locus-tag	class	description
Thein_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Thein_0002	ENOG4105CQB	FAD linked oxidase domain protein
Thein_0003	ENOG4105D05	Receptor
Thein_0005	ENOG4105BZU	Histidine kinase
Thein_0006	ENOG4105C01	Dihydroxy-acid dehydratase
Thein_0007	ENOG41083MR	nifu domain-containing protein
Thein_0008	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Thein_0009	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thein_0010	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Thein_0011	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Thein_0016	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0018	ENOG4105C03	ribonuclease
Thein_0024	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Thein_0028	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Thein_0031	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Thein_0033	ENOG4105EGD	dinuclear metal center protein, YbgI family
Thein_0034	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thein_0035	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Thein_0036	ENOG4105C98	muts2 protein
Thein_0037	ENOG41084JP	30S ribosomal protein S21
Thein_0038	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Thein_0040	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Thein_0042	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Thein_0043	ENOG4105CHM	Aminotransferase
Thein_0044	ENOG4108JIC	nucleoside recognition domain protein
Thein_0045	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Thein_0047	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Thein_0048	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Thein_0049	ENOG4107QYV	phosphohexose isomerase
Thein_0055	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Thein_0057	ENOG4105C5Q	Transcriptional regulator
Thein_0059	ENOG4108UMR	transcriptional regulator AsnC family
Thein_0060	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Thein_0064	ENOG4107SDT	Homocitrate synthase
Thein_0065	ENOG4105G6Z	alkaline phosphatase
Thein_0070	ENOG4105C8V	SAICAR synthetase
Thein_0073	ENOG4105KT7	mgtC SapB transporter
Thein_0074	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Thein_0076	ENOG4105C8B	TIGR00159 family
Thein_0078	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Thein_0079	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0083	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Thein_0084	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Thein_0085	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Thein_0086	ENOG4105KC4	UPF0296 protein
Thein_0087	ENOG4105DSJ	YicC domain protein
Thein_0089	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Thein_0091	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Thein_0093	ENOG4105CJR	Integral membrane protein (MviN
Thein_0098	ENOG4105G5W	regulator Fur family
Thein_0100	ENOG4105C8Q	Methyl-accepting chemotaxis
Thein_0101	ENOG4105C1V	Peptidase, M16
Thein_0102	ENOG4105D1F	ATP-binding protein
Thein_0104	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Thein_0106	ENOG41065RQ	ADP-ribosylation crystallin J1
Thein_0108	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Thein_0114	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Thein_0116	ENOG4105IJJ	transcriptional regulator, crp fnr family
Thein_0117	ENOG41072GX	Peptidase M22 Glycoprotease
Thein_0119	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Thein_0120	ENOG4105VN1	Heat shock protein
Thein_0121	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
Thein_0124	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Thein_0125	ENOG4107XSR	periplasmic solute binding protein
Thein_0126	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Thein_0128	ENOG4105BZU	Histidine kinase
Thein_0129	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Thein_0130	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Thein_0131	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Thein_0133	ENOG4105W49	UPF0434 protein
Thein_0136	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Thein_0138	ENOG4108RZE	Tetr family transcriptional regulator
Thein_0142	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Thein_0143	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Thein_0145	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Thein_0147	ENOG4105C9X	ppx gppa phosphatase
Thein_0148	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Thein_0152	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Thein_0153	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Thein_0154	ENOG4105DZS	Phenylacetate-CoA ligase
Thein_0156	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Thein_0157	ENOG4105HHA	aminodeoxychorismate lyase
Thein_0165	ENOG4108FYC	transcriptional regulator MERR family
Thein_0166	ENOG4108EC8	DNA internalization-related competence protein ComEC
Thein_0169	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Thein_0170	ENOG4105DAN	ATP-dependent protease
Thein_0173	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Thein_0174	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Thein_0175	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Thein_0177	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Thein_0179	ENOG4105X6C	Flagellar basal body-associated protein FliL
Thein_0180	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Thein_0181	ENOG4105DD5	Flagellar motor switch protein
Thein_0183	ENOG4105CN7	Flagellar biosynthetic protein FliP
Thein_0184	ENOG4105VS8	Flagellar biosynthetic protein fliq
Thein_0185	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Thein_0186	ENOG4105D00	flagellar biosynthetic protein flhB
Thein_0187	ENOG4105D7B	Flagellar biosynthesis protein flha
Thein_0188	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Thein_0189	ENOG4107R21	site-determining protein
Thein_0190	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thein_0191	ENOG4108VYJ	response regulator receiver protein
Thein_0197	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Thein_0199	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Thein_0200	ENOG4105E3H	phosphoglycerate mutase
Thein_0201	ENOG4108IYU	L-aspartate oxidase
Thein_0203	ENOG4108YZA	Nitrogen regulatory protein pii
Thein_0207	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Thein_0208	ENOG4105SFS	phosphoesterase RecJ domain protein
Thein_0209	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Thein_0211	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Thein_0211	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Thein_0213	ENOG4105CHV	Transcription elongation factor NusA
Thein_0214	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Thein_0229	ENOG4105DTT	CRISPR-associated helicase, cas3
Thein_0232	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Thein_0233	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Thein_0236	ENOG41087NI	Sulfite exporter TauE/SafE
Thein_0243	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Thein_0245	ENOG4105K59	histidine triad (HIT) protein
Thein_0248	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Thein_0249	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Thein_0250	ENOG4105C32	Amino acid ABC transporter (Permease)
Thein_0251	ENOG4105CP9	extracellular ligand-binding receptor
Thein_0253	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Thein_0254	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Thein_0257	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Thein_0258	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Thein_0260	ENOG4105BZU	Histidine kinase
Thein_0262	ENOG4105CPF	Cell wall formation (By similarity)
Thein_0264	ENOG4105C5I	Dehydrogenase
Thein_0265	ENOG4108EE7	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Thein_0266	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Thein_0267	ENOG4105DFU	Cell wall formation (By similarity)
Thein_0271	ENOG4105BZU	Histidine kinase
Thein_0272	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thein_0273	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thein_0274	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Thein_0275	ENOG4108VZM	50s ribosomal protein L10
Thein_0276	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Thein_0277	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Thein_0278	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Thein_0280	ENOG4105WDJ	50S ribosomal protein L33
Thein_0281	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Thein_0283	ENOG4107QN2	dihydrolipoyl dehydrogenase
Thein_0284	ENOG4105EWK	phytoene
Thein_0287	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Thein_0289	ENOG4105DPX	Hydrogenase, large subunit
Thein_0290	ENOG4105E3S	small subunit
Thein_0291	ENOG4108USZ	hydrogenase
Thein_0296	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Thein_0297	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Thein_0298	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Thein_0301	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Thein_0302	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Thein_0303	ENOG4105CFH	Aspartokinase
Thein_0304	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thein_0311	ENOG4106VK6	Flagellar motor protein
Thein_0312	ENOG4105E14	MotA TolQ exbB proton channel
Thein_0314	ENOG4105DJV	ribulose-phosphate 3-epimerase
Thein_0315	ENOG4105C8Q	Methyl-accepting chemotaxis
Thein_0316	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
Thein_0317	ENOG4105C8W	ABC transporter
Thein_0318	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
Thein_0322	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0327	ENOG4107YZX	Universal stress protein
Thein_0331	ENOG4107YZX	Universal stress protein
Thein_0333	ENOG4107YZX	Universal stress protein
Thein_0334	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Thein_0340	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Thein_0341	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Thein_0342	ENOG41064RH	membrane protein YliF
Thein_0345	ENOG4108V3W	Chemotaxis protein, CheW
Thein_0346	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thein_0347	ENOG4105CBS	Chea signal transduction histidine kinase
Thein_0348	ENOG4105BZU	Histidine kinase
Thein_0349	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Thein_0351	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Thein_0353	ENOG4105CD5	CoA-binding domain protein
Thein_0355	ENOG41090R7	Ferric uptake
Thein_0360	ENOG4105FF2	Type I DHQase
Thein_0361	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Thein_0362	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Thein_0363	ENOG4108UXN	response regulator
Thein_0364	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Thein_0366	ENOG4105F8V	Hydrolase, tatD family
Thein_0367	ENOG4108Z03	MAF-like protein
Thein_0368	ENOG4105SG9	biopolymer transport protein, ExbD
Thein_0370	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Thein_0371	ENOG4105C1G	acyl-Coa dehydrogenase
Thein_0372	ENOG4105BZJ	Electron transfer flavoprotein
Thein_0373	ENOG4105C10	Electron transfer flavoprotein
Thein_0375	ENOG4105CHR	reductase
Thein_0378	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Thein_0380	ENOG4108YZG	isomerase
Thein_0381	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Thein_0382	ENOG4108UK2	deaminase
Thein_0384	ENOG4105E5Q	amino acid AbC transporter
Thein_0385	ENOG4105EAB	amino acid AbC transporter
Thein_0387	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Thein_0389	ENOG4108V9Q	carbonic anhydrase
Thein_0395	ENOG4105BZU	Histidine kinase
Thein_0396	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thein_0397	ENOG4108R6K	riboflavin synthase, subunit alpha
Thein_0398	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Thein_0402	ENOG4105D98	threonine synthase
Thein_0404	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
Thein_0405	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
Thein_0408	ENOG4105CXV	gliding motility protein
Thein_0410	ENOG4107QHF	type ii secretion system protein e
Thein_0411	ENOG4105BZU	Histidine kinase
Thein_0412	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0415	ENOG4105D63	family UPF0324
Thein_0417	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Thein_0429	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Thein_0430	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Thein_0432	ENOG4105D4A	Cell wall formation (By similarity)
Thein_0433	ENOG4105DFU	Cell wall formation (By similarity)
Thein_0434	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Thein_0435	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Thein_0436	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Thein_0437	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Thein_0438	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Thein_0441	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Thein_0442	ENOG4108V6E	Cell division protein mraZ
Thein_0445	ENOG4105C5E	polysaccharide biosynthesis protein
Thein_0446	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Thein_0447	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Thein_0448	ENOG4105F0R	Cytidylyltransferase
Thein_0449	ENOG4105D2T	synthase
Thein_0451	ENOG4105I03	Flagellin
Thein_0454	ENOG4105DTS	flagellar hook-associated
Thein_0455	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Thein_0457	ENOG4105DTJ	flagellar hook-associated protein
Thein_0458	ENOG4105E1Q	flagellar hook-associated protein
Thein_0458	ENOG4105E1Q	flagellar hook-associated protein
Thein_0461	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Thein_0462	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Thein_0463	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Thein_0465	ENOG4105CGA	flagellar basal-body rod protein FlgG
Thein_0466	ENOG4105KTQ	flagellar basal-body rod protein
Thein_0468	ENOG4105D1F	ATP-binding protein
Thein_0468	ENOG4105D1F	ATP-binding protein
Thein_0469	ENOG4107QMS	site-determining protein
Thein_0471	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Thein_0472	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Thein_0473	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Thein_0474	ENOG4105CAS	nag kinase
Thein_0479	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Thein_0481	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Thein_0482	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Thein_0483	ENOG4105BZU	Histidine kinase
Thein_0484	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0486	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Thein_0488	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Thein_0489	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
Thein_0491	ENOG4108IJ0	Aspartate ammonia-lyase
Thein_0495	ENOG4107QHI	-hydrogenase
Thein_0498	ENOG4107QHI	-hydrogenase
Thein_0499	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Thein_0500	ENOG4107QW8	radical SAM domain protein
Thein_0502	ENOG4108HUF	Transporter
Thein_0503	ENOG4105EHG	Permease protein
Thein_0504	ENOG4108HWH	(ABC) transporter
Thein_0509	ENOG4107R56	PP-loop domain protein
Thein_0510	ENOG4107S2Z	UPF0761 membrane protein
Thein_0511	ENOG4105E4G	Type IV pilus
Thein_0516	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Thein_0517	ENOG4105C3F	Signal peptidase i
Thein_0519	ENOG410620I	Diguanylate cyclase
Thein_0522	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Thein_0523	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Thein_0533	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Thein_0534	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Thein_0536	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Thein_0537	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Thein_0538	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Thein_0539	ENOG4105BZU	Histidine kinase
Thein_0540	ENOG4105CFG	Acts as a chaperone (By similarity)
Thein_0541	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Thein_0543	ENOG4105EAD	ABC transporter
Thein_0544	ENOG4105DRP	amino acid AbC transporter
Thein_0545	ENOG4105CDA	abc transporter atp-binding protein
Thein_0548	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Thein_0550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Thein_0552	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Thein_0553	ENOG41082DI	50s ribosomal protein l31
Thein_0554	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Thein_0555	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Thein_0556	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Thein_0557	ENOG4105CDH	Citrulline--aspartate ligase
Thein_0558	ENOG4105EAH	synthase
Thein_0559	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Thein_0562	ENOG4105BZU	Histidine kinase
Thein_0563	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Thein_0564	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Thein_0566	ENOG4105KJJ	Uncharacterized ACR, COG1993
Thein_0567	ENOG4105WMR	Protein CrcB homolog
Thein_0568	ENOG4107G9V	glycosyl transferase, family 39
Thein_0571	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Thein_0572	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Thein_0576	ENOG4105CTK	cobaltochelatase, cobn subunit
Thein_0577	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Thein_0579	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Thein_0580	ENOG4105VB9	50S ribosomal protein l28
Thein_0581	ENOG4105CDU	Replicative dna helicase
Thein_0583	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Thein_0584	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Thein_0587	ENOG4105FA2	dna polymerase iii
Thein_0588	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Thein_0589	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Thein_0591	ENOG4105C9M	aspartyl-trna synthetase
Thein_0594	ENOG41088YS	Glycosyl transferase (Group 1
Thein_0596	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Thein_0597	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Thein_0598	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Thein_0600	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Thein_0601	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Thein_0603	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Thein_0604	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Thein_0606	ENOG4105CRK	lysyL-tRNA synthetase
Thein_0607	ENOG4105C4R	Atp-dependent dna helicase
Thein_0611	ENOG4107T5V	SNARE associated Golgi
Thein_0613	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Thein_0616	ENOG4105F7J	membrane-bound serine protease
Thein_0617	ENOG4105DUM	transcriptional regulator, lysR family
Thein_0618	ENOG4105CB5	ATP-dependent DNA helicase recG
Thein_0620	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Thein_0624	ENOG4105VFE	sira family
Thein_0625	ENOG4105CUC	YeeE YedE family protein
Thein_0626	ENOG4105C1V	Peptidase, M16
Thein_0630	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Thein_0632	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Thein_0633	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Thein_0634	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Thein_0635	ENOG41085QA	50S ribosomal protein l34
Thein_0637	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Thein_0643	ENOG41080R2	UPF0102 protein
Thein_0645	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Thein_0646	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Thein_0647	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Thein_0649	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Thein_0651	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
Thein_0658	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Thein_0659	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Thein_0660	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Thein_0663	ENOG4105C8M	UPF0272 protein
Thein_0665	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Thein_0669	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Thein_0670	ENOG4105C8N	cysteinyl-tRNA synthetase
Thein_0671	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_0672	ENOG4105BZU	Histidine kinase
Thein_0674	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Thein_0675	ENOG4105BZ7	extracellular solute-binding protein family 1
Thein_0676	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Thein_0678	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Thein_0681	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Thein_0682	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Thein_0683	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Thein_0684	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Thein_0685	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
Thein_0690	ENOG4106WTF	Glycosyl transferase, family 2
Thein_0693	ENOG4105BZ1	(ABC) transporter
Thein_0695	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Thein_0696	ENOG4105C37	(CBS) domain
Thein_0700	ENOG4108XHF	Pfam:DUF178
Thein_0702	ENOG41071TK	Uncharacterised protein family (UPF0150)
Thein_0708	ENOG4107QPH	glycogen) synthase
Thein_0709	ENOG4105CAQ	asparagine synthetase
Thein_0710	ENOG4107TYR	Glycosyl Transferase
Thein_0713	ENOG4105D3Q	Sugar transferase
Thein_0715	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
Thein_0727	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Thein_0729	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Thein_0735	ENOG4105D2T	synthase
Thein_0736	ENOG4105F0R	Cytidylyltransferase
Thein_0743	ENOG4105CDY	transcriptional regulatory protein
Thein_0744	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Thein_0745	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Thein_0746	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Thein_0747	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Thein_0750	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
Thein_0752	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Thein_0754	ENOG4105CZA	synthase
Thein_0755	ENOG4105CHM	Aminotransferase
Thein_0758	ENOG4107SC1	transglycosylase
Thein_0760	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Thein_0761	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Thein_0762	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Thein_0763	ENOG4105DX0	Hemolysin A
Thein_0764	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Thein_0765	ENOG4108JQC	penicillin-binding protein 1A
Thein_0768	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Thein_0770	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Thein_0772	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Thein_0774	ENOG4105C8N	cysteinyl-tRNA synthetase
Thein_0776	ENOG4105DXN	mazG family
Thein_0778	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
Thein_0779	ENOG4108JQ7	(ABC) transporter
Thein_0788	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Thein_0790	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
Thein_0791	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Thein_0793	ENOG4105CNU	cell division protein FtsK
Thein_0798	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Thein_0799	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Thein_0801	ENOG4105JVV	
Thein_0807	ENOG4107QZM	n-acetylglutamate synthase
Thein_0809	ENOG4105C75	arginyL-tRNA synthetase
Thein_0814	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Thein_0816	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thein_0818	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Thein_0819	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Thein_0821	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Thein_0823	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Thein_0824	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Thein_0829	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Thein_0830	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Thein_0831	ENOG4105KPV	Transcriptional regulator
Thein_0832	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Thein_0833	ENOG4107QZB	decarboxylase
Thein_0834	ENOG4108N5B	2-phosphosulfolactate phosphatase
Thein_0837	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Thein_0839	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Thein_0840	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Thein_0841	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Thein_0842	ENOG4105VPX	protein, conserved in bacteria
Thein_0844	ENOG4105DDQ	anthranilate synthase
Thein_0845	ENOG4105CRQ	synthase (Component I)
Thein_0846	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
Thein_0849	ENOG4105CW7	secretion protein, HlyD family
Thein_0850	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Thein_0852	ENOG4105NBF	ammecr1 domain protein
Thein_0854	ENOG4105C5R	Aminotransferase
Thein_0859	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Thein_0860	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Thein_0862	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Thein_0863	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Thein_0864	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Thein_0865	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Thein_0867	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Thein_0872	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Thein_0876	ENOG4107QI6	Cysteine desulfurase
Thein_0879	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
Thein_0881	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Thein_0882	ENOG4108JA2	transcriptioN-repair coupling factor
Thein_0883	ENOG4105BZU	Histidine kinase
Thein_0884	ENOG4105K46	50S ribosomal protein l27
Thein_0885	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Thein_0888	ENOG4105CTQ	phosphohexokinase
Thein_0889	ENOG4105ECP	epimerase
Thein_0890	ENOG4105BZU	Histidine kinase
Thein_0893	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
Thein_0895	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Thein_0896	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
Thein_0897	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Thein_0900	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thein_0901	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Thein_0903	ENOG4105C37	(CBS) domain
Thein_0904	ENOG4105C37	(CBS) domain
Thein_0905	ENOG4105F4G	Membrane
Thein_0906	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Thein_0907	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Thein_0909	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Thein_0910	ENOG4105BZU	Histidine kinase
Thein_0915	ENOG4108ZAI	phosphatidylglycerophosphatase a
Thein_0917	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Thein_0919	ENOG4105EYU	Glutamine amido-transferase
Thein_0920	ENOG4105CBC	glutamate synthase
Thein_0921	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Thein_0926	ENOG4105W3S	hemerythrin-like, metal-binding protein
Thein_0927	ENOG4105E9H	Lytic Murein transglycosylase
Thein_0928	ENOG4107Y9E	nuclease
Thein_0929	ENOG4105CQC	Prephenate dehydratase
Thein_0932	ENOG4107ZYR	domain protein
Thein_0933	ENOG4105CZN	Potassium uptake protein
Thein_0934	ENOG4107RY6	amino acid
Thein_0935	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Thein_0938	ENOG4105C4R	Atp-dependent dna helicase
Thein_0942	ENOG4108JUA	Transcriptional regulator
Thein_0943	ENOG4105DJ0	Poly(A) Polymerase
Thein_0947	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Thein_0948	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Thein_0949	ENOG4107QYG	anthranilate phosphoribosyltransferase
Thein_0950	ENOG4105C3G	gtp-binding protein
Thein_0951	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Thein_0954	ENOG4108KB0	deacetylase
Thein_0955	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Thein_0957	ENOG4105D49	3-dehydroquinate synthase
Thein_0958	ENOG4105N14	lysine exporter protein LysE YggA
Thein_0964	ENOG4105D5G	Transposase
Thein_0969	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Thein_0970	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Thein_0972	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Thein_0973	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Thein_0977	ENOG4105FA0	parb-like partition protein
Thein_0978	ENOG4107QJE	Chromosome Partitioning Protein
Thein_0980	ENOG4105K6T	rare lipoprotein A
Thein_0981	ENOG4108JQ7	(ABC) transporter
Thein_0982	ENOG4105C3U	ABC transporter
Thein_0983	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Thein_0984	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Thein_0985	ENOG4105DEF	Extracellular solute-binding protein, family 5
Thein_0986	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Thein_0987	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Thein_0988	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Thein_0989	ENOG4107TH8	cina domain protein
Thein_0991	ENOG4105CD3	dihydroorotase
Thein_0992	ENOG4105CXT	aspartate transcarbamylase
Thein_0993	ENOG41090A1	ferritin
Thein_0994	ENOG4105C8Y	Acetylornithine aminotransferase
Thein_0995	ENOG4105VEQ	Cold shock protein
Thein_0996	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Thein_0998	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Thein_0999	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Thein_1001	ENOG41061AI	Protein of unknown function (DUF2905)
Thein_1002	ENOG4105WPN	DNA integration recombination invertion protein
Thein_1003	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Thein_1004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Thein_1008	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
Thein_1011	ENOG4108JJB	ABC transporter
Thein_1013	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Thein_1014	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Thein_1016	ENOG4107ZTM	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Thein_1020	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Thein_1023	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Thein_1024	ENOG4105MJ2	Competence protein
Thein_1025	ENOG4105C0H	protease
Thein_1029	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Thein_1030	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Thein_1031	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Thein_1032	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Thein_1033	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Thein_1034	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Thein_1036	ENOG4108MGF	sugar kinase
Thein_1037	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Thein_1039	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Thein_1040	ENOG4105C8Q	Methyl-accepting chemotaxis
Thein_1041	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Thein_1044	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Thein_1045	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Thein_1046	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Thein_1047	ENOG4108JUA	Transcriptional regulator
Thein_1048	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Thein_1049	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Thein_1050	ENOG4108YZA	Nitrogen regulatory protein pii
Thein_1051	ENOG4108YZA	Nitrogen regulatory protein pii
Thein_1052	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Thein_1054	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
Thein_1055	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
Thein_1058	ENOG4105CGK	Exodeoxyribonuclease III
Thein_1059	ENOG4105CN9	Peptidase m42 family protein
Thein_1061	ENOG4105BZU	Histidine kinase
Thein_1062	ENOG4105CAY	ferredoxin--nadp reductase
Thein_1064	ENOG4105DB7	PHP domain protein
Thein_1065	ENOG4105FE9	pseudouridine synthase
Thein_1066	ENOG4105DTN	riboflavin biosynthesis protein ribF
Thein_1068	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Thein_1070	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Thein_1071	ENOG4105C98	muts2 protein
Thein_1073	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Thein_1074	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Thein_1075	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Thein_1076	ENOG4105CRE	cytochrome C
Thein_1079	ENOG4105C32	Amino acid ABC transporter (Permease)
Thein_1080	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Thein_1081	ENOG4105E2K	Glycosyl transferase (Group 1
Thein_1082	ENOG4108ZJ4	polysaccharide deacetylase
Thein_1085	ENOG4105C9B	Cysteine desulfurase
Thein_1090	ENOG4105DB1	molybdopterin oxidoreductase
Thein_1093	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Thein_1096	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Thein_1098	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Thein_1104	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Thein_1105	ENOG4105DBV	ornithine carbamoyltransferase
Thein_1110	ENOG4105DR4	Methyltransferase
Thein_1111	ENOG4105DCG	PHP domain protein
Thein_1114	ENOG4107S0N	DJ-1 family
Thein_1121	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Thein_1123	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Thein_1124	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Thein_1125	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Thein_1126	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Thein_1132	ENOG4105CUY	Mechanosensitive ion channel
Thein_1133	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Thein_1136	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Thein_1137	ENOG4105CQM	Urea amidohydrolase subunit alpha
Thein_1139	ENOG4108YZ9	Urea amidohydrolase subunit gamma
Thein_1140	ENOG4108JUA	Transcriptional regulator
Thein_1141	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Thein_1142	ENOG4105C32	Amino acid ABC transporter (Permease)
Thein_1144	ENOG4105C0Z	ABC transporter
Thein_1145	ENOG4108IV0	ABC, transporter
Thein_1148	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Thein_1156	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Thein_1159	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Thein_1160	ENOG4105C0Z	ABC transporter
Thein_1162	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1163	ENOG4105ES5	Histidine kinase
Thein_1165	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
Thein_1167	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Thein_1170	ENOG4105EHZ	conserved protein UCP016719
Thein_1173	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Thein_1174	ENOG41080Z8	PHOSPHOCARRIER protein
Thein_1179	ENOG4105DHJ	ABC, transporter
Thein_1180	ENOG4105CY3	ABC transporter, permease
Thein_1184	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Thein_1188	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Thein_1194	ENOG4105BZU	Histidine kinase
Thein_1195	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Thein_1197	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Thein_1198	ENOG4105C34	Pseudouridine synthase
Thein_1203	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Thein_1204	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Thein_1205	ENOG4105CFG	Acts as a chaperone (By similarity)
Thein_1206	ENOG4106H78	methyltransferase
Thein_1207	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Thein_1209	ENOG4107W7X	Aldolase
Thein_1210	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Thein_1214	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Thein_1218	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Thein_1224	ENOG4107V1M	polysaccharide export protein
Thein_1226	ENOG4105DVY	radical SAM domain protein
Thein_1227	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Thein_1228	ENOG4105C5X	domain protein
Thein_1229	ENOG4105C3M	thioredoxin reductase
Thein_1230	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Thein_1232	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Thein_1233	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Thein_1234	ENOG4105C6E	dna polymerase iii
Thein_1241	ENOG4105K5M	30s ribosomal protein S16
Thein_1242	ENOG4105VB6	UPF0109 protein
Thein_1243	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Thein_1244	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Thein_1245	ENOG4105DIW	FeS assembly protein SUFB
Thein_1247	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Thein_1248	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Thein_1251	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Thein_1253	ENOG4108JUB	Transcriptional regulator
Thein_1258	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Thein_1261	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Thein_1262	ENOG4105CY0	Metallo-Beta-Lactamase
Thein_1267	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Thein_1268	ENOG4105D48	metallophosphoesterase
Thein_1269	ENOG41090R7	Ferric uptake
Thein_1279	ENOG4105C2X	Arabinose 5-phosphate isomerase
Thein_1280	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Thein_1281	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Thein_1282	ENOG4105C0P	Mg chelatase subunit ChlI
Thein_1283	ENOG4105F4P	)-transporter
Thein_1285	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Thein_1286	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Thein_1287	ENOG4105E02	MotA TolQ exbB proton channel
Thein_1288	ENOG4105E63	Pfam:DUF178
Thein_1290	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Thein_1291	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Thein_1292	ENOG4105E2Z	phosphate ABC transporter (Permease
Thein_1293	ENOG4105C8U	phosphate abc transporter
Thein_1298	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Thein_1300	ENOG4105CH7	arginosuccinase
Thein_1301	ENOG4105CUT	histidyl-tRNA synthetase
Thein_1306	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
Thein_1307	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Thein_1311	ENOG4105D16	lipopolysaccharide heptosyltransferase i
Thein_1312	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Thein_1313	ENOG4105XA0	heptosyltransferase ii
Thein_1314	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Thein_1315	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Thein_1316	ENOG4105BZU	Histidine kinase
Thein_1318	ENOG4105ECY	inositol monophosphatase
Thein_1319	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Thein_1320	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Thein_1321	ENOG410828M	hemerythrin-like, metal-binding protein
Thein_1322	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Thein_1323	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Thein_1324	ENOG4105DFF	Rod shape-determining protein mreb
Thein_1325	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Thein_1327	ENOG4105CJN	penicillin-binding protein
Thein_1328	ENOG4105CNI	cell division protein FtsW
Thein_1331	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Thein_1332	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Thein_1333	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Thein_1334	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Thein_1335	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Thein_1337	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Thein_1349	ENOG41062VX	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Thein_1352	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Thein_1354	ENOG4105DVM	PP-loop domain protein
Thein_1356	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Thein_1357	ENOG4105CIZ	coA-substrate-specific enzyme activase
Thein_1362	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Thein_1366	ENOG4107QHI	-hydrogenase
Thein_1367	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Thein_1368	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Thein_1369	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Thein_1370	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1371	ENOG4105CJ1	ABC, transporter
Thein_1373	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Thein_1374	ENOG4108UJD	30S ribosomal protein S9
Thein_1375	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Thein_1376	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Thein_1378	ENOG4105D05	Receptor
Thein_1380	ENOG4105BZU	Histidine kinase
Thein_1381	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Thein_1382	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Thein_1384	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Thein_1385	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Thein_1387	ENOG4105ERG	peptidase m48, ste24p
Thein_1388	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Thein_1389	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Thein_1392	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
Thein_1395	ENOG4105CUZ	uba thif-type nad fad binding protein
Thein_1397	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Thein_1398	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Thein_1400	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Thein_1401	ENOG4108IUZ	ABC transporter
Thein_1402	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Thein_1404	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Thein_1405	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Thein_1407	ENOG410801F	ribosomal-protein-alanine acetyltransferase
Thein_1409	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Thein_1410	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Thein_1411	ENOG4105BZA	Phosphoglycerate kinase
Thein_1412	ENOG4105CP7	Triose-phosphate isomerase
Thein_1413	ENOG4107EJC	Preprotein translocase subunit SecG
Thein_1414	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Thein_1415	ENOG4105CRE	cytochrome C
Thein_1417	ENOG4105EYW	Ion transport protein
Thein_1420	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Thein_1421	ENOG4105DDK	oxidoreductase, beta subunit
Thein_1422	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Thein_1424	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Thein_1426	ENOG4105GN4	DNA ligase
Thein_1427	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Thein_1431	ENOG4108ZHR	arsR family transcriptional regulator
Thein_1433	ENOG4108YZT	Adenosylcobinamide kinase
Thein_1434	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
Thein_1451	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
Thein_1454	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Thein_1455	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Thein_1458	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Thein_1459	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Thein_1460	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Thein_1461	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Thein_1462	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Thein_1463	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Thein_1464	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Thein_1465	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Thein_1466	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Thein_1467	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Thein_1468	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Thein_1469	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Thein_1470	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Thein_1471	ENOG41082SA	50s ribosomal protein l29
Thein_1472	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Thein_1473	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Thein_1474	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Thein_1475	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Thein_1476	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Thein_1477	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Thein_1478	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Thein_1479	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Thein_1480	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Thein_1481	ENOG4105VPB	50S ribosomal protein L30
Thein_1482	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Thein_1483	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Thein_1484	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Thein_1486	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Thein_1487	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Thein_1488	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Thein_1489	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Thein_1490	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Thein_1491	ENOG4108ZT0	50S ribosomal protein l17
Thein_1492	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Thein_1493	ENOG4105D1H	recombination factor protein RarA
Thein_1494	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Thein_1496	ENOG4105BZU	Histidine kinase
Thein_1505	ENOG4105CFI	type iii restriction protein res subunit
Thein_1514	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Thein_1515	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Thein_1516	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Thein_1517	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Thein_1518	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Thein_1519	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Thein_1521	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Thein_1522	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Thein_1524	ENOG4105CPK	Glycosyl transferase (Group 1
Thein_1525	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Thein_1526	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Thein_1527	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Thein_1528	ENOG4107YZX	Universal stress protein
Thein_1530	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Thein_1531	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Thein_1532	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Thein_1533	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Thein_1534	ENOG4108UVJ	appr-1-p processing domain protein
Thein_1535	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Thein_1536	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Thein_1537	ENOG4105DR5	peptidase
Thein_1539	ENOG4105CTB	Polyprenyl synthetase
Thein_1540	ENOG4105EEQ	Na H antiporter
Thein_1541	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Thein_1546	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Thein_1552	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Thein_1554	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Thein_1558	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Thein_1561	ENOG4105DFM	M18 family aminopeptidase
Thein_1566	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Thein_1567	ENOG4108RAC	Rubrerythrin
Thein_1571	ENOG4105DZR	Type I site-specific deoxyribonuclease
Thein_1574	ENOG4105EKX	Restriction modification system DNA (Specificity
Thein_1577	ENOG4105DFS	Conserved Protein
Thein_1578	ENOG4105CVR	type I restriction-modification system
Thein_1583	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thein_1585	ENOG4105C79	DNA protecting protein DprA
Thein_1586	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Thein_1588	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Thein_1589	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Thein_1592	ENOG4105C22	threonyL-tRNA synthetase
Thein_1593	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Thein_1594	ENOG4105VJV	50s ribosomal protein L35
Thein_1595	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Thein_1596	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Thein_1597	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Thein_1598	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Thein_1601	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Thein_1602	ENOG4105CG5	Glycosyl transferase (Group 1
Thein_1608	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Thein_1612	ENOG4105N5T	Radical SAM Protein
Thein_1615	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Thein_1616	ENOG4105DJZ	UPF0182 protein
Thein_1618	ENOG4105BZU	Histidine kinase
Thein_1619	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1622	ENOG4107QY8	reductase
Thein_1623	ENOG4105QAX	Iron-sulfur
Thein_1624	ENOG4105QAX	Iron-sulfur
Thein_1625	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Thein_1627	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Thein_1628	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Thein_1629	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Thein_1630	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Thein_1632	ENOG4108373	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Thein_1633	ENOG4105D65	subunit l
Thein_1634	ENOG4105C8S	subunit m
Thein_1636	ENOG4105CEY	Amp-dependent synthetase and ligase
Thein_1638	ENOG4105DFA	alanine racemase domain protein
Thein_1640	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Thein_1641	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Thein_1642	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Thein_1643	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Thein_1646	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Thein_1647	ENOG4107Z6A	sulfate abc transporter permease
Thein_1652	ENOG4105CJ1	ABC, transporter
Thein_1656	ENOG4105CRQ	synthase (Component I)
Thein_1658	ENOG4105C3U	ABC transporter
Thein_1659	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Thein_1661	ENOG4105DEF	Extracellular solute-binding protein, family 5
Thein_1662	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Thein_1663	ENOG4108W2P	Methyl-accepting chemotaxis
Thein_1667	ENOG4105DHT	Metal Dependent Phosphohydrolase
Thein_1670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Thein_1671	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
Thein_1672	ENOG4107EF8	Glycosyl transferase (Group 1
Thein_1674	ENOG4105DR5	peptidase
Thein_1675	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Thein_1676	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Thein_1677	ENOG4105D0M	Protease HtpX homolog
Thein_1679	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Thein_1680	ENOG4107ZMQ	sugar fermentation stimulation protein
Thein_1682	ENOG4105CMR	udp-glucose 4-epimerase
Thein_1683	ENOG4105D52	delta-aminolevulinic acid dehydratase
Thein_1685	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Thein_1686	ENOG4108UUM	single-stranded DNA-binding protein
Thein_1687	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Thein_1688	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Thein_1689	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Thein_1690	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Thein_1691	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Thein_1692	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Thein_1695	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Thein_1696	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Thein_1699	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Thein_1700	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Thein_1701	ENOG4105D00	flagellar biosynthetic protein flhB
Thein_1702	ENOG4105C03	ribonuclease
Thein_1708	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Thein_1712	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Thein_1714	ENOG4105CSA	Coproporphyrinogen iii oxidase
Thein_1716	ENOG4105EST	Metal Dependent Phosphohydrolase
Thein_1717	ENOG4105C2M	dna polymerase I
Thein_1719	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Thein_1720	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Thein_1721	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Thein_1722	ENOG41084CW	50S ribosomal protein L32
Thein_1723	ENOG4105KNH	Nucleic acid-binding protein
Thein_1728	ENOG4105C0H	protease
Thein_1730	ENOG4105K4P	CoA-binding domain protein
Thein_1736	ENOG4105CAQ	asparagine synthetase
Thein_1737	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Thein_1750	ENOG4107QPH	glycogen) synthase
Thein_1751	ENOG4105K64	Glycosyl transferase, family 2
Thein_1762	ENOG4105G6Z	alkaline phosphatase
Thein_1770	ENOG4105C9A	Phoh family
Thein_1774	ENOG4105VZ9	UPF0235 protein
Thein_1775	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Thein_1776	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Thein_1785	ENOG4108USZ	hydrogenase
Thein_1804	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Thein_1806	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1808	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1809	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Thein_1810	ENOG4108ZC9	flagellar basal-body rod protein flgc
Thein_1811	ENOG41084DA	flagellar hook-basal body complex protein fliE
Thein_1812	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Thein_1813	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Thein_1814	ENOG4105W2B	Flagellar assembly protein
Thein_1820	ENOG4105QAX	Iron-sulfur
Thein_1827	ENOG4105C8T	Leucyl-tRNA synthetase
Thein_1828	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Thein_1831	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_1832	ENOG4107TUY	Histidine kinase
Thein_1836	ENOG4105K8N	protein family UPF0079, ATPase
Thein_1837	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Thein_1838	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Thein_1841	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Thein_1842	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Thein_1844	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Thein_1845	ENOG4105VCQ	rubredoxin
Thein_1849	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Thein_1850	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Thein_1851	ENOG4108VJ1	Transcriptional regulator (CarD family
Thein_1852	ENOG4105CTP	PilT protein domain protein
Thein_1853	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Thein_1854	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Thein_1855	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Thein_1858	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Thein_1859	ENOG4105C0Z	ABC transporter
Thein_1862	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Thein_1864	ENOG4105FDK	ABC transporter
Thein_1866	ENOG4105M6F	mutator MutT protein
Thein_1867	ENOG4105C83	adenylosuccinate lyase
Thein_1868	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Thein_1869	ENOG4105C34	Pseudouridine synthase
Thein_1877	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Thein_1879	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Thein_1886	ENOG4105D7Q	type ii secretion system
Thein_1887	ENOG4107QHF	type ii secretion system protein e
Thein_1890	ENOG4105CPN	adenine deaminase
Thein_1891	ENOG4105C7N	Xanthine uracil vitamin C permease
Thein_1892	ENOG4107NFR	Fructose-1,6-bisphosphatase
Thein_1896	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Thein_1897	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Thein_1898	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Thein_1900	ENOG4105EHG	Permease protein
Thein_1901	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Thein_1904	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Thein_1905	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Thein_1906	ENOG41081F0	Precorrin-8x methylmutase
Thein_1908	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Thein_1909	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Thein_1910	ENOG4105W5Q	DNA repair protein (RadC
Thein_1911	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Thein_1912	ENOG4108Z6B	deaminase
Thein_1915	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Thein_1916	ENOG4105CGY	Dna recombination protein
Thein_1918	ENOG4105C7K	acetolactate synthase
Thein_1919	ENOG4108ZP8	Acetolactate synthase small subunit
Thein_1921	ENOG4105E2X	shikimate dehydrogenase
Thein_1922	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Thein_1923	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Thein_1950	ENOG4108UUM	single-stranded DNA-binding protein
Thein_1980	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Thein_1981	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Thein_1982	ENOG4105C1A	potassium transporter peripheral membrane
Thein_1983	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Thein_1985	ENOG4107GFK	fumarate
Thein_1986	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Thein_1987	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Thein_1988	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Thein_1989	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Thein_1995	ENOG4109015	Biopolymer transport protein exbD tolR
Thein_2002	ENOG4108JJB	ABC transporter
Thein_2009	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Thein_2010	ENOG4105CQS	hydrogenase expression formation protein HypD
Thein_2013	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Thein_2014	ENOG4105E3H	phosphoglycerate mutase
Thein_2017	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Thein_2018	ENOG4105F4R	Transcriptional regulator mode
Thein_2019	ENOG4105CD5	CoA-binding domain protein
Thein_2022	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Thein_2024	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Thein_2025	ENOG4105CQB	FAD linked oxidase domain protein
Thein_2026	ENOG4105CH5	extracellular solute-binding protein, family 7
Thein_2028	ENOG4108VDT	Glycosyl transferase family protein
Thein_2029	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Thein_2030	ENOG4105VCQ	rubredoxin
Thein_2031	ENOG4105C0B	DNA polymerase III (alpha subunit)
Thein_2036	ENOG4107S1Q	Phosphatase
Thein_2038	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Thein_2039	ENOG4105DJ0	Poly(A) Polymerase
Thein_2040	ENOG4108Z4T	Peptidase M50
Thein_2043	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
Thein_2045	ENOG4107RFW	hydrolase family 57
Thein_2048	ENOG4105D64	Mechanosensitive ion channel
Thein_2050	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Thein_2051	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Thein_2053	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Thein_2054	ENOG4105CH2	amidohydrolase
Thein_2055	ENOG4105MAX	Superoxide reductase
Thein_2056	ENOG4105CNW	domain protein
Thein_2058	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Thein_2060	ENOG4108T9Q	UPF0278 protein
Thein_2061	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
Thein_2062	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_2063	ENOG4105BZU	Histidine kinase
Thein_2064	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Thein_2065	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Thein_2067	ENOG4107TSN	permease
Thein_2069	ENOG4105EWK	phytoene
Thein_2073	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Thein_2079	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Thein_2081	ENOG4105CGH	5'-nucleotidase
Thein_2083	ENOG4108UW5	maltose o-acetyltransferase
Thein_2084	ENOG4105C0Z	ABC transporter
Thein_2085	ENOG4108IV0	ABC, transporter
Thein_2086	ENOG4105DZS	Phenylacetate-CoA ligase
Thein_2088	ENOG4105DZP	Membrane-associated zinc metalloprotease
Thein_2089	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Thein_2090	ENOG4105KNE	Phosphatidate cytidylyltransferase
Thein_2092	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Thein_2093	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Thein_2094	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Thein_2095	ENOG4105CE9	30S ribosomal protein S2
Thein_2096	ENOG4105BZE	flagellar hook protein, FlgE
Thein_2097	ENOG4105BZE	flagellar hook protein, FlgE
Thein_2100	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Thein_2102	ENOG4107RBS	Methyltransferase
Thein_2105	ENOG4105C31	Tryptophanyl-tRNA synthetase
Thein_2107	ENOG4108Z4U	Ferredoxin
Thein_2110	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Thein_2111	ENOG4105EM7	Selenocysteine-specific translation elongation factor
Thein_2114	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Thein_2118	ENOG4105K64	Glycosyl transferase, family 2
Thein_2120	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Thein_2121	ENOG4105MA4	psp1 domain protein
Thein_2123	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Thein_2124	ENOG4107QHF	type ii secretion system protein e
Thein_2125	ENOG4108VAU	general secretion pathway protein G
Thein_2133	ENOG4105GVR	general secretion pathway protein D
Thein_2136	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Thein_2138	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Thein_2140	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Thein_2142	ENOG4105CZX	twitching motility protein
Thein_2143	ENOG4105CZX	twitching motility protein
Thein_2144	ENOG4105CAK	Cell division ATP-binding protein ftsE
Thein_2146	ENOG41063SB	peptidase
Thein_2147	ENOG4105CN1	protease
Thein_2148	ENOG4105PXI	polysaccharide deacetylase
Thein_2149	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Thein_2150	ENOG4105CAT	Cytidine monophosphate kinase
Thein_2151	ENOG4105CKK	Glycosyl transferase, family 2
Thein_2154	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Thein_2155	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Thein_2156	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Thein_2157	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Thein_2159	ENOG4105F38	ABC transporter, permease
Thein_2161	ENOG4107RUE	extracellular solute-binding protein family 1
Thein_2163	ENOG41060K3	Methyltransferase
Thein_2166	ENOG4105C8Q	Methyl-accepting chemotaxis
Thein_2168	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Thein_2169	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Thein_2170	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Thein_2172	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Thein_2173	ENOG41082X2	rubredoxin
Thein_2178	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Thein_2182	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
Thein_2183	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
Thein_2184	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
Thein_2190	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Thein_2191	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Thein_2192	ENOG4105CKU	formyltetrahydrofolate synthetase
Thein_2196	ENOG4105C5F	glutamine synthetase
Thein_2197	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Thein_2198	ENOG4108YZA	Nitrogen regulatory protein pii
Thein_2200	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Thein_2201	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Thein_2202	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Thein_2205	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Thein_2206	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Thein_2207	ENOG41089BK	Glutamine amido-transferase
Thein_2208	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Thein_2209	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Thein_2210	ENOG4105D06	uba thif-type nad fad binding protein
Thein_2212	ENOG4105CHM	Aminotransferase
Thein_2213	ENOG4105DZS	Phenylacetate-CoA ligase
Thein_2214	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Thein_2216	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Thein_2219	ENOG4105BZU	Histidine kinase
Thein_2224	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Thein_2226	ENOG4105CE1	Ferrous iron transport protein b
Thein_2228	ENOG4108JVH	Protein of unknown function DUF43
Thein_2229	ENOG4105MRR	Transcriptional regulator (By similarity)
Thein_R0030	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)