DSA:2.40.30.20 2 94 1.9E-31 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 SUPERFAMILY SSF47917 373 501 2.88E-48 T 12-10-2018 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 PIRSF PIRSF039088 2 503 9.1E-256 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05560 91f43ab35c390428e4cc5ff0e5c85ad1 503 Gene3D G3DSA:1.20.150.20 373 503 1.1E-53 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03370 e588d2c38b65e8a325915c92a3d26079 123 PIRSF PIRSF002889 7 121 1.6E-20 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 THERU_03370 e588d2c38b65e8a325915c92a3d26079 123 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 13 119 4.2E-20 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 THERU_06040 53f88abcba094a4a62bcedc88957cfdc 114 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 11 113 1.7E-34 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THERU_06040 53f88abcba094a4a62bcedc88957cfdc 114 SUPERFAMILY SSF89360 5 99 4.9E-28 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THERU_06040 53f88abcba094a4a62bcedc88957cfdc 114 Gene3D G3DSA:2.60.300.12 9 113 1.7E-33 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THERU_06040 53f88abcba094a4a62bcedc88957cfdc 114 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 94 111 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 THERU_06040 53f88abcba094a4a62bcedc88957cfdc 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 11 109 1.3E-16 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 SMART SM00851 12 126 1.6E-40 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Pfam PF02142 MGS-like domain 13 125 2.3E-20 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain THERU_01820 a49233f852d6de55e81dcda65f726c50 505 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 505 6.2E-172 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Gene3D G3DSA:3.40.50.1380 1 191 3.3E-78 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THERU_01820 a49233f852d6de55e81dcda65f726c50 505 PIRSF PIRSF000414 1 505 1.5E-203 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Pfam PF01808 AICARFT/IMPCHase bienzyme 132 436 1.3E-109 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 505 40.411 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Gene3D G3DSA:3.40.140.20 368 505 1.9E-58 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 SUPERFAMILY SSF53927 206 505 2.81E-119 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 SUPERFAMILY SSF52335 2 190 2.52E-57 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THERU_01820 a49233f852d6de55e81dcda65f726c50 505 Gene3D G3DSA:3.40.140.20 201 352 7.1E-57 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01820 a49233f852d6de55e81dcda65f726c50 505 SMART SM00798 131 437 5.0E-168 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 ProSitePatterns PS00447 DNA polymerase family A signature. 406 425 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Gene3D G3DSA:3.30.420.10 1 184 1.2E-34 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 SMART SM00482 338 540 3.5E-73 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Gene3D G3DSA:1.20.1060.10 208 308 2.4E-8 T 12-10-2018 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 SMART SM00474 3 166 9.1E-38 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Gene3D G3DSA:3.30.70.370 321 575 3.4E-73 T 12-10-2018 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Pfam PF00476 DNA polymerase family A 216 576 6.7E-86 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Gene3D G3DSA:1.10.150.20 361 500 3.4E-73 T 12-10-2018 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 SUPERFAMILY SSF53098 2 168 1.02E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 Pfam PF01612 3'-5' exonuclease 4 165 2.5E-32 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 SUPERFAMILY SSF56672 194 577 3.67E-97 T 12-10-2018 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 PRINTS PR00868 DNA-polymerase family A (pol I) signature 493 509 5.0E-25 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 PRINTS PR00868 DNA-polymerase family A (pol I) signature 313 335 5.0E-25 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 PRINTS PR00868 DNA-polymerase family A (pol I) signature 523 536 5.0E-25 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_02435 e8161fbd415d8d89dd55ac76d0af3d7b 578 PRINTS PR00868 DNA-polymerase family A (pol I) signature 406 431 5.0E-25 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Gene3D G3DSA:3.30.110.120 249 366 4.3E-154 T 12-10-2018 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 ProSitePatterns PS00150 Acylphosphatase signature 1. 7 17 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 733 6.4E-265 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Pfam PF07503 HypF finger 103 136 1.2E-17 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Pfam PF07503 HypF finger 153 186 2.6E-17 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 SUPERFAMILY SSF55821 170 386 1.77E-52 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Gene3D G3DSA:3.30.420.350 482 721 1.3E-131 T 12-10-2018 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 SUPERFAMILY SSF53067 218 715 3.15E-6 T 12-10-2018 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Gene3D G3DSA:3.30.420.360 378 733 1.3E-131 T 12-10-2018 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Pfam PF01300 Telomere recombination 206 378 3.7E-55 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 PIRSF PIRSF006256 1 738 0.0 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 SUPERFAMILY SSF54975 2 85 1.13E-22 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Pfam PF00708 Acylphosphatase 4 84 2.3E-19 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_04875 e5b6c674d29cd79889f5bf1a7e9a7e50 739 Gene3D G3DSA:3.90.870.50 5 357 4.3E-154 T 12-10-2018 THERU_04180 d39afe4f0ca22bd15f23981f2df5be88 163 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 77 149 5.4E-7 T 12-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 Gene3D G3DSA:1.10.20.140 110 181 5.6E-93 T 12-10-2018 THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 Gene3D G3DSA:3.40.50.300 11 276 5.6E-93 T 12-10-2018 THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 276 3.9E-86 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 SUPERFAMILY SSF52540 9 146 3.29E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 293 28.523 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 Pfam PF01715 IPP transferase 40 276 1.2E-74 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THERU_01235 47a9f13502b79b27d665cbfe4278ba4a 319 SUPERFAMILY SSF52540 6 299 7.64E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 TIGRFAM TIGR01054 rgy: reverse gyrase 1 1137 0.0 T 12-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SMART SM00487 68 297 1.6E-18 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SUPERFAMILY SSF52540 308 571 1.03E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:3.40.50.300 51 287 2.8E-76 T 12-10-2018 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:3.40.50.140 594 744 6.1E-33 T 12-10-2018 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Pfam PF00270 DEAD/DEAH box helicase 74 202 7.2E-9 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SMART SM00493 593 714 3.7E-33 T 12-10-2018 IPR006171 TOPRIM domain THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:3.40.50.300 498 580 2.5E-13 T 12-10-2018 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:3.40.50.300 290 481 8.9E-28 T 12-10-2018 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Hamap MF_01125 Reverse gyrase [rgy]. 1 1140 61.734 T 12-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:1.10.460.10 745 1133 1.6E-138 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:2.60.510.20 796 1037 1.6E-138 T 12-10-2018 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Gene3D G3DSA:1.10.290.10 850 973 1.6E-138 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SUPERFAMILY SSF56712 590 1136 9.29E-142 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SUPERFAMILY SSF52540 56 225 1.24E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Pfam PF01131 DNA topoisomerase 739 1129 8.9E-90 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SMART SM00436 715 800 9.0E-43 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 688 701 3.4E-30 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 882 891 3.4E-30 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1053 1067 3.4E-30 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 962 978 3.4E-30 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 774 792 3.4E-30 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 SMART SM00437 840 1090 1.8E-95 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THERU_06885 f9793c2f898c3107306fab97764b31e4 1145 Pfam PF01751 Toprim domain 595 724 1.8E-27 T 12-10-2018 IPR006171 TOPRIM domain THERU_04725 16ff4b746e8e5abb88ebf80d9378b176 137 SUPERFAMILY SSF52833 6 133 3.29E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_04725 16ff4b746e8e5abb88ebf80d9378b176 137 Gene3D G3DSA:3.40.30.10 22 133 4.0E-22 T 12-10-2018 THERU_04725 16ff4b746e8e5abb88ebf80d9378b176 137 Pfam PF13098 Thioredoxin-like domain 34 110 1.8E-10 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_07395 1f401163a24ecf14f9063b45de27d879 568 SUPERFAMILY SSF56425 228 347 8.67E-44 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Gene3D G3DSA:3.50.50.60 5 400 1.4E-159 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_07395 1f401163a24ecf14f9063b45de27d879 568 SUPERFAMILY SSF46977 434 568 1.1E-50 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Gene3D G3DSA:1.20.58.100 415 530 4.6E-38 T 12-10-2018 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 PIRSF PIRSF000171 1 565 4.3E-54 T 12-10-2018 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Gene3D G3DSA:4.10.80.40 531 564 4.1E-6 T 12-10-2018 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Pfam PF02910 Fumarate reductase flavoprotein C-term 443 568 2.5E-43 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Gene3D G3DSA:3.90.700.10 238 342 1.4E-159 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 SUPERFAMILY SSF51905 3 415 1.66E-77 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_07395 1f401163a24ecf14f9063b45de27d879 568 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 5 568 4.1E-256 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_07395 1f401163a24ecf14f9063b45de27d879 568 Pfam PF00890 FAD binding domain 5 389 4.1E-114 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 10 472 96.021 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 Gene3D G3DSA:3.90.1300.10 1 479 1.1E-204 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 471 1.7E-206 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 SUPERFAMILY SSF75304 3 470 3.66E-163 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 Pfam PF01425 Amidase 23 461 3.2E-168 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THERU_01105 5a0aea8cf8490429c88fc84501ef58e7 479 ProSitePatterns PS00571 Amidases signature. 148 179 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 THERU_05510 23121c5eb8298987a7bf192587b69eb7 210 Gene3D G3DSA:3.30.420.10 27 204 2.2E-31 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THERU_05510 23121c5eb8298987a7bf192587b69eb7 210 SMART SM00479 36 200 4.9E-22 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THERU_05510 23121c5eb8298987a7bf192587b69eb7 210 SUPERFAMILY SSF53098 28 200 2.7E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_05510 23121c5eb8298987a7bf192587b69eb7 210 Pfam PF00929 Exonuclease 38 190 9.2E-20 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THERU_00960 216af705dc57597d9756ff9f45988788 156 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 13 151 1.4E-62 T 12-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 THERU_00960 216af705dc57597d9756ff9f45988788 156 Pfam PF01467 Cytidylyltransferase-like 24 114 9.1E-17 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_00960 216af705dc57597d9756ff9f45988788 156 SUPERFAMILY SSF52374 19 149 1.58E-28 T 12-10-2018 THERU_00960 216af705dc57597d9756ff9f45988788 156 Gene3D G3DSA:3.40.50.620 3 155 1.7E-43 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_00960 216af705dc57597d9756ff9f45988788 156 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 87 3.7E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 SUPERFAMILY SSF55190 2 89 1.31E-14 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 2 82 1.8E-14 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 SMART SM01016 3 82 4.9E-20 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 SMART SM00836 429 551 4.3E-29 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Gene3D G3DSA:3.40.50.620 111 423 8.2E-161 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 551 25.6 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 121 130 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Gene3D G3DSA:1.10.730.10 424 551 8.2E-161 T 12-10-2018 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Gene3D G3DSA:3.30.1360.70 1 107 2.3E-19 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 1 551 5.1E-126 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 126 142 1.2E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.2E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 111 126 1.2E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 PRINTS PR01038 Arginyl-tRNA synthetase signature 150 163 1.2E-24 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 SUPERFAMILY SSF52374 106 439 1.04E-94 T 12-10-2018 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Pfam PF00750 tRNA synthetases class I (R) 104 398 9.4E-23 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 Pfam PF05746 DALR anticodon binding domain 429 551 1.8E-25 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THERU_05475 a6602db3e332967a54a0e5ae0b9c52f4 551 SUPERFAMILY SSF47323 424 551 1.83E-27 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02580 daa7173019d8dee21b45a67b4f709792 301 SUPERFAMILY SSF46785 5 80 2.3E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_02580 daa7173019d8dee21b45a67b4f709792 301 Gene3D G3DSA:3.40.190.290 95 297 1.3E-30 T 12-10-2018 THERU_02580 daa7173019d8dee21b45a67b4f709792 301 Pfam PF03466 LysR substrate binding domain 92 294 2.2E-32 T 12-10-2018 IPR005119 LysR, substrate-binding THERU_02580 daa7173019d8dee21b45a67b4f709792 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.4E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THERU_02580 daa7173019d8dee21b45a67b4f709792 301 SUPERFAMILY SSF53850 94 294 6.62E-30 T 12-10-2018 THERU_02580 daa7173019d8dee21b45a67b4f709792 301 Gene3D G3DSA:1.10.10.10 6 94 7.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 183 1.4E-61 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 50.775 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 SUPERFAMILY SSF53850 3 204 5.79E-63 T 12-10-2018 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 Pfam PF01634 ATP phosphoribosyltransferase 51 204 1.4E-50 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 Gene3D G3DSA:3.40.190.10 92 176 9.3E-72 T 12-10-2018 THERU_01655 2d01455a2daaa3a2a0eba2e68994c9e0 219 Gene3D G3DSA:3.40.190.10 6 196 9.3E-72 T 12-10-2018 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 409 27.937 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 SUPERFAMILY SSF53244 274 405 4.58E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Gene3D G3DSA:3.40.1190.10 55 270 2.5E-47 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Gene3D G3DSA:3.90.190.20 273 412 1.1E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Pfam PF01225 Mur ligase family, catalytic domain 1 68 8.7E-10 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 SUPERFAMILY SSF63418 1 69 1.57E-18 T 12-10-2018 IPR035911 MurE/MurF, N-terminal THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Pfam PF02875 Mur ligase family, glutamate ligase domain 274 349 6.6E-15 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 1 406 2.2E-124 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Pfam PF08245 Mur ligase middle domain 79 253 1.0E-30 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 SUPERFAMILY SSF53623 75 272 1.24E-35 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THERU_07835 1fe2937d00658bb6a5ef6d08de17b4e4 415 Gene3D G3DSA:3.40.1390.10 1 50 7.0E-20 T 12-10-2018 THERU_00785 d5c7eb3b916185c365adffea2934e9a6 277 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 1 257 8.1E-88 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 THERU_00785 d5c7eb3b916185c365adffea2934e9a6 277 Gene3D G3DSA:3.40.50.1580 1 277 1.2E-96 T 12-10-2018 THERU_00785 d5c7eb3b916185c365adffea2934e9a6 277 Pfam PF01048 Phosphorylase superfamily 2 257 1.3E-50 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THERU_00785 d5c7eb3b916185c365adffea2934e9a6 277 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 277 39.142 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 THERU_00785 d5c7eb3b916185c365adffea2934e9a6 277 SUPERFAMILY SSF53167 1 275 4.45E-84 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 THERU_00625 1e4d309292f1a19ca8a40aa3261e5ab7 66 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 55 3.9E-9 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal THERU_02300 89976ab6dcdc1ca61e348636c5512d75 106 Pfam PF02641 Uncharacterized ACR, COG1993 8 103 2.2E-40 T 12-10-2018 IPR003793 Domain of unknown function DUF190 THERU_02300 89976ab6dcdc1ca61e348636c5512d75 106 Gene3D G3DSA:3.30.70.120 1 106 2.4E-43 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THERU_02300 89976ab6dcdc1ca61e348636c5512d75 106 SUPERFAMILY SSF54913 5 104 2.82E-35 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 SUPERFAMILY SSF55120 71 309 9.59E-70 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 SUPERFAMILY SSF55174 12 100 1.16E-12 T 12-10-2018 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 Pfam PF00849 RNA pseudouridylate synthase 87 243 2.9E-29 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 Pfam PF01479 S4 domain 14 60 4.7E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 Gene3D G3DSA:3.10.290.10 7 67 2.3E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 Gene3D G3DSA:3.30.2350.10 70 297 4.4E-66 T 12-10-2018 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 SMART SM00363 13 78 6.5E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_03320 0a98a336d5dd7e67ed722108053aeda4 311 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 309 1.5E-82 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 101 1.1E-40 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 322 3.5E-135 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 SMART SM00846 2 151 1.8E-94 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 2.1E-69 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 SUPERFAMILY SSF55347 151 313 8.33E-72 T 12-10-2018 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 Gene3D G3DSA:3.30.360.10 150 320 1.6E-156 T 12-10-2018 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 SUPERFAMILY SSF51735 2 167 2.87E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PIRSF PIRSF000149 1 332 2.0E-132 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 Gene3D G3DSA:3.40.50.720 3 326 1.6E-156 T 12-10-2018 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 7.6E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 7.6E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 7.6E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 7.6E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02805 3385020b2d5f95cb8b8a7c3c07cfc6a6 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 7.6E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Gene3D G3DSA:1.25.40.10 29 84 4.5E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Gene3D G3DSA:3.30.420.40 312 418 2.4E-22 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Gene3D G3DSA:1.25.40.10 165 310 8.8E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Pfam PF00515 Tetratricopeptide repeat 171 202 4.6E-9 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Gene3D G3DSA:3.30.420.150 419 552 2.4E-22 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SUPERFAMILY SSF53067 308 432 2.53E-13 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 251 284 1.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 94 127 0.18 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 171 204 1.3E-7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 57 90 1.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 134 167 8.1E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 211 244 17.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SMART SM00028 27 56 29.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Pfam PF13432 Tetratricopeptide repeat 35 83 0.006 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 SUPERFAMILY SSF81901 33 280 7.85E-29 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Gene3D G3DSA:1.25.40.10 85 164 4.5E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Pfam PF13424 Tetratricopeptide repeat 210 283 5.4E-14 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Pfam PF13424 Tetratricopeptide repeat 94 164 1.2E-12 T 12-10-2018 THERU_00635 b12ca38925933cb0d0a5fcda9a137398 643 Pfam PF02541 Ppx/GppA phosphatase family 335 510 2.8E-19 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 THERU_06370 b68b409e5aae270f93654b451df8043b 368 PIRSF PIRSF015578 1 366 1.2E-94 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 THERU_06370 b68b409e5aae270f93654b451df8043b 368 Pfam PF01658 Myo-inositol-1-phosphate synthase 200 308 2.5E-32 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 THERU_06370 b68b409e5aae270f93654b451df8043b 368 Gene3D G3DSA:3.40.50.720 5 361 2.0E-118 T 12-10-2018 THERU_06370 b68b409e5aae270f93654b451df8043b 368 SUPERFAMILY SSF51735 4 364 2.94E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06370 b68b409e5aae270f93654b451df8043b 368 SUPERFAMILY SSF55347 198 308 1.05E-36 T 12-10-2018 THERU_06370 b68b409e5aae270f93654b451df8043b 368 Gene3D G3DSA:3.30.360.10 199 308 2.0E-118 T 12-10-2018 THERU_01300 69dbff679e062a15584b69486969294d 118 SUPERFAMILY SSF74731 4 115 2.22E-45 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 Pfam PF00453 Ribosomal protein L20 4 106 4.7E-45 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 PRINTS PR00062 Ribosomal protein L20 signature 40 69 4.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 PRINTS PR00062 Ribosomal protein L20 signature 73 99 4.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 PRINTS PR00062 Ribosomal protein L20 signature 10 39 4.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 Gene3D G3DSA:1.10.720.90 2 53 5.7E-17 T 12-10-2018 THERU_01300 69dbff679e062a15584b69486969294d 118 Gene3D G3DSA:1.10.1900.20 54 118 9.6E-31 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 0.001 T 12-10-2018 THERU_01300 69dbff679e062a15584b69486969294d 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 112 4.4E-47 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 1 113 28.868 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01300 69dbff679e062a15584b69486969294d 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 52 68 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Pfam PF13365 Trypsin-like peptidase domain 96 237 5.8E-29 T 12-10-2018 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 SMART SM00228 379 460 2.9E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 SMART SM00228 273 353 3.7E-20 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 377 436 1.0E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Gene3D G3DSA:2.30.42.10 380 468 6.8E-20 T 12-10-2018 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 SUPERFAMILY SSF50156 380 468 1.97E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 108 120 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 129 149 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 311 323 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 PRINTS PR00834 HtrA/DegQ protease family signature 174 198 2.0E-49 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 SUPERFAMILY SSF50494 51 265 2.79E-60 T 12-10-2018 IPR009003 Peptidase S1, PA clan THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 SUPERFAMILY SSF50156 254 360 1.97E-28 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Gene3D G3DSA:2.40.10.120 50 266 1.1E-72 T 12-10-2018 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Pfam PF13180 PDZ domain 273 362 8.8E-21 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 Gene3D G3DSA:2.30.42.10 268 370 1.2E-31 T 12-10-2018 THERU_07975 6394e2a0c3185748e4734f3fd8c7b3a3 470 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 51 466 1.3E-139 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 SUPERFAMILY SSF53067 101 304 6.73E-43 T 12-10-2018 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 SUPERFAMILY SSF53067 3 121 1.12E-26 T 12-10-2018 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 Pfam PF00814 Glycoprotease family 24 302 2.9E-93 T 12-10-2018 IPR000905 Gcp-like domain THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 Gene3D G3DSA:3.30.420.40 4 310 6.4E-117 T 12-10-2018 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 Gene3D G3DSA:3.30.420.40 128 288 6.4E-117 T 12-10-2018 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 153 174 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 258 267 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 130 142 1.5E-45 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 301 3.0E-100 T 12-10-2018 IPR017861 Kae1/TsaD family THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 326 61.953 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 THERU_00645 c3c4d0fce34c77f68a6d29f794caaa26 334 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 309 1.9E-118 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 Pfam PF13537 Glutamine amidotransferase domain 51 168 1.7E-45 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 Gene3D G3DSA:3.60.20.10 2 185 1.1E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 SUPERFAMILY SSF56235 1 226 3.52E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 SUPERFAMILY SSF52402 241 633 6.17E-83 T 12-10-2018 THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 PIRSF PIRSF001589 1 641 3.4E-161 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 573 3.5E-145 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THERU_04020 dbb57f6356b19f49a67c1f1941d52bf0 641 Pfam PF00733 Asparagine synthase 251 637 2.1E-100 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THERU_03680 b34d14354bf313269ba4543c148db244 148 Pfam PF02502 Ribose/Galactose Isomerase 3 139 9.4E-61 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 THERU_03680 b34d14354bf313269ba4543c148db244 148 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 3.6E-63 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 THERU_03680 b34d14354bf313269ba4543c148db244 148 Gene3D G3DSA:3.40.1400.10 1 146 2.2E-67 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 THERU_03680 b34d14354bf313269ba4543c148db244 148 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 4.5E-70 T 12-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 THERU_03680 b34d14354bf313269ba4543c148db244 148 SUPERFAMILY SSF89623 1 144 1.44E-62 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 THERU_03680 b34d14354bf313269ba4543c148db244 148 PIRSF PIRSF005384 1 146 5.1E-65 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 Pfam PF01018 GTP1/OBG 3 157 4.2E-61 T 12-10-2018 IPR006169 GTP1/OBG domain THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 Hamap MF_01454 GTPase Obg [obg]. 1 330 47.763 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 326 8.5E-142 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.4E-25 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 PIRSF PIRSF002401 1 332 2.6E-140 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 SUPERFAMILY SSF52540 160 329 1.23E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 Gene3D G3DSA:3.40.50.300 158 332 8.0E-57 T 12-10-2018 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 5.0E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.0E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.0E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 5.0E-36 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 324 1.6E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 SUPERFAMILY SSF82051 1 157 1.96E-57 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily THERU_08480 c03a6a3e55dd1ff0a27a6b364c1dda41 333 Gene3D G3DSA:2.70.210.12 1 157 4.7E-61 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily THERU_01935 994082196158527e5b4ffb7369313487 245 SUPERFAMILY SSF52172 2 126 2.28E-27 T 12-10-2018 IPR011006 CheY-like superfamily THERU_01935 994082196158527e5b4ffb7369313487 245 Gene3D G3DSA:2.40.50.40 137 205 9.3E-15 T 12-10-2018 THERU_01935 994082196158527e5b4ffb7369313487 245 Pfam PF04397 LytTr DNA-binding domain 147 243 5.7E-25 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THERU_01935 994082196158527e5b4ffb7369313487 245 SMART SM00448 1 113 1.9E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_01935 994082196158527e5b4ffb7369313487 245 Pfam PF00072 Response regulator receiver domain 4 113 2.2E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_01935 994082196158527e5b4ffb7369313487 245 Gene3D G3DSA:3.40.50.2300 1 127 2.4E-30 T 12-10-2018 THERU_01935 994082196158527e5b4ffb7369313487 245 SMART SM00850 146 244 1.1E-27 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THERU_07435 5d6f5ad21c6b62b9706f193e4308c4d4 288 Pfam PF00589 Phage integrase family 113 274 2.1E-18 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THERU_07435 5d6f5ad21c6b62b9706f193e4308c4d4 288 Gene3D G3DSA:1.10.443.10 105 287 4.3E-28 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THERU_07435 5d6f5ad21c6b62b9706f193e4308c4d4 288 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 81 1.8E-8 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THERU_07435 5d6f5ad21c6b62b9706f193e4308c4d4 288 Gene3D G3DSA:1.10.150.130 1 89 2.6E-10 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal THERU_07435 5d6f5ad21c6b62b9706f193e4308c4d4 288 SUPERFAMILY SSF56349 2 280 2.94E-36 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 PIRSF PIRSF004761 1 116 1.4E-33 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 114 5.6E-28 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 1.7E-28 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 12-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 Gene3D G3DSA:3.30.2320.80 1 115 3.1E-32 T 12-10-2018 THERU_04880 cb1d64ec84d7d2ab239a6b03f36d0df8 118 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 21.476 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THERU_08120 915c6be625e1f4a70cd58ab5257b6c23 267 Hamap MF_00443 Thiazole synthase [thiG]. 12 265 43.67 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THERU_08120 915c6be625e1f4a70cd58ab5257b6c23 267 Gene3D G3DSA:3.20.20.70 6 264 5.0E-114 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_08120 915c6be625e1f4a70cd58ab5257b6c23 267 Pfam PF05690 Thiazole biosynthesis protein ThiG 14 259 1.2E-112 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THERU_08120 915c6be625e1f4a70cd58ab5257b6c23 267 SUPERFAMILY SSF110399 11 251 7.59E-86 T 12-10-2018 THERU_06005 fd4ec4fb7e17a231d2da87d8e76f917c 189 SUPERFAMILY SSF52507 3 189 4.71E-49 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THERU_06005 fd4ec4fb7e17a231d2da87d8e76f917c 189 Pfam PF02441 Flavoprotein 3 168 8.4E-27 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THERU_06005 fd4ec4fb7e17a231d2da87d8e76f917c 189 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 4 187 5.2E-63 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like THERU_06005 fd4ec4fb7e17a231d2da87d8e76f917c 189 Gene3D G3DSA:3.40.50.1950 2 189 1.0E-68 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THERU_06005 fd4ec4fb7e17a231d2da87d8e76f917c 189 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 189 33.811 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 SUPERFAMILY SSF55486 18 143 1.66E-40 T 12-10-2018 THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 143 4.2E-34 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 Gene3D G3DSA:3.40.390.30 1 144 4.8E-53 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 Pfam PF02130 Uncharacterized protein family UPF0054 19 144 3.0E-40 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 12 143 21.967 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THERU_07520 7c2067dafe84c70d0a7482f8a9de362e 144 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site THERU_04210 3898940a60332ca325b6ceeca3a7ce85 84 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 5 20 2.5E-7 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_04210 3898940a60332ca325b6ceeca3a7ce85 84 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 35 56 2.5E-7 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_04210 3898940a60332ca325b6ceeca3a7ce85 84 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 79 3.1E-25 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_04210 3898940a60332ca325b6ceeca3a7ce85 84 Gene3D G3DSA:3.40.1690.10 4 84 1.8E-29 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal THERU_04210 3898940a60332ca325b6ceeca3a7ce85 84 SUPERFAMILY SSF160544 5 82 1.27E-26 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal THERU_05530 d4561eca22e9be797f3929504eaada25 150 SUPERFAMILY SSF52833 8 141 8.75E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_05530 d4561eca22e9be797f3929504eaada25 150 Pfam PF13098 Thioredoxin-like domain 26 125 6.7E-21 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_05530 d4561eca22e9be797f3929504eaada25 150 Gene3D G3DSA:3.40.30.10 11 150 1.9E-33 T 12-10-2018 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 SUPERFAMILY SSF81442 16 529 1.44E-152 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 27 479 3.4E-126 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 Gene3D G3DSA:1.20.210.10 9 536 2.6E-174 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 434 455 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 342 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 141 153 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 99 123 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 384 403 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 219 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 171 189 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 18 43 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 374 2.8E-77 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00815 b80ce2d4b90ebd695900a058cf57d845 548 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05540 6c43b3dda71a3f110f518dda674d3ac7 181 Gene3D G3DSA:2.70.40.10 1 175 5.9E-61 T 12-10-2018 IPR036157 dUTPase-like superfamily THERU_05540 6c43b3dda71a3f110f518dda674d3ac7 181 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 171 2.0E-60 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 THERU_05540 6c43b3dda71a3f110f518dda674d3ac7 181 Pfam PF00692 dUTPase 67 167 7.1E-17 T 12-10-2018 IPR029054 dUTPase-like THERU_05540 6c43b3dda71a3f110f518dda674d3ac7 181 Hamap MF_00146 dCTP deaminase [dcd]. 1 171 34.554 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 THERU_05540 6c43b3dda71a3f110f518dda674d3ac7 181 SUPERFAMILY SSF51283 1 173 1.07E-53 T 12-10-2018 IPR036157 dUTPase-like superfamily THERU_00150 244ab58436ace108b5fc90edfd2e50dd 78 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 12-10-2018 IPR001455 TusA-like domain THERU_00150 244ab58436ace108b5fc90edfd2e50dd 78 SUPERFAMILY SSF64307 2 77 2.09E-29 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_00150 244ab58436ace108b5fc90edfd2e50dd 78 Gene3D G3DSA:3.30.110.40 2 78 2.2E-33 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_00150 244ab58436ace108b5fc90edfd2e50dd 78 Pfam PF01206 Sulfurtransferase TusA 8 77 1.5E-28 T 12-10-2018 IPR001455 TusA-like domain THERU_07165 aaa6aad280a981b8da57455254512793 84 Gene3D G3DSA:2.40.50.100 20 84 8.1E-31 T 12-10-2018 THERU_07165 aaa6aad280a981b8da57455254512793 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 1.7E-40 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 SUPERFAMILY SSF110324 2 81 6.63E-34 T 12-10-2018 THERU_07165 aaa6aad280a981b8da57455254512793 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.7E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.7E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.7E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07165 aaa6aad280a981b8da57455254512793 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 28.407 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 84 6.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07165 aaa6aad280a981b8da57455254512793 84 Pfam PF01016 Ribosomal L27 protein 2 80 5.0E-39 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 Pfam PF08323 Starch synthase catalytic domain 2 235 2.3E-72 T 12-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 Gene3D G3DSA:3.40.50.2000 247 459 7.2E-170 T 12-10-2018 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 Gene3D G3DSA:3.40.50.2000 3 474 7.2E-170 T 12-10-2018 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 Pfam PF00534 Glycosyl transferases group 1 283 424 1.9E-12 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 476 2.6E-159 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 SUPERFAMILY SSF53756 3 477 1.41E-115 T 12-10-2018 THERU_00955 99024f0804837af628af6ca66a9e50e2 485 Hamap MF_00484 Glycogen synthase [glgA]. 1 477 41.365 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THERU_01125 4fd54a133a023b9927f19187409e117d 219 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 12 219 35.96 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THERU_01125 4fd54a133a023b9927f19187409e117d 219 Pfam PF13394 4Fe-4S single cluster domain 33 119 5.2E-17 T 12-10-2018 THERU_01125 4fd54a133a023b9927f19187409e117d 219 Gene3D G3DSA:3.20.20.70 11 219 1.1E-45 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_01125 4fd54a133a023b9927f19187409e117d 219 PIRSF PIRSF000370 10 219 2.1E-51 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THERU_01125 4fd54a133a023b9927f19187409e117d 219 SUPERFAMILY SSF102114 32 127 7.85E-20 T 12-10-2018 THERU_01125 4fd54a133a023b9927f19187409e117d 219 Pfam PF04055 Radical SAM superfamily 36 127 8.5E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 SUPERFAMILY SSF55979 125 238 6.73E-16 T 12-10-2018 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 SMART SM00480 17 361 7.8E-97 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 240 364 2.7E-19 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 SUPERFAMILY SSF55979 1 118 2.15E-21 T 12-10-2018 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 Gene3D G3DSA:3.70.10.10 134 363 3.5E-91 T 12-10-2018 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 365 6.8E-69 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 4.8E-19 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 PIRSF PIRSF000804 1 365 1.5E-88 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 Gene3D G3DSA:3.10.150.10 1 236 3.5E-91 T 12-10-2018 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 SUPERFAMILY SSF55979 241 365 3.66E-25 T 12-10-2018 THERU_07095 bf7661bf29d43c4bfaf2ae258c2f06bc 365 Pfam PF02767 DNA polymerase III beta subunit, central domain 126 237 2.5E-16 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 THERU_02545 bd6c75768005ad1c0c3e7bede14f508b 79 SUPERFAMILY SSF54814 18 64 2.94E-7 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THERU_02545 bd6c75768005ad1c0c3e7bede14f508b 79 Pfam PF13083 KH domain 6 77 3.4E-21 T 12-10-2018 THERU_02545 bd6c75768005ad1c0c3e7bede14f508b 79 Hamap MF_00088 UPF0109 protein . 4 78 22.875 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 THERU_00470 81480f0ef5adb3e976930fa086362033 422 SUPERFAMILY SSF56954 4 420 1.57E-65 T 12-10-2018 THERU_00470 81480f0ef5adb3e976930fa086362033 422 Gene3D G3DSA:1.20.1600.10 19 421 2.0E-65 T 12-10-2018 THERU_00470 81480f0ef5adb3e976930fa086362033 422 Pfam PF02321 Outer membrane efflux protein 238 416 9.5E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_00470 81480f0ef5adb3e976930fa086362033 422 Pfam PF02321 Outer membrane efflux protein 20 215 1.2E-29 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_08390 f6135271b0e164877bfa771930fb1c6f 162 SUPERFAMILY SSF75169 31 155 1.97E-18 T 12-10-2018 IPR027396 DsrEFH-like THERU_08390 f6135271b0e164877bfa771930fb1c6f 162 Gene3D G3DSA:3.40.1260.10 29 155 5.3E-18 T 12-10-2018 IPR027396 DsrEFH-like THERU_08390 f6135271b0e164877bfa771930fb1c6f 162 Pfam PF02635 DsrE/DsrF-like family 70 153 2.0E-11 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_05330 7a80e14e0fe7ef0474ba3de06f627b6b 77 SUPERFAMILY SSF103084 2 74 7.85E-18 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 THERU_05330 7a80e14e0fe7ef0474ba3de06f627b6b 77 PIRSF PIRSF001007 1 77 3.0E-22 T 12-10-2018 IPR016281 Crossover junction endodeoxyribonuclease, RusA GO:0008821 THERU_05330 7a80e14e0fe7ef0474ba3de06f627b6b 77 Pfam PF05866 Endodeoxyribonuclease RusA 1 69 8.7E-13 T 12-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 THERU_05330 7a80e14e0fe7ef0474ba3de06f627b6b 77 Gene3D G3DSA:3.30.1330.70 1 77 3.7E-16 T 12-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 299 25.012 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 307 6.7E-85 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 312 1.1E-121 T 12-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 Gene3D G3DSA:3.100.10.20 3 80 2.1E-28 T 12-10-2018 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 Pfam PF01867 CRISPR associated protein Cas1 5 268 3.2E-76 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THERU_04465 064623f78f5f552df9dd9a8b8d8a2bed 317 Gene3D G3DSA:1.20.120.920 83 316 5.7E-68 T 12-10-2018 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 125 45.375 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 12 121 1.9E-45 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 PIRSF PIRSF027377 1 125 3.0E-53 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 SUPERFAMILY SSF55620 5 115 2.82E-30 T 12-10-2018 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 Pfam PF14489 QueF-like protein 46 122 7.2E-31 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THERU_01315 6de50494b2983c6cb9c2eacebcdeee39 125 Gene3D G3DSA:3.30.1130.10 8 124 7.2E-41 T 12-10-2018 THERU_00495 7f7b6ece4f2adfaa29fddfb3c6dfc75f 132 Pfam PF02867 Ribonucleotide reductase, barrel domain 1 115 6.8E-31 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THERU_00495 7f7b6ece4f2adfaa29fddfb3c6dfc75f 132 Gene3D G3DSA:3.20.70.20 1 132 2.5E-39 T 12-10-2018 THERU_00495 7f7b6ece4f2adfaa29fddfb3c6dfc75f 132 SUPERFAMILY SSF51998 1 130 7.02E-41 T 12-10-2018 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Pfam PF01565 FAD binding domain 46 185 2.5E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 SUPERFAMILY SSF56176 9 222 3.5E-70 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Gene3D G3DSA:3.30.465.10 103 221 1.2E-43 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Gene3D G3DSA:1.10.45.10 422 462 2.8E-13 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 461 9.8E-75 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 SUPERFAMILY SSF55103 225 462 6.21E-72 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Gene3D G3DSA:3.30.43.10 6 101 7.1E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Gene3D G3DSA:3.30.70.2740 339 421 1.8E-16 T 12-10-2018 THERU_03980 9aea22996dbf946789e0d8e516fb68b1 464 Gene3D G3DSA:3.30.70.2190 222 334 5.3E-6 T 12-10-2018 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 Gene3D G3DSA:3.40.710.10 284 464 1.5E-80 T 12-10-2018 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 Gene3D G3DSA:3.30.450.330 224 546 1.5E-80 T 12-10-2018 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 171 1.2E-11 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 Gene3D G3DSA:3.90.1310.30 51 222 2.5E-34 T 12-10-2018 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 SUPERFAMILY SSF56601 223 546 1.04E-68 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THERU_06450 7d1376deda3f4d7be17327232e19e390 568 Pfam PF00905 Penicillin binding protein transpeptidase domain 249 543 3.8E-51 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THERU_06450 7d1376deda3f4d7be17327232e19e390 568 SUPERFAMILY SSF56519 54 208 2.62E-35 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 THERU_05605 a5f56ed61809d7961a1abae1b11e4e48 260 Gene3D G3DSA:1.20.120.80 71 259 8.0E-41 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05605 a5f56ed61809d7961a1abae1b11e4e48 260 SUPERFAMILY SSF81452 10 257 2.09E-45 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05605 a5f56ed61809d7961a1abae1b11e4e48 260 Pfam PF00510 Cytochrome c oxidase subunit III 15 257 1.9E-24 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05100 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF47781 480 557 5.08E-10 T 12-10-2018 IPR010994 RuvA domain 2-like THERU_05100 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF82771 11 91 1.16E-16 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THERU_05100 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF46600 181 232 3.92E-11 T 12-10-2018 IPR036876 UVR domain superfamily THERU_05100 84481b2df4162800628d58137b182dd8 558 Pfam PF01541 GIY-YIG catalytic domain 12 86 1.7E-8 T 12-10-2018 IPR000305 GIY-YIG endonuclease THERU_05100 84481b2df4162800628d58137b182dd8 558 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 4 535 1.6E-126 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THERU_05100 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:1.10.150.20 500 557 1.0E-6 T 12-10-2018 THERU_05100 84481b2df4162800628d58137b182dd8 558 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 347 491 2.6E-44 T 12-10-2018 IPR001162 UvrC family homology region THERU_05100 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:4.10.860.10 191 233 3.7E-5 T 12-10-2018 THERU_05100 84481b2df4162800628d58137b182dd8 558 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 556 22.898 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THERU_05100 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:3.40.1440.10 1 92 9.2E-25 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THERU_05100 84481b2df4162800628d58137b182dd8 558 Pfam PF02151 UvrB/uvrC motif 194 227 5.0E-5 T 12-10-2018 IPR001943 UVR domain GO:0005515 THERU_05100 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:3.30.420.340 341 499 2.2E-46 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily THERU_05100 84481b2df4162800628d58137b182dd8 558 SMART SM00465 11 91 2.6E-18 T 12-10-2018 IPR000305 GIY-YIG endonuclease THERU_04785 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF47781 480 557 5.08E-10 T 12-10-2018 IPR010994 RuvA domain 2-like THERU_04785 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF82771 11 91 1.16E-16 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THERU_04785 84481b2df4162800628d58137b182dd8 558 SUPERFAMILY SSF46600 181 232 3.92E-11 T 12-10-2018 IPR036876 UVR domain superfamily THERU_04785 84481b2df4162800628d58137b182dd8 558 Pfam PF01541 GIY-YIG catalytic domain 12 86 1.7E-8 T 12-10-2018 IPR000305 GIY-YIG endonuclease THERU_04785 84481b2df4162800628d58137b182dd8 558 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 4 535 1.6E-126 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THERU_04785 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:1.10.150.20 500 557 1.0E-6 T 12-10-2018 THERU_04785 84481b2df4162800628d58137b182dd8 558 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 347 491 2.6E-44 T 12-10-2018 IPR001162 UvrC family homology region THERU_04785 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:4.10.860.10 191 233 3.7E-5 T 12-10-2018 THERU_04785 84481b2df4162800628d58137b182dd8 558 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 556 22.898 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THERU_04785 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:3.40.1440.10 1 92 9.2E-25 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THERU_04785 84481b2df4162800628d58137b182dd8 558 Pfam PF02151 UvrB/uvrC motif 194 227 5.0E-5 T 12-10-2018 IPR001943 UVR domain GO:0005515 THERU_04785 84481b2df4162800628d58137b182dd8 558 Gene3D G3DSA:3.30.420.340 341 499 2.2E-46 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily THERU_04785 84481b2df4162800628d58137b182dd8 558 SMART SM00465 11 91 2.6E-18 T 12-10-2018 IPR000305 GIY-YIG endonuclease THERU_07120 9eb22fe45de00fb983ff7ed636c2c996 211 SUPERFAMILY SSF56281 1 206 3.67E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_07120 9eb22fe45de00fb983ff7ed636c2c996 211 Gene3D G3DSA:3.60.15.10 1 209 1.8E-64 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_07120 9eb22fe45de00fb983ff7ed636c2c996 211 Pfam PF00753 Metallo-beta-lactamase superfamily 10 189 3.9E-29 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_07120 9eb22fe45de00fb983ff7ed636c2c996 211 SMART SM00849 12 189 4.6E-42 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 SUPERFAMILY SSF51735 5 216 1.04E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_01385 22e11544077bad0e309dbc399e433098 225 Pfam PF00106 short chain dehydrogenase 4 193 3.9E-55 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THERU_01385 22e11544077bad0e309dbc399e433098 225 Gene3D G3DSA:3.40.50.720 3 222 2.4E-66 T 12-10-2018 THERU_01385 22e11544077bad0e309dbc399e433098 225 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THERU_02420 674f1c17cd39d4f27f194002a12c69f9 178 Gene3D G3DSA:2.30.110.10 1 171 3.9E-56 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 THERU_02420 674f1c17cd39d4f27f194002a12c69f9 178 Pfam PF01613 Flavin reductase like domain 23 162 1.5E-20 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 THERU_02420 674f1c17cd39d4f27f194002a12c69f9 178 SMART SM00903 21 165 3.9E-19 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 THERU_02420 674f1c17cd39d4f27f194002a12c69f9 178 SUPERFAMILY SSF50475 3 161 1.3E-42 T 12-10-2018 THERU_03865 8b70bb3b6ac4e243066aebc4462d9162 155 Gene3D G3DSA:3.40.250.10 23 152 1.0E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily THERU_03865 8b70bb3b6ac4e243066aebc4462d9162 155 SUPERFAMILY SSF52821 35 143 2.36E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily THERU_03865 8b70bb3b6ac4e243066aebc4462d9162 155 Pfam PF00581 Rhodanese-like domain 51 143 2.0E-8 T 12-10-2018 IPR001763 Rhodanese-like domain THERU_03865 8b70bb3b6ac4e243066aebc4462d9162 155 SMART SM00450 48 148 3.8E-17 T 12-10-2018 IPR001763 Rhodanese-like domain THERU_01605 6f6319f4476e82aee54275e85a393c96 233 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 223 3.2E-71 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 Gene3D G3DSA:3.30.200.20 3 229 1.5E-94 T 12-10-2018 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 232 32.346 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 SUPERFAMILY SSF56104 1 232 5.23E-82 T 12-10-2018 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 Pfam PF01259 SAICAR synthetase 3 228 1.3E-66 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 ProSitePatterns PS01058 SAICAR synthetase signature 2. 170 178 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THERU_01605 6f6319f4476e82aee54275e85a393c96 233 Gene3D G3DSA:3.30.470.20 82 218 1.5E-94 T 12-10-2018 THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 Pfam PF01230 HIT domain 12 113 9.7E-27 T 12-10-2018 IPR001310 Histidine triad (HIT) protein THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 ProSitePatterns PS00892 HIT domain signature. 92 110 - T 12-10-2018 IPR019808 Histidine triad, conserved site THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 Gene3D G3DSA:3.30.428.10 1 119 3.6E-42 T 12-10-2018 IPR036265 HIT-like superfamily THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 PRINTS PR00332 Histidine triad family signature 99 109 2.6E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 PRINTS PR00332 Histidine triad family signature 26 44 2.6E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 PRINTS PR00332 Histidine triad family signature 5 21 2.6E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein THERU_04275 2564ed9ae569cef545aa46d590b01cd8 119 SUPERFAMILY SSF54197 1 118 2.63E-38 T 12-10-2018 IPR036265 HIT-like superfamily THERU_00700 ffbccaa011b61096b04aff7c61eaaf13 478 Gene3D G3DSA:3.40.309.10 250 442 1.9E-155 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THERU_00700 ffbccaa011b61096b04aff7c61eaaf13 478 Gene3D G3DSA:3.40.605.10 25 463 1.9E-155 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THERU_00700 ffbccaa011b61096b04aff7c61eaaf13 478 SUPERFAMILY SSF53720 3 475 6.81E-152 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THERU_00700 ffbccaa011b61096b04aff7c61eaaf13 478 Pfam PF00171 Aldehyde dehydrogenase family 18 472 1.3E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 Pfam PF01106 NifU-like domain 93 156 4.6E-20 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 SUPERFAMILY SSF117916 93 158 1.37E-17 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 95 157 3.0E-11 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 Gene3D G3DSA:2.102.10.10 169 275 6.8E-21 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 Pfam PF00355 Rieske [2Fe-2S] domain 178 259 1.6E-13 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 SUPERFAMILY SSF50022 176 273 4.06E-23 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_04950 43fb346314f4da398a632f5e9a4abb5b 275 Gene3D G3DSA:3.30.300.130 85 168 2.4E-20 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_01170 6b43a57340698c1abf419cefbffb5079 390 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 67 85 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site THERU_01170 6b43a57340698c1abf419cefbffb5079 390 SUPERFAMILY SSF50621 256 388 3.77E-33 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 Gene3D G3DSA:2.40.37.10 38 383 4.3E-98 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 282 369 5.6E-14 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 67 85 9.0E-23 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 369 382 9.0E-23 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 189 202 9.0E-23 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 272 291 9.0E-23 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 87 99 9.0E-23 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 223 240 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site THERU_01170 6b43a57340698c1abf419cefbffb5079 390 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 49 281 1.5E-55 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 SUPERFAMILY SSF51419 39 283 1.37E-62 T 12-10-2018 IPR029066 PLP-binding barrel THERU_01170 6b43a57340698c1abf419cefbffb5079 390 Gene3D G3DSA:3.20.20.10 46 284 4.3E-98 T 12-10-2018 IPR029066 PLP-binding barrel THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01182 Ornithine decarboxylase signature 336 346 8.1E-20 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01182 Ornithine decarboxylase signature 65 92 8.1E-20 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01182 Ornithine decarboxylase signature 139 161 8.1E-20 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01182 Ornithine decarboxylase signature 109 133 8.1E-20 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 THERU_01170 6b43a57340698c1abf419cefbffb5079 390 PRINTS PR01182 Ornithine decarboxylase signature 356 369 8.1E-20 T 12-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 THERU_05360 99cbdcdf1a455bb35e42a4abb997f73c 464 SUPERFAMILY SSF56935 95 464 6.87E-26 T 12-10-2018 THERU_00080 069c24215d4800385fe102f571fcbcd9 468 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 145 170 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site THERU_00080 069c24215d4800385fe102f571fcbcd9 468 Gene3D G3DSA:1.20.1730.10 16 466 2.4E-77 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily THERU_00080 069c24215d4800385fe102f571fcbcd9 468 Pfam PF00474 Sodium:solute symporter family 30 418 2.6E-36 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 Pfam PF01380 SIS domain 29 145 1.4E-6 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 6 315 2.1E-89 T 12-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 SUPERFAMILY SSF53697 35 309 7.99E-57 T 12-10-2018 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 Gene3D G3DSA:3.40.50.10490 166 316 2.6E-29 T 12-10-2018 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 167 315 3.8E-47 T 12-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 THERU_00250 a878a8685502fca2863f62fb00ab059b 317 Gene3D G3DSA:3.40.50.10490 3 155 4.7E-36 T 12-10-2018 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Gene3D G3DSA:3.40.50.1220 190 363 1.7E-71 T 12-10-2018 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Gene3D G3DSA:3.40.50.970 366 574 6.5E-74 T 12-10-2018 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 SUPERFAMILY SSF52518 371 571 2.32E-74 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 544 1.8E-52 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 569 1.8E-265 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 SUPERFAMILY SSF52467 189 365 5.07E-68 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 167 2.7E-61 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Gene3D G3DSA:3.40.50.970 1 180 5.4E-75 T 12-10-2018 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 332 1.3E-53 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THERU_02845 cf7be73de12975b6e684e4803f887bf8 584 SUPERFAMILY SSF52518 2 175 2.45E-66 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_02540 04f2ede950365918f4a822585ca539ad 106 SUPERFAMILY SSF52980 6 98 3.65E-22 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THERU_02540 04f2ede950365918f4a822585ca539ad 106 Gene3D G3DSA:3.40.1350.10 6 105 7.5E-30 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 THERU_02540 04f2ede950365918f4a822585ca539ad 106 Hamap MF_00048 UPF0102 protein YraN [yraN]. 2 106 17.799 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 THERU_02540 04f2ede950365918f4a822585ca539ad 106 Pfam PF02021 Uncharacterised protein family UPF0102 8 93 1.2E-24 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 THERU_03140 f5f156d672a64a5a952e3dfa413adc0f 263 Pfam PF05673 Protein of unknown function (DUF815) 14 250 1.3E-88 T 12-10-2018 IPR008533 Domain of unknown function DUF815 THERU_03140 f5f156d672a64a5a952e3dfa413adc0f 263 SUPERFAMILY SSF52540 29 225 6.69E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03140 f5f156d672a64a5a952e3dfa413adc0f 263 Gene3D G3DSA:3.40.50.300 32 170 7.0E-11 T 12-10-2018 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 Gene3D G3DSA:2.30.42.10 205 288 2.2E-21 T 12-10-2018 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 SMART SM00228 197 261 4.2E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 SMART SM00228 106 182 9.6E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 SUPERFAMILY SSF50156 200 270 9.61E-17 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 Pfam PF13180 PDZ domain 126 188 2.5E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 424 7.0E-117 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 Gene3D G3DSA:2.30.42.10 114 203 4.1E-18 T 12-10-2018 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 SUPERFAMILY SSF50156 91 188 3.15E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 Pfam PF02163 Peptidase family M50 7 411 1.6E-82 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 THERU_01230 1caa8cc29e1400a865442378ff055db2 429 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 206 258 9.2E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 THERU_03570 c60624ed2060379e08f803a59238c89e 114 SUPERFAMILY SSF88723 9 91 3.36E-7 T 12-10-2018 IPR029060 PIN-like domain superfamily THERU_03570 c60624ed2060379e08f803a59238c89e 114 Gene3D G3DSA:3.40.50.1010 4 98 4.7E-7 T 12-10-2018 THERU_03570 c60624ed2060379e08f803a59238c89e 114 Pfam PF01850 PIN domain 7 91 1.5E-5 T 12-10-2018 IPR002716 PIN domain THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 164 170 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 SUPERFAMILY SSF53335 4 239 6.47E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 6 252 5.9E-72 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 Gene3D G3DSA:3.40.50.150 62 256 7.1E-59 T 12-10-2018 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 255 3.8E-59 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 Gene3D G3DSA:1.10.8.10 1 61 3.1E-16 T 12-10-2018 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 256 36.277 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THERU_00265 a499cb1dcbd4c4a7c4be661f5e3a68e1 257 Pfam PF05175 Methyltransferase small domain 85 170 6.4E-10 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 THERU_05830 18636f0a36c1fdbdb0490dd8c30114d4 67 Pfam PF02597 ThiS family 14 67 2.2E-8 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THERU_05830 18636f0a36c1fdbdb0490dd8c30114d4 67 Gene3D G3DSA:3.10.20.30 1 67 5.7E-13 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_05830 18636f0a36c1fdbdb0490dd8c30114d4 67 SUPERFAMILY SSF54285 3 67 2.62E-12 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THERU_02405 710e99e35d39f0c393a2d77a230a7c7d 176 SUPERFAMILY SSF50199 26 175 5.75E-36 T 12-10-2018 THERU_02405 710e99e35d39f0c393a2d77a230a7c7d 176 ProSitePatterns PS01284 Thermonuclease family signature 2. 115 125 - T 12-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 THERU_02405 710e99e35d39f0c393a2d77a230a7c7d 176 Pfam PF00565 Staphylococcal nuclease homologue 53 173 4.8E-27 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 THERU_02405 710e99e35d39f0c393a2d77a230a7c7d 176 Gene3D G3DSA:2.40.50.90 22 175 2.4E-46 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily THERU_02405 710e99e35d39f0c393a2d77a230a7c7d 176 SMART SM00318 27 174 2.8E-38 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 THERU_03075 f744a343916cf67f222f2de173efc35e 172 PIRSF PIRSF004749 1 170 4.2E-57 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 158 9.1E-47 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 SUPERFAMILY SSF56420 2 167 1.44E-58 T 12-10-2018 IPR036821 Peptide deformylase superfamily THERU_03075 f744a343916cf67f222f2de173efc35e 172 Gene3D G3DSA:3.90.45.10 1 171 6.2E-58 T 12-10-2018 IPR036821 Peptide deformylase superfamily THERU_03075 f744a343916cf67f222f2de173efc35e 172 PRINTS PR01576 Peptide deformylase signature 123 152 1.4E-34 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 PRINTS PR01576 Peptide deformylase signature 33 62 1.4E-34 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 PRINTS PR01576 Peptide deformylase signature 92 103 1.4E-34 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 PRINTS PR01576 Peptide deformylase signature 104 122 1.4E-34 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 Hamap MF_00163 Peptide deformylase [def]. 2 165 29.715 T 12-10-2018 IPR023635 Peptide deformylase THERU_03075 f744a343916cf67f222f2de173efc35e 172 Pfam PF01327 Polypeptide deformylase 3 155 3.1E-51 T 12-10-2018 IPR023635 Peptide deformylase THERU_08435 b065e02b3425d9489f190efbe827c265 108 Gene3D G3DSA:2.40.50.140 3 108 1.9E-37 T 12-10-2018 THERU_08435 b065e02b3425d9489f190efbe827c265 108 SUPERFAMILY SSF50249 7 107 1.64E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_08435 b065e02b3425d9489f190efbe827c265 108 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 1 107 8.2E-44 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THERU_08435 b065e02b3425d9489f190efbe827c265 108 Pfam PF01588 Putative tRNA binding domain 14 105 2.0E-29 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 ProSitePatterns PS00882 Nickel-dependent hydrogenases b-type cytochrome subunit signature 1. 17 34 - T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 SUPERFAMILY SSF81342 7 226 2.12E-37 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 TIGRFAM TIGR02125 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit 10 224 4.1E-53 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 133 152 3.1E-41 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 14 37 3.1E-41 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 210 223 3.1E-41 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 179 201 3.1E-41 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 58 82 3.1E-41 T 12-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 Gene3D G3DSA:1.20.950.20 1 208 6.0E-60 T 12-10-2018 THERU_04860 921d405ae8f52f6ed4984adffd92514d 233 Pfam PF01292 Prokaryotic cytochrome b561 12 218 5.3E-31 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 Gene3D G3DSA:3.30.70.1560 136 219 6.5E-50 T 12-10-2018 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 SUPERFAMILY SSF55120 54 245 3.84E-39 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 Gene3D G3DSA:3.30.70.580 69 236 6.5E-50 T 12-10-2018 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 SUPERFAMILY SSF55174 8 64 1.04E-14 T 12-10-2018 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 SMART SM00363 8 70 2.0E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 74 232 4.4E-45 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 Gene3D G3DSA:3.10.290.10 6 65 6.6E-23 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 Pfam PF00849 RNA pseudouridylate synthase 69 201 6.8E-17 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THERU_05225 8327663fef3bc2faca265c94bd46818e 247 Pfam PF01479 S4 domain 8 51 6.0E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 SUPERFAMILY SSF46548 10 89 2.62E-14 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 Pfam PF02754 Cysteine-rich domain 166 247 4.9E-20 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 Pfam PF02754 Cysteine-rich domain 279 364 4.3E-15 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 PIRSF PIRSF000139 2 387 5.3E-79 T 12-10-2018 THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 Pfam PF13183 4Fe-4S dicluster domain 10 76 7.8E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 Gene3D G3DSA:1.10.1060.10 3 91 1.6E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_01750 e212c5d7109f60831f190880b04e8d1b 387 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 SUPERFAMILY SSF101852 167 249 4.05E-10 T 12-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 SUPERFAMILY SSF102522 2 159 8.37E-54 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 PIRSF PIRSF006779 1 250 2.6E-70 T 12-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 246 5.2E-71 T 12-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 Gene3D G3DSA:3.40.50.10790 1 158 1.7E-55 T 12-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal THERU_03230 488bfe97dbb061b8693bd07e2c5363b0 250 Gene3D G3DSA:2.40.30.90 163 248 1.0E-13 T 12-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal THERU_06485 08c62f9a885e1869970b0153f429f332 392 Gene3D G3DSA:1.20.81.30 49 163 1.2E-24 T 12-10-2018 THERU_06485 08c62f9a885e1869970b0153f429f332 392 Gene3D G3DSA:1.20.81.30 244 354 9.8E-23 T 12-10-2018 THERU_06485 08c62f9a885e1869970b0153f429f332 392 Pfam PF00482 Type II secretion system (T2SS), protein F 260 382 8.8E-21 T 12-10-2018 IPR018076 Type II secretion system F domain THERU_06485 08c62f9a885e1869970b0153f429f332 392 Pfam PF00482 Type II secretion system (T2SS), protein F 64 185 8.5E-24 T 12-10-2018 IPR018076 Type II secretion system F domain THERU_06485 08c62f9a885e1869970b0153f429f332 392 PRINTS PR00812 Bacterial general secretion pathway protein F signature 355 369 2.1E-11 T 12-10-2018 IPR003004 GspF/PilC family THERU_06485 08c62f9a885e1869970b0153f429f332 392 PRINTS PR00812 Bacterial general secretion pathway protein F signature 371 390 2.1E-11 T 12-10-2018 IPR003004 GspF/PilC family THERU_06485 08c62f9a885e1869970b0153f429f332 392 PRINTS PR00812 Bacterial general secretion pathway protein F signature 59 71 2.1E-11 T 12-10-2018 IPR003004 GspF/PilC family THERU_06485 08c62f9a885e1869970b0153f429f332 392 PRINTS PR00812 Bacterial general secretion pathway protein F signature 157 185 2.1E-11 T 12-10-2018 IPR003004 GspF/PilC family THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 380 437 4.4E-10 T 12-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 SUPERFAMILY SSF51905 165 294 1.36E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 SUPERFAMILY SSF55424 380 437 9.34E-5 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 Gene3D G3DSA:3.50.50.60 160 294 6.9E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 Gene3D G3DSA:3.50.50.60 47 365 6.9E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 47 152 4.4E-9 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_06310 eb1e0b169e7fc9bcec7164bd642a00f1 438 SUPERFAMILY SSF51905 47 370 1.88E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 SUPERFAMILY SSF100950 4 317 4.19E-109 T 12-10-2018 IPR037171 NagB/RpiA transferase-like THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 33 316 5.7E-106 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 Pfam PF01008 Initiation factor 2 subunit family 45 316 2.4E-76 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 Gene3D G3DSA:1.20.120.420 1 127 4.2E-34 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 Gene3D G3DSA:3.40.50.10470 128 317 2.2E-66 T 12-10-2018 THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 2 317 36.384 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THERU_04090 8ac6bfdeb02f7bbe1cccf72fbc505cd3 317 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 4 315 7.8E-121 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Gene3D G3DSA:3.30.300.10 2 222 2.9E-142 T 12-10-2018 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Gene3D G3DSA:3.30.300.10 97 360 2.9E-142 T 12-10-2018 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Pfam PF02772 S-adenosylmethionine synthetase, central domain 104 220 1.9E-36 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 370 49.266 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 2 95 3.3E-30 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 SUPERFAMILY SSF55973 102 221 1.37E-40 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Gene3D G3DSA:3.30.300.10 5 259 2.9E-142 T 12-10-2018 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 SUPERFAMILY SSF55973 222 369 1.96E-56 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 1 368 1.4E-157 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 222 359 2.6E-55 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 PIRSF PIRSF000497 1 371 6.1E-140 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04740 d65b6cce97477d17bad965dc1d18a0a5 375 SUPERFAMILY SSF55973 2 102 2.55E-33 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THERU_04135 e1b1900cba3a21f529607716d1571697 436 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 432 69.578 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 THERU_04135 e1b1900cba3a21f529607716d1571697 436 Pfam PF01938 TRAM domain 374 430 1.1E-7 T 12-10-2018 IPR002792 TRAM domain THERU_04135 e1b1900cba3a21f529607716d1571697 436 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 2 432 5.6E-152 T 12-10-2018 THERU_04135 e1b1900cba3a21f529607716d1571697 436 Gene3D G3DSA:3.40.50.12160 1 129 1.1E-35 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily THERU_04135 e1b1900cba3a21f529607716d1571697 436 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 8.1E-31 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THERU_04135 e1b1900cba3a21f529607716d1571697 436 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THERU_04135 e1b1900cba3a21f529607716d1571697 436 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 428 1.1E-152 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THERU_04135 e1b1900cba3a21f529607716d1571697 436 SUPERFAMILY SSF102114 126 366 9.42E-65 T 12-10-2018 THERU_04135 e1b1900cba3a21f529607716d1571697 436 SMART SM00729 146 362 4.1E-61 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_04135 e1b1900cba3a21f529607716d1571697 436 Pfam PF04055 Radical SAM superfamily 150 320 5.2E-32 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_04135 e1b1900cba3a21f529607716d1571697 436 Gene3D G3DSA:3.80.30.20 143 376 9.7E-90 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_02285 f813fa48afb722096febaa45918d03e0 279 Pfam PF00535 Glycosyl transferase family 2 5 156 1.0E-32 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THERU_02285 f813fa48afb722096febaa45918d03e0 279 SUPERFAMILY SSF53448 3 209 1.13E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_02285 f813fa48afb722096febaa45918d03e0 279 Gene3D G3DSA:3.90.550.10 1 225 1.4E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_02565 c1ce5249b42f9efe4009ca3e1f7c3efb 352 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 340 2.6E-14 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THERU_02630 c65e5332caefd935678d125015efe296 801 SUPERFAMILY SSF50692 616 799 5.65E-41 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THERU_02630 c65e5332caefd935678d125015efe296 801 Gene3D G3DSA:2.40.40.20 627 799 8.7E-64 T 12-10-2018 THERU_02630 c65e5332caefd935678d125015efe296 801 Gene3D G3DSA:3.40.228.10 1 274 1.2E-77 T 12-10-2018 THERU_02630 c65e5332caefd935678d125015efe296 801 Gene3D G3DSA:3.40.228.10 547 626 2.2E-24 T 12-10-2018 THERU_02630 c65e5332caefd935678d125015efe296 801 Pfam PF00384 Molybdopterin oxidoreductase 2 441 5.9E-29 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02630 c65e5332caefd935678d125015efe296 801 SUPERFAMILY SSF53706 1 636 1.31E-217 T 12-10-2018 THERU_02630 c65e5332caefd935678d125015efe296 801 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 798 0.0 T 12-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 THERU_02630 c65e5332caefd935678d125015efe296 801 Gene3D G3DSA:3.40.50.740 310 469 5.8E-52 T 12-10-2018 THERU_02630 c65e5332caefd935678d125015efe296 801 Pfam PF01568 Molydopterin dinucleotide binding domain 678 792 4.2E-14 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THERU_07860 7c98c992329a410e1c883799015cfa05 306 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 79 304 1.7E-73 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 THERU_07860 7c98c992329a410e1c883799015cfa05 306 Pfam PF01578 Cytochrome C assembly protein 102 301 2.5E-52 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THERU_08180 c48f5312753660a7edc81e6bc50c17ae 257 Gene3D G3DSA:3.40.830.10 1 256 4.7E-54 T 12-10-2018 THERU_08180 c48f5312753660a7edc81e6bc50c17ae 257 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 4 255 2.2E-71 T 12-10-2018 THERU_08180 c48f5312753660a7edc81e6bc50c17ae 257 Hamap MF_00055 MEMO1 family protein . 2 256 44.812 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THERU_08180 c48f5312753660a7edc81e6bc50c17ae 257 Pfam PF01875 Memo-like protein 6 252 7.4E-52 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THERU_00350 eec472b1849ba089fbec51fcd51117e6 303 SUPERFAMILY SSF53067 125 296 8.64E-42 T 12-10-2018 THERU_00350 eec472b1849ba089fbec51fcd51117e6 303 Gene3D G3DSA:3.30.420.40 1 122 2.7E-36 T 12-10-2018 THERU_00350 eec472b1849ba089fbec51fcd51117e6 303 Pfam PF02541 Ppx/GppA phosphatase family 22 298 5.0E-70 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 THERU_00350 eec472b1849ba089fbec51fcd51117e6 303 SUPERFAMILY SSF53067 2 121 8.2E-29 T 12-10-2018 THERU_00350 eec472b1849ba089fbec51fcd51117e6 303 Gene3D G3DSA:3.30.420.150 123 300 2.3E-54 T 12-10-2018 THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1 262 8.4E-60 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 263 9.0E-74 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 Gene3D G3DSA:3.30.1700.10 123 265 2.2E-43 T 12-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 Gene3D G3DSA:3.30.230.20 2 122 2.7E-31 T 12-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 SUPERFAMILY SSF54211 2 111 8.34E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03195 dd034b8960624cc594ebf9d6e6fb554e 265 SUPERFAMILY SSF54211 127 263 1.67E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 158 1.6E-17 T 12-10-2018 IPR016188 PurM-like, N-terminal domain THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 Pfam PF02769 AIR synthase related protein, C-terminal domain 170 331 1.3E-29 T 12-10-2018 IPR010918 PurM-like, C-terminal domain THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 326 3.8E-132 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 SUPERFAMILY SSF55326 4 163 1.94E-41 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 Gene3D G3DSA:3.90.650.10 165 334 2.3E-62 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 SUPERFAMILY SSF56042 165 332 4.01E-54 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 Gene3D G3DSA:3.30.1330.10 3 164 2.3E-56 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_00295 75d25217c2d21a4f20bfaec0d01a8e37 335 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 334 41.557 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_03930 766b637a5c104d0f6530ce59f0e96810 154 PIRSF PIRSF000239 1 153 6.6E-24 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THERU_03930 766b637a5c104d0f6530ce59f0e96810 154 SUPERFAMILY SSF52833 1 154 5.61E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_03930 766b637a5c104d0f6530ce59f0e96810 154 Gene3D G3DSA:3.40.30.10 3 154 3.1E-48 T 12-10-2018 THERU_03930 766b637a5c104d0f6530ce59f0e96810 154 Pfam PF00578 AhpC/TSA family 5 136 2.0E-38 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THERU_05845 5b70d928cb13acfa93c177c0cd7b03bc 129 SUPERFAMILY SSF55718 1 127 3.53E-36 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THERU_05845 5b70d928cb13acfa93c177c0cd7b03bc 129 Pfam PF02036 SCP-2 sterol transfer family 11 112 2.8E-17 T 12-10-2018 IPR003033 SCP2 sterol-binding domain THERU_05845 5b70d928cb13acfa93c177c0cd7b03bc 129 Gene3D G3DSA:3.30.1050.10 2 122 1.9E-26 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 SUPERFAMILY SSF46626 22 97 1.35E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 Pfam PF00034 Cytochrome c 20 98 2.3E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 PRINTS PR00606 Class ID cytochrome C signature 86 96 9.5E-25 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 PRINTS PR00606 Class ID cytochrome C signature 75 85 9.5E-25 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 PRINTS PR00606 Class ID cytochrome C signature 22 35 9.5E-25 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 PRINTS PR00606 Class ID cytochrome C signature 37 50 9.5E-25 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 PRINTS PR00606 Class ID cytochrome C signature 60 73 9.5E-25 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 THERU_06400 2c3da6c885292aec580ab97b2cd174ab 98 Gene3D G3DSA:1.10.760.10 18 98 8.4E-35 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_02570 168897715695526a0ae68cb0a97a673d 327 SUPERFAMILY SSF51569 3 324 5.42E-146 T 12-10-2018 THERU_02570 168897715695526a0ae68cb0a97a673d 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 320 3.7E-154 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 Gene3D G3DSA:3.20.20.70 3 323 1.8E-150 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 3.2E-59 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 PIRSF PIRSF001415 1 325 6.5E-157 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_02570 168897715695526a0ae68cb0a97a673d 327 SMART SM01004 3 322 2.0E-246 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THERU_00570 1b78ad4c1a77d2ec691768750d8668fe 94 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 18 88 1.8E-20 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THERU_00570 1b78ad4c1a77d2ec691768750d8668fe 94 Gene3D G3DSA:1.10.20.60 1 91 1.5E-27 T 12-10-2018 THERU_00570 1b78ad4c1a77d2ec691768750d8668fe 94 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 1 93 21.498 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THERU_00570 1b78ad4c1a77d2ec691768750d8668fe 94 SUPERFAMILY SSF141000 1 91 5.36E-26 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 THERU_00570 1b78ad4c1a77d2ec691768750d8668fe 94 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 93 1.9E-26 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 Gene3D G3DSA:3.90.226.10 1 313 1.8E-114 T 12-10-2018 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 311 47.525 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 1 143 3.6E-60 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 83 94 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 108 126 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 129 145 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 148 161 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 164 177 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 192 201 1.5E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 1 313 4.9E-134 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THERU_04300 5d79200ff459d00e2170b2a5595081fd 314 SUPERFAMILY SSF52096 2 311 1.57E-92 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_06320 1b6c136b9bd5a1285ca71792ffb6d047 69 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 6 64 2.3E-11 T 12-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 Pfam PF00403 Heavy-metal-associated domain 7 65 1.3E-13 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 Gene3D G3DSA:3.30.70.100 1 66 1.4E-20 T 12-10-2018 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 SUPERFAMILY SSF55008 1 67 2.49E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 PRINTS PR00944 Copper ion binding protein signature 3 15 9.8E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 PRINTS PR00944 Copper ion binding protein signature 28 41 9.8E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 PRINTS PR00944 Copper ion binding protein signature 53 66 9.8E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 THERU_06720 e55a5c9226dce8cef791ade0a83346fb 70 PRINTS PR00944 Copper ion binding protein signature 15 28 9.8E-8 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 133 1.0E-39 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 Pfam PF01668 SmpB protein 10 152 2.2E-57 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 Gene3D G3DSA:2.40.280.10 2 130 4.1E-52 T 12-10-2018 IPR023620 Small protein B THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 151 4.8E-54 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 SUPERFAMILY SSF74982 3 133 4.58E-50 T 12-10-2018 IPR023620 Small protein B THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site THERU_00765 89b22a16714373eaa7a09158b5d84a75 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 66.491 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 SUPERFAMILY SSF88697 263 351 7.46E-22 T 12-10-2018 IPR015947 PUA-like superfamily THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 Hamap MF_00456 Glutamate 5-kinase [proB]. 1 249 31.721 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 ProSitePatterns PS00902 Glutamate 5-kinase signature. 196 213 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 Gene3D G3DSA:2.30.130.10 252 352 1.5E-27 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 SMART SM00359 263 345 1.2E-21 T 12-10-2018 IPR002478 PUA domain GO:0003723 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 Pfam PF00696 Amino acid kinase family 1 223 4.2E-37 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PRINTS PR00474 Glutamate 5-kinase family signature 112 133 1.3E-44 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PRINTS PR00474 Glutamate 5-kinase family signature 72 100 1.3E-44 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PRINTS PR00474 Glutamate 5-kinase family signature 144 171 1.3E-44 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PRINTS PR00474 Glutamate 5-kinase family signature 38 52 1.3E-44 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PRINTS PR00474 Glutamate 5-kinase family signature 198 218 1.3E-44 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 TIGRFAM TIGR01027 proB: glutamate 5-kinase 1 351 3.3E-118 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 Pfam PF01472 PUA domain 263 336 1.2E-24 T 12-10-2018 IPR002478 PUA domain GO:0003723 THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 SUPERFAMILY SSF53633 1 243 1.7E-53 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 Gene3D G3DSA:3.40.1160.10 1 246 5.9E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_02665 a1cb03a6ad801017e48d517a43a00c2a 352 PIRSF PIRSF000729 1 352 1.7E-118 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 SUPERFAMILY SSF82861 79 161 9.15E-11 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 Gene3D G3DSA:3.30.70.100 232 326 2.5E-13 T 12-10-2018 THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 Pfam PF00924 Mechanosensitive ion channel 121 324 1.5E-45 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 SUPERFAMILY SSF50182 163 228 3.6E-16 T 12-10-2018 IPR010920 LSM domain superfamily THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 Gene3D G3DSA:2.30.30.60 179 228 2.8E-12 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily THERU_06185 1d1b4c4d98040e65ee878b8e99a74c53 335 SUPERFAMILY SSF82689 234 324 8.37E-11 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 511 517 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 543 562 1.4E-15 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 766 788 1.4E-15 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 789 803 1.4E-15 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 508 520 1.4E-15 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 SUPERFAMILY SSF53335 484 838 4.3E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_01215 e5e856a6d2c0b4a4f865e30dc9918b56 1040 Pfam PF01555 DNA methylase 508 821 2.2E-38 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 7.9E-15 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 7.9E-15 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 7.9E-15 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.9E-15 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF55124 717 845 1.96E-18 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:1.10.10.1100 404 457 5.9E-12 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF56014 832 934 1.11E-19 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 584 738 1.7E-35 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.90.480.20 462 822 2.0E-122 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.50.50.60 4 276 9.7E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.50.50.60 106 240 9.7E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 5.3E-20 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 5.3E-20 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 5.3E-20 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 5.3E-20 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.3E-20 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.30.413.10 832 939 1.3E-23 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.30.390.30 313 383 8.7E-9 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 878 894 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF55124 462 583 9.49E-26 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00397 Sirohaem Fe-binding site signature 878 896 5.2E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 PRINTS PR00397 Sirohaem Fe-binding site signature 834 852 5.2E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 837 915 7.4E-4 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF51905 143 298 1.42E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Gene3D G3DSA:3.30.413.10 576 752 2.0E-122 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF51905 1 189 6.48E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04650 c65cc0396a9ed12242efd5031c487120 940 SUPERFAMILY SSF56014 584 738 1.44E-36 T 12-10-2018 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 278 8.1E-60 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF04324 BFD-like [2Fe-2S] binding domain 404 452 9.7E-14 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 510 573 2.2E-17 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_04650 c65cc0396a9ed12242efd5031c487120 940 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 758 818 1.8E-15 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 Pfam PF00501 AMP-binding enzyme 90 521 1.9E-102 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 12-10-2018 IPR020845 AMP-binding, conserved site THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 Gene3D G3DSA:3.30.300.30 517 628 2.8E-29 T 12-10-2018 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 28 631 2.2E-267 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 83 1.7E-20 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 Gene3D G3DSA:3.40.50.12780 56 515 9.3E-120 T 12-10-2018 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 SUPERFAMILY SSF56801 29 620 3.14E-185 T 12-10-2018 THERU_06760 2a9a71c28a54724f0835af8fa173ca77 631 Pfam PF13193 AMP-binding enzyme C-terminal domain 530 608 4.4E-30 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THERU_01400 3e61dc0c85f66b910f1984ebf5a9380e 321 Pfam PF03170 Bacterial cellulose synthase subunit 52 165 1.3E-5 T 12-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 107 1.9E-41 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 Pfam PF00467 KOW motif 7 38 1.4E-7 T 12-10-2018 IPR005824 KOW THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 107 7.4E-29 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 Gene3D G3DSA:2.30.30.30 1 106 4.9E-41 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 101 22.608 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 SMART SM00739 4 31 2.9E-5 T 12-10-2018 IPR005824 KOW THERU_01450 19d9fb99563aac82345a2d7f3907b587 116 SUPERFAMILY SSF50104 4 105 3.37E-36 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily THERU_05690 d2048d25217a7ae9eea3940b95ff6ea2 283 Pfam PF09312 SurA N-terminal domain 58 131 8.4E-13 T 12-10-2018 IPR015391 SurA N-terminal THERU_05690 d2048d25217a7ae9eea3940b95ff6ea2 283 Gene3D G3DSA:1.10.4030.30 25 191 2.2E-21 T 12-10-2018 THERU_05690 d2048d25217a7ae9eea3940b95ff6ea2 283 SUPERFAMILY SSF109998 29 156 9.02E-20 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily THERU_03305 47a2584ba35347d74c911b2cf086bff1 237 Gene3D G3DSA:3.40.920.10 3 184 4.9E-45 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THERU_03305 47a2584ba35347d74c911b2cf086bff1 237 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 7 213 1.2E-36 T 12-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 THERU_03305 47a2584ba35347d74c911b2cf086bff1 237 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 213 6.3E-46 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THERU_03305 47a2584ba35347d74c911b2cf086bff1 237 SUPERFAMILY SSF53323 5 219 1.01E-39 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 PRINTS PR00449 Transforming protein P21 ras signature 156 178 1.3E-7 T 12-10-2018 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 PRINTS PR00449 Transforming protein P21 ras signature 56 78 1.3E-7 T 12-10-2018 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 PRINTS PR00449 Transforming protein P21 ras signature 123 136 1.3E-7 T 12-10-2018 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 PRINTS PR00449 Transforming protein P21 ras signature 3 24 1.3E-7 T 12-10-2018 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 SUPERFAMILY SSF52540 2 181 2.27E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00930 1576dec41a83c822e9d165af31a80baf 189 Gene3D G3DSA:3.40.50.300 1 184 1.4E-54 T 12-10-2018 THERU_00930 1576dec41a83c822e9d165af31a80baf 189 Pfam PF00071 Ras family 41 179 8.7E-9 T 12-10-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1 111 3.8E-20 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 1 116 18.624 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 SUPERFAMILY SSF56214 2 112 5.76E-23 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 Gene3D G3DSA:3.90.470.20 1 115 6.5E-28 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 114 1.2E-20 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 5 82 2.0E-23 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THERU_03755 04e335fbe60e3cd2e81c4182ec5fefe7 121 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 114 9.6E-21 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THERU_02310 92d900e50cdcfcc656146fdc4274e6b6 99 Gene3D G3DSA:3.30.70.120 1 99 7.8E-31 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THERU_02310 92d900e50cdcfcc656146fdc4274e6b6 99 SUPERFAMILY SSF54913 1 96 8.89E-26 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THERU_02310 92d900e50cdcfcc656146fdc4274e6b6 99 Pfam PF02641 Uncharacterized ACR, COG1993 1 95 4.8E-29 T 12-10-2018 IPR003793 Domain of unknown function DUF190 THERU_01650 c87d9195250cc1068d77c8c76d896c59 57 Pfam PF12161 HsdM N-terminal domain 6 43 2.4E-13 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THERU_01650 c87d9195250cc1068d77c8c76d896c59 57 Gene3D G3DSA:1.20.1260.30 1 56 4.5E-16 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily THERU_01650 c87d9195250cc1068d77c8c76d896c59 57 SUPERFAMILY SSF53335 4 48 1.58E-9 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_01775 c4954f7d143cba1072060e1495df74e9 134 Pfam PF01029 NusB family 6 131 1.1E-29 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THERU_01775 c4954f7d143cba1072060e1495df74e9 134 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 132 3.0E-36 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 THERU_01775 c4954f7d143cba1072060e1495df74e9 134 Gene3D G3DSA:1.10.940.10 1 134 2.7E-40 T 12-10-2018 IPR035926 NusB-like superfamily THERU_01775 c4954f7d143cba1072060e1495df74e9 134 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 2 134 16.656 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 THERU_01775 c4954f7d143cba1072060e1495df74e9 134 SUPERFAMILY SSF48013 3 131 7.85E-31 T 12-10-2018 IPR035926 NusB-like superfamily THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 146 170 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 284 308 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 221 246 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 370 395 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 403 427 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 PRINTS PR00758 Arsenical pump membrane protein signature 329 351 1.7E-85 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 Pfam PF02040 Arsenical pump membrane protein 7 428 1.1E-118 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_02375 dbed5911fbdd4fc93564ecb034cf9144 437 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 5 429 3.2E-142 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 Gene3D G3DSA:3.40.50.720 2 125 8.5E-52 T 12-10-2018 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 SUPERFAMILY SSF51735 1 124 5.32E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 SMART SM00881 4 100 6.6E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 44.108 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 PIRSF PIRSF001553 1 293 5.8E-134 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 Gene3D G3DSA:3.40.50.261 126 291 8.0E-70 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 154 183 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 4.8E-38 T 12-10-2018 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 4.8E-38 T 12-10-2018 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 4.8E-38 T 12-10-2018 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 4.8E-38 T 12-10-2018 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 Pfam PF00549 CoA-ligase 153 273 4.2E-18 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 SUPERFAMILY SSF52210 125 288 1.15E-52 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 2.6E-140 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THERU_06690 aad9d9509e7e156ba6e39b288375658e 293 Pfam PF02629 CoA binding domain 6 99 4.3E-30 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_01790 8ae70c517b2f0a7a05228796a7f148fe 518 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 354 425 1.3E-5 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_01790 8ae70c517b2f0a7a05228796a7f148fe 518 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 263 341 3.8E-15 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_00680 690d29f4c61826b06bb4181494034842 524 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 356 428 1.7E-5 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_00680 690d29f4c61826b06bb4181494034842 524 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 343 4.2E-17 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 SUPERFAMILY SSF56317 1 254 2.35E-63 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 SUPERFAMILY SSF52402 289 547 5.29E-78 T 12-10-2018 THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 4 563 29.505 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 TIGRFAM TIGR00552 nadE: NAD+ synthetase 297 543 7.1E-63 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 Pfam PF00795 Carbon-nitrogen hydrolase 6 249 3.0E-34 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 PIRSF PIRSF006630 1 563 3.3E-197 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 Pfam PF02540 NAD synthase 294 538 2.1E-83 T 12-10-2018 IPR022310 NAD/GMP synthase THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 Gene3D G3DSA:3.60.110.10 3 276 1.1E-83 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_05415 af1243f3ec5cb1aaf9db4712c1eb1f1a 563 Gene3D G3DSA:3.40.50.620 291 563 6.0E-109 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_08085 f66c9ddcf505867f720d3f58470e10a2 177 Gene3D G3DSA:1.20.1220.20 12 175 1.7E-23 T 12-10-2018 THERU_08085 f66c9ddcf505867f720d3f58470e10a2 177 Pfam PF01724 Domain of unknown function DUF29 18 171 1.2E-37 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_04315 69759597eed642a704c1516064bf37e9 263 SUPERFAMILY SSF52402 1 149 3.41E-27 T 12-10-2018 THERU_04315 69759597eed642a704c1516064bf37e9 263 Gene3D G3DSA:3.40.50.12370 3 263 1.1E-53 T 12-10-2018 THERU_04315 69759597eed642a704c1516064bf37e9 263 SUPERFAMILY SSF52402 156 263 5.86E-19 T 12-10-2018 THERU_04315 69759597eed642a704c1516064bf37e9 263 Pfam PF00582 Universal stress protein family 199 263 2.7E-8 T 12-10-2018 IPR006016 UspA THERU_04315 69759597eed642a704c1516064bf37e9 263 Pfam PF00582 Universal stress protein family 1 149 3.3E-20 T 12-10-2018 IPR006016 UspA THERU_04315 69759597eed642a704c1516064bf37e9 263 PRINTS PR01438 Universal stress protein signature 241 263 1.7E-13 T 12-10-2018 IPR006015 Universal stress protein A THERU_04315 69759597eed642a704c1516064bf37e9 263 PRINTS PR01438 Universal stress protein signature 2 20 1.7E-13 T 12-10-2018 IPR006015 Universal stress protein A THERU_04315 69759597eed642a704c1516064bf37e9 263 PRINTS PR01438 Universal stress protein signature 223 235 1.7E-13 T 12-10-2018 IPR006015 Universal stress protein A THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 Pfam PF13558 Putative exonuclease SbcCD, C subunit 857 917 1.8E-11 T 12-10-2018 THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 Pfam PF13476 AAA domain 5 259 5.1E-8 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 SUPERFAMILY SSF52540 1 263 2.93E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 Gene3D G3DSA:3.40.50.300 719 959 5.6E-28 T 12-10-2018 THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 Gene3D G3DSA:3.40.50.300 1 290 1.2E-46 T 12-10-2018 THERU_00240 0e6003af3f3c84a31c461d7ffb389d29 959 SUPERFAMILY SSF52540 708 955 6.94E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07365 02e026947053db752c6fa1aa792361a8 232 SUPERFAMILY SSF54821 109 207 1.44E-38 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07365 02e026947053db752c6fa1aa792361a8 232 Gene3D G3DSA:3.30.300.20 17 108 2.7E-28 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_07365 02e026947053db752c6fa1aa792361a8 232 ProSitePatterns PS00548 Ribosomal protein S3 signature. 164 198 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07365 02e026947053db752c6fa1aa792361a8 232 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 210 1.6E-93 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THERU_07365 02e026947053db752c6fa1aa792361a8 232 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 207 38.023 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THERU_07365 02e026947053db752c6fa1aa792361a8 232 Pfam PF00189 Ribosomal protein S3, C-terminal domain 121 203 7.0E-35 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07365 02e026947053db752c6fa1aa792361a8 232 SMART SM00322 60 126 1.3E-5 T 12-10-2018 IPR004087 K Homology domain GO:0003676 THERU_07365 02e026947053db752c6fa1aa792361a8 232 Gene3D G3DSA:3.30.1140.32 109 209 2.4E-40 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07365 02e026947053db752c6fa1aa792361a8 232 Pfam PF07650 KH domain 38 112 5.4E-13 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07365 02e026947053db752c6fa1aa792361a8 232 SUPERFAMILY SSF54814 2 107 8.63E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THERU_05420 0568a93caa26287877d5dfac638e4570 274 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 53 66 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05420 0568a93caa26287877d5dfac638e4570 274 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 264 35.278 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05420 0568a93caa26287877d5dfac638e4570 274 SUPERFAMILY SSF51366 7 258 4.8E-81 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_05420 0568a93caa26287877d5dfac638e4570 274 Pfam PF00290 Tryptophan synthase alpha chain 15 262 3.4E-80 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_05420 0568a93caa26287877d5dfac638e4570 274 Gene3D G3DSA:3.20.20.70 6 266 9.1E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05420 0568a93caa26287877d5dfac638e4570 274 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 14 261 5.5E-79 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THERU_02525 7987ab803e63ed78031741e08bd0b513 163 Gene3D G3DSA:1.20.120.1200 3 160 7.9E-30 T 12-10-2018 THERU_02525 7987ab803e63ed78031741e08bd0b513 163 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 158 7.5E-27 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_01160 ade39355b22e879983a52124ad820079 220 SUPERFAMILY SSF52540 5 184 1.14E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01160 ade39355b22e879983a52124ad820079 220 Gene3D G3DSA:3.40.50.300 8 180 1.2E-59 T 12-10-2018 THERU_01160 ade39355b22e879983a52124ad820079 220 Hamap MF_00328 Guanylate kinase [gmk]. 2 184 31.81 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THERU_01160 ade39355b22e879983a52124ad820079 220 ProSitePatterns PS00856 Guanylate kinase-like signature. 38 55 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 THERU_01160 ade39355b22e879983a52124ad820079 220 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 181 4.1E-63 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THERU_01160 ade39355b22e879983a52124ad820079 220 Gene3D G3DSA:3.30.63.10 35 94 1.2E-59 T 12-10-2018 THERU_01160 ade39355b22e879983a52124ad820079 220 Pfam PF00625 Guanylate kinase 6 180 6.9E-40 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THERU_01160 ade39355b22e879983a52124ad820079 220 SMART SM00072 3 184 3.6E-46 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 Pfam PF01765 Ribosome recycling factor 20 179 6.1E-57 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 Gene3D G3DSA:1.10.132.20 10 178 2.4E-65 T 12-10-2018 THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 SUPERFAMILY SSF55194 1 179 1.57E-62 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 179 1.5E-54 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 180 24.424 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THERU_03250 a2e2890a29cc2678c75761fc64c58011 180 Gene3D G3DSA:3.30.1360.40 31 104 2.4E-65 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Gene3D G3DSA:1.10.275.10 26 230 1.6E-179 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.5E-25 T 12-10-2018 IPR000362 Fumarate lyase family THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 2.5E-25 T 12-10-2018 IPR000362 Fumarate lyase family THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.5E-25 T 12-10-2018 IPR000362 Fumarate lyase family THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 2.5E-25 T 12-10-2018 IPR000362 Fumarate lyase family THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Pfam PF14698 Argininosuccinate lyase C-terminal 363 429 5.2E-22 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 453 41.701 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 1.3E-57 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Pfam PF00206 Lyase 7 301 4.8E-72 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Gene3D G3DSA:1.10.40.30 361 432 1.6E-179 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 SUPERFAMILY SSF48557 7 452 2.04E-132 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 454 4.3E-185 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 Gene3D G3DSA:1.20.200.10 120 446 1.6E-179 T 12-10-2018 THERU_03745 047ea0f1e6bbafb483c091e801ddf19f 457 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THERU_07565 1fee2390cb595e7192b90660f5257db9 351 SUPERFAMILY SSF53383 18 345 3.03E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_07565 1fee2390cb595e7192b90660f5257db9 351 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 347 53.938 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THERU_07565 1fee2390cb595e7192b90660f5257db9 351 Gene3D G3DSA:3.90.1150.10 6 342 1.2E-103 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_07565 1fee2390cb595e7192b90660f5257db9 351 Gene3D G3DSA:3.40.640.10 43 255 1.2E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_07565 1fee2390cb595e7192b90660f5257db9 351 Pfam PF00155 Aminotransferase class I and II 20 342 6.8E-46 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_07565 1fee2390cb595e7192b90660f5257db9 351 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 4 345 6.1E-103 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THERU_03255 db32042b930327555a6f3dc3b3f8f62a 407 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 53 190 2.0E-12 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SMART SM00874 394 463 3.2E-15 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:3.30.56.10 5 178 1.3E-52 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SUPERFAMILY SSF56037 199 384 2.25E-67 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SUPERFAMILY SSF46955 394 466 1.74E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:3.50.40.10 189 390 4.1E-77 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Pfam PF03484 tRNA synthetase B5 domain 399 463 8.7E-11 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SMART SM00873 206 378 9.9E-82 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:2.40.50.140 39 151 1.3E-52 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:3.30.70.380 668 759 6.4E-15 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 753 37.666 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:3.30.930.10 476 657 3.6E-36 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 759 3.7E-220 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Pfam PF03483 B3/4 domain 207 378 2.9E-63 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SUPERFAMILY SSF50249 35 189 3.19E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Pfam PF01588 Putative tRNA binding domain 45 142 3.4E-17 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SMART SM00896 667 759 2.6E-24 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Gene3D G3DSA:3.30.56.10 393 466 9.7E-13 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 Pfam PF03147 Ferredoxin-fold anticodon binding domain 667 759 1.2E-17 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SUPERFAMILY SSF55681 459 656 9.11E-34 T 12-10-2018 THERU_08190 02f7792dae1a86aa0ef9d3e4b32c43d4 759 SUPERFAMILY SSF54991 662 759 3.01E-19 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 6 611 1.7E-245 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Pfam PF01134 Glucose inhibited division protein A 7 403 7.8E-163 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 4 614 41.062 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Gene3D G3DSA:1.10.10.1800 464 559 2.3E-38 T 12-10-2018 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Pfam PF13932 GidA associated domain 407 607 4.6E-66 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Gene3D G3DSA:3.50.50.60 1 218 5.8E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Gene3D G3DSA:3.50.50.60 311 463 1.8E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 373 396 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 SMART SM01228 537 608 3.9E-41 T 12-10-2018 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 278 292 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 Gene3D G3DSA:1.10.150.570 561 614 1.1E-24 T 12-10-2018 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 SUPERFAMILY SSF51905 5 266 2.99E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.0E-7 T 12-10-2018 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 511 531 3.0E-7 T 12-10-2018 THERU_00085 3ab617a35440a27cf5127082bbf7f7b3 614 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 3.0E-7 T 12-10-2018 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 Pfam PF02119 Flagellar P-ring protein 24 360 8.9E-135 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 Hamap MF_00416 Flagellar P-ring protein [flgI]. 8 361 37.374 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 39 54 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 187 205 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 105 122 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 83 102 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 24 39 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 249 261 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 58 73 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 162 180 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_02445 f5d43bf992c59b601b7f461009e26409 361 PRINTS PR01010 Flagellar P-ring protein signature 122 140 2.1E-78 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THERU_08385 899a3b9ec9f9577132a29b49a533dd19 244 Gene3D G3DSA:3.10.330.20 1 56 4.1E-14 T 12-10-2018 THERU_08385 899a3b9ec9f9577132a29b49a533dd19 244 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 51 228 2.8E-18 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 THERU_08385 899a3b9ec9f9577132a29b49a533dd19 244 SUPERFAMILY SSF53335 1 242 1.79E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_08385 899a3b9ec9f9577132a29b49a533dd19 244 PIRSF PIRSF017269 1 244 5.8E-63 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 THERU_08385 899a3b9ec9f9577132a29b49a533dd19 244 Gene3D G3DSA:3.40.50.150 61 244 1.6E-49 T 12-10-2018 THERU_07715 846bebc1f3b86a4c976d288af74ab157 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 300 1.5E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_07715 846bebc1f3b86a4c976d288af74ab157 306 SUPERFAMILY SSF161098 92 288 2.49E-19 T 12-10-2018 IPR035906 MetI-like superfamily THERU_07715 846bebc1f3b86a4c976d288af74ab157 306 Gene3D G3DSA:1.10.3720.10 80 304 7.7E-23 T 12-10-2018 IPR035906 MetI-like superfamily THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 Gene3D G3DSA:3.30.420.350 130 346 1.5E-105 T 12-10-2018 THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 Gene3D G3DSA:3.30.420.40 10 353 1.5E-105 T 12-10-2018 THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 Gene3D G3DSA:3.90.870.20 373 598 5.7E-84 T 12-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 SUPERFAMILY SSF53067 1 355 1.37E-17 T 12-10-2018 THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 Pfam PF02543 Carbamoyltransferase N-terminus 3 352 6.9E-92 T 12-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 THERU_04050 031dae152abb80607cc0d1ad3b15f32b 619 Pfam PF16861 Carbamoyltransferase C-terminus 411 600 1.5E-74 T 12-10-2018 IPR031730 Carbamoyltransferase, C-terminal THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 Gene3D G3DSA:2.40.420.20 3 334 1.8E-65 T 12-10-2018 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 270 291 2.8E-6 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 30 50 2.8E-6 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 SUPERFAMILY SSF111369 11 261 7.85E-17 T 12-10-2018 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 Gene3D G3DSA:2.40.50.100 18 205 1.8E-65 T 12-10-2018 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 Gene3D G3DSA:2.40.30.170 7 281 1.8E-65 T 12-10-2018 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 8 261 2.3E-26 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 Gene3D G3DSA:1.10.287.470 52 168 1.8E-65 T 12-10-2018 THERU_03175 237aeaab40d4edb8ad3f43f4849adba3 336 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 134 335 5.1E-28 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THERU_06330 4ee48dca6c9e1bf185f769096aa4e694 212 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 160 1.2E-4 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THERU_06330 4ee48dca6c9e1bf185f769096aa4e694 212 SUPERFAMILY SSF55681 4 204 2.57E-29 T 12-10-2018 THERU_06330 4ee48dca6c9e1bf185f769096aa4e694 212 Gene3D G3DSA:3.30.930.10 3 211 5.8E-27 T 12-10-2018 THERU_05030 44c1e17eaffaab32ab8fb0d194a75d1a 343 SMART SM00950 57 329 6.5E-6 T 12-10-2018 IPR003165 Piwi domain GO:0003676 THERU_05030 44c1e17eaffaab32ab8fb0d194a75d1a 343 Pfam PF02171 Piwi domain 57 324 4.0E-19 T 12-10-2018 IPR003165 Piwi domain GO:0003676 THERU_05030 44c1e17eaffaab32ab8fb0d194a75d1a 343 SUPERFAMILY SSF53098 13 332 7.59E-41 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_05030 44c1e17eaffaab32ab8fb0d194a75d1a 343 Gene3D G3DSA:3.40.50.2300 29 121 2.9E-13 T 12-10-2018 THERU_05030 44c1e17eaffaab32ab8fb0d194a75d1a 343 Gene3D G3DSA:3.30.420.10 123 342 3.9E-30 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 Gene3D G3DSA:3.40.710.10 227 586 6.6E-96 T 12-10-2018 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 Gene3D G3DSA:3.30.1390.30 70 144 4.4E-34 T 12-10-2018 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 SUPERFAMILY SSF56601 233 581 4.43E-86 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 Pfam PF00905 Penicillin binding protein transpeptidase domain 253 578 8.6E-64 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 6 581 1.2E-181 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 SUPERFAMILY SSF56519 42 232 2.88E-41 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 Gene3D G3DSA:3.90.1310.10 51 226 4.4E-34 T 12-10-2018 THERU_01175 04db3e8e9f934f236d614fbe4e5fb8dc 590 Pfam PF03717 Penicillin-binding Protein dimerisation domain 50 217 6.5E-31 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 Pfam PF00512 His Kinase A (phospho-acceptor) domain 104 169 2.9E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 1.1E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 1.1E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 1.1E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 PRINTS PR00344 Bacterial sensor protein C-terminal signature 269 279 1.1E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 Gene3D G3DSA:3.30.565.10 174 326 1.3E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 SMART SM00387 214 326 2.7E-42 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 SUPERFAMILY SSF55874 158 324 6.94E-50 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 SUPERFAMILY SSF47384 95 170 9.22E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 SMART SM00388 104 169 3.1E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 Gene3D G3DSA:1.10.287.130 98 169 2.5E-20 T 12-10-2018 THERU_00920 44150a56bb91a1a16a9705a4beedaf81 326 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 215 324 2.8E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THERU_02940 24ae3c94e38049cbb8d6369eb0ec1042 69 Gene3D G3DSA:3.30.160.250 1 66 2.1E-25 T 12-10-2018 THERU_02940 24ae3c94e38049cbb8d6369eb0ec1042 69 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 4 53 1.4E-8 T 12-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THERU_02940 24ae3c94e38049cbb8d6369eb0ec1042 69 SUPERFAMILY SSF143100 3 64 7.32E-19 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like THERU_01530 72588564cc31203f897010fb3d477e6c 209 SMART SM00363 98 162 2.7E-23 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01530 72588564cc31203f897010fb3d477e6c 209 Pfam PF01479 S4 domain 98 145 5.0E-23 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01530 72588564cc31203f897010fb3d477e6c 209 SUPERFAMILY SSF55174 3 208 2.36E-68 T 12-10-2018 THERU_01530 72588564cc31203f897010fb3d477e6c 209 SMART SM01390 3 97 9.5E-39 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THERU_01530 72588564cc31203f897010fb3d477e6c 209 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 35.979 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THERU_01530 72588564cc31203f897010fb3d477e6c 209 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01530 72588564cc31203f897010fb3d477e6c 209 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 3.0E-85 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THERU_01530 72588564cc31203f897010fb3d477e6c 209 Gene3D G3DSA:1.10.1050.10 6 208 8.2E-80 T 12-10-2018 THERU_01530 72588564cc31203f897010fb3d477e6c 209 Gene3D G3DSA:3.10.290.10 97 193 8.2E-80 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THERU_01530 72588564cc31203f897010fb3d477e6c 209 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 3.2E-26 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THERU_01295 6791c455021c80671846370a23538156 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 7 336 46.417 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 THERU_01295 6791c455021c80671846370a23538156 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 42 336 5.4E-96 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THERU_01295 6791c455021c80671846370a23538156 339 SUPERFAMILY SSF55681 98 337 1.04E-79 T 12-10-2018 THERU_01295 6791c455021c80671846370a23538156 339 SUPERFAMILY SSF46589 13 79 1.05E-15 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THERU_01295 6791c455021c80671846370a23538156 339 Gene3D G3DSA:3.30.930.10 6 338 2.0E-119 T 12-10-2018 THERU_01295 6791c455021c80671846370a23538156 339 Pfam PF01409 tRNA synthetases class II core domain (F) 102 336 4.0E-101 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 THERU_01295 6791c455021c80671846370a23538156 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 18 86 1.1E-20 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THERU_06735 46c09ebad4bdef53a1f01f1a69fc2e4d 202 Gene3D G3DSA:3.20.20.450 71 197 8.9E-11 T 12-10-2018 IPR035919 EAL domain superfamily THERU_06735 46c09ebad4bdef53a1f01f1a69fc2e4d 202 Pfam PF00563 EAL domain 6 193 1.7E-7 T 12-10-2018 IPR001633 EAL domain THERU_06735 46c09ebad4bdef53a1f01f1a69fc2e4d 202 SUPERFAMILY SSF141868 6 193 3.01E-13 T 12-10-2018 IPR035919 EAL domain superfamily THERU_00870 de534eaa2b62a2a32c11d1258f9c0250 87 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 13 74 2.0E-17 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_00870 de534eaa2b62a2a32c11d1258f9c0250 87 Gene3D G3DSA:3.30.300.130 2 82 2.7E-29 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_00870 de534eaa2b62a2a32c11d1258f9c0250 87 Pfam PF01106 NifU-like domain 9 74 6.2E-28 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_00870 de534eaa2b62a2a32c11d1258f9c0250 87 SUPERFAMILY SSF117916 4 77 1.7E-26 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 Gene3D G3DSA:3.40.50.300 1 281 5.2E-129 T 12-10-2018 THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 Hamap MF_01227 CTP synthase [pyrG]. 2 525 52.365 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 SUPERFAMILY SSF52540 2 267 2.46E-122 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 SUPERFAMILY SSF52317 286 524 2.21E-87 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 Pfam PF06418 CTP synthase N-terminus 3 265 1.1E-125 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 Pfam PF00117 Glutamine amidotransferase class-I 299 520 1.6E-59 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 Gene3D G3DSA:3.40.50.880 282 536 2.1E-110 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_02840 1d7e3e5c95431a1a8114e5c437a33f5b 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 520 5.9E-249 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THERU_07280 221ed5216a58294b449e164f4eb813c2 241 PIRSF PIRSF002155 1 230 2.4E-75 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07280 221ed5216a58294b449e164f4eb813c2 241 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 230 2.4E-100 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THERU_07280 221ed5216a58294b449e164f4eb813c2 241 Gene3D G3DSA:3.30.190.20 20 228 2.1E-91 T 12-10-2018 THERU_07280 221ed5216a58294b449e164f4eb813c2 241 Pfam PF00687 Ribosomal protein L1p/L10e family 36 223 6.9E-56 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein THERU_07280 221ed5216a58294b449e164f4eb813c2 241 SUPERFAMILY SSF56808 5 228 1.24E-82 T 12-10-2018 IPR023674 Ribosomal protein L1-like THERU_07280 221ed5216a58294b449e164f4eb813c2 241 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 232 41.5 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THERU_07280 221ed5216a58294b449e164f4eb813c2 241 Gene3D G3DSA:3.40.50.790 70 162 2.1E-91 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich THERU_07280 221ed5216a58294b449e164f4eb813c2 241 ProSitePatterns PS01199 Ribosomal protein L1 signature. 124 142 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Gene3D G3DSA:3.30.1360.200 180 314 5.6E-60 T 12-10-2018 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Pfam PF07549 SecD/SecF GG Motif 25 43 6.9E-5 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Gene3D G3DSA:1.20.1640.10 320 492 5.7E-10 T 12-10-2018 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 247 476 2.0E-76 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_01340 58ac25e741d6dff010996d06471b97a0 494 SUPERFAMILY SSF82866 293 489 8.11E-43 T 12-10-2018 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 PRINTS PR01755 Bacterial translocase SecF protein signature 25 40 1.8E-5 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_01340 58ac25e741d6dff010996d06471b97a0 494 PRINTS PR01755 Bacterial translocase SecF protein signature 427 442 1.8E-5 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_01340 58ac25e741d6dff010996d06471b97a0 494 PRINTS PR01755 Bacterial translocase SecF protein signature 397 415 1.8E-5 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THERU_01340 58ac25e741d6dff010996d06471b97a0 494 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 29 483 5.5E-137 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Gene3D G3DSA:3.30.70.3400 125 318 5.6E-60 T 12-10-2018 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 493 39.134 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THERU_01340 58ac25e741d6dff010996d06471b97a0 494 Pfam PF02355 Protein export membrane protein 316 487 5.4E-22 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THERU_07170 6c1b3c73d1eb52ceb3d6e651e135b5ef 99 ProSitePatterns PS01169 Ribosomal protein L21 signature. 67 89 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07170 6c1b3c73d1eb52ceb3d6e651e135b5ef 99 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 96 3.3E-34 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07170 6c1b3c73d1eb52ceb3d6e651e135b5ef 99 SUPERFAMILY SSF141091 1 96 7.19E-32 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07170 6c1b3c73d1eb52ceb3d6e651e135b5ef 99 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 98 23.64 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07170 6c1b3c73d1eb52ceb3d6e651e135b5ef 99 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 97 1.1E-27 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07455 53978d007f65ca44c18287e53df926e7 264 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 97 117 3.0E-15 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_07455 53978d007f65ca44c18287e53df926e7 264 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 209 227 3.0E-15 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_07455 53978d007f65ca44c18287e53df926e7 264 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 232 252 3.0E-15 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_07455 53978d007f65ca44c18287e53df926e7 264 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 76 90 3.0E-15 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_07455 53978d007f65ca44c18287e53df926e7 264 Gene3D G3DSA:3.40.50.150 57 257 5.2E-25 T 12-10-2018 THERU_07455 53978d007f65ca44c18287e53df926e7 264 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 80 86 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THERU_07455 53978d007f65ca44c18287e53df926e7 264 SUPERFAMILY SSF53335 59 252 5.06E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07455 53978d007f65ca44c18287e53df926e7 264 Pfam PF01555 DNA methylase 206 244 3.0E-8 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THERU_04505 507af79970ef3614412414cf90111a50 126 Gene3D G3DSA:3.10.129.10 2 125 1.1E-36 T 12-10-2018 THERU_04505 507af79970ef3614412414cf90111a50 126 Pfam PF03061 Thioesterase superfamily 15 96 1.7E-14 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THERU_04505 507af79970ef3614412414cf90111a50 126 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 4 107 2.3E-26 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THERU_04505 507af79970ef3614412414cf90111a50 126 SUPERFAMILY SSF54637 2 124 1.41E-37 T 12-10-2018 IPR029069 HotDog domain superfamily THERU_04505 507af79970ef3614412414cf90111a50 126 PIRSF PIRSF003230 1 126 7.1E-30 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THERU_04755 6437170aecf28c46317e396ccd675016 463 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 451 44.541 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THERU_04755 6437170aecf28c46317e396ccd675016 463 Pfam PF00156 Phosphoribosyl transferase domain 269 381 1.0E-9 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THERU_04755 6437170aecf28c46317e396ccd675016 463 SUPERFAMILY SSF56235 2 253 3.26E-63 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_04755 6437170aecf28c46317e396ccd675016 463 SUPERFAMILY SSF53271 247 458 1.42E-69 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_04755 6437170aecf28c46317e396ccd675016 463 PIRSF PIRSF000485 1 463 1.3E-166 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THERU_04755 6437170aecf28c46317e396ccd675016 463 Gene3D G3DSA:3.60.20.10 2 452 6.8E-152 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_04755 6437170aecf28c46317e396ccd675016 463 Gene3D G3DSA:3.40.50.2020 271 435 6.8E-152 T 12-10-2018 THERU_04755 6437170aecf28c46317e396ccd675016 463 Pfam PF13537 Glutamine amidotransferase domain 84 209 9.4E-19 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THERU_04755 6437170aecf28c46317e396ccd675016 463 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 452 2.4E-154 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THERU_07340 71d3e83f4a3d3f31f7019c5b679cc34f 198 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 2 197 31.369 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07340 71d3e83f4a3d3f31f7019c5b679cc34f 198 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 6 193 1.5E-69 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07340 71d3e83f4a3d3f31f7019c5b679cc34f 198 Gene3D G3DSA:3.40.1370.10 2 198 1.3E-75 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 THERU_07340 71d3e83f4a3d3f31f7019c5b679cc34f 198 SUPERFAMILY SSF52166 5 196 1.44E-72 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 THERU_07340 71d3e83f4a3d3f31f7019c5b679cc34f 198 Pfam PF00573 Ribosomal protein L4/L1 family 6 194 1.1E-69 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 THERU_02210 86ca65dfee81094f75077115ff767a08 169 PIRSF PIRSF000239 16 153 3.2E-20 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THERU_02210 86ca65dfee81094f75077115ff767a08 169 Gene3D G3DSA:3.40.30.10 14 167 2.5E-43 T 12-10-2018 THERU_02210 86ca65dfee81094f75077115ff767a08 169 SUPERFAMILY SSF52833 19 163 8.99E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02210 86ca65dfee81094f75077115ff767a08 169 Pfam PF00578 AhpC/TSA family 24 144 4.7E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THERU_07770 0b180346b0ccea8b392aba8d8092ad9b 295 SUPERFAMILY SSF53448 3 271 1.4E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_07770 0b180346b0ccea8b392aba8d8092ad9b 295 Gene3D G3DSA:3.90.550.10 1 290 9.4E-85 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_07770 0b180346b0ccea8b392aba8d8092ad9b 295 Pfam PF00483 Nucleotidyl transferase 5 259 3.1E-27 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THERU_07770 0b180346b0ccea8b392aba8d8092ad9b 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 2 262 2.8E-116 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 THERU_04220 75f338ac9735c73cec25ae4374048542 287 SUPERFAMILY SSF53067 112 285 3.73E-43 T 12-10-2018 THERU_04220 75f338ac9735c73cec25ae4374048542 287 Pfam PF00480 ROK family 4 283 8.7E-46 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 THERU_04220 75f338ac9735c73cec25ae4374048542 287 SUPERFAMILY SSF53067 4 110 2.99E-14 T 12-10-2018 THERU_04220 75f338ac9735c73cec25ae4374048542 287 Gene3D G3DSA:3.30.420.40 4 278 1.1E-60 T 12-10-2018 THERU_04220 75f338ac9735c73cec25ae4374048542 287 Gene3D G3DSA:3.30.420.40 109 272 1.1E-60 T 12-10-2018 THERU_00875 c83f2ef0dc4aa4e5148f893305d81a0a 331 Gene3D G3DSA:3.90.1640.10 2 194 6.7E-52 T 12-10-2018 THERU_00875 c83f2ef0dc4aa4e5148f893305d81a0a 331 Pfam PF01368 DHH family 19 154 4.0E-11 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THERU_00875 c83f2ef0dc4aa4e5148f893305d81a0a 331 Pfam PF02272 DHHA1 domain 205 315 1.9E-14 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THERU_00875 c83f2ef0dc4aa4e5148f893305d81a0a 331 Gene3D G3DSA:3.10.310.30 197 321 3.0E-34 T 12-10-2018 THERU_00875 c83f2ef0dc4aa4e5148f893305d81a0a 331 SUPERFAMILY SSF64182 18 308 1.57E-61 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 SUPERFAMILY SSF47973 2 153 7.46E-56 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 160 34.075 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 Pfam PF00177 Ribosomal protein S7p/S5e 1 153 1.2E-57 T 12-10-2018 IPR023798 Ribosomal protein S7 domain THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 PIRSF PIRSF002122 5 160 1.7E-59 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 160 4.1E-65 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THERU_07315 b2b3c437fe38bbd16211f1b7dfebc978 160 Gene3D G3DSA:1.10.455.10 2 160 1.3E-57 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 Pfam PF00691 OmpA family 130 207 6.0E-15 T 12-10-2018 IPR006665 OmpA-like domain THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 SUPERFAMILY SSF103088 105 208 3.27E-19 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 PRINTS PR01021 OMPA domain signature 174 190 3.8E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 PRINTS PR01021 OMPA domain signature 130 152 3.8E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 PRINTS PR01021 OMPA domain signature 159 174 3.8E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THERU_04240 1e798689e680a4ed9066b7ca5b5d713b 228 Gene3D G3DSA:3.30.1330.60 112 221 4.6E-21 T 12-10-2018 IPR036737 OmpA-like domain superfamily THERU_00580 8f997195ff395b73e81d21b43bc14ba2 162 SUPERFAMILY SSF111126 6 159 4.08E-28 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily THERU_00580 8f997195ff395b73e81d21b43bc14ba2 162 SMART SM00989 98 160 1.7E-21 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR THERU_00580 8f997195ff395b73e81d21b43bc14ba2 162 Pfam PF02830 V4R domain 99 159 1.3E-22 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR THERU_00580 8f997195ff395b73e81d21b43bc14ba2 162 Gene3D G3DSA:3.30.1380.20 11 162 5.7E-18 T 12-10-2018 THERU_04420 0bb1fcc13c75db703f09801aa2bea98b 330 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 2 307 2.5E-9 T 12-10-2018 IPR019016 CRISPR-associated DxTHG protein THERU_04420 0bb1fcc13c75db703f09801aa2bea98b 330 SUPERFAMILY SSF160980 1 323 1.57E-27 T 12-10-2018 THERU_06100 bf0c71c2c1301293730ccb297a81038d 739 Gene3D G3DSA:2.40.170.20 172 739 3.7E-61 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THERU_06100 bf0c71c2c1301293730ccb297a81038d 739 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 142 1.1E-9 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain THERU_06100 bf0c71c2c1301293730ccb297a81038d 739 Pfam PF00593 TonB dependent receptor 254 736 1.4E-38 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THERU_06100 bf0c71c2c1301293730ccb297a81038d 739 Gene3D G3DSA:2.170.130.10 45 165 1.2E-9 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THERU_06100 bf0c71c2c1301293730ccb297a81038d 739 SUPERFAMILY SSF56935 41 739 2.32E-84 T 12-10-2018 THERU_01890 1122ad51732cfa869a77253fd2dc5265 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 2.4E-14 T 12-10-2018 IPR003849 Preprotein translocase YajC THERU_01890 1122ad51732cfa869a77253fd2dc5265 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 2.4E-14 T 12-10-2018 IPR003849 Preprotein translocase YajC THERU_01890 1122ad51732cfa869a77253fd2dc5265 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 100 1.6E-31 T 12-10-2018 IPR003849 Preprotein translocase YajC THERU_01890 1122ad51732cfa869a77253fd2dc5265 110 SMART SM01323 20 102 4.5E-39 T 12-10-2018 IPR003849 Preprotein translocase YajC THERU_01890 1122ad51732cfa869a77253fd2dc5265 110 Pfam PF02699 Preprotein translocase subunit 24 99 2.0E-29 T 12-10-2018 IPR003849 Preprotein translocase YajC THERU_03080 ab14fec637ba99b3358c9dd0441ca0ec 99 Gene3D G3DSA:3.30.1120.40 11 99 6.5E-7 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 THERU_03080 ab14fec637ba99b3358c9dd0441ca0ec 99 Pfam PF04026 SpoVG 27 94 1.5E-7 T 12-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 THERU_03080 ab14fec637ba99b3358c9dd0441ca0ec 99 SUPERFAMILY SSF160537 27 96 1.26E-9 T 12-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 THERU_03790 9d96f71a0c5b6f15321d6d4a196ca656 132 SUPERFAMILY SSF50331 1 127 6.44E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal THERU_03790 9d96f71a0c5b6f15321d6d4a196ca656 132 Gene3D G3DSA:2.40.50.100 2 127 3.1E-17 T 12-10-2018 THERU_03790 9d96f71a0c5b6f15321d6d4a196ca656 132 Gene3D G3DSA:2.40.50.100 56 120 3.1E-17 T 12-10-2018 THERU_03790 9d96f71a0c5b6f15321d6d4a196ca656 132 Pfam PF03459 TOBE domain 69 127 1.4E-8 T 12-10-2018 IPR005116 Transport-associated OB, type 1 THERU_00940 36fd4e3e97824c863415ae5bd01218f0 300 Pfam PF11845 Protein of unknown function (DUF3365) 22 209 1.4E-30 T 12-10-2018 IPR021796 Protein of unknown function DUF3365 THERU_00940 36fd4e3e97824c863415ae5bd01218f0 300 SMART SM00304 245 297 6.1E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THERU_00940 36fd4e3e97824c863415ae5bd01218f0 300 Gene3D G3DSA:1.20.1480.50 211 300 2.2E-17 T 12-10-2018 THERU_00940 36fd4e3e97824c863415ae5bd01218f0 300 Pfam PF00672 HAMP domain 245 292 1.5E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THERU_00940 36fd4e3e97824c863415ae5bd01218f0 300 SUPERFAMILY SSF158472 245 296 4.58E-11 T 12-10-2018 THERU_02180 6f6411cc395c7fe721e4180777c8e19e 282 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 2 280 7.7E-105 T 12-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related THERU_02180 6f6411cc395c7fe721e4180777c8e19e 282 Pfam PF01040 UbiA prenyltransferase family 19 263 2.9E-47 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THERU_02180 6f6411cc395c7fe721e4180777c8e19e 282 Gene3D G3DSA:1.10.357.140 9 160 1.7E-42 T 12-10-2018 THERU_02180 6f6411cc395c7fe721e4180777c8e19e 282 Gene3D G3DSA:1.20.120.1780 161 282 8.0E-37 T 12-10-2018 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 301 1.2E-55 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 SUPERFAMILY SSF52283 3 125 2.27E-32 T 12-10-2018 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 SUPERFAMILY SSF51735 99 301 1.14E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 Gene3D G3DSA:3.40.50.720 3 325 3.4E-116 T 12-10-2018 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 331 4.5E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 Gene3D G3DSA:3.40.50.720 98 301 3.4E-116 T 12-10-2018 THERU_07180 8e7aeb33101197d663c4ec9072a20b3e 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.6E-9 T 12-10-2018 THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 243 258 2.6E-9 T 12-10-2018 THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 SUPERFAMILY SSF51905 1 319 5.99E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 Gene3D G3DSA:3.50.50.60 1 331 6.3E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 Pfam PF01494 FAD binding domain 4 167 3.5E-10 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 THERU_08055 85cdf820fa8e2bd542884ca94aae3c63 351 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 278 2.8E-59 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 1.5E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 211 232 1.5E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 1.5E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 261 271 1.5E-28 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 Gene3D G3DSA:1.10.240.10 261 361 1.6E-40 T 12-10-2018 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 188 391 6.0E-58 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 SUPERFAMILY SSF52374 2 393 1.1E-90 T 12-10-2018 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 Gene3D G3DSA:3.40.50.620 160 260 6.2E-22 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 18 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 Gene3D G3DSA:3.40.50.620 1 125 1.9E-41 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 Pfam PF00579 tRNA synthetases class I (W and Y) 191 348 1.1E-38 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01025 5299ade1dfb6d6eb147bbbf132eb5071 393 Pfam PF00579 tRNA synthetases class I (W and Y) 1 112 2.1E-26 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 Gene3D G3DSA:3.40.640.10 61 283 1.9E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 Gene3D G3DSA:3.90.1150.10 24 384 1.9E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 227 251 3.2E-15 T 12-10-2018 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 91 111 3.2E-15 T 12-10-2018 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 160 184 3.2E-15 T 12-10-2018 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 134 3.2E-15 T 12-10-2018 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 196 219 3.2E-15 T 12-10-2018 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 Pfam PF00155 Aminotransferase class I and II 30 384 1.4E-74 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_07750 4835e72b387ce6f8e138db7f3c1c2514 393 SUPERFAMILY SSF53383 2 388 6.45E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 SUPERFAMILY SSF51735 1 147 8.33E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 256 3.4E-74 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 PIRSF PIRSF000193 1 257 6.6E-66 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 Gene3D G3DSA:3.40.50.720 1 154 1.6E-40 T 12-10-2018 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 256 1.0E-30 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 Gene3D G3DSA:1.10.3730.10 155 257 1.2E-30 T 12-10-2018 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 22.884 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 SUPERFAMILY SSF48179 151 257 1.7E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_03815 b80796ed8fd9420af6d30865426d9a49 257 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 90 4.4E-13 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Gene3D G3DSA:1.10.3210.10 2 191 4.0E-78 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SUPERFAMILY SSF55021 622 699 7.38E-13 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 27 695 1.7E-238 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Gene3D G3DSA:3.30.70.260 620 699 4.6E-16 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Gene3D G3DSA:3.30.460.10 193 326 2.0E-46 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Pfam PF02824 TGS domain 387 446 1.4E-24 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SMART SM00471 42 154 7.2E-12 T 12-10-2018 IPR003607 HD/PDEase domain THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Pfam PF04607 Region found in RelA / SpoT proteins 238 346 4.7E-35 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Gene3D G3DSA:3.10.20.30 380 455 9.0E-36 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SUPERFAMILY SSF81271 376 447 4.58E-26 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Pfam PF13328 HD domain 27 177 6.8E-50 T 12-10-2018 IPR003607 HD/PDEase domain THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SMART SM00954 237 347 1.6E-59 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SUPERFAMILY SSF109604 9 191 6.28E-69 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 SUPERFAMILY SSF81301 181 391 9.48E-62 T 12-10-2018 THERU_05215 79d1d69ec298f42c84ab9dd5a9388900 700 Pfam PF13291 ACT domain 619 696 7.0E-16 T 12-10-2018 IPR002912 ACT domain THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 4.6E-35 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 4.6E-35 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 4.6E-35 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 4.6E-35 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 4.6E-35 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 Gene3D G3DSA:3.30.930.10 107 425 8.8E-132 T 12-10-2018 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 Gene3D G3DSA:1.10.287.40 1 106 2.2E-32 T 12-10-2018 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 399 2.1E-45 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 SUPERFAMILY SSF46589 1 114 9.94E-32 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 43.941 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 PIRSF PIRSF001529 1 423 5.5E-190 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.7E-32 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 2.4E-177 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THERU_02425 09e6d8b5923b795905eb12dd325e9b81 426 SUPERFAMILY SSF55681 118 423 2.38E-106 T 12-10-2018 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 165 22.122 T 12-10-2018 IPR022973 Ribosomal protein L10 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 Pfam PF00466 Ribosomal protein L10 6 99 2.3E-22 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 Gene3D G3DSA:3.30.70.1730 3 176 2.4E-33 T 12-10-2018 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 SUPERFAMILY SSF160369 4 176 3.01E-46 T 12-10-2018 THERU_07285 8b645e5fb45428bfa662ea704ad3e256 178 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 175 2.0E-4 T 12-10-2018 THERU_01015 50371f5c6914fac14cbed934128b51fb 265 SUPERFAMILY SSF111331 8 264 8.24E-72 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily THERU_01015 50371f5c6914fac14cbed934128b51fb 265 Hamap MF_00361 NAD kinase [nadK]. 1 263 29.442 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THERU_01015 50371f5c6914fac14cbed934128b51fb 265 Gene3D G3DSA:3.40.50.10330 45 263 1.4E-74 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 THERU_01015 50371f5c6914fac14cbed934128b51fb 265 Gene3D G3DSA:2.60.200.30 111 240 1.4E-74 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THERU_01015 50371f5c6914fac14cbed934128b51fb 265 Pfam PF01513 ATP-NAD kinase 44 243 2.0E-49 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 5 456 3.3E-217 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 PIRSF PIRSF000167 1 455 3.6E-175 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 SUPERFAMILY SSF102114 3 444 1.24E-140 T 12-10-2018 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 SMART SM00729 51 272 4.8E-55 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 Gene3D G3DSA:1.10.10.920 364 456 7.5E-35 T 12-10-2018 THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 Gene3D G3DSA:3.80.30.20 2 363 2.8E-122 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 Pfam PF06969 HemN C-terminal domain 365 431 2.1E-12 T 12-10-2018 IPR010723 HemN, C-terminal THERU_02340 b0f63cc27a2bdac2fb2e0a95f1b06d32 456 Pfam PF04055 Radical SAM superfamily 56 227 2.9E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 Pfam PF02445 Quinolinate synthetase A protein 22 320 4.0E-120 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 Hamap MF_00568 Quinolinate synthase A [nadA]. 18 321 45.397 T 12-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 17 322 9.9E-110 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 Gene3D G3DSA:3.40.50.10800 186 277 2.1E-116 T 12-10-2018 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 Gene3D G3DSA:3.40.50.10800 102 320 2.1E-116 T 12-10-2018 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 SUPERFAMILY SSF142754 19 321 2.35E-114 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THERU_05795 9d39096e1a5975f3a50c48fc84b62f0e 322 Gene3D G3DSA:3.40.50.10800 22 302 2.1E-116 T 12-10-2018 THERU_02385 84dab292958edfd58b15f95e2aefe7bb 216 Pfam PF04402 Protein of unknown function (DUF541) 30 177 5.2E-6 T 12-10-2018 IPR007497 Protein of unknown function DUF541 THERU_02905 b800c54f572b248a1d82bdc273629f91 215 Pfam PF04474 Protein of unknown function (DUF554) 5 214 2.2E-50 T 12-10-2018 IPR007563 Protein of unknown function DUF554 THERU_08150 b7507618278d615c71ab94b34cf321b7 355 Pfam PF00557 Metallopeptidase family M24 135 338 1.2E-60 T 12-10-2018 IPR000994 Peptidase M24 THERU_08150 b7507618278d615c71ab94b34cf321b7 355 SUPERFAMILY SSF55920 80 347 2.36E-70 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like THERU_08150 b7507618278d615c71ab94b34cf321b7 355 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 126 1.6E-17 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 THERU_08150 b7507618278d615c71ab94b34cf321b7 355 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site THERU_08150 b7507618278d615c71ab94b34cf321b7 355 Gene3D G3DSA:3.90.230.10 127 355 1.4E-72 T 12-10-2018 THERU_08150 b7507618278d615c71ab94b34cf321b7 355 Gene3D G3DSA:3.40.350.10 1 126 1.6E-24 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 SUPERFAMILY SSF111337 1 334 5.62E-126 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 Gene3D G3DSA:2.40.10.240 64 160 6.8E-118 T 12-10-2018 THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 334 45.371 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 334 4.2E-127 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 Pfam PF02547 Queuosine biosynthesis protein 3 333 5.5E-129 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THERU_02040 593593fc53bd77562d6482e54f8e1ae9 334 Gene3D G3DSA:3.40.1780.10 14 333 6.8E-118 T 12-10-2018 THERU_03455 3f9a6d1602aac7139af287edf9553153 132 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 5 21 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THERU_03455 3f9a6d1602aac7139af287edf9553153 132 SUPERFAMILY SSF75620 2 130 1.07E-57 T 12-10-2018 THERU_03455 3f9a6d1602aac7139af287edf9553153 132 Pfam PF00472 RF-1 domain 2 98 9.7E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THERU_03455 3f9a6d1602aac7139af287edf9553153 132 Gene3D G3DSA:3.30.160.20 1 63 8.1E-32 T 12-10-2018 THERU_03455 3f9a6d1602aac7139af287edf9553153 132 Gene3D G3DSA:3.30.70.1660 64 126 1.3E-11 T 12-10-2018 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 ProSitePatterns PS01134 FtsZ protein signature 1. 39 73 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 SMART SM00864 8 200 7.4E-103 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 8 168 5.2E-39 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 Gene3D G3DSA:3.40.50.1440 3 215 1.4E-80 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 Gene3D G3DSA:3.30.1330.20 220 331 3.5E-26 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 PRINTS PR00423 Cell division protein FtsZ signature 121 142 1.2E-43 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 PRINTS PR00423 Cell division protein FtsZ signature 207 228 1.2E-43 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 PRINTS PR00423 Cell division protein FtsZ signature 93 113 1.2E-43 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 PRINTS PR00423 Cell division protein FtsZ signature 184 206 1.2E-43 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 SUPERFAMILY SSF52490 7 203 6.41E-69 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 5 325 5.5E-116 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 Pfam PF12327 FtsZ family, C-terminal domain 217 307 9.8E-18 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 4 346 34.451 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 SMART SM00865 202 316 8.7E-34 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 THERU_06220 60fbb5cf37f2d68c3105217ed7746a47 355 SUPERFAMILY SSF55307 202 313 2.75E-30 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 7.5E-33 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 SUPERFAMILY SSF47336 2 76 6.67E-26 T 12-10-2018 IPR036736 ACP-like superfamily THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 Gene3D G3DSA:1.10.1200.10 2 75 6.9E-30 T 12-10-2018 IPR036736 ACP-like superfamily THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 40 75 2.0E-12 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 SMART SM00823 Phosphopantetheine attachment site 4 76 8.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 Pfam PF00550 Phosphopantetheine attachment site 6 72 3.4E-19 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain THERU_06150 bd0e4d8cee9cc80b25abd8d76ed5b913 78 Hamap MF_01217 Acyl carrier protein [acpP]. 2 76 22.872 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 44 312 5.4E-98 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 Pfam PF00571 CBS domain 267 319 3.9E-11 T 12-10-2018 IPR000644 CBS domain THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 Pfam PF00571 CBS domain 199 255 1.2E-10 T 12-10-2018 IPR000644 CBS domain THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 SMART SM00116 273 321 0.0025 T 12-10-2018 IPR000644 CBS domain THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 SMART SM00116 208 256 5.7E-6 T 12-10-2018 IPR000644 CBS domain THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 Gene3D G3DSA:3.40.50.10490 2 194 2.2E-67 T 12-10-2018 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 PIRSF PIRSF004692 1 322 1.7E-133 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 Gene3D G3DSA:3.10.580.10 195 319 2.7E-45 T 12-10-2018 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 SUPERFAMILY SSF53697 9 320 2.45E-67 T 12-10-2018 THERU_07220 95a0916328643fd8250e16f10fb57dfc 323 Pfam PF01380 SIS domain 40 170 1.3E-26 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Pfam PF07196 Flagellin hook IN motif 292 354 1.2E-5 T 12-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Gene3D G3DSA:1.20.58.1830 6 547 1.3E-87 T 12-10-2018 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Gene3D G3DSA:2.30.220.10 196 319 1.3E-87 T 12-10-2018 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Pfam PF00700 Bacterial flagellin C-terminal helical region 464 547 6.0E-20 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 SUPERFAMILY SSF64518 4 548 5.36E-66 T 12-10-2018 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 PRINTS PR00207 Flagellin signature 38 55 9.8E-9 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 PRINTS PR00207 Flagellin signature 112 135 9.8E-9 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 142 2.4E-29 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Gene3D G3DSA:2.170.280.10 179 455 1.3E-87 T 12-10-2018 THERU_00740 425a1f78696a4f964537c1e59fd5b215 548 Gene3D G3DSA:1.20.1330.10 46 507 1.3E-87 T 12-10-2018 THERU_05025 6ef3b8d17013425192a9b411592e861a 531 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 341 3.2E-20 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_05025 6ef3b8d17013425192a9b411592e861a 531 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 2 74 1.7E-14 T 12-10-2018 IPR010094 Transposase (putative), N-terminal THERU_05025 6ef3b8d17013425192a9b411592e861a 531 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 355 437 1.5E-4 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Gene3D G3DSA:3.30.365.10 37 167 1.0E-16 T 12-10-2018 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 PIRSF PIRSF036389 1 703 3.5E-244 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 SUPERFAMILY SSF56003 10 231 2.06E-35 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Gene3D G3DSA:3.30.365.10 328 419 3.4E-57 T 12-10-2018 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Gene3D G3DSA:3.90.1170.50 169 267 1.4E-10 T 12-10-2018 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Gene3D G3DSA:3.30.365.10 304 528 3.4E-57 T 12-10-2018 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 SMART SM01008 198 276 5.7E-17 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 11 177 2.9E-9 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 562 651 1.0E-13 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 301 530 3.6E-35 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 Gene3D G3DSA:3.30.365.10 553 705 6.5E-35 T 12-10-2018 THERU_06990 7f67e8e3f8cf3aa21a76642f7221cc5d 705 SUPERFAMILY SSF56003 299 705 2.09E-111 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 THERU_04160 71fec7471c93d4f51d52478e6c6170d6 155 Pfam PF01475 Ferric uptake regulator family 19 138 1.6E-33 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THERU_04160 71fec7471c93d4f51d52478e6c6170d6 155 Gene3D G3DSA:3.30.1490.190 94 149 2.3E-24 T 12-10-2018 THERU_04160 71fec7471c93d4f51d52478e6c6170d6 155 Gene3D G3DSA:1.10.10.10 2 92 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_04160 71fec7471c93d4f51d52478e6c6170d6 155 SUPERFAMILY SSF46785 11 144 1.32E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_01720 e56d58cba71a2f7e7754e5f7f25f3471 405 Gene3D G3DSA:3.30.1330.30 293 405 5.4E-8 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like THERU_01720 e56d58cba71a2f7e7754e5f7f25f3471 405 SUPERFAMILY SSF55315 293 405 8.24E-11 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like THERU_01720 e56d58cba71a2f7e7754e5f7f25f3471 405 Pfam PF03465 eRF1 domain 3 294 405 1.8E-7 T 12-10-2018 IPR005142 eRF1 domain 3 THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 Pfam PF03190 Protein of unknown function, DUF255 3 164 3.4E-74 T 12-10-2018 IPR004879 Domain of unknown function DUF255 THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 SUPERFAMILY SSF48208 166 528 8.35E-58 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 Gene3D G3DSA:1.50.10.20 389 582 7.9E-9 T 12-10-2018 THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 SUPERFAMILY SSF52833 3 130 1.96E-35 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 PIRSF PIRSF006402 1 610 3.7E-224 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 THERU_05370 22fa11f5db0c829f26ec3b180c817507 648 Gene3D G3DSA:3.40.30.10 1 171 1.9E-71 T 12-10-2018 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 327 2.9E-150 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 SMART SM00859 2 118 7.6E-44 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 Gene3D G3DSA:3.30.360.10 125 309 3.1E-143 T 12-10-2018 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 PIRSF PIRSF000148 1 330 3.2E-132 T 12-10-2018 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 312 1.7E-59 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 326 38.155 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 SUPERFAMILY SSF51735 1 154 7.79E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 Gene3D G3DSA:3.40.50.720 3 323 3.1E-143 T 12-10-2018 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 117 2.5E-34 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THERU_07895 97199c861ee266fa4e0ac1eb9695a1da 330 SUPERFAMILY SSF55347 126 313 4.64E-75 T 12-10-2018 THERU_05085 6309ec08202b8dacd81eea640192e021 300 Gene3D G3DSA:1.10.8.300 194 297 6.3E-27 T 12-10-2018 THERU_05085 6309ec08202b8dacd81eea640192e021 300 Gene3D G3DSA:3.40.50.300 14 180 2.3E-44 T 12-10-2018 THERU_05085 6309ec08202b8dacd81eea640192e021 300 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 163 1.3E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THERU_05085 6309ec08202b8dacd81eea640192e021 300 PIRSF PIRSF002849 1 300 1.6E-123 T 12-10-2018 THERU_05085 6309ec08202b8dacd81eea640192e021 300 SMART SM00382 30 171 0.0015 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_05085 6309ec08202b8dacd81eea640192e021 300 SUPERFAMILY SSF52540 12 277 1.22E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 Gene3D G3DSA:3.30.830.10 22 228 2.9E-41 T 12-10-2018 THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 Pfam PF05193 Peptidase M16 inactive domain 182 351 6.1E-23 T 12-10-2018 IPR007863 Peptidase M16, C-terminal THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 Gene3D G3DSA:3.30.830.10 237 417 6.0E-36 T 12-10-2018 THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 Pfam PF00675 Insulinase (Peptidase family M16) 41 167 7.4E-13 T 12-10-2018 IPR011765 Peptidase M16, N-terminal THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 SUPERFAMILY SSF63411 245 409 1.28E-34 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THERU_01755 94bdc246948d02e3ca47f2f64b062e32 417 SUPERFAMILY SSF63411 20 226 2.07E-42 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 SMART SM00116 12 60 0.0012 T 12-10-2018 IPR000644 CBS domain THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 Gene3D G3DSA:3.30.450.20 306 410 1.4E-10 T 12-10-2018 THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 Gene3D G3DSA:3.10.580.10 8 118 3.7E-11 T 12-10-2018 THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 Pfam PF00571 CBS domain 10 59 3.1E-8 T 12-10-2018 IPR000644 CBS domain THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 SUPERFAMILY SSF54631 11 122 9.85E-15 T 12-10-2018 THERU_02270 c9aa1adbb770e45abcef3d0117a526b8 425 SUPERFAMILY SSF103190 291 420 1.49E-21 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 305 27.051 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 134 4.1E-19 T 12-10-2018 IPR016188 PurM-like, N-terminal domain THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 Gene3D G3DSA:3.30.1330.10 1 139 5.9E-38 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 SUPERFAMILY SSF56042 138 293 5.53E-39 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 Gene3D G3DSA:3.90.650.10 140 305 3.3E-55 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 SUPERFAMILY SSF55326 2 135 1.14E-31 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 PIRSF PIRSF005303 1 305 1.4E-90 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THERU_01810 d0e0e61a030bc2a32d42ef1ff64a33e8 307 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 8 305 1.0E-86 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THERU_07650 ca8aae52fdb2a17dc7d2025d4ab4a05e 480 Pfam PF01139 tRNA-splicing ligase RtcB 48 480 3.1E-151 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THERU_07650 ca8aae52fdb2a17dc7d2025d4ab4a05e 480 Gene3D G3DSA:3.90.1860.10 4 480 2.3E-179 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THERU_07650 ca8aae52fdb2a17dc7d2025d4ab4a05e 480 SUPERFAMILY SSF103365 15 480 5.75E-163 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 4 177 2.1E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 SUPERFAMILY SSF56784 1 205 2.67E-55 T 12-10-2018 IPR036412 HAD-like superfamily THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 174 7.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 Gene3D G3DSA:1.10.150.240 16 79 4.4E-61 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 93 106 8.4E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 8.4E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 124 140 8.4E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 178 2.3E-40 T 12-10-2018 THERU_00490 9ac8d7231a328ad134490ae0594e9ba0 206 Gene3D G3DSA:3.40.50.1000 4 186 4.4E-61 T 12-10-2018 IPR023214 HAD superfamily THERU_00400 d38c3211d9e4223bae76846af292ffe5 235 Pfam PF01738 Dienelactone hydrolase family 15 233 2.4E-52 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 THERU_00400 d38c3211d9e4223bae76846af292ffe5 235 Gene3D G3DSA:3.40.50.1820 1 234 2.5E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold THERU_00400 d38c3211d9e4223bae76846af292ffe5 235 SUPERFAMILY SSF53474 2 234 1.39E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Gene3D G3DSA:3.30.930.10 222 569 1.3E-135 T 12-10-2018 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PIRSF PIRSF039101 1 122 0.0049 T 12-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PIRSF PIRSF039101 112 569 6.8E-193 T 12-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Pfam PF00152 tRNA synthetases class II (D, K and N) 227 565 8.9E-85 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Pfam PF01336 OB-fold nucleic acid binding domain 132 210 5.8E-16 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Gene3D G3DSA:2.40.50.140 1 111 1.6E-6 T 12-10-2018 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 SUPERFAMILY SSF55681 226 566 1.25E-122 T 12-10-2018 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 4 568 43.004 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 124 567 6.7E-193 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 SUPERFAMILY SSF50249 3 96 8.19E-7 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 SUPERFAMILY SSF50249 123 219 1.23E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PRINTS PR00982 Lysyl-tRNA synthetase signature 263 273 1.2E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PRINTS PR00982 Lysyl-tRNA synthetase signature 279 295 1.2E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PRINTS PR00982 Lysyl-tRNA synthetase signature 326 343 1.2E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PRINTS PR00982 Lysyl-tRNA synthetase signature 308 321 1.2E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 PRINTS PR00982 Lysyl-tRNA synthetase signature 450 466 1.2E-35 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THERU_01585 62d5fb63ac3266e03489d760c8c79331 569 Gene3D G3DSA:2.40.50.140 112 221 2.6E-33 T 12-10-2018 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 SUPERFAMILY SSF53383 2 412 3.36E-189 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 54.953 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 Pfam PF00464 Serine hydroxymethyltransferase 4 380 1.4E-177 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 Gene3D G3DSA:3.40.640.10 33 283 9.0E-191 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 PIRSF PIRSF000412 1 416 7.7E-179 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THERU_02330 a77b5e8e85aeed94e99322590b0f891b 428 Gene3D G3DSA:3.90.1150.10 6 389 9.0E-191 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 SUPERFAMILY SSF52016 440 649 1.81E-56 T 12-10-2018 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 Gene3D G3DSA:3.30.499.10 271 435 2.7E-52 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 SUPERFAMILY SSF53732 4 427 6.8E-159 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 111 124 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 350 363 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 201 214 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 91 99 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 125 140 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 PRINTS PR00415 Aconitase family signature 187 200 2.2E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 650 0.0 T 12-10-2018 IPR006250 Aconitase, putative THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 ProSitePatterns PS01244 Aconitase family signature 2. 350 363 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 Pfam PF00694 Aconitase C-terminal domain 511 584 9.3E-26 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 Pfam PF00330 Aconitase family (aconitate hydratase) 9 408 3.1E-121 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 Gene3D G3DSA:3.30.499.20 5 268 4.4E-91 T 12-10-2018 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 Gene3D G3DSA:3.20.19.10 455 652 1.0E-48 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 THERU_05280 cfdac02d679b28231e93e62d4e21cede 654 ProSitePatterns PS00450 Aconitase family signature 1. 290 306 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 PIRSF PIRSF039144 1 112 8.1E-57 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 SUPERFAMILY SSF54913 1 112 9.18E-49 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THERU_07070 3333a7305a92e7bce5532013c9714e96 112 SMART SM00938 4 105 1.7E-67 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 PRINTS PR00340 P-II protein signature 83 103 1.0E-46 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 PRINTS PR00340 P-II protein signature 23 41 1.0E-46 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 PRINTS PR00340 P-II protein signature 2 17 1.0E-46 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 PRINTS PR00340 P-II protein signature 52 75 1.0E-46 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.9E-45 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_07070 3333a7305a92e7bce5532013c9714e96 112 Gene3D G3DSA:3.30.70.120 1 112 4.7E-51 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THERU_01080 065d507210c3eb777c306662b74639e8 105 SUPERFAMILY SSF89957 3 98 6.8E-30 T 12-10-2018 IPR029756 MTH1187/YkoF-like THERU_01080 065d507210c3eb777c306662b74639e8 105 Gene3D G3DSA:3.30.70.930 1 97 3.3E-33 T 12-10-2018 IPR029756 MTH1187/YkoF-like THERU_01080 065d507210c3eb777c306662b74639e8 105 Pfam PF01910 Thiamine-binding protein 5 95 5.2E-31 T 12-10-2018 IPR002767 Thiamine-binding protein THERU_01080 065d507210c3eb777c306662b74639e8 105 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 98 3.7E-26 T 12-10-2018 IPR002767 Thiamine-binding protein THERU_01185 116f304ecad4216f5cc0355e1b645842 253 Pfam PF04085 rod shape-determining protein MreC 110 249 2.0E-20 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THERU_01185 116f304ecad4216f5cc0355e1b645842 253 Gene3D G3DSA:2.40.10.350 167 237 8.4E-18 T 12-10-2018 THERU_01185 116f304ecad4216f5cc0355e1b645842 253 Gene3D G3DSA:2.40.10.340 108 248 8.4E-18 T 12-10-2018 THERU_01680 337f1841860c8783efc5dc7967bcf068 250 Gene3D G3DSA:3.60.15.10 2 231 8.5E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_01680 337f1841860c8783efc5dc7967bcf068 250 SMART SM00849 22 212 2.3E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_01680 337f1841860c8783efc5dc7967bcf068 250 SUPERFAMILY SSF56281 9 239 4.72E-31 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_01680 337f1841860c8783efc5dc7967bcf068 250 Pfam PF00753 Metallo-beta-lactamase superfamily 21 212 1.2E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_05930 9d29b3b985f6b9b93af81c03f9e49236 457 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 453 2.5E-114 T 12-10-2018 IPR031617 Putative exopolysaccharide exporter THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 265 27.332 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 SUPERFAMILY SSF54211 4 152 2.43E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 PIRSF PIRSF010376 1 274 5.3E-69 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 Gene3D G3DSA:3.30.230.10 1 153 3.3E-50 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 253 1.1E-53 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 Gene3D G3DSA:3.30.70.890 155 267 2.3E-24 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 Pfam PF00288 GHMP kinases N terminal domain 81 138 6.7E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 THERU_03095 d9d8c66cfbc653e5372695d659c5193b 296 SUPERFAMILY SSF55060 154 257 9.11E-15 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THERU_01670 14313dd943425daefd517467b46b6ed9 325 Gene3D G3DSA:3.40.50.12300 1 325 2.6E-118 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily THERU_01670 14313dd943425daefd517467b46b6ed9 325 Pfam PF01933 Uncharacterised protein family UPF0052 3 295 3.0E-102 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 THERU_01670 14313dd943425daefd517467b46b6ed9 325 Hamap MF_00973 Gluconeogenesis factor. 1 320 32.99 T 12-10-2018 IPR010119 Gluconeogenesis factor THERU_01670 14313dd943425daefd517467b46b6ed9 325 SUPERFAMILY SSF142338 1 315 3.53E-94 T 12-10-2018 THERU_01670 14313dd943425daefd517467b46b6ed9 325 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 3 317 3.6E-115 T 12-10-2018 IPR010119 Gluconeogenesis factor THERU_04155 fd15e649c3d099439d33436beec5da53 165 Pfam PF01464 Transglycosylase SLT domain 45 153 1.0E-28 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 THERU_04155 fd15e649c3d099439d33436beec5da53 165 Gene3D G3DSA:1.10.530.10 38 165 2.3E-27 T 12-10-2018 THERU_04155 fd15e649c3d099439d33436beec5da53 165 SUPERFAMILY SSF53955 40 158 2.17E-30 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily THERU_03870 ee03f870e80cb743121a91bfb4e91478 98 SUPERFAMILY SSF81301 2 98 1.61E-23 T 12-10-2018 THERU_03870 ee03f870e80cb743121a91bfb4e91478 98 Pfam PF01909 Nucleotidyltransferase domain 11 97 1.7E-14 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THERU_03870 ee03f870e80cb743121a91bfb4e91478 98 Gene3D G3DSA:3.30.460.10 2 97 1.2E-20 T 12-10-2018 THERU_05825 5d75e10c87ad6f58f1a2678f02ef4db8 304 Gene3D G3DSA:3.40.50.620 2 302 1.9E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_05825 5d75e10c87ad6f58f1a2678f02ef4db8 304 Pfam PF01171 PP-loop family 51 168 2.1E-8 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 THERU_05825 5d75e10c87ad6f58f1a2678f02ef4db8 304 PIRSF PIRSF004976 1 303 7.0E-89 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 THERU_05825 5d75e10c87ad6f58f1a2678f02ef4db8 304 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 292 1.7E-22 T 12-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 THERU_05825 5d75e10c87ad6f58f1a2678f02ef4db8 304 SUPERFAMILY SSF52402 26 242 7.5E-45 T 12-10-2018 THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 Pfam PF01597 Glycine cleavage H-protein 15 133 2.0E-45 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 13 133 4.7E-45 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 12 133 38.853 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 SUPERFAMILY SSF51230 12 134 2.92E-44 T 12-10-2018 IPR011053 Single hybrid motif THERU_02070 6ae8d46b649110bee2bf21ad63aaea9e 175 Gene3D G3DSA:2.40.50.100 7 135 1.7E-49 T 12-10-2018 THERU_02485 47ac8069ad7b7231ac402b6be104d9fd 208 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 15 192 24.639 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02485 47ac8069ad7b7231ac402b6be104d9fd 208 Gene3D G3DSA:3.30.70.3270 41 193 5.1E-21 T 12-10-2018 THERU_02485 47ac8069ad7b7231ac402b6be104d9fd 208 SUPERFAMILY SSF54862 80 169 1.0E-15 T 12-10-2018 THERU_02485 47ac8069ad7b7231ac402b6be104d9fd 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 128 139 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02485 47ac8069ad7b7231ac402b6be104d9fd 208 Pfam PF12838 4Fe-4S dicluster domain 87 141 5.8E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_04100 e7871377b3f0646b4c8988e498b6c182 214 SMART SM00858 90 152 2.4E-5 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 THERU_04100 e7871377b3f0646b4c8988e498b6c182 214 Gene3D G3DSA:2.30.30.760 155 214 8.0E-11 T 12-10-2018 THERU_04100 e7871377b3f0646b4c8988e498b6c182 214 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 89 212 4.3E-27 T 12-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal THERU_04100 e7871377b3f0646b4c8988e498b6c182 214 Pfam PF13144 Chaperone for flagella basal body P-ring formation 83 212 7.1E-24 T 12-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal THERU_04960 fab4458b4d6d337c5ed31424e7a0bbfb 113 SMART SM00989 50 111 1.5E-7 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR THERU_04960 fab4458b4d6d337c5ed31424e7a0bbfb 113 SUPERFAMILY SSF111126 7 110 5.75E-18 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily THERU_04960 fab4458b4d6d337c5ed31424e7a0bbfb 113 Pfam PF02830 V4R domain 61 110 1.7E-14 T 12-10-2018 IPR004096 4-vinyl reductase, 4VR THERU_04960 fab4458b4d6d337c5ed31424e7a0bbfb 113 Gene3D G3DSA:3.30.1380.20 51 112 4.1E-12 T 12-10-2018 THERU_08240 c3a0430e5862ef5742e10cccaba59602 214 Pfam PF08241 Methyltransferase domain 42 127 6.3E-19 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THERU_08240 c3a0430e5862ef5742e10cccaba59602 214 Gene3D G3DSA:3.40.50.150 1 213 6.0E-48 T 12-10-2018 THERU_08240 c3a0430e5862ef5742e10cccaba59602 214 SUPERFAMILY SSF53335 2 193 9.53E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07380 1056e7f50965154702af2704f844fd95 97 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.3E-35 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07380 1056e7f50965154702af2704f844fd95 97 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 6.6E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 6.6E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 6.6E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 10 78 6.0E-13 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 Pfam PF00366 Ribosomal protein S17 12 79 8.7E-34 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 SUPERFAMILY SSF50249 7 85 3.34E-36 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07380 1056e7f50965154702af2704f844fd95 97 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.91 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07380 1056e7f50965154702af2704f844fd95 97 Gene3D G3DSA:2.40.50.140 5 97 2.1E-36 T 12-10-2018 THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 213 45.61 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 205 2.5E-60 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 PIRSF PIRSF006293 1 213 1.4E-73 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 Pfam PF06508 Queuosine biosynthesis protein QueC 4 210 3.7E-69 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 Gene3D G3DSA:3.40.50.620 1 212 8.0E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_06960 16fda95c5a1e407c20d2b819d09fd161 213 SUPERFAMILY SSF52402 1 211 1.32E-54 T 12-10-2018 THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 Gene3D G3DSA:3.30.230.40 1 89 8.0E-35 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 SUPERFAMILY SSF54211 87 178 1.02E-28 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 SUPERFAMILY SSF54211 2 86 1.2E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 1.4E-54 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 192 39.046 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THERU_03010 b0ecde80b13f9ec05085c1ad55c7c4ee 192 Gene3D G3DSA:3.30.230.40 90 192 1.4E-28 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 SUPERFAMILY SSF51569 1 213 6.59E-49 T 12-10-2018 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 ProSitePatterns PS01028 Dehydroquinase class I active site. 88 117 - T 12-10-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 Gene3D G3DSA:3.20.20.70 1 219 1.4E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 217 30.124 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 3 212 1.9E-51 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THERU_03210 fccd80f127f1a4b26ad637dea0812f05 219 Pfam PF01487 Type I 3-dehydroquinase 5 212 9.0E-43 T 12-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 SMART SM00487 226 446 0.0091 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 Pfam PF04851 Type III restriction enzyme, res subunit 230 416 1.4E-9 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 258 601 1.4E-41 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 197 1.3E-16 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 Gene3D G3DSA:3.40.50.300 220 436 2.2E-12 T 12-10-2018 THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 SMART SM00490 483 562 4.9E-9 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 Gene3D G3DSA:3.40.50.300 441 594 1.5E-17 T 12-10-2018 THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 Gene3D G3DSA:1.10.3210.30 3 169 3.1E-19 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 SUPERFAMILY SSF52540 250 570 4.03E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05040 0d5e33494bf08a03735a18be1dc76ab3 752 Pfam PF00271 Helicase conserved C-terminal domain 465 562 5.5E-11 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_02305 7ca9fe42e74aec5bb45740ce4a86d7fe 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 122 19.975 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THERU_02305 7ca9fe42e74aec5bb45740ce4a86d7fe 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 117 4.6E-25 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THERU_02305 7ca9fe42e74aec5bb45740ce4a86d7fe 124 TIGRFAM TIGR00494 crcB: protein CrcB 5 118 6.5E-30 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 SUPERFAMILY SSF56784 3 246 7.58E-53 T 12-10-2018 IPR036412 HAD-like superfamily THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 TIGRFAM TIGR01458 HAD-SF-IIA-hyp3: HAD hydrolase, TIGR01458 family 3 245 1.8E-66 T 12-10-2018 IPR006355 HAD hydrolase, LHPP/HDHD2 THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 Gene3D G3DSA:3.40.50.1000 74 177 5.3E-76 T 12-10-2018 IPR023214 HAD superfamily THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 Pfam PF13242 HAD-hyrolase-like 172 245 5.8E-20 T 12-10-2018 THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 98 3.0E-16 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 222 3.8E-36 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THERU_07050 a2ecaa5e5d0478e56b325455839401c1 253 Gene3D G3DSA:3.40.50.1000 4 243 5.3E-76 T 12-10-2018 IPR023214 HAD superfamily THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 236 9.6E-92 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 SUPERFAMILY SSF53790 1 237 3.01E-72 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 Gene3D G3DSA:3.30.950.10 118 247 2.0E-38 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.2E-48 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 THERU_04975 3becb12ed5c98163eaee440bd5baf2e2 248 Gene3D G3DSA:3.40.1010.10 1 117 3.0E-45 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 THERU_00235 ab28b63d54c2234020c2b23e20bafd06 384 Pfam PF00149 Calcineurin-like phosphoesterase 2 98 3.8E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THERU_00235 ab28b63d54c2234020c2b23e20bafd06 384 Gene3D G3DSA:3.60.21.10 1 264 5.2E-60 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like THERU_00235 ab28b63d54c2234020c2b23e20bafd06 384 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 3 245 1.4E-53 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 THERU_00235 ab28b63d54c2234020c2b23e20bafd06 384 SUPERFAMILY SSF56300 2 309 1.06E-45 T 12-10-2018 THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 Gene3D G3DSA:3.30.390.50 257 367 8.5E-17 T 12-10-2018 THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 Gene3D G3DSA:3.30.930.10 2 255 3.2E-55 T 12-10-2018 THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 573 723 8.1E-34 T 12-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 SUPERFAMILY SSF52467 580 725 1.05E-28 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 163 1.8E-4 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THERU_05680 c0dedeef3000488977a4ded429e90f2f 729 SUPERFAMILY SSF55681 1 249 7.81E-63 T 12-10-2018 THERU_05955 6e53a74ce2ab65d59696c5f1aa007ad2 348 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 158 5.0E-12 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 THERU_05955 6e53a74ce2ab65d59696c5f1aa007ad2 348 SUPERFAMILY SSF52402 5 244 5.95E-32 T 12-10-2018 THERU_05955 6e53a74ce2ab65d59696c5f1aa007ad2 348 Gene3D G3DSA:3.40.50.620 2 236 3.1E-42 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_02085 34890f259a8af881720130a335d270f4 150 Gene3D G3DSA:2.60.40.420 34 145 2.2E-32 T 12-10-2018 IPR008972 Cupredoxin THERU_02085 34890f259a8af881720130a335d270f4 150 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 90 138 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02085 34890f259a8af881720130a335d270f4 150 SUPERFAMILY SSF49503 31 145 1.79E-29 T 12-10-2018 IPR008972 Cupredoxin THERU_02085 34890f259a8af881720130a335d270f4 150 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 72 142 1.2E-12 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_03480 9e74c4e4eab72b89d473e84f2e53d797 347 SUPERFAMILY SSF53383 2 342 5.05E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_03480 9e74c4e4eab72b89d473e84f2e53d797 347 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 340 4.0E-97 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THERU_03480 9e74c4e4eab72b89d473e84f2e53d797 347 PIRSF PIRSF000390 1 346 8.5E-110 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THERU_03480 9e74c4e4eab72b89d473e84f2e53d797 347 Gene3D G3DSA:3.90.1150.10 231 345 1.7E-26 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_03480 9e74c4e4eab72b89d473e84f2e53d797 347 Gene3D G3DSA:3.40.640.10 1 229 4.1E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 1 237 57.27 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 3 229 5.4E-58 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 Gene3D G3DSA:3.20.20.70 1 240 8.2E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 ProSitePatterns PS00171 Triosephosphate isomerase active site. 162 172 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 SUPERFAMILY SSF51351 2 237 8.64E-91 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_02560 bef13fb21c8ac5c76a8ff014034115e2 241 Pfam PF00121 Triosephosphate isomerase 2 235 4.8E-87 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 210 237 1.2E-41 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 358 377 1.2E-41 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 115 135 1.2E-41 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 158 1.2E-41 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 1.2E-41 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 Gene3D G3DSA:3.40.50.300 81 243 4.0E-48 T 12-10-2018 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 ProSitePatterns PS01008 DnaA protein signature. 358 377 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 310 377 6.0E-22 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 Gene3D G3DSA:1.10.8.60 244 293 7.3E-16 T 12-10-2018 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 SUPERFAMILY SSF52540 82 288 5.7E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 SUPERFAMILY SSF48295 304 400 5.23E-25 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 SMART SM00760 308 377 1.3E-22 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 SMART SM00382 114 245 3.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 Gene3D G3DSA:1.10.1750.10 297 402 8.7E-28 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 THERU_00005 b86a6d3d2086c18b4c878a75cd24c9b5 404 Pfam PF00308 Bacterial dnaA protein 84 291 4.4E-67 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA THERU_05495 ee999c67eabf5bea77024bb51bca23bd 244 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 232 34.91 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THERU_05495 ee999c67eabf5bea77024bb51bca23bd 244 Pfam PF02348 Cytidylyltransferase 5 206 5.6E-53 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 THERU_05495 ee999c67eabf5bea77024bb51bca23bd 244 SUPERFAMILY SSF53448 1 231 1.87E-54 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_05495 ee999c67eabf5bea77024bb51bca23bd 244 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 225 3.2E-58 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THERU_05495 ee999c67eabf5bea77024bb51bca23bd 244 Gene3D G3DSA:3.90.550.10 1 232 2.2E-76 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_06525 d98e922824e15a9823f1bc05382b766b 227 SUPERFAMILY SSF53323 3 218 3.27E-43 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THERU_06525 d98e922824e15a9823f1bc05382b766b 227 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 211 9.9E-41 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THERU_06525 d98e922824e15a9823f1bc05382b766b 227 Gene3D G3DSA:3.40.920.10 1 180 4.7E-47 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THERU_06525 d98e922824e15a9823f1bc05382b766b 227 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 4 174 3.3E-35 T 12-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 THERU_00900 b5a9d538f30a031c3b0eef2aa952d1f2 48 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 13.476 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00900 b5a9d538f30a031c3b0eef2aa952d1f2 48 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 11 46 7.3E-13 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00900 b5a9d538f30a031c3b0eef2aa952d1f2 48 Pfam PF00468 Ribosomal protein L34 9 46 2.9E-16 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 Gene3D G3DSA:3.30.56.70 314 375 8.0E-24 T 12-10-2018 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 362 8.7E-100 T 12-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 2 361 3.3E-88 T 12-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 Gene3D G3DSA:3.40.50.150 1 313 8.4E-89 T 12-10-2018 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 2 368 36.204 T 12-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 THERU_08065 ba72272a30602b2599ea14e8e04db40b 378 SUPERFAMILY SSF53335 2 365 2.86E-80 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07555 d7f6be2b4b087bc1f94450d470c45c24 140 Pfam PF00892 EamA-like transporter family 2 136 3.2E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THERU_07555 d7f6be2b4b087bc1f94450d470c45c24 140 SUPERFAMILY SSF103481 47 139 3.79E-15 T 12-10-2018 THERU_06410 b17d31473938b16d8735787f258d29be 144 SUPERFAMILY SSF69500 1 143 8.24E-54 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily THERU_06410 b17d31473938b16d8735787f258d29be 144 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 7.5E-53 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THERU_06410 b17d31473938b16d8735787f258d29be 144 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 2.7E-54 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THERU_06410 b17d31473938b16d8735787f258d29be 144 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 33.764 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THERU_06410 b17d31473938b16d8735787f258d29be 144 Gene3D G3DSA:3.50.80.10 1 144 4.1E-55 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily THERU_07645 a875e0fa82d4c77c8cda4b59cc4fcc36 247 SUPERFAMILY SSF55040 3 139 5.89E-50 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_07645 a875e0fa82d4c77c8cda4b59cc4fcc36 247 Gene3D G3DSA:3.30.70.640 1 149 3.1E-52 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_07645 a875e0fa82d4c77c8cda4b59cc4fcc36 247 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 1 138 1.0E-58 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_07645 a875e0fa82d4c77c8cda4b59cc4fcc36 247 Pfam PF01967 MoaC family 4 136 8.0E-47 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 Gene3D G3DSA:1.10.10.10 124 214 4.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 SUPERFAMILY SSF46894 119 212 3.68E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 Gene3D G3DSA:3.40.50.2300 1 123 3.2E-36 T 12-10-2018 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 SMART SM00448 1 112 2.2E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 SMART SM00862 143 213 1.2E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 SUPERFAMILY SSF52172 1 122 3.84E-37 T 12-10-2018 IPR011006 CheY-like superfamily THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 212 5.8E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THERU_06060 92ef945ca939c44f57ec503b62e7c7e2 214 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THERU_07810 610019fb6fb3671ea9c8489d54160f98 357 SUPERFAMILY SSF53187 8 343 8.2E-32 T 12-10-2018 THERU_07810 610019fb6fb3671ea9c8489d54160f98 357 Pfam PF04389 Peptidase family M28 179 344 1.7E-23 T 12-10-2018 IPR007484 Peptidase M28 THERU_07810 610019fb6fb3671ea9c8489d54160f98 357 Gene3D G3DSA:3.40.630.10 132 355 6.4E-29 T 12-10-2018 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 PIRSF PIRSF001357 1 211 4.0E-64 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 Pfam PF01791 DeoC/LacD family aldolase 8 192 6.7E-10 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 Gene3D G3DSA:3.20.20.70 1 211 2.9E-74 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 SMART SM01133 2 211 1.0E-61 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 209 2.1E-63 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 211 27.783 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 THERU_03445 a12eab111dd475e742d9f19d868f4edf 211 SUPERFAMILY SSF51569 1 210 1.57E-65 T 12-10-2018 THERU_03295 155cbf05953e295231ac830d16717fc6 402 SUPERFAMILY SSF52922 278 400 6.67E-26 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_03295 155cbf05953e295231ac830d16717fc6 402 SUPERFAMILY SSF52518 30 282 1.9E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_03295 155cbf05953e295231ac830d16717fc6 402 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 44 264 3.6E-63 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THERU_03295 155cbf05953e295231ac830d16717fc6 402 Gene3D G3DSA:3.40.50.920 283 396 5.6E-25 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THERU_03295 155cbf05953e295231ac830d16717fc6 402 Gene3D G3DSA:3.40.50.970 30 282 4.3E-53 T 12-10-2018 THERU_03295 155cbf05953e295231ac830d16717fc6 402 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 288 382 1.8E-16 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II THERU_04845 58377e09476a96e3db7986d9c0354909 136 Pfam PF01402 Ribbon-helix-helix protein, copG family 8 44 1.2E-10 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THERU_04845 58377e09476a96e3db7986d9c0354909 136 Gene3D G3DSA:1.10.1220.10 12 47 4.6E-17 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THERU_04845 58377e09476a96e3db7986d9c0354909 136 Hamap MF_00476 Nickel-responsive regulator [nikR]. 5 134 28.072 T 12-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 THERU_04845 58377e09476a96e3db7986d9c0354909 136 SUPERFAMILY SSF55021 54 131 1.12E-25 T 12-10-2018 THERU_04845 58377e09476a96e3db7986d9c0354909 136 Gene3D G3DSA:3.30.70.1150 48 135 3.2E-34 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal THERU_04845 58377e09476a96e3db7986d9c0354909 136 Pfam PF08753 NikR C terminal nickel binding domain 56 130 2.3E-32 T 12-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal THERU_04845 58377e09476a96e3db7986d9c0354909 136 SUPERFAMILY SSF47598 4 51 1.06E-12 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 SUPERFAMILY SSF53098 3 130 1.52E-26 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 SMART SM00732 1 101 1.7E-17 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 Gene3D G3DSA:3.30.420.140 1 131 6.0E-31 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 131 17.611 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 Pfam PF03652 Holliday junction resolvase 2 129 4.7E-29 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THERU_02860 4017ef16f8aa4c007f6e25dd1e91874d 131 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 129 9.8E-21 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PIRSF PIRSF002133 1 124 5.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 SUPERFAMILY SSF50249 2 124 4.8E-55 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 2.6E-69 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 77 94 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 42 57 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 94 110 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 27 42 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 110 122 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 PRINTS PR01034 Ribosomal protein S12 signature 58 77 9.6E-59 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.7E-44 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 41.319 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07310 3cde6c99d00aae78d4d92ce6b9412e36 132 Gene3D G3DSA:2.40.50.140 1 132 1.4E-66 T 12-10-2018 THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 197 28.523 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 SUPERFAMILY SSF52374 3 197 2.87E-47 T 12-10-2018 THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 Pfam PF01467 Cytidylyltransferase-like 4 171 1.3E-25 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 Gene3D G3DSA:3.40.50.620 3 197 7.0E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 4.3E-11 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_07925 ec564ab7f5ce23b884814ee8d60d86df 197 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 4 196 1.3E-53 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 427 29.15 T 12-10-2018 IPR026593 Protein translocase subunit SecY THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PIRSF PIRSF004557 1 431 3.2E-132 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 SUPERFAMILY SSF103491 4 416 6.41E-119 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 423 5.1E-124 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 Gene3D G3DSA:1.10.3370.10 1 423 1.7E-159 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 ProSitePatterns PS00755 Protein secY signature 1. 71 90 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 70 90 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 396 414 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 4.5E-98 T 12-10-2018 THERU_01495 37efb4308f02aaaefd6d07097fd7a180 431 Pfam PF00344 SecY translocase 71 411 1.9E-111 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 262 2.3E-34 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 213 229 1.4E-22 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 1.4E-22 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.4E-22 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.4E-22 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 7.5E-19 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 127 7.5E-19 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 311 7.5E-19 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.5E-19 T 12-10-2018 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 SUPERFAMILY SSF51905 1 308 4.38E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 Gene3D G3DSA:3.50.50.60 2 378 2.1E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THERU_04965 a6f0cfac1449f503558ceef7b7b2c0fc 397 SUPERFAMILY SSF55424 294 390 9.28E-7 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 Pfam PF13307 Helicase C-terminal domain 492 613 6.5E-16 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 SMART SM00491 476 613 8.4E-12 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 Pfam PF00270 DEAD/DEAH box helicase 29 86 2.4E-6 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 SUPERFAMILY SSF52540 29 606 9.7E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 Gene3D G3DSA:3.40.50.300 14 249 3.9E-35 T 12-10-2018 THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 SMART SM00487 12 281 1.0E-9 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_04270 3afb98a7bc51bcb93b2e4a03a4408f8d 634 Gene3D G3DSA:3.40.50.300 456 632 8.4E-20 T 12-10-2018 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 Pfam PF13393 Histidyl-tRNA synthetase 9 308 2.2E-49 T 12-10-2018 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 Gene3D G3DSA:3.40.50.800 320 406 1.2E-26 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 400 9.9E-145 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 Pfam PF03129 Anticodon binding domain 323 406 1.5E-16 T 12-10-2018 IPR004154 Anticodon-binding THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 406 31.295 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 Gene3D G3DSA:3.30.930.10 1 318 2.4E-110 T 12-10-2018 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 PIRSF PIRSF001549 1 408 1.2E-120 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 SUPERFAMILY SSF52954 322 408 7.7E-23 T 12-10-2018 THERU_01795 40d36917a3fbc00b5829c2cca23bcd3f 409 SUPERFAMILY SSF55681 5 315 1.1E-96 T 12-10-2018 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 SUPERFAMILY SSF55205 4 428 1.14E-125 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 ProSitePatterns PS00104 EPSP synthase signature 1. 85 99 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 Gene3D G3DSA:3.65.10.10 20 231 2.3E-142 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 PIRSF PIRSF000505 1 430 6.6E-119 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 429 1.0E-136 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 Gene3D G3DSA:3.65.10.10 10 425 2.3E-142 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 429 32.6 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 425 4.5E-124 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THERU_06050 3e7f84cf4d2ca86ead12d4b08ac38aee 430 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THERU_05055 763152450b2bb7a3fdf1e64c4aa7e1be 575 TIGRFAM TIGR02556 cas_TM1802: CRISPR-associated protein, TM1802 family 23 555 1.2E-55 T 12-10-2018 IPR013389 CRISPR-associated protein Cas8b THERU_05055 763152450b2bb7a3fdf1e64c4aa7e1be 575 Pfam PF09484 CRISPR-associated protein TM1802 (cas_TM1802) 17 554 5.3E-84 T 12-10-2018 IPR013389 CRISPR-associated protein Cas8b THERU_05055 763152450b2bb7a3fdf1e64c4aa7e1be 575 TIGRFAM TIGR02591 cas_Csh1: CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI 171 553 6.9E-34 T 12-10-2018 IPR013420 CRISPR-associated protein Csh1, C-terminal THERU_07525 5930c83cfb28a4672d19e7b7cf44945b 233 Gene3D G3DSA:3.40.50.300 1 204 2.8E-78 T 12-10-2018 THERU_07525 5930c83cfb28a4672d19e7b7cf44945b 233 SUPERFAMILY SSF52540 3 181 8.87E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07525 5930c83cfb28a4672d19e7b7cf44945b 233 Pfam PF02562 PhoH-like protein 1 204 3.4E-96 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 18 93 6.3E-17 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 78 91 2.0E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 57 73 2.0E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 23 39 2.0E-11 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 1 93 15.375 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_03380 7cfc5c30d7722a33368a4bf257a00cff 93 Pfam PF02049 Flagellar hook-basal body complex protein FliE 14 93 2.0E-22 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 197 585 1.8E-150 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 311 585 1.5E-107 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Gene3D G3DSA:3.30.460.80 3 127 3.0E-31 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 SUPERFAMILY SSF56762 207 585 7.72E-124 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 181 585 45.34 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 147 2.5E-37 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Gene3D G3DSA:1.10.645.20 196 585 4.2E-153 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 80 133 2.0E-21 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 Hamap MF_01397 NADH-quinone oxidoreductase subunit C/D [nuoC]. 26 585 51.39 T 12-10-2018 IPR026662 NADH-quinone oxidoreductase subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 THERU_05455 7a97b6c190670ab0787be26c7a2dba80 585 SUPERFAMILY SSF143243 20 211 2.09E-49 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02620 95233938f980cd72b2ff57a6bb91485d 213 Pfam PF01292 Prokaryotic cytochrome b561 14 189 2.3E-28 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THERU_02620 95233938f980cd72b2ff57a6bb91485d 213 SUPERFAMILY SSF81342 12 210 2.35E-47 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THERU_02620 95233938f980cd72b2ff57a6bb91485d 213 Gene3D G3DSA:1.20.950.20 8 212 1.0E-69 T 12-10-2018 THERU_02620 95233938f980cd72b2ff57a6bb91485d 213 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 12 207 6.9E-70 T 12-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 THERU_02770 60bdabdde03a865c1357041931c5a1b4 487 SMART SM00267 305 477 1.8E-75 T 12-10-2018 IPR000160 GGDEF domain THERU_02770 60bdabdde03a865c1357041931c5a1b4 487 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 476 1.9E-57 T 12-10-2018 IPR000160 GGDEF domain THERU_02770 60bdabdde03a865c1357041931c5a1b4 487 Pfam PF00990 Diguanylate cyclase, GGDEF domain 316 473 1.3E-51 T 12-10-2018 IPR000160 GGDEF domain THERU_02770 60bdabdde03a865c1357041931c5a1b4 487 SUPERFAMILY SSF55073 321 477 2.9E-55 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_02770 60bdabdde03a865c1357041931c5a1b4 487 Gene3D G3DSA:3.30.70.270 302 478 2.9E-64 T 12-10-2018 THERU_04760 ce96cbe488b4302e72335c3fcaac2cc1 271 Gene3D G3DSA:3.20.20.70 1 259 7.0E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_04760 ce96cbe488b4302e72335c3fcaac2cc1 271 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 1 257 48.585 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THERU_04760 ce96cbe488b4302e72335c3fcaac2cc1 271 Pfam PF00793 DAHP synthetase I family 1 246 6.4E-64 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THERU_04760 ce96cbe488b4302e72335c3fcaac2cc1 271 SUPERFAMILY SSF51569 2 255 1.37E-94 T 12-10-2018 THERU_04760 ce96cbe488b4302e72335c3fcaac2cc1 271 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 1 254 2.7E-114 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THERU_01030 77e58e343c7c1260a845168d63325d96 223 Pfam PF01522 Polysaccharide deacetylase 51 185 1.2E-31 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THERU_01030 77e58e343c7c1260a845168d63325d96 223 SUPERFAMILY SSF88713 18 207 7.28E-42 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THERU_01030 77e58e343c7c1260a845168d63325d96 223 Gene3D G3DSA:3.20.20.370 1 221 2.2E-59 T 12-10-2018 THERU_01725 5356989ee43f6b406acf7807afe6cbc9 197 Gene3D G3DSA:3.40.50.1010 1 171 8.5E-46 T 12-10-2018 THERU_01725 5356989ee43f6b406acf7807afe6cbc9 197 Pfam PF01936 NYN domain 4 166 6.8E-39 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 Pfam PF00202 Aminotransferase class-III 27 441 2.5E-112 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 Gene3D G3DSA:3.90.1150.10 10 442 3.4E-162 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 PIRSF PIRSF000521 28 445 1.0E-28 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 SUPERFAMILY SSF53383 9 444 5.38E-128 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 15 442 4.4E-156 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 Gene3D G3DSA:3.40.640.10 64 340 3.4E-162 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_06110 0a451ab450d0442c118dd4aaa0e06cd6 447 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 445 52.428 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 353 1.7E-120 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 13 353 3.5E-154 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 Gene3D G3DSA:3.20.20.70 4 349 6.9E-64 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 SUPERFAMILY SSF102114 13 345 2.09E-52 T 12-10-2018 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 SMART SM00729 53 268 0.0032 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 12 356 51.776 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 Pfam PF04055 Radical SAM superfamily 58 230 1.1E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02950 ce3226ace35b67f52076df3c5c09e9ef 356 PIRSF PIRSF004762 7 356 3.6E-111 T 12-10-2018 THERU_08215 c8996986d780c9d62eeb6f7d9042ec96 202 SUPERFAMILY SSF54001 70 182 5.1E-43 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THERU_08215 c8996986d780c9d62eeb6f7d9042ec96 202 Pfam PF00877 NlpC/P60 family 74 177 2.8E-33 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain THERU_08215 c8996986d780c9d62eeb6f7d9042ec96 202 Gene3D G3DSA:3.90.1720.10 66 197 1.0E-42 T 12-10-2018 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 4 162 6.7E-41 T 12-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 Pfam PF00355 Rieske [2Fe-2S] domain 48 151 5.8E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 Gene3D G3DSA:2.102.10.10 37 163 1.0E-29 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 124 136 4.7E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 136 148 4.7E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 108 4.7E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THERU_06695 f0ab88afbce072e1e0c94a43ad7c5306 172 SUPERFAMILY SSF50022 26 163 7.11E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_07500 372c29c373decf0460d6e4366c1439e3 288 Pfam PF04468 PSP1 C-terminal conserved region 58 140 1.5E-25 T 12-10-2018 IPR007557 PSP1, C-terminal THERU_00030 7b70b9fa0ea44751a71bfcbd11de7e9d 342 PIRSF PIRSF000355 1 342 4.3E-114 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THERU_00030 7b70b9fa0ea44751a71bfcbd11de7e9d 342 SUPERFAMILY SSF47240 17 338 1.58E-82 T 12-10-2018 IPR009078 Ferritin-like superfamily THERU_00030 7b70b9fa0ea44751a71bfcbd11de7e9d 342 Gene3D G3DSA:1.10.620.20 5 316 2.7E-92 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 THERU_00030 7b70b9fa0ea44751a71bfcbd11de7e9d 342 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 118 134 - T 12-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THERU_00030 7b70b9fa0ea44751a71bfcbd11de7e9d 342 Pfam PF00268 Ribonucleotide reductase, small chain 30 309 2.6E-68 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THERU_06535 6e46fd6b6ec2d3d6d58ab7673ece637c 296 SUPERFAMILY SSF90002 226 291 6.8E-6 T 12-10-2018 THERU_06535 6e46fd6b6ec2d3d6d58ab7673ece637c 296 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 164 9.8E-44 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THERU_06535 6e46fd6b6ec2d3d6d58ab7673ece637c 296 SUPERFAMILY SSF52540 3 169 2.96E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06535 6e46fd6b6ec2d3d6d58ab7673ece637c 296 Gene3D G3DSA:3.40.50.300 1 179 1.7E-45 T 12-10-2018 THERU_06535 6e46fd6b6ec2d3d6d58ab7673ece637c 296 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 226 292 2.5E-6 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 Pfam PF00209 Sodium:neurotransmitter symporter family 160 464 1.4E-34 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 Pfam PF00209 Sodium:neurotransmitter symporter family 3 127 2.1E-20 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 3.0E-18 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 324 343 3.0E-18 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 395 415 3.0E-18 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 274 294 3.0E-18 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 3.0E-18 T 12-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THERU_03765 7ca346e976a1ea980e48d8e8cd3eb463 500 SUPERFAMILY SSF161070 3 484 2.48E-104 T 12-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 THERU_02155 3063dd47c5ec275a69679d27bbf4be65 1130 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 887 1098 1.9E-12 T 12-10-2018 IPR007452 Translocation and assembly module TamB THERU_01100 48969452b6bacb5ec7c819f6ff6e4712 473 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 21 225 7.6E-9 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THERU_01100 48969452b6bacb5ec7c819f6ff6e4712 473 SUPERFAMILY SSF46626 368 448 1.22E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_01100 48969452b6bacb5ec7c819f6ff6e4712 473 Gene3D G3DSA:1.10.760.10 352 450 6.3E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_03750 e176d09011828e9a71139baadfaf561c 414 SUPERFAMILY SSF51690 134 413 2.94E-90 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THERU_03750 e176d09011828e9a71139baadfaf561c 414 Gene3D G3DSA:3.20.20.70 151 306 1.9E-59 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03750 e176d09011828e9a71139baadfaf561c 414 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 367 1.2E-149 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 THERU_03750 e176d09011828e9a71139baadfaf561c 414 Gene3D G3DSA:3.20.140.10 1 150 1.8E-51 T 12-10-2018 THERU_03750 e176d09011828e9a71139baadfaf561c 414 Gene3D G3DSA:3.20.140.10 307 368 1.4E-8 T 12-10-2018 THERU_03750 e176d09011828e9a71139baadfaf561c 414 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 336 7.7E-14 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 THERU_03750 e176d09011828e9a71139baadfaf561c 414 SUPERFAMILY SSF54675 3 133 1.9E-41 T 12-10-2018 THERU_03750 e176d09011828e9a71139baadfaf561c 414 PIRSF PIRSF000484 1 414 3.3E-129 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 THERU_04455 0167fe9804a60469d216d83818132824 735 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 243 581 8.4E-85 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core THERU_04455 0167fe9804a60469d216d83818132824 735 SUPERFAMILY SSF52540 238 547 8.67E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04455 0167fe9804a60469d216d83818132824 735 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 21 199 9.3E-22 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain THERU_04455 0167fe9804a60469d216d83818132824 735 SMART SM00487 224 431 7.9E-10 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_04455 0167fe9804a60469d216d83818132824 735 Gene3D G3DSA:3.40.50.300 415 576 3.0E-15 T 12-10-2018 THERU_04455 0167fe9804a60469d216d83818132824 735 Gene3D G3DSA:3.40.50.300 208 414 3.1E-12 T 12-10-2018 THERU_04455 0167fe9804a60469d216d83818132824 735 SMART SM00490 462 545 6.7E-4 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_04455 0167fe9804a60469d216d83818132824 735 Gene3D G3DSA:1.10.3210.30 6 179 2.8E-20 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily THERU_04455 0167fe9804a60469d216d83818132824 735 Pfam PF00271 Helicase conserved C-terminal domain 440 545 2.2E-7 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 72 18.223 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 Gene3D G3DSA:4.10.640.10 2 72 3.1E-25 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 SUPERFAMILY SSF46911 5 70 5.75E-23 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 PRINTS PR00974 Ribosomal protein S18 family signature 59 69 1.2E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 PRINTS PR00974 Ribosomal protein S18 family signature 27 37 1.2E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 PRINTS PR00974 Ribosomal protein S18 family signature 45 59 1.2E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 PRINTS PR00974 Ribosomal protein S18 family signature 37 44 1.2E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 Pfam PF01084 Ribosomal protein S18 18 67 1.9E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 TIGRFAM TIGR00165 S18: ribosomal protein bS18 7 70 7.1E-25 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07870 6626d3ae1402f890eb5f2880b8b9d1b6 72 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 70 3.0E-13 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:1.20.1640.10 525 1053 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.70.1440 688 901 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82693 44 136 2.96E-21 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 374 395 5.4E-30 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 5.4E-30 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 482 505 5.4E-30 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 5.4E-30 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 402 426 5.4E-30 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.70.1320 138 344 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82693 139 340 8.2E-13 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82866 826 1055 4.84E-39 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:1.20.1640.10 20 524 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.70.1430 44 835 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.2090.10 182 272 3.3E-236 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.70.1430 579 687 3.3E-236 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82866 307 509 1.7E-39 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82714 186 268 9.16E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 SUPERFAMILY SSF82693 577 686 2.25E-11 T 12-10-2018 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Pfam PF00873 AcrB/AcrD/AcrF family 10 1055 2.3E-161 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THERU_07850 184616e1cd7e99b3d6d13045e32e601a 1075 Gene3D G3DSA:3.30.2090.10 739 827 3.3E-236 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THERU_06700 d89530272bddb8ea90fecc5006aca847 404 Gene3D G3DSA:1.20.810.10 2 401 4.6E-126 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 THERU_06700 d89530272bddb8ea90fecc5006aca847 404 SUPERFAMILY SSF81342 9 279 9.42E-73 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THERU_06700 d89530272bddb8ea90fecc5006aca847 404 SUPERFAMILY SSF81648 280 390 7.52E-29 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THERU_06700 d89530272bddb8ea90fecc5006aca847 404 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 277 377 5.5E-31 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THERU_06700 d89530272bddb8ea90fecc5006aca847 404 Pfam PF00033 Cytochrome b/b6/petB 24 220 2.2E-51 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 SUPERFAMILY SSF54814 252 315 5.43E-14 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 SUPERFAMILY SSF50249 104 171 8.15E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Pfam PF00575 S1 RNA binding domain 106 163 9.2E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 323 24.574 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Gene3D G3DSA:3.30.300.20 250 322 6.5E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Gene3D G3DSA:3.30.1480.10 1 96 2.8E-8 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 62 314 1.5E-84 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 SUPERFAMILY SSF69705 1 93 7.46E-13 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 SMART SM00316 105 172 1.5E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Gene3D G3DSA:3.30.300.20 171 249 1.9E-29 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Pfam PF13184 NusA-like KH domain 202 270 1.8E-22 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 SUPERFAMILY SSF54814 172 250 1.64E-26 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THERU_07690 2dd250491d7a0fc5d50d2082bed53c35 323 Gene3D G3DSA:2.40.50.140 107 170 3.5E-19 T 12-10-2018 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 ProSitePatterns PS00113 Adenylate kinase signature. 78 89 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 Hamap MF_00235 Adenylate kinase [adk]. 1 210 51.516 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 TIGRFAM TIGR01351 adk: adenylate kinase 3 208 7.2E-83 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 Pfam PF05191 Adenylate kinase, active site lid 124 159 3.7E-20 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 PRINTS PR00094 Adenylate kinase signature 4 17 1.6E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 PRINTS PR00094 Adenylate kinase signature 32 46 1.6E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 PRINTS PR00094 Adenylate kinase signature 174 188 1.6E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 PRINTS PR00094 Adenylate kinase signature 78 94 1.6E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 PRINTS PR00094 Adenylate kinase signature 157 172 1.6E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 Pfam PF00406 Adenylate kinase 6 187 5.4E-56 T 12-10-2018 THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 SUPERFAMILY SSF52540 2 209 2.41E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01500 1cdea51ad2e06c459373056edfd983a0 212 Gene3D G3DSA:3.40.50.300 1 209 1.6E-85 T 12-10-2018 THERU_03275 7595c0b8357bbdc9cb2811851aefa594 425 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 6 396 3.9E-12 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_03275 7595c0b8357bbdc9cb2811851aefa594 425 SUPERFAMILY SSF81442 5 420 8.76E-21 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_03275 7595c0b8357bbdc9cb2811851aefa594 425 Gene3D G3DSA:1.20.210.10 3 425 1.2E-34 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_06550 f913184bc3c09299a8139b8c1ddd6ec2 118 Pfam PF00543 Nitrogen regulatory protein P-II 12 99 1.6E-9 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_06550 f913184bc3c09299a8139b8c1ddd6ec2 118 SUPERFAMILY SSF54913 5 104 3.06E-21 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THERU_06550 f913184bc3c09299a8139b8c1ddd6ec2 118 SMART SM00938 12 106 0.0016 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THERU_06550 f913184bc3c09299a8139b8c1ddd6ec2 118 Gene3D G3DSA:3.30.70.120 1 107 9.9E-36 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THERU_01580 5a3f2428d52b950577b42c30c02c1361 263 SUPERFAMILY SSF110849 13 93 9.03E-15 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily THERU_01580 5a3f2428d52b950577b42c30c02c1361 263 Gene3D G3DSA:3.90.1530.10 5 97 1.8E-8 T 12-10-2018 THERU_01580 5a3f2428d52b950577b42c30c02c1361 263 SMART SM00470 19 103 1.6E-9 T 12-10-2018 IPR003115 ParB/Sulfiredoxin THERU_01580 5a3f2428d52b950577b42c30c02c1361 263 Pfam PF02195 ParB-like nuclease domain 22 90 6.8E-12 T 12-10-2018 IPR003115 ParB/Sulfiredoxin THERU_06065 e84deae42a6105db1f2d152792471432 443 SUPERFAMILY SSF52540 60 280 7.33E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06065 e84deae42a6105db1f2d152792471432 443 SMART SM00382 82 236 1.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_06065 e84deae42a6105db1f2d152792471432 443 Hamap MF_01498 DNA repair protein RadA [radA]. 21 443 41.68 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THERU_06065 e84deae42a6105db1f2d152792471432 443 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 439 2.2E-162 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 166 190 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 205 233 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 74 102 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 116 133 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 313 336 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 240 266 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 PRINTS PR01874 DNA repair protein radA signature 10 34 5.9E-88 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 SUPERFAMILY SSF54211 247 443 3.64E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_06065 e84deae42a6105db1f2d152792471432 443 Pfam PF13481 AAA domain 73 214 1.5E-14 T 12-10-2018 THERU_06065 e84deae42a6105db1f2d152792471432 443 Gene3D G3DSA:3.30.230.10 321 443 1.2E-14 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_06065 e84deae42a6105db1f2d152792471432 443 Gene3D G3DSA:3.40.50.300 57 273 5.2E-45 T 12-10-2018 THERU_06705 94dea4991e81e3c0c2cd9e3f2d235844 209 Pfam PF00034 Cytochrome c 46 166 3.7E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_06705 94dea4991e81e3c0c2cd9e3f2d235844 209 SUPERFAMILY SSF46626 35 168 2.3E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Gene3D G3DSA:2.40.30.170 261 373 6.1E-34 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Gene3D G3DSA:1.10.287.470 129 212 3.2E-7 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 SUPERFAMILY SSF111369 193 305 9.02E-12 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 SUPERFAMILY SSF111369 40 98 1.22E-5 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Gene3D G3DSA:1.10.287.470 78 113 1.7E-10 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Gene3D G3DSA:2.40.50.100 43 77 1.7E-10 T 12-10-2018 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Pfam PF00529 HlyD membrane-fusion protein of T1SS 323 370 5.5E-9 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THERU_00465 04ce6ceff49239b969bcb5f96873b4a1 373 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 37 322 1.2E-18 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THERU_00410 36c69ccd34c789083976c0f6f6f60e90 453 SMART SM00316 37 100 7.7E-4 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_00410 36c69ccd34c789083976c0f6f6f60e90 453 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 18 392 1.5E-104 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THERU_00410 36c69ccd34c789083976c0f6f6f60e90 453 SUPERFAMILY SSF50249 39 105 1.96E-10 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_00410 36c69ccd34c789083976c0f6f6f60e90 453 Gene3D G3DSA:2.40.50.140 30 73 1.9E-7 T 12-10-2018 THERU_00410 36c69ccd34c789083976c0f6f6f60e90 453 Pfam PF10150 Ribonuclease E/G family 103 366 2.8E-81 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THERU_04085 01ab42f47109776b1887427acf937dda 336 SUPERFAMILY SSF52540 15 200 5.69E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04085 01ab42f47109776b1887427acf937dda 336 Gene3D G3DSA:1.20.272.10 203 329 8.8E-21 T 12-10-2018 THERU_04085 01ab42f47109776b1887427acf937dda 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 47 316 3.3E-36 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 THERU_04085 01ab42f47109776b1887427acf937dda 336 Gene3D G3DSA:1.10.8.60 134 200 2.6E-9 T 12-10-2018 THERU_04085 01ab42f47109776b1887427acf937dda 336 Gene3D G3DSA:3.40.50.300 3 133 1.4E-6 T 12-10-2018 THERU_04085 01ab42f47109776b1887427acf937dda 336 Pfam PF06144 DNA polymerase III, delta subunit 79 184 2.3E-8 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 THERU_04085 01ab42f47109776b1887427acf937dda 336 SUPERFAMILY SSF48019 206 325 2.13E-15 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THERU_04000 13321c70a62a6a1bd4878884e83670a6 344 SUPERFAMILY SSF53756 6 325 1.33E-41 T 12-10-2018 THERU_04000 13321c70a62a6a1bd4878884e83670a6 344 Gene3D G3DSA:3.40.50.2000 1 173 8.0E-13 T 12-10-2018 THERU_04000 13321c70a62a6a1bd4878884e83670a6 344 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 88 320 1.9E-15 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THERU_04000 13321c70a62a6a1bd4878884e83670a6 344 Gene3D G3DSA:3.40.50.2000 177 339 9.9E-25 T 12-10-2018 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 Gene3D G3DSA:3.40.50.1400 3 310 5.1E-108 T 12-10-2018 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 ProSitePatterns PS00534 Ferrochelatase signature. 182 200 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 Pfam PF00762 Ferrochelatase 3 309 3.8E-110 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 Hamap MF_00323 Ferrochelatase [hemH]. 2 311 36.422 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 SUPERFAMILY SSF53800 1 315 7.68E-107 T 12-10-2018 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 Gene3D G3DSA:3.40.50.1400 157 292 5.1E-108 T 12-10-2018 THERU_05980 6dad43f7e00bcf6d917d5abf9a4baa57 328 TIGRFAM TIGR00109 hemH: ferrochelatase 2 310 1.3E-98 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THERU_02160 4b16ba38b6e86ef09a851aaccd6676f0 204 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 22 115 8.2E-23 T 12-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 Pfam PF00166 Chaperonin 10 Kd subunit 3 95 2.1E-35 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 Hamap MF_00580 10 kDa chaperonin [groS]. 3 97 27.364 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 Gene3D G3DSA:2.30.33.40 1 97 2.6E-37 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 PRINTS PR00297 10kDa chaperonin signature 27 48 1.9E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 PRINTS PR00297 10kDa chaperonin signature 4 19 1.9E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 PRINTS PR00297 10kDa chaperonin signature 62 74 1.9E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 PRINTS PR00297 10kDa chaperonin signature 83 96 1.9E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 SUPERFAMILY SSF50129 2 97 2.66E-34 T 12-10-2018 IPR011032 GroES-like superfamily THERU_06900 f8fb489f1e8acb0aa6def152a3f840b1 97 SMART SM00883 3 96 1.2E-55 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THERU_04710 a6ffab3e630574a594e872ac7af5888a 276 SUPERFAMILY SSF46626 51 156 8.1E-9 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_04710 a6ffab3e630574a594e872ac7af5888a 276 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 53 275 6.1E-65 T 12-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 THERU_04710 a6ffab3e630574a594e872ac7af5888a 276 Gene3D G3DSA:1.10.760.10 53 149 2.0E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_04710 a6ffab3e630574a594e872ac7af5888a 276 Gene3D G3DSA:1.10.760.10 150 276 2.8E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_04710 a6ffab3e630574a594e872ac7af5888a 276 SUPERFAMILY SSF46626 160 274 3.45E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THERU_02675 501a10d7c7a2e895675301389e9db772 201 Gene3D G3DSA:2.50.20.10 17 199 2.3E-35 T 12-10-2018 THERU_02675 501a10d7c7a2e895675301389e9db772 201 SUPERFAMILY SSF89392 18 198 4.32E-28 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THERU_02675 501a10d7c7a2e895675301389e9db772 201 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 27 189 5.0E-28 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 Pfam PF13662 Toprim domain 84 175 5.2E-24 T 12-10-2018 IPR006171 TOPRIM domain THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 Pfam PF02132 RecR protein 44 80 1.5E-11 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 Hamap MF_00017 Recombination protein RecR [recR]. 1 203 76.365 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 Gene3D G3DSA:3.40.1360.10 80 203 2.9E-40 T 12-10-2018 THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 TIGRFAM TIGR00615 recR: recombination protein RecR 6 200 7.9E-72 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 ProSitePatterns PS01300 RecR protein signature. 60 81 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 SUPERFAMILY SSF111304 6 203 3.01E-59 T 12-10-2018 IPR023627 Recombination protein RecR THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 Gene3D G3DSA:1.10.8.420 2 56 1.8E-7 T 12-10-2018 THERU_03800 2ee63731db7d97eb9c148b98eb14920f 204 SMART SM00493 83 168 1.1E-13 T 12-10-2018 IPR006171 TOPRIM domain THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 SMART SM00382 356 535 8.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 Gene3D G3DSA:1.20.1560.10 2 321 1.1E-53 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 SUPERFAMILY SSF52540 326 544 8.32E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 Gene3D G3DSA:3.40.50.300 323 553 9.9E-70 T 12-10-2018 THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 Pfam PF00005 ABC transporter 347 490 4.4E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 SUPERFAMILY SSF90123 7 318 3.27E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THERU_07730 07ad082dcd74064fb66093e54c13ebe0 560 Pfam PF00664 ABC transporter transmembrane region 16 289 4.3E-41 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THERU_01330 0a026c784ccfb6855c1d094108f48b7f 372 SUPERFAMILY SSF109604 2 362 9.95E-77 T 12-10-2018 THERU_01330 0a026c784ccfb6855c1d094108f48b7f 372 Gene3D G3DSA:1.10.3210.10 1 281 3.6E-84 T 12-10-2018 THERU_01330 0a026c784ccfb6855c1d094108f48b7f 372 Pfam PF01966 HD domain 51 157 2.4E-14 T 12-10-2018 IPR006674 HD domain THERU_01330 0a026c784ccfb6855c1d094108f48b7f 372 Gene3D G3DSA:3.30.70.1370 282 371 2.1E-18 T 12-10-2018 THERU_01330 0a026c784ccfb6855c1d094108f48b7f 372 SMART SM00471 47 177 8.0E-13 T 12-10-2018 IPR003607 HD/PDEase domain THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 PRINTS PR01650 Bacterial translocase SecE signature 1 21 1.7E-6 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 PRINTS PR01650 Bacterial translocase SecE signature 25 45 1.7E-6 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 PRINTS PR01650 Bacterial translocase SecE signature 45 61 1.7E-6 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 Gene3D G3DSA:1.20.5.1030 1 58 1.1E-17 T 12-10-2018 IPR038379 SecE superfamily THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 4 59 2.7E-14 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 57 12.635 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_07265 4856465ec6a33ee40a2c26ad4afb4ba2 64 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 58 4.1E-17 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 SUPERFAMILY SSF53955 40 260 7.03E-81 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 Gene3D G3DSA:3.40.710.10 249 321 3.8E-9 T 12-10-2018 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 Gene3D G3DSA:3.40.710.10 377 719 2.8E-109 T 12-10-2018 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 Pfam PF00905 Penicillin binding protein transpeptidase domain 396 632 6.2E-29 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 Pfam PF00912 Transglycosylase 54 227 3.1E-66 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 63 668 2.2E-199 T 12-10-2018 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 Gene3D G3DSA:1.10.3810.10 46 243 5.2E-82 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_06120 e6cf4285f462bc424a15fa776eab9951 740 SUPERFAMILY SSF56601 209 691 3.76E-123 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THERU_06895 67fde2b478396693009e3f88a41c3774 163 Gene3D G3DSA:1.20.120.1760 1 163 8.6E-16 T 12-10-2018 THERU_06895 67fde2b478396693009e3f88a41c3774 163 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 64 1.4E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_06895 67fde2b478396693009e3f88a41c3774 163 PIRSF PIRSF000847 1 163 3.2E-37 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THERU_06895 67fde2b478396693009e3f88a41c3774 163 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 42 64 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Pfam PF01568 Molydopterin dinucleotide binding domain 740 844 3.0E-22 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 SUPERFAMILY SSF53706 9 712 3.7E-146 T 12-10-2018 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Gene3D G3DSA:3.30.200.200 13 693 1.0E-261 T 12-10-2018 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Gene3D G3DSA:3.40.228.10 206 711 1.0E-261 T 12-10-2018 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Pfam PF00384 Molybdopterin oxidoreductase 123 604 4.5E-43 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 SUPERFAMILY SSF50692 697 851 5.42E-38 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Gene3D G3DSA:3.40.50.740 124 656 1.0E-261 T 12-10-2018 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 Gene3D G3DSA:2.40.40.20 728 863 7.0E-44 T 12-10-2018 THERU_04630 90950b5dae3cf2b6eb82305f36ccfaf6 873 TIGRFAM TIGR02693 arsenite_ox_L: arsenite oxidase, large subunit 9 852 0.0 T 12-10-2018 IPR014066 Arsenite oxidase, large subunit MetaCyc: PWY-7429 THERU_06865 d2b86d13550ae021118706c4144d1d37 355 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 18 355 46.699 T 12-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 THERU_06865 d2b86d13550ae021118706c4144d1d37 355 Gene3D G3DSA:1.10.10.10 3 87 5.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_06865 d2b86d13550ae021118706c4144d1d37 355 Gene3D G3DSA:3.40.50.150 107 331 1.5E-71 T 12-10-2018 THERU_06865 d2b86d13550ae021118706c4144d1d37 355 Pfam PF01861 Protein of unknown function DUF43 110 354 5.0E-103 T 12-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal THERU_06865 d2b86d13550ae021118706c4144d1d37 355 PIRSF PIRSF005895 1 355 6.0E-138 T 12-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 THERU_06865 d2b86d13550ae021118706c4144d1d37 355 SUPERFAMILY SSF53335 126 258 1.1E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_00260 33785be4ceed785b0532384d01df6132 407 Gene3D G3DSA:3.10.580.10 180 319 1.5E-27 T 12-10-2018 THERU_00260 33785be4ceed785b0532384d01df6132 407 SUPERFAMILY SSF56176 327 405 5.18E-22 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THERU_00260 33785be4ceed785b0532384d01df6132 407 SMART SM01091 328 406 1.4E-25 T 12-10-2018 IPR005170 Transporter-associated domain THERU_00260 33785be4ceed785b0532384d01df6132 407 SUPERFAMILY SSF54631 189 315 2.4E-22 T 12-10-2018 THERU_00260 33785be4ceed785b0532384d01df6132 407 Pfam PF03471 Transporter associated domain 329 404 1.0E-22 T 12-10-2018 IPR005170 Transporter-associated domain THERU_00260 33785be4ceed785b0532384d01df6132 407 Pfam PF00571 CBS domain 264 313 5.3E-6 T 12-10-2018 IPR000644 CBS domain THERU_00260 33785be4ceed785b0532384d01df6132 407 Pfam PF00571 CBS domain 203 252 2.4E-6 T 12-10-2018 IPR000644 CBS domain THERU_00260 33785be4ceed785b0532384d01df6132 407 Gene3D G3DSA:3.30.465.10 320 405 1.5E-23 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THERU_00260 33785be4ceed785b0532384d01df6132 407 Pfam PF01595 Domain of unknown function DUF21 9 180 1.3E-26 T 12-10-2018 IPR002550 CNNM, transmembrane domain THERU_00260 33785be4ceed785b0532384d01df6132 407 SMART SM00116 206 255 0.41 T 12-10-2018 IPR000644 CBS domain THERU_00260 33785be4ceed785b0532384d01df6132 407 SMART SM00116 266 314 2.0 T 12-10-2018 IPR000644 CBS domain THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 Pfam PF00293 NUDIX domain 13 133 1.2E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 PRINTS PR00502 NUDIX hydrolase family signature 52 67 3.1E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 PRINTS PR00502 NUDIX hydrolase family signature 38 52 3.1E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 SUPERFAMILY SSF55811 3 135 1.62E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THERU_05190 717e5ecea4db67f93b69bee9a69c2a9b 137 Gene3D G3DSA:3.90.79.10 1 136 1.8E-42 T 12-10-2018 THERU_08160 8d188b1489d79650705082d524cac7be 250 Hamap MF_01499 Diadenylate cyclase [dacA]. 6 247 31.681 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 THERU_08160 8d188b1489d79650705082d524cac7be 250 PIRSF PIRSF004793 2 249 1.4E-88 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 THERU_08160 8d188b1489d79650705082d524cac7be 250 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 111 228 9.2E-42 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal THERU_08160 8d188b1489d79650705082d524cac7be 250 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 9 242 3.1E-70 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 THERU_08160 8d188b1489d79650705082d524cac7be 250 SUPERFAMILY SSF143597 37 234 9.15E-65 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily THERU_08160 8d188b1489d79650705082d524cac7be 250 Gene3D G3DSA:3.40.1700.10 96 247 1.3E-59 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily THERU_00730 6fe03b9cd0832e2b3588334ac9044dcb 443 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 225 422 5.8E-19 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 THERU_00730 6fe03b9cd0832e2b3588334ac9044dcb 443 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 14 106 6.1E-15 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 THERU_08220 4c582026b5620e41c14806992f526c3d 192 Gene3D G3DSA:1.20.120.1760 9 190 3.1E-52 T 12-10-2018 THERU_08220 4c582026b5620e41c14806992f526c3d 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 70 92 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_08220 4c582026b5620e41c14806992f526c3d 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 92 1.6E-16 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_02335 0d4fb5059a7f7305b4d99ee2781d61b8 415 SUPERFAMILY SSF109604 183 410 9.42E-38 T 12-10-2018 THERU_02335 0d4fb5059a7f7305b4d99ee2781d61b8 415 Pfam PF08668 HDOD domain 202 325 6.8E-25 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD THERU_02335 0d4fb5059a7f7305b4d99ee2781d61b8 415 Gene3D G3DSA:1.10.3210.10 194 381 1.9E-31 T 12-10-2018 THERU_02335 0d4fb5059a7f7305b4d99ee2781d61b8 415 PIRSF PIRSF003180 1 389 9.1E-77 T 12-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing THERU_02335 0d4fb5059a7f7305b4d99ee2781d61b8 415 SUPERFAMILY SSF141868 3 199 2.75E-10 T 12-10-2018 IPR035919 EAL domain superfamily THERU_01610 850a10234179de750de08b74a4019155 369 Pfam PF00534 Glycosyl transferases group 1 191 323 4.8E-20 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_01610 850a10234179de750de08b74a4019155 369 Gene3D G3DSA:3.40.50.2000 188 344 2.4E-25 T 12-10-2018 THERU_01610 850a10234179de750de08b74a4019155 369 SUPERFAMILY SSF53756 4 360 6.63E-55 T 12-10-2018 THERU_01610 850a10234179de750de08b74a4019155 369 Gene3D G3DSA:3.40.50.2000 1 187 3.9E-17 T 12-10-2018 THERU_01610 850a10234179de750de08b74a4019155 369 Pfam PF13439 Glycosyltransferase Family 4 15 175 1.3E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_06940 d4d16af9e0711bfcb32033a490035141 319 SUPERFAMILY SSF53659 3 318 9.32E-89 T 12-10-2018 THERU_06940 d4d16af9e0711bfcb32033a490035141 319 Gene3D G3DSA:3.40.718.10 1 318 9.1E-109 T 12-10-2018 THERU_06940 d4d16af9e0711bfcb32033a490035141 319 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 3 314 9.1E-98 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 THERU_06940 d4d16af9e0711bfcb32033a490035141 319 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 32 310 1.0E-88 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 Pfam PF01555 DNA methylase 28 231 4.5E-37 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 SUPERFAMILY SSF53335 7 235 1.08E-57 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 27 41 7.1E-28 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 192 210 7.1E-28 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 172 189 7.1E-28 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 235 7.1E-28 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 72 92 7.1E-28 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 32 37 - T 12-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 THERU_08030 14e4c9ba731cca406a1922a6a2ffb0b2 270 Gene3D G3DSA:3.40.50.150 4 257 9.2E-63 T 12-10-2018 THERU_05685 078183d805a937732dacbc4cb7f9ddb5 142 SUPERFAMILY SSF101307 3 141 7.32E-27 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 THERU_05685 078183d805a937732dacbc4cb7f9ddb5 142 Pfam PF04608 Phosphatidylglycerophosphatase A 4 141 2.5E-38 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THERU_05685 078183d805a937732dacbc4cb7f9ddb5 142 PIRSF PIRSF006162 1 142 7.5E-39 T 12-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THERU_06935 a637ddf767749dcd4943dcee196e863d 222 Pfam PF13192 Thioredoxin domain 133 210 1.7E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_06935 a637ddf767749dcd4943dcee196e863d 222 Pfam PF13192 Thioredoxin domain 33 97 5.0E-6 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_06935 a637ddf767749dcd4943dcee196e863d 222 SUPERFAMILY SSF52833 3 115 2.2E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_06935 a637ddf767749dcd4943dcee196e863d 222 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 3 212 5.3E-77 T 12-10-2018 IPR011903 Glutaredoxin-like domain THERU_06935 a637ddf767749dcd4943dcee196e863d 222 Gene3D G3DSA:3.40.30.10 112 220 9.3E-23 T 12-10-2018 THERU_06935 a637ddf767749dcd4943dcee196e863d 222 Gene3D G3DSA:3.40.30.10 1 111 1.1E-34 T 12-10-2018 THERU_06935 a637ddf767749dcd4943dcee196e863d 222 SUPERFAMILY SSF52833 123 210 4.02E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 Gene3D G3DSA:1.10.8.100 183 241 2.8E-13 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 2 237 1.2E-61 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 1 241 41.136 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 SUPERFAMILY SSF53335 2 237 8.13E-54 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 Gene3D G3DSA:3.40.50.150 1 180 1.9E-55 T 12-10-2018 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 61 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 SMART SM00650 17 180 3.7E-57 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 THERU_02410 50eac8de0f6237d5f0a3247c1c739282 242 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 234 1.2E-48 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm THERU_05390 d7ff32424e7730fb28f031a3b0b71090 128 SUPERFAMILY SSF55298 1 127 6.91E-45 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THERU_05390 d7ff32424e7730fb28f031a3b0b71090 128 Gene3D G3DSA:3.30.1330.40 1 127 4.5E-48 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THERU_05390 d7ff32424e7730fb28f031a3b0b71090 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 125 9.5E-44 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 THERU_05390 d7ff32424e7730fb28f031a3b0b71090 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 THERU_05390 d7ff32424e7730fb28f031a3b0b71090 128 Pfam PF01042 Endoribonuclease L-PSP 8 125 1.4E-39 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 Gene3D G3DSA:3.30.1360.120 11 291 1.6E-45 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 PIRSF PIRSF006487 168 287 2.3E-5 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 PIRSF PIRSF006487 23 164 9.6E-9 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 SUPERFAMILY SSF103025 28 227 8.95E-39 T 12-10-2018 THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 Pfam PF01571 Aminomethyltransferase folate-binding domain 27 159 1.7E-12 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 174 237 3.0E-20 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site THERU_08050 e7e87512f0d355a7f2aea7dfe6e1e922 292 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 212 281 1.2E-9 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 SUPERFAMILY SSF51569 1 213 9.52E-81 T 12-10-2018 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 Gene3D G3DSA:3.20.20.70 1 215 9.7E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 4.3E-109 T 12-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.32 T 12-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 THERU_06930 dcce178f3bd09682d6a1c966f4d42e77 217 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 202 4.0E-60 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 517 527 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 Gene3D G3DSA:3.40.50.200 395 575 1.8E-31 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 2.9E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 PRINTS PR00723 Subtilisin serine protease family (S8) signature 217 230 2.9E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 PRINTS PR00723 Subtilisin serine protease family (S8) signature 516 532 2.9E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 SUPERFAMILY SSF52743 37 569 9.69E-59 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 Pfam PF00082 Subtilase family 443 569 4.0E-21 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 Gene3D G3DSA:3.40.50.200 149 385 3.7E-40 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THERU_01285 cb55d10f00c5af2008d37ff42a111e52 640 Pfam PF00082 Subtilase family 160 319 3.6E-17 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THERU_05595 0679ef803dcf86429275d46fa7ffae2c 188 Pfam PF02581 Thiamine monophosphate synthase 4 180 7.0E-56 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_05595 0679ef803dcf86429275d46fa7ffae2c 188 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 2 188 19.08 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_05595 0679ef803dcf86429275d46fa7ffae2c 188 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 3 181 4.8E-46 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_05595 0679ef803dcf86429275d46fa7ffae2c 188 SUPERFAMILY SSF51391 1 184 1.06E-59 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_05595 0679ef803dcf86429275d46fa7ffae2c 188 Gene3D G3DSA:3.20.20.70 2 187 5.6E-65 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02715 5934aba3e3ca1db7f68eec08fcf83fda 252 SUPERFAMILY SSF52540 2 247 1.07E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02715 5934aba3e3ca1db7f68eec08fcf83fda 252 Gene3D G3DSA:3.40.50.300 1 251 5.2E-82 T 12-10-2018 THERU_02715 5934aba3e3ca1db7f68eec08fcf83fda 252 Pfam PF00005 ABC transporter 18 173 6.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_02715 5934aba3e3ca1db7f68eec08fcf83fda 252 SMART SM00382 27 222 3.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_05500 c95fe49b2fe00cd63d130fbbbcaf7db8 406 PIRSF PIRSF005572 8 391 1.6E-121 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 THERU_05500 c95fe49b2fe00cd63d130fbbbcaf7db8 406 Gene3D G3DSA:3.40.640.10 22 266 3.3E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_05500 c95fe49b2fe00cd63d130fbbbcaf7db8 406 Pfam PF00266 Aminotransferase class-V 11 376 1.3E-82 T 12-10-2018 IPR000192 Aminotransferase class V domain THERU_05500 c95fe49b2fe00cd63d130fbbbcaf7db8 406 Gene3D G3DSA:3.90.1150.10 11 383 3.3E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_05500 c95fe49b2fe00cd63d130fbbbcaf7db8 406 SUPERFAMILY SSF53383 10 384 1.69E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 256 1.8E-90 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 Gene3D G3DSA:3.90.230.10 1 257 1.9E-89 T 12-10-2018 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 72 85 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 Pfam PF00557 Metallopeptidase family M24 11 247 8.1E-49 T 12-10-2018 IPR000994 Peptidase M24 THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 SUPERFAMILY SSF55920 8 256 7.33E-76 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like THERU_01505 40bf1377b9b1a4a5a9d1a2b2a0195fd9 262 Hamap MF_01974 Methionine aminopeptidase [map]. 1 257 36.973 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 135 2.5E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 SUPERFAMILY SSF51735 143 316 4.07E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 SUPERFAMILY SSF50129 1 175 9.74E-48 T 12-10-2018 IPR011032 GroES-like superfamily THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 SMART SM00829 10 340 2.1E-34 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 Gene3D G3DSA:3.40.50.720 149 290 8.9E-116 T 12-10-2018 THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 Pfam PF00107 Zinc-binding dehydrogenase 179 296 5.2E-37 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THERU_06190 c6cb3893b2f2862ecb3abcf5ea557967 343 Gene3D G3DSA:3.90.180.10 18 333 8.9E-116 T 12-10-2018 THERU_06670 ef05d53b28abc1b6755fb4a9c74aca79 158 Pfam PF09335 SNARE associated Golgi protein 44 151 2.3E-15 T 12-10-2018 IPR032816 SNARE associated Golgi protein THERU_00155 6180fe066f3a95dbc51110d00a357e9b 176 SUPERFAMILY SSF75169 4 168 3.34E-18 T 12-10-2018 IPR027396 DsrEFH-like THERU_00155 6180fe066f3a95dbc51110d00a357e9b 176 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 173 2.4E-53 T 12-10-2018 IPR032836 DsrE2-like family THERU_05775 7135cd33e096e9a30602e2aaecb3c5e6 136 Gene3D G3DSA:3.30.700.10 5 132 2.8E-18 T 12-10-2018 THERU_05775 7135cd33e096e9a30602e2aaecb3c5e6 136 SUPERFAMILY SSF54523 5 89 4.97E-16 T 12-10-2018 THERU_05775 7135cd33e096e9a30602e2aaecb3c5e6 136 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 1.0E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05775 7135cd33e096e9a30602e2aaecb3c5e6 136 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05775 7135cd33e096e9a30602e2aaecb3c5e6 136 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 4.6E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05230 c69d3c286d557ff5da60da83f9d4521c 197 SUPERFAMILY SSF56524 14 197 2.62E-59 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 THERU_05230 c69d3c286d557ff5da60da83f9d4521c 197 Gene3D G3DSA:3.90.420.10 27 196 8.2E-48 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 THERU_05230 c69d3c286d557ff5da60da83f9d4521c 197 Pfam PF00174 Oxidoreductase molybdopterin binding domain 35 179 3.2E-39 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 THERU_03200 9bfa5a044318c88c97457e3956a19495 159 Gene3D G3DSA:3.40.50.10090 81 159 2.6E-10 T 12-10-2018 THERU_03200 9bfa5a044318c88c97457e3956a19495 159 Pfam PF02602 Uroporphyrinogen-III synthase HemD 2 152 3.6E-30 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_03200 9bfa5a044318c88c97457e3956a19495 159 SUPERFAMILY SSF69618 2 157 5.1E-31 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_03200 9bfa5a044318c88c97457e3956a19495 159 Gene3D G3DSA:3.40.50.10090 1 77 4.3E-12 T 12-10-2018 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 Pfam PF03466 LysR substrate binding domain 92 295 1.1E-31 T 12-10-2018 IPR005119 LysR, substrate-binding THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 Gene3D G3DSA:1.10.10.10 2 92 5.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 Gene3D G3DSA:3.40.190.290 93 304 8.8E-33 T 12-10-2018 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 SUPERFAMILY SSF46785 1 111 2.42E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_03505 d8251dc7caa540673e835a6f1541b58c 309 SUPERFAMILY SSF53850 92 298 1.57E-31 T 12-10-2018 THERU_01540 e631ca1ed606c2106ff7b7182b45347d 118 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 118 1.9E-37 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01540 e631ca1ed606c2106ff7b7182b45347d 118 SUPERFAMILY SSF64263 1 117 8.89E-43 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01540 e631ca1ed606c2106ff7b7182b45347d 118 Gene3D G3DSA:3.90.1030.10 1 118 9.8E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01540 e631ca1ed606c2106ff7b7182b45347d 118 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 117 26.78 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01540 e631ca1ed606c2106ff7b7182b45347d 118 Pfam PF01196 Ribosomal protein L17 20 117 1.4E-32 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_04010 94c2be38db48ae46f74debcf21ef06b2 294 SUPERFAMILY SSF53335 28 217 2.68E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_04010 94c2be38db48ae46f74debcf21ef06b2 294 Gene3D G3DSA:3.40.50.150 9 203 9.8E-37 T 12-10-2018 THERU_04010 94c2be38db48ae46f74debcf21ef06b2 294 Pfam PF13489 Methyltransferase domain 30 188 2.2E-26 T 12-10-2018 THERU_03830 a43313918ac3321a1b6960710472f609 389 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 3 389 2.8E-60 T 12-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 THERU_03830 a43313918ac3321a1b6960710472f609 389 Gene3D G3DSA:1.20.1330.10 39 200 3.9E-25 T 12-10-2018 THERU_03830 a43313918ac3321a1b6960710472f609 389 SUPERFAMILY SSF64518 1 389 1.83E-38 T 12-10-2018 THERU_03830 a43313918ac3321a1b6960710472f609 389 Pfam PF00669 Bacterial flagellin N-terminal helical region 18 139 1.5E-6 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THERU_03830 a43313918ac3321a1b6960710472f609 389 Pfam PF00700 Bacterial flagellin C-terminal helical region 310 389 4.5E-5 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 41.674 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 SMART SM01209 99 291 1.9E-123 T 12-10-2018 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Gene3D G3DSA:3.30.470.20 187 322 8.1E-53 T 12-10-2018 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Gene3D G3DSA:3.40.50.20 2 91 2.9E-34 T 12-10-2018 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 99 291 3.7E-74 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 SMART SM01210 323 416 2.1E-56 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 98 4.9E-34 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 325 414 4.6E-32 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 SUPERFAMILY SSF51246 322 416 5.23E-34 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Gene3D G3DSA:3.90.600.10 323 418 1.2E-39 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 285 292 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 8.5E-168 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 Gene3D G3DSA:3.30.1490.20 117 186 5.8E-25 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 SUPERFAMILY SSF56059 100 317 3.71E-59 T 12-10-2018 THERU_05480 62e76db1bc61f52fb2a2b799aa0b27c6 419 SUPERFAMILY SSF52440 2 99 3.74E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_01360 ca3d803c03acbf67f0b2e049ec48a5dd 147 Pfam PF00692 dUTPase 16 146 4.7E-33 T 12-10-2018 IPR029054 dUTPase-like THERU_01360 ca3d803c03acbf67f0b2e049ec48a5dd 147 Gene3D G3DSA:2.70.40.10 2 146 2.0E-55 T 12-10-2018 IPR036157 dUTPase-like superfamily THERU_01360 ca3d803c03acbf67f0b2e049ec48a5dd 147 TIGRFAM TIGR00576 dut: dUTP diphosphatase 6 147 9.9E-54 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 THERU_01360 ca3d803c03acbf67f0b2e049ec48a5dd 147 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 2 147 35.771 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 THERU_01360 ca3d803c03acbf67f0b2e049ec48a5dd 147 SUPERFAMILY SSF51283 3 147 7.07E-53 T 12-10-2018 IPR036157 dUTPase-like superfamily THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 Gene3D G3DSA:1.10.10.1590 4 70 5.5E-13 T 12-10-2018 THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 12 154 5.3E-48 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 SUPERFAMILY SSF52833 3 153 2.46E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 15 153 1.2E-42 T 12-10-2018 THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 111 129 - T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 PIRSF PIRSF000216 2 154 3.0E-48 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02320 f9ccd294ded03b335af62a6a37c699ed 154 Gene3D G3DSA:3.40.30.10 74 154 6.2E-23 T 12-10-2018 THERU_01955 3bcd12981ec0a66d8a21cd631641caca 170 SUPERFAMILY SSF50475 11 159 1.42E-22 T 12-10-2018 THERU_01955 3bcd12981ec0a66d8a21cd631641caca 170 Gene3D G3DSA:2.30.110.10 4 168 1.2E-31 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 THERU_01955 3bcd12981ec0a66d8a21cd631641caca 170 SMART SM00903 11 159 1.3E-4 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 THERU_01955 3bcd12981ec0a66d8a21cd631641caca 170 Pfam PF01613 Flavin reductase like domain 12 143 1.9E-17 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 THERU_00345 90535408669cd0e2a540937ed6f4bbab 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 280 4.1E-61 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THERU_00345 90535408669cd0e2a540937ed6f4bbab 299 Gene3D G3DSA:1.20.1510.10 20 217 1.6E-27 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THERU_00345 90535408669cd0e2a540937ed6f4bbab 299 SUPERFAMILY SSF161111 18 218 2.75E-46 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THERU_00345 90535408669cd0e2a540937ed6f4bbab 299 Pfam PF01545 Cation efflux family 24 217 3.3E-36 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 Gene3D G3DSA:3.40.1350.30 122 256 2.4E-76 T 12-10-2018 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 12 412 7.9E-81 T 12-10-2018 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 SUPERFAMILY SSF53335 62 417 4.26E-60 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 402 412 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 Gene3D G3DSA:2.40.50.140 2 73 7.3E-16 T 12-10-2018 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 Gene3D G3DSA:3.40.50.150 74 414 2.4E-76 T 12-10-2018 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 83 415 5.2E-25 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 350 381 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site THERU_07685 dfe997360c9d9e67820bd4cd6bbc55ed 419 SUPERFAMILY SSF50249 4 55 2.28E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_01730 5845326d16413209e4b4992adad168ff 301 Gene3D G3DSA:2.40.30.30 183 301 2.8E-37 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 THERU_01730 5845326d16413209e4b4992adad168ff 301 Pfam PF06574 FAD synthetase 11 163 6.5E-50 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THERU_01730 5845326d16413209e4b4992adad168ff 301 SMART SM00904 180 300 3.4E-50 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 THERU_01730 5845326d16413209e4b4992adad168ff 301 PIRSF PIRSF004491 1 301 8.1E-104 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THERU_01730 5845326d16413209e4b4992adad168ff 301 Gene3D G3DSA:3.40.50.620 3 182 6.3E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01730 5845326d16413209e4b4992adad168ff 301 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 16 297 6.5E-75 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THERU_01730 5845326d16413209e4b4992adad168ff 301 Pfam PF01687 Riboflavin kinase 181 297 3.6E-34 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 THERU_01730 5845326d16413209e4b4992adad168ff 301 SUPERFAMILY SSF82114 171 300 3.05E-38 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 THERU_01730 5845326d16413209e4b4992adad168ff 301 SUPERFAMILY SSF52374 15 178 3.56E-33 T 12-10-2018 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00690 Adhesin family signature 61 78 1.0E-7 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00690 Adhesin family signature 48 61 1.0E-7 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00690 Adhesin family signature 17 35 1.0E-7 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 SUPERFAMILY SSF53807 9 289 7.85E-61 T 12-10-2018 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00691 Adhesin B signature 17 38 1.0E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00691 Adhesin B signature 42 60 1.0E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 PRINTS PR00691 Adhesin B signature 61 80 1.0E-7 T 12-10-2018 IPR006129 Adhesin B GO:0007155 THERU_03540 9276fc5a378c99c29416619745597941 290 Gene3D G3DSA:3.40.50.1980 186 290 1.6E-8 T 12-10-2018 THERU_03540 9276fc5a378c99c29416619745597941 290 Pfam PF01297 Zinc-uptake complex component A periplasmic 20 288 1.8E-35 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THERU_03540 9276fc5a378c99c29416619745597941 290 Gene3D G3DSA:3.40.50.1980 12 170 1.7E-32 T 12-10-2018 THERU_00830 ca236f012878bb54a3286f3329084c2d 258 Pfam PF00510 Cytochrome c oxidase subunit III 12 253 3.3E-20 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00830 ca236f012878bb54a3286f3329084c2d 258 SUPERFAMILY SSF81452 3 253 2.49E-45 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_00830 ca236f012878bb54a3286f3329084c2d 258 Gene3D G3DSA:1.20.120.80 73 254 8.4E-39 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_07780 910bb7e69637d55f8c8fd6f078b7d02c 254 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_07780 910bb7e69637d55f8c8fd6f078b7d02c 254 SUPERFAMILY SSF52540 2 233 1.46E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07780 910bb7e69637d55f8c8fd6f078b7d02c 254 SMART SM00382 29 219 1.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_07780 910bb7e69637d55f8c8fd6f078b7d02c 254 Gene3D G3DSA:3.40.50.300 2 252 1.0E-73 T 12-10-2018 THERU_07780 910bb7e69637d55f8c8fd6f078b7d02c 254 Pfam PF00005 ABC transporter 20 170 2.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_05515 83e4273cec03644f55e024336b8ec40d 300 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 71 85 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site THERU_05515 83e4273cec03644f55e024336b8ec40d 300 SUPERFAMILY SSF48576 4 299 1.48E-76 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily THERU_05515 83e4273cec03644f55e024336b8ec40d 300 Pfam PF00348 Polyprenyl synthetase 21 244 1.3E-61 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 THERU_05515 83e4273cec03644f55e024336b8ec40d 300 Gene3D G3DSA:1.10.600.10 2 300 3.2E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 Pfam PF00444 Ribosomal protein L36 1 37 1.0E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.1E-24 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 9.0E-8 T 12-10-2018 THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.881 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01515 16d273ff2b75cd96579a92a5673fd53a 38 SUPERFAMILY SSF57840 1 37 3.14E-17 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_03280 a1be389abb48130c731880a99b22e0f5 292 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 66 88 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site THERU_03280 a1be389abb48130c731880a99b22e0f5 292 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 291 19.501 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 THERU_03280 a1be389abb48130c731880a99b22e0f5 292 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 13 289 6.1E-97 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 THERU_03280 a1be389abb48130c731880a99b22e0f5 292 Pfam PF01040 UbiA prenyltransferase family 27 273 4.1E-61 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THERU_03280 a1be389abb48130c731880a99b22e0f5 292 Gene3D G3DSA:1.10.357.140 18 179 1.8E-20 T 12-10-2018 THERU_04170 6523227516609b09c9c2a0337427135d 93 Gene3D G3DSA:4.10.520.10 1 93 3.2E-21 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_04170 6523227516609b09c9c2a0337427135d 93 SMART SM00411 1 90 4.1E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_04170 6523227516609b09c9c2a0337427135d 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.4E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_04170 6523227516609b09c9c2a0337427135d 93 SUPERFAMILY SSF47729 1 91 1.77E-21 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 Gene3D G3DSA:3.40.50.11740 64 308 7.3E-101 T 12-10-2018 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 Gene3D G3DSA:3.40.50.11750 21 268 7.3E-101 T 12-10-2018 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 Gene3D G3DSA:1.10.10.2140 323 374 4.7E-25 T 12-10-2018 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 PIRSF PIRSF005622 3 374 6.3E-152 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 373 4.1E-140 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THERU_04800 61a8cc2db1d3a1102f32d1c4b2bef188 374 Pfam PF01924 Hydrogenase formation hypA family 18 372 6.3E-146 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THERU_00735 6e454ba6c105177d2923c622c9d6475d 123 Gene3D G3DSA:3.30.160.170 20 119 1.1E-14 T 12-10-2018 IPR035924 FlaG-like superfamily THERU_00735 6e454ba6c105177d2923c622c9d6475d 123 Pfam PF03646 FlaG protein 31 120 4.0E-23 T 12-10-2018 IPR005186 FlaG protein THERU_00735 6e454ba6c105177d2923c622c9d6475d 123 SUPERFAMILY SSF160214 17 123 2.35E-24 T 12-10-2018 IPR035924 FlaG-like superfamily THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Gene3D G3DSA:1.25.40.10 357 435 8.4E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF13432 Tetratricopeptide repeat 193 249 0.016 T 12-10-2018 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SUPERFAMILY SSF48452 438 525 9.49E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Gene3D G3DSA:1.25.40.10 262 356 6.1E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Gene3D G3DSA:1.25.40.10 436 542 3.0E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF13181 Tetratricopeptide repeat 156 184 9.8E-7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF13181 Tetratricopeptide repeat 391 423 0.023 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF14559 Tetratricopeptide repeat 99 153 1.4E-8 T 12-10-2018 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF14559 Tetratricopeptide repeat 300 365 1.0E-11 T 12-10-2018 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SUPERFAMILY SSF48452 30 253 2.85E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 444 520 3.1E-9 T 12-10-2018 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 390 423 0.0031 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 85 118 430.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 288 321 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 187 220 6.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 424 460 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 322 355 1.3E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 461 494 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 153 186 5.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 221 254 6.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 356 389 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SMART SM00028 495 528 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 SUPERFAMILY SSF48452 263 428 5.31E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06230 cd31b78f4492cc353a4e8627085369df 545 Gene3D G3DSA:1.25.40.10 21 261 8.6E-39 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 Pfam PF02261 Aspartate decarboxylase 1 114 3.4E-47 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 1.0E-40 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 PIRSF PIRSF006246 1 125 7.3E-49 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 63.15 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 Gene3D G3DSA:2.40.40.20 1 125 2.9E-50 T 12-10-2018 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 90 3.0E-32 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THERU_00310 8c514b6d0a0a069252350b5041efabef 126 SUPERFAMILY SSF50692 1 117 5.84E-45 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THERU_01800 3c7e0c85b05996c3322d54bc88de7bb1 150 Pfam PF06557 Protein of unknown function (DUF1122) 24 149 1.3E-39 T 12-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 THERU_01800 3c7e0c85b05996c3322d54bc88de7bb1 150 Gene3D G3DSA:3.40.630.30 1 150 7.2E-54 T 12-10-2018 THERU_01800 3c7e0c85b05996c3322d54bc88de7bb1 150 SUPERFAMILY SSF55729 4 149 7.31E-48 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 Gene3D G3DSA:3.30.450.90 2 102 2.3E-28 T 12-10-2018 THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 349 8.4E-133 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 Gene3D G3DSA:3.40.50.300 103 362 3.2E-90 T 12-10-2018 THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 Pfam PF00437 Type II/IV secretion system protein 35 273 5.5E-43 T 12-10-2018 IPR001482 Type II/IV secretion system protein THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 SUPERFAMILY SSF52540 5 343 6.32E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00560 4ba4a4ce620f30603e7cb3b37048441a 366 SMART SM00382 126 254 2.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_01575 a60613448f7be41d12549d044368084a 337 Gene3D G3DSA:1.10.150.530 1 54 2.1E-18 T 12-10-2018 THERU_01575 a60613448f7be41d12549d044368084a 337 Pfam PF13394 4Fe-4S single cluster domain 100 186 1.7E-6 T 12-10-2018 THERU_01575 a60613448f7be41d12549d044368084a 337 Pfam PF04055 Radical SAM superfamily 96 260 3.9E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_01575 a60613448f7be41d12549d044368084a 337 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 1 335 65.788 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 THERU_01575 a60613448f7be41d12549d044368084a 337 Gene3D G3DSA:3.20.20.70 57 320 2.6E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_01575 a60613448f7be41d12549d044368084a 337 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 333 2.1E-117 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 THERU_01575 a60613448f7be41d12549d044368084a 337 SUPERFAMILY SSF102114 90 308 1.7E-13 T 12-10-2018 THERU_01575 a60613448f7be41d12549d044368084a 337 PIRSF PIRSF006004 1 335 2.3E-123 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 THERU_02045 c831b4aa004f427d241c224cac70b4a4 241 Pfam PF00460 Flagella basal body rod protein 8 38 2.4E-8 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THERU_02045 c831b4aa004f427d241c224cac70b4a4 241 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 7 133 1.4E-33 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G THERU_02045 c831b4aa004f427d241c224cac70b4a4 241 SUPERFAMILY SSF117143 90 201 7.19E-19 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like THERU_02045 c831b4aa004f427d241c224cac70b4a4 241 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site THERU_02045 c831b4aa004f427d241c224cac70b4a4 241 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 174 238 8.2E-14 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THERU_04340 861272df9e245050051bf8e20dfc52e1 269 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 4 150 2.3E-18 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THERU_04340 861272df9e245050051bf8e20dfc52e1 269 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 8 156 8.2E-13 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THERU_06235 ce5080d1039c153380d34edd612568b0 293 SUPERFAMILY SSF52402 1 145 8.29E-28 T 12-10-2018 THERU_06235 ce5080d1039c153380d34edd612568b0 293 Pfam PF00582 Universal stress protein family 150 287 3.9E-24 T 12-10-2018 IPR006016 UspA THERU_06235 ce5080d1039c153380d34edd612568b0 293 Pfam PF00582 Universal stress protein family 2 143 1.8E-22 T 12-10-2018 IPR006016 UspA THERU_06235 ce5080d1039c153380d34edd612568b0 293 Gene3D G3DSA:3.40.50.620 149 289 2.1E-30 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_06235 ce5080d1039c153380d34edd612568b0 293 PRINTS PR01438 Universal stress protein signature 249 261 5.2E-14 T 12-10-2018 IPR006015 Universal stress protein A THERU_06235 ce5080d1039c153380d34edd612568b0 293 PRINTS PR01438 Universal stress protein signature 150 168 5.2E-14 T 12-10-2018 IPR006015 Universal stress protein A THERU_06235 ce5080d1039c153380d34edd612568b0 293 PRINTS PR01438 Universal stress protein signature 267 289 5.2E-14 T 12-10-2018 IPR006015 Universal stress protein A THERU_06235 ce5080d1039c153380d34edd612568b0 293 SUPERFAMILY SSF52402 150 289 4.69E-30 T 12-10-2018 THERU_06235 ce5080d1039c153380d34edd612568b0 293 Gene3D G3DSA:3.40.50.620 1 148 1.9E-27 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 187 2.9E-62 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 PIRSF PIRSF500134 1 436 1.3E-175 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 420 1.2E-31 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 PIRSF PIRSF000124 1 435 1.6E-141 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 416 8.9E-140 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 293 1.8E-35 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Gene3D G3DSA:3.40.50.720 1 198 6.3E-77 T 12-10-2018 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 SUPERFAMILY SSF51735 1 193 4.07E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 SMART SM00984 316 420 3.8E-45 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Gene3D G3DSA:1.20.5.100 201 231 2.0E-15 T 12-10-2018 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 Gene3D G3DSA:3.40.50.720 232 436 2.2E-72 T 12-10-2018 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 SUPERFAMILY SSF48179 201 294 1.87E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_02450 0af56a6e3500de73e0ee78e20ec8b76d 436 SUPERFAMILY SSF52413 303 431 2.35E-35 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 THERU_02110 d7461cbd20ebca757e21be7d76985090 307 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 3 304 24.876 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THERU_02110 d7461cbd20ebca757e21be7d76985090 307 SUPERFAMILY SSF52540 30 157 3.94E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02110 d7461cbd20ebca757e21be7d76985090 307 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 7 293 4.1E-76 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THERU_02110 d7461cbd20ebca757e21be7d76985090 307 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 11 291 3.4E-69 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THERU_06435 64f31aa29ae6b82d3a198017a11dfb32 289 Pfam PF13489 Methyltransferase domain 87 228 2.6E-26 T 12-10-2018 THERU_06435 64f31aa29ae6b82d3a198017a11dfb32 289 Gene3D G3DSA:3.40.50.150 64 262 6.1E-36 T 12-10-2018 THERU_06435 64f31aa29ae6b82d3a198017a11dfb32 289 SUPERFAMILY SSF53335 75 246 1.78E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_04400 b3785be167388b5ddfdc6061f5163267 62 SUPERFAMILY SSF158568 2 44 3.4E-5 T 12-10-2018 IPR023101 AF1862-like domain superfamily THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PIRSF PIRSF005419 3 678 1.7E-238 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 7 675 2.4E-261 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 Gene3D G3DSA:3.40.30.60 346 489 1.3E-52 T 12-10-2018 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 Gene3D G3DSA:1.10.8.540 490 579 1.2E-22 T 12-10-2018 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 131 154 - T 12-10-2018 IPR025505 FHIPEP conserved site THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 126 142 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 226 240 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 145 163 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 175 192 8.9E-52 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 Gene3D G3DSA:1.10.490.80 580 675 7.4E-15 T 12-10-2018 THERU_08320 fa0e43a5c7737dbb3acdfd5a8615ee54 678 Pfam PF00771 FHIPEP family 15 667 9.0E-247 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THERU_07475 b0312a2e6536df4b87fdd199441c7c6f 152 Pfam PF03602 Conserved hypothetical protein 95 7 146 2.7E-24 T 12-10-2018 THERU_07475 b0312a2e6536df4b87fdd199441c7c6f 152 SUPERFAMILY SSF53335 9 148 4.64E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07475 b0312a2e6536df4b87fdd199441c7c6f 152 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 93 99 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THERU_07475 b0312a2e6536df4b87fdd199441c7c6f 152 Gene3D G3DSA:3.40.50.150 3 152 6.5E-35 T 12-10-2018 THERU_07475 b0312a2e6536df4b87fdd199441c7c6f 152 PIRSF PIRSF004553 1 150 3.0E-26 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 THERU_05610 72b7272953651ff6285f0621016d8ca6 255 SUPERFAMILY SSF52833 38 186 3.64E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_05610 72b7272953651ff6285f0621016d8ca6 255 Gene3D G3DSA:3.40.30.10 36 201 6.3E-27 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 Gene3D G3DSA:3.90.25.10 179 308 5.7E-104 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 305 8.4E-62 T 12-10-2018 IPR016040 NAD(P)-binding domain THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 SUPERFAMILY SSF51735 1 317 1.69E-97 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 PRINTS PR01713 Nucleotide sugar epimerase signature 275 292 3.2E-24 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 PRINTS PR01713 Nucleotide sugar epimerase signature 236 251 3.2E-24 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 3.2E-24 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 PRINTS PR01713 Nucleotide sugar epimerase signature 215 230 3.2E-24 T 12-10-2018 THERU_00590 3a263ec4df429901c974e13b82be7fcb 321 Gene3D G3DSA:3.40.50.720 4 296 5.7E-104 T 12-10-2018 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 7.0E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 7.0E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 7.0E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 7.0E-30 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 490 38.227 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 SUPERFAMILY SSF47323 340 489 1.2E-25 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 313 6.5E-132 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 SUPERFAMILY SSF52374 3 313 3.75E-104 T 12-10-2018 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 SMART SM00840 353 425 0.0039 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 Pfam PF09190 DALR domain 353 419 1.6E-9 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 488 1.3E-167 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 Gene3D G3DSA:1.20.120.640 307 490 6.0E-31 T 12-10-2018 THERU_05655 905b83fd5151dfb3417e97985079f9a7 491 Gene3D G3DSA:3.40.50.620 1 305 5.8E-135 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 470 1.4E-135 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 Gene3D G3DSA:1.20.210.10 6 528 2.2E-195 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 SUPERFAMILY SSF81442 15 521 3.14E-173 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 133 145 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 115 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_05620 07aeae77476c348d443b0dc974c9ae54 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 4.5E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Hamap MF_00900 GTPase HflX [hflX]. 21 370 44.213 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 PIRSF PIRSF006809 1 369 3.0E-133 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 SUPERFAMILY SSF52540 196 364 5.85E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Pfam PF01926 50S ribosome-binding GTPase 197 316 7.6E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Gene3D G3DSA:3.40.50.300 196 366 5.9E-41 T 12-10-2018 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 219 237 5.7E-10 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 198 218 5.7E-10 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 265 283 5.7E-10 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Pfam PF16360 GTP-binding GTPase Middle Region 108 186 3.7E-26 T 12-10-2018 IPR032305 GTP-binding protein, middle domain THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Pfam PF13167 GTP-binding GTPase N-terminal 19 105 3.2E-29 T 12-10-2018 IPR025121 GTPase HflX, N-terminal THERU_03335 c0b7571162cafb715a67dfb809db9544 370 Gene3D G3DSA:3.40.50.11060 10 132 8.8E-37 T 12-10-2018 THERU_03335 c0b7571162cafb715a67dfb809db9544 370 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 3 361 2.4E-127 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 THERU_08315 c46afd71ae240be43a15664faca29661 162 SMART SM00506 2 130 1.5E-48 T 12-10-2018 IPR002589 Macro domain THERU_08315 c46afd71ae240be43a15664faca29661 162 Pfam PF01661 Macro domain 19 130 2.0E-30 T 12-10-2018 IPR002589 Macro domain THERU_08315 c46afd71ae240be43a15664faca29661 162 SUPERFAMILY SSF52949 1 160 3.03E-49 T 12-10-2018 THERU_08315 c46afd71ae240be43a15664faca29661 162 Gene3D G3DSA:3.40.220.10 1 162 1.4E-51 T 12-10-2018 THERU_05290 55033e63845d9b250841750d5ce10279 163 Pfam PF14559 Tetratricopeptide repeat 116 157 8.5E-6 T 12-10-2018 THERU_05290 55033e63845d9b250841750d5ce10279 163 SUPERFAMILY SSF48452 21 142 2.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05290 55033e63845d9b250841750d5ce10279 163 Gene3D G3DSA:1.25.40.10 86 162 3.0E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_06995 9767151bda602c0c0171cf724de90563 206 Gene3D G3DSA:3.40.109.10 1 205 5.1E-55 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THERU_06995 9767151bda602c0c0171cf724de90563 206 Pfam PF00881 Nitroreductase family 8 183 8.7E-35 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THERU_06995 9767151bda602c0c0171cf724de90563 206 SUPERFAMILY SSF55469 1 205 1.06E-50 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SMART SM00028 524 557 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SMART SM00028 42 75 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SMART SM00028 191 224 86.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SMART SM00028 228 261 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SUPERFAMILY SSF48452 456 566 2.73E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 Gene3D G3DSA:1.25.40.10 35 341 1.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 Pfam PF13432 Tetratricopeptide repeat 198 245 0.0017 T 12-10-2018 THERU_03365 072f0d363d578cea86177de61e4f7892 605 SUPERFAMILY SSF48452 194 306 6.64E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03365 072f0d363d578cea86177de61e4f7892 605 Gene3D G3DSA:1.25.40.10 450 593 1.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05695 d86f88625405e5bbce64a26a76666a41 275 Gene3D G3DSA:1.10.4030.30 52 269 5.8E-21 T 12-10-2018 THERU_05695 d86f88625405e5bbce64a26a76666a41 275 Gene3D G3DSA:3.10.50.40 143 230 5.8E-21 T 12-10-2018 THERU_05695 d86f88625405e5bbce64a26a76666a41 275 SUPERFAMILY SSF109998 17 171 2.59E-15 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily THERU_05695 d86f88625405e5bbce64a26a76666a41 275 Pfam PF13145 PPIC-type PPIASE domain 125 240 1.1E-10 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 THERU_05695 d86f88625405e5bbce64a26a76666a41 275 SUPERFAMILY SSF54534 154 229 9.81E-8 T 12-10-2018 THERU_05695 d86f88625405e5bbce64a26a76666a41 275 Pfam PF13624 SurA N-terminal domain 2 92 3.3E-9 T 12-10-2018 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 SUPERFAMILY SSF51713 1 371 1.07E-151 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 Pfam PF01702 Queuine tRNA-ribosyltransferase 137 366 4.4E-88 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 371 55.076 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 4 373 8.1E-152 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 Gene3D G3DSA:3.20.20.105 1 375 5.8E-166 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_03360 c33e582f8bea5619616f8d55900bf8d7 377 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 372 1.9E-147 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 3 65 1.3E-16 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 SUPERFAMILY SSF63562 4 70 8.02E-16 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 Pfam PF01192 RNA polymerase Rpb6 11 65 2.2E-11 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 67 11.707 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 SMART SM01409 9 66 3.0E-10 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THERU_01155 25ef04d8879ee1f910c5a94e67193b90 73 Gene3D G3DSA:3.90.940.10 2 73 7.6E-14 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 SUPERFAMILY SSF54862 80 217 1.88E-30 T 12-10-2018 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 Gene3D G3DSA:3.10.20.740 4 125 3.0E-37 T 12-10-2018 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 Pfam PF00037 4Fe-4S binding domain 190 209 9.6E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 Gene3D G3DSA:3.30.70.20 131 212 1.0E-17 T 12-10-2018 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 SMART SM00929 86 126 7.8E-11 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 79 3.8E-19 T 12-10-2018 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 123 2.2E-11 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 SUPERFAMILY SSF53706 221 552 2.21E-24 T 12-10-2018 THERU_04590 fb1298fa89ae30f2426e9cdc8771a970 630 SUPERFAMILY SSF54292 5 118 9.96E-31 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THERU_03880 ccdaf4a15482fab377bbfae5bfabb9ae 149 Gene3D G3DSA:1.20.58.130 46 110 2.0E-5 T 12-10-2018 THERU_05065 90a4605317772b451da0183d3ead3cf1 245 SUPERFAMILY SSF52540 1 242 5.1E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05065 90a4605317772b451da0183d3ead3cf1 245 Gene3D G3DSA:3.40.50.300 1 242 4.4E-55 T 12-10-2018 THERU_05065 90a4605317772b451da0183d3ead3cf1 245 Pfam PF13614 AAA domain 1 165 1.9E-45 T 12-10-2018 IPR025669 AAA domain THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 414 1.2E-21 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Gene3D G3DSA:3.30.70.1050 1 116 5.5E-23 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Gene3D G3DSA:1.10.3120.10 117 419 3.7E-52 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Hamap MF_00303 Trigger factor [tig]. 1 420 16.871 T 12-10-2018 IPR005215 Trigger factor GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 TIGRFAM TIGR00115 tig: trigger factor 14 413 1.0E-82 T 12-10-2018 IPR005215 Trigger factor GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Gene3D G3DSA:3.10.50.40 153 245 3.7E-52 T 12-10-2018 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 SUPERFAMILY SSF102735 1 134 3.53E-24 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 SUPERFAMILY SSF54534 136 245 3.93E-11 T 12-10-2018 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 Pfam PF05697 Bacterial trigger factor protein (TF) 1 147 3.8E-27 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 SUPERFAMILY SSF109998 247 429 2.94E-32 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily THERU_05705 fcf3f6bdcc1dfd0653b0ab2c24221fee 434 PIRSF PIRSF003095 1 434 3.6E-84 T 12-10-2018 IPR005215 Trigger factor GO:0015031 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 SUPERFAMILY SSF52374 1 156 1.55E-38 T 12-10-2018 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 2.7E-38 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.7E-38 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.7E-38 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.7E-38 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 4.6E-58 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 31.465 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 Gene3D G3DSA:3.40.50.620 3 159 7.4E-49 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 Pfam PF01467 Cytidylyltransferase-like 5 133 2.7E-22 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_07480 fb90c204cea926a0022a95416cfbd7a2 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 56 8.3E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 Gene3D G3DSA:1.10.340.30 19 136 2.9E-30 T 12-10-2018 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 Gene3D G3DSA:1.10.1670.10 137 216 5.9E-10 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 Pfam PF00633 Helix-hairpin-helix motif 113 135 9.1E-8 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 PIRSF PIRSF001435 1 217 1.1E-62 T 12-10-2018 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 173 2.6E-16 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 SUPERFAMILY SSF48150 7 212 2.04E-47 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 SMART SM00278 116 135 0.0011 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THERU_06710 600ccc2c282179c8ab430c8351b86899 217 SMART SM00478 45 193 1.8E-31 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 SMART SM00419 177 225 2.8E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 Gene3D G3DSA:2.60.120.10 5 152 1.4E-29 T 12-10-2018 IPR014710 RmlC-like jelly roll fold THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 Pfam PF13545 Crp-like helix-turn-helix domain 158 232 5.0E-18 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 Gene3D G3DSA:1.10.10.10 155 234 4.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 199 5.5E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 199 214 5.5E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 Pfam PF00027 Cyclic nucleotide-binding domain 37 123 2.8E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 SUPERFAMILY SSF46785 156 233 3.61E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 SMART SM00100 19 138 1.5E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain THERU_08420 d5a0613f48f7ea531c6a5172ec07cf9f 234 SUPERFAMILY SSF51206 13 148 1.83E-29 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like THERU_00215 7774b92031ebc5ed920a417e4c0f6596 335 SMART SM00729 60 265 2.8E-13 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_00215 7774b92031ebc5ed920a417e4c0f6596 335 Gene3D G3DSA:3.20.20.70 59 321 7.2E-19 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_00215 7774b92031ebc5ed920a417e4c0f6596 335 Pfam PF04055 Radical SAM superfamily 66 212 1.6E-10 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_00215 7774b92031ebc5ed920a417e4c0f6596 335 SUPERFAMILY SSF102114 51 303 4.32E-30 T 12-10-2018 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 Pfam PF00515 Tetratricopeptide repeat 41 74 8.1E-9 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 SMART SM00028 8 41 0.0016 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 SMART SM00028 111 144 0.0071 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 SMART SM00028 42 74 7.7E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 SMART SM00028 75 108 10.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 Gene3D G3DSA:1.25.40.10 1 159 5.2E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 Pfam PF13424 Tetratricopeptide repeat 78 142 6.1E-9 T 12-10-2018 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 SUPERFAMILY SSF48452 7 148 2.73E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04685 8c1026d0b0ae97d28da9061ca2c5f7cb 159 Pfam PF07719 Tetratricopeptide repeat 8 40 6.8E-7 T 12-10-2018 IPR013105 Tetratricopeptide repeat 2 THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 3 222 4.8E-58 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 Pfam PF01168 Alanine racemase, N-terminal domain 36 222 6.7E-20 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 Gene3D G3DSA:3.20.20.10 1 223 2.1E-82 T 12-10-2018 IPR029066 PLP-binding barrel THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 4 223 29.485 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 SUPERFAMILY SSF51419 3 222 1.18E-74 T 12-10-2018 IPR029066 PLP-binding barrel THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THERU_06950 12d12757fcd38acba68a9727cc766e9b 223 PIRSF PIRSF004848 2 223 1.8E-74 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 186 6.7E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 16 185 9.2E-57 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 Gene3D G3DSA:3.40.50.300 8 188 3.5E-51 T 12-10-2018 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 Pfam PF01926 50S ribosome-binding GTPase 25 143 7.2E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 187 24.929 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THERU_07575 b94491d8952afe14f6e7c9b54a29a6ef 188 SUPERFAMILY SSF52540 20 185 5.22E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_07905 ae264874e983677f1c8ac0dd2e80d556 320 SUPERFAMILY SSF56112 20 279 3.57E-13 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily THERU_03650 c2fc3f705b25e4cca0d5898e058e27b2 283 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 283 2.7E-51 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 THERU_03650 c2fc3f705b25e4cca0d5898e058e27b2 283 Pfam PF08340 Domain of unknown function (DUF1732) 201 283 1.5E-27 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 THERU_03650 c2fc3f705b25e4cca0d5898e058e27b2 283 Pfam PF03755 YicC-like family, N-terminal region 1 151 9.7E-30 T 12-10-2018 IPR013527 YicC-like, N-terminal THERU_06875 43f6162288aefe10e1df833ae401b9b0 381 SUPERFAMILY SSF111249 2 362 4.97E-173 T 12-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THERU_06875 43f6162288aefe10e1df833ae401b9b0 381 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 361 0.0 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THERU_06875 43f6162288aefe10e1df833ae401b9b0 381 PIRSF PIRSF015647 1 372 1.9E-185 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THERU_06875 43f6162288aefe10e1df833ae401b9b0 381 Pfam PF01950 Fructose-1,6-bisphosphatase 2 361 7.2E-183 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THERU_06875 43f6162288aefe10e1df833ae401b9b0 381 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 362 59.222 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 82 106 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 105 4.6E-36 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 1.8E-37 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 SUPERFAMILY SSF54843 1 111 2.49E-43 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 26.819 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07360 0f50993bdc8e491238d1b06099e9bdac 113 Gene3D G3DSA:3.90.470.10 1 113 1.5E-43 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 Gene3D G3DSA:3.10.20.30 2 97 1.2E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_02145 235d61dc953f78628fb434c54eb495c9 233 Gene3D G3DSA:1.10.1060.10 99 224 8.9E-24 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 209 6.4E-51 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 Pfam PF13183 4Fe-4S dicluster domain 132 203 3.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_02145 235d61dc953f78628fb434c54eb495c9 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02145 235d61dc953f78628fb434c54eb495c9 233 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 49 57 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 SUPERFAMILY SSF54292 11 96 3.93E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 SUPERFAMILY SSF46548 106 211 1.45E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_02145 235d61dc953f78628fb434c54eb495c9 233 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 13 99 1.7E-25 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THERU_08340 9b1a786be1108b6406c0b288c0202e68 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 359 2.9E-110 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_08340 9b1a786be1108b6406c0b288c0202e68 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 357 23.59 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_08340 9b1a786be1108b6406c0b288c0202e68 359 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_08340 9b1a786be1108b6406c0b288c0202e68 359 Pfam PF00953 Glycosyl transferase family 4 101 282 8.6E-36 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 THERU_04855 89fb52dc5ce63a959afaf948e70af0dc 637 SUPERFAMILY SSF56762 1 612 2.09E-143 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04855 89fb52dc5ce63a959afaf948e70af0dc 637 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 603 612 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THERU_04855 89fb52dc5ce63a959afaf948e70af0dc 637 Gene3D G3DSA:1.10.645.10 1 612 4.5E-222 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04855 89fb52dc5ce63a959afaf948e70af0dc 637 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 40 65 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THERU_04855 89fb52dc5ce63a959afaf948e70af0dc 637 Pfam PF00374 Nickel-dependent hydrogenase 40 612 6.5E-193 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THERU_03300 42bf2f95dfb817a39b8cf63f692ac325 286 Gene3D G3DSA:3.40.50.970 117 283 2.9E-34 T 12-10-2018 THERU_03300 42bf2f95dfb817a39b8cf63f692ac325 286 SUPERFAMILY SSF52518 42 260 1.1E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_03300 42bf2f95dfb817a39b8cf63f692ac325 286 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 89 235 5.1E-24 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 SMART SM00487 249 423 1.5E-10 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Pfam PF00176 SNF2 family N-terminal domain 339 526 6.2E-10 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Pfam PF13091 PLD-like domain 19 192 1.0E-11 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 SMART SM00490 729 817 1.3E-17 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Gene3D G3DSA:3.40.50.300 630 837 2.9E-34 T 12-10-2018 THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Gene3D G3DSA:3.30.870.10 1 199 2.3E-19 T 12-10-2018 THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 SUPERFAMILY SSF52540 225 426 9.34E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 SUPERFAMILY SSF52540 347 868 4.06E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Gene3D G3DSA:3.40.50.10810 250 501 2.0E-21 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily THERU_03920 37bdb2d538ea65104638f7c98be54c4f 1098 Pfam PF00271 Helicase conserved C-terminal domain 707 817 7.0E-21 T 12-10-2018 IPR001650 Helicase, C-terminal THERU_08155 c4581818db44717218efebfd2ad586be 369 Gene3D G3DSA:1.10.10.1330 68 196 2.1E-35 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily THERU_08155 c4581818db44717218efebfd2ad586be 369 Pfam PF04552 Sigma-54, DNA binding domain 236 369 3.4E-32 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding THERU_08155 c4581818db44717218efebfd2ad586be 369 PRINTS PR00045 Sigma-54 factor signature 354 369 2.2E-16 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THERU_08155 c4581818db44717218efebfd2ad586be 369 PRINTS PR00045 Sigma-54 factor signature 303 314 2.2E-16 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THERU_08155 c4581818db44717218efebfd2ad586be 369 PRINTS PR00045 Sigma-54 factor signature 135 152 2.2E-16 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THERU_08155 c4581818db44717218efebfd2ad586be 369 PRINTS PR00045 Sigma-54 factor signature 287 299 2.2E-16 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THERU_08155 c4581818db44717218efebfd2ad586be 369 Pfam PF04963 Sigma-54 factor, core binding domain 70 189 7.4E-15 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 THERU_08155 c4581818db44717218efebfd2ad586be 369 Gene3D G3DSA:1.10.10.60 323 369 6.4E-10 T 12-10-2018 THERU_03410 711c4c6a2d6011e90192c10310b83fba 139 Gene3D G3DSA:3.40.50.300 2 137 2.9E-33 T 12-10-2018 THERU_03410 711c4c6a2d6011e90192c10310b83fba 139 SUPERFAMILY SSF52540 14 106 3.64E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03410 711c4c6a2d6011e90192c10310b83fba 139 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 107 4.3E-31 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THERU_03410 711c4c6a2d6011e90192c10310b83fba 139 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 6 105 1.7E-30 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THERU_07490 35c1a00da558682f87cbb03753f5b3d4 134 SUPERFAMILY SSF50685 25 117 5.58E-9 T 12-10-2018 IPR036908 RlpA-like domain superfamily THERU_07490 35c1a00da558682f87cbb03753f5b3d4 134 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 11 115 20.86 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THERU_07490 35c1a00da558682f87cbb03753f5b3d4 134 Gene3D G3DSA:2.40.40.10 23 115 7.1E-35 T 12-10-2018 IPR036908 RlpA-like domain superfamily THERU_07490 35c1a00da558682f87cbb03753f5b3d4 134 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 25 117 1.7E-38 T 12-10-2018 IPR012997 Rare lipoprotein A THERU_07490 35c1a00da558682f87cbb03753f5b3d4 134 Pfam PF03330 Lytic transglycolase 24 112 1.7E-22 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THERU_03225 6182e18ac796b7af38fa656034c4662a 176 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 69 82 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 THERU_03225 6182e18ac796b7af38fa656034c4662a 176 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 4 147 1.6E-42 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_03225 6182e18ac796b7af38fa656034c4662a 176 Pfam PF00994 Probable molybdopterin binding domain 7 150 2.8E-34 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_03225 6182e18ac796b7af38fa656034c4662a 176 SMART SM00852 7 153 2.7E-29 T 12-10-2018 IPR001453 MoaB/Mog domain THERU_03225 6182e18ac796b7af38fa656034c4662a 176 Gene3D G3DSA:3.40.980.10 1 176 3.8E-64 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily THERU_03225 6182e18ac796b7af38fa656034c4662a 176 SUPERFAMILY SSF53218 4 173 2.36E-48 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily THERU_03630 1c90d137dc49099856579803d3a7ec72 206 Gene3D G3DSA:3.40.50.620 1 205 1.4E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_03630 1c90d137dc49099856579803d3a7ec72 206 SUPERFAMILY SSF52402 1 203 3.7E-25 T 12-10-2018 THERU_03630 1c90d137dc49099856579803d3a7ec72 206 Pfam PF06508 Queuosine biosynthesis protein QueC 3 202 1.8E-26 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 Pfam PF13394 4Fe-4S single cluster domain 114 187 1.1E-5 T 12-10-2018 THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 PIRSF PIRSF004911 1 361 2.7E-144 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 SUPERFAMILY SSF102114 98 349 6.28E-38 T 12-10-2018 THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 325 9.0E-92 T 12-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 Pfam PF04055 Radical SAM superfamily 111 266 7.6E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 Pfam PF12544 Lysine-2,3-aminomutase 305 357 2.2E-13 T 12-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain THERU_04775 ca10298b0e5eea9cfb91a8592aae7511 362 Gene3D G3DSA:3.20.20.70 46 331 3.3E-112 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_06490 fb079d336035b637f83ce0e899e1872e 221 Pfam PF02108 Flagellar assembly protein FliH 93 211 2.2E-18 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE THERU_00255 ca9e6778aa9198b78e8e91309ff356e0 305 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 3 300 1.9E-117 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 THERU_00255 ca9e6778aa9198b78e8e91309ff356e0 305 Pfam PF03741 Integral membrane protein TerC family 68 270 8.8E-52 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 SUPERFAMILY SSF75217 56 214 1.31E-32 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 Gene3D G3DSA:2.40.240.20 1 51 1.2E-5 T 12-10-2018 THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 PIRSF PIRSF015601 1 217 2.2E-39 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 Gene3D G3DSA:3.40.1280.10 53 215 9.1E-45 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 Pfam PF04452 RNA methyltransferase 2 213 7.9E-44 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THERU_00440 da7b72bcf5356ee73e7a170d11028af9 219 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 1 214 3.4E-46 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 642 745 7.0E-11 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 639 658 1.9E-13 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 699 717 1.9E-13 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 669 688 1.9E-13 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 57 76 1.9E-13 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 558 574 1.9E-13 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 SUPERFAMILY SSF54211 556 750 3.68E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 Gene3D G3DSA:3.30.230.10 533 770 1.9E-95 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 Pfam PF13654 AAA domain 21 532 9.5E-159 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 Gene3D G3DSA:3.40.50.300 6 188 1.1E-20 T 12-10-2018 THERU_01085 7a3391d67345ee592e5a6beb4d033def 779 Gene3D G3DSA:3.40.50.300 206 446 1.8E-53 T 12-10-2018 THERU_04915 914a5b0b2f8e1c71a29167a7b29dcd69 152 Pfam PF07849 Protein of unknown function (DUF1641) 110 143 1.4E-14 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 THERU_01640 e085486296a213f9e316da7c91d425d9 371 Gene3D G3DSA:3.40.50.620 7 250 4.7E-38 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01640 e085486296a213f9e316da7c91d425d9 371 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 24 237 9.5E-17 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 THERU_01640 e085486296a213f9e316da7c91d425d9 371 SUPERFAMILY SSF52402 8 201 1.72E-26 T 12-10-2018 THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 Pfam PF00448 SRP54-type protein, GTPase domain 178 365 5.2E-43 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 Gene3D G3DSA:1.20.120.1380 120 357 3.6E-57 T 12-10-2018 THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 SMART SM00962 177 367 5.6E-46 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 SMART SM00382 176 330 7.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 Gene3D G3DSA:3.40.50.300 171 355 3.6E-57 T 12-10-2018 THERU_08325 6cd3f28b85b6990eb5521e7e5b972489 370 SUPERFAMILY SSF52540 178 367 9.23E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 SMART SM00825 Beta-ketoacyl synthase 5 410 3.3E-15 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 Gene3D G3DSA:3.40.47.10 1 256 2.5E-95 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 411 2.4E-199 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 370 2.0E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 248 6.0E-63 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 SUPERFAMILY SSF53901 216 412 1.48E-71 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 PIRSF PIRSF000447 1 413 4.1E-192 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 SUPERFAMILY SSF53901 3 253 7.96E-79 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_06145 d94650ec55ae3b93999b6bc2edfe7243 413 Gene3D G3DSA:3.40.47.10 258 402 1.3E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 217 282 2.5E-10 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 SUPERFAMILY SSF51905 3 315 1.13E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 Gene3D G3DSA:3.50.50.60 2 376 8.3E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-21 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 221 237 2.0E-21 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.0E-21 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 2.0E-21 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 SUPERFAMILY SSF55424 299 403 2.57E-5 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 270 6.8E-24 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 6.8E-24 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 6.8E-24 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 222 236 6.8E-24 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 318 6.8E-24 T 12-10-2018 THERU_04645 bdfc2939504b532d2b90f9b967b1ad4f 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 216 2.4E-26 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 Gene3D G3DSA:3.40.50.700 1 194 1.1E-52 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 PIRSF PIRSF000310 1 322 5.6E-87 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 Gene3D G3DSA:4.10.480.10 195 273 1.0E-19 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 197 269 9.6E-21 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 SUPERFAMILY SSF56770 3 269 5.23E-73 T 12-10-2018 THERU_04925 0d1b2d1fa664fa03ceaffec30fba60c5 323 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 175 6.2E-31 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02615 3a257e2e2f616fe0adbe4947cf42ee81 172 Gene3D G3DSA:2.60.40.200 23 172 3.4E-55 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 THERU_02615 3a257e2e2f616fe0adbe4947cf42ee81 172 SUPERFAMILY SSF49329 26 171 5.5E-44 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 THERU_02615 3a257e2e2f616fe0adbe4947cf42ee81 172 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 33 170 7.5E-41 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 THERU_02615 3a257e2e2f616fe0adbe4947cf42ee81 172 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 159 170 - T 12-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 THERU_06000 5feb02dcc14b35d7e72db16c022cd625 97 Pfam PF04930 FUN14 family 11 94 5.2E-11 T 12-10-2018 IPR007014 FUN14 THERU_06250 152f6331d34ffa1c138e88025093d949 144 Pfam PF00572 Ribosomal protein L13 14 138 9.0E-56 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THERU_06250 152f6331d34ffa1c138e88025093d949 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.095 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THERU_06250 152f6331d34ffa1c138e88025093d949 144 SUPERFAMILY SSF52161 1 139 1.7E-55 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_06250 152f6331d34ffa1c138e88025093d949 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 8 141 1.1E-61 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06250 152f6331d34ffa1c138e88025093d949 144 PIRSF PIRSF002181 1 144 1.1E-51 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THERU_06250 152f6331d34ffa1c138e88025093d949 144 Gene3D G3DSA:3.90.1180.10 1 142 7.4E-63 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_06250 152f6331d34ffa1c138e88025093d949 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 280 4.5E-25 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 Gene3D G3DSA:3.40.50.720 1 157 1.7E-40 T 12-10-2018 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 PIRSF PIRSF000103 1 284 1.9E-72 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 SUPERFAMILY SSF48179 159 283 4.99E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 Gene3D G3DSA:1.10.1040.10 158 284 2.8E-31 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 SUPERFAMILY SSF51735 1 160 5.58E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05485 adace91aeb1b6ae6b4352e50d199a8a0 284 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 158 7.3E-35 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Pfam PF00140 Sigma-70 factor, region 1.2 10 41 1.0E-11 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 299 7.7E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Pfam PF04539 Sigma-70 region 3 160 226 6.7E-12 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Gene3D G3DSA:1.10.10.10 228 310 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Gene3D G3DSA:1.20.120.1810 5 39 6.4E-5 T 12-10-2018 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Pfam PF04542 Sigma-70 region 2 46 113 5.0E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 SUPERFAMILY SSF88659 160 222 2.44E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Gene3D G3DSA:1.10.10.10 115 157 3.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_07970 f3b714725e7607703ba9019846be6f7d 311 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 270 296 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Gene3D G3DSA:1.20.120.1810 40 114 4.9E-31 T 12-10-2018 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 SUPERFAMILY SSF88659 208 307 1.51E-28 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Pfam PF04545 Sigma-70, region 4 246 298 3.0E-21 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 SUPERFAMILY SSF88659 115 154 1.31E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THERU_07970 f3b714725e7607703ba9019846be6f7d 311 SUPERFAMILY SSF88946 7 113 7.22E-39 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 Gene3D G3DSA:1.10.10.10 158 224 4.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_07970 f3b714725e7607703ba9019846be6f7d 311 PRINTS PR00046 Major sigma-70 factor signature 70 83 2.0E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 PRINTS PR00046 Major sigma-70 factor signature 270 285 2.0E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 PRINTS PR00046 Major sigma-70 factor signature 94 102 2.0E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 PRINTS PR00046 Major sigma-70 factor signature 285 296 2.0E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_07970 f3b714725e7607703ba9019846be6f7d 311 PRINTS PR00046 Major sigma-70 factor signature 249 261 2.0E-22 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 Gene3D G3DSA:3.20.20.70 31 276 3.2E-41 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 Pfam PF03537 Glycoside-hydrolase family GH114 58 264 1.6E-22 T 12-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 64 83 2.2E-5 T 12-10-2018 IPR016062 Hypothetical protein TM1410-related THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 225 235 2.2E-5 T 12-10-2018 IPR016062 Hypothetical protein TM1410-related THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 247 259 2.2E-5 T 12-10-2018 IPR016062 Hypothetical protein TM1410-related THERU_05935 ed6bfcf2d89890cffdbebd200525987a 898 SUPERFAMILY SSF51445 24 276 4.18E-41 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily THERU_04895 2173833aa83857b51a3517c8808d7e86 284 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 167 240 6.3E-24 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THERU_04895 2173833aa83857b51a3517c8808d7e86 284 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 11 148 2.9E-26 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04895 2173833aa83857b51a3517c8808d7e86 284 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 220 233 1.1E-9 T 12-10-2018 THERU_04895 2173833aa83857b51a3517c8808d7e86 284 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 73 87 1.1E-9 T 12-10-2018 THERU_04895 2173833aa83857b51a3517c8808d7e86 284 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 193 219 1.1E-9 T 12-10-2018 THERU_04895 2173833aa83857b51a3517c8808d7e86 284 PIRSF PIRSF000310 1 284 2.6E-72 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THERU_04895 2173833aa83857b51a3517c8808d7e86 284 Gene3D G3DSA:4.10.480.10 167 245 3.7E-21 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily THERU_04895 2173833aa83857b51a3517c8808d7e86 284 Gene3D G3DSA:3.40.50.700 1 166 4.3E-36 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily THERU_04895 2173833aa83857b51a3517c8808d7e86 284 SUPERFAMILY SSF56770 2 240 6.67E-63 T 12-10-2018 THERU_01770 f3a1d89cc334145b440b93e58cd2b84c 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 4 66 19.324 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THERU_01770 f3a1d89cc334145b440b93e58cd2b84c 67 Pfam PF02416 mttA/Hcf106 family 7 55 1.0E-20 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THERU_01770 f3a1d89cc334145b440b93e58cd2b84c 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 50 5.5E-21 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 4 372 8.7E-117 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 25 376 43.53 T 12-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 Pfam PF01747 ATP-sulfurylase 164 372 6.8E-86 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 Gene3D G3DSA:3.40.50.620 164 374 1.1E-89 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 SUPERFAMILY SSF88697 1 160 3.28E-45 T 12-10-2018 IPR015947 PUA-like superfamily THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 Pfam PF14306 PUA-like domain 3 155 7.4E-46 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 SUPERFAMILY SSF52374 165 374 3.64E-74 T 12-10-2018 THERU_04970 f8e8869026cc6ac25a53c27ccb81f0ae 384 Gene3D G3DSA:3.10.400.10 1 160 4.2E-43 T 12-10-2018 THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 201 35.403 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 Gene3D G3DSA:3.40.50.880 2 205 3.8E-75 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 Pfam PF00117 Glutamine amidotransferase class-I 6 197 9.3E-22 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 SUPERFAMILY SSF52317 2 199 5.73E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 PIRSF PIRSF000495 3 202 1.1E-69 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THERU_07915 176c19b9afd5dd780736b98165c9d14a 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 5 199 5.9E-72 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 193 209 3.0E-5 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Gene3D G3DSA:1.10.340.30 29 138 6.3E-69 T 12-10-2018 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 SMART SM00478 44 191 6.4E-62 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 PIRSF PIRSF001435 4 218 1.6E-49 T 12-10-2018 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 193 209 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 174 7.0E-25 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Pfam PF00633 Helix-hairpin-helix motif 105 132 2.1E-5 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Hamap MF_00942 Endonuclease III [nth]. 1 215 32.26 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 SUPERFAMILY SSF48150 7 212 5.18E-68 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 Gene3D G3DSA:1.10.1670.10 139 209 6.3E-69 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THERU_08485 fb5e54e4eaaa1069084ef1a4f6a91007 218 SMART SM00525 192 212 7.0E-7 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 Gene3D G3DSA:2.40.150.20 1 121 1.8E-48 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 121 24.371 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 Pfam PF00238 Ribosomal protein L14p/L23e 1 121 9.9E-48 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 ProSitePatterns PS00049 Ribosomal protein L14 signature. 59 85 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 121 9.8E-50 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 SUPERFAMILY SSF50193 1 121 1.96E-47 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 THERU_01445 4863a2d26f26e1c14ff303aa25a58c84 121 SMART SM01374 1 121 5.4E-72 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THERU_06965 d15cf075eac3ec1e6c8960b2e720cefa 247 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 244 1.7E-56 T 12-10-2018 IPR005226 UPF0014 family THERU_06965 d15cf075eac3ec1e6c8960b2e720cefa 247 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 246 3.8E-50 T 12-10-2018 IPR005226 UPF0014 family THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 436 1.7E-78 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 381 453 3.8E-21 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 Pfam PF00460 Flagella basal body rod protein 7 35 1.2E-5 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 SUPERFAMILY SSF117143 88 415 1.57E-53 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 Pfam PF07559 Flagellar basal body protein FlaE 187 339 6.7E-19 T 12-10-2018 IPR011491 Flagellar hook protein FlgE THERU_06850 6e34717e930a0a48ef509f5c66997b5e 455 Gene3D G3DSA:2.60.98.20 160 289 3.6E-22 T 12-10-2018 IPR037058 Flagellar hook protein FlgE superfamily THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 7.3E-6 T 12-10-2018 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 7.3E-6 T 12-10-2018 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.3E-6 T 12-10-2018 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 Gene3D G3DSA:3.50.50.60 115 274 1.0E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 325 4.0E-17 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 Gene3D G3DSA:3.50.50.60 5 325 1.0E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-5 T 12-10-2018 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 1.8E-5 T 12-10-2018 THERU_00175 395b1557205e7c6ab2ca481bdec5ddb7 352 SUPERFAMILY SSF51905 1 344 3.88E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_06830 862751fd5661c3d2338b9314fa95207b 758 PIRSF PIRSF000382 1 758 1.8E-297 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 754 32.789 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 317 1.8E-96 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 SUPERFAMILY SSF51726 5 374 6.41E-75 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 SUPERFAMILY SSF51726 392 754 5.36E-117 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 Gene3D G3DSA:3.20.20.210 7 520 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 427 749 2.0E-149 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 Gene3D G3DSA:3.20.20.210 387 752 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THERU_06830 862751fd5661c3d2338b9314fa95207b 758 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 753 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THERU_01355 7b44caa15b00f0ed53b1881270894f3a 395 Gene3D G3DSA:1.20.1530.20 4 395 4.7E-95 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily THERU_01355 7b44caa15b00f0ed53b1881270894f3a 395 Pfam PF00999 Sodium/hydrogen exchanger family 12 393 6.6E-76 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THERU_03970 ed6fa3af763ddd503383c403cea9eb94 244 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 61 243 7.3E-44 T 12-10-2018 THERU_03970 ed6fa3af763ddd503383c403cea9eb94 244 Gene3D G3DSA:3.40.50.150 64 243 1.3E-43 T 12-10-2018 THERU_03970 ed6fa3af763ddd503383c403cea9eb94 244 SUPERFAMILY SSF53335 59 239 2.37E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_05095 85ca46698fd733158009ef2ea4813155 455 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 17 440 5.7E-211 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_05095 85ca46698fd733158009ef2ea4813155 455 Pfam PF01964 Radical SAM ThiC family 17 437 2.2E-203 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_05095 85ca46698fd733158009ef2ea4813155 455 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 16 442 97.014 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_05095 85ca46698fd733158009ef2ea4813155 455 Gene3D G3DSA:3.20.20.540 59 373 1.9E-151 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 SUPERFAMILY SSF56784 380 627 1.7E-40 T 12-10-2018 IPR036412 HAD-like superfamily THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 148 689 1.9E-144 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 393 399 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 625 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 547 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 391 405 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 526 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 249 263 9.8E-26 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 Pfam PF00122 E1-E2 ATPase 204 370 7.4E-36 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 SUPERFAMILY SSF81653 204 298 7.45E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 171 666 2.2E-71 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 Gene3D G3DSA:3.40.50.1000 372 639 1.0E-81 T 12-10-2018 IPR023214 HAD superfamily THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 Gene3D G3DSA:2.70.150.20 192 302 1.0E-33 T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 Gene3D G3DSA:3.40.1110.10 402 522 1.0E-81 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 ProSitePatterns PS01229 Hypothetical cof family signature 2. 590 612 - T 12-10-2018 THERU_01980 98f0be076c2c45bd83804878ed3f5ca5 692 Pfam PF00702 haloacid dehalogenase-like hydrolase 388 604 5.8E-38 T 12-10-2018 THERU_00915 0715838bbac0b5493d1732a6cb6aebe4 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 5.5E-46 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THERU_00915 0715838bbac0b5493d1732a6cb6aebe4 304 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 3 304 3.4E-107 T 12-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 THERU_00915 0715838bbac0b5493d1732a6cb6aebe4 304 Gene3D G3DSA:3.90.25.10 169 298 3.6E-94 T 12-10-2018 THERU_00915 0715838bbac0b5493d1732a6cb6aebe4 304 SUPERFAMILY SSF51735 1 303 7.5E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_00915 0715838bbac0b5493d1732a6cb6aebe4 304 Gene3D G3DSA:3.40.50.720 3 288 3.6E-94 T 12-10-2018 THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 Pfam PF00155 Aminotransferase class I and II 22 363 1.6E-53 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 Gene3D G3DSA:3.40.640.10 1 368 1.2E-120 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 SUPERFAMILY SSF53383 4 367 5.59E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 83 103 1.1E-11 T 12-10-2018 THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 149 173 1.1E-11 T 12-10-2018 THERU_02745 a0e0d4cf6db82415015bdd9503b15674 368 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 185 208 1.1E-11 T 12-10-2018 THERU_08280 dc2027a3df5347951c6ba8396efd253a 155 Pfam PF03748 Flagellar basal body-associated protein FliL 58 153 3.4E-26 T 12-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 THERU_03605 160d3302b06fa8021986ccec679e880f 289 Gene3D G3DSA:3.40.1380.10 63 207 8.7E-89 T 12-10-2018 THERU_03605 160d3302b06fa8021986ccec679e880f 289 Pfam PF00231 ATP synthase 7 288 3.0E-87 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 Gene3D G3DSA:1.10.287.80 8 283 8.7E-89 T 12-10-2018 THERU_03605 160d3302b06fa8021986ccec679e880f 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 7 287 1.1E-86 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 3 288 31.007 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 PRINTS PR00126 ATP synthase gamma subunit signature 169 186 1.1E-24 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 1.1E-24 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 1.1E-24 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 1.1E-24 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_03605 160d3302b06fa8021986ccec679e880f 289 SUPERFAMILY SSF52943 5 288 7.59E-81 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 115 131 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 9 149 6.4E-71 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 SUPERFAMILY SSF56770 7 152 3.79E-64 T 12-10-2018 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 35 143 4.2E-23 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 Gene3D G3DSA:3.40.50.12280 1 168 3.4E-73 T 12-10-2018 THERU_05460 2a1ef7b4fed891c3a04ef7480687ebf5 178 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 2 148 41.287 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 215 7.2E-69 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 220 1.8E-69 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 1.3E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 149 177 1.3E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 1.3E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 1.3E-44 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00015 d5eb30fc16310f490248ae813ecb8e9d 245 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 234 17.138 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THERU_00020 f14b7e0cd8d5200ae6221827b9f8c0fb 283 Pfam PF02153 Prephenate dehydrogenase 26 273 2.1E-76 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 THERU_00020 f14b7e0cd8d5200ae6221827b9f8c0fb 283 Gene3D G3DSA:1.10.3660.10 175 282 6.1E-36 T 12-10-2018 THERU_00020 f14b7e0cd8d5200ae6221827b9f8c0fb 283 SUPERFAMILY SSF51735 4 168 2.15E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_00020 f14b7e0cd8d5200ae6221827b9f8c0fb 283 SUPERFAMILY SSF48179 172 279 4.31E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_00020 f14b7e0cd8d5200ae6221827b9f8c0fb 283 Gene3D G3DSA:3.40.50.720 2 174 3.4E-45 T 12-10-2018 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 257 41.227 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 PIRSF PIRSF000456 1 261 1.9E-99 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 SUPERFAMILY SSF51161 2 256 1.38E-72 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Gene3D G3DSA:2.160.10.10 1 191 1.1E-46 T 12-10-2018 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 148 176 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 138 2.0E-6 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 30 64 3.9E-7 T 12-10-2018 IPR001451 Hexapeptide repeat THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Gene3D G3DSA:1.20.1180.10 192 257 5.3E-25 T 12-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 255 8.0E-29 T 12-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 THERU_02650 242d1ebb5430bf2dee3188f7c96fc385 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 3 255 5.8E-100 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THERU_00905 1158387949e53054061ed4d70db0ba46 68 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 66 6.0E-19 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THERU_00905 1158387949e53054061ed4d70db0ba46 68 Pfam PF01809 Haemolytic domain 2 67 1.6E-29 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THERU_00905 1158387949e53054061ed4d70db0ba46 68 SMART SM01234 1 68 1.5E-41 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THERU_00905 1158387949e53054061ed4d70db0ba46 68 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 68 4.8E-29 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THERU_00905 1158387949e53054061ed4d70db0ba46 68 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 68 22.265 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THERU_06075 57c697656d0aa26e09a9be6e063a9c7a 278 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 2 266 46.552 T 12-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 THERU_06075 57c697656d0aa26e09a9be6e063a9c7a 278 Gene3D G3DSA:3.40.190.10 5 258 5.7E-106 T 12-10-2018 THERU_06075 57c697656d0aa26e09a9be6e063a9c7a 278 Pfam PF02621 Menaquinone biosynthesis 3 260 5.4E-91 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme THERU_06075 57c697656d0aa26e09a9be6e063a9c7a 278 SUPERFAMILY SSF53850 3 265 7.14E-92 T 12-10-2018 THERU_06075 57c697656d0aa26e09a9be6e063a9c7a 278 Gene3D G3DSA:3.40.190.10 80 172 5.7E-106 T 12-10-2018 THERU_04790 27fedd828eeafcc652e23e785284f402 122 Gene3D G3DSA:3.20.20.540 1 43 5.4E-17 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_04790 27fedd828eeafcc652e23e785284f402 122 Pfam PF01964 Radical SAM ThiC family 1 104 9.5E-44 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THERU_07390 8638a739751405867409c2080f31cdae 79 Gene3D G3DSA:3.40.1260.10 7 78 1.1E-7 T 12-10-2018 IPR027396 DsrEFH-like THERU_07390 8638a739751405867409c2080f31cdae 79 SUPERFAMILY SSF75169 14 79 5.15E-14 T 12-10-2018 IPR027396 DsrEFH-like THERU_00910 01e035b935b634f0155f9f6448933a35 501 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 308 485 1.7E-63 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00910 01e035b935b634f0155f9f6448933a35 501 Pfam PF02096 60Kd inner membrane protein 309 485 5.9E-57 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 9 487 17.243 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR00701 60kDa inner membrane protein signature 7 28 4.7E-30 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR00701 60kDa inner membrane protein signature 370 393 4.7E-30 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR00701 60kDa inner membrane protein signature 416 438 4.7E-30 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR00701 60kDa inner membrane protein signature 451 474 4.7E-30 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 Pfam PF14849 YidC periplasmic domain 261 297 2.6E-5 T 12-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR01900 YidC translocation/secretion protein signature 294 310 1.2E-13 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR01900 YidC translocation/secretion protein signature 440 464 1.2E-13 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_00910 01e035b935b634f0155f9f6448933a35 501 PRINTS PR01900 YidC translocation/secretion protein signature 422 437 1.2E-13 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THERU_07710 94ad9dc59657fc6349049f5896d695e1 120 Pfam PF06803 Protein of unknown function (DUF1232) 64 90 6.2E-8 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 THERU_03575 83eca008a98c866c2c8fc992308ad178 208 Gene3D G3DSA:3.20.20.70 4 204 2.1E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03575 83eca008a98c866c2c8fc992308ad178 208 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 5 205 36.245 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THERU_03575 83eca008a98c866c2c8fc992308ad178 208 SUPERFAMILY SSF51366 6 202 2.67E-57 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_03575 83eca008a98c866c2c8fc992308ad178 208 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 7 200 1.7E-45 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 8.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 8.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 8.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 SUPERFAMILY SSF52768 8 336 6.71E-93 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 Gene3D G3DSA:3.40.800.20 4 376 4.2E-122 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_00025 15cd651b3ebb2d7b5e624ef40a7bbf7c 378 Pfam PF00850 Histone deacetylase domain 24 312 6.3E-69 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THERU_05895 51604ec488ad31e6f1b796c4c762103d 409 Gene3D G3DSA:3.40.50.1100 62 380 4.2E-105 T 12-10-2018 THERU_05895 51604ec488ad31e6f1b796c4c762103d 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 375 1.6E-68 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THERU_05895 51604ec488ad31e6f1b796c4c762103d 409 Gene3D G3DSA:3.40.50.1100 108 204 4.2E-105 T 12-10-2018 THERU_05895 51604ec488ad31e6f1b796c4c762103d 409 TIGRFAM TIGR00260 thrC: threonine synthase 57 380 1.5E-86 T 12-10-2018 IPR004450 Threonine synthase-like THERU_05895 51604ec488ad31e6f1b796c4c762103d 409 SUPERFAMILY SSF53686 6 404 3.54E-91 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 PIRSF PIRSF039093 1 173 3.3E-79 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 Pfam PF00227 Proteasome subunit 2 169 3.2E-23 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 Gene3D G3DSA:3.60.20.10 1 173 2.1E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 38.606 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 SUPERFAMILY SSF56235 1 172 1.83E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THERU_05200 abc63a11592d3518a5512e1d8c9814b0 173 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 171 1.7E-77 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THERU_03760 a1326ff948c38c7cb4b72f9e61c62afd 250 Gene3D G3DSA:3.40.30.10 92 250 4.3E-30 T 12-10-2018 THERU_03760 a1326ff948c38c7cb4b72f9e61c62afd 250 SUPERFAMILY SSF52833 109 249 3.69E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_03760 a1326ff948c38c7cb4b72f9e61c62afd 250 Pfam PF13098 Thioredoxin-like domain 131 243 6.5E-16 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_03760 a1326ff948c38c7cb4b72f9e61c62afd 250 Pfam PF10411 Disulfide bond isomerase protein N-terminus 39 95 2.6E-14 T 12-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THERU_05875 f29d5d88348ccd72976e2e409338555a 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 231 1.8E-35 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THERU_05875 f29d5d88348ccd72976e2e409338555a 265 Gene3D G3DSA:3.40.50.1000 77 188 3.3E-56 T 12-10-2018 IPR023214 HAD superfamily THERU_05875 f29d5d88348ccd72976e2e409338555a 265 SUPERFAMILY SSF56784 4 256 8.53E-45 T 12-10-2018 IPR036412 HAD-like superfamily THERU_05875 f29d5d88348ccd72976e2e409338555a 265 Pfam PF13242 HAD-hyrolase-like 184 255 2.3E-16 T 12-10-2018 THERU_05875 f29d5d88348ccd72976e2e409338555a 265 Gene3D G3DSA:3.40.50.1000 5 254 3.3E-56 T 12-10-2018 IPR023214 HAD superfamily THERU_05875 f29d5d88348ccd72976e2e409338555a 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 107 5.7E-23 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THERU_05880 e4962f638993887bb66ed00de1b5add4 533 Gene3D G3DSA:3.40.50.20 1 104 5.2E-48 T 12-10-2018 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 SMART SM00851 413 499 6.3E-33 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain THERU_05880 e4962f638993887bb66ed00de1b5add4 533 SUPERFAMILY SSF56059 115 391 7.6E-100 T 12-10-2018 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 280 287 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 12 26 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 225 242 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 41 51 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 191 210 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 155 167 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 280 309 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 370 388 6.4E-37 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 Pfam PF02142 MGS-like domain 414 499 1.1E-21 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain THERU_05880 e4962f638993887bb66ed00de1b5add4 533 SUPERFAMILY SSF52440 2 117 4.89E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THERU_05880 e4962f638993887bb66ed00de1b5add4 533 SUPERFAMILY SSF52335 393 530 3.66E-40 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THERU_05880 e4962f638993887bb66ed00de1b5add4 533 Gene3D G3DSA:3.30.470.20 107 393 4.1E-109 T 12-10-2018 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 151 165 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 317 4.3E-37 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THERU_05880 e4962f638993887bb66ed00de1b5add4 533 Gene3D G3DSA:3.40.50.1380 394 532 2.9E-43 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THERU_02255 ed9d3862f06687112ffe06d573f00cc6 173 Hamap MF_00796 Nucleoside-triphosphatase . 1 172 23.055 T 12-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 THERU_02255 ed9d3862f06687112ffe06d573f00cc6 173 SMART SM00382 2 158 0.0019 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_02255 ed9d3862f06687112ffe06d573f00cc6 173 Pfam PF03266 NTPase 2 169 4.7E-48 T 12-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 THERU_02255 ed9d3862f06687112ffe06d573f00cc6 173 Gene3D G3DSA:3.40.50.300 1 173 5.0E-63 T 12-10-2018 THERU_02255 ed9d3862f06687112ffe06d573f00cc6 173 SUPERFAMILY SSF52540 2 168 8.68E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 SMART SM01091 329 408 1.6E-21 T 12-10-2018 IPR005170 Transporter-associated domain THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 SUPERFAMILY SSF54631 187 318 1.71E-24 T 12-10-2018 THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 Pfam PF03471 Transporter associated domain 331 404 2.3E-18 T 12-10-2018 IPR005170 Transporter-associated domain THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 SUPERFAMILY SSF56176 327 409 1.12E-19 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 Gene3D G3DSA:3.10.580.10 180 327 2.8E-37 T 12-10-2018 THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 Gene3D G3DSA:3.30.465.10 336 406 2.7E-18 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 Pfam PF00571 CBS domain 268 317 1.5E-6 T 12-10-2018 IPR000644 CBS domain THERU_02350 b0ca6017aeaa44d0c39199ea6042fed4 412 Pfam PF01595 Domain of unknown function DUF21 13 167 4.4E-33 T 12-10-2018 IPR002550 CNNM, transmembrane domain THERU_03955 bda306c3012e7d8f881019141dd3ae6f 146 Pfam PF14437 MafB19-like deaminase 3 146 7.5E-33 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THERU_03955 bda306c3012e7d8f881019141dd3ae6f 146 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 88 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THERU_03955 bda306c3012e7d8f881019141dd3ae6f 146 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 6 146 37.852 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THERU_03955 bda306c3012e7d8f881019141dd3ae6f 146 SUPERFAMILY SSF53927 4 143 3.68E-44 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THERU_03955 bda306c3012e7d8f881019141dd3ae6f 146 Gene3D G3DSA:3.40.140.10 1 146 2.6E-55 T 12-10-2018 THERU_03150 7c9c57266a302fbcff1ced25d710ba52 295 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 12 276 2.8E-87 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 THERU_03150 7c9c57266a302fbcff1ced25d710ba52 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 273 5.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_03150 7c9c57266a302fbcff1ced25d710ba52 295 SUPERFAMILY SSF161098 29 270 2.75E-30 T 12-10-2018 IPR035906 MetI-like superfamily THERU_03150 7c9c57266a302fbcff1ced25d710ba52 295 Gene3D G3DSA:1.10.3720.10 61 276 3.2E-28 T 12-10-2018 IPR035906 MetI-like superfamily THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 347 1.4E-76 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 268 1.7E-25 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 Gene3D G3DSA:1.10.287.470 90 160 3.2E-64 T 12-10-2018 THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 SUPERFAMILY SSF111369 46 273 7.59E-35 T 12-10-2018 THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 Gene3D G3DSA:2.40.30.170 41 275 3.2E-64 T 12-10-2018 THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 Gene3D G3DSA:2.40.50.100 56 202 3.2E-64 T 12-10-2018 THERU_00485 1428376a7f04da9f5c1d30b5ed813ecb 349 Gene3D G3DSA:2.40.420.20 34 345 3.2E-64 T 12-10-2018 THERU_05835 7660910dbc9ac3e3581cf07e12205f98 113 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 6 110 7.1E-39 T 12-10-2018 IPR018685 Protein of unknown function DUF2173 THERU_05835 7660910dbc9ac3e3581cf07e12205f98 113 PIRSF PIRSF006821 1 113 5.6E-51 T 12-10-2018 IPR018685 Protein of unknown function DUF2173 THERU_00335 0f81852dcba468aecb596db80cce8141 108 SUPERFAMILY SSF52833 3 107 7.21E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_00335 0f81852dcba468aecb596db80cce8141 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.5E-10 T 12-10-2018 THERU_00335 0f81852dcba468aecb596db80cce8141 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.5E-10 T 12-10-2018 THERU_00335 0f81852dcba468aecb596db80cce8141 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.5E-10 T 12-10-2018 THERU_00335 0f81852dcba468aecb596db80cce8141 108 Gene3D G3DSA:3.40.30.10 4 108 2.9E-39 T 12-10-2018 THERU_00335 0f81852dcba468aecb596db80cce8141 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 6.7E-42 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THERU_00335 0f81852dcba468aecb596db80cce8141 108 PIRSF PIRSF000077 2 108 3.4E-43 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THERU_00335 0f81852dcba468aecb596db80cce8141 108 Pfam PF00085 Thioredoxin 5 104 1.3E-34 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 THERU_00335 0f81852dcba468aecb596db80cce8141 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THERU_03020 670e0fab8fdbfea5438cfc9eb1af61d1 219 SUPERFAMILY SSF53597 1 215 2.52E-54 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THERU_03020 670e0fab8fdbfea5438cfc9eb1af61d1 219 Pfam PF01872 RibD C-terminal domain 3 210 2.9E-56 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THERU_03020 670e0fab8fdbfea5438cfc9eb1af61d1 219 Gene3D G3DSA:3.40.430.10 1 218 7.8E-58 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THERU_03020 670e0fab8fdbfea5438cfc9eb1af61d1 219 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 1 211 2.6E-53 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 THERU_02960 dc6688a1ea3e23d371e2437b0858bcc1 360 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 5 319 9.4E-85 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 THERU_02960 dc6688a1ea3e23d371e2437b0858bcc1 360 SMART SM00729 2 214 1.2E-52 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_02960 dc6688a1ea3e23d371e2437b0858bcc1 360 Pfam PF04055 Radical SAM superfamily 7 168 5.6E-23 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02960 dc6688a1ea3e23d371e2437b0858bcc1 360 Gene3D G3DSA:3.80.30.20 3 292 2.6E-91 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THERU_02960 dc6688a1ea3e23d371e2437b0858bcc1 360 SUPERFAMILY SSF102114 4 354 1.28E-100 T 12-10-2018 THERU_02260 84696f7f4176ca27053bafd682348d2d 261 SUPERFAMILY SSF52343 83 222 1.07E-9 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THERU_02260 84696f7f4176ca27053bafd682348d2d 261 Gene3D G3DSA:2.40.30.10 1 86 8.9E-11 T 12-10-2018 THERU_02260 84696f7f4176ca27053bafd682348d2d 261 SUPERFAMILY SSF63380 2 88 1.45E-9 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THERU_02260 84696f7f4176ca27053bafd682348d2d 261 PIRSF PIRSF006816 1 229 1.8E-28 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 THERU_02260 84696f7f4176ca27053bafd682348d2d 261 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 186 223 2.2E-11 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain THERU_06915 ae15e0932a4ce5f8aa6d94e786ba33ca 174 Gene3D G3DSA:3.40.50.2020 1 174 1.5E-63 T 12-10-2018 THERU_06915 ae15e0932a4ce5f8aa6d94e786ba33ca 174 Pfam PF00156 Phosphoribosyl transferase domain 16 159 3.2E-28 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THERU_06915 ae15e0932a4ce5f8aa6d94e786ba33ca 174 SUPERFAMILY SSF53271 4 173 2.75E-53 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_06915 ae15e0932a4ce5f8aa6d94e786ba33ca 174 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 11 173 1.9E-65 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 THERU_00845 9b67227b405a04b25870f039ce384571 578 Gene3D G3DSA:3.55.50.30 20 112 4.1E-8 T 12-10-2018 THERU_00845 9b67227b405a04b25870f039ce384571 578 Gene3D G3DSA:3.30.1370.120 154 229 1.8E-7 T 12-10-2018 IPR038591 NolW-like superfamily THERU_00845 9b67227b405a04b25870f039ce384571 578 Pfam PF00263 Bacterial type II and III secretion system protein 419 577 3.5E-42 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 THERU_00845 9b67227b405a04b25870f039ce384571 578 Gene3D G3DSA:3.30.1370.120 237 326 4.3E-5 T 12-10-2018 IPR038591 NolW-like superfamily THERU_00845 9b67227b405a04b25870f039ce384571 578 PRINTS PR00811 Bacterial general secretion pathway protein D signature 564 578 1.0E-10 T 12-10-2018 IPR001775 GspD/PilQ family THERU_00845 9b67227b405a04b25870f039ce384571 578 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 459 1.0E-10 T 12-10-2018 IPR001775 GspD/PilQ family THERU_00845 9b67227b405a04b25870f039ce384571 578 PRINTS PR00811 Bacterial general secretion pathway protein D signature 334 344 1.0E-10 T 12-10-2018 IPR001775 GspD/PilQ family THERU_00845 9b67227b405a04b25870f039ce384571 578 PRINTS PR00811 Bacterial general secretion pathway protein D signature 414 438 1.0E-10 T 12-10-2018 IPR001775 GspD/PilQ family THERU_00845 9b67227b405a04b25870f039ce384571 578 PRINTS PR00811 Bacterial general secretion pathway protein D signature 541 559 1.0E-10 T 12-10-2018 IPR001775 GspD/PilQ family THERU_06560 f06898b2c72f720f15fa7947205cf18f 593 Gene3D G3DSA:3.30.750.24 422 558 1.0E-21 T 12-10-2018 IPR036513 STAS domain superfamily THERU_06560 f06898b2c72f720f15fa7947205cf18f 593 Pfam PF01740 STAS domain 446 550 1.4E-18 T 12-10-2018 IPR002645 STAS domain THERU_06560 f06898b2c72f720f15fa7947205cf18f 593 Pfam PF00916 Sulfate permease family 24 389 6.3E-100 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THERU_06560 f06898b2c72f720f15fa7947205cf18f 593 TIGRFAM TIGR00815 sulP: sulfate permease 11 550 1.9E-131 T 12-10-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 THERU_06560 f06898b2c72f720f15fa7947205cf18f 593 SUPERFAMILY SSF52091 445 555 9.81E-16 T 12-10-2018 IPR036513 STAS domain superfamily THERU_04815 be4c231d896f988ac5baae84c99ea418 251 Gene3D G3DSA:3.40.50.300 1 249 4.8E-67 T 12-10-2018 THERU_04815 be4c231d896f988ac5baae84c99ea418 251 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_04815 be4c231d896f988ac5baae84c99ea418 251 SUPERFAMILY SSF52540 1 229 3.59E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04815 be4c231d896f988ac5baae84c99ea418 251 SMART SM00382 26 214 8.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_04815 be4c231d896f988ac5baae84c99ea418 251 Pfam PF00005 ABC transporter 17 169 5.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 Pfam PF00701 Dihydrodipicolinate synthetase family 2 287 1.1E-101 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 Gene3D G3DSA:3.20.20.70 1 294 3.9E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 SMART SM01130 1 289 7.5E-145 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 PIRSF PIRSF001365 1 294 4.2E-96 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 SUPERFAMILY SSF51569 2 289 1.26E-103 T 12-10-2018 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 8.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 8.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 8.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 8.6E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 132 163 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 3.2E-127 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_05410 94478a2cbf1bc05254fb15b6efc44e74 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 67.858 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THERU_05170 26ad69eea446b1d3b76b61bc506d7f25 256 Pfam PF07282 Putative transposase DNA-binding domain 128 195 6.0E-20 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_05170 26ad69eea446b1d3b76b61bc506d7f25 256 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 85 153 9.9E-7 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_01010 c8dd8f50bb672026601ad1c5d43cea07 187 Gene3D G3DSA:3.40.50.10490 1 187 3.8E-73 T 12-10-2018 THERU_01010 c8dd8f50bb672026601ad1c5d43cea07 187 SUPERFAMILY SSF53697 1 186 7.42E-56 T 12-10-2018 THERU_01010 c8dd8f50bb672026601ad1c5d43cea07 187 Pfam PF13580 SIS domain 13 144 5.7E-31 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THERU_01010 c8dd8f50bb672026601ad1c5d43cea07 187 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 187 38.219 T 12-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 THERU_04840 bf239a1871d06c893c30505cbf2f4792 228 Pfam PF10670 Domain of unknown function (DUF4198) 17 206 8.9E-19 T 12-10-2018 IPR019613 Protein of unknown function DUF4198 THERU_08495 6869a9026ee3cdafa2a588dd5266cbfd 100 Pfam PF02635 DsrE/DsrF-like family 1 99 1.9E-6 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THERU_08495 6869a9026ee3cdafa2a588dd5266cbfd 100 Gene3D G3DSA:3.40.1260.10 1 99 1.3E-7 T 12-10-2018 IPR027396 DsrEFH-like THERU_08495 6869a9026ee3cdafa2a588dd5266cbfd 100 SUPERFAMILY SSF75169 1 99 4.37E-10 T 12-10-2018 IPR027396 DsrEFH-like THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 PIRSF PIRSF004846 2 250 3.1E-63 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 Gene3D G3DSA:3.40.190.10 102 208 1.5E-71 T 12-10-2018 THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 28 245 1.6E-55 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 Pfam PF13531 Bacterial extracellular solute-binding protein 23 246 3.1E-48 T 12-10-2018 THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 Gene3D G3DSA:3.40.190.10 27 246 1.5E-71 T 12-10-2018 THERU_03795 356dbc9e75655baddca0e5fbbda68632 253 SUPERFAMILY SSF53850 22 249 7.5E-62 T 12-10-2018 THERU_07225 aeddfa4bedb13832cd1a6bc9d8d28d79 177 SUPERFAMILY SSF50324 6 174 5.23E-70 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THERU_07225 aeddfa4bedb13832cd1a6bc9d8d28d79 177 Gene3D G3DSA:3.90.80.10 1 174 2.2E-74 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THERU_07225 aeddfa4bedb13832cd1a6bc9d8d28d79 177 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 65 71 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THERU_07225 aeddfa4bedb13832cd1a6bc9d8d28d79 177 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 39.171 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THERU_07225 aeddfa4bedb13832cd1a6bc9d8d28d79 177 Pfam PF00719 Inorganic pyrophosphatase 18 173 2.1E-60 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THERU_07495 82e3efc2008223a0684bdaafbbd4dbac 266 Pfam PF04055 Radical SAM superfamily 37 198 5.1E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_07495 82e3efc2008223a0684bdaafbbd4dbac 266 SMART SM00729 33 235 4.7E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_07495 82e3efc2008223a0684bdaafbbd4dbac 266 Gene3D G3DSA:3.20.20.70 6 250 5.0E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_07495 82e3efc2008223a0684bdaafbbd4dbac 266 SUPERFAMILY SSF102114 30 223 7.72E-24 T 12-10-2018 THERU_07495 82e3efc2008223a0684bdaafbbd4dbac 266 Pfam PF13394 4Fe-4S single cluster domain 42 118 5.6E-5 T 12-10-2018 THERU_02885 d02709a852dac78f268667e2fee24b98 224 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 215 4.9E-37 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_02885 d02709a852dac78f268667e2fee24b98 224 Gene3D G3DSA:3.20.20.70 2 223 8.9E-63 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02885 d02709a852dac78f268667e2fee24b98 224 SUPERFAMILY SSF51366 2 218 2.2E-52 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_02885 d02709a852dac78f268667e2fee24b98 224 SMART SM00934 3 216 8.6E-60 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_02885 d02709a852dac78f268667e2fee24b98 224 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 216 9.2E-45 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_02885 d02709a852dac78f268667e2fee24b98 224 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 54 67 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_02965 9669a3284140b42bd91d53b6543ed26d 354 Pfam PF01098 Cell cycle protein 2 344 5.4E-89 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_02965 9669a3284140b42bd91d53b6543ed26d 354 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 2 341 8.4E-108 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_02645 22c756c20a03fb312ab771b6c4f59166 223 Pfam PF02464 Competence-damaged protein 66 217 2.7E-56 T 12-10-2018 IPR008136 CinA, C-terminal THERU_02645 22c756c20a03fb312ab771b6c4f59166 223 SUPERFAMILY SSF142433 58 219 1.31E-56 T 12-10-2018 IPR036653 CinA-like, C-terminal THERU_02645 22c756c20a03fb312ab771b6c4f59166 223 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 71 216 8.9E-43 T 12-10-2018 IPR008136 CinA, C-terminal THERU_02645 22c756c20a03fb312ab771b6c4f59166 223 Gene3D G3DSA:3.90.950.20 51 219 3.8E-57 T 12-10-2018 IPR036653 CinA-like, C-terminal THERU_04625 8826c28d72671a6eca7c319e211636ca 167 Gene3D G3DSA:2.102.10.10 30 159 6.1E-40 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_04625 8826c28d72671a6eca7c319e211636ca 167 Pfam PF00355 Rieske [2Fe-2S] domain 62 127 1.6E-10 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THERU_04625 8826c28d72671a6eca7c319e211636ca 167 SUPERFAMILY SSF50022 34 155 3.64E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_04625 8826c28d72671a6eca7c319e211636ca 167 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 33 158 9.0E-62 T 12-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 THERU_01765 37feb79509a7919f947015cd8728fba8 313 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 1.9E-5 T 12-10-2018 THERU_01765 37feb79509a7919f947015cd8728fba8 313 PRINTS PR01713 Nucleotide sugar epimerase signature 211 226 1.9E-5 T 12-10-2018 THERU_01765 37feb79509a7919f947015cd8728fba8 313 PRINTS PR01713 Nucleotide sugar epimerase signature 273 290 1.9E-5 T 12-10-2018 THERU_01765 37feb79509a7919f947015cd8728fba8 313 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 2.4E-51 T 12-10-2018 IPR016040 NAD(P)-binding domain THERU_01765 37feb79509a7919f947015cd8728fba8 313 Gene3D G3DSA:3.40.50.720 1 312 2.2E-109 T 12-10-2018 THERU_01765 37feb79509a7919f947015cd8728fba8 313 SUPERFAMILY SSF51735 1 311 2.31E-92 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Gene3D G3DSA:1.10.10.160 106 168 1.8E-75 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Gene3D G3DSA:1.10.486.10 358 508 4.6E-84 T 12-10-2018 THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Pfam PF13361 UvrD-like helicase C-terminal domain 251 576 1.3E-66 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Gene3D G3DSA:3.40.50.300 255 589 4.6E-84 T 12-10-2018 THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Pfam PF13245 AAA domain 8 229 4.3E-32 T 12-10-2018 THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 SUPERFAMILY SSF52540 2 595 2.43E-142 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05600 96df8bf4859f7e670e499cd41f6e87ba 657 Gene3D G3DSA:3.40.50.300 4 246 1.8E-75 T 12-10-2018 THERU_05250 c87f736de3dfe8ddb5674ad36ca35550 217 Pfam PF02656 Domain of unknown function (DUF202) 16 81 1.4E-7 T 12-10-2018 IPR003807 Domain of unknown function DUF202 THERU_05250 c87f736de3dfe8ddb5674ad36ca35550 217 Pfam PF02656 Domain of unknown function (DUF202) 104 181 2.9E-18 T 12-10-2018 IPR003807 Domain of unknown function DUF202 THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 255 7.8E-120 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 Pfam PF00005 ABC transporter 27 180 4.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 SUPERFAMILY SSF52540 9 242 5.08E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 SMART SM00382 36 235 2.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 Gene3D G3DSA:3.40.50.300 10 253 2.1E-68 T 12-10-2018 THERU_03145 443ea758fca4fb16df499d5bdb370a3d 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_07840 c840fdf00ef353ee0d421b25743dcf87 438 Gene3D G3DSA:1.20.1600.10 18 438 1.3E-77 T 12-10-2018 THERU_07840 c840fdf00ef353ee0d421b25743dcf87 438 Pfam PF02321 Outer membrane efflux protein 249 430 2.3E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_07840 c840fdf00ef353ee0d421b25743dcf87 438 Pfam PF02321 Outer membrane efflux protein 22 227 1.3E-28 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_07840 c840fdf00ef353ee0d421b25743dcf87 438 SUPERFAMILY SSF56954 4 434 1.57E-72 T 12-10-2018 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Gene3D G3DSA:3.30.1370.10 241 340 1.8E-8 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Pfam PF12072 Domain of unknown function (DUF3552) 127 240 1.8E-17 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Pfam PF12072 Domain of unknown function (DUF3552) 7 127 1.4E-8 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Hamap MF_00335 Ribonuclease Y [rny]. 6 556 23.964 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 SMART SM00471 368 474 1.2E-11 T 12-10-2018 IPR003607 HD/PDEase domain THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 SMART SM00322 244 311 1.3E-10 T 12-10-2018 IPR004087 K Homology domain GO:0003676 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Pfam PF00013 KH domain 247 306 7.4E-7 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 SUPERFAMILY SSF109604 360 506 3.38E-28 T 12-10-2018 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 SUPERFAMILY SSF54791 242 339 3.32E-16 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Pfam PF01966 HD domain 374 464 1.7E-17 T 12-10-2018 IPR006674 HD domain THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 126 556 8.4E-186 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 Gene3D G3DSA:1.10.3210.10 361 508 5.5E-23 T 12-10-2018 THERU_08205 32b1ee1ab2737495ba025ca7a1c6654f 556 TIGRFAM TIGR00277 HDIG: HDIG domain 368 445 2.2E-23 T 12-10-2018 IPR006675 HDIG domain THERU_05885 e1248614c4b85a63403f4f0b7d3ef23b 437 Pfam PF01551 Peptidase family M23 324 418 1.3E-28 T 12-10-2018 IPR016047 Peptidase M23 THERU_05885 e1248614c4b85a63403f4f0b7d3ef23b 437 Gene3D G3DSA:2.70.70.10 267 424 2.4E-39 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_05885 e1248614c4b85a63403f4f0b7d3ef23b 437 SUPERFAMILY SSF51261 255 422 6.41E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_01840 67432ace4b5b37c01be5c5448cc9fd00 256 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 247 3.5E-82 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THERU_01840 67432ace4b5b37c01be5c5448cc9fd00 256 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 254 17.665 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THERU_01840 67432ace4b5b37c01be5c5448cc9fd00 256 Pfam PF02673 Bacitracin resistance protein BacA 6 248 1.3E-74 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 Pfam PF01022 Bacterial regulatory protein, arsR family 21 65 1.4E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 SMART SM00418 14 92 7.3E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 SUPERFAMILY SSF46785 3 92 4.48E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 8.6E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 8.6E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 8.6E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 8.6E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THERU_00340 432c1c0b2c53c7fe93a273a060c208e8 103 Gene3D G3DSA:1.10.10.10 1 99 1.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 Gene3D G3DSA:3.40.50.150 279 630 1.3E-69 T 12-10-2018 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 302 318 1.2E-23 T 12-10-2018 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 474 498 1.2E-23 T 12-10-2018 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 326 340 1.2E-23 T 12-10-2018 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 438 450 1.2E-23 T 12-10-2018 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 Pfam PF02384 N-6 DNA Methylase 284 574 1.3E-39 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 36 144 6.2E-24 T 12-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain THERU_01920 5fcbf65e8ee1dcb341a2ebaea0c34c07 796 SUPERFAMILY SSF53335 193 684 5.28E-78 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_01270 bed1feca2b52e03e6cdcaa8e3ae64194 284 Pfam PF03934 Type II secretion system (T2SS), protein K 32 277 4.7E-25 T 12-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THERU_01270 bed1feca2b52e03e6cdcaa8e3ae64194 284 Gene3D G3DSA:1.10.150.320 177 246 8.0E-11 T 12-10-2018 THERU_01270 bed1feca2b52e03e6cdcaa8e3ae64194 284 SUPERFAMILY SSF81585 180 250 2.16E-10 T 12-10-2018 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 28 252 31.019 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 Gene3D G3DSA:3.20.20.70 1 257 1.6E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 254 5.3E-82 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 SUPERFAMILY SSF51366 3 255 1.14E-77 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 256 33.058 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THERU_03840 60a985b666c97fe79a313b1ece80b3ac 259 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 49 67 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 THERU_07090 8eea02c39b34c0d293ad0aa17b7d53eb 522 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 269 341 1.2E-14 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_07090 8eea02c39b34c0d293ad0aa17b7d53eb 522 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 354 426 5.8E-6 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SUPERFAMILY SSF54106 23 68 4.71E-11 T 12-10-2018 THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SMART SM00257 24 68 3.3E-19 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SMART SM00257 199 243 7.2E-4 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SMART SM00257 140 184 3.7E-4 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SMART SM00257 80 123 1.9E-14 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SMART SM00257 257 301 0.019 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:3.10.350.10 256 301 3.6E-6 T 12-10-2018 IPR036779 LysM domain superfamily THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:3.10.350.10 131 190 1.6E-8 T 12-10-2018 IPR036779 LysM domain superfamily THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:3.10.350.10 74 130 1.5E-16 T 12-10-2018 IPR036779 LysM domain superfamily THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:3.10.350.10 191 253 2.8E-7 T 12-10-2018 IPR036779 LysM domain superfamily THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:3.10.350.10 16 73 1.3E-16 T 12-10-2018 IPR036779 LysM domain superfamily THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SUPERFAMILY SSF54106 256 301 1.03E-5 T 12-10-2018 THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SUPERFAMILY SSF54106 140 184 5.62E-6 T 12-10-2018 THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01476 LysM domain 200 243 0.018 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01476 LysM domain 81 123 1.2E-12 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01476 LysM domain 258 301 0.063 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01476 LysM domain 25 68 9.0E-13 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01476 LysM domain 141 184 0.0017 T 12-10-2018 IPR018392 LysM domain THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SUPERFAMILY SSF51261 341 454 2.35E-29 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Pfam PF01551 Peptidase family M23 356 450 2.3E-21 T 12-10-2018 IPR016047 Peptidase M23 THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 Gene3D G3DSA:2.70.70.10 303 458 1.6E-25 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_05335 e190d6d2823777a2b25b77ce4126213a 458 SUPERFAMILY SSF54106 79 123 1.83E-10 T 12-10-2018 THERU_03675 5d44baef494ab2a90177230351aee331 146 Hamap MF_01398 ATP synthase subunit b [atpF]. 6 144 11.232 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THERU_03675 5d44baef494ab2a90177230351aee331 146 Pfam PF00430 ATP synthase B/B' CF(0) 12 141 9.7E-19 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 Gene3D G3DSA:3.40.50.700 43 223 4.1E-66 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 211 228 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 185 208 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 113 136 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 156 180 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 281 294 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 247 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 44 66 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 67 91 7.8E-112 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 PIRSF PIRSF000310 2 354 2.0E-140 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 SUPERFAMILY SSF56770 44 308 9.71E-87 T 12-10-2018 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 224 305 1.8E-30 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 2 348 4.0E-151 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 59 204 2.7E-28 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04850 100c2d9f78d6ced18e058890e5377d99 354 Gene3D G3DSA:4.10.480.10 226 336 4.2E-44 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily THERU_02105 2633b612b9e002afb59a69404c16cbda 219 Pfam PF02254 TrkA-N domain 10 123 2.0E-25 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THERU_02105 2633b612b9e002afb59a69404c16cbda 219 SUPERFAMILY SSF116726 134 216 9.02E-20 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THERU_02105 2633b612b9e002afb59a69404c16cbda 219 Gene3D G3DSA:3.40.50.720 1 140 7.3E-35 T 12-10-2018 THERU_02105 2633b612b9e002afb59a69404c16cbda 219 Pfam PF02080 TrkA-C domain 162 217 4.6E-15 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THERU_02105 2633b612b9e002afb59a69404c16cbda 219 Gene3D G3DSA:3.30.70.1450 141 218 5.9E-23 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THERU_02105 2633b612b9e002afb59a69404c16cbda 219 SUPERFAMILY SSF51735 8 136 3.94E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03535 a3d369dcab93f84d1f11f9193f1abb6c 247 Pfam PF00950 ABC 3 transport family 2 148 9.7E-8 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THERU_03535 a3d369dcab93f84d1f11f9193f1abb6c 247 Pfam PF00950 ABC 3 transport family 154 237 3.1E-9 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THERU_03535 a3d369dcab93f84d1f11f9193f1abb6c 247 SUPERFAMILY SSF81345 14 237 1.15E-6 T 12-10-2018 IPR037294 ABC transporter, BtuC-like THERU_05865 a0ba8dec514525029186bf28dfa8cccd 263 Gene3D G3DSA:3.40.50.300 1 252 3.1E-72 T 12-10-2018 THERU_05865 a0ba8dec514525029186bf28dfa8cccd 263 PIRSF PIRSF003092 1 263 2.0E-81 T 12-10-2018 IPR025501 ATP binding protein MinD THERU_05865 a0ba8dec514525029186bf28dfa8cccd 263 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 220 5.2E-24 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THERU_05865 a0ba8dec514525029186bf28dfa8cccd 263 SUPERFAMILY SSF52540 1 253 1.16E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05865 a0ba8dec514525029186bf28dfa8cccd 263 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 259 2.0E-105 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 THERU_06480 e11621457cc64d2cda759c412ebf1d5c 160 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 22 3.0E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_06480 e11621457cc64d2cda759c412ebf1d5c 160 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 23 7.0E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_03720 bd9fbbdb3fabbaac2b55962b0c1ed157 98 Pfam PF06195 Protein of unknown function (DUF996) 41 91 3.3E-9 T 12-10-2018 IPR010397 Protein of unknown function DUF996 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 Gene3D G3DSA:3.30.360.10 156 422 2.4E-122 T 12-10-2018 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 169 439 1.7E-74 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 Gene3D G3DSA:3.40.50.720 7 394 2.4E-122 T 12-10-2018 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 166 2.2E-37 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 SUPERFAMILY SSF55347 156 440 4.9E-79 T 12-10-2018 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PIRSF PIRSF000110 1 441 4.3E-123 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 441 59.886 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 SUPERFAMILY SSF51735 4 168 1.65E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 122 135 7.5E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 198 215 7.5E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 216 232 7.5E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 146 174 7.5E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_06015 834d929eb31567db2b897a29a7c85c7e 441 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 285 311 7.5E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THERU_00315 de7cddb8f055b4ac20192464d9526957 166 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 163 4.0E-38 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THERU_00315 de7cddb8f055b4ac20192464d9526957 166 Gene3D G3DSA:3.30.479.10 1 166 1.0E-41 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THERU_00315 de7cddb8f055b4ac20192464d9526957 166 SUPERFAMILY SSF55620 3 163 1.83E-36 T 12-10-2018 THERU_03845 b6becc83d18bb99a5adcc5873b95a73d 195 Gene3D G3DSA:3.30.110.40 4 81 8.5E-26 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_03845 b6becc83d18bb99a5adcc5873b95a73d 195 Pfam PF01206 Sulfurtransferase TusA 10 79 6.9E-20 T 12-10-2018 IPR001455 TusA-like domain THERU_03845 b6becc83d18bb99a5adcc5873b95a73d 195 SUPERFAMILY SSF64307 8 79 2.22E-21 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_03845 b6becc83d18bb99a5adcc5873b95a73d 195 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 12-10-2018 IPR001455 TusA-like domain THERU_03845 b6becc83d18bb99a5adcc5873b95a73d 195 Pfam PF11823 Protein of unknown function (DUF3343) 120 184 9.3E-13 T 12-10-2018 IPR021778 Domain of unknown function DUF3343 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 Gene3D G3DSA:3.30.1330.50 1 155 1.0E-62 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 Pfam PF02542 YgbB family 2 153 2.5E-57 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 154 31.204 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 SUPERFAMILY SSF69765 1 154 4.19E-55 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_02755 898d7f9d6a5e1f3a9b9a05e39bf7bbca 155 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 153 1.6E-59 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THERU_07595 413ca9e86637a4adedeb78f8843ba1ff 147 SUPERFAMILY SSF57716 84 118 1.4E-7 T 12-10-2018 THERU_07595 413ca9e86637a4adedeb78f8843ba1ff 147 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 82 116 1.4E-8 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THERU_07595 413ca9e86637a4adedeb78f8843ba1ff 147 Gene3D G3DSA:1.20.120.910 1 120 3.3E-27 T 12-10-2018 THERU_07595 413ca9e86637a4adedeb78f8843ba1ff 147 SUPERFAMILY SSF109635 2 83 3.01E-11 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 Gene3D G3DSA:3.30.1490.10 80 136 9.7E-22 T 12-10-2018 THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 136 25.979 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 SUPERFAMILY SSF56047 1 136 5.23E-39 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 Pfam PF00410 Ribosomal protein S8 2 136 3.1E-48 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 Gene3D G3DSA:3.30.1370.30 1 79 1.7E-23 T 12-10-2018 THERU_01465 08048d17c5eb26021c76a2680895c9e7 136 ProSitePatterns PS00053 Ribosomal protein S8 signature. 106 123 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 Gene3D G3DSA:3.40.50.150 58 275 1.8E-67 T 12-10-2018 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 Pfam PF01564 Spermine/spermidine synthase domain 60 239 1.9E-66 T 12-10-2018 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 Pfam PF17284 Spermidine synthase tetramerisation domain 5 57 5.2E-19 T 12-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 TIGRFAM TIGR00417 speE: spermidine synthase 20 265 5.2E-92 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 275 38.316 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 SUPERFAMILY SSF53335 13 274 3.78E-82 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_05400 bb3ff8996b1f7f90e0c0a49de34538ac 280 Gene3D G3DSA:2.30.140.10 1 57 3.5E-16 T 12-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 147 23.359 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 141 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 SUPERFAMILY SSF52080 5 147 2.09E-49 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.4E-55 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 Gene3D G3DSA:3.100.10.10 70 148 4.4E-28 T 12-10-2018 THERU_01490 4c654215e1b6bbdb5fe08b28d7b1534e 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 145 1.6E-40 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P THERU_04145 0b7674df66386bf2a8483060dfcc7058 227 Gene3D G3DSA:2.40.10.220 98 219 7.0E-7 T 12-10-2018 THERU_01050 ae690bbf75c533b0b6318be8d864813b 166 Pfam PF13098 Thioredoxin-like domain 40 157 2.3E-15 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_01050 ae690bbf75c533b0b6318be8d864813b 166 Gene3D G3DSA:3.40.30.10 35 163 1.7E-26 T 12-10-2018 THERU_01050 ae690bbf75c533b0b6318be8d864813b 166 SUPERFAMILY SSF52833 21 156 1.17E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_03085 727474161dbc77fdf8ca5feabe00f8f2 545 Pfam PF05140 ResB-like family 81 528 4.5E-99 T 12-10-2018 IPR007816 ResB-like domain THERU_02100 20841c3fb99109a8c4976a94ee070f63 430 Pfam PF02386 Cation transport protein 23 411 4.1E-57 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 THERU_02100 20841c3fb99109a8c4976a94ee070f63 430 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 15 402 1.6E-109 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 THERU_00555 84225c41ddd0aa33a809669b18cbff08 214 Hamap MF_00238 Cytidylate kinase [cmk]. 1 214 29.861 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THERU_00555 84225c41ddd0aa33a809669b18cbff08 214 SUPERFAMILY SSF52540 1 214 1.63E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00555 84225c41ddd0aa33a809669b18cbff08 214 Pfam PF02224 Cytidylate kinase 3 212 3.9E-67 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THERU_00555 84225c41ddd0aa33a809669b18cbff08 214 TIGRFAM TIGR00017 cmk: cytidylate kinase 1 209 2.0E-55 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THERU_00555 84225c41ddd0aa33a809669b18cbff08 214 Gene3D G3DSA:3.40.50.300 1 214 3.7E-68 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 449 468 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 176 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 312 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 341 357 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 457 1.0E-40 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 SUPERFAMILY SSF51971 151 403 6.47E-65 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 Gene3D G3DSA:3.50.50.60 288 473 1.2E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 Gene3D G3DSA:3.50.50.60 153 281 3.2E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 468 7.1E-211 T 12-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 140 3.2E-38 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 Gene3D G3DSA:1.10.1060.10 4 152 3.7E-37 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 SUPERFAMILY SSF46548 7 162 2.51E-31 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 174 2.8E-20 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 310 2.8E-20 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 410 2.8E-20 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 256 2.8E-20 T 12-10-2018 THERU_07185 83ffd4eae1633f1edb833ff60a75e0ea 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 422 444 2.8E-20 T 12-10-2018 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 282 3.8E-101 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 Gene3D G3DSA:3.40.1010.20 5 277 2.0E-105 T 12-10-2018 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 Pfam PF02401 LytB protein 4 280 7.3E-95 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 2 284 35.941 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 Gene3D G3DSA:3.40.50.11270 13 97 2.0E-105 T 12-10-2018 THERU_00045 62d628fd623c7dd8546a7374869f6595 285 Gene3D G3DSA:3.40.1010.20 98 197 2.0E-105 T 12-10-2018 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 3 66 15.297 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 SUPERFAMILY SSF143034 4 64 1.44E-19 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 Pfam PF01632 Ribosomal protein L35 5 64 4.9E-22 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 PRINTS PR00064 Ribosomal protein L35 signature 38 56 2.6E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 PRINTS PR00064 Ribosomal protein L35 signature 5 22 2.6E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 PRINTS PR00064 Ribosomal protein L35 signature 23 37 2.6E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 5 65 1.8E-24 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 ProSitePatterns PS00936 Ribosomal protein L35 signature. 7 33 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_06295 5e6f8aed8c87777ae83c064ca4d9d838 67 Gene3D G3DSA:2.40.50.530 4 65 3.4E-18 T 12-10-2018 THERU_00355 998d8fe2c01be97afad48fa6e3d420a3 380 Pfam PF00999 Sodium/hydrogen exchanger family 12 363 1.3E-33 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THERU_00355 998d8fe2c01be97afad48fa6e3d420a3 380 Gene3D G3DSA:1.20.1530.20 3 374 2.0E-47 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily THERU_05345 f074dbb20154891ad33f63444c25b9a5 292 Gene3D G3DSA:3.10.520.20 13 285 1.8E-55 T 12-10-2018 THERU_05345 f074dbb20154891ad33f63444c25b9a5 292 SUPERFAMILY SSF143631 19 280 1.33E-57 T 12-10-2018 IPR003374 ApbE-like superfamily THERU_05345 f074dbb20154891ad33f63444c25b9a5 292 Pfam PF02424 ApbE family 23 259 4.4E-42 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 THERU_05345 f074dbb20154891ad33f63444c25b9a5 292 PIRSF PIRSF006268 13 285 3.7E-40 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 Pfam PF01430 Hsp33 protein 22 282 5.2E-59 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 PIRSF PIRSF005261 7 288 2.3E-62 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 Gene3D G3DSA:3.55.30.10 21 236 4.7E-48 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 Gene3D G3DSA:3.90.1280.10 237 288 3.9E-13 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 SUPERFAMILY SSF118352 236 286 2.22E-12 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THERU_01440 6a98c7720e005155422208829b4c8ed0 288 SUPERFAMILY SSF64397 22 243 6.02E-43 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THERU_02060 156682d16d91deeb9d5c958d6b47168b 139 Gene3D G3DSA:3.40.50.720 8 139 4.4E-37 T 12-10-2018 THERU_02060 156682d16d91deeb9d5c958d6b47168b 139 SUPERFAMILY SSF51735 10 137 4.32E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_02060 156682d16d91deeb9d5c958d6b47168b 139 SMART SM00881 16 111 3.5E-22 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_02060 156682d16d91deeb9d5c958d6b47168b 139 Pfam PF13380 CoA binding domain 20 135 1.8E-32 T 12-10-2018 IPR003781 CoA-binding GO:0048037 THERU_03620 b3bc8e0520fa97177ae69c6a5395ae18 99 Pfam PF04304 Protein of unknown function (DUF454) 23 85 3.7E-15 T 12-10-2018 IPR007401 Protein of unknown function DUF454 THERU_02660 c43e3020ca5c95b0f07817e719be40a5 209 SUPERFAMILY SSF53448 4 209 9.18E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_02660 c43e3020ca5c95b0f07817e719be40a5 209 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 208 2.7E-56 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THERU_02660 c43e3020ca5c95b0f07817e719be40a5 209 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 209 1.6E-64 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THERU_02660 c43e3020ca5c95b0f07817e719be40a5 209 Gene3D G3DSA:3.90.550.10 2 209 4.9E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_02660 c43e3020ca5c95b0f07817e719be40a5 209 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 209 39.185 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THERU_00725 f1645c91d0872c5827928c2d9db1251d 134 SUPERFAMILY SSF101116 4 120 8.37E-29 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 THERU_00725 f1645c91d0872c5827928c2d9db1251d 134 TIGRFAM TIGR00208 fliS: flagellar protein FliS 6 119 3.7E-17 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 THERU_00725 f1645c91d0872c5827928c2d9db1251d 134 Gene3D G3DSA:1.20.120.340 2 123 1.3E-34 T 12-10-2018 THERU_00725 f1645c91d0872c5827928c2d9db1251d 134 Pfam PF02561 Flagellar protein FliS 4 119 1.5E-30 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 THERU_00725 f1645c91d0872c5827928c2d9db1251d 134 PIRSF PIRSF039090 2 130 3.6E-25 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 5.3E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 5.3E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 51 66 5.3E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 7 631 4.4E-176 T 12-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 Pfam PF07664 Ferrous iron transport protein B C terminus 412 462 1.8E-13 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 Pfam PF07670 Nucleoside recognition 469 634 9.0E-29 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 Pfam PF07670 Nucleoside recognition 309 397 4.4E-9 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 Gene3D G3DSA:3.40.50.300 2 194 5.4E-47 T 12-10-2018 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 SUPERFAMILY SSF52540 1 170 2.18E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 154 1.8E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THERU_03725 37dbc87c769963e5dbf109ccbf103075 664 Pfam PF02421 Ferrous iron transport protein B 1 156 4.3E-61 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 THERU_00190 3c9b95d8c9b797eb404d9d282b8372e5 319 Pfam PF02754 Cysteine-rich domain 193 263 3.0E-11 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_00190 3c9b95d8c9b797eb404d9d282b8372e5 319 Pfam PF02754 Cysteine-rich domain 8 91 8.0E-19 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_06280 2674398b75a3941d633279d7bb50c133 279 Pfam PF03773 Predicted permease 2 274 7.4E-41 T 12-10-2018 IPR005524 Predicted permease DUF318 THERU_08230 f1c2caaddb73c64aedeb25eb6eee13b7 143 Pfam PF01475 Ferric uptake regulator family 18 133 2.1E-31 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THERU_08230 f1c2caaddb73c64aedeb25eb6eee13b7 143 Gene3D G3DSA:1.10.10.10 4 89 3.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_08230 f1c2caaddb73c64aedeb25eb6eee13b7 143 SUPERFAMILY SSF46785 10 137 3.43E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_08230 f1c2caaddb73c64aedeb25eb6eee13b7 143 Gene3D G3DSA:3.30.1490.190 91 143 9.9E-13 T 12-10-2018 THERU_05970 7432eb16a9966f2f7cea78c7f0c822c2 83 SUPERFAMILY SSF117916 4 76 1.7E-18 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_05970 7432eb16a9966f2f7cea78c7f0c822c2 83 Gene3D G3DSA:3.30.300.130 1 81 4.3E-19 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THERU_05970 7432eb16a9966f2f7cea78c7f0c822c2 83 Pfam PF01106 NifU-like domain 9 74 1.1E-18 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_05970 7432eb16a9966f2f7cea78c7f0c822c2 83 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 16 73 2.0E-5 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 Gene3D G3DSA:3.30.160.110 113 148 2.5E-9 T 12-10-2018 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 Pfam PF14824 Sirohaem biosynthesis protein central 124 145 5.7E-6 T 12-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 Gene3D G3DSA:3.40.50.720 1 112 1.9E-33 T 12-10-2018 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 SUPERFAMILY SSF51735 1 113 7.76E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 Pfam PF13241 Putative NAD(P)-binding 7 115 2.8E-30 T 12-10-2018 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 SUPERFAMILY SSF75615 108 181 4.05E-16 T 12-10-2018 THERU_08130 9e9b14f78a211c313cc7ce9b12515a04 183 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 180 3.5E-44 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THERU_06840 12e3313fef23c0718eb1d17a902c2276 310 Pfam PF01464 Transglycosylase SLT domain 101 194 7.5E-29 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 THERU_06840 12e3313fef23c0718eb1d17a902c2276 310 Gene3D G3DSA:1.10.530.10 85 229 7.6E-33 T 12-10-2018 THERU_06840 12e3313fef23c0718eb1d17a902c2276 310 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 110 138 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THERU_06840 12e3313fef23c0718eb1d17a902c2276 310 SUPERFAMILY SSF53955 67 225 1.97E-38 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily THERU_03475 5f2e13a7638e11c77f0518411718166c 298 Pfam PF02911 Formyl transferase, C-terminal domain 200 293 1.3E-21 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 SUPERFAMILY SSF50486 201 294 2.04E-19 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 SUPERFAMILY SSF53328 1 193 2.22E-60 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 Gene3D G3DSA:3.40.50.12230 1 295 1.8E-95 T 12-10-2018 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 129 152 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 Pfam PF00551 Formyl transferase 1 177 7.1E-41 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 295 33.733 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THERU_03475 5f2e13a7638e11c77f0518411718166c 298 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 295 5.5E-94 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 Gene3D G3DSA:3.30.1360.170 152 299 1.3E-44 T 12-10-2018 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 SUPERFAMILY SSF69796 7 297 6.8E-50 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 155 298 1.4E-32 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 Gene3D G3DSA:3.30.1360.170 2 66 2.0E-11 T 12-10-2018 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 Pfam PF02511 Thymidylate synthase complementing protein 155 298 5.2E-34 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 THERU_02120 a985d959f560fce7ce91d7206f75fcfd 309 Pfam PF02511 Thymidylate synthase complementing protein 7 55 1.3E-5 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 THERU_05780 3fe75aa2367ddee3da07cf558eced4d7 151 Gene3D G3DSA:3.30.700.10 12 150 5.4E-19 T 12-10-2018 THERU_05780 3fe75aa2367ddee3da07cf558eced4d7 151 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05780 3fe75aa2367ddee3da07cf558eced4d7 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 1.6E-10 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05780 3fe75aa2367ddee3da07cf558eced4d7 151 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 31 9.0E-11 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_05780 3fe75aa2367ddee3da07cf558eced4d7 151 SUPERFAMILY SSF54523 12 109 8.63E-17 T 12-10-2018 THERU_07405 694fa1bf9aace62bd3a7bf37d4baf002 473 SUPERFAMILY SSF51445 3 455 4.69E-155 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily THERU_07405 694fa1bf9aace62bd3a7bf37d4baf002 473 Gene3D G3DSA:3.20.20.80 1 472 2.8E-169 T 12-10-2018 THERU_07405 694fa1bf9aace62bd3a7bf37d4baf002 473 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 3 451 1.0E-93 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THERU_07405 694fa1bf9aace62bd3a7bf37d4baf002 473 Pfam PF02446 4-alpha-glucanotransferase 9 450 5.4E-145 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THERU_06390 921324584fb25f1e4d121c134c7979b8 264 SUPERFAMILY SSF52540 4 221 1.22E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06390 921324584fb25f1e4d121c134c7979b8 264 Pfam PF02374 Anion-transporting ATPase 4 216 2.4E-38 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 THERU_06390 921324584fb25f1e4d121c134c7979b8 264 Gene3D G3DSA:3.40.50.300 2 255 1.7E-43 T 12-10-2018 THERU_07785 97391eec35882f5a1eccc357e01a89c8 92 Gene3D G3DSA:3.10.20.30 1 91 2.4E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_07785 97391eec35882f5a1eccc357e01a89c8 92 SUPERFAMILY SSF54285 1 91 6.54E-27 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THERU_07785 97391eec35882f5a1eccc357e01a89c8 92 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 6 91 2.5E-16 T 12-10-2018 IPR010038 MoaD, archaeal-type THERU_07785 97391eec35882f5a1eccc357e01a89c8 92 Pfam PF02597 ThiS family 5 91 8.3E-17 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THERU_07200 730490c1546ab1e368fd6574e79e3e60 369 Pfam PF01098 Cell cycle protein 6 350 1.5E-68 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 SUPERFAMILY SSF53335 79 387 5.19E-73 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 Gene3D G3DSA:3.30.750.80 74 178 4.5E-30 T 12-10-2018 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 Gene3D G3DSA:2.30.130.10 2 70 2.2E-21 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 SMART SM00359 2 87 1.8E-7 T 12-10-2018 IPR002478 PUA domain GO:0003723 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 Gene3D G3DSA:3.40.50.150 179 390 5.1E-67 T 12-10-2018 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 133 360 1.1E-24 T 12-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THERU_07725 cd304ca62cc343ab58b3ec419cecea05 391 SUPERFAMILY SSF88697 3 71 6.08E-15 T 12-10-2018 IPR015947 PUA-like superfamily THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 Gene3D G3DSA:3.40.50.720 209 441 1.1E-56 T 12-10-2018 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 SMART SM00984 326 428 4.9E-28 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 SUPERFAMILY SSF48179 210 299 6.97E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 16 189 3.3E-37 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 PIRSF PIRSF000124 15 441 2.1E-58 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 PIRSF PIRSF500136 6 441 9.2E-148 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 16 411 1.8E-119 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 SUPERFAMILY SSF52413 311 439 3.14E-27 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 326 427 3.9E-20 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 299 2.7E-23 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 SUPERFAMILY SSF51735 16 202 1.35E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_04060 c67a604d8b7f38bbb5b1bab34f113239 441 Gene3D G3DSA:3.40.50.720 2 205 6.7E-65 T 12-10-2018 THERU_03510 5a02ce198846f9e211f6fcb6ed79618d 136 SUPERFAMILY SSF52788 1 131 8.9E-17 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily THERU_03510 5a02ce198846f9e211f6fcb6ed79618d 136 Gene3D G3DSA:3.40.50.2300 1 135 7.4E-20 T 12-10-2018 THERU_03510 5a02ce198846f9e211f6fcb6ed79618d 136 SMART SM00226 1 133 4.5E-8 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THERU_03510 5a02ce198846f9e211f6fcb6ed79618d 136 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 131 1.3E-14 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THERU_03190 e02b7a3c135b06ac373db28eb0277493 233 SUPERFAMILY SSF74653 139 231 1.65E-8 T 12-10-2018 THERU_03190 e02b7a3c135b06ac373db28eb0277493 233 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 177 231 3.2E-9 T 12-10-2018 IPR006260 TonB/TolA, C-terminal THERU_01825 d9368145359924d7756b35be8d07b091 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 226 8.8E-99 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01825 d9368145359924d7756b35be8d07b091 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 226 44.098 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01825 d9368145359924d7756b35be8d07b091 227 SUPERFAMILY SSF52317 1 225 1.03E-73 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_01825 d9368145359924d7756b35be8d07b091 227 PIRSF PIRSF001586 1 227 1.5E-84 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 THERU_01825 d9368145359924d7756b35be8d07b091 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 5 210 2.1E-47 T 12-10-2018 THERU_01825 d9368145359924d7756b35be8d07b091 227 Gene3D G3DSA:3.40.50.880 1 226 4.4E-69 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_01825 d9368145359924d7756b35be8d07b091 227 SMART SM01211 1 227 4.5E-127 T 12-10-2018 THERU_03890 788180547029aa3f9211aae1cf4e9c17 115 Pfam PF01934 Protein of unknown function DUF86 13 109 3.7E-30 T 12-10-2018 IPR008201 Protein of unknown function DUF86 THERU_03015 c41951366e2613d15f695f5744e667f4 115 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 15 113 6.6E-32 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_03015 c41951366e2613d15f695f5744e667f4 115 Gene3D G3DSA:1.20.58.1610 1 114 8.8E-36 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_03015 c41951366e2613d15f695f5744e667f4 115 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 114 16.422 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 THERU_02900 ebf670121a5ea1a19b91954c84a5a791 398 Pfam PF13524 Glycosyl transferases group 1 303 383 9.3E-14 T 12-10-2018 THERU_02900 ebf670121a5ea1a19b91954c84a5a791 398 SUPERFAMILY SSF53756 225 388 2.01E-5 T 12-10-2018 THERU_02900 ebf670121a5ea1a19b91954c84a5a791 398 Gene3D G3DSA:3.40.50.2000 219 379 1.1E-5 T 12-10-2018 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 60 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 Gene3D G3DSA:2.20.150.40 1 49 3.6E-22 T 12-10-2018 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 50 2.8E-18 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-10 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.6E-10 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 SUPERFAMILY SSF143800 1 49 7.46E-18 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07600 07d2742da0ddd1874aaf4f5c1022e754 65 Pfam PF01197 Ribosomal protein L31 1 50 9.9E-20 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_04715 cb14785001228b6add71dbbf5c61e05f 108 Gene3D G3DSA:2.60.40.10 2 108 6.8E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold THERU_04715 cb14785001228b6add71dbbf5c61e05f 108 Pfam PF08770 Sulphur oxidation protein SoxZ 13 103 4.8E-23 T 12-10-2018 IPR014880 Sulphur oxidation protein SoxZ THERU_04715 cb14785001228b6add71dbbf5c61e05f 108 SUPERFAMILY SSF81296 4 107 9.94E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set THERU_04715 cb14785001228b6add71dbbf5c61e05f 108 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 12 105 4.6E-25 T 12-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ THERU_05520 12187137306a1c3a4a5fead897e06360 164 Gene3D G3DSA:2.40.50.100 18 151 1.5E-31 T 12-10-2018 THERU_05520 12187137306a1c3a4a5fead897e06360 164 Pfam PF13533 Biotin-lipoyl like 20 66 8.7E-11 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain THERU_05520 12187137306a1c3a4a5fead897e06360 164 Gene3D G3DSA:1.10.287.470 53 126 1.5E-31 T 12-10-2018 THERU_05520 12187137306a1c3a4a5fead897e06360 164 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 18 150 7.5E-29 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THERU_05520 12187137306a1c3a4a5fead897e06360 164 SUPERFAMILY SSF111369 18 162 1.57E-21 T 12-10-2018 THERU_00650 6ae17c6c9269caeb67cfeff5d2c4d8fa 461 SUPERFAMILY SSF111283 6 459 2.75E-121 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 THERU_00650 6ae17c6c9269caeb67cfeff5d2c4d8fa 461 PIRSF PIRSF004919 5 460 5.5E-139 T 12-10-2018 IPR025502 TldD THERU_00650 6ae17c6c9269caeb67cfeff5d2c4d8fa 461 Gene3D G3DSA:3.30.2290.10 2 220 1.9E-18 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal THERU_00650 6ae17c6c9269caeb67cfeff5d2c4d8fa 461 Pfam PF01523 Putative modulator of DNA gyrase 25 313 1.3E-63 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 5 444 3.6E-171 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 SUPERFAMILY SSF53383 63 445 6.14E-42 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 Gene3D G3DSA:3.90.1150.110 7 436 4.2E-167 T 12-10-2018 THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 Gene3D G3DSA:3.40.640.10 85 344 4.2E-167 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 448 183.458 T 12-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THERU_02590 62b7e84c03f1aeaf8c7360bcc7e47573 448 Pfam PF03841 L-seryl-tRNA selenium transferase 73 431 9.2E-152 T 12-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THERU_01165 e75a7285bea3bb55258889a07d8b8241 285 Gene3D G3DSA:3.30.450.90 5 99 3.7E-7 T 12-10-2018 THERU_01165 e75a7285bea3bb55258889a07d8b8241 285 Gene3D G3DSA:3.40.50.300 101 275 4.0E-15 T 12-10-2018 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 Hamap MF_00258 Glutamate racemase [murI]. 1 242 36.409 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 Pfam PF01177 Asp/Glu/Hydantoin racemase 3 207 6.7E-45 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 TIGRFAM TIGR00067 glut_race: glutamate racemase 3 217 7.1E-70 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 Gene3D G3DSA:3.40.50.1860 3 232 1.6E-92 T 12-10-2018 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 SUPERFAMILY SSF53681 1 104 1.54E-37 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 174 184 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 Gene3D G3DSA:3.40.50.1860 92 200 1.6E-92 T 12-10-2018 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06405 3830b7ff81f48c02cd3a81eda3dd1d31 254 SUPERFAMILY SSF53681 106 245 7.52E-41 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THERU_06825 a206b330c8c6260fdb17dcd597bf443b 313 Gene3D G3DSA:3.40.50.720 3 312 1.9E-56 T 12-10-2018 THERU_06825 a206b330c8c6260fdb17dcd597bf443b 313 Pfam PF13460 NAD(P)H-binding 8 153 2.4E-25 T 12-10-2018 IPR016040 NAD(P)-binding domain THERU_06825 a206b330c8c6260fdb17dcd597bf443b 313 SUPERFAMILY SSF51735 1 274 3.34E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_03340 bfecdf29fc61ad9f5402ae1703b79922 67 Gene3D G3DSA:2.30.30.100 1 66 2.3E-25 T 12-10-2018 THERU_03340 bfecdf29fc61ad9f5402ae1703b79922 67 Pfam PF17209 Hfq protein 7 64 4.6E-21 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_03340 bfecdf29fc61ad9f5402ae1703b79922 67 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 5.1E-23 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_03340 bfecdf29fc61ad9f5402ae1703b79922 67 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 65 23.354 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THERU_03340 bfecdf29fc61ad9f5402ae1703b79922 67 SUPERFAMILY SSF50182 6 64 2.32E-18 T 12-10-2018 IPR010920 LSM domain superfamily THERU_05430 337f7ece4aaa706e6d076ba16f337c3c 143 Pfam PF02915 Rubrerythrin 12 137 3.0E-33 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 THERU_05430 337f7ece4aaa706e6d076ba16f337c3c 143 SUPERFAMILY SSF47240 6 142 9.55E-44 T 12-10-2018 IPR009078 Ferritin-like superfamily THERU_05430 337f7ece4aaa706e6d076ba16f337c3c 143 Gene3D G3DSA:1.20.1260.10 1 142 2.5E-52 T 12-10-2018 IPR012347 Ferritin-like THERU_00035 fea59d4fe987c8c07adfd857f11490f2 106 SUPERFAMILY SSF54913 4 104 5.93E-34 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THERU_00035 fea59d4fe987c8c07adfd857f11490f2 106 Pfam PF03091 CutA1 divalent ion tolerance protein 6 102 7.3E-35 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 THERU_00035 fea59d4fe987c8c07adfd857f11490f2 106 Gene3D G3DSA:3.30.70.120 1 105 3.9E-37 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THERU_02750 0ab65917b99253a503519fd1df4c9820 374 Gene3D G3DSA:3.90.1150.10 14 370 5.0E-151 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 210 247 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 PIRSF PIRSF000521 2 157 9.8E-15 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 PIRSF PIRSF000521 156 374 5.2E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 3 374 7.0E-157 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 374 68.302 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 Gene3D G3DSA:3.40.640.10 47 291 5.0E-151 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02750 0ab65917b99253a503519fd1df4c9820 374 SUPERFAMILY SSF53383 4 374 7.37E-122 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02750 0ab65917b99253a503519fd1df4c9820 374 Pfam PF00202 Aminotransferase class-III 10 374 8.7E-116 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THERU_07590 645d3ebf5a51ffa05f89af2cbf0614f6 386 SUPERFAMILY SSF56796 3 385 1.44E-112 T 12-10-2018 THERU_07590 645d3ebf5a51ffa05f89af2cbf0614f6 386 Gene3D G3DSA:3.40.50.1970 1 187 2.7E-55 T 12-10-2018 THERU_07590 645d3ebf5a51ffa05f89af2cbf0614f6 386 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 375 5.7E-112 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 THERU_07590 645d3ebf5a51ffa05f89af2cbf0614f6 386 Gene3D G3DSA:1.20.1090.10 190 386 2.3E-54 T 12-10-2018 THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 209 246 1.8E-14 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 SUPERFAMILY SSF52343 91 247 2.49E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 SUPERFAMILY SSF63380 3 94 2.15E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 Gene3D G3DSA:2.40.30.10 2 94 5.3E-24 T 12-10-2018 THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 Gene3D G3DSA:2.10.240.10 209 248 1.1E-13 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 PIRSF PIRSF006816 1 248 6.0E-65 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 THERU_06810 9025c4cdacafc8f205a907a02fe1c12c 248 Gene3D G3DSA:3.40.50.80 99 208 5.9E-21 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 SUPERFAMILY SSF51735 106 267 1.89E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 267 33.754 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 189 1.3E-9 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 SUPERFAMILY SSF53223 2 105 3.63E-33 T 12-10-2018 THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 9 268 4.4E-78 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 6.1E-32 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 Gene3D G3DSA:3.40.50.10860 9 254 1.3E-93 T 12-10-2018 THERU_05975 cb07f9942ffcf35036e693b7c8186d49 272 Gene3D G3DSA:3.40.50.720 105 234 1.3E-93 T 12-10-2018 THERU_04525 d5d787e3db50857a8c3e779351b3f482 245 Pfam PF02405 Permease MlaE 32 243 1.6E-79 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 THERU_04525 d5d787e3db50857a8c3e779351b3f482 245 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 3 245 1.4E-99 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria THERU_02055 76defc8cece3ec85c4df497ff30357f6 213 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 4 198 6.0E-73 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_02055 76defc8cece3ec85c4df497ff30357f6 213 Pfam PF02581 Thiamine monophosphate synthase 5 185 1.1E-64 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_02055 76defc8cece3ec85c4df497ff30357f6 213 Gene3D G3DSA:3.20.20.70 1 208 6.4E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02055 76defc8cece3ec85c4df497ff30357f6 213 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 203 27.537 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_02055 76defc8cece3ec85c4df497ff30357f6 213 SUPERFAMILY SSF51391 3 204 8.11E-65 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THERU_04830 538625cbdb3313f85059dc734bb33c1b 349 Pfam PF13557 Putative MetA-pathway of phenol degradation 95 262 4.4E-5 T 12-10-2018 IPR025737 MetA-pathway of phenol degradation, putative THERU_06360 a57d202730e34b656ab4f5fa6935ec7e 211 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 196 2.7E-66 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THERU_06360 a57d202730e34b656ab4f5fa6935ec7e 211 PIRSF PIRSF000709 2 172 1.1E-24 T 12-10-2018 THERU_06360 a57d202730e34b656ab4f5fa6935ec7e 211 Gene3D G3DSA:3.40.50.1240 1 211 2.6E-82 T 12-10-2018 IPR029033 Histidine phosphatase superfamily THERU_06360 a57d202730e34b656ab4f5fa6935ec7e 211 SUPERFAMILY SSF53254 3 205 2.62E-65 T 12-10-2018 IPR029033 Histidine phosphatase superfamily THERU_06360 a57d202730e34b656ab4f5fa6935ec7e 211 SMART SM00855 3 157 1.1E-20 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THERU_00615 e90e2cc9a26ecff1f372ecbfefadfeaf 221 ProSitePatterns PS00194 Thioredoxin family active site. 118 136 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THERU_00615 e90e2cc9a26ecff1f372ecbfefadfeaf 221 Pfam PF00578 AhpC/TSA family 94 202 3.4E-23 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THERU_00615 e90e2cc9a26ecff1f372ecbfefadfeaf 221 Gene3D G3DSA:3.40.30.10 63 221 2.0E-43 T 12-10-2018 THERU_00615 e90e2cc9a26ecff1f372ecbfefadfeaf 221 SUPERFAMILY SSF52833 44 220 1.04E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 Gene3D G3DSA:1.10.3430.10 13 424 1.4E-147 T 12-10-2018 IPR029020 Ammonium/urea transporter THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 PRINTS PR00342 Rhesus blood group protein signature 248 270 1.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 PRINTS PR00342 Rhesus blood group protein signature 303 321 1.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 PRINTS PR00342 Rhesus blood group protein signature 125 141 1.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 PRINTS PR00342 Rhesus blood group protein signature 217 235 1.2E-6 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 ProSitePatterns PS01219 Ammonium transporters signature. 181 206 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 TIGRFAM TIGR00836 amt: ammonium transporter 29 422 8.7E-147 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 SUPERFAMILY SSF111352 25 403 5.62E-131 T 12-10-2018 THERU_07060 43c8ee4ef599b76966f00e977dc9d5c8 424 Pfam PF00909 Ammonium Transporter Family 31 422 7.0E-132 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THERU_06195 434733fa1ade343cf0d107a05ea8e248 341 SUPERFAMILY SSF55073 190 338 7.3E-45 T 12-10-2018 IPR029787 Nucleotide cyclase THERU_06195 434733fa1ade343cf0d107a05ea8e248 341 Gene3D G3DSA:3.30.70.270 179 340 3.7E-52 T 12-10-2018 THERU_06195 434733fa1ade343cf0d107a05ea8e248 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 182 339 9.4E-49 T 12-10-2018 IPR000160 GGDEF domain THERU_06195 434733fa1ade343cf0d107a05ea8e248 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 185 339 7.6E-45 T 12-10-2018 IPR000160 GGDEF domain THERU_06195 434733fa1ade343cf0d107a05ea8e248 341 SMART SM00267 174 340 3.0E-50 T 12-10-2018 IPR000160 GGDEF domain THERU_04900 aa22f4ca08fefa812d99906d177f38f8 238 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 21 229 1.8E-89 T 12-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 THERU_04900 aa22f4ca08fefa812d99906d177f38f8 238 PIRSF PIRSF005624 12 237 3.0E-95 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 THERU_04900 aa22f4ca08fefa812d99906d177f38f8 238 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 47 208 8.8E-31 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THERU_04900 aa22f4ca08fefa812d99906d177f38f8 238 SUPERFAMILY SSF52540 9 226 9.59E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_04900 aa22f4ca08fefa812d99906d177f38f8 238 Gene3D G3DSA:3.40.50.300 27 236 5.4E-65 T 12-10-2018 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 Gene3D G3DSA:3.30.460.30 1 154 5.9E-50 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 Gene3D G3DSA:3.40.50.720 157 308 6.7E-43 T 12-10-2018 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 PIRSF PIRSF000445 1 398 5.6E-128 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 SUPERFAMILY SSF69742 1 154 2.09E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 167 301 9.3E-44 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 SUPERFAMILY SSF51735 158 309 3.73E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 386 25.352 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 1 354 1.2E-125 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_08005 914f6eff364c2d7691d51a00ecdf129c 408 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 5 152 1.2E-43 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THERU_02850 b5022bdd4095a8fed8d6610fb9ab8bb4 137 Pfam PF02391 MoaE protein 15 117 4.8E-31 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THERU_02850 b5022bdd4095a8fed8d6610fb9ab8bb4 137 SUPERFAMILY SSF54690 7 134 3.01E-41 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THERU_02850 b5022bdd4095a8fed8d6610fb9ab8bb4 137 Gene3D G3DSA:3.90.1170.40 1 127 8.4E-47 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THERU_02500 94a96edb380757ed65aafa351cd8bbb3 124 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 18 116 1.2E-31 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02500 94a96edb380757ed65aafa351cd8bbb3 124 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 117 16.877 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 THERU_02500 94a96edb380757ed65aafa351cd8bbb3 124 Gene3D G3DSA:1.20.58.1610 1 117 4.0E-36 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02475 25c02f107ffedda2dc328d35a0573d79 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 97 1.0E-20 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THERU_02475 25c02f107ffedda2dc328d35a0573d79 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 102 19.406 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THERU_03465 eb1b3225c815744da2f5f23af45c3c9a 126 SUPERFAMILY SSF103247 1 124 1.11E-33 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_03465 eb1b3225c815744da2f5f23af45c3c9a 126 PIRSF PIRSF021774 1 126 2.2E-34 T 12-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 THERU_03465 eb1b3225c815744da2f5f23af45c3c9a 126 Pfam PF03625 Domain of unknown function DUF302 35 95 2.1E-15 T 12-10-2018 IPR005180 Domain of unknown function DUF302 THERU_03465 eb1b3225c815744da2f5f23af45c3c9a 126 Gene3D G3DSA:3.30.310.70 2 125 5.7E-38 T 12-10-2018 IPR035923 TT1751-like domain superfamily THERU_04075 08b34faf4a26263b6a7c621223740196 376 Pfam PF13477 Glycosyl transferase 4-like 9 153 2.1E-17 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_04075 08b34faf4a26263b6a7c621223740196 376 Pfam PF00534 Glycosyl transferases group 1 189 350 5.2E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_04075 08b34faf4a26263b6a7c621223740196 376 Gene3D G3DSA:3.40.50.2000 176 356 8.3E-60 T 12-10-2018 THERU_04075 08b34faf4a26263b6a7c621223740196 376 Gene3D G3DSA:3.40.50.2000 26 366 8.3E-60 T 12-10-2018 THERU_04075 08b34faf4a26263b6a7c621223740196 376 SUPERFAMILY SSF53756 24 374 5.76E-74 T 12-10-2018 THERU_05080 05e70ad1aa25971d42a9a0ebbf2be071 246 SUPERFAMILY SSF56317 2 243 1.31E-59 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_05080 05e70ad1aa25971d42a9a0ebbf2be071 246 Gene3D G3DSA:3.60.110.10 1 246 1.5E-64 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_05080 05e70ad1aa25971d42a9a0ebbf2be071 246 Pfam PF00795 Carbon-nitrogen hydrolase 3 239 5.9E-38 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THERU_05050 8471091695ef7f1d47cab847f3b4db36 297 TIGRFAM TIGR02590 cas_Csh2: CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI 7 279 3.7E-79 T 12-10-2018 IPR013419 CRISPR-associated protein Csh2 THERU_05050 8471091695ef7f1d47cab847f3b4db36 297 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 5 279 7.6E-61 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C THERU_05050 8471091695ef7f1d47cab847f3b4db36 297 Pfam PF05107 CRISPR-associated protein Cas7 6 252 1.6E-53 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 Gene3D G3DSA:3.40.190.10 94 270 7.8E-120 T 12-10-2018 THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 Gene3D G3DSA:3.40.190.10 21 315 7.8E-120 T 12-10-2018 THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 Pfam PF12849 PBP superfamily domain 18 297 1.2E-64 T 12-10-2018 IPR024370 PBP domain THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 SUPERFAMILY SSF53850 19 328 4.6E-103 T 12-10-2018 THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 20 325 1.4E-116 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THERU_03160 12f2ef386674d98bc81a1ba979edac74 331 PIRSF PIRSF002756 5 329 8.1E-111 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THERU_08350 01d098a1bac3ffdd8c618da651480dea 263 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site THERU_08350 01d098a1bac3ffdd8c618da651480dea 263 SUPERFAMILY SSF48576 6 236 4.08E-62 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily THERU_08350 01d098a1bac3ffdd8c618da651480dea 263 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 95 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site THERU_08350 01d098a1bac3ffdd8c618da651480dea 263 Gene3D G3DSA:1.10.600.10 7 258 4.1E-69 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily THERU_08350 01d098a1bac3ffdd8c618da651480dea 263 Pfam PF00348 Polyprenyl synthetase 29 237 1.4E-41 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 THERU_00195 0a61734518928547d8bb6075ffd36853 151 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 13 141 30.898 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THERU_00195 0a61734518928547d8bb6075ffd36853 151 SUPERFAMILY SSF51230 17 136 1.7E-28 T 12-10-2018 IPR011053 Single hybrid motif THERU_00195 0a61734518928547d8bb6075ffd36853 151 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 58 87 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THERU_00195 0a61734518928547d8bb6075ffd36853 151 Pfam PF01597 Glycine cleavage H-protein 16 136 8.8E-40 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THERU_00195 0a61734518928547d8bb6075ffd36853 151 Gene3D G3DSA:2.40.50.100 11 138 6.5E-32 T 12-10-2018 THERU_05525 94bdb77d977bfdb0768fd1502c8abf23 426 SUPERFAMILY SSF56954 3 411 9.81E-40 T 12-10-2018 THERU_05525 94bdb77d977bfdb0768fd1502c8abf23 426 Pfam PF02321 Outer membrane efflux protein 23 202 2.1E-19 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_05525 94bdb77d977bfdb0768fd1502c8abf23 426 Pfam PF02321 Outer membrane efflux protein 227 409 8.2E-6 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_05525 94bdb77d977bfdb0768fd1502c8abf23 426 Gene3D G3DSA:1.20.1600.10 10 410 6.1E-34 T 12-10-2018 THERU_08300 3479bb47cdacb22239074698333a0822 579 SUPERFAMILY SSF53850 45 578 1.14E-122 T 12-10-2018 THERU_08300 3479bb47cdacb22239074698333a0822 579 Gene3D G3DSA:3.10.105.10 310 549 1.5E-127 T 12-10-2018 THERU_08300 3479bb47cdacb22239074698333a0822 579 Gene3D G3DSA:3.40.190.10 57 563 1.5E-127 T 12-10-2018 THERU_08300 3479bb47cdacb22239074698333a0822 579 Gene3D G3DSA:3.90.76.10 79 206 1.5E-127 T 12-10-2018 THERU_08300 3479bb47cdacb22239074698333a0822 579 PIRSF PIRSF002741 6 578 1.6E-94 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THERU_08300 3479bb47cdacb22239074698333a0822 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 483 4.3E-81 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 13 493 4.9E-135 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 1.7E-32 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 171 195 1.7E-32 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 1.7E-32 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 334 353 1.7E-32 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 141 160 1.7E-32 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02510 84fa3f6150607ef9b01c3d89a7bee0bb 506 Pfam PF00361 Proton-conducting membrane transporter 136 428 1.6E-65 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06305 68424b0144f2a9c8051578aaa1e7b261 238 Gene3D G3DSA:2.102.10.10 31 218 4.4E-35 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_06305 68424b0144f2a9c8051578aaa1e7b261 238 SUPERFAMILY SSF50022 48 186 8.51E-17 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THERU_06305 68424b0144f2a9c8051578aaa1e7b261 238 Pfam PF00355 Rieske [2Fe-2S] domain 103 174 2.1E-6 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 Pfam PF01264 Chorismate synthase 4 362 8.1E-122 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 Hamap MF_00300 Chorismate synthase [aroC]. 3 369 36.065 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 Gene3D G3DSA:3.60.150.10 3 387 1.6E-152 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 TIGRFAM TIGR00033 aroC: chorismate synthase 4 366 1.6E-126 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 PIRSF PIRSF001456 1 382 1.6E-127 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 SUPERFAMILY SSF103263 3 386 7.98E-143 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_04530 046f9b151ad177ddf2bcca337ec02f38 387 ProSitePatterns PS00787 Chorismate synthase signature 1. 9 24 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THERU_02460 8f7bf178e5becedc8ad9cb345068ae4d 460 Pfam PF00361 Proton-conducting membrane transporter 118 404 1.1E-55 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02460 8f7bf178e5becedc8ad9cb345068ae4d 460 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 3 455 6.3E-114 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THERU_02460 8f7bf178e5becedc8ad9cb345068ae4d 460 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 1 455 15.925 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THERU_04395 b03599fd32ee3db00bce32334fc65ff7 316 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 6 310 1.5E-50 T 12-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 THERU_04395 b03599fd32ee3db00bce32334fc65ff7 316 Pfam PF03787 RAMP superfamily 8 310 3.9E-33 T 12-10-2018 IPR005537 CRISPR type III-associated RAMP protein THERU_03185 2613c5aceeb8184dafda205e342995be 264 SUPERFAMILY SSF51569 2 249 1.35E-78 T 12-10-2018 THERU_03185 2613c5aceeb8184dafda205e342995be 264 Gene3D G3DSA:3.20.20.70 1 261 1.2E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_03185 2613c5aceeb8184dafda205e342995be 264 SMART SM01133 18 233 5.5E-62 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03185 2613c5aceeb8184dafda205e342995be 264 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 1 261 60.631 T 12-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 THERU_03185 2613c5aceeb8184dafda205e342995be 264 Pfam PF01791 DeoC/LacD family aldolase 19 232 2.1E-61 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03185 2613c5aceeb8184dafda205e342995be 264 PIRSF PIRSF038992 1 262 2.3E-95 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 THERU_03185 2613c5aceeb8184dafda205e342995be 264 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 1 257 4.7E-115 T 12-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 THERU_00425 52e3dd271b8623c5f21e8724439cb279 365 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 80 3.4E-8 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 THERU_00425 52e3dd271b8623c5f21e8724439cb279 365 SUPERFAMILY SSF48452 123 258 1.06E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00425 52e3dd271b8623c5f21e8724439cb279 365 Gene3D G3DSA:1.25.40.10 123 312 1.0E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05925 fd5c4480002bc1553082d794570a016d 499 Pfam PF11997 Domain of unknown function (DUF3492) 11 282 6.7E-76 T 12-10-2018 IPR022622 Domain of unknown function DUF3492 THERU_05925 fd5c4480002bc1553082d794570a016d 499 Gene3D G3DSA:3.40.50.2000 302 481 6.8E-35 T 12-10-2018 THERU_05925 fd5c4480002bc1553082d794570a016d 499 SUPERFAMILY SSF53756 12 495 1.41E-61 T 12-10-2018 THERU_05925 fd5c4480002bc1553082d794570a016d 499 Pfam PF00534 Glycosyl transferases group 1 307 472 7.1E-26 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 SUPERFAMILY SSF52540 1 301 2.65E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 SUPERFAMILY SSF49764 319 394 3.49E-8 T 12-10-2018 IPR008978 HSP20-like chaperone THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 Pfam PF02374 Anion-transporting ATPase 1 309 2.7E-106 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 Gene3D G3DSA:3.40.50.300 1 323 4.3E-81 T 12-10-2018 THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 307 6.9E-78 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 THERU_00545 3477aa2c47dbaf42724881a280ef63f9 394 Gene3D G3DSA:2.60.40.790 324 394 1.9E-14 T 12-10-2018 IPR008978 HSP20-like chaperone THERU_05220 ab9a21de941cfb16304cf04458e12906 124 Gene3D G3DSA:3.40.30.10 23 124 1.2E-17 T 12-10-2018 THERU_05220 ab9a21de941cfb16304cf04458e12906 124 SUPERFAMILY SSF52833 45 121 1.09E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_05220 ab9a21de941cfb16304cf04458e12906 124 Pfam PF00085 Thioredoxin 42 120 1.6E-13 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 THERU_03285 c9116fe0114821d458e31bfdeb560fd3 284 Pfam PF02628 Cytochrome oxidase assembly protein 50 267 8.2E-15 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 THERU_03285 c9116fe0114821d458e31bfdeb560fd3 284 Pfam PF02628 Cytochrome oxidase assembly protein 3 46 2.5E-9 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 THERU_03635 4c4bb1256812efa8bea3a29b6b49d61a 250 Pfam PF01925 Sulfite exporter TauE/SafE 8 239 8.5E-37 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THERU_01200 907e4397c11333cf9fbe0ae8a674f56a 356 Pfam PF02481 DNA recombination-mediator protein A 71 271 1.6E-61 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THERU_01200 907e4397c11333cf9fbe0ae8a674f56a 356 SUPERFAMILY SSF102405 80 267 3.36E-26 T 12-10-2018 THERU_01200 907e4397c11333cf9fbe0ae8a674f56a 356 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 69 271 1.8E-63 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THERU_01200 907e4397c11333cf9fbe0ae8a674f56a 356 Gene3D G3DSA:3.40.50.450 1 280 4.3E-73 T 12-10-2018 THERU_01220 cf1754aae8b72533c0a255b8da019126 1023 Pfam PF04851 Type III restriction enzyme, res subunit 126 280 3.8E-15 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THERU_01220 cf1754aae8b72533c0a255b8da019126 1023 SUPERFAMILY SSF52540 141 554 5.67E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01220 cf1754aae8b72533c0a255b8da019126 1023 SMART SM00487 119 306 0.0018 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THERU_01220 cf1754aae8b72533c0a255b8da019126 1023 Gene3D G3DSA:3.40.50.300 121 307 6.8E-13 T 12-10-2018 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 Gene3D G3DSA:3.40.50.1370 127 272 5.0E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 211 220 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 250 255 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 288 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 1.9E-21 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 SUPERFAMILY SSF53671 2 294 6.39E-72 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 246 255 1.4E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 281 1.4E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 1.4E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 1.4E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 Gene3D G3DSA:3.40.50.1370 7 288 5.0E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 139 5.9E-32 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 290 1.0E-15 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THERU_07530 c020b31bce364456fa169e4b69b1bef6 296 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THERU_04690 429fcf04ebb75ab3bcb1aa5349c58cb6 323 Pfam PF00753 Metallo-beta-lactamase superfamily 49 237 1.3E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_04690 429fcf04ebb75ab3bcb1aa5349c58cb6 323 Gene3D G3DSA:3.60.15.10 17 263 2.9E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_04690 429fcf04ebb75ab3bcb1aa5349c58cb6 323 SMART SM00849 51 237 5.7E-26 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_04690 429fcf04ebb75ab3bcb1aa5349c58cb6 323 SUPERFAMILY SSF56281 5 283 1.54E-63 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_00585 9608e0e420b413d2c98373f3fb61d946 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 306 5.7E-59 T 12-10-2018 IPR016040 NAD(P)-binding domain THERU_00585 9608e0e420b413d2c98373f3fb61d946 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 322 6.0E-134 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 THERU_00585 9608e0e420b413d2c98373f3fb61d946 328 Gene3D G3DSA:3.40.50.720 3 251 1.2E-122 T 12-10-2018 THERU_00585 9608e0e420b413d2c98373f3fb61d946 328 SUPERFAMILY SSF51735 1 322 5.22E-96 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_00585 9608e0e420b413d2c98373f3fb61d946 328 Gene3D G3DSA:3.90.25.10 172 305 1.2E-122 T 12-10-2018 THERU_08455 ce7ee40056c1453ddabb9af34bf57a81 223 Gene3D G3DSA:3.40.50.300 1 219 7.7E-58 T 12-10-2018 THERU_08455 ce7ee40056c1453ddabb9af34bf57a81 223 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THERU_08455 ce7ee40056c1453ddabb9af34bf57a81 223 SUPERFAMILY SSF52540 4 200 2.57E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_08455 ce7ee40056c1453ddabb9af34bf57a81 223 SMART SM00382 30 212 2.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_08455 ce7ee40056c1453ddabb9af34bf57a81 223 Pfam PF00005 ABC transporter 22 155 3.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_01700 382e3792b00135fdfac3ffc8acd522fd 202 SUPERFAMILY SSF51261 56 201 1.26E-57 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_01700 382e3792b00135fdfac3ffc8acd522fd 202 Pfam PF01551 Peptidase family M23 103 197 2.0E-34 T 12-10-2018 IPR016047 Peptidase M23 THERU_01700 382e3792b00135fdfac3ffc8acd522fd 202 Gene3D G3DSA:2.70.70.10 49 202 3.2E-49 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 44 245 7.0E-78 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 100 112 6.8E-17 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 112 126 6.8E-17 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 40 49 6.8E-17 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 167 179 6.8E-17 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 235 245 6.8E-17 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 61 81 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 61 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 174 194 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 216 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 219 244 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 81 100 3.6E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 174 189 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 222 234 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_08270 1bb0303ba9b8995f022cd620af46fa50 246 Pfam PF00813 FliP family 44 241 2.5E-74 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THERU_06680 bd480ebb44bd12e8e03092d5d8fccd1c 60 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 3 57 1.7E-11 T 12-10-2018 THERU_06680 bd480ebb44bd12e8e03092d5d8fccd1c 60 SUPERFAMILY SSF54862 1 58 4.65E-9 T 12-10-2018 THERU_06680 bd480ebb44bd12e8e03092d5d8fccd1c 60 Gene3D G3DSA:3.30.70.20 1 60 6.9E-13 T 12-10-2018 THERU_07675 2e091ed2b003c30727be62446bbe2805 95 Pfam PF09876 Predicted metal-binding protein (DUF2103) 6 83 1.9E-12 T 12-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding THERU_05965 55de5c54550ead6f95f6c07388dd1138 85 Pfam PF08984 Domain of unknown function (DUF1858) 5 60 2.1E-12 T 12-10-2018 IPR015077 Domain of unknown function DUF1858 THERU_05965 55de5c54550ead6f95f6c07388dd1138 85 SUPERFAMILY SSF140683 2 73 1.44E-12 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily THERU_05965 55de5c54550ead6f95f6c07388dd1138 85 Gene3D G3DSA:1.10.3910.10 1 82 4.7E-8 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily THERU_04105 9153367917d136c83dd9f7e09a8bffaf 354 Pfam PF00563 EAL domain 114 340 4.8E-57 T 12-10-2018 IPR001633 EAL domain THERU_04105 9153367917d136c83dd9f7e09a8bffaf 354 SMART SM00052 102 345 9.0E-39 T 12-10-2018 IPR001633 EAL domain THERU_04105 9153367917d136c83dd9f7e09a8bffaf 354 SUPERFAMILY SSF141868 108 343 4.18E-67 T 12-10-2018 IPR035919 EAL domain superfamily THERU_04105 9153367917d136c83dd9f7e09a8bffaf 354 Gene3D G3DSA:3.20.20.450 102 346 6.7E-64 T 12-10-2018 IPR035919 EAL domain superfamily THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 245 1.1E-53 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 Pfam PF01311 Bacterial export proteins, family 1 10 241 2.3E-51 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 176 198 2.3E-24 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 77 96 2.3E-24 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 198 217 2.3E-24 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THERU_08260 11d3eb697f0a76d7c978d51968e8b5e6 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 18 39 2.3E-24 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 3 280 1.2E-100 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 Pfam PF02569 Pantoate-beta-alanine ligase 4 280 3.4E-102 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 SUPERFAMILY SSF52374 3 283 4.44E-101 T 12-10-2018 THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 Gene3D G3DSA:3.30.1300.10 180 287 9.1E-30 T 12-10-2018 THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 Gene3D G3DSA:3.40.50.620 2 179 1.2E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_01785 2508bc76251c30f3ebc9e7ff40201479 287 Hamap MF_00158 Pantothenate synthetase [panC]. 3 282 40.07 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THERU_02685 cd35c466fc258499568ac3eb888f1abc 180 Gene3D G3DSA:2.70.70.10 36 176 8.4E-19 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_02685 cd35c466fc258499568ac3eb888f1abc 180 Pfam PF01551 Peptidase family M23 81 174 4.1E-18 T 12-10-2018 IPR016047 Peptidase M23 THERU_02685 cd35c466fc258499568ac3eb888f1abc 180 SUPERFAMILY SSF51261 71 158 1.31E-21 T 12-10-2018 IPR011055 Duplicated hybrid motif THERU_07720 ba48639c81292fb952eea946aa8e093f 184 Pfam PF01965 DJ-1/PfpI family 3 164 7.6E-49 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 THERU_07720 ba48639c81292fb952eea946aa8e093f 184 Gene3D G3DSA:3.40.50.880 1 184 1.4E-59 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_07720 ba48639c81292fb952eea946aa8e093f 184 SUPERFAMILY SSF52317 3 181 1.35E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_07720 ba48639c81292fb952eea946aa8e093f 184 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 177 1.1E-56 T 12-10-2018 IPR006287 Protein/nucleic acid deglycase DJ-1 Reactome: R-HSA-3899300 THERU_05365 0665aac5a01cc3c19baf3154a963c045 107 SMART SM00450 7 103 3.8E-27 T 12-10-2018 IPR001763 Rhodanese-like domain THERU_05365 0665aac5a01cc3c19baf3154a963c045 107 Gene3D G3DSA:3.40.250.10 8 106 1.6E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily THERU_05365 0665aac5a01cc3c19baf3154a963c045 107 Pfam PF00581 Rhodanese-like domain 8 97 4.3E-17 T 12-10-2018 IPR001763 Rhodanese-like domain THERU_05365 0665aac5a01cc3c19baf3154a963c045 107 SUPERFAMILY SSF52821 3 97 2.1E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily THERU_04015 1cafbd5aa0317082b12dffe926781d56 162 SUPERFAMILY SSF53335 5 134 5.4E-7 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_04015 1cafbd5aa0317082b12dffe926781d56 162 Gene3D G3DSA:3.40.50.150 1 161 6.1E-42 T 12-10-2018 THERU_04015 1cafbd5aa0317082b12dffe926781d56 162 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 1 142 9.7E-19 T 12-10-2018 IPR008884 Macrocin-O-methyltransferase THERU_02050 410928b887c89a2433806252d3ca030b 287 SMART SM00475 1 254 1.8E-117 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 THERU_02050 410928b887c89a2433806252d3ca030b 287 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 166 4.4E-49 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 THERU_02050 410928b887c89a2433806252d3ca030b 287 Gene3D G3DSA:1.10.150.20 170 239 3.6E-86 T 12-10-2018 THERU_02050 410928b887c89a2433806252d3ca030b 287 SUPERFAMILY SSF47807 167 279 1.11E-26 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily THERU_02050 410928b887c89a2433806252d3ca030b 287 SUPERFAMILY SSF88723 2 166 3.93E-50 T 12-10-2018 IPR029060 PIN-like domain superfamily THERU_02050 410928b887c89a2433806252d3ca030b 287 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 257 5.2E-22 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 THERU_02050 410928b887c89a2433806252d3ca030b 287 SMART SM00279 169 204 7.3E-15 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 THERU_02050 410928b887c89a2433806252d3ca030b 287 Gene3D G3DSA:3.40.50.1010 4 269 3.6E-86 T 12-10-2018 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SUPERFAMILY SSF50249 613 693 1.3E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 694 9.6E-246 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SUPERFAMILY SSF50249 60 127 4.6E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Pfam PF00575 S1 RNA binding domain 611 691 3.7E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Pfam PF00773 RNB domain 239 565 3.1E-114 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Gene3D G3DSA:2.40.50.140 614 700 4.5E-21 T 12-10-2018 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 688 1.5E-179 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Gene3D G3DSA:2.40.50.140 61 127 6.4E-16 T 12-10-2018 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SUPERFAMILY SSF50249 120 216 3.03E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SMART SM00316 62 124 1.1 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SMART SM00316 611 694 6.7E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SMART SM00955 239 566 2.4E-165 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SUPERFAMILY SSF50249 205 610 2.28E-138 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Hamap MF_01895 Ribonuclease R [rnr]. 22 694 56.516 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 ProSitePatterns PS01175 Ribonuclease II family signature. 533 557 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 Pfam PF08206 Ribonuclease B OB domain 69 122 4.9E-15 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain THERU_07585 7362493ef4005c2d9424f91ce2ec65ef 700 SMART SM00357 68 125 1.0E-8 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 THERU_02440 a66b158f315e9690613f60486dd21433 221 PRINTS PR01008 Flagellar L-ring protein signature 182 196 2.9E-11 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 PRINTS PR01008 Flagellar L-ring protein signature 64 76 2.9E-11 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 PRINTS PR01008 Flagellar L-ring protein signature 161 177 2.9E-11 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 PRINTS PR01008 Flagellar L-ring protein signature 198 212 2.9E-11 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 PRINTS PR01008 Flagellar L-ring protein signature 135 150 2.9E-11 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 219 22.451 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_02440 a66b158f315e9690613f60486dd21433 221 Pfam PF02107 Flagellar L-ring protein 44 220 5.2E-44 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THERU_06655 54720adadbf584e87e3e44a134d98509 185 Pfam PF05685 Putative restriction endonuclease 12 165 8.0E-30 T 12-10-2018 IPR008538 Domain of unknown function DUF820 THERU_06655 54720adadbf584e87e3e44a134d98509 185 SUPERFAMILY SSF52980 5 181 4.45E-38 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THERU_06655 54720adadbf584e87e3e44a134d98509 185 Gene3D G3DSA:3.90.1570.10 2 183 1.8E-41 T 12-10-2018 THERU_06500 44ad7ac5fc57593a318c95c5a35c89eb 290 SUPERFAMILY SSF47323 88 287 2.83E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06500 44ad7ac5fc57593a318c95c5a35c89eb 290 Pfam PF08264 Anticodon-binding domain of tRNA 128 250 1.5E-21 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THERU_06500 44ad7ac5fc57593a318c95c5a35c89eb 290 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 43 84 2.3E-8 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_06500 44ad7ac5fc57593a318c95c5a35c89eb 290 Gene3D G3DSA:1.10.730.10 25 287 1.9E-84 T 12-10-2018 THERU_06500 44ad7ac5fc57593a318c95c5a35c89eb 290 SUPERFAMILY SSF52374 43 95 6.22E-15 T 12-10-2018 THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 SUPERFAMILY SSF55129 1 59 9.03E-16 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 58 2.0E-17 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 16.769 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 Gene3D G3DSA:3.30.1390.20 1 60 7.1E-20 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 2.0E-12 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THERU_01485 69709a3b082d2e6d489dbd0645a9ea42 64 PIRSF PIRSF002211 1 60 5.4E-21 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01310 32896c402b46bec4a0444eb409a87879 269 Gene3D G3DSA:3.30.930.10 15 240 3.3E-31 T 12-10-2018 THERU_01310 32896c402b46bec4a0444eb409a87879 269 SUPERFAMILY SSF55681 23 231 1.63E-35 T 12-10-2018 THERU_00695 7d0310f9afea23a0dc951e57fe1cf46f 252 Pfam PF01351 Ribonuclease HII 75 227 1.1E-19 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain THERU_00695 7d0310f9afea23a0dc951e57fe1cf46f 252 Gene3D G3DSA:3.30.310.10 1 69 1.9E-17 T 12-10-2018 IPR012295 TBP domain superfamily THERU_00695 7d0310f9afea23a0dc951e57fe1cf46f 252 Gene3D G3DSA:3.30.420.10 73 252 1.2E-48 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THERU_00695 7d0310f9afea23a0dc951e57fe1cf46f 252 SUPERFAMILY SSF53098 74 225 1.82E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 Gene3D G3DSA:1.20.81.30 57 176 2.6E-35 T 12-10-2018 THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 69 81 3.6E-16 T 12-10-2018 IPR003004 GspF/PilC family THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 3.6E-16 T 12-10-2018 IPR003004 GspF/PilC family THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 3.6E-16 T 12-10-2018 IPR003004 GspF/PilC family THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 3.6E-16 T 12-10-2018 IPR003004 GspF/PilC family THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 Gene3D G3DSA:1.20.81.30 260 370 2.3E-27 T 12-10-2018 THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 Pfam PF00482 Type II secretion system (T2SS), protein F 277 399 1.4E-31 T 12-10-2018 IPR018076 Type II secretion system F domain THERU_02990 322c19fe0ee20b81e0dff0faa13f5b46 409 Pfam PF00482 Type II secretion system (T2SS), protein F 73 196 1.3E-34 T 12-10-2018 IPR018076 Type II secretion system F domain THERU_01925 0b355be60ffd4ae0037b45dd5887b082 171 Pfam PF01724 Domain of unknown function DUF29 11 165 3.0E-39 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_01925 0b355be60ffd4ae0037b45dd5887b082 171 Gene3D G3DSA:1.20.1220.20 5 169 1.8E-22 T 12-10-2018 THERU_08235 c1ad5875033147809a4f3d6bf0d9b523 102 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 9 96 1.1E-22 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THERU_08235 c1ad5875033147809a4f3d6bf0d9b523 102 Gene3D G3DSA:3.30.1360.20 8 101 1.2E-23 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THERU_08235 c1ad5875033147809a4f3d6bf0d9b523 102 SUPERFAMILY SSF55248 13 98 3.4E-23 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THERU_01555 ac18ab8c8834d0487384c8c42bde3c1d 129 Gene3D G3DSA:3.40.120.10 5 124 2.4E-28 T 12-10-2018 THERU_02290 7456d1a40d46875e230fc977effb43ae 325 PIRSF PIRSF006655 1 59 0.017 T 12-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 THERU_02290 7456d1a40d46875e230fc977effb43ae 325 PIRSF PIRSF006655 47 325 7.1E-126 T 12-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 THERU_02290 7456d1a40d46875e230fc977effb43ae 325 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 11 324 4.0E-135 T 12-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 THERU_02290 7456d1a40d46875e230fc977effb43ae 325 Hamap MF_01244 3-dehydroquinate synthase [aroB']. 1 325 39.271 T 12-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 THERU_02290 7456d1a40d46875e230fc977effb43ae 325 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 2 325 7.5E-126 T 12-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 THERU_06785 c33eeacc07102ba22d83bc426bae16e2 227 SUPERFAMILY SSF50156 128 225 3.15E-15 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 THERU_06785 c33eeacc07102ba22d83bc426bae16e2 227 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 54 225 1.0E-29 T 12-10-2018 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 THERU_06785 c33eeacc07102ba22d83bc426bae16e2 227 Gene3D G3DSA:2.30.42.10 125 225 1.9E-19 T 12-10-2018 THERU_06755 2e5984ea75d97c31cb964825e51766bd 84 Pfam PF13937 Domain of unknown function (DUF4212) 7 82 6.1E-30 T 12-10-2018 IPR019886 Sodium symporter small subunit, predicted THERU_06755 2e5984ea75d97c31cb964825e51766bd 84 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 9 83 9.8E-31 T 12-10-2018 IPR019886 Sodium symporter small subunit, predicted THERU_01115 50c352b0522b21797ce334dbc9121131 549 Gene3D G3DSA:3.40.50.300 354 538 4.6E-19 T 12-10-2018 THERU_01115 50c352b0522b21797ce334dbc9121131 549 SUPERFAMILY SSF52540 122 530 1.21E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02135 af8a4982b3879e473eef121ac15ca2c4 146 SUPERFAMILY SSF46458 26 144 1.07E-24 T 12-10-2018 IPR009050 Globin-like superfamily THERU_02135 af8a4982b3879e473eef121ac15ca2c4 146 Gene3D G3DSA:1.10.490.10 16 146 4.8E-39 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 THERU_02135 af8a4982b3879e473eef121ac15ca2c4 146 Pfam PF01152 Bacterial-like globin 27 141 1.7E-14 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 THERU_03580 f835f668e6f489a59ab2ebc919226643 129 Gene3D G3DSA:3.10.129.10 1 129 8.2E-42 T 12-10-2018 THERU_03580 f835f668e6f489a59ab2ebc919226643 129 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 109 4.5E-10 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 THERU_03580 f835f668e6f489a59ab2ebc919226643 129 SUPERFAMILY SSF54637 13 119 7.75E-27 T 12-10-2018 IPR029069 HotDog domain superfamily THERU_03580 f835f668e6f489a59ab2ebc919226643 129 Pfam PF03061 Thioesterase superfamily 42 111 3.2E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THERU_01180 695a75370986f2f7a1e66af06f3d5aee 147 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 2 117 2.0E-9 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THERU_01395 9be8b2545090138b33a969859a53fd53 208 Pfam PF07314 Protein of unknown function (DUF1461) 5 178 8.2E-22 T 12-10-2018 IPR010178 Integral membrane protein 1906 THERU_01395 9be8b2545090138b33a969859a53fd53 208 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 4 193 5.5E-26 T 12-10-2018 IPR010178 Integral membrane protein 1906 THERU_07485 5e05349fb427ac74384270e0f1218b7f 146 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THERU_07485 5e05349fb427ac74384270e0f1218b7f 146 Gene3D G3DSA:2.40.50.100 6 137 4.6E-34 T 12-10-2018 THERU_07485 5e05349fb427ac74384270e0f1218b7f 146 Pfam PF01597 Glycine cleavage H-protein 13 135 8.3E-42 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THERU_07485 5e05349fb427ac74384270e0f1218b7f 146 SUPERFAMILY SSF51230 10 133 3.66E-31 T 12-10-2018 IPR011053 Single hybrid motif THERU_07485 5e05349fb427ac74384270e0f1218b7f 146 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 138 31.61 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THERU_04810 9357192e4549eb7e4781493889ec2647 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.8E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_04810 9357192e4549eb7e4781493889ec2647 197 SUPERFAMILY SSF48498 81 196 4.63E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily THERU_04810 9357192e4549eb7e4781493889ec2647 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_04810 9357192e4549eb7e4781493889ec2647 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THERU_04810 9357192e4549eb7e4781493889ec2647 197 Gene3D G3DSA:1.10.357.10 2 197 1.2E-31 T 12-10-2018 THERU_04810 9357192e4549eb7e4781493889ec2647 197 SUPERFAMILY SSF46689 3 82 2.59E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 Pfam PF00281 Ribosomal protein L5 31 87 2.3E-26 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.119 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 Pfam PF00673 ribosomal L5P family C-terminus 91 183 2.4E-38 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 PIRSF PIRSF002161 5 186 4.2E-64 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 SUPERFAMILY SSF55282 10 185 3.06E-75 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_01455 afd74044c23e51cb0f3f8338a54cff63 187 Gene3D G3DSA:3.30.1440.10 7 186 9.7E-78 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_03945 ed82aa879c67133db86cfb2af88144eb 139 Pfam PF02566 OsmC-like protein 33 132 1.9E-11 T 12-10-2018 IPR003718 OsmC/Ohr family THERU_03945 ed82aa879c67133db86cfb2af88144eb 139 SUPERFAMILY SSF82784 1 138 2.09E-25 T 12-10-2018 IPR036102 OsmC/Ohr superfamily THERU_03945 ed82aa879c67133db86cfb2af88144eb 139 Gene3D G3DSA:3.30.300.20 1 138 5.0E-22 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_02640 32c9b2d9f7c0938172c24c6618a239f8 514 Gene3D G3DSA:3.30.200.210 9 130 3.9E-9 T 12-10-2018 THERU_02640 32c9b2d9f7c0938172c24c6618a239f8 514 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 16 66 8.4E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02640 32c9b2d9f7c0938172c24c6618a239f8 514 SMART SM00926 14 69 6.0E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02640 32c9b2d9f7c0938172c24c6618a239f8 514 SUPERFAMILY SSF53706 16 370 8.73E-26 T 12-10-2018 THERU_02640 32c9b2d9f7c0938172c24c6618a239f8 514 Gene3D G3DSA:3.40.50.740 272 377 8.9E-6 T 12-10-2018 THERU_06675 c22fc23b6c127f097912c38e76eb0b0e 253 SUPERFAMILY SSF56281 4 253 1.0E-36 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_06675 c22fc23b6c127f097912c38e76eb0b0e 253 Gene3D G3DSA:3.60.15.10 4 253 9.8E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THERU_06675 c22fc23b6c127f097912c38e76eb0b0e 253 Pfam PF12706 Beta-lactamase superfamily domain 35 217 2.2E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase THERU_02945 2afc998328e8e910188c4480fba9bebf 260 Gene3D G3DSA:3.40.50.720 1 98 7.4E-13 T 12-10-2018 THERU_02945 2afc998328e8e910188c4480fba9bebf 260 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 97 1.2E-10 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 THERU_02945 2afc998328e8e910188c4480fba9bebf 260 SUPERFAMILY SSF51735 1 147 9.44E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_05915 5d41c10e077c6c2c16ca238c7b778676 391 Gene3D G3DSA:3.30.450.40 148 285 2.4E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily THERU_06460 21ee02508f048076dbd79eedf5119623 280 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 33 239 3.5E-79 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 THERU_06460 21ee02508f048076dbd79eedf5119623 280 Gene3D G3DSA:3.40.1750.20 129 196 8.3E-77 T 12-10-2018 THERU_06460 21ee02508f048076dbd79eedf5119623 280 Gene3D G3DSA:3.90.226.10 34 235 8.3E-77 T 12-10-2018 THERU_06460 21ee02508f048076dbd79eedf5119623 280 Pfam PF01343 Peptidase family S49 88 240 3.8E-52 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THERU_06460 21ee02508f048076dbd79eedf5119623 280 SUPERFAMILY SSF52096 11 226 2.07E-41 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_00185 9ade07128d27dedc8f8f8efd6082ad32 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_00185 9ade07128d27dedc8f8f8efd6082ad32 252 Gene3D G3DSA:1.10.1060.10 43 143 7.4E-10 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_00185 9ade07128d27dedc8f8f8efd6082ad32 252 SUPERFAMILY SSF46548 58 140 1.5E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THERU_00185 9ade07128d27dedc8f8f8efd6082ad32 252 Pfam PF13534 4Fe-4S dicluster domain 63 124 7.0E-11 T 12-10-2018 THERU_00185 9ade07128d27dedc8f8f8efd6082ad32 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 SMART SM00729 39 260 6.6E-14 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 SUPERFAMILY SSF47781 276 351 3.0E-12 T 12-10-2018 IPR010994 RuvA domain 2-like THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 Gene3D G3DSA:1.10.150.320 282 350 1.2E-8 T 12-10-2018 THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 Pfam PF04055 Radical SAM superfamily 46 215 1.3E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 Pfam PF12836 Helix-hairpin-helix motif 296 343 8.7E-9 T 12-10-2018 THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 Gene3D G3DSA:3.20.20.70 40 255 2.0E-25 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02315 5c6e1252b6194e284fb3f2f0de15ce5d 360 SUPERFAMILY SSF102114 27 261 5.76E-26 T 12-10-2018 THERU_00170 934bfef46238d265a9d9d88a7098e619 454 Pfam PF02754 Cysteine-rich domain 238 336 2.1E-11 T 12-10-2018 IPR004017 Cysteine-rich domain THERU_06775 b9e12134a25c041bcea7a788df54710e 439 SUPERFAMILY SSF63825 291 389 3.4E-7 T 12-10-2018 THERU_06775 b9e12134a25c041bcea7a788df54710e 439 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 75 109 6.7E-7 T 12-10-2018 IPR013378 Listeria/Bacterioides repeat THERU_06380 f0579d6ec828e28f48b735329bdbd379 510 Gene3D G3DSA:3.40.50.300 1 224 5.4E-30 T 12-10-2018 THERU_06380 f0579d6ec828e28f48b735329bdbd379 510 PIRSF PIRSF003128 1 508 4.1E-99 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THERU_06380 f0579d6ec828e28f48b735329bdbd379 510 SUPERFAMILY SSF52540 1 479 2.09E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06380 f0579d6ec828e28f48b735329bdbd379 510 Gene3D G3DSA:3.40.50.300 229 506 2.6E-28 T 12-10-2018 THERU_06380 f0579d6ec828e28f48b735329bdbd379 510 Pfam PF02463 RecF/RecN/SMC N terminal domain 63 469 4.6E-11 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal THERU_03585 7bc059f04f40300cd290d8758e2f4c68 125 Pfam PF04314 Copper chaperone PCu(A)C 3 107 3.4E-41 T 12-10-2018 IPR007410 Copper chaperone PCuAC THERU_03585 7bc059f04f40300cd290d8758e2f4c68 125 Gene3D G3DSA:2.60.40.1890 7 117 3.5E-40 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily THERU_03585 7bc059f04f40300cd290d8758e2f4c68 125 SUPERFAMILY SSF110087 1 114 6.54E-44 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily THERU_05740 2c9ad99e5e8eb7e2a581e80ca4d92420 90 Gene3D G3DSA:3.90.20.10 14 87 1.2E-11 T 12-10-2018 THERU_05740 2c9ad99e5e8eb7e2a581e80ca4d92420 90 SUPERFAMILY SSF58064 24 69 3.89E-6 T 12-10-2018 THERU_08440 6a78df219907017fece94d3ff9887bb2 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 36 413 2.9E-92 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THERU_08440 6a78df219907017fece94d3ff9887bb2 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 301 320 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THERU_08440 6a78df219907017fece94d3ff9887bb2 418 SUPERFAMILY SSF53659 13 418 2.69E-119 T 12-10-2018 THERU_08440 6a78df219907017fece94d3ff9887bb2 418 SMART SM01329 35 414 4.4E-141 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THERU_08440 6a78df219907017fece94d3ff9887bb2 418 Gene3D G3DSA:3.40.718.10 5 418 5.3E-141 T 12-10-2018 THERU_06180 c57bbdbbcb401ec0ee11c9dace00a2f3 218 Pfam PF01694 Rhomboid family 56 214 6.8E-40 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THERU_06180 c57bbdbbcb401ec0ee11c9dace00a2f3 218 Gene3D G3DSA:1.20.1540.10 10 217 1.9E-33 T 12-10-2018 IPR035952 Rhomboid-like superfamily THERU_06180 c57bbdbbcb401ec0ee11c9dace00a2f3 218 SUPERFAMILY SSF144091 10 215 5.62E-43 T 12-10-2018 THERU_00360 57072bd85f584e4e7ee6008d5bcf5994 161 PIRSF PIRSF005028 1 160 9.3E-54 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT THERU_00360 57072bd85f584e4e7ee6008d5bcf5994 161 SUPERFAMILY SSF116726 81 157 2.88E-19 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THERU_00360 57072bd85f584e4e7ee6008d5bcf5994 161 Gene3D G3DSA:3.30.70.1450 82 159 8.8E-23 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THERU_00360 57072bd85f584e4e7ee6008d5bcf5994 161 Pfam PF02080 TrkA-C domain 86 156 9.3E-17 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THERU_03525 1d7784b3031c4ea422772b65adde1ee7 422 SUPERFAMILY SSF50969 34 398 1.49E-31 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THERU_03525 1d7784b3031c4ea422772b65adde1ee7 422 Gene3D G3DSA:2.130.10.10 31 236 1.0E-24 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THERU_03525 1d7784b3031c4ea422772b65adde1ee7 422 Gene3D G3DSA:2.130.10.10 237 408 4.9E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THERU_03525 1d7784b3031c4ea422772b65adde1ee7 422 Pfam PF02239 Cytochrome D1 heme domain 34 207 2.0E-11 T 12-10-2018 THERU_01690 d6e00755ed7e36e1899ed07991ce753e 236 SUPERFAMILY SSF53335 3 190 4.51E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_01690 d6e00755ed7e36e1899ed07991ce753e 236 Gene3D G3DSA:3.40.50.150 7 234 2.2E-43 T 12-10-2018 THERU_01690 d6e00755ed7e36e1899ed07991ce753e 236 Pfam PF05175 Methyltransferase small domain 30 158 1.4E-12 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 THERU_01690 d6e00755ed7e36e1899ed07991ce753e 236 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THERU_05820 c8a7420e160f16b2c48786f87a1a37c0 201 SUPERFAMILY SSF52540 2 190 1.45E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05820 c8a7420e160f16b2c48786f87a1a37c0 201 Pfam PF01121 Dephospho-CoA kinase 4 178 3.0E-39 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THERU_05820 c8a7420e160f16b2c48786f87a1a37c0 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 186 3.7E-41 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THERU_05820 c8a7420e160f16b2c48786f87a1a37c0 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 195 22.686 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THERU_05820 c8a7420e160f16b2c48786f87a1a37c0 201 Gene3D G3DSA:3.40.50.300 1 196 4.8E-63 T 12-10-2018 THERU_07890 8d5a0e827a916c9bd3ddc9c432ccf8f2 138 SUPERFAMILY SSF102712 1 133 1.44E-30 T 12-10-2018 THERU_07890 8d5a0e827a916c9bd3ddc9c432ccf8f2 138 Gene3D G3DSA:3.40.140.10 1 137 2.5E-40 T 12-10-2018 THERU_07890 8d5a0e827a916c9bd3ddc9c432ccf8f2 138 SMART SM00232 1 134 3.3E-28 T 12-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 THERU_07890 8d5a0e827a916c9bd3ddc9c432ccf8f2 138 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 123 7.0E-26 T 12-10-2018 IPR028090 JAB domain, prokaryotic THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 SMART SM00535 24 152 7.8E-38 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 Pfam PF00035 Double-stranded RNA binding motif 160 225 6.7E-15 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 SUPERFAMILY SSF69065 8 149 2.09E-41 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 12 224 1.1E-65 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 Pfam PF14622 Ribonuclease-III-like 23 131 2.1E-26 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 SUPERFAMILY SSF54768 111 225 4.87E-24 T 12-10-2018 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 Hamap MF_00104 Ribonuclease 3 [rnc]. 12 222 27.757 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 Gene3D G3DSA:1.10.1520.10 7 157 2.2E-45 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 SMART SM00358 160 226 1.5E-16 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain THERU_06140 173767daf23d4c0c9e010a89b94d211c 228 Gene3D G3DSA:3.30.160.20 158 227 2.8E-22 T 12-10-2018 THERU_05995 64e2db264a1a68f368fdf843e51bcdf3 371 SUPERFAMILY SSF102114 46 270 4.84E-26 T 12-10-2018 THERU_05995 64e2db264a1a68f368fdf843e51bcdf3 371 Gene3D G3DSA:3.20.20.70 32 286 1.1E-18 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_05995 64e2db264a1a68f368fdf843e51bcdf3 371 SMART SM00729 45 265 1.4E-20 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THERU_05995 64e2db264a1a68f368fdf843e51bcdf3 371 Pfam PF04055 Radical SAM superfamily 53 225 4.1E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_00105 ab5ea2c657f599cf583f9a3542c2e151 143 SUPERFAMILY SSF46785 4 132 1.64E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THERU_00105 ab5ea2c657f599cf583f9a3542c2e151 143 Gene3D G3DSA:1.10.10.10 1 142 5.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THERU_00105 ab5ea2c657f599cf583f9a3542c2e151 143 Pfam PF02082 Transcriptional regulator 1 80 1.1E-22 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type THERU_00105 ab5ea2c657f599cf583f9a3542c2e151 143 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 5.2E-37 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type THERU_00105 ab5ea2c657f599cf583f9a3542c2e151 143 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site THERU_05710 4f35145d466a1b29edb22648a3075e90 192 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 88 99 - T 12-10-2018 IPR018215 ClpP, Ser active site THERU_05710 4f35145d466a1b29edb22648a3075e90 192 SUPERFAMILY SSF52096 8 190 4.21E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_05710 4f35145d466a1b29edb22648a3075e90 192 Gene3D G3DSA:3.90.226.10 1 192 4.4E-85 T 12-10-2018 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 3.9E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 PRINTS PR00127 Clp protease catalytic subunit P signature 166 185 3.9E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 3.9E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 3.9E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 PRINTS PR00127 Clp protease catalytic subunit P signature 109 128 3.9E-54 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 110 123 - T 12-10-2018 IPR033135 ClpP, histidine active site THERU_05710 4f35145d466a1b29edb22648a3075e90 192 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 190 2.0E-103 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 191 45.584 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THERU_05710 4f35145d466a1b29edb22648a3075e90 192 Pfam PF00574 Clp protease 11 190 1.1E-89 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THERU_05950 c09a1c2d178c8d5df6c66615a0c33a49 153 Gene3D G3DSA:3.90.1010.10 1 137 4.5E-59 T 12-10-2018 THERU_05950 c09a1c2d178c8d5df6c66615a0c33a49 153 Pfam PF01592 NifU-like N terminal domain 3 125 4.0E-52 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 THERU_05950 c09a1c2d178c8d5df6c66615a0c33a49 153 SUPERFAMILY SSF82649 6 128 4.71E-42 T 12-10-2018 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 SMART SM00863 168 217 3.5E-25 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 68 628 1.1E-219 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 SUPERFAMILY SSF55681 241 526 6.84E-98 T 12-10-2018 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Gene3D G3DSA:3.30.54.20 129 185 2.1E-59 T 12-10-2018 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 SUPERFAMILY SSF55186 60 239 2.49E-59 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 168 217 1.1E-15 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 323 529 6.8E-40 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 1.3E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 1.3E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 1.3E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 1.3E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 1.3E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Gene3D G3DSA:3.30.980.10 65 220 2.1E-59 T 12-10-2018 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 62 634 34.802 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Pfam PF03129 Anticodon binding domain 541 630 1.6E-22 T 12-10-2018 IPR004154 Anticodon-binding THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Gene3D G3DSA:3.40.50.800 532 637 2.7E-35 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 Gene3D G3DSA:3.30.930.10 221 531 1.9E-124 T 12-10-2018 THERU_02200 1a2798f53ca1914fc8eaf80adae33cf3 637 SUPERFAMILY SSF52954 529 633 5.29E-32 T 12-10-2018 THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 4.8E-110 T 12-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 241 1.2E-53 T 12-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 2.6E-24 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 Pfam PF00460 Flagella basal body rod protein 5 35 7.8E-12 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 SUPERFAMILY SSF117143 93 222 1.44E-38 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 243 5.3E-33 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G THERU_00430 d3c3c2e60c7f0b9afeae65c32fde0fd7 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 1.4E-51 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G THERU_05240 de66944ca2d589197ed870737afe9fb6 543 Gene3D G3DSA:3.90.1640.30 52 316 6.9E-74 T 12-10-2018 THERU_05240 de66944ca2d589197ed870737afe9fb6 543 Pfam PF02272 DHHA1 domain 313 430 3.5E-15 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THERU_05240 de66944ca2d589197ed870737afe9fb6 543 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 479 5.9E-125 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 THERU_05240 de66944ca2d589197ed870737afe9fb6 543 Gene3D G3DSA:3.10.310.30 317 436 7.8E-25 T 12-10-2018 THERU_05240 de66944ca2d589197ed870737afe9fb6 543 SUPERFAMILY SSF64182 51 435 1.83E-86 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily THERU_05240 de66944ca2d589197ed870737afe9fb6 543 Pfam PF01368 DHH family 77 174 2.6E-7 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THERU_05505 84b07ed6f0b93778d5da0c7548671b19 342 SUPERFAMILY SSF52540 93 339 2.9E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05505 84b07ed6f0b93778d5da0c7548671b19 342 ProSitePatterns PS01215 Mrp family signature. 199 215 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 THERU_05505 84b07ed6f0b93778d5da0c7548671b19 342 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 91 334 1.9E-103 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 THERU_05505 84b07ed6f0b93778d5da0c7548671b19 342 Gene3D G3DSA:3.40.50.300 79 333 3.1E-88 T 12-10-2018 THERU_05505 84b07ed6f0b93778d5da0c7548671b19 342 Hamap MF_02040 Iron-sulfur cluster carrier protein. 86 336 39.088 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 TIGRFAM TIGR00077 lspA: signal peptidase II 6 159 2.4E-29 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 7 159 13.971 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 134 150 2.7E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 51 59 2.7E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 98 113 2.7E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 ProSitePatterns PS00855 Signal peptidases II signature. 101 113 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_06975 ff9b9b75f89b46cda4e0873e849f8748 163 Pfam PF01252 Signal peptidase (SPase) II 16 153 9.8E-31 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THERU_00780 39ebcaedaaa56ba871d4ab7890437959 192 Gene3D G3DSA:3.40.50.150 1 190 1.1E-73 T 12-10-2018 THERU_00780 39ebcaedaaa56ba871d4ab7890437959 192 Pfam PF08241 Methyltransferase domain 39 137 6.7E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THERU_00780 39ebcaedaaa56ba871d4ab7890437959 192 SUPERFAMILY SSF53335 20 190 1.7E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_02980 5de4af01d4139e9ad3e4f0d6a468d73c 404 Gene3D G3DSA:2.40.160.60 20 404 1.7E-74 T 12-10-2018 THERU_02980 5de4af01d4139e9ad3e4f0d6a468d73c 404 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 24 314 1.2E-29 T 12-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THERU_02980 5de4af01d4139e9ad3e4f0d6a468d73c 404 SUPERFAMILY SSF56935 21 404 2.27E-67 T 12-10-2018 THERU_07465 4f34b26da3c380d424d881dce1b5d984 271 Pfam PF00899 ThiF family 12 248 5.3E-71 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THERU_07465 4f34b26da3c380d424d881dce1b5d984 271 SUPERFAMILY SSF69572 3 263 4.45E-100 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 THERU_07465 4f34b26da3c380d424d881dce1b5d984 271 TIGRFAM TIGR02356 adenyl_thiF: thiazole biosynthesis adenylyltransferase ThiF 11 216 3.5E-83 T 12-10-2018 IPR012731 Thiazole biosynthesis adenylyltransferase ThiF KEGG: 00730+2.7.7.73|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THERU_07465 4f34b26da3c380d424d881dce1b5d984 271 Gene3D G3DSA:3.40.50.720 4 257 2.2E-97 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 188 9.7E-78 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 3 17 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 100 108 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 120 132 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 75 86 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 166 179 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00097 Anthranilate synthase component II signature 48 57 5.8E-36 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 3.0E-7 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 3.0E-7 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 1.7E-13 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.7E-13 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.7E-13 T 12-10-2018 THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 Pfam PF00117 Glutamine amidotransferase class-I 5 188 1.0E-54 T 12-10-2018 IPR017926 Glutamine amidotransferase THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 Gene3D G3DSA:3.40.50.880 1 192 8.3E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_00040 ff12d79d3646f579b1d52be383e5f8b9 197 SUPERFAMILY SSF52317 1 193 3.25E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like THERU_00145 4c13074c5e3f8c73f03dddf2fcad0ee7 315 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 54 256 7.2E-33 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 THERU_00145 4c13074c5e3f8c73f03dddf2fcad0ee7 315 SUPERFAMILY SSF53335 5 313 2.97E-58 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_00145 4c13074c5e3f8c73f03dddf2fcad0ee7 315 Gene3D G3DSA:3.40.50.12710 3 315 3.8E-60 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 THERU_01510 63b12f3639456f362bdea12776daa09f 79 SMART SM00316 12 78 1.8E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 THERU_01510 63b12f3639456f362bdea12776daa09f 79 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 9 79 24.719 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THERU_01510 63b12f3639456f362bdea12776daa09f 79 Pfam PF01176 Translation initiation factor 1A / IF-1 18 78 1.6E-28 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 THERU_01510 63b12f3639456f362bdea12776daa09f 79 SUPERFAMILY SSF50249 11 78 3.8E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold THERU_01510 63b12f3639456f362bdea12776daa09f 79 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 11 78 1.4E-35 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THERU_01510 63b12f3639456f362bdea12776daa09f 79 Gene3D G3DSA:2.40.50.140 10 78 3.4E-35 T 12-10-2018 THERU_04165 1ae227ff7474588e1621c24dd780c424 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 2.7E-12 T 12-10-2018 THERU_04165 1ae227ff7474588e1621c24dd780c424 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 258 273 2.7E-12 T 12-10-2018 THERU_04165 1ae227ff7474588e1621c24dd780c424 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.7E-12 T 12-10-2018 THERU_04165 1ae227ff7474588e1621c24dd780c424 347 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 8 293 1.5E-53 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 THERU_04165 1ae227ff7474588e1621c24dd780c424 347 SUPERFAMILY SSF51905 5 331 2.53E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04165 1ae227ff7474588e1621c24dd780c424 347 Gene3D G3DSA:3.50.50.60 1 344 1.7E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04165 1ae227ff7474588e1621c24dd780c424 347 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 44 5.2E-6 T 12-10-2018 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 2 146 8.7E-48 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 SUPERFAMILY SSF53163 1 157 3.4E-47 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 Gene3D G3DSA:3.40.50.1450 1 159 9.8E-48 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 PRINTS PR00446 Hydrogen uptake protein signature 54 64 6.6E-25 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 PRINTS PR00446 Hydrogen uptake protein signature 1 13 6.6E-25 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 PRINTS PR00446 Hydrogen uptake protein signature 33 50 6.6E-25 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 PRINTS PR00446 Hydrogen uptake protein signature 13 24 6.6E-25 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 PRINTS PR00446 Hydrogen uptake protein signature 65 81 6.6E-25 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 1 149 5.4E-53 T 12-10-2018 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 THERU_04865 4d66f47f220c0fb693c3fe1cc9d15be1 164 Pfam PF01750 Hydrogenase maturation protease 18 144 5.8E-36 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THERU_03835 6860e728af7d740ae9601292615b3f84 516 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 465 515 2.5E-9 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THERU_03835 6860e728af7d740ae9601292615b3f84 516 Pfam PF07196 Flagellin hook IN motif 327 379 5.3E-6 T 12-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 THERU_03835 6860e728af7d740ae9601292615b3f84 516 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 515 2.9E-74 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THERU_03835 6860e728af7d740ae9601292615b3f84 516 SUPERFAMILY SSF64518 156 516 2.62E-17 T 12-10-2018 THERU_03835 6860e728af7d740ae9601292615b3f84 516 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 4.2E-5 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THERU_03835 6860e728af7d740ae9601292615b3f84 516 PRINTS PR01005 Flagellar hook-associated protein signature 150 174 4.2E-5 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THERU_03835 6860e728af7d740ae9601292615b3f84 516 PRINTS PR01005 Flagellar hook-associated protein signature 117 137 4.2E-5 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THERU_03835 6860e728af7d740ae9601292615b3f84 516 PRINTS PR01005 Flagellar hook-associated protein signature 482 506 4.2E-5 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THERU_03770 b5e1dd49bb8d77d8803494b539c4abe2 68 Gene3D G3DSA:3.10.20.30 1 68 2.7E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_03770 b5e1dd49bb8d77d8803494b539c4abe2 68 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 68 4.5E-23 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis THERU_03770 b5e1dd49bb8d77d8803494b539c4abe2 68 SUPERFAMILY SSF54285 1 68 5.52E-19 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THERU_03770 b5e1dd49bb8d77d8803494b539c4abe2 68 Pfam PF02597 ThiS family 7 68 9.8E-16 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THERU_04250 14fdbf8ed455310b63694ea6d252157a 78 Pfam PF02597 ThiS family 5 78 1.2E-16 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THERU_04250 14fdbf8ed455310b63694ea6d252157a 78 Gene3D G3DSA:3.10.20.30 1 78 1.6E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily THERU_04250 14fdbf8ed455310b63694ea6d252157a 78 SUPERFAMILY SSF54285 1 78 2.99E-19 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THERU_04250 14fdbf8ed455310b63694ea6d252157a 78 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 78 5.9E-22 T 12-10-2018 THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 Gene3D G3DSA:3.90.1140.10 2 184 1.2E-46 T 12-10-2018 THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 2 183 3.1E-42 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 SUPERFAMILY SSF55144 3 184 2.27E-41 T 12-10-2018 IPR009097 Cyclic phosphodiesterase THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 Pfam PF02834 LigT like Phosphoesterase 12 91 2.0E-15 T 12-10-2018 IPR014051 Phosphoesterase, HXTX THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 Pfam PF02834 LigT like Phosphoesterase 93 175 3.1E-12 T 12-10-2018 IPR014051 Phosphoesterase, HXTX THERU_00290 426f68aac9b4995bd43bf48736a93bc7 185 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 183 23.693 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THERU_07000 ffc9619ec0a8879d87401407777b0486 447 Gene3D G3DSA:1.10.286.90 207 232 6.6E-7 T 12-10-2018 THERU_07000 ffc9619ec0a8879d87401407777b0486 447 Pfam PF00083 Sugar (and other) transporter 56 446 1.1E-48 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 THERU_07000 ffc9619ec0a8879d87401407777b0486 447 SUPERFAMILY SSF103473 13 445 6.93E-79 T 12-10-2018 IPR036259 MFS transporter superfamily THERU_07740 3f17b0f3545a641443094e3f643114da 189 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 22 183 1.6E-55 T 12-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 THERU_00270 08c5f2846349f14b6cb65cd305001c29 112 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 71 8.5E-18 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THERU_00270 08c5f2846349f14b6cb65cd305001c29 112 Pfam PF03840 Preprotein translocase SecG subunit 4 70 3.1E-15 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THERU_00270 08c5f2846349f14b6cb65cd305001c29 112 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.2E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THERU_00270 08c5f2846349f14b6cb65cd305001c29 112 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.2E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THERU_08415 5e3ba40da1c5ec9f66cef5812361def8 358 SUPERFAMILY SSF144052 3 354 1.14E-47 T 12-10-2018 THERU_05135 852ae9a7d5029a150ab7bd7fbf9fba8d 362 Pfam PF06114 IrrE N-terminal-like domain 160 276 2.3E-9 T 12-10-2018 IPR010359 IrrE N-terminal-like domain THERU_05135 852ae9a7d5029a150ab7bd7fbf9fba8d 362 SUPERFAMILY SSF47413 2 71 1.96E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THERU_05135 852ae9a7d5029a150ab7bd7fbf9fba8d 362 Pfam PF12844 Helix-turn-helix domain 8 65 1.8E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THERU_05135 852ae9a7d5029a150ab7bd7fbf9fba8d 362 SMART SM00530 10 65 7.7E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THERU_05135 852ae9a7d5029a150ab7bd7fbf9fba8d 362 Gene3D G3DSA:1.10.260.40 2 66 6.0E-15 T 12-10-2018 THERU_05730 037f076f4848b579e943a7099a114fa4 367 Gene3D G3DSA:3.40.50.2000 165 347 2.0E-60 T 12-10-2018 THERU_05730 037f076f4848b579e943a7099a114fa4 367 Gene3D G3DSA:3.40.50.2000 23 359 2.0E-60 T 12-10-2018 THERU_05730 037f076f4848b579e943a7099a114fa4 367 SUPERFAMILY SSF53756 6 364 7.14E-71 T 12-10-2018 THERU_05730 037f076f4848b579e943a7099a114fa4 367 Pfam PF00534 Glycosyl transferases group 1 180 342 4.3E-25 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 THERU_05730 037f076f4848b579e943a7099a114fa4 367 Pfam PF13439 Glycosyltransferase Family 4 15 169 4.9E-17 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THERU_00990 d8ab18303ae73257c22f17ab11c74773 216 Pfam PF00005 ABC transporter 18 164 2.4E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THERU_00990 d8ab18303ae73257c22f17ab11c74773 216 SMART SM00382 27 213 4.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain THERU_00990 d8ab18303ae73257c22f17ab11c74773 216 SUPERFAMILY SSF52540 2 214 1.04E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_00990 d8ab18303ae73257c22f17ab11c74773 216 Gene3D G3DSA:3.40.50.300 1 215 5.7E-67 T 12-10-2018 THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 Pfam PF00266 Aminotransferase class-V 25 327 2.2E-37 T 12-10-2018 IPR000192 Aminotransferase class V domain THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 SUPERFAMILY SSF53383 5 351 4.26E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 181 201 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 Gene3D G3DSA:3.90.1150.10 9 361 9.6E-108 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 Gene3D G3DSA:3.40.640.10 14 254 9.6E-108 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_06365 a239c2b06c6453511212ec17bb8e6587 373 PIRSF PIRSF000524 1 369 2.1E-106 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 THERU_06055 c7a20e834c4a99b3463e252490809a69 327 Gene3D G3DSA:3.30.565.10 196 279 3.5E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_06055 c7a20e834c4a99b3463e252490809a69 327 Gene3D G3DSA:1.10.287.130 142 195 3.5E-15 T 12-10-2018 THERU_06055 c7a20e834c4a99b3463e252490809a69 327 SUPERFAMILY SSF55874 198 310 1.15E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THERU_08410 830622b3883fb1f39cf01ab35acf86f0 515 Pfam PF02470 MlaD protein 37 112 1.5E-18 T 12-10-2018 IPR003399 Mce/MlaD THERU_03260 4ad6077ebaa72129c1f80629a725d31f 168 Pfam PF01569 PAP2 superfamily 59 167 2.4E-24 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THERU_03260 4ad6077ebaa72129c1f80629a725d31f 168 SMART SM00014 58 165 4.1E-19 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THERU_03260 4ad6077ebaa72129c1f80629a725d31f 168 Gene3D G3DSA:1.20.144.10 92 168 5.5E-17 T 12-10-2018 THERU_03260 4ad6077ebaa72129c1f80629a725d31f 168 SUPERFAMILY SSF48317 7 167 1.31E-35 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily THERU_01320 3a888d7763af58b737e126dc8e13c187 279 Pfam PF01841 Transglutaminase-like superfamily 1 112 2.5E-24 T 12-10-2018 IPR002931 Transglutaminase-like THERU_01320 3a888d7763af58b737e126dc8e13c187 279 SMART SM00460 45 115 6.3E-23 T 12-10-2018 IPR002931 Transglutaminase-like THERU_01320 3a888d7763af58b737e126dc8e13c187 279 Gene3D G3DSA:3.10.620.30 1 137 8.2E-20 T 12-10-2018 THERU_01320 3a888d7763af58b737e126dc8e13c187 279 SUPERFAMILY SSF54001 2 167 2.8E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THERU_05110 ce863571a5b6e980e6cb36b69efd5d3d 166 Gene3D G3DSA:1.20.1220.20 5 164 2.4E-25 T 12-10-2018 THERU_05110 ce863571a5b6e980e6cb36b69efd5d3d 166 Pfam PF01724 Domain of unknown function DUF29 11 162 4.7E-41 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 3.9E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 3.9E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 3.9E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 3.9E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 Gene3D G3DSA:1.20.5.1150 16 54 4.6E-15 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 Pfam PF01165 Ribosomal protein S21 4 56 2.8E-21 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 58 3.4E-22 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_00320 75dd815481f5ba0630b8d378412a1baf 66 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.213 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07980 7761c3d1e866993a709a2742d0d5222f 219 Pfam PF08241 Methyltransferase domain 40 119 1.8E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THERU_07980 7761c3d1e866993a709a2742d0d5222f 219 Gene3D G3DSA:3.40.50.150 5 164 5.9E-29 T 12-10-2018 THERU_07980 7761c3d1e866993a709a2742d0d5222f 219 SUPERFAMILY SSF53335 12 171 4.87E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THERU_06570 4219810fda891b21901c305d11d1cd4d 203 Gene3D G3DSA:3.30.420.10 2 201 1.3E-66 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THERU_06570 4219810fda891b21901c305d11d1cd4d 203 Pfam PF01351 Ribonuclease HII 16 188 2.0E-31 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain THERU_06570 4219810fda891b21901c305d11d1cd4d 203 SUPERFAMILY SSF53098 8 193 5.92E-57 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_06570 4219810fda891b21901c305d11d1cd4d 203 Hamap MF_00052_B Ribonuclease HII [rnhB]. 14 191 30.773 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 160 1.3E-69 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 Pfam PF00731 AIR carboxylase 6 151 9.6E-68 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 157 33.015 T 12-10-2018 IPR033747 Class I PurE THERU_02555 98226fadd2dab554d6555a326e7651ed 164 PIRSF PIRSF001338 1 164 4.7E-70 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 SMART SM01001 4 153 1.2E-101 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 SUPERFAMILY SSF52255 5 163 1.19E-67 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 THERU_02555 98226fadd2dab554d6555a326e7651ed 164 Gene3D G3DSA:3.40.50.7700 1 164 9.4E-75 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 THERU_07375 fd014543ddcbf0a32e418974d349c98a 66 SUPERFAMILY SSF46561 1 63 2.75E-17 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07375 fd014543ddcbf0a32e418974d349c98a 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 15.777 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07375 fd014543ddcbf0a32e418974d349c98a 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.2E-15 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07375 fd014543ddcbf0a32e418974d349c98a 66 Pfam PF00831 Ribosomal L29 protein 4 60 1.8E-15 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THERU_07375 fd014543ddcbf0a32e418974d349c98a 66 Gene3D G3DSA:1.10.287.310 1 66 2.7E-18 T 12-10-2018 THERU_02415 02c639111fcbf76771b9d3d551d6e680 168 SUPERFAMILY SSF52833 42 151 1.16E-12 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02415 02c639111fcbf76771b9d3d551d6e680 168 Gene3D G3DSA:3.40.30.10 34 165 2.6E-23 T 12-10-2018 THERU_02415 02c639111fcbf76771b9d3d551d6e680 168 Pfam PF13098 Thioredoxin-like domain 42 142 5.2E-15 T 12-10-2018 IPR012336 Thioredoxin-like fold THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 SUPERFAMILY SSF53901 7 308 2.13E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 69.004 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 307 7.6E-38 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 Gene3D G3DSA:3.40.47.10 3 308 7.5E-127 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 308 2.6E-124 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THERU_07830 1468dd5e1f09957398d2acb5861782f5 308 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 182 1.5E-31 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THERU_07630 5199006f7f3d5cf44afbac9e929b108e 242 Gene3D G3DSA:3.40.50.720 1 241 2.2E-43 T 12-10-2018 THERU_07630 5199006f7f3d5cf44afbac9e929b108e 242 SUPERFAMILY SSF51735 3 237 3.66E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily THERU_07630 5199006f7f3d5cf44afbac9e929b108e 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 236 9.5E-31 T 12-10-2018 THERU_06255 643225326abdc2794688034908d72d4d 146 ProSitePatterns PS00360 Ribosomal protein S9 signature. 85 103 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 THERU_06255 643225326abdc2794688034908d72d4d 146 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 11 146 30.653 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid THERU_06255 643225326abdc2794688034908d72d4d 146 Gene3D G3DSA:3.30.230.10 12 146 1.7E-45 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THERU_06255 643225326abdc2794688034908d72d4d 146 Pfam PF00380 Ribosomal protein S9/S16 20 146 1.4E-41 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 THERU_06255 643225326abdc2794688034908d72d4d 146 SUPERFAMILY SSF54211 16 146 7.97E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_07935 a74814a8c2d4a40da33d0e8081c9a010 364 Pfam PF00149 Calcineurin-like phosphoesterase 143 306 4.3E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THERU_07935 a74814a8c2d4a40da33d0e8081c9a010 364 SUPERFAMILY SSF56300 143 363 5.29E-30 T 12-10-2018 THERU_07935 a74814a8c2d4a40da33d0e8081c9a010 364 Gene3D G3DSA:3.60.21.10 141 331 2.4E-17 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like THERU_08500 024c170dc53eb970f01af28c329e6c9e 336 PRINTS PR00069 Aldo-keto reductase signature 129 147 1.8E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THERU_08500 024c170dc53eb970f01af28c329e6c9e 336 PRINTS PR00069 Aldo-keto reductase signature 170 187 1.8E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THERU_08500 024c170dc53eb970f01af28c329e6c9e 336 Pfam PF00248 Aldo/keto reductase family 14 188 1.3E-23 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain THERU_08500 024c170dc53eb970f01af28c329e6c9e 336 SUPERFAMILY SSF51430 8 326 6.68E-42 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THERU_08500 024c170dc53eb970f01af28c329e6c9e 336 Gene3D G3DSA:3.20.20.100 5 334 7.7E-37 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THERU_00305 cb8149dd2ffafeaeaaf0975ca388d323 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 19 87 6.8E-6 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THERU_00305 cb8149dd2ffafeaeaaf0975ca388d323 144 Gene3D G3DSA:2.30.110.10 1 144 1.3E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 THERU_00305 cb8149dd2ffafeaeaaf0975ca388d323 144 SUPERFAMILY SSF50475 1 107 7.58E-10 T 12-10-2018 THERU_06920 10ed58bc564230fe30662c6ec8203942 249 TIGRFAM TIGR00444 mazG: MazG family protein 10 244 2.3E-86 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG THERU_06920 10ed58bc564230fe30662c6ec8203942 249 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 151 213 1.9E-9 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THERU_06920 10ed58bc564230fe30662c6ec8203942 249 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 97 3.7E-28 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THERU_06920 10ed58bc564230fe30662c6ec8203942 249 SUPERFAMILY SSF101386 3 101 1.62E-24 T 12-10-2018 THERU_06920 10ed58bc564230fe30662c6ec8203942 249 SUPERFAMILY SSF101386 124 222 6.92E-25 T 12-10-2018 THERU_06920 10ed58bc564230fe30662c6ec8203942 249 Gene3D G3DSA:1.10.287.1080 119 247 8.3E-47 T 12-10-2018 THERU_06920 10ed58bc564230fe30662c6ec8203942 249 Gene3D G3DSA:1.10.287.1080 1 118 1.7E-40 T 12-10-2018 THERU_00760 c830d0877a343bc66d52e8f84143adfb 288 Gene3D G3DSA:3.30.2010.10 59 149 1.0E-32 T 12-10-2018 THERU_00760 c830d0877a343bc66d52e8f84143adfb 288 Hamap MF_00188 Protease HtpX [htpX]. 4 280 30.828 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 THERU_00760 c830d0877a343bc66d52e8f84143adfb 288 Pfam PF01435 Peptidase family M48 65 280 9.8E-43 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THERU_03025 00b27a870e8d96afba1f754c0e6cfd9a 208 Gene3D G3DSA:1.20.120.1760 7 205 4.9E-31 T 12-10-2018 THERU_03025 00b27a870e8d96afba1f754c0e6cfd9a 208 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 90 2.9E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_03025 00b27a870e8d96afba1f754c0e6cfd9a 208 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THERU_03375 cd566330be6df32187d044c514a4d302 137 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site THERU_03375 cd566330be6df32187d044c514a4d302 137 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 90 135 3.7E-12 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THERU_03375 cd566330be6df32187d044c514a4d302 137 Pfam PF00460 Flagella basal body rod protein 9 32 3.5E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THERU_03375 cd566330be6df32187d044c514a4d302 137 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 137 2.6E-51 T 12-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 11 178 7.8E-38 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 Gene3D G3DSA:2.40.240.10 4 93 1.2E-13 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 180 4.4E-23 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 16 90 3.0E-5 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 Gene3D G3DSA:2.170.120.20 97 188 2.6E-25 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 181 21.554 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 SUPERFAMILY SSF50715 11 180 7.67E-44 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THERU_03110 a8a04f6465fd01c2d2f7d50694f4c4f6 193 Pfam PF01386 Ribosomal L25p family 8 90 1.0E-14 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THERU_00455 8759d4c7b38c850734b8a93a2dcd1ba2 297 Pfam PF04055 Radical SAM superfamily 77 209 2.9E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THERU_00455 8759d4c7b38c850734b8a93a2dcd1ba2 297 SUPERFAMILY SSF102114 80 289 2.62E-12 T 12-10-2018 THERU_00455 8759d4c7b38c850734b8a93a2dcd1ba2 297 PIRSF PIRSF004869 6 294 4.5E-87 T 12-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THERU_00455 8759d4c7b38c850734b8a93a2dcd1ba2 297 Gene3D G3DSA:3.20.20.70 69 291 3.5E-14 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_00455 8759d4c7b38c850734b8a93a2dcd1ba2 297 Pfam PF13353 4Fe-4S single cluster domain 75 162 5.0E-5 T 12-10-2018 THERU_01275 3dbfb816d1c1bc64c3744ccec547b335 165 Pfam PF02517 CAAX protease self-immunity 74 153 6.8E-8 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 Gene3D G3DSA:2.20.28.120 2 52 2.0E-24 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 SUPERFAMILY SSF57829 4 52 9.77E-20 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 Pfam PF00471 Ribosomal protein L33 7 52 3.8E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 4 52 19.517 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 52 4.5E-22 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_07255 30eaf2c88e5f8460869647fd1d345631 52 ProSitePatterns PS00582 Ribosomal protein L33 signature. 20 39 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01325 275cb76d178a61c5830941b6d8a2cb39 326 Pfam PF11992 Domain of unknown function (DUF3488) 7 303 4.8E-50 T 12-10-2018 IPR021878 Protein of unknown function DUF3488 THERU_04175 0cafeb7b0e165407b12b8686d03ec6ac 144 Gene3D G3DSA:2.60.450.10 15 136 1.4E-23 T 12-10-2018 THERU_04175 0cafeb7b0e165407b12b8686d03ec6ac 144 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 16 134 3.4E-24 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THERU_04175 0cafeb7b0e165407b12b8686d03ec6ac 144 Pfam PF03968 OstA-like protein 21 122 1.0E-23 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal THERU_01060 2cf1bd25af16584d0aa46503573f2e75 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 195 1.3E-56 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THERU_01060 2cf1bd25af16584d0aa46503573f2e75 200 SUPERFAMILY SSF53254 1 200 5.41E-58 T 12-10-2018 IPR029033 Histidine phosphatase superfamily THERU_01060 2cf1bd25af16584d0aa46503573f2e75 200 SMART SM00855 4 157 1.4E-20 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THERU_01060 2cf1bd25af16584d0aa46503573f2e75 200 PIRSF PIRSF000709 1 191 6.7E-7 T 12-10-2018 THERU_01060 2cf1bd25af16584d0aa46503573f2e75 200 Gene3D G3DSA:3.40.50.1240 3 200 6.4E-60 T 12-10-2018 IPR029033 Histidine phosphatase superfamily THERU_06685 c8aee88f359ad7cba68fc1e4e9c5345d 72 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 67 7.9E-14 T 12-10-2018 THERU_06685 c8aee88f359ad7cba68fc1e4e9c5345d 72 SUPERFAMILY SSF54862 4 70 1.94E-10 T 12-10-2018 THERU_06685 c8aee88f359ad7cba68fc1e4e9c5345d 72 Gene3D G3DSA:3.30.70.20 2 71 4.6E-15 T 12-10-2018 THERU_08080 844b12a522dc98b3c8fdf511ab8df165 172 Pfam PF01724 Domain of unknown function DUF29 11 162 6.7E-40 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_08080 844b12a522dc98b3c8fdf511ab8df165 172 Gene3D G3DSA:1.20.1220.20 5 172 6.5E-25 T 12-10-2018 THERU_01805 9975df99b16796c3008842dbe6613f26 80 SUPERFAMILY SSF55021 4 74 1.83E-15 T 12-10-2018 THERU_01805 9975df99b16796c3008842dbe6613f26 80 Gene3D G3DSA:3.30.70.260 4 76 1.5E-11 T 12-10-2018 THERU_01805 9975df99b16796c3008842dbe6613f26 80 SMART SM00930 2 73 7.9E-12 T 12-10-2018 IPR018449 NIL domain THERU_01805 9975df99b16796c3008842dbe6613f26 80 Pfam PF09383 NIL domain 5 70 1.3E-13 T 12-10-2018 IPR018449 NIL domain THERU_01430 4a8d579ef5d26537394fccdab2081416 168 Gene3D G3DSA:1.20.1220.20 5 166 6.2E-20 T 12-10-2018 THERU_01430 4a8d579ef5d26537394fccdab2081416 168 Pfam PF01724 Domain of unknown function DUF29 11 165 2.2E-36 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_03450 e1859fdf9b9a57ac340d15272080a331 161 SUPERFAMILY SSF55718 18 152 1.11E-25 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THERU_03450 e1859fdf9b9a57ac340d15272080a331 161 Pfam PF02036 SCP-2 sterol transfer family 28 143 1.5E-16 T 12-10-2018 IPR003033 SCP2 sterol-binding domain THERU_03450 e1859fdf9b9a57ac340d15272080a331 161 Gene3D G3DSA:3.30.1050.10 20 152 3.7E-15 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THERU_06815 96a5c2400fe8b60179e0a5bbd9b7ded6 328 Gene3D G3DSA:1.10.3720.10 109 324 8.4E-22 T 12-10-2018 IPR035906 MetI-like superfamily THERU_06815 96a5c2400fe8b60179e0a5bbd9b7ded6 328 SUPERFAMILY SSF161098 114 312 4.84E-25 T 12-10-2018 IPR035906 MetI-like superfamily THERU_06815 96a5c2400fe8b60179e0a5bbd9b7ded6 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 327 2.5E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THERU_04265 fbdf649dbdbf27e88bc111ad22434432 151 SUPERFAMILY SSF102405 2 127 3.66E-32 T 12-10-2018 THERU_04265 fbdf649dbdbf27e88bc111ad22434432 151 Pfam PF02481 DNA recombination-mediator protein A 2 65 4.4E-8 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THERU_04265 fbdf649dbdbf27e88bc111ad22434432 151 Gene3D G3DSA:3.40.50.450 1 150 1.5E-38 T 12-10-2018 THERU_04265 fbdf649dbdbf27e88bc111ad22434432 151 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 5 125 3.9E-49 T 12-10-2018 IPR005268 Conserved hypothetical protein CHP00725 THERU_08000 5744adb1c9d4984b7cdf115f143b59b5 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 196 1.8E-56 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 THERU_08000 5744adb1c9d4984b7cdf115f143b59b5 203 Gene3D G3DSA:3.90.950.10 1 201 3.4E-67 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THERU_08000 5744adb1c9d4984b7cdf115f143b59b5 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 198 46.491 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 THERU_08000 5744adb1c9d4984b7cdf115f143b59b5 203 Pfam PF01725 Ham1 family 3 194 2.1E-54 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 THERU_08000 5744adb1c9d4984b7cdf115f143b59b5 203 SUPERFAMILY SSF52972 1 197 1.13E-61 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THERU_04480 7d141e16bf41daade4e0ac55782af8c9 63 SUPERFAMILY SSF47598 5 44 5.45E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 234 5.4E-114 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 SUPERFAMILY SSF54211 1 181 1.21E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 42.743 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 Gene3D G3DSA:3.30.230.70 13 251 8.8E-66 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 SUPERFAMILY SSF55666 154 235 3.53E-22 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 Pfam PF03725 3' exoribonuclease family, domain 2 158 222 9.2E-12 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site THERU_03560 995e18a2e68fe12f225ad1419ae9643c 254 Pfam PF01138 3' exoribonuclease family, domain 1 10 142 1.0E-24 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THERU_02015 35b7857fe1f2b6caf9c1becaf7c348cf 141 TIGRFAM TIGR02805 exbB2: tonB-system energizer ExbB 2 136 9.7E-49 T 12-10-2018 IPR014172 TonB-system energizer ExbB type-2 GO:0016020|GO:0055085 THERU_02015 35b7857fe1f2b6caf9c1becaf7c348cf 141 Pfam PF01618 MotA/TolQ/ExbB proton channel family 45 136 2.4E-28 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THERU_05745 c8162654df266d249a6b260546540cb2 1647 Pfam PF05567 Neisseria PilC beta-propeller domain 1067 1464 2.1E-19 T 12-10-2018 IPR008707 PilC beta-propeller domain THERU_01645 e75cee4f9c0aaeb5312b8de2b0d06900 657 SUPERFAMILY SSF52540 243 650 4.96E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_01645 e75cee4f9c0aaeb5312b8de2b0d06900 657 Gene3D G3DSA:3.40.50.300 467 652 9.6E-21 T 12-10-2018 THERU_04380 f59bfe0ba7ebd5cc6249c5bdb5d75425 309 Pfam PF12469 CRISPR-associated protein 7 94 1.4E-12 T 12-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal THERU_04380 f59bfe0ba7ebd5cc6249c5bdb5d75425 309 Gene3D G3DSA:3.30.70.2220 1 259 8.1E-26 T 12-10-2018 IPR038242 Cmr2, N-terminal domain superfamily THERU_03730 44cf1b6f997d251c3d4ec578ced74f80 69 Pfam PF04023 FeoA domain 2 68 1.8E-14 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 THERU_03730 44cf1b6f997d251c3d4ec578ced74f80 69 SMART SM00899 1 69 3.9E-7 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 THERU_03730 44cf1b6f997d251c3d4ec578ced74f80 69 Gene3D G3DSA:2.30.30.90 9 69 5.1E-15 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain THERU_03730 44cf1b6f997d251c3d4ec578ced74f80 69 SUPERFAMILY SSF50037 2 69 1.03E-12 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal THERU_04780 e4bb6856ee0c19863b2a3947cb0dd924 260 Pfam PF03631 Virulence factor BrkB 20 248 1.1E-11 T 12-10-2018 IPR017039 Virulence factor BrkB THERU_00010 0ef8fbd391f4a8b5d1ad31076cb2f20c 119 Pfam PF02416 mttA/Hcf106 family 3 46 4.9E-6 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THERU_00770 e7dea78f7f2b4da735816dea008668da 352 Pfam PF01594 AI-2E family transporter 15 340 2.2E-56 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 8.7E-40 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 8.7E-40 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 8.7E-40 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 8.7E-40 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 8.7E-40 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 5 487 9.8E-166 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02465 ad5ef4e2f73e8c8330fc3740a46b6feb 491 Pfam PF00361 Proton-conducting membrane transporter 126 419 2.2E-76 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_07345 a161c423a692928275b4e7e76cf13ea1 98 Pfam PF00276 Ribosomal protein L23 6 93 6.4E-32 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THERU_07345 a161c423a692928275b4e7e76cf13ea1 98 Gene3D G3DSA:3.30.70.330 4 97 3.8E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily THERU_07345 a161c423a692928275b4e7e76cf13ea1 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 97 20.662 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THERU_07345 a161c423a692928275b4e7e76cf13ea1 98 SUPERFAMILY SSF54189 5 94 3.78E-29 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_05130 2b75547d8a9c8d76c362f8c5da67c733 139 Gene3D G3DSA:3.40.50.1010 1 95 1.8E-7 T 12-10-2018 THERU_05130 2b75547d8a9c8d76c362f8c5da67c733 139 SUPERFAMILY SSF88723 17 92 2.8E-8 T 12-10-2018 IPR029060 PIN-like domain superfamily THERU_05045 40896aa85dddcdb1e2a4b2263e173482 244 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 44 3.8E-11 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal THERU_05045 40896aa85dddcdb1e2a4b2263e173482 244 TIGRFAM TIGR02592 cas_Cas5h: CRISPR-associated protein Cas5, subtype I-B/HMARI 3 210 1.8E-45 T 12-10-2018 IPR013421 CRISPR-associated protein Cas5, HALMA THERU_05045 40896aa85dddcdb1e2a4b2263e173482 244 Gene3D G3DSA:3.30.70.2660 1 169 2.0E-8 T 12-10-2018 THERU_05045 40896aa85dddcdb1e2a4b2263e173482 244 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 167 4.0E-15 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 THERU_01245 7c398217b475a82b5873d65bc62cb5db 209 Gene3D G3DSA:3.30.1310.20 55 117 3.3E-64 T 12-10-2018 THERU_01245 7c398217b475a82b5873d65bc62cb5db 209 SUPERFAMILY SSF53271 1 208 3.15E-40 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_01245 7c398217b475a82b5873d65bc62cb5db 209 Gene3D G3DSA:3.40.50.2020 3 205 3.3E-64 T 12-10-2018 THERU_01245 7c398217b475a82b5873d65bc62cb5db 209 Pfam PF00156 Phosphoribosyl transferase domain 2 190 1.8E-26 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THERU_01715 41c94a4fba2635c3925a5e648ba7b6d5 295 Pfam PF00152 tRNA synthetases class II (D, K and N) 6 285 4.4E-26 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THERU_01715 41c94a4fba2635c3925a5e648ba7b6d5 295 SUPERFAMILY SSF55681 3 286 3.38E-49 T 12-10-2018 THERU_01715 41c94a4fba2635c3925a5e648ba7b6d5 295 Gene3D G3DSA:3.30.930.10 2 289 2.8E-64 T 12-10-2018 THERU_01475 4a97d500e47cca6b47736af3e03f9b14 123 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 5 123 27.265 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01475 4a97d500e47cca6b47736af3e03f9b14 123 Gene3D G3DSA:3.30.420.100 4 123 3.5E-40 T 12-10-2018 THERU_01475 4a97d500e47cca6b47736af3e03f9b14 123 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 123 2.1E-45 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THERU_01475 4a97d500e47cca6b47736af3e03f9b14 123 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 6 123 2.4E-37 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THERU_01475 4a97d500e47cca6b47736af3e03f9b14 123 SUPERFAMILY SSF53137 6 121 8.07E-47 T 12-10-2018 THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 Pfam PF13500 AAA domain 2 175 8.2E-40 T 12-10-2018 THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 168 1.3E-49 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 Gene3D G3DSA:3.40.50.300 2 202 3.8E-50 T 12-10-2018 THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 SUPERFAMILY SSF52540 1 210 5.43E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 PIRSF PIRSF006755 1 208 3.0E-55 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THERU_06455 be607ffe1ac5190750e9020beb1007f8 217 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 202 24.506 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THERU_02760 786b7da2f9559d6eeca6695015928092 137 Pfam PF09990 Predicted membrane protein (DUF2231) 44 135 1.4E-6 T 12-10-2018 IPR019251 Domain of unknown function DUF2231, transmembrane THERU_05150 dd0e84f9e6daa9bf89d65898eda3be95 116 SUPERFAMILY SSF110857 3 114 3.4E-32 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily THERU_05150 dd0e84f9e6daa9bf89d65898eda3be95 116 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 115 7.0E-26 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like THERU_05150 dd0e84f9e6daa9bf89d65898eda3be95 116 Gene3D G3DSA:3.10.490.10 2 116 7.5E-34 T 12-10-2018 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 178 199 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 2.9E-41 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 199 211 1.4E-6 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 105 124 1.4E-6 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 157 183 1.4E-6 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 SUPERFAMILY SSF56655 5 255 5.37E-70 T 12-10-2018 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 Gene3D G3DSA:3.40.190.80 142 256 4.3E-27 T 12-10-2018 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 Gene3D G3DSA:3.30.540.10 2 141 1.8E-40 T 12-10-2018 THERU_06240 45402edfc9bf24fdf8e2063f67c0548a 261 Pfam PF00459 Inositol monophosphatase family 5 233 3.8E-55 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THERU_04335 514309a15f66b23a01a0958494389b1e 201 SUPERFAMILY SSF51905 3 191 1.2E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_04335 514309a15f66b23a01a0958494389b1e 201 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 45 60 1.5E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_04335 514309a15f66b23a01a0958494389b1e 201 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.5E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_04335 514309a15f66b23a01a0958494389b1e 201 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 1.5E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_04335 514309a15f66b23a01a0958494389b1e 201 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 1.5E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THERU_04335 514309a15f66b23a01a0958494389b1e 201 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 161 1.2E-9 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THERU_04335 514309a15f66b23a01a0958494389b1e 201 Gene3D G3DSA:3.50.50.60 4 191 4.5E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01250 a28c4f277ec417079f449a888516e043 497 SUPERFAMILY SSF50998 63 421 2.39E-11 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THERU_07960 8b422864d7f105f222a6cb9f3865c80d 262 SUPERFAMILY SSF53756 2 240 7.85E-36 T 12-10-2018 THERU_07960 8b422864d7f105f222a6cb9f3865c80d 262 Gene3D G3DSA:3.40.50.2000 103 252 8.5E-21 T 12-10-2018 THERU_07960 8b422864d7f105f222a6cb9f3865c80d 262 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 112 240 2.9E-17 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 222 1.7E-71 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 Gene3D G3DSA:3.40.1280.10 1 172 2.4E-60 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 Gene3D G3DSA:1.10.1270.20 173 229 7.3E-24 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 216 3.9E-57 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 247 83.178 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 SUPERFAMILY SSF75217 1 223 3.93E-78 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases THERU_07430 8132e02b74cfb4b23d8264465b548a29 247 PIRSF PIRSF000386 1 246 5.8E-85 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 90 3.3E-35 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 Pfam PF01478 Type IV leader peptidase family 102 210 7.8E-20 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 167 177 2.7E-7 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 190 205 2.7E-7 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 110 127 2.7E-7 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THERU_03860 fd0cdaf3c0ee20c8aaca273d518317f9 249 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 178 189 2.7E-7 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THERU_03170 f2a2a10edb868e9a3d92bc9f2a1233f5 409 Pfam PF02687 FtsX-like permease family 303 401 1.0E-13 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THERU_03170 f2a2a10edb868e9a3d92bc9f2a1233f5 409 Pfam PF12704 MacB-like periplasmic core domain 19 244 2.4E-20 T 12-10-2018 IPR025857 MacB-like periplasmic core domain THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 Gene3D G3DSA:3.60.120.10 1 475 1.7E-184 T 12-10-2018 IPR005801 ADC synthase GO:0009058 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 PRINTS PR00095 Anthranilate synthase component I signature 420 434 1.3E-25 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 PRINTS PR00095 Anthranilate synthase component I signature 325 338 1.3E-25 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 PRINTS PR00095 Anthranilate synthase component I signature 405 419 1.3E-25 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 PRINTS PR00095 Anthranilate synthase component I signature 311 324 1.3E-25 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 28 471 5.2E-168 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 SUPERFAMILY SSF56322 18 473 2.88E-162 T 12-10-2018 IPR005801 ADC synthase GO:0009058 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 154 1.8E-23 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THERU_01290 2ffdbc51ab02d2a3a68454283154ad71 476 Pfam PF00425 chorismate binding enzyme 210 463 1.1E-103 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 Pfam PF13624 SurA N-terminal domain 1 156 8.5E-32 T 12-10-2018 THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 Gene3D G3DSA:1.10.4030.30 196 332 3.9E-7 T 12-10-2018 THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 Gene3D G3DSA:3.10.50.40 215 297 3.9E-7 T 12-10-2018 THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 Pfam PF13145 PPIC-type PPIASE domain 197 306 3.6E-8 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 SUPERFAMILY SSF109998 42 241 4.97E-24 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily THERU_02240 3b72c26eff29e92b68a1acc649b397c9 441 Gene3D G3DSA:1.10.4030.30 39 182 1.8E-15 T 12-10-2018 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 SUPERFAMILY SSF63411 230 415 2.39E-32 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 Pfam PF05193 Peptidase M16 inactive domain 173 347 9.7E-39 T 12-10-2018 IPR007863 Peptidase M16, C-terminal THERU_01760 497044dab26f071d8e3c6f74735e2614 417 Gene3D G3DSA:3.30.830.10 6 224 1.5E-72 T 12-10-2018 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 SUPERFAMILY SSF63411 8 213 2.83E-62 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 Gene3D G3DSA:3.30.830.10 226 417 2.9E-40 T 12-10-2018 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 41 64 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 THERU_01760 497044dab26f071d8e3c6f74735e2614 417 Pfam PF00675 Insulinase (Peptidase family M16) 24 164 2.9E-31 T 12-10-2018 IPR011765 Peptidase M16, N-terminal THERU_07550 84902369766d97db2628fd8bd9f2c2b4 435 Gene3D G3DSA:3.60.110.10 190 435 3.1E-20 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_07550 84902369766d97db2628fd8bd9f2c2b4 435 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 57 418 1.2E-67 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THERU_07550 84902369766d97db2628fd8bd9f2c2b4 435 SUPERFAMILY SSF56317 192 431 1.19E-38 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THERU_07550 84902369766d97db2628fd8bd9f2c2b4 435 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 435 15.607 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THERU_07550 84902369766d97db2628fd8bd9f2c2b4 435 Pfam PF00795 Carbon-nitrogen hydrolase 198 431 1.4E-18 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THERU_06080 273b7e72bcbd6ee2f358083f2e2215eb 523 Gene3D G3DSA:3.60.21.70 128 521 4.1E-100 T 12-10-2018 IPR038607 PhoD-like superfamily THERU_06080 273b7e72bcbd6ee2f358083f2e2215eb 523 Gene3D G3DSA:2.60.40.380 24 127 4.6E-28 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 THERU_06080 273b7e72bcbd6ee2f358083f2e2215eb 523 SUPERFAMILY SSF56300 128 495 2.34E-23 T 12-10-2018 THERU_06080 273b7e72bcbd6ee2f358083f2e2215eb 523 Pfam PF09423 PhoD-like phosphatase 136 490 1.6E-75 T 12-10-2018 IPR018946 Alkaline phosphatase D-related THERU_06080 273b7e72bcbd6ee2f358083f2e2215eb 523 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 33 125 2.1E-24 T 12-10-2018 IPR032093 Phospholipase D, N-terminal THERU_04765 62a94ef45e6f1c8bfb1442837e730dbf 144 Pfam PF00011 Hsp20/alpha crystallin family 44 144 7.9E-24 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain THERU_04765 62a94ef45e6f1c8bfb1442837e730dbf 144 Gene3D G3DSA:2.60.40.790 3 144 7.5E-44 T 12-10-2018 IPR008978 HSP20-like chaperone THERU_04765 62a94ef45e6f1c8bfb1442837e730dbf 144 SUPERFAMILY SSF49764 12 143 6.75E-41 T 12-10-2018 IPR008978 HSP20-like chaperone THERU_02230 8fdb3de9ff91b3b69a8d09fdb6c4197e 403 Pfam PF00155 Aminotransferase class I and II 33 389 3.4E-53 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THERU_02230 8fdb3de9ff91b3b69a8d09fdb6c4197e 403 Gene3D G3DSA:3.90.1150.10 296 392 1.2E-115 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THERU_02230 8fdb3de9ff91b3b69a8d09fdb6c4197e 403 Gene3D G3DSA:3.40.640.10 66 295 1.2E-115 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THERU_02230 8fdb3de9ff91b3b69a8d09fdb6c4197e 403 SUPERFAMILY SSF53383 4 397 1.2E-107 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THERU_02230 8fdb3de9ff91b3b69a8d09fdb6c4197e 403 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THERU_02185 59bae73bd7b08714bf54494fd0406967 138 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 9 137 5.0E-45 T 12-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 THERU_02185 59bae73bd7b08714bf54494fd0406967 138 Gene3D G3DSA:3.55.10.10 1 138 2.1E-30 T 12-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 THERU_02185 59bae73bd7b08714bf54494fd0406967 138 SUPERFAMILY SSF69819 4 138 9.02E-29 T 12-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 THERU_02185 59bae73bd7b08714bf54494fd0406967 138 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 138 2.2E-30 T 12-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 THERU_02605 48e7066c1b5205d1568335bf5aae0943 173 Pfam PF01597 Glycine cleavage H-protein 39 159 1.2E-29 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THERU_02605 48e7066c1b5205d1568335bf5aae0943 173 SUPERFAMILY SSF51230 48 159 1.86E-20 T 12-10-2018 IPR011053 Single hybrid motif THERU_02605 48e7066c1b5205d1568335bf5aae0943 173 Gene3D G3DSA:2.40.50.100 31 160 3.6E-20 T 12-10-2018 THERU_04285 ee67912e00c32bb74d3b961b7637dcef 388 SUPERFAMILY SSF103473 7 387 4.19E-59 T 12-10-2018 IPR036259 MFS transporter superfamily THERU_04285 ee67912e00c32bb74d3b961b7637dcef 388 Gene3D G3DSA:1.20.1250.20 3 383 3.5E-77 T 12-10-2018 THERU_04285 ee67912e00c32bb74d3b961b7637dcef 388 Pfam PF07690 Major Facilitator Superfamily 17 351 1.7E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THERU_01020 979aa611b63572d915d0df8e7dcfb1e5 320 Gene3D G3DSA:3.20.20.140 4 184 1.9E-9 T 12-10-2018 THERU_01020 979aa611b63572d915d0df8e7dcfb1e5 320 SUPERFAMILY SSF89550 7 171 4.32E-13 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THERU_04980 925b56fc5a01725d2cd21028c29bb78c 254 Pfam PF01925 Sulfite exporter TauE/SafE 5 248 3.4E-37 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THERU_05900 ad607b58323fb6ad8bc598854f372597 281 Gene3D G3DSA:3.90.226.10 64 240 7.7E-23 T 12-10-2018 THERU_05900 ad607b58323fb6ad8bc598854f372597 281 SUPERFAMILY SSF52096 12 240 1.06E-27 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THERU_05900 ad607b58323fb6ad8bc598854f372597 281 Pfam PF01972 Serine dehydrogenase proteinase 2 278 2.7E-136 T 12-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 THERU_00705 960fb344d58960e36998a0ecac71a323 277 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 265 2.5E-57 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THERU_00755 400fbc1b2fc299085b59052c754095f8 330 SUPERFAMILY SSF101478 2 317 3.66E-51 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THERU_00755 400fbc1b2fc299085b59052c754095f8 330 Gene3D G3DSA:1.10.4080.10 1 328 3.3E-52 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THERU_00755 400fbc1b2fc299085b59052c754095f8 330 Pfam PF03747 ADP-ribosylglycohydrolase 8 293 5.0E-49 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 THERU_06765 8867bb04255b7670f554a2712460744e 168 Gene3D G3DSA:1.20.1220.20 5 165 5.1E-24 T 12-10-2018 THERU_06765 8867bb04255b7670f554a2712460744e 168 Pfam PF01724 Domain of unknown function DUF29 11 162 6.4E-40 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_08430 d108fcfba07e9d86e2d2adecd03550cd 132 Pfam PF05433 Glycine zipper 2TM domain 30 69 4.2E-10 T 12-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 THERU_01940 ecc779ee94150317a41ddadc039e08d0 311 Pfam PF04463 Protein of unknown function (DUF523) 8 148 1.5E-32 T 12-10-2018 IPR007553 Domain of unknown function DUF523 THERU_01940 ecc779ee94150317a41ddadc039e08d0 311 PIRSF PIRSF037004 1 311 4.3E-104 T 12-10-2018 IPR017087 Uncharacterised conserved protein UCP037004 THERU_01940 ecc779ee94150317a41ddadc039e08d0 311 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 3.6E-35 T 12-10-2018 IPR013560 Domain of unknown function DUF1722 THERU_00210 26650a48596219d9ceb618f215bfba67 148 SUPERFAMILY SSF51230 23 133 1.3E-29 T 12-10-2018 IPR011053 Single hybrid motif THERU_00210 26650a48596219d9ceb618f215bfba67 148 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 141 33.123 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THERU_00210 26650a48596219d9ceb618f215bfba67 148 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 59 88 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THERU_00210 26650a48596219d9ceb618f215bfba67 148 Gene3D G3DSA:2.40.50.100 7 138 2.4E-33 T 12-10-2018 THERU_00210 26650a48596219d9ceb618f215bfba67 148 Pfam PF01597 Glycine cleavage H-protein 24 136 4.7E-40 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THERU_01055 9f764c4aab855ffea79c8d18d6a10c59 141 SUPERFAMILY SSF111126 20 125 3.4E-6 T 12-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 448 460 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 Gene3D G3DSA:3.40.50.2000 9 119 3.5E-8 T 12-10-2018 THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 Pfam PF00343 Carbohydrate phosphorylase 228 470 5.2E-26 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 2 555 7.0E-158 T 12-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 SUPERFAMILY SSF53756 2 555 1.2E-143 T 12-10-2018 THERU_01000 7a394d58bc43e3bb42f3e8efc059d714 559 Gene3D G3DSA:3.40.50.2000 279 513 1.8E-43 T 12-10-2018 THERU_00825 44783a0f5990f8e1567006f316ee5a20 249 Gene3D G3DSA:3.40.30.10 33 197 8.1E-31 T 12-10-2018 THERU_00825 44783a0f5990f8e1567006f316ee5a20 249 SUPERFAMILY SSF52833 34 181 1.36E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_06275 dd149e3c4a8d55270061dd1a91d1c571 117 SMART SM00960 4 93 1.9E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain THERU_06275 dd149e3c4a8d55270061dd1a91d1c571 117 Pfam PF03259 Roadblock/LC7 domain 6 93 1.2E-18 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain THERU_06275 dd149e3c4a8d55270061dd1a91d1c571 117 Gene3D G3DSA:3.30.450.30 1 117 1.6E-32 T 12-10-2018 THERU_06275 dd149e3c4a8d55270061dd1a91d1c571 117 SUPERFAMILY SSF103196 2 117 2.44E-29 T 12-10-2018 THERU_05385 7f2a5328f727aa058b93d89a7ba29969 521 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 268 341 2.2E-16 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_05340 a760e2a1f93c6ce17220ab05443fcc1f 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_05340 a760e2a1f93c6ce17220ab05443fcc1f 91 Pfam PF00708 Acylphosphatase 5 89 3.2E-25 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_05340 a760e2a1f93c6ce17220ab05443fcc1f 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_05340 a760e2a1f93c6ce17220ab05443fcc1f 91 SUPERFAMILY SSF54975 3 90 9.16E-28 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THERU_05340 a760e2a1f93c6ce17220ab05443fcc1f 91 Gene3D G3DSA:3.30.70.100 1 90 1.4E-29 T 12-10-2018 THERU_06625 356a671fbacf42be006a43b7c72f1d23 39 Gene3D G3DSA:3.90.180.10 1 39 1.1E-5 T 12-10-2018 THERU_06625 356a671fbacf42be006a43b7c72f1d23 39 Pfam PF13602 Zinc-binding dehydrogenase 5 39 2.5E-6 T 12-10-2018 THERU_06425 f0ee9c5d7c81d148832b1a53b462601d 197 Pfam PF05275 Copper resistance protein B precursor (CopB) 1 197 3.6E-61 T 12-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 THERU_06225 874cdd9f9b91bb093f80fd600643795c 283 Pfam PF03739 Predicted permease YjgP/YjgQ family 10 217 1.6E-11 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THERU_06095 b103443491bcaf858b03e020203027e7 149 Pfam PF01618 MotA/TolQ/ExbB proton channel family 48 131 8.4E-20 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THERU_02170 0b880b3dd9c3e10a3ec324414e4142b6 85 Pfam PF00216 Bacterial DNA-binding protein 1 65 5.7E-12 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_02170 0b880b3dd9c3e10a3ec324414e4142b6 85 SMART SM00411 1 75 4.3E-5 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THERU_02170 0b880b3dd9c3e10a3ec324414e4142b6 85 Gene3D G3DSA:4.10.520.10 1 72 3.6E-12 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_02170 0b880b3dd9c3e10a3ec324414e4142b6 85 SUPERFAMILY SSF47729 1 75 6.77E-15 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THERU_06020 d81df8c9cf71c752945e6ff1f942583d 175 SUPERFAMILY SSF100950 1 172 1.73E-42 T 12-10-2018 IPR037171 NagB/RpiA transferase-like THERU_06020 d81df8c9cf71c752945e6ff1f942583d 175 Gene3D G3DSA:3.40.50.1360 1 174 3.2E-49 T 12-10-2018 THERU_06020 d81df8c9cf71c752945e6ff1f942583d 175 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 1 169 3.5E-42 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 THERU_06020 d81df8c9cf71c752945e6ff1f942583d 175 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 1 171 7.7E-41 T 12-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 THERU_02280 e99f940a652008d219f7b4cd1da8f474 194 SUPERFAMILY SSF52499 10 193 1.7E-54 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THERU_02280 e99f940a652008d219f7b4cd1da8f474 194 Gene3D G3DSA:3.40.50.850 7 194 4.1E-62 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THERU_02280 e99f940a652008d219f7b4cd1da8f474 194 Pfam PF00857 Isochorismatase family 10 192 3.6E-38 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 THERU_03905 e460b51c2fc51f15c3e8c47eda73f86a 96 SUPERFAMILY SSF57997 6 60 2.09E-5 T 12-10-2018 THERU_03905 e460b51c2fc51f15c3e8c47eda73f86a 96 Gene3D G3DSA:1.20.5.340 4 75 1.3E-8 T 12-10-2018 THERU_01965 9528c27a5a116433fe3f0bc7b18a6754 114 Pfam PF02036 SCP-2 sterol transfer family 21 103 8.5E-5 T 12-10-2018 IPR003033 SCP2 sterol-binding domain THERU_08100 424874c4c2f7046071f5d65371d26c55 268 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 263 14.828 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THERU_08100 424874c4c2f7046071f5d65371d26c55 268 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 257 6.0E-54 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THERU_08100 424874c4c2f7046071f5d65371d26c55 268 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 260 3.6E-37 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THERU_05355 466fd8fb1ab758aff0f891285289e395 182 Pfam PF04205 FMN-binding domain 100 171 3.1E-4 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THERU_07135 d796139d24272346e292fa4f52455b2b 278 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 6 277 2.0E-114 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THERU_07135 d796139d24272346e292fa4f52455b2b 278 Pfam PF05681 Fumarate hydratase (Fumerase) 8 276 7.1E-114 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THERU_00660 4080ea0909759daf29b05483cd185afd 294 Pfam PF01882 Protein of unknown function DUF58 187 260 2.8E-13 T 12-10-2018 IPR002881 Domain of unknown function DUF58 THERU_02820 423832742442f9fce1c8b41f34261e58 263 Pfam PF06230 Protein of unknown function (DUF1009) 50 258 3.5E-65 T 12-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 THERU_02820 423832742442f9fce1c8b41f34261e58 263 Gene3D G3DSA:3.40.50.20 1 122 1.0E-19 T 12-10-2018 THERU_02820 423832742442f9fce1c8b41f34261e58 263 Gene3D G3DSA:3.40.140.80 124 262 2.8E-42 T 12-10-2018 THERU_08490 08e0edc91809fd612aff16c8de7feb66 76 Gene3D G3DSA:3.30.110.40 1 74 7.9E-25 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_08490 08e0edc91809fd612aff16c8de7feb66 76 Pfam PF01206 Sulfurtransferase TusA 5 74 7.0E-21 T 12-10-2018 IPR001455 TusA-like domain THERU_08490 08e0edc91809fd612aff16c8de7feb66 76 SUPERFAMILY SSF64307 3 74 1.16E-20 T 12-10-2018 IPR036868 TusA-like domain superfamily THERU_08490 08e0edc91809fd612aff16c8de7feb66 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 12-10-2018 IPR001455 TusA-like domain THERU_08255 d85d15447931117c6c8d14f8215a439e 348 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 4 343 3.3E-119 T 12-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 199 217 4.5E-32 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 263 278 4.5E-32 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 294 315 4.5E-32 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 7 29 4.5E-32 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 219 236 4.5E-32 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 SUPERFAMILY SSF160544 235 342 8.24E-36 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal THERU_08255 d85d15447931117c6c8d14f8215a439e 348 Pfam PF01312 FlhB HrpN YscU SpaS Family 4 339 5.3E-120 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THERU_08255 d85d15447931117c6c8d14f8215a439e 348 Gene3D G3DSA:3.40.1690.10 209 347 8.0E-52 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal THERU_07625 dbd7e30e7cda1d9af45847cf8673d44e 75 Pfam PF04325 Protein of unknown function (DUF465) 17 63 3.4E-10 T 12-10-2018 IPR007420 Protein of unknown function DUF465 THERU_07625 dbd7e30e7cda1d9af45847cf8673d44e 75 Gene3D G3DSA:1.20.58.660 2 75 6.8E-10 T 12-10-2018 THERU_05015 d1c649299e0a52bce7a922ed7a9418ec 36 Pfam PF13610 DDE domain 1 35 6.3E-7 T 12-10-2018 IPR032874 DDE domain THERU_07015 9d0ff69e6dba0c7fe22c0acf11c8ccd5 370 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 18 241 4.6E-51 T 12-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 THERU_05470 4eb1bbf377be0500c15f12d2e970fe58 195 SUPERFAMILY SSF110997 129 186 1.23E-9 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THERU_05470 4eb1bbf377be0500c15f12d2e970fe58 195 Pfam PF05036 Sporulation related domain 128 193 2.8E-11 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 THERU_05470 4eb1bbf377be0500c15f12d2e970fe58 195 Gene3D G3DSA:3.30.70.1070 129 193 2.5E-10 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THERU_02970 e7f648e1600fc85bc71bafa53b0a191c 230 Pfam PF02591 C4-type zinc ribbon domain 198 229 2.9E-9 T 12-10-2018 IPR003743 C4-type zinc ribbon domain THERU_04410 63a5ef28fe24811b7c86463a817f1e9e 350 Pfam PF03787 RAMP superfamily 119 344 9.8E-15 T 12-10-2018 IPR005537 CRISPR type III-associated RAMP protein THERU_04410 63a5ef28fe24811b7c86463a817f1e9e 350 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 118 343 2.1E-50 T 12-10-2018 IPR010172 CRISPR-associated protein, TM1791 THERU_05160 e963ec6396a51023d0d2294de8a9c7e3 522 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 356 428 1.6E-5 T 12-10-2018 IPR018693 Protein of unknown function DUF2192 THERU_05160 e963ec6396a51023d0d2294de8a9c7e3 522 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 270 343 5.3E-16 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal THERU_00925 d8ce6c9cd72ca2923e213389a568d9a7 164 SUPERFAMILY SSF103196 14 136 1.92E-15 T 12-10-2018 THERU_00925 d8ce6c9cd72ca2923e213389a568d9a7 164 Gene3D G3DSA:3.30.450.30 9 139 6.4E-25 T 12-10-2018 THERU_04005 1c34bfe78c04b524d0290e4db93ae762 426 PRINTS PR01806 Virulence factor MviN signature 39 58 5.5E-5 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_04005 1c34bfe78c04b524d0290e4db93ae762 426 PRINTS PR01806 Virulence factor MviN signature 133 157 5.5E-5 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_04005 1c34bfe78c04b524d0290e4db93ae762 426 PRINTS PR01806 Virulence factor MviN signature 392 411 5.5E-5 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_04005 1c34bfe78c04b524d0290e4db93ae762 426 Pfam PF03023 MviN-like protein 34 423 1.4E-24 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THERU_06045 87b1af9093e764ccd693b7fa07403a55 129 Gene3D G3DSA:2.170.120.30 35 123 5.8E-10 T 12-10-2018 THERU_05555 4b0e1bf7526992e085c27d5ef090a46e 263 Gene3D G3DSA:3.20.20.410 1 244 6.6E-72 T 12-10-2018 IPR036520 UPF0759 superfamily THERU_05555 4b0e1bf7526992e085c27d5ef090a46e 263 Pfam PF01904 Protein of unknown function DUF72 20 240 2.9E-51 T 12-10-2018 IPR002763 Protein of unknown function DUF72 THERU_05555 4b0e1bf7526992e085c27d5ef090a46e 263 SUPERFAMILY SSF117396 2 242 5.89E-66 T 12-10-2018 IPR036520 UPF0759 superfamily THERU_02610 5fd050fefccdcc08a90c9692037d3362 256 SUPERFAMILY SSF144020 12 255 3.14E-57 T 12-10-2018 IPR024064 FdhE-like superfamily THERU_02610 5fd050fefccdcc08a90c9692037d3362 256 Pfam PF04216 Protein involved in formate dehydrogenase formation 51 254 1.6E-35 T 12-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THERU_02610 5fd050fefccdcc08a90c9692037d3362 256 Gene3D G3DSA:3.90.1670.10 8 256 2.4E-46 T 12-10-2018 IPR024064 FdhE-like superfamily THERU_06595 52d39777f09ecf47a540432562d9381c 297 SUPERFAMILY SSF51730 8 286 3.53E-103 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like THERU_06595 52d39777f09ecf47a540432562d9381c 297 Pfam PF02219 Methylenetetrahydrofolate reductase 8 284 1.1E-110 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 THERU_06595 52d39777f09ecf47a540432562d9381c 297 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 13 285 5.5E-114 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 THERU_06595 52d39777f09ecf47a540432562d9381c 297 Gene3D G3DSA:3.20.20.220 2 291 1.4E-115 T 12-10-2018 THERU_05275 a926daa4205d686cca24b45a9e074dab 336 Pfam PF13087 AAA domain 1 170 9.3E-16 T 12-10-2018 THERU_05275 a926daa4205d686cca24b45a9e074dab 336 Gene3D G3DSA:3.40.960.10 195 333 8.5E-6 T 12-10-2018 THERU_05275 a926daa4205d686cca24b45a9e074dab 336 Gene3D G3DSA:3.40.50.300 6 194 4.3E-24 T 12-10-2018 THERU_05275 a926daa4205d686cca24b45a9e074dab 336 SUPERFAMILY SSF52540 1 170 4.93E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_05275 a926daa4205d686cca24b45a9e074dab 336 Pfam PF08373 RAP domain 265 312 3.6E-6 T 12-10-2018 IPR013584 RAP domain THERU_04390 f74c6b017aae20efcc2ad0652c1ea7cc 326 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 6 322 6.0E-32 T 12-10-2018 IPR010165 CRISPR-associated protein, TM1793 THERU_04390 f74c6b017aae20efcc2ad0652c1ea7cc 326 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 46 286 7.1E-17 T 12-10-2018 IPR019117 CRISPR-associated protein, Cmr3 THERU_04375 effa62eebeae4d1be1439bbc22d26ec8 358 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 8 154 6.4E-17 T 12-10-2018 IPR007522 CRISPR-associated protein TM1795 THERU_04375 effa62eebeae4d1be1439bbc22d26ec8 358 Pfam PF03787 RAMP superfamily 7 152 6.4E-8 T 12-10-2018 IPR005537 CRISPR type III-associated RAMP protein THERU_01305 9b273869358dc59b1fb697cb9c9c74b8 103 Pfam PF08734 GYD domain 4 94 1.9E-24 T 12-10-2018 IPR014845 Protein GYD/TTHA1554 THERU_05890 013ee382e15dd7074f3589976bf374f3 214 Pfam PF04028 Domain of unknown function (DUF374) 60 128 4.1E-24 T 12-10-2018 IPR007172 Domain of unknown function DUF374 THERU_05890 013ee382e15dd7074f3589976bf374f3 214 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 25 128 4.0E-40 T 12-10-2018 IPR007172 Domain of unknown function DUF374 THERU_05270 929c5b199f05c29442fd065aeba7132c 622 Pfam PF13086 AAA domain 187 570 8.6E-12 T 12-10-2018 THERU_05270 929c5b199f05c29442fd065aeba7132c 622 SUPERFAMILY SSF52540 186 581 4.13E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_06340 52631631e7bcaf8c27c259d74a5a77ac 236 Pfam PF02698 DUF218 domain 74 230 3.6E-31 T 12-10-2018 IPR003848 Domain of unknown function DUF218 THERU_06340 52631631e7bcaf8c27c259d74a5a77ac 236 Gene3D G3DSA:3.40.50.620 92 198 4.4E-9 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THERU_08185 0bf79e4a7c67f0c4b1fd61127e3af1c8 71 Gene3D G3DSA:1.20.1220.20 16 71 1.5E-6 T 12-10-2018 THERU_08185 0bf79e4a7c67f0c4b1fd61127e3af1c8 71 Pfam PF01724 Domain of unknown function DUF29 22 70 3.0E-11 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_00840 2cd14fc7b2e896b5499cbcd4e53aca82 206 Pfam PF01148 Cytidylyltransferase family 40 203 1.6E-31 T 12-10-2018 THERU_00840 2cd14fc7b2e896b5499cbcd4e53aca82 206 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 168 194 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 THERU_00530 ac239c59e9ef19129246e24b9c5de48d 251 Pfam PF01578 Cytochrome C assembly protein 34 248 3.1E-22 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THERU_04570 b48d026a4a645a720f26ce9f4eff76dc 204 SUPERFAMILY SSF48452 72 188 1.79E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_04570 b48d026a4a645a720f26ce9f4eff76dc 204 Gene3D G3DSA:1.25.40.10 58 198 9.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_00480 73b7c9a0abf555553a3a0b0a54b2314b 407 SUPERFAMILY SSF56954 2 406 2.49E-72 T 12-10-2018 THERU_00480 73b7c9a0abf555553a3a0b0a54b2314b 407 Pfam PF02321 Outer membrane efflux protein 221 406 5.7E-28 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_00480 73b7c9a0abf555553a3a0b0a54b2314b 407 Pfam PF02321 Outer membrane efflux protein 16 199 4.5E-29 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THERU_00480 73b7c9a0abf555553a3a0b0a54b2314b 407 Gene3D G3DSA:1.20.1600.10 10 407 3.9E-73 T 12-10-2018 THERU_01260 a1f89bf9cd6397dfa0ba5d66038911ce 379 Gene3D G3DSA:3.30.420.40 117 217 3.5E-7 T 12-10-2018 THERU_01260 a1f89bf9cd6397dfa0ba5d66038911ce 379 SUPERFAMILY SSF53067 116 230 2.5E-7 T 12-10-2018 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 57 98 1.1E-8 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 Pfam PF00361 Proton-conducting membrane transporter 111 334 1.1E-49 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 200 221 2.9E-22 T 12-10-2018 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 289 301 2.9E-22 T 12-10-2018 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 222 248 2.9E-22 T 12-10-2018 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 88 108 2.9E-22 T 12-10-2018 THERU_06540 32b5c86f9090e64f661d2c072e605a15 760 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 60 85 2.9E-22 T 12-10-2018 THERU_02595 de9333f34050330dfbceae553bf14412 351 SUPERFAMILY SSF54001 112 264 1.21E-25 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THERU_02595 de9333f34050330dfbceae553bf14412 351 Pfam PF01841 Transglutaminase-like superfamily 147 263 3.3E-24 T 12-10-2018 IPR002931 Transglutaminase-like THERU_02595 de9333f34050330dfbceae553bf14412 351 SMART SM00460 191 265 3.0E-17 T 12-10-2018 IPR002931 Transglutaminase-like THERU_02595 de9333f34050330dfbceae553bf14412 351 Gene3D G3DSA:3.10.620.30 99 273 1.4E-22 T 12-10-2018 THERU_08375 50d99dbcdc3fee5224446b53dec8f16b 194 Pfam PF02630 SCO1/SenC 8 173 1.1E-43 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_08375 50d99dbcdc3fee5224446b53dec8f16b 194 Gene3D G3DSA:3.40.30.10 28 193 1.8E-57 T 12-10-2018 THERU_08375 50d99dbcdc3fee5224446b53dec8f16b 194 SUPERFAMILY SSF52833 30 193 9.75E-53 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02480 d61380064c080e8c2c6e5701aaa77685 177 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 164 1.8E-24 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02480 d61380064c080e8c2c6e5701aaa77685 177 Gene3D G3DSA:1.20.120.1200 4 166 1.7E-28 T 12-10-2018 THERU_07125 20d3265110c6ce474d03d1f9c5bc6370 255 SUPERFAMILY SSF53448 2 211 2.02E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_07125 20d3265110c6ce474d03d1f9c5bc6370 255 Gene3D G3DSA:3.90.550.10 2 144 2.3E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_07125 20d3265110c6ce474d03d1f9c5bc6370 255 Pfam PF00535 Glycosyl transferase family 2 4 120 7.3E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THERU_02005 34502a83507664c1cce86cb0fd91ca47 470 Pfam PF12801 4Fe-4S binding domain 146 183 5.7E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_02005 34502a83507664c1cce86cb0fd91ca47 470 Pfam PF12801 4Fe-4S binding domain 64 106 3.7E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THERU_02005 34502a83507664c1cce86cb0fd91ca47 470 SUPERFAMILY SSF54862 138 243 1.16E-9 T 12-10-2018 THERU_08115 d22a55c24b406d1a35d25adbe4dee1c2 264 Pfam PF03783 Curli production assembly/transport component CsgG 45 243 2.2E-21 T 12-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 THERU_08250 4d064438b7ef8c321156d95aed1f669e 75 Pfam PF11146 Protein of unknown function (DUF2905) 5 69 2.1E-26 T 12-10-2018 IPR021320 Protein of unknown function DUF2905 THERU_02735 b1056a45b39d12b057ce832496d243ad 370 SUPERFAMILY SSF51412 12 289 6.87E-43 T 12-10-2018 THERU_02735 b1056a45b39d12b057ce832496d243ad 370 Pfam PF03060 Nitronate monooxygenase 13 361 5.8E-62 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 THERU_02735 b1056a45b39d12b057ce832496d243ad 370 Gene3D G3DSA:3.20.20.70 9 366 2.9E-61 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THERU_02365 0c851f7e0b33f7b663414937d596f44b 319 Pfam PF03773 Predicted permease 26 314 1.6E-78 T 12-10-2018 IPR005524 Predicted permease DUF318 THERU_03005 9779e17a57ee79e074f6c47959964bb3 231 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 20 164 8.9E-12 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THERU_05755 b0ec0a84eaf84d6bfa72a783d510a009 218 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 5.1E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site THERU_01945 c6d49f08b41f6ce115635d28b5a9dc87 488 Gene3D G3DSA:3.50.50.60 3 108 1.7E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01945 c6d49f08b41f6ce115635d28b5a9dc87 488 SUPERFAMILY SSF51905 2 470 1.94E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THERU_01945 c6d49f08b41f6ce115635d28b5a9dc87 488 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 67 4.2E-11 T 12-10-2018 THERU_06640 69f88d5f57cea339d9c02f46c4c5e326 337 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 314 1.2E-70 T 12-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 THERU_03490 b6512c44b5677af207d9d83c1fd38a42 248 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 219 3.5E-21 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 SUPERFAMILY SSF116734 272 435 2.78E-19 T 12-10-2018 THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 Gene3D G3DSA:3.90.220.20 35 213 4.0E-21 T 12-10-2018 THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 Gene3D G3DSA:3.90.220.20 259 438 2.0E-29 T 12-10-2018 THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 Pfam PF01420 Type I restriction modification DNA specificity domain 78 199 1.3E-5 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 Pfam PF01420 Type I restriction modification DNA specificity domain 314 421 3.4E-5 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THERU_01915 8b01616bce58a772ddbc0ec0ee62b674 456 SUPERFAMILY SSF116734 26 206 1.64E-18 T 12-10-2018 THERU_04825 0179cb6aff900559fef4418bbdc9aa62 214 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 5.0E-50 T 12-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 THERU_04825 0179cb6aff900559fef4418bbdc9aa62 214 Gene3D G3DSA:1.10.1760.20 1 212 9.1E-58 T 12-10-2018 THERU_06770 b788318d57f966afff6d991c83683425 73 Gene3D G3DSA:3.40.50.2020 29 63 1.9E-6 T 12-10-2018 THERU_02795 f683948d3f599177c6d80aab5819f0ee 294 Gene3D G3DSA:3.40.50.300 38 290 7.6E-35 T 12-10-2018 THERU_02795 f683948d3f599177c6d80aab5819f0ee 294 Pfam PF06745 KaiC 38 290 1.1E-62 T 12-10-2018 IPR014774 KaiC-like domain THERU_02795 f683948d3f599177c6d80aab5819f0ee 294 SUPERFAMILY SSF52540 37 288 2.1E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THERU_02795 f683948d3f599177c6d80aab5819f0ee 294 TIGRFAM TIGR03878 thermo_KaiC_2: KaiC domain protein, AF_0795 family 35 292 1.2E-136 T 12-10-2018 IPR022373 KaiC domain-containing protein THERU_07080 d3c78bd2c8720f2175689cc056b8a25f 181 Gene3D G3DSA:3.40.50.2020 2 181 9.2E-55 T 12-10-2018 THERU_07080 d3c78bd2c8720f2175689cc056b8a25f 181 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 15 180 4.2E-46 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07080 d3c78bd2c8720f2175689cc056b8a25f 181 SUPERFAMILY SSF53271 3 180 1.05E-38 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like THERU_07080 d3c78bd2c8720f2175689cc056b8a25f 181 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 181 27.329 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THERU_07080 d3c78bd2c8720f2175689cc056b8a25f 181 Pfam PF00156 Phosphoribosyl transferase domain 48 162 4.1E-9 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THERU_07415 58377e92e7345f626f19923e867c721b 145 SUPERFAMILY SSF54909 25 123 3.98E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel THERU_07415 58377e92e7345f626f19923e867c721b 145 Gene3D G3DSA:3.30.70.100 59 141 2.6E-5 T 12-10-2018 THERU_06605 bd0eaba27219e9c1c80539f5d5c15b0a 97 Pfam PF08734 GYD domain 4 91 6.6E-30 T 12-10-2018 IPR014845 Protein GYD/TTHA1554 THERU_02800 3f817582229ba0c7ad33863f34d975ee 221 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 30 129 3.7E-37 T 12-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative THERU_04540 f4869cefe42a9d5513d6d8e5ca9bdca8 192 Pfam PF01548 Transposase 33 146 1.4E-11 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THERU_06270 d70b62f8ad026e6b901e051a7ba759a2 231 Pfam PF14332 Domain of unknown function (DUF4388) 4 127 3.8E-13 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 THERU_00095 5f77f99ed1a92ce0721d86b5ab62b60f 146 Pfam PF04308 Ribonuclease H-like 7 143 8.2E-34 T 12-10-2018 IPR007405 Bacteriophage KVP40, Orf299 THERU_05735 14f5a4317f720dd4381466d60142ac51 340 SUPERFAMILY SSF88713 17 295 1.53E-24 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THERU_05735 14f5a4317f720dd4381466d60142ac51 340 Pfam PF01522 Polysaccharide deacetylase 51 161 4.1E-13 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THERU_04890 dee9534e71df3f1ffb069e1b1fca4aac 432 SUPERFAMILY SSF56762 10 432 5.89E-87 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_04890 dee9534e71df3f1ffb069e1b1fca4aac 432 Pfam PF00374 Nickel-dependent hydrogenase 257 431 1.5E-20 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THERU_04890 dee9534e71df3f1ffb069e1b1fca4aac 432 Pfam PF00374 Nickel-dependent hydrogenase 37 117 1.3E-19 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THERU_04890 dee9534e71df3f1ffb069e1b1fca4aac 432 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 37 62 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THERU_04890 dee9534e71df3f1ffb069e1b1fca4aac 432 Gene3D G3DSA:1.10.645.10 1 432 3.4E-92 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THERU_02220 da2ef0d70a2ab1fc4223f7950d827f4e 313 Pfam PF00535 Glycosyl transferase family 2 3 165 2.9E-37 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THERU_02220 da2ef0d70a2ab1fc4223f7950d827f4e 313 SUPERFAMILY SSF53448 1 257 3.94E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_02220 da2ef0d70a2ab1fc4223f7950d827f4e 313 Gene3D G3DSA:3.90.550.10 1 228 2.5E-47 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THERU_05905 f3388ef067abf06fbd01c283d17b1304 927 Pfam PF13429 Tetratricopeptide repeat 218 477 1.7E-48 T 12-10-2018 THERU_05905 f3388ef067abf06fbd01c283d17b1304 927 SUPERFAMILY SSF48452 185 300 1.54E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_05905 f3388ef067abf06fbd01c283d17b1304 927 Pfam PF13432 Tetratricopeptide repeat 66 104 2.3E-4 T 12-10-2018 THERU_04305 e0bdd39779368d8b777e14a3efc6936c 678 Pfam PF12055 Domain of unknown function (DUF3536) 294 491 6.0E-44 T 12-10-2018 IPR021923 Protein of unknown function DUF3536 THERU_04305 e0bdd39779368d8b777e14a3efc6936c 678 Pfam PF03065 Glycosyl hydrolase family 57 79 241 1.6E-20 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 THERU_04305 e0bdd39779368d8b777e14a3efc6936c 678 Gene3D G3DSA:3.20.110.20 2 283 3.8E-30 T 12-10-2018 THERU_04305 e0bdd39779368d8b777e14a3efc6936c 678 SUPERFAMILY SSF88713 1 280 5.75E-55 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THERU_03205 b40799d32aedbad0b2239887f7ef101b 57 SUPERFAMILY SSF69618 2 57 6.28E-9 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THERU_03205 b40799d32aedbad0b2239887f7ef101b 57 Gene3D G3DSA:3.40.50.10090 1 57 8.9E-6 T 12-10-2018 THERU_04870 479da5f9ae4e9f3967dc85d14f6939f4 128 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 3 117 2.0E-38 T 12-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THERU_04870 479da5f9ae4e9f3967dc85d14f6939f4 128 Gene3D G3DSA:3.30.1370.140 2 99 2.0E-22 T 12-10-2018 IPR038527 HupH, C-terminal domain superfamily THERU_04870 479da5f9ae4e9f3967dc85d14f6939f4 128 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 2 119 3.7E-35 T 12-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THERU_06910 42721b1a908c384e760d8ccbfcc03e23 272 Pfam PF03448 MgtE intracellular N domain 206 261 1.0E-7 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THERU_06910 42721b1a908c384e760d8ccbfcc03e23 272 SUPERFAMILY SSF158791 197 261 5.75E-9 T 12-10-2018 THERU_02035 1a7a6a6d1347b9c21f87586ed109fcc0 273 SUPERFAMILY SSF48695 118 264 1.32E-6 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily THERU_02035 1a7a6a6d1347b9c21f87586ed109fcc0 273 SUPERFAMILY SSF47175 58 130 1.77E-5 T 12-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THERU_04385 280ebfbd51aa03c9450d55fc28996d17 293 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 20 149 3.0E-31 T 12-10-2018 IPR013407 CRISPR-associated protein Cmr2 THERU_04385 280ebfbd51aa03c9450d55fc28996d17 293 Gene3D G3DSA:3.30.70.2230 23 171 5.0E-32 T 12-10-2018 THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 2.2E-94 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 237 44.834 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 Pfam PF00696 Amino acid kinase family 6 216 1.4E-29 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 Gene3D G3DSA:3.40.1160.10 2 237 3.6E-80 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 SUPERFAMILY SSF53633 3 236 1.18E-73 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THERU_01900 79b7bc695b117711a544a3be9b7437b4 237 PIRSF PIRSF005650 1 237 4.1E-93 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 THERU_02430 bf101abfb5dac9f6fb7732ddc195fb65 163 Pfam PF00583 Acetyltransferase (GNAT) family 41 116 4.8E-16 T 12-10-2018 IPR000182 GNAT domain THERU_02430 bf101abfb5dac9f6fb7732ddc195fb65 163 SUPERFAMILY SSF55729 3 124 7.77E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase THERU_02430 bf101abfb5dac9f6fb7732ddc195fb65 163 Gene3D G3DSA:3.40.630.30 2 135 5.6E-40 T 12-10-2018 THERU_06345 086876b8f670e288ed4a311353bd996e 133 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 130 8.8E-15 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THERU_07700 0edd63db65f1c6dcaad1c13b89eaf602 94 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 2 87 1.6E-22 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 THERU_04720 49a7ad4170b264b892b8af3085255622 147 Gene3D G3DSA:2.60.40.2470 19 147 1.1E-40 T 12-10-2018 IPR038162 Ig-like SoxY domain superfamily THERU_04720 49a7ad4170b264b892b8af3085255622 147 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 2 147 3.9E-46 T 12-10-2018 IPR016568 Sulphur oxidation, SoxY THERU_04720 49a7ad4170b264b892b8af3085255622 147 PIRSF PIRSF010312 1 147 2.0E-46 T 12-10-2018 IPR016568 Sulphur oxidation, SoxY THERU_04720 49a7ad4170b264b892b8af3085255622 147 Pfam PF13501 Sulfur oxidation protein SoxY 46 146 3.4E-35 T 12-10-2018 IPR032711 Ig-like SoxY domain THERU_02095 76cd93722f49808117303f03946427ae 228 Pfam PF02630 SCO1/SenC 32 137 5.3E-9 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THERU_02095 76cd93722f49808117303f03946427ae 228 Gene3D G3DSA:3.40.30.10 36 200 6.5E-36 T 12-10-2018 THERU_02095 76cd93722f49808117303f03946427ae 228 SUPERFAMILY SSF52833 37 192 3.04E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily THERU_02215 049610520082283126fdd7286b7a07d1 222 Pfam PF03883 Peroxide stress protein YaaA 57 202 4.8E-9 T 12-10-2018 IPR005583 Peroxide stress protein YaaA THERU_00115 c302c5cf4d1db8e5fdadb12452aced55 478 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 46 204 1.4E-33 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like THERU_06090 7ecc9851397aacdd715a697e05f431c1 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 130 1.9E-21 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THERU_08135 8cea67d71d21c72050e348ce0893d21e 313 Pfam PF09376 NurA domain 148 282 1.3E-7 T 12-10-2018 IPR018977 NurA domain THERU_08135 8cea67d71d21c72050e348ce0893d21e 313 SUPERFAMILY SSF53098 13 308 6.83E-53 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily THERU_00220 f71faa0394d2a663b90e5039f9d311b7 130 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 2 120 1.8E-36 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 THERU_00220 f71faa0394d2a663b90e5039f9d311b7 130 PIRSF PIRSF016498 1 130 4.2E-37 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 THERU_06745 6803ca4b73ef6e1d9379c8c9838ac113 77 Pfam PF02325 YGGT family 9 72 5.7E-10 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 THERU_01675 741b298061b52f2e25349bf279f64fd2 164 Pfam PF02620 Uncharacterized ACR, COG1399 55 157 3.9E-18 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD THERU_02690 9881167ab3a19bb810eadf8804ab99f5 169 Pfam PF01724 Domain of unknown function DUF29 11 162 2.8E-40 T 12-10-2018 IPR002636 Protein from unkown function DUF29 THERU_02690 9881167ab3a19bb810eadf8804ab99f5 169 Gene3D G3DSA:1.20.1220.20 5 166 1.3E-24 T 12-10-2018 THERU_03590 6a56b8378f3d56c45c11483889662666 164 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 3 161 1.4E-38 T 12-10-2018 IPR019250 Protein of unknown function DUF2227, metal-binding THERU_07145 ffddb56a7958197a560eeda5089f7324 497 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 14 221 5.2E-28 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 THERU_08335 3b04cbe3da35409afad44084ed894091 190 Gene3D G3DSA:3.40.1280.10 2 190 4.9E-69 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THERU_08335 3b04cbe3da35409afad44084ed894091 190 Pfam PF09936 SAM-dependent RNA methyltransferase 5 185 2.8E-72 T 12-10-2018 IPR019230 RNA methyltransferase domain THERU_05840 e239cc4efc50150c469546b2f0d2935c 111 PIRSF PIRSF006821 1 109 1.5E-52 T 12-10-2018 IPR018685 Protein of unknown function DUF2173 THERU_05840 e239cc4efc50150c469546b2f0d2935c 111 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 4 107 1.5E-41 T 12-10-2018 IPR018685 Protein of unknown function DUF2173 THERU_06855 6ad3b42b10c9211023d8bbfe53cb24e1 208 Pfam PF03963 Flagellar hook capping protein - N-terminal region 22 62 7.3E-6 T 12-10-2018 IPR005648 Flagellar hook capping protein THERU_01695 61775eafe0db35d87cb181644d25208a 182 Pfam PF04368 Protein of unknown function (DUF507) 1 181 1.4E-55 T 12-10-2018 IPR007463 Protein of unknown function DUF507 THERU_06520 3a93c6d22e8c1679d50595013a2ddc34 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 90 235 2.3E-25 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THERU_06520 3a93c6d22e8c1679d50595013a2ddc34 288 SUPERFAMILY SSF52518 42 278 5.63E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold THERU_06520 3a93c6d22e8c1679d50595013a2ddc34 288 Gene3D G3DSA:3.40.50.970 108 287 5.0E-33 T 12-10-2018 THERU_05940 b5fb0da43505f31fe26b070e83b13613 345 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 69 95 5.0E-4 T 12-10-2018 IPR002885 Pentatricopeptide repeat THERU_05920 6696715f6ac5a0db06e22c0b1c2548be 321 SUPERFAMILY SSF81901 211 301 1.94E-6 T 12-10-2018 THERU_05920 6696715f6ac5a0db06e22c0b1c2548be 321 Gene3D G3DSA:1.25.40.10 208 318 1.4E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THERU_03900 bc157e93f9f3dbea6413c046ef3d45af 139 SUPERFAMILY SSF58113 41 120 4.97E-5 T 12-10-2018 THERU_03900 bc157e93f9f3dbea6413c046ef3d45af 139 Gene3D G3DSA:1.20.120.20 30 124 2.4E-7 T 12-10-2018 THERU_02730 5cb5e996b3dd3d13348f5594e717a47a 142 Gene3D G3DSA:1.10.3210.10 30 141 3.2E-6 T 12-10-2018 THERU_01740 2359c346e2a356c2fcaa56dc5523d611 212 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 19 196 2.0E-10 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THERU_06375 f6fe7a1dc0169bf633eee0e70909c1bb 138 Pfam PF06146 Phosphate-starvation-inducible E 58 124 1.5E-9 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like THERU_00245 9c9e20c3efdc8649171e73ed48902c76 238 ProDom PD117176 AQ_1776 3 220 3.0E-92 T 12-10-2018 THERU_03875 daecd75e5d6464c4e2c1c6c344b04be3 123 Pfam PF01934 Protein of unknown function DUF86 15 109 1.2E-27 T 12-10-2018 IPR008201 Protein of unknown function DUF86 THERU_03855 83d7629640022f232cd934a11456ace4 305 Pfam PF01934 Protein of unknown function DUF86 18 130 1.4E-5 T 12-10-2018 IPR008201 Protein of unknown function DUF86 THERU_03855 83d7629640022f232cd934a11456ace4 305 Pfam PF01934 Protein of unknown function DUF86 167 274 2.7E-27 T 12-10-2018 IPR008201 Protein of unknown function DUF86 THERU_00060 521cb0a0244680e6d05f90707d0ef771 89 Pfam PF04316 Anti-sigma-28 factor, FlgM 35 77 1.8E-6 T 12-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal THERU_00060 521cb0a0244680e6d05f90707d0ef771 89 Gene3D G3DSA:1.10.287.1160 50 85 8.7E-6 T 12-10-2018 THERU_00060 521cb0a0244680e6d05f90707d0ef771 89 SUPERFAMILY SSF101498 8 82 1.12E-8 T 12-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily THERU_05425 62cc81b4de316b9ce03a8d815a0dde81 139 SUPERFAMILY SSF82784 18 129 6.02E-30 T 12-10-2018 IPR036102 OsmC/Ohr superfamily THERU_05425 62cc81b4de316b9ce03a8d815a0dde81 139 Pfam PF02566 OsmC-like protein 30 126 5.7E-20 T 12-10-2018 IPR003718 OsmC/Ohr family THERU_05425 62cc81b4de316b9ce03a8d815a0dde81 139 Gene3D G3DSA:3.30.300.20 1 131 1.7E-36 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta THERU_03670 4dbd4c6c125ce75b311eb1eb960f2cd2 164 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 141 10.939 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THERU_03670 4dbd4c6c125ce75b311eb1eb960f2cd2 164 Pfam PF00430 ATP synthase B/B' CF(0) 10 136 1.6E-15 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THERU_04080 07a96d995811c956702409f00d40592f 366 Pfam PF00953 Glycosyl transferase family 4 72 229 1.6E-28 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 THERU_06555 13f2c6f87e5fb97836cd865b6e3b5fd4 46 Gene3D G3DSA:1.20.1640.10 6 46 1.5E-5 T 12-10-2018 THERU_05405 e0ffeff3641607d423ca0cc08305e2a7 132 Pfam PF13664 Domain of unknown function (DUF4149) 10 96 5.9E-15 T 12-10-2018 IPR025423 Domain of unknown function DUF4149 THERU_03545 0ef319c4651cd77402fb5166a0f7bc19 443 SUPERFAMILY SSF56935 103 420 3.3E-7 T 12-10-2018 THERU_06350 7631037f884fc257bb54de9e53686d09 204 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 193 3.8E-28 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THERU_01835 5be332323ee8800c74732b0829a370e5 252 Pfam PF11306 Protein of unknown function (DUF3108) 22 236 1.6E-18 T 12-10-2018 IPR021457 Protein of unknown function DUF3108 THERU_05435 03d4a6e0a7f215a036b034c8d898fdff 195 Pfam PF12007 Protein of unknown function (DUF3501) 4 192 1.9E-66 T 12-10-2018 IPR021890 Protein of unknown function DUF3501 THERU_03960 871c9a1c9d6e08b2485cd90f618183ee 188 Pfam PF04250 Protein of unknown function (DUF429) 5 175 5.6E-14 T 12-10-2018 IPR007362 Protein of unknown function DUF429 THERU_03715 3ed4361e309e680a7a8fbf60d13fb502 77 Pfam PF06195 Protein of unknown function (DUF996) 2 59 5.6E-12 T 12-10-2018 IPR010397 Protein of unknown function DUF996 THERU_02865 c5b4775943f27b408484348aa7bf43da 61 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 2.9E-18 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 THERU_08140 fa7eaa940932f16c4f585cd8e3ddc477 290 Pfam PF03547 Membrane transport protein 1 139 9.8E-17 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 THERU_08140 fa7eaa940932f16c4f585cd8e3ddc477 290 Pfam PF03547 Membrane transport protein 145 281 2.7E-12 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085